LOCUS       DS264584               12368 bp    DNA     linear   CON 25-MAY-2007
DEFINITION  Bacteroides ovatus ATCC 8483 Scfld0231 genomic scaffold, whole
            genome shotgun sequence.
ACCESSION   DS264584
VERSION     DS264584.1  GI:148337776
DBLINK      BioProject: PRJNA18191
            BioSample: SAMN00627058
KEYWORDS    WGS.
SOURCE      Bacteroides ovatus ATCC 8483
  ORGANISM  Bacteroides ovatus ATCC 8483
            Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
            Bacteroides.
REFERENCE   1  (bases 1 to 12368)
  AUTHORS   Sudarsanam,P., Ley,R., Guruge,J., Turnbaugh,P.J., Mahowald,M.,
            Liep,D. and Gordon,J.
  TITLE     Draft genome sequence of Bacteroides ovatus (ATCC 8483)
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 12368)
  AUTHORS   Fulton,L., Clifton,S., Fulton,B., Xu,J., Minx,P., Pepin,K.H.,
            Johnson,M., Thiruvilangam,P., Bhonagiri,V., Nash,W.E., Mardis,E.R.
            and Wilson,R.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-MAR-2007) Genome Sequencing Center, Washington
            University School of Medicine, 4444 Forest Park, St. Louis, MO
            63108, USA
COMMENT     Bacteroides ovatus (GenBank Accession Number for 16S rDNA gene:
            X83952) is a member of the division Bacteroidetes. In one
            comprehensive 16S rDNA sequence-based enumeration of the colonic
            microbiota of three healthy adult humans, it represents, on
            average, 0.034% of all 16S rDNA sequences and 0.071% of the
            sequences in its division (Eckburg et. al. (2005)). The sequenced
            strain was obtained from ATCC (ATCC 8483T).
            We have collected 6.9X coverage in plasmid end reads and 454 reads.
            We will be performing one round of automated sequence improvement
            (pre-finishing).
            Sequencing/Assembly: The genomic DNA was purified from liquid
            culture derived from a single bacterial colony. A hybrid sequencing
            strategy that utilized reads from both 454 GS-20 and ABI 3730xl
            sequencers was devised and implemented to generate the draft genome
            sequences.  454 reads were assembled using Newbler (454 Life
            Sciences) into 454 de novo contigs. These de novo contigs were
            converted in silico to 800 base paired reads ('superreads') with
            400 base overlaps with neighboring superreads.  Finally, PCAP
            (Huang, et al, Genome Research, 13:2164, (2003)) was used to
            assemble the super-reads and the conventional 3730xl capillary
            reads.
            This sequenced strain is part of a comprehensive, sequence-based
            survey of members of the normal human gut microbiota.  A joint
            effort of the WU-GSC and the Center for Genome Sciences at
            Washington University School of Medicine, the purpose of this
            survey is to provide the general scientific community with a broad
            view of the gene content of 100 representatives of the major
            divisions represented in the intestine's microbial community. This
            information should provide a frame of reference for analyzing
            metagenomic studies of the human gut microbiome. Further details of
            this effort are described in a white paper entitled 'Extending Our
            View of Self: the Human Gut Microbiome Initiative (HGMI)'
            (http://www.genome.gov/Pages/Research/Sequencing/SeqProposals/HGMIS
            eq.pdf). These studies are supported by National Human Genome
            Research Institute
            For answers to your questions regarding this assembly or project,
            or any other GSC genome project, please visit our Genome Groups web
            page (http://genome.wustl.edu/genome_group_index.cgi) and email the
            designated contact person.
FEATURES             Location/Qualifiers
     source          1..12368
                     /organism="Bacteroides ovatus ATCC 8483"
                     /mol_type="genomic DNA"
                     /strain="ATCC 8483"
                     /type_material="type strain of Bacteroides ovatus"
                     /db_xref="ATCC:8483"
                     /db_xref="taxon:411476"
     gene            complement(<1..747)
                     /locus_tag="BACOVA_04719"
     CDS             complement(<1..747)
                     /locus_tag="BACOVA_04719"
                     /inference="protein motif:HMMPfam:IPR013610"
                     /inference="similar to AA sequence:INSD:BAD49638.1"
                     /note="KEGG: vfi:VFB02 1.1e-21 traC; DNA primase TraC; COG:
                     COG4227 Antirestriction protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="EDO08863.1"
                     /db_xref="GI:156107118"
                     /db_xref="InterPro:IPR013610"
                     /translation="MAGYRKKNADGPNSEDKALDLFAEMMIEKIEGIQKDWKKPWFTEG
                     ALQWPRNLHGREYNGMNAFMLLLHCEKEGYKIPRFCTFDCVQKLNKSGKDGEELPRVSV
                     LRGEKSFPVMLTTFTCIHKETKEKIKYDDYKKLSDDEKEQYNVYPKMQVFRVFNVAQTN
                     LQEARPELWQKLEQENSRPAIEEGEHYSFAPVDTMIRDNLWICPITPKYQNDAYYSITK
                     NEIIVPEKEQFRSGESFYGTLFHEMTHSTGAEGVLDRFKPTTFGSPEYAREELVAELGS
                     ALVAQRYGMTKHIKEESCAYLKGWLDELKESPQFIKTTLLDVKRATSIITQKVDKIAQE
                     LEQNVGEKQENGAAAKEKTFYSSVAYLQFSDDTRPLDELREKGDCEGLLTLAKEYYDGN
                     GINEQHTYLSATNNKGDSLIAEDENFAVVYNGSVGGTYEVMLKFTEQEIRDHIRRYGVD
                     IAGETIKEVAREMAAEQFSALAHQKIPAFEMPNGDVLYVEYNKDSDMLDVGQPTNAGLV
                     AQHRFPYDHNIGLDANLQAVNEKLNELEEYRAELQEAEYSVGMRR"
     gene            complement(753..1409)
                     /locus_tag="BACOVA_04720"
     CDS             complement(753..1409)
                     /locus_tag="BACOVA_04720"
                     /inference="protein motif:ScanRegExp:IPR001209"
                     /inference="protein motif:superfamily:IPR008994"
                     /inference="similar to AA sequence:INSD:BAD49637.1"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="EDO08864.1"
                     /db_xref="GI:156107119"
                     /db_xref="InterPro:IPR001209"
                     /db_xref="InterPro:IPR008994"
                     /translation="MYHLSDDPCIIKDKKQMIKCNVTVCGVIGRDASVRKNREEKEFMA
                     FPLRVQIPATGGRHTIEVDVRKECSQEEATGYRNGSRVEVRGTMYLKRRGDKLYFNLFA
                     DEICNAATDDADCVKGELAFRGKVGQNIEEKRDKKDQPYTVFSAFSAEKVDDGFEYQWV
                     RFFCFGKERDAWLQPGIKVDAIGEMNLSAHNGKINLSCKVEELTQYVADSSNYNQ"
     gene            complement(1444..1620)
                     /locus_tag="BACOVA_04721"
     CDS             complement(1444..1620)
                     /locus_tag="BACOVA_04721"
                     /inference="similar to AA sequence:INSD:BAD49636.1"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="EDO08865.1"
                     /db_xref="GI:156107120"
                     /translation="MVKCVMIQLCKCLAGVSILALHVRFCYLLLGWIGTLVVVGVQLAI
                     AGWMVWAMIRAPD"
     gene            complement(1633..3189)
                     /locus_tag="BACOVA_04722"
     CDS             complement(1633..3189)
                     /locus_tag="BACOVA_04722"
                     /inference="protein motif:HMMPfam:IPR002886"
                     /inference="protein motif:HMMPfam:IPR002901"
                     /inference="protein motif:HMMSmart:IPR013338"
                     /inference="protein motif:superfamily:IPR011054"
                     /inference="similar to AA sequence:INSD:BAD49635.1"
                     /note="KEGG: tbd:Tbd_1629 1.4e-14 mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase K02395; COG: COG0739
                     Membrane proteins related to metalloendopeptidases"
                     /codon_start=1
                     /transl_table=11
                     /product="GH73"
                     /protein_id="EDO08866.1"
                     /db_xref="GI:156107121"
                     /db_xref="InterPro:IPR002886"
                     /db_xref="InterPro:IPR002901"
                     /db_xref="InterPro:IPR011054"
                     /db_xref="InterPro:IPR013338"
                     /translation="MSKNQEYALQYADYAMAQMRRYGIPASVTLAQGILESSNGQSRLA
                     RNENNHFGIKATPSWIAGGGKYGIYTDDKPNEKFCSYDSVGDSYEHHSRFLKENSRYAG
                     CFKLSPDDYKGWAQSIEKAGYATGGKYAENLQKIIEQNGLQKYDRQVMQEMAAQGRQFG
                     VEHNPLQTSEGAEHGTGYSFPVEREEFLFITSPFGTRQDPLDGTKQQMHKGVDIRCKGD
                     AVLATENGGKVVAVNQNKNTPGGKSLTVEYARTDGSKVQCTYMHLKEISVKVGDTVQAG
                     GRLGTSGNTGTRTTGEHLHFGVKNIYADGTKRDIDPAAYLAEIAQKGHIKLQMLHNGND
                     LLAKYKAAEDTVPEKNLSPDGWMKKLLSSEDSGVGMSGCNDPIVEMAMTAFASLMLLAT
                     QIDNRNEEEQKAMISTAMDLRTIDLKPLLPNMKNCDLTIGENGKAILKADNGELRVSRE
                     LTASELNRLSATLNNGTLTEETKRMRVTGMLNTVILSEAASQNFEQEMSRQQGQTENLR
                     R"
     gene            complement(3202..5463)
                     /locus_tag="BACOVA_04723"
     CDS             complement(3202..5463)
                     /locus_tag="BACOVA_04723"
                     /inference="protein motif:HMMPfam:IPR007695"
                     /note="COG: COG0249 Mismatch repair ATPase (MutS family);
                     Psort location: Cytoplasmic, score:8.96"
                     /codon_start=1
                     /transl_table=11
                     /product="MutS domain I protein"
                     /protein_id="EDO08867.1"
                     /db_xref="GI:156107122"
                     /db_xref="InterPro:IPR007695"
                     /translation="MKEKSQIEKKAEARQAELLSAALSGASNAGGHWLNVSGKGFPRLY
                     PQGVSASPFNALFMALHSDNNGCKTNLFTLYSETKVRGAAVREHEQGVPFLFYNWNKYV
                     NRNNPDETIDRTAYLQLDEEHKAQFKGVHNREIRTLFNIDQTTLPYVDKPAYEDAVKQD
                     GSVQERGYTEADNRRLRTRFNDFLLKMRDNLVPVRSDGSGVPHYETDKDAVYMPRQKDF
                     EHYHDYMQEALRQIVSATGHQQRLAREGMVMKNGVAPSEDAVKYERLVVELASGIKMLE
                     LGLPARLSDASLKTVDYWCREFKENPCMMDALESDVNNALDVIRKAERGEKIEYATLRN
                     RRQTTTMQEQMHKHYFVANEIRQHPDKAAKSIVLVIDREAKSADVILPAGASTEANNEI
                     PGMNKGRIERALQKEGIEQVRFYNTDGALGYRPDDSYFNEKMVTLARLRNYTLEKLSTL
                     DVSEAVRRANEVGFDAVQMIQDDKNRWALYIKPENKEGYSVYPDKEDVNRFFSTLKQAM
                     DNIDKVRMELAHKYYALAEVKPDLKVDLFGSDTPEIDLNRIQRVAIFKTRQDGIQCVAT
                     IDGQKLQPRSVTPQQWQRMWVAEDRDGYKRHLAATLFADVLQKGQSVGEQKAEEQVRQQ
                     NETVPENRSEETNDENMSPKRQFWDNLKEKHPDALYLIRAGEVYRLYNEDAAKGAKILG
                     ITVKEYPEHGFSTFAEFPRTQLDSYLPKLVRAGERVAISEIELQDKRQDEQETHRGIHR
                     "
     gene            complement(5491..7290)
                     /locus_tag="BACOVA_04724"
     CDS             complement(5491..7290)
                     /locus_tag="BACOVA_04724"
                     /inference="similar to AA sequence:INSD:BAD49633.1"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="EDO08868.1"
                     /db_xref="GI:156107123"
                     /translation="MDGIKHSRQFAEMERLVSDYFHCHLAPVMSKTQAYLTKKQGEEMR
                     EYSTSLGGILSAMASAAQPMGDPYQVLKVTGEWNSKTTEDYIGMCKAEITGSKEIQQDL
                     AYMAGQWRDTVVQEIGRKRYDELSEQLGGDLAYAYMDYRVEELMIDRLVKERMPKSSAD
                     YIIRKAAESSLLGLSQTFNRSPLAVEIEARGEAAYRPKGWEKGAGRVLGATADTVMMGG
                     VGSWATLAKFVGADVAISAVASRFEPEKPDTLSVEECISKGVFGSERNVFTDFRKEAAT
                     VQTGDSALIVAANERLKKKIPVMDFSFPKWMQTPKFTPFQMPEIPGHPEKKNERAERYK
                     DVPLVVAPGQEEAYLKHLEKYKNATAVTAKKESTQPETEQREKVEKEERQVVIPREEEK
                     QEREAVQTNTNGWSGLLSTLGLEGLGDITGNLGYVMAMLPDILLGAFTGKTQSLRFGDN
                     LLPIASIVAGLFVRNPLLKMLLVGLGGANLLNKAGHEALGRPMPSAAEQTENQYRRYPD
                     EPLNPRIVNPVLQGSTLIATIDRVPCTIQLTPTVAEAYRAGALPLNTLANAVLAKSDQL
                     RHIASQNYDDGQRETVVRTRGIQ"
     gene            complement(7299..7580)
                     /locus_tag="BACOVA_04725"
     CDS             complement(7299..7580)
                     /locus_tag="BACOVA_04725"
                     /inference="similar to AA sequence:INSD:ABP57344.1"
                     /note="Psort location: Cytoplasmic, score:8.96"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="EDO08869.1"
                     /db_xref="GI:156107124"
                     /translation="MAELDIDIQSFDIPRLVTVYPDRAGVRWWTKAWFNNREEGETSVE
                     IEREQAIRFMQDNIEKDAWLEEFFPRQMEVYHNAIEQTKEQLLKQINI"
     gene            complement(7604..8434)
                     /locus_tag="BACOVA_04726"
     CDS             complement(7604..8434)
                     /locus_tag="BACOVA_04726"
                     /inference="protein motif:HMMPfam:IPR002886"
                     /inference="protein motif:superfamily:IPR011054"
                     /inference="similar to AA sequence:INSD:ABP57343.1"
                     /note="KEGG: ava:Ava_C0210 3.3e-08 peptidase M23B K08259;
                     COG: COG0739 Membrane proteins related to
                     metalloendopeptidases"
                     /codon_start=1
                     /transl_table=11
                     /product="STP|Peptidase_M23"
                     /protein_id="EDO08870.1"
                     /db_xref="GI:156107125"
                     /db_xref="InterPro:IPR002886"
                     /db_xref="InterPro:IPR011054"
                     /translation="MKYTEEMILQSDSGYCMPFEEQQGKDVELSLGYGEQTDPVTGEKF
                     FHHGIDFNVRCYMLSALASGIVSGVGNDSGHGICQTIRYGEYEVTYGNLSNVFAQFGQR
                     VKAGQTVALSGDKLHMTVRFKGEELNPLEFLTMLYGNIQAMRQAGGHETDYPSGVEMEL
                     GTDYDRDKREIEELMLRFLPHYMEDLRHGAYTLPRNTEQSLRHIFTVGAMKEYFYENMP
                     SMANPLGLGHKAMPLACKVQNLLIADFLHYLALRHDVYLSTAGSDIKKNSMTKP"
     gene            complement(8459..9124)
                     /locus_tag="BACOVA_04727"
     CDS             complement(8459..9124)
                     /locus_tag="BACOVA_04727"
                     /inference="similar to AA sequence:INSD:ABP57342.1"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="EDO08871.1"
                     /db_xref="GI:156107126"
                     /translation="MGVWSTLLKYGGKAAKGVGTATAATGKSMGKAVLHPSQTLRGAGQ
                     AVKTATIGGAIGYVGWEKLTTDKSVVRIVSDAVVGESVTDTIAGTADGVRELTGKAGEA
                     VSSVSGAVTGIDNKLNGVSNFLRQASGGGGLDMFGNFFRNLGSGNVSGLSIAGLVAAAF
                     LIFGRFGWLGKIAGAFLGMMLIGNNAGVFRTPETENVQRTRTPDFSAGEQAHGGGMRR"
     gene            complement(9139..9822)
                     /locus_tag="BACOVA_04728"
     CDS             complement(9139..9822)
                     /locus_tag="BACOVA_04728"
                     /inference="similar to AA sequence:INSD:BAD49629.1"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="EDO08872.1"
                     /db_xref="GI:156107127"
                     /translation="MKRTIWIGILLLCIGIGKARAQNDPVLAGMILLYTDKAEKELKKQ
                     EKVMLMQTTGHLWTKEEVKATTDLQREFNSYLDSFRSIVCYAAQIYGFYHEISKLTDNM
                     GDFTRQVSRNSSHALAVALSTQRNRIYRELIMNSVEIVNDIRMACLSDNKMTEKERMEI
                     VFGIRPKLKMMNKKLQRLTKAVKYTTMGDIWREIDEGARPVAGKRDIVEAAKRRWRQIG
                     RNVRP"
     gene            complement(9837..10526)
                     /locus_tag="BACOVA_04729"
     CDS             complement(9837..10526)
                     /locus_tag="BACOVA_04729"
                     /inference="similar to AA sequence:INSD:BAD49628.1"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="EDO08873.1"
                     /db_xref="GI:156107128"
                     /translation="MKSRIISLVIFAVCMMPHWAKAQITASNPLEWMALAEGNEVINDQ
                     IEKQINGQTKTAMLQNSIAAEFNRIHKWEKQYNSYLKTASGYASSLKACTHLYNDGVRI
                     FLTLGKLGNAIRNNPQGIIASISMNNLYIETATELVSVFTLLNDAVAKGGKENMLTGAE
                     RSKTLWALNDKLSAFSRKLHLLYLSIRYYTLNDMWNNVTAGMLDRNNGEAARMAMTRWR
                     RAAVLAR"
     gene            complement(10507..11004)
                     /locus_tag="BACOVA_04730"
     CDS             complement(10507..11004)
                     /locus_tag="BACOVA_04730"
                     /inference="similar to AA sequence:INSD:ABP57339.1"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|F0R7G3|9.B.154.1.2"
                     /protein_id="EDO08874.1"
                     /db_xref="GI:156107129"
                     /translation="MMTDAPTGHFQSIVLQPHAGQFVIDELPAIVLCCAAWVYGGMEGL
                     PLTALAVSVAALLALVLLYRFIYLRRTRYHIGSEQLISRHGVLSRKTDYMEQYRIVDFV
                     EHQNLMQQLCGLKTVRIFSMDRNTPRLDLVGIRHNFDVVTLIRERVEYNKRKKGIYEIT
                     NH"
     gene            complement(11001..>12368)
                     /locus_tag="BACOVA_04731"
     CDS             complement(11001..>12368)
                     /locus_tag="BACOVA_04731"
                     /inference="similar to AA sequence:INSD:BAD49626.1"
                     /note="COG: NOG33027 non supervised orthologous group;
                     Psort location: Cytoplasmic, score:8.96"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="EDO08875.1"
                     /db_xref="GI:156107130"
                     /translation="MREGELTYDDFLRRLNIQDVLIDAGYHLNRRDGLRYPSYVRLDSE
                     GRRIRNDKFIVTQQGKCCFKPQQQKSYNIISFIKEHPHFFAEYRTGVSPDRLVNLVCNR
                     LLNHPVADRDIRIIQPKRDVKPFDMADYDIHQFNPQDRATQKKFYPFFKHRGIDLYTQY
                     AFHRNFCLATKHREDGMKYTNLAFPLTVPKDTGQVVGLEERGRPRMDGSGSYKGKAEGS
                     NSSQGLWIASPAKTTLTEAKHIYWFESAYDAMAYYQLHQANDKDLRKAVFISTGGNPTV
                     EQMRGVLTLSLPAKQHICFDTDLAGIEFAKNLQQEMYRVVRSTIEETPERKPYLDSVTD
                     GKNLDEGDIDLLPDALRSSYGKYESAWEEAMSMRSSGLCHPDDIREQTDIMNGNYKEFR
                     EGLREFLGLDKANDASFVREQPTYPNKDWNEQLLAEQKQEETVDETQAREQSPEEEQQT
                     HFRR"
ORIGIN
        1 gtgcgtcatc tcatggaaca gtgtcccgta aaacgattct cccgatctga actgttcctt
       61 ttccggcacg atgatttcat tcttcgtgat ggaatagtag gcgtcattct gatatttcgg
      121 cgtaatcgga caaatccaca ggttatccct tatcatcgta tcgactgggg caaaactgta
      181 atgctcgccc tcctcgattg ccggacgcga attttcctgc tccagttttt gccacagctc
      241 cggtcgcgct tcctgcaaat tggtctgcgc aacattgaag accctgaaaa cctgcatctt
      301 cggataaaca ttgtactgtt ccttttcgtc atcggagagt ttcttgtaat cgtcatactt
      361 gattttctcc ttggtctcct tatggataca agtgaacgtg gtgagcatga ccggaaagga
      421 cttctcgcca cgaagcacgg agacacgcgg cagttcctct ccatccttgc cggacttatt
      481 gagcttctga acacaatcga aggtgcagaa acggggaatc ttgtaccctt ctttctcgca
      541 gtgcaaaagc agcataaaag cattcatccc gttgtactcg cgcccgtgaa ggttgcgagg
      601 ccactgcaac gcaccctcgg taaaccaagg ctttttccag tccttttgaa tgccctcgat
      661 tttctcgatc atcatttcgg cgaacaggtc gagagccttg tcctcgctgt tcggtccgtc
      721 ggcattcttc tttctgtaac cggccatatt acttactgat tatagttaga cgaatccgcc
      781 acatattgcg tcagttcctc caccttgcag gaaagattga ttttcccgtt atgtgccgac
      841 aggttcattt cacctatggc atccaccttt atacccggct gtagccacgc atcgcgctcc
      901 ttgccgaaac agaagaagcg cacccactgg tattcgaagc cgtcatcgac cttctccgca
      961 ctgaacgccg agaacaccgt ataaggctgg tctttcttat cccttttctc ctcgatattc
     1021 tggccgactt taccacgaaa tgccagctca cccttgacgc aatccgcatc atccgtagcg
     1081 gcattgcaga tttcatcggc gaacaggttg aaatagagct tgtcaccccg gcgtttgaga
     1141 tacatcgtac ccctcacttc cacacgggag ccgttccgat aaccggtggc ttcttcctga
     1201 ctgcactcct tgcggacatc cacctcgata gtatgccgtc cacccgttgc cggaatctgt
     1261 acccggagcg gaaatgccat aaactccttt tcctctctgt tcttgcgaac cgacgcatcg
     1321 cggccgataa cgccgcatac cgtaacatta catttaatca tctgtttttt gtctttaatg
     1381 atacatggat catccgacaa gtgatacatg ggttgattga tgttgaactg ttggagggta
     1441 cggtcagtca ggcgcacgta tcatcgccca gaccatccat ccggcgatgg ctaattgcac
     1501 gcccacgaca acgagcgtcc cgatccaccc caacagcagg tagcagaacc ggacgtgcaa
     1561 cgcaaggatg gagactcccg ccagacattt gcatagctgt atcatcacgc attttaccat
     1621 atcgccatgc ctttatcttc gcaggttttc cgtctgtccc tgttgccggg acatctcttg
     1681 ctcgaaattc tgtgaggccg cttccgacag gataaccgta ttcagcatac cggttacacg
     1741 catccgtttg gtctcttccg tgagtgtgcc gttgttcaac gtggcagaca accggttcag
     1801 ctcggaagcg gtcagctccc gcgagacacg cagttcccca ttgtccgctt tcagaatggc
     1861 cttgccgttc tcgccgatag tcaggtcgca gttcttcata ttcggcaaca acggcttcag
     1921 gtcgatggta cgaagatcca tcgcggtgga tatcatcgcc ttctgttcct cttcgttccg
     1981 gttgtcaatc tgtgtggcca gcagcatcag ggaggcgaaa gcggtcatcg ccatctccac
     2041 aatcgggtcg ttgcatcccg acattcccac accgctatcc tccgacgaaa ggagtttttt
     2101 catccatccg tcgggcgaaa ggttcttttc aggcacggta tcttccgccg ccttgtattt
     2161 ggcgagcagg tcattcccgt tgtgcagcat ttgcaatttg atatgtcctt tctgtgcgat
     2221 ttcagccaga tacgccgcag ggtctatatc ccgtttcgtc ccgtcggcat agatattctt
     2281 cacaccgaaa tgcagatgtt ccccggtcgt ccgtgttccc gtattgcccg atgtgccgag
     2341 ccgtccgccg gcctgtaccg tatcgccgac cttgacggaa atctccttga ggtgcatata
     2401 ggtacattgt accttgctgc cgtccgtccg ggcatattcc accgtcagcg acttgccgcc
     2461 gggcgtattc ttgttctggt ttaccgccac gaccttgccg ccgttctccg tagccagtac
     2521 cgcatcgcct ttgcaacgta tatccacgcc cttgtgcatc tgttgctttg tgccgtccaa
     2581 cgggtcttgc cgtgttccga acggagaggt aatgaacaga aattcctccc gttccaccgg
     2641 gaacgaatac cccgttccat gttccgcacc ttcggaggtc tggagcggat tgtgttctac
     2701 cccgaactgc ctgccttgtg ccgccatctc ctgcatcacc tgcctgtcat acttctgcaa
     2761 gccgttctgc tcaatgattt tttgcaggtt ctcggcatac ttgccgcctg tggcgtaacc
     2821 ggctttctca atgctttgtg cccagccctt gtaatcgtcc ggggagagtt tgaagcaacc
     2881 ggcatagcgg ctgttctcct tcaaaaagcg ggagtgatgc tcgtatgaat cacccacgct
     2941 gtcatagctg cagaactttt cattcggctt atcatcggtg tagattccgt atttgccgcc
     3001 tccggcaatc cacgagggtg tcgccttgat gccgaaatgg ttgttctcgt tcctcgccag
     3061 acggctctgt ccgttgctgc tttccagtat gccttgcgcc aatgtgacgg aagccggaat
     3121 gccatacctg cgcatctgtg ccatcgcata atccgcgtat tgcagtgcat attcctgatt
     3181 cttgctcata atcgtcactc cttatctatg aataccccta tgtgtttcct gctcgtcctg
     3241 ccgtttatcc tgtagctcta tctcactgat ggcgacacgc tcaccggcac ggacaagttt
     3301 gggcagatag ctgtccagtt gcgtccttgg gaactctgcg aaagtcgaaa atccatgttc
     3361 cggatattcc ttgaccgtaa ttcccagtat ttttgctccc tttgccgcat cctcattata
     3421 aagccggtac acttctcctg cacgaatcag atacagggcg tcgggatgct tttccttgag
     3481 gttgtcccaa aactgccgtt tcggagacat attttcatca ttcgtctctt ccgaccgatt
     3541 ttccggcacc gtctcattct gttgccgtac ctgctcttcc gctttctgtt ccccgacgga
     3601 ttgtcccttt tgcagcacat cggcaaacag cgtggccgcc aaatgccgct tgtagccgtc
     3661 ccggtcttcc gccacccaca tccgttgcca ctgctgtgga gtgacgctgc ggggctgcag
     3721 cttttgtccg tcgatggttg ccacacactg gattccatcc tgcctggtct tgaagatggc
     3781 aacacgctga atacggttca ggtcaatctc cggcgtatcg ctgccgaaca aatccacttt
     3841 caggtcgggc ttgacctccg ccagtgcata atacttgtgc gccagctcca tccgtacctt
     3901 gtcgatgttg tccatcgcct gcttgagcgt ggagaaaaaa cggttcacat cctccttatc
     3961 gggatagacg ctgtacccct ccttgttttc cggcttgata tagagtgccc aacggttctt
     4021 gtcgtcctga atcatctgca cggcatcgaa cccgacctca ttcgcccgtc tgaccgcctc
     4081 cgacacgtcc agcgtggaga gcttttccaa cgtgtagttc cttaaccggg ccagtgtcac
     4141 cattttttca ttgaaatagc tgtcatcggg tctgtagccc aatgcaccgt cagtattata
     4201 gaaacgcacc tgctcgatac cctctttctg caatgcccgt tcgatacgtc ccttgttcat
     4261 gccgggaatc tcgttgttcg cctcggtcga agctcctgcc ggcaaaatga catctgccga
     4321 ttttgcctcc cggtctatga cgaggacgat gcttttcgcc gccttgtccg ggtgctggcg
     4381 gatttcattc gccacaaagt aatgcttgtg catctgttcc tgcatggtcg tggtctgccg
     4441 tctgtttcgc agggtggcgt actcaatttt ctcgccccgt tccgcttttc ggataacatc
     4501 aagcgcattg ttcacgtcgc tttcgagagc gtccatcata cacggatttt ccttgaactc
     4561 ccggcaccag taatccaccg tcttcaggct tgcatcggac agacgggcgg gcagtcccag
     4621 ttccagcatt ttgatacccg aagccagttc cacgaccaac ctttcatatt ttaccgcatc
     4681 ctccgacggg gccacgccgt tcttcatgac catgccttca cgggcgagcc gctgttgatg
     4741 ccccgtagca ctcacgatct gccgcaaggc ttcctgcata taatcgtggt aatgttcaaa
     4801 atccttttga cgcggcatat agaccgcatc tttgtccgtc tcgtaatgag gaactccgct
     4861 accgtccgag cgcacgggaa cgaggttgtc ccgcatcttc aatagaaagt cgttgaaccg
     4921 ggtgcgcaac ctgcggttgt ccgcctcggt atatcctctt tcctgaacac tgccatcctg
     4981 ctttaccgca tcctcgtaag ccggcttgtc aacgtagggc aacgtcgtct ggtcgatatt
     5041 gaaaagcgtg cggatctccc ggttgtggac acccttgaac tgtgccttat gctcttcgtc
     5101 caattggaga taggcggtac ggtcgatggt ctcatccgga ttgttccggt tgacatactt
     5161 gttccagtta tagaacagga acggtacgcc ctgctcatgc tcccgcaccg cagcaccccg
     5221 taccttggtt tcactgtaaa gcgtgaacag gttggtcttg catccgttat tgtccgaatg
     5281 caaggccata aagagggcat tgaacgggct ggccgagacc ccttgcggat agagccgggg
     5341 aaatcccttg cccgatacgt tgagccaatg gccgccagcg ttcgacgccc cgctcagtgc
     5401 ggcagacagc agttccgcct gccttgcctc ggctttcttc tcgatttgcg acttttcttt
     5461 catatcatca tgcttttatt gttcatggaa ttattggatg ccccgtgtac gcacgaccgt
     5521 ttcccgctgt ccgtcatcgt aattctgcga agcgatatgg cgcaactggt cgctcttggc
     5581 aagcacggcg ttcgccagcg tgttcagcgg caatgcccct gcacggtaag cctccgcgac
     5641 ggtcggcgtg agctggatgg tacaaggcac acggtctatc gtggcgatga gcgtactgcc
     5701 ttgcagtacc gggttcacaa tacggggatt gagcggttca tcgggataac ggcggtactg
     5761 gttctccgtc tgttcggcag cggacggcat gggtcgcccc aaagcctcgt gtcccgcctt
     5821 gttcagcagg tttgcgccgc ccagaccgac aaggagcatc ttcagcagcg ggttacgcac
     5881 gaacagaccg gccacaatac tcgctatcgg cagcaggttg tccccaaagc gcaacgattg
     5941 tgtcttgccg gtaaaagccc ccaacaggat gtcgggcagc atggccatga catatccgag
     6001 gttgcccgtg atatcgccca atccctctaa tcccaacgta ctgagcaatc cgctccatcc
     6061 gttcgtgttg gtctgcacag cctctctctc ttgcttttct tcctcacgtg gaataaccac
     6121 ctgccgttcc tctttctcca ctttttccct ctgttccgtc tccggctgcg ttgattcctt
     6181 tttggcagtt acagccgttg cattcttata tttctccaaa tgcttcaaat aggcttcttc
     6241 ctgtccggga gcgacgacca gcggcacatc cttgtaccgt tcggcacgtt cattcttctt
     6301 ttcagggtgt ccgggtattt ctggcatttg gaaaggggta aactttggtg tctgcatcca
     6361 cttcgggaaa ctgaaatcca tcaccggtat tttcttcttc aaccgctcgt tggcggccac
     6421 gatgagcgca ctgtcacccg tctgtaccgt tgcagcctcc ttgcggaagt ccgtaaatac
     6481 gttccgttcg ctgccgaaca cccctttgct tatacactct tccacagaaa gcgtatcagg
     6541 cttttcaggc tcgaagcgtg aggcgactgc cgagatagcc acgtccgccc cgacaaactt
     6601 cgccagtgtt gcccacgaac ccacgcctcc catcatcacg gtatctgccg ttgcgcccag
     6661 tacccgaccc gcgccttttt cccatccttt cggacggtag gcggcttcgc cccgtgcctc
     6721 gatttccaca gcaagcggcg agcggttgaa ggtctgcgaa agtccaagca ggcttgattc
     6781 tgcggctttg cggatgatgt agtcggctga cgatttcggc atacgctcct tgaccagccg
     6841 gtcgatcatc agttcctcca cccggtagtc catataggca taggcaaggt cgccgcctaa
     6901 ttgttccgac agttcatcgt aacgcttgcg cccgatttcc tgcacgacag tatcgcgcca
     6961 ttgcccggcc atgtatgcga ggtcttgctg tatctctttg gagccggtaa tctccgcctt
     7021 gcacattccg atatagtcct ccgttgtctt cgagttccat tcgcccgtga ccttgagtac
     7081 ctggtacggg tcgcccatcg gctgtgccgc agacgccatc gcgctgagta tgccgcccaa
     7141 agaggtggaa tactccctca tttcctcgcc ctgtttcttc gtgaggtaag cctgtgtctt
     7201 cgacatgacg ggcgcaaggt ggcagtggaa atagtcgctc acgaggcgtt ccatttctgc
     7261 gaattgccgg ctatgtttga ttccatccat attgtgtatt atatatttat ctgtttcaat
     7321 aactgttctt tcgtctgctc gatggcgttg tggtaaacct ccatctgccg gggaaagaac
     7381 tcttccagcc atgcgtcctt ttcgatgttg tcctgcatga accgtatcgc ctgctcccgt
     7441 tcgatttcga cggatgtctc gccctcttcc ctgttgttga accatgcctt cgtccaccag
     7501 cgcacacccg cccggtcggg atagaccgtg acaagcctcg gtatgtcgaa actctgtatg
     7561 tcgatgtcca gttccgccaa cgggtctatg atgccgccat aggtcagggc ttcgtcatgg
     7621 agtttttttt tatgtcactg cccgcagtgg agaggtacac atcatgccgc agggcgaggt
     7681 aatgcaggaa atccgcaatc aggaggttct gcaccttgca ggccagcggc atggccttat
     7741 gtcccagtcc gagcggattg gccatgctcg gcatattctc gtagaaatac tccttcatcg
     7801 cacccaccgt gaagatgtgg cgtagcgact gctccgtatt tcggggcaag gtgtatgctc
     7861 catgccgcaa atcctccata tagtgcggca ggaagcgcag catcagttcc tctatctctc
     7921 tcttatcccg gtcataatcg gttcccagtt ccatctctac accggaggga tagtcggttt
     7981 cgtgtccgcc ggcctgacgc attgcctgga tattcccgta cagcattgtc aagaattcca
     8041 acggattcag ttcctcgccc ttgaagcgga cggtcatgtg cagtttgtca ccgctcaaag
     8101 ctaccgtctg tccggccttt acacgctgtc cgaattgggc gaagacattg gacaggtttc
     8161 cgtatgtcac ctcatattcc ccgtagcgga tggtctggca gatgccgtgt ccggaatcgt
     8221 tgcccacgcc cgacacaatg ccgctggcaa gggcggaaag catatagcac cgcacgttga
     8281 agtcaatgcc gtgatgaaag aatttctcgc ccgtcaccgg gtcggtctgt tcgccgtagc
     8341 cgagcgacag ctccacgtct ttgccctgct gttcctcgaa aggcatacaa taaccgctat
     8401 cggattgcag gatcatttct tctgtatatt tcatgctgtt tccattttga ttcgtattct
     8461 atcttctcat tcctccgcca tgtgcctgtt cccctgccga aaagtcaggt gtacgggtac
     8521 gttgcacgtt ttctgtctcc ggcgtgcgga agacacccgc attgttgccg atgagcatca
     8581 tgccgagaaa tgcgccggca atcttgccca gccagccgaa gcgtccgaat atgaggaacg
     8641 ccgccgcaac cagtccggcg atgctcaacc ctgacacgtt gccgctgcca aggttgcgga
     8701 aaaagttgcc gaacatatca agacctccgc caccggaggc ctgtcgcaaa aagttcgaca
     8761 cgccgttcag tttgttgtcg atgccggtta ccgcaccgct gaccgaactg acggcttctc
     8821 cggccttgcc cgttagttca cgcacgccgt ccgccgtgcc tgcaatggta tccgtgacgg
     8881 attcgcccac aacggcatcg ctcacgatac gcaccacgct tttgtcggtg gtcagcttct
     8941 cccagcccac ataaccgatc gcaccgccga tagtcgctgt cttgactgcc tgtcctgcac
     9001 cacgcaaggt ctgcgaaggg tgcagcactg ccttacccat acttttgccg gtagccgccg
     9061 ttgccgtacc gacacctttt gcggccttgc cgccatattt caatagtgta ctccaaacgc
     9121 ccatacattg tctgtttttt aaggtcttac atttcttcca atctgccgcc agcgtcgctt
     9181 ggcagcttcc actatgtccc gtttgccggc caccggacgt gctccctcgt cgatttcacg
     9241 ccagatgtcg cccattgtcg tgtacttcac cgccttggtc agccgttgca gtttcttgtt
     9301 catcatcttg agcttcggac ggatgccgaa tacgatttcc atgcgctctt tctccgtcat
     9361 cttgttgtcc gaaaggcacg ccatgcggat gtcgttcaca atctccacgc tgttcatgat
     9421 cagttcccgg taaatccggt ttcgttgcgt ggagagggcg acggccaacg catgggagct
     9481 gttccggctc acctgtctgg taaagtcacc catgttatcc gtcagcttcg atatttcgtg
     9541 atagaaaccg tatatctgcg ccgcgtagca gactatcgac cggaaagagt ccagatagct
     9601 gttgaactcc cgttgcaggt cggtcgtggc tttcacttcc tctttcgtcc acaggtgtcc
     9661 ggtggtctgc atcagcatga ctttctcctg tttcttcagc tccttttccg ccttgtcggt
     9721 atagagcagg atcattccgg ccagtacagg gtcgttttgc gcccgtgcct tgccgatgcc
     9781 gatgcacaac aataagatgc ctatccaaat cgtccgtttc attgtcagtt ccgtttttat
     9841 cgtgcgagga cggcagccct gcgccaacgg gtcatggcca tccgtgccgc ctccccattg
     9901 ttgcggtcga gcatcccggc cgtcacattg ttccacatgt cattgagggt atagtatcgt
     9961 atgctcaggt agagcaggtg tagcttccgg ctgaaagccg aaagtttgtc gttcaacgcc
    10021 cacagggtct tgctgcgttc cgctcccgtg agcatattct ctttgccgcc cttggccact
    10081 gcgtcattca ggagtgtgaa gaccgatacc agttccgttg ccgtctcgat atagaggttg
    10141 ttcatgctta tggaggcaat gatgccctgc gggttgttcc tgatggcgtt gcccagtttc
    10201 cctaacgtga gaaagattct cacgccgtcg ttgtagaggt gggtgcaggc tttcagcgac
    10261 gaagcgtagc cgcttgccgt cttgagatag ctgttatatt gcttctccca tttgtgaatg
    10321 cggttgaact cggcggcgat gctgttctgc agcatcgctg tcttcgtctg accgtttatc
    10381 tgtttctcta tctggtcatt gatgacctcg ttgccctcgg ccaacgccat ccattccaac
    10441 ggattggatg ccgtgatttg tgctttcgcc cagtgtggca tcatgcagac ggcaaaaatg
    10501 accaggctaa tgattcgtga tttcatatat tccctttttt cgtttgttat actcgacccg
    10561 ttcccggata agcgttacca catcgaagtt gtgtctgata cctaccaaat caagccgggg
    10621 cgtattcctg tccatcgaga atatgcgtac cgtcttcaat ccgcaaagct gctgcatgag
    10681 gttttggtgt tccacaaagt ccacgatacg gtattgttcc atgtagtccg tcttccggga
    10741 cagcacccca tgcctgctga taagctgctc gctaccgatg tggtagcgtg tccggcgcag
    10801 atagatgaaa cggtacagca ataccaaagc aagcaatgcg gcaaccgata cggcaagagc
    10861 tgtcagaggc agtccctcca tgccaccata cacccatgct gcacagcaca atacgattgc
    10921 gggcagctcg tcgataacga actgtccggc gtgcggttgc agcacgatac tttggaaatg
    10981 tcctgtgggt gcatcggtca tcatcggcga aagtgtgttt gttgttcctc ttccggtgac
    11041 tgttctctcg cctgtgtctc atcgaccgtc tcttcctgtt tctgctcggc caaaagctgt
    11101 tcgttccagt ccttgttggg ataggtaggc tgttcacgga caaaagaggc gtcattcgcc
    11161 ttgtccagac cgaggaactc ccgcaatcct tcacggaact ccttgtaatt tccgttcatg
    11221 atatccgtct gttcccgtat gtcgtccgga tggcacaggc cgctcgaacg catcgacatg
    11281 gcttcttccc atgcggattc atatttcccg tagctcgacc gcaaagcgtc gggcaacagg
    11341 tctatgtcac cttcatcgag gttcttgccg tcagtaacgg aatccagata aggcttccgc
    11401 tccggtgtct cctcgatggt ggaacggaca acccggtaca tctcctgttg caggttcttg
    11461 gcaaactcga ttcccgcaag gtcggtatcg aaacagatgt gttgcttggc aggaagcgag
    11521 agcgtgagga caccccgcat ctgttccacc gtcgggttac cgccggtaga tatgaagacc
    11581 gctttccgca aatccttgtc gttggcctga tgaagctggt aataggccat cgcgtcgtat
    11641 gcactctcga accagtagat atgcttggct tcggtaagcg tagttttggc tgggctggca
    11701 atccataacc cttggctcga attgctccct tccgccttcc ctttataact gccgctgcca
    11761 tccatgcgag ggcggcctcg ctcttccaga ccgacaacct gtcccgtatc tttcggaacg
    11821 gtcagcggaa aggcgaggtt ggtgtatttc atgccgtcct cacgatgctt cgtcgccaga
    11881 cagaagttcc gatgaaaggc atactgcgtg taaaggtcga tgccccgatg cttgaagaac
    11941 ggatagaact tcttttgtgt cgcccgatcc tgcggattga actggtgaat gtcgtaatcc
    12001 gccatgtcaa acggcttcac atcccgttta ggctggataa tccggatgtc ccggtcagcg
    12061 acgggatggt tcagcaaccg gttacagaca aggtttacca gtcggtcggg agacacgcct
    12121 gtacggtatt ccgcaaaaaa atgcggatgc tccttgataa aggaaatgat gttatacgac
    12181 ttctgctgtt gcggtttgaa acagcatttc ccttgctgcg tgacaatgaa cttgtcgttg
    12241 cggatgcgcc gcccctcgct gtccaaccgg acatacgagg gatagcgcag gccgtcgcgc
    12301 cggttcaggt gatagcccgc gtcgataagc acgtcctgaa tgttcagcct gcgcagaaaa
    12361 tcgtcata
//
