LOCUS       CP000303                9872 bp    DNA     linear   BCT 31-JAN-2014
DEFINITION  Bifidobacterium breve UCC2003, complete genome.
ACCESSION   CP000303
VERSION     CP000303.1
DBLINK      BioProject: PRJNA13487
            BioSample: SAMN02604112
KEYWORDS    .
SOURCE      Bifidobacterium breve UCC2003
  ORGANISM  Bifidobacterium breve UCC2003
            Bacteria; Actinobacteria; Bifidobacteriales; Bifidobacteriaceae;
            Bifidobacterium.
REFERENCE   1  (bases 1 to 9872)
  AUTHORS   O'Connell Motherway,M., Zomer,A., Leahy,S.C., Reunanen,J.,
            Bottacini,F., Claesson,M.J., O'Brien,F., Flynn,K., Casey,P.G.,
            Moreno Munoz,J.A., Kearney,B., Houston,A.M., O'Mahony,C.,
            Higgins,D.G., Shanahan,F., Palva,A., de Vos,W.M., Fitzgerald,G.F.,
            Ventura,M., O'Toole,P.W. and van Sinderen,D.
  TITLE     Functional genome analysis of Bifidobacterium breve UCC2003 reveals
            type IVb tight adherence (Tad) pili as an essential and conserved
            host-colonization factor
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. (2011) In press
   PUBMED   21690406
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 9872)
  AUTHORS   O'Connell Motherway,M., Zomer,A., Leahy,S., Reunanen,J.,
            Bottacini,F., Claesson,M., O'Brien,F., O'Flynn,K., Casey,P.,
            Moreno-Munoz,J., Higgins,D.G., Shanahan,F., de Vos,W.,
            Fitzgerald,G.F., Ventura,M., O'Toole,P. and van Sinderen,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-MAR-2006) Department of Microbiology, Alimentary
            Pharmabiotic Centre, University College Cork, College Road, Cork,
            Munster, Ireland
COMMENT     Source DNA or strain is available from Douwe van Sinderen,
            d.vansinderen@ucc.ie.
FEATURES             Location/Qualifiers
     source          1..9872
                     /organism="Bifidobacterium breve UCC2003"
                     /mol_type="genomic DNA"
                     /strain="UCC2003"
                     /db_xref="taxon:326426"
     gene            1..1350
                     /locus_tag="Bbr_0417"
     CDS             1..1350
                     /locus_tag="Bbr_0417"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|P94528|3.A.1.1.34"
                     /protein_id="ABE95115.1"
                     /translation="MRNTKKVIAATAAVATLVGLAACGSSNDNSVNKGDADKAELVFWG
                     WDSGNSMKEILADFEKANPGITVKFNNTGTAEKTSTALSNAIAAGNGAPDVVMLEDPTV
                     TQFAVTDGLVDLSRFGADKLADDFAAGPWNKLQYNNKPYALPIDSGPEMFFYNKAVFDK
                     AGVDGESIKTWDDYYEAAKKIRAIGSYITNLAGTSNDYQPFTAQIWQAGAQPWKVDGEN
                     ITINMTKDEGMQRYIQFVQKLIDEDLVDTKTPNWSDDWNRELNDGTLASLTIGAWMPIN
                     LMTGAPDQAGNWRVAQLPQWEDGKEVSAEDGGSALAVTSQSKNQAAAYKLVEYMTHGKG
                     AQTMADTGTFPSLKKILKSDSFTDPTTESNKKTNDYFGGQNVNEVLSAAAQRPTEKFQY
                     LPYNPYAQTAYGDEVSKAYSGDITLEEALQNYAKKLAEQGKQQGYNVTVK"
     gene            1571..2533
                     /locus_tag="Bbr_0418"
     CDS             1571..2533
                     /locus_tag="Bbr_0418"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|D6ZW63|3.A.1.1.48"
                     /protein_id="ABE95116.1"
                     /translation="MSDQTMAAASQPTVGILPEEADLHTAEARVNKHKADWRGWKFMWP
                     FTVVFVFVFIIPIVYAVYISFFKKQMIGGTRFVGVENYARLLQDGQFWSSVGRVALFTC
                     VQVPIMLFLSAAMALALDSMKLHGAKFFRISTFLPYAVPAVVSTLVWGFVYGAKYGLVG
                     SFNDFFGTNVDVLQPGVLLASIGNISTWEFTGYNMLIFYSSLSTIPHSLYEAASIDGAS
                     EWQIVKSIKLPELKGSLAITVIFSIIGSFQLFNEPSILQNMVPGNAITTYYTPNMYAYN
                     LSFSGNQSNYAAALAIVMAVITMAIAYAVQLKSMKEQMK"
     gene            2586..3584
                     /locus_tag="Bbr_0419"
     CDS             2586..3584
                     /locus_tag="Bbr_0419"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|D6ZW62|3.A.1.1.48"
                     /protein_id="ABE95117.1"
                     /translation="MSAAASTRLTDAELKAQEKAARKAEKERQKRIAADEAAERRRSAR
                     AGFANVSNPRRSTLMTVLCAIFAVYCLFPFVYLVINATKTQADFTSTFGLGFGKSFALW
                     DNIVTVFTYQGGIFGRWLVNTLLYVVVGAGGATLLAIMGGYALAKFRFPGRKAVFAVII
                     GSISVPGIALAVPQFLLFAKLGLTNTPWAMIIPSLISPFGLYLMWIFSEQAVPTELLEA
                     ARVDGASEFRTFWTISLPLLAPGIVTTALFTIVATWNNYFLPLIMLKDADWYPLTIGLN
                     QWKDQASTAGGQAIQNLVITGSLITIIPLVIAFLCLQKYWQSGLAAGAVKE"
     gene            3752..5884
                     /gene="lacZ4"
                     /locus_tag="Bbr_0420"
     CDS             3752..5884
                     /gene="lacZ4"
                     /locus_tag="Bbr_0420"
                     /EC_number="3.2.1.23"
                     /codon_start=1
                     /transl_table=11
                     /product="GH42"
                     /protein_id="ABE95118.1"
                     /translation="MTTRRAFRWPSLLTESGRGIAFGGDYNPDQWPEETLDEDIRLMGE
                     AGVNVVSLAIFSWDKIEPVEGAFTFEWLDHVIDRLGKAGIAVDLASATATAPLWLYESH
                     PEVLPVDRYGHIVNAGSRQSWQPTSPVFKEYALRLCRKLAERYKDNPYVTAWHMGNEYG
                     WNNRYDYSDNALAAFRTWCEAKYGTIDALNEAWGTAFWSQHVNSFDEVLLPRHMGGDAM
                     VNPPQQLDYERFGNDMLLDFYKAERDAIEQICPGKPFTTNFMVSTDQCVMDYAKWAGEV
                     DFVSNDHYFHEGESHLDELACSDALMDSLALGKPWYVMEHSTSAVQWKPLNARKRAGEL
                     MRDSLAHVAMGADAICFFQWRQSVSGAEAFHSAMLPHAGADTKVFRGVCELGKALKTLS
                     DAGLQGTELERAGTAILFSAESEWATRSETLPSMKLNHWHDVRDWYRGFLDAGLRADVV
                     PLAYDWTDYKTIVLPTVLSLSDEDVRRIADFAKAGGTVIVGYATGLVDEYFHIGLGGYP
                     GAGNGLLRDMLGIRSEEFNILGEEAEGEPSEISLSNGLTTRLWQNDVTSVAADTTVLAS
                     YTGESAADWELERTPAITSHPYGNGTAIYVGCDLNRHDIAQLLKALGSRWRELSAQPTE
                     GGQTPTYPTTDPRILHTIRRSADGSTRFDFYLNRSNQPVAINGVEGKPIIAHRCETDAV
                     GYTLNRNAILIAKTSC"
     gene            5928..6983
                     /locus_tag="Bbr_0421"
     CDS             5928..6983
                     /locus_tag="Bbr_0421"
                     /codon_start=1
                     /transl_table=11
                     /product="DBD-Pfam|LacI,DBD-SUPERFAMILY|0036955"
                     /protein_id="ABE95119.1"
                     /translation="MSDEKTAKRRVTLRDVAQAAGVSLKTASNVINGSGRMTDETRAKV
                     ESVIKDLDYRVNVAARNLNRNHTGFITLAVPSLIPPYLAELANRTIEAARQRNYSVYVT
                     TYAEGSAKGARDLLKKFNSTVSDGMILSMSEVENISPDDLKVDFPLVIVGARTTWGIVD
                     HVTPDDVSAAAMAAGYLYERGSTRLAVIGARDVYDEDALLNAVEGNAQLRLRGIIEETR
                     RRGLSLDPQLIGNTDQDWTIGAGARVAQRLIDSGVPFDGVIALNDQLAIGALTALRTAG
                     YEVPAQVQVIGFDNNEEAPYLQIPLTTMDSRLDWTAPTAVNRILGRIDGSIIKPELLTT
                     ESQVIARASTR"
     gene            7179..9872
                     /gene="galA"
                     /locus_tag="Bbr_0422"
     CDS             7179..9872
                     /gene="galA"
                     /locus_tag="Bbr_0422"
                     /EC_number="3.2.1.89"
                     /codon_start=1
                     /transl_table=11
                     /product="GH53|CBM61"
                     /protein_id="ABE95120.1"
                     /translation="MRRNTALTRIMASSVAAIMLCAGGMFTANAAEEEPVKAAVSVKAI
                     QGLSDDFIGGMDVSSMLSLEESGVTFKNANDEVEDLFTLLKESGVNYVRLRVWNDPFTA
                     DGQGYGGGNVNADRALTMAKRATAAGLKVLVDFHYSDFWADPSKQQVPKAWKSFEGDVD
                     KTADTIYDYTKQTLTTFKQAGVDVGMVQVGNETTAKIAGISGWDGMSKVFSAGSKAIRE
                     VLPEAKVVIHFTNPEKAGTYATYAKQLSNHNVDYDVFASSYYPFWHGTTENLTSVLKNV
                     ASTYKKDVMVAETSWAYTLDDGDDDSNTVPSKVTANNLKKYDISPQGQADEIRAVAEAV
                     NNIGDNDGDGKNDGLGVFYWEPAWVPVGTGGKDNAELVDTWNKYGGGWATEAAGEYDPN
                     DAGLYWGGSGVDNQALFDFDGKALASLPTFKYIHTGAVTDHVFTKIDPVEITATDSDSI
                     DAIKAQLPSEVAAHYQDGVDETETVTWQSAALDWIRGAGTYTITGTTNAGHDVTATITV
                     TATPAKDYVTDGNFENAENDKNWTITGTGASITEDSGNAADGKRALKFWASDAYSFSAT
                     QTITGLEPGEYVLTAMSQGAAADNAAIADGVTLSATAGGKTTSDALELNGWVKFDTATV
                     PVTVGADGTATITITGNLPADAWGNVDKVSLVKKTETPVKPSTENLDKAVAEAGKINRD
                     ECTNESLAKLDQALAAADVLLAGSAYTEQDVNDVTKLVSDAIAGLAPKEVSSLTVTPSK
                     TTYQVGDVIDADHDLKVVGNYSAGMGNVTLSADQFTLDYDFSAPADAAKVTVTLKSNPN
                     VTETYTVAVTSRAEGGSGNGSDGAGNGGATINPDTGEGDKTNGANGGKITGVLSNTGSA
                     VTAVGLAVVVLGVAGGVSLALRRKRS"
ORIGIN
        1 atgcgcaaca ccaagaaggt catcgcggca acggcagccg tggccacgct cgtcggtctc
       61 gccgcctgcg gcagcagcaa cgacaacagc gtcaacaagg gtgacgccga caaggccgaa
      121 ctcgtgttct ggggctggga ttccggcaac tcgatgaagg aaatcctcgc tgacttcgag
      181 aaggccaacc ccggcatcac cgtcaagttc aacaacaccg gcaccgccga gaagacctcc
      241 accgcgctct ccaacgccat cgccgccggc aatggcgccc cggatgtcgt gatgctcgaa
      301 gatccgaccg tcacccagtt cgccgtcacc gatggcctcg tggatctgag ccggttcggt
      361 gccgacaagc tcgccgacga cttcgccgcc ggcccgtgga acaagctcca gtacaacaac
      421 aagccgtacg ctctgccgat tgattccggc cctgaaatgt tcttctacaa caaggcagtg
      481 ttcgacaagg ccggcgtgga cggcgagtcc atcaagactt gggacgacta ctacgaggcc
      541 gccaagaaga ttcgcgccat cggctcctac atcaccaacc ttgccggcac gtccaacgac
      601 taccagccct tcaccgccca gatctggcag gccggcgccc agccgtggaa ggtcgatggc
      661 gagaacatca ctatcaacat gaccaaggac gagggcatgc agcgctatat ccaattcgtc
      721 cagaagctca tcgacgaaga cctcgtggac accaagaccc cgaactggtc cgatgattgg
      781 aaccgcgagc tcaacgatgg caccctcgcc tccctgacca tcggcgcttg gatgccgatc
      841 aacctcatga ccggcgcccc cgatcaggcc ggcaactggc gcgtcgccca gctgccgcag
      901 tgggaggacg gcaaggaagt ctccgccgaa gacggtggct ccgcacttgc cgtcacctcg
      961 cagtccaaga accaggccgc tgcctacaag ctcgttgagt acatgactca tggcaagggc
     1021 gctcagacca tggccgacac cggtaccttc ccgtccctga agaagatcct gaagtccgac
     1081 tccttcaccg acccgaccac cgagtccaac aagaagacca acgactactt cggcggtcag
     1141 aacgtcaacg aagtcctttc cgccgcggct cagcgcccga ccgagaagtt ccagtacctg
     1201 ccgtacaacc cgtacgccca gaccgcttac ggcgacgaag tctccaaggc ctactccggc
     1261 gacatcaccc tggaggaagc actccagaac tacgccaaga agctggccga gcaaggcaag
     1321 cagcagggct acaacgtcac cgtcaagtga cacaatccga tctattgccg gtacatccgg
     1381 cactgaccaa caatcaaaac ctgcggctag gccactctcc ttccgcctag ccgcccgatc
     1441 tcccacagcg gggatgctcc ccagtgtccc cgctttccca tgccctcacc tgacgtgacc
     1501 gctccaatcg agcgaccccc ctgatagcgg gcgcagcaca gcaatccgta tcccaagaaa
     1561 gcaatcgatt atgtccgatc aaacaatggc cgcagcctcg cagccaacgg tgggaatcct
     1621 gcctgaggag gcggatctgc acacggccga ggcccgcgtc aacaagcata aggccgattg
     1681 gcgtggatgg aagttcatgt ggccgttcac ggtggtgttc gtgttcgtgt tcattattcc
     1741 gattgtgtac gccgtttaca tcagcttctt caagaagcag atgatcggcg gcacgaggtt
     1801 cgtcggggtc gagaactacg cgcgtctgct gcaggacggc cagttctggt cgtccgtggg
     1861 tcgtgtggcg ctgttcacct gcgtgcaggt gccgatcatg ctgttcctgt cggctgccat
     1921 ggccctcgcc ctggattcga tgaagctgca cggtgccaag ttcttccgca tcagcacgtt
     1981 cctgccctat gcggtgcccg cagtggtgtc cacgttggtg tggggcttcg tgtacggcgc
     2041 gaagtacggc ctggtgggct cgttcaacga cttcttcggc acgaacgtcg acgtgctgca
     2101 gccgggcgtg ctgcttgcct ccatcggcaa catcagcacg tgggagttca ccggctacaa
     2161 catgctgatc ttctactcgt cgctgtccac catcccgcac tccctgtacg aggccgcctc
     2221 catcgacggc gcctccgaat ggcagatcgt caagtccatc aagctgcccg agctgaaggg
     2281 ctcgctggcc atcacggtga tcttctcgat catcggcagc ttccagctgt tcaacgagcc
     2341 gagcatcttg cagaacatgg ttccgggcaa cgcgatcacc acgtactaca cgccgaacat
     2401 gtacgcgtac aacctgagct tctccggcaa ccagtcgaat tacgcggccg ctctggccat
     2461 cgtgatggcc gtcatcacca tggccatcgc ctacgccgtg cagctgaaga gcatgaagga
     2521 gcagatgaag tgacgacgac cgcccgtatt gccggattgg tttcgattgt gaaggagcgt
     2581 gcgtgatgag tgccgcagca tctacccgtc tgactgacgc cgaactgaag gcgcaggaga
     2641 aggccgccag gaaggccgag aaggaacgcc agaagcgcat cgccgccgat gaggcggccg
     2701 agcgcaggcg cagcgccagg gccggtttcg cgaacgtgag caacccgcgc cgttcgaccc
     2761 tgatgaccgt gctgtgcgcg atcttcgccg tgtactgcct gttcccgttc gtgtacctgg
     2821 tgatcaacgc caccaagacc caggccgact tcacctccac gttcggcctc ggcttcggca
     2881 agagcttcgc cctgtgggac aacatcgtca cggtgttcac ctaccagggc ggcatcttcg
     2941 gccgctggct ggtcaacacc ctgctctacg tggtcgtcgg cgccggcggc gccaccctcc
     3001 tggccatcat gggcggctac gcgctggcca agttccgctt cccgggccgc aaggccgtgt
     3061 tcgccgtgat catcggctcg atctccgtgc cgggcatcgc cctggccgtg ccgcagttcc
     3121 tcctgttcgc caagctgggc ctgaccaaca ccccgtgggc catgatcatc ccgtcgctga
     3181 tctccccgtt cggcctgtac ctgatgtgga tcttcagcga gcaggccgtg cccaccgagc
     3241 tcctggaggc cgcccgcgtg gacggcgcgt ccgagttccg cacgttctgg accatcagcc
     3301 tgccccttct ggcccccggt atcgtgacga ccgccctgtt cacgatcgtg gcgacgtgga
     3361 acaactactt cctgccgttg atcatgttga aggacgccga ctggtacccg ctgaccatcg
     3421 gtctgaacca gtggaaggac caggcttcga ccgcgggcgg ccaggccatc cagaacctgg
     3481 tgatcaccgg ctccctgatc acgatcatcc cgctggtcat cgcgttcctg tgcctgcaga
     3541 agtactggca gtccggcctc gccgcaggcg ccgtcaagga gtagttgcta ctccctctga
     3601 ctctcctcag agaggggagc tggagaaatg gggtcttggc ttccctctct gaggagagct
     3661 gtcgaacgca gtgagactga ggggagccaa agcccaaaac cggcaaacac agcaccggcc
     3721 atgagccgat acaataaagg atttgattaa tatgactact cgtagagcat ttaggtggcc
     3781 gtccctgctg acggaatccg gccgcggcat cgcgttcggc ggcgactaca acccggacca
     3841 gtggcccgag gagacgttgg acgaggatat ccgtctcatg ggtgaggccg gcgtgaacgt
     3901 cgtatcgctg gcaatcttca gctgggacaa gatcgagccg gtcgagggcg cgttcacgtt
     3961 cgagtggctc gaccatgtga tcgacaggct cggcaaagcc ggcatcgccg tggacttggc
     4021 ctccgctacc gccaccgcgc cgctgtggct gtacgaatcc catccagagg tgctgccggt
     4081 agaccggtat ggtcatatcg tcaacgcggg ctcacgccag tcgtggcagc ccacaagccc
     4141 ggtgttcaag gaatacgcgc tgcgcctgtg ccgcaaactt gctgaacgct acaaggacaa
     4201 cccgtatgtg accgcctggc acatgggcaa cgaatacggc tggaacaacc gctacgacta
     4261 ctccgacaac gccttggccg cgttccgcac gtggtgcgag gccaagtacg gtaccatcga
     4321 cgcgttgaac gaggcgtggg gcacggcctt ctggtcgcag cacgtgaaca gtttcgacga
     4381 ggtgttgctg ccgcgtcaca tgggcggcga tgccatggtc aacccgccgc agcagctcga
     4441 ctatgagcgg ttcggcaacg acatgctgct cgacttctac aaggccgaac gtgacgctat
     4501 cgagcagatc tgccccggca agccgttcac cacgaacttc atggtctcca ccgaccagtg
     4561 cgtcatggac tacgccaaat gggccggcga ggtggacttc gtgtccaacg accactactt
     4621 ccatgaaggc gaatcccact tggacgagct cgcctgctcg gacgcgctca tggactccct
     4681 cgcgctgggc aagccgtggt acgtgatgga gcactccacc tcagccgtgc agtggaagcc
     4741 gctcaacgcg cgcaaacggg ccggcgaact tatgcgcgac tccctggccc acgtggccat
     4801 gggcgccgac gccatctgct tcttccaatg gcggcagtcc gtgtccggcg ccgaggcgtt
     4861 ccactccgcc atgctgcccc acgcgggcgc cgacacgaag gtcttccgcg gcgtatgcga
     4921 gctcggcaag gcgctgaaga ctctctccga cgccgggctg cagggcactg agctcgagcg
     4981 tgccggcaca gcgatcctgt tcagcgcgga atccgaatgg gccacacgct ccgaaaccct
     5041 gcccagcatg aaactcaacc attggcacga cgttcgcgac tggtaccgcg gcttcctgga
     5101 tgccgggctg cgcgcggacg tggtgccgct cgcctacgac tggactgact acaaaaccat
     5161 cgtgctgccc accgtgctca gcctgtccga cgaagacgtt cgccgtatcg ccgacttcgc
     5221 gaaggccggc ggaaccgtca tcgtcggcta cgccactggc ctggtcgacg agtacttcca
     5281 catcgggctc ggcggatacc caggtgccgg caatggcctc ctacgcgaca tgctcggcat
     5341 ccgcagcgaa gaattcaaca tcctcggtga agaagccgaa ggcgagccca gcgaaattag
     5401 cctgtccaac ggtctgacga cccgcctgtg gcagaacgac gtgacttccg tagccgcgga
     5461 caccacagtg ctcgcctctt acacaggtga gtccgccgcc gactgggagc tggagcgcac
     5521 ccccgccatc accagccacc cctatggcaa cggtaccgcc atctacgtgg gctgcgacct
     5581 caaccgtcat gacattgccc agctgctcaa agcacttggc tcccgctggc gggagctgtc
     5641 ggcgcagccg actgagggtg gtcaaactcc aacctatccc accacagatc cccgcatcct
     5701 gcacaccatc cgccgatccg cagacggctc cacccgcttc gatttctacc tcaaccgctc
     5761 aaaccagccc gtcgccatca acggtgtgga aggcaagccc atcatcgccc accgttgcga
     5821 gacggatgcc gtcggatata cgctgaaccg taacgctatt cttatcgcta aaacgtcctg
     5881 ctagaccgcg ttagaatggc aatgttgtcc ggatggagga gcgcggcatg agcgacgaga
     5941 aaacagccaa gcgtcgagtg acgctacgcg atgtcgctca ggccgccggt gtatcgctca
     6001 aaactgcgtc gaacgtgatc aatggctccg gacgtatgac cgatgagacc cgtgccaagg
     6061 tcgagtcggt cattaaggac ctcgactacc gagtcaatgt ggccgcccgc aacctcaacc
     6121 gcaatcacac cggtttcatc acccttgccg tgccttcgct gattccgcca tatctggccg
     6181 agttggccaa ccgcaccatc gaggccgccc gccagcgcaa ctattccgta tacgtcacca
     6241 cgtatgcgga aggctccgcg aaaggcgcgc gcgatctgct gaagaagttc aactccacgg
     6301 tgtccgatgg catgatcctt tccatgagcg aggtggaaaa catttcgccc gatgatctga
     6361 aggttgattt tccgctggtc atcgttggcg cgcgtaccac gtggggcatt gtggatcacg
     6421 tgaccccaga cgatgtatcc gcagccgcca tggccgcagg ctacctgtat gagcgcggtt
     6481 ccaccagact tgcagtgatc ggtgcccgtg acgtttacga cgaagatgca ttgctgaatg
     6541 ccgtagaagg caacgcgcag ctgcgtctgc gcggcatcat cgaagagacc cgcaggcgtg
     6601 ggctctcctt ggatccgcag ctgattggca acaccgatca ggattggacc atcggagccg
     6661 gtgcccgtgt ggcccagcgg ctcattgatt ccggcgtgcc gttcgacggt gtgatcgccc
     6721 tgaacgatca gttggccatc ggcgcattga ccgctctgcg caccgctggt tatgaggtgc
     6781 ccgcgcaggt gcaggtcatc ggcttcgata acaacgagga agccccctac ctgcagattc
     6841 cgctgaccac catggattcc cgccttgact ggacggctcc cacggcagtg aatcgcatcc
     6901 tcggacgcat cgacggcagc atcatcaagc ccgaactgct caccaccgaa tcccaagtca
     6961 tcgcccgcgc ctccacgcgt tgaacgacat tgctgtaatg ctggtgttgc tgtactgggc
     7021 cgtacgaggc gatgatacac cggttgacca acgcggtata aagtgttaag gtgacaattg
     7081 cgtgatacac agctgtacca cgtggcgcat aaggaaagga agcgccaagc atcactgggc
     7141 gttcgttctg agcgttcacc attcaaagga gaaaaagcat gcgccgaaat accgcgctta
     7201 ctcgcattat ggcatccagc gtggccgcca taatgctctg cgcaggaggc atgttcactg
     7261 caaacgccgc cgaagaagaa ccagtcaaag ccgccgtctc ggtcaaggcc atccaaggct
     7321 taagcgatga tttcatcggt ggtatggacg tctcatccat gctctcgctg gaagaaagcg
     7381 gcgtcacgtt caagaacgcc aatgacgagg tcgaggattt gttcacgctg ctcaaggaat
     7441 ccggcgtgaa ctatgtgcgt ctgcgcgtgt ggaacgatcc gttcaccgca gacggccaag
     7501 gatatggcgg cggcaacgtc aacgccgatc gcgcactgac catggccaag cgagccacgg
     7561 cagcagggct gaaagtgctg gtcgacttcc attactccga tttctgggcc gaccccagca
     7621 agcagcaggt gcccaaggcg tggaaatcct ttgaaggcga cgtggacaaa accgccgaca
     7681 ccatatacga ctacaccaag cagacgctga ccacgttcaa acaagccggc gtagacgtcg
     7741 gcatggtgca ggtcggcaac gaaaccactg cgaaaatcgc cggcatctcc ggctgggacg
     7801 gcatgtccaa agtattctcc gcaggctcca aagccatacg cgaagtgctc cccgaagcca
     7861 aggtcgtcat tcatttcacc aacccggaga aagccggcac ctacgccact tatgccaaac
     7921 agttgagcaa ccacaatgtg gattacgatg tgttcgccag ctcctactac ccgttctggc
     7981 atggcaccac cgaaaacctc accagcgtgc tcaagaacgt ggcctccact tataagaaag
     8041 atgtgatggt ggcggaaacg tcgtgggcat acaccttgga tgatggtgac gacgattcca
     8101 acacagtgcc cagtaaagta accgccaata acctcaagaa atacgacatc agtccgcaag
     8161 gccaggccga tgagattcgc gcggtcgccg aggccgtgaa caatattggc gacaatgatg
     8221 gcgatggcaa aaacgacggc ctgggtgtgt tctactggga gcccgcatgg gtgcccgtgg
     8281 gcaccggcgg caaggataac gccgagctgg tggatacgtg gaacaagtac ggtggcggct
     8341 gggccactga agcggccggc gaatacgatc ccaatgacgc cggcctgtac tggggcggct
     8401 caggtgtcga taaccaagct ttgttcgatt tcgatggtaa ggcgctcgcc tctctgccga
     8461 cgttcaagta catccacacc ggtgccgtca ccgatcatgt gttcaccaag atagatccag
     8521 tggagattac cgcgactgac tcggattcca tcgacgcgat caaagcgcaa ttgccgagtg
     8581 aagtggctgc acactatcag gatggggtgg acgagaccga aaccgtgacc tggcaatccg
     8641 ctgcgcttga ctggattcgt ggcgcaggca catacaccat caccggcacc accaacgctg
     8701 gccacgacgt gaccgccacc atcaccgtca ccgccactcc cgccaaggat tacgtaacgg
     8761 acggcaactt cgagaacgct gaaaacgata agaactggac cattaccggc accggtgcgt
     8821 ccatcaccga agacagtggc aacgccgccg acggcaagcg cgcgctgaag ttttgggcat
     8881 ccgatgccta cagtttctcc gccacgcaga ccattaccgg actcgagcct ggcgaatacg
     8941 tactgaccgc catgagccaa ggcgcggcag cggacaacgc cgctattgcc gatggtgtga
     9001 ccctctccgc cacagcgggt ggcaagacca cgtccgatgc gctggaactc aacggttggg
     9061 ttaagttcga taccgccacc gtgcctgtca ctgtgggtgc tgatggcaca gcgaccatca
     9121 ccatcacggg caacctgcct gccgacgcat ggggcaatgt ggacaaggtc tcactcgtca
     9181 aaaagaccga aactccggtg aagccatcca cggagaacct ggacaaggcc gtggccgaag
     9241 ccgggaaaat caatcgcgat gagtgcacca acgagtcgct cgccaaactc gatcaggcgc
     9301 ttgccgccgc tgacgtgctg cttgccggca gcgcctacac cgagcaagac gtgaacgatg
     9361 tgactaagct tgtttccgat gccattgccg gcctcgcccc aaaggaggtc tccagcctga
     9421 ccgtcacgcc aagcaaaacc acctatcagg tgggcgatgt catcgatgcc gaccatgatc
     9481 tcaaggtcgt gggcaactat tccgcaggca tgggcaacgt gacgctttcc gccgaccagt
     9541 tcacgctcga ttacgatttc tccgctcccg ctgatgcggc gaaggttacc gtaacgctca
     9601 agtcgaatcc gaatgtcacc gaaacctata cggttgctgt tacctctcgg gccgaaggtg
     9661 gttccggcaa cggctcggac ggtgcgggta atggcggggc tactatcaat cccgatacgg
     9721 gcgagggcga taagaccaac ggtgcgaatg gcggcaagat cactggtgtg ctgagcaata
     9781 ccggtagcgc ggtgactgcc gtgggtcttg cggttgtcgt tctcggcgtg gccggcgggg
     9841 tctcgcttgc tttgcgtcgt aagcgctcct ga
//
