LOCUS       AE005672                5696 bp    DNA     linear   BCT 31-JAN-2014
DEFINITION  Streptococcus pneumoniae TIGR4, complete genome.
ACCESSION   AE005672
VERSION     AE005672.3
DBLINK      BioProject: PRJNA277
            BioSample: SAMN02604002
KEYWORDS    .
SOURCE      Streptococcus pneumoniae TIGR4
  ORGANISM  Streptococcus pneumoniae TIGR4
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5696)
  AUTHORS   Tettelin,H., Nelson,K.E., Paulsen,I.T., Eisen,J.A., Read,T.D.,
            Peterson,S., Heidelberg,J., DeBoy,R.T., Haft,D.H., Dodson,R.J.,
            Durkin,A.S., Gwinn,M., Kolonay,J.F., Nelson,W.C., Peterson,J.D.,
            Umayam,L.A., White,O., Salzberg,S.L., Lewis,M.R., Radune,D.,
            Holtzapple,E., Khouri,H., Wolf,A.M., Utterback,T.R., Hansen,C.L.,
            McDonald,L.A., Feldblyum,T.V., Angiuoli,S., Dickinson,T.,
            Hickey,E.K., Holt,I.E., Loftus,B.J., Yang,F., Smith,H.O.,
            Venter,J.C., Dougherty,B.A., Morrison,D.A., Hollingshead,S.K. and
            Fraser,C.M.
  TITLE     Complete genome sequence of a virulent isolate of Streptococcus
            pneumoniae
  JOURNAL   Science 293 (5529), 498-506 (2001)
   PUBMED   11463916
REFERENCE   2  (bases 1 to 5696)
  AUTHORS   Tettelin,H., Nelson,K.E., Paulsen,I.T., Eisen,J.A., Read,T.D.,
            Peterson,S., Heidelberg,J., DeBoy,R.T., Haft,D.H., Dodson,R.J.,
            Durkin,A.S., Gwinn,M., Kolonay,J.F., Nelson,W.C., Peterson,J.D.,
            Umayam,L.A., White,O., Lewis,M.R., Radune,D., Holtzapple,E.,
            Khouri,H., Wolf,A.M., Utterback,T.R., Hansen,C.L., McDonald,L.A.,
            Feldblyum,T.V., Angiuoli,S., Gesuwan,P., Hickey,E.K., Holt,I.E.,
            Loftus,B.J., Ujwal,M.L., Yang,F., Smith,H.O., Venter,J.C.,
            Dougherty,B.A., Morrison,D.A., Hollingshead,S.K. and Fraser,C.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-JUN-2001) The Institute for Genomic Research, 9712
            Medical Center Dr, Rockville, MD 20850, USA
REFERENCE   3  (bases 1 to 5696)
  AUTHORS   Shumway,M., Schobel,S., Koo,H., Dodson,R. and Tettelin,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-JAN-2006) The Institute for Genomic Research, 9712
            Medical Center Dr, Rockville, MD 20850, USA
  REMARK    Sequence update by submitter
REFERENCE   4  (bases 1 to 5696)
  AUTHORS   Tettelin,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JUL-2008) Institute for Genome Sciences, Department of
            Microbiology and Immunology, University of Maryland School of
            Medicine, HSF-II, Room S245, 20 Penn Street, Rockville, MD 21201,
            USA
  REMARK    Sequence update by submitter
COMMENT     On Jul 3, 2008 this sequence version replaced AE005672.2.
FEATURES             Location/Qualifiers
     source          1..5696
                     /organism="Streptococcus pneumoniae TIGR4"
                     /mol_type="genomic DNA"
                     /strain="TIGR4; ATCC BAA-334"
                     /db_xref="ATCC:BAA-334"
                     /db_xref="taxon:170187"
     gene            complement(1..888)
                     /gene="scrK"
                     /locus_tag="SP_1721"
     CDS             complement(1..888)
                     /gene="scrK"
                     /locus_tag="SP_1721"
                     /EC_number="2.7.1.4"
                     /note="identified by similarity to EGAD:21007; match to
                     protein family HMM PF00480"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase"
                     /protein_id="AAK75798.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKTI
                     EFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPMYF
                     TTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHYYVA
                     RHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYIAQAA
                     VNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAVAGNGS
                     ATLGNFVLAKEVSK"
     gene            complement(1037..2920)
                     /locus_tag="SP_1722"
     CDS             complement(1037..2920)
                     /locus_tag="SP_1722"
                     /note="identified by match to protein family HMM PF00358;
                     match to protein family HMM PF00367; match to protein
                     family HMM PF02378; match to protein family HMM TIGR00826;
                     match to protein family HMM TIGR00830; match to protein
                     family HMM TIGR01996"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|P08470|4.A.1.2.1"
                     /protein_id="AAK75799.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEVI
                     ENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQRA
                     IRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPGLVV
                     WSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGSVLPA
                     FIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYILIATK
                     AILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAAMTAQGA
                     ATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAGAIGGGLA
                     SILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYEDEVDATAA
                     AKRAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQGIVVKPSQGV
                     VYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFETKVAQGNKVKAGD
                     VLGTFDSNKIAAAGLDDTTMVIVTNTGDYASVAPVATGSVAKGDAVIEVKI"
     gene            complement(3046..3243)
                     /locus_tag="SP_1723"
     CDS             complement(3046..3243)
                     /locus_tag="SP_1723"
                     /note="identified by Glimmer2; putative"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AAK75800.1"
                     /translation="MQAFYVKKEEKLSKDYHKINTGNQSNFYENVKDNEIKYFLTKVSN
                     LFFKEFLMKQSKTINLKLAH"
     gene            3296..4750
                     /gene="scrB"
                     /locus_tag="SP_1724"
     CDS             3296..4750
                     /gene="scrB"
                     /locus_tag="SP_1724"
                     /EC_number="3.2.1.26"
                     /note="identified by similarity to EGAD:18627; match to
                     protein family HMM PF00251; match to protein family HMM
                     TIGR01322"
                     /codon_start=1
                     /transl_table=11
                     /product="GH32"
                     /protein_id="AAK75801.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGLL
                     NDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLIHFKETGIKVLPDTPLDSHG
                     AYSGSAMQFGDNLFLFYTGNVRDKNWIRHPYQIGALMDKEGKITKIDKILIDQPADSTD
                     HFRDPQIFNFQGQYYAIVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRTAYMM
                     ECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQLQNMD
                     YGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDDKLYQYP
                     VAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSINFDLVNGQ
                     VTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVFSGRVFPHA
                     DQNGILIKSGNPTGTYYELDYGRKTN"
     gene            4731..5696
                     /gene="scrR"
                     /locus_tag="SP_1725"
     CDS             4731..5696
                     /gene="scrR"
                     /locus_tag="SP_1725"
                     /note="identified by similarity to EGAD:41250; match to
                     protein family HMM PF00356; match to protein family HMM
                     PF00532"
                     /codon_start=1
                     /transl_table=11
                     /product="DBD-Pfam|LacI,DBD-SUPERFAMILY|0036955"
                     /protein_id="AAK75802.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMRELG
                     YKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDSEK
                     EREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAGGVL
                     AAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKEMEIK
                     NILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQLATIK
                     QPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
ORIGIN
        1 ttattttgaa acttcttttg caagaacaaa gttcccaagt gtggcagaac catttcctgc
       61 gactgctggc gtcacgatat agtcacgcac atctggtact ggtaggtaac cattaagaag
      121 agatgtaaat ttctcacgga cacggtccag catatgttgt tgagccatga cccctccacc
      181 aaagacaatc acgtctgggc ggaaagtcac tgtcgcatta accgcagctt gagcgatata
      241 gtaggcttga acatcccaaa cagggttgtt gagttcaata gtttccccac gtacacctgt
      301 acgagcttcc aaacttggac cagctgcata accttctaga catcccttat ggaaaggaca
      361 aacaccctta aactcttttt caatatccat tgggtgtcta gcaacataat aatgacccat
      421 ttcagggtga cccacaccac cgataaactc accacgttgg atgacgcctg caccgatacc
      481 tgtaccgatt gtgtagtaaa ccaagttttc gatacgacca ccagcattgt tacgggcaac
      541 catttcaccg taagcagagc tgtttacgtc tgttgtgaag tacattggca cgtttagggc
      601 gcgacgaagg gcaccaagca agtctacatt tgcccagttt ggttttggag tcgtcgtgat
      661 aaagccataa gtttttgagt ttttgtcaat atcaatcggc ccaaatgaac caactgcaag
      721 accagcaagg ttatcgaatt ttgagaagaa ctcaatggtt ttatcgattg tttcgattgg
      781 agttgttgtt ggaaattgtg ttttttctac aacgttaaag ttttcatcac cgacagcaca
      841 gacaaacttt gtaccgcccg cttccaagct tccatataat tttgtcatga taaacctctt
      901 gtttttattt tctttattat agcatacttc gaaagtctaa atgtctctat tttttagatt
      961 ttcctctgta aatcttacta tctaataaaa acgaacaaac atgtcatttg ttcgttttca
     1021 cattagagag gattgattag attttcactt cgatcacagc atccccctta gcaactgaac
     1081 ctgttgcgac tggagctact gaagcgtagt cacctgtatt tgtaacgata accattgttg
     1141 tatcatcaag tccagctgca gcgattttgt ttgagtcaaa tgttccaaga acatcgccag
     1201 ctttcacctt attaccttga gcaacttttg tttcaaaacc gtcaccgttc atagatacag
     1261 tatcaatacc aacatgaatc aaaacttcag caccatttct tgttttcaaa ccaaaagcgt
     1321 gccctgttgg aaaggcaatt gaaacttcag catcagctgg tgcatagacc acgccttggc
     1381 ttggtttcac aacgatacct tgtcccatag ctccacttga gaagactggg tcattgacat
     1441 cagcaagagc gacaacatca ccgacgatag gagttacaag tgtttcattt tgaagagctg
     1501 ctggcgcaac ttcttctttt tcttcagcca cttcagctcg ttttgcagct gcagttgcgt
     1561 ctacttcatc ttcgtaacca aacatgtaag taagagcaaa accaagggca aatgatacag
     1621 ctaccataag aaggtattgt ggaagttgtc cgttaccaac ataaagcatt gtaccaggga
     1681 tgatggtgat accattacca gtaccagcaa gtccaaggat agaagccaat ccaccaccga
     1741 ttgcaccagc aatcaatgaa aggaagaatg gtttacggaa gcgcaagttc accccgaaga
     1801 tagcaggctc tgtaatacct aggaaggcag aaagagcagc cgggaaagca agtgttttca
     1861 gttttggatt ttttgtttta acaccaaccg caacagtagc agcaccttga gctgtcatag
     1921 cagctgtgat gatagcgttg aatgggttag catggtcagc agcaagtaat tgcacttcaa
     1981 gcaagttgaa gatgtggtgc acacctgaca cgacgatcaa ttggtgaacc ccaccaatca
     2041 agaaaccacc aagaccaaat ggcatgctaa gaatcgcttt tgtagcaata aggatgtagt
     2101 tttcaacaac gtggaaaact ggtccaatga caaagagtcc aaggatagac atgaccaaaa
     2161 gtgtcacgaa tggtgttacc aagaggtcaa tgacatctgg aacaaccttg cggacagctt
     2221 tttcaaattt agctccgaca accccgatga tgaaggctgg aagaacggaa ccttgcaaac
     2281 caacaacagg gatgaaacca aagaagttca tcgctgttac ttcaccacct tgagcaactg
     2341 cccaagcgtt tggaagtgag ccagagacaa gcatcatacc aagaacgata ccaacggcag
     2401 gatttccacc aaatacacgg aaggttgacc acacaaccaa acctggcaag atgatgaagg
     2461 ctgtatctgt caagatttgt gtgtaagttg caaagtcacc tggaagtggc atttcaagag
     2521 cgttgaaaag accacgcaca cccatgaaga gacctgtcgc tacgataact gggatgattg
     2581 gaacgaaaac atcaccaaaa gtacggatag cacgttggaa ccagttccct tgtttagcaa
     2641 cttctgcttt catgtcatcc ttagatgatg ttggtaatcc aagtacaaca acttcatcgt
     2701 acattttgtt aactgtacct gtaccaaaga taatttggta ttgccctgag ttaaagaaag
     2761 caccttgaac tttttccaag ttctcaatca cttctttatt gattttctct tcatctttga
     2821 ccatgacacg tagacgagtc gcacagtggg caacactatt gacattttca cgtccgccca
     2881 aggcatcgat gacttttttt gcaatttcct gattgttcat ttgcaaaaat ctccttatat
     2941 aacattttgt tcttgtttga aagcgatttt attcgccctt acgactatta ttttatcatg
     3001 ttttaaaaat atgtcaagcg ttttgcagaa aaaaattcta tccacttagt gggcaagctt
     3061 tagattgatt gtttttgact gtttcatcag gaattccttg aaaaataagt ttgaaacctt
     3121 ggttaaaaag tattttattt cattatcttt cacattttcg taaaaatttg attgatttcc
     3181 tgtatttatt ttatgataat cctttgacag tttttcctct tttttaacat aaaaggcttg
     3241 cattttttat cgaaaacagt tactattaaa agtgataaga tttttggagg aatgaatgga
     3301 atggacaact gagcgtcgtt acagacttta tcaagattgg acgcaagaag aaattcaaca
     3361 tataaaggaa aatatggcac aatctccatg gcatactcat taccatgttg agccaaaaac
     3421 aggacttctc aacgacccaa atggcttttc ttactttgat ggcaagtgga tcctctttta
     3481 ccagaatttt ccttttggtg cagcccacgg tttaaaatct tgggcacagc tagaaagtga
     3541 tgatttgatt cactttaaag aaactggaat caaagtttta ccagatactc cattagatag
     3601 ccacggtgcc tactctggtt ctgccatgca atttggcgat aacttattcc tattttatac
     3661 aggaaatgtt cgcgataaaa actggatccg tcacccatac cagatcggtg ctttgatgga
     3721 caaggagggt aagattacaa agattgacaa gatcttgatt gaccagccag cagactctac
     3781 tgaccacttc cgcgatccac aaatttttaa ctttcagggt caatattatg ccattgtcgg
     3841 cggacaagac ttggagaaaa aaggtttcgt tcgtctctac aaggctgtca ataacgacta
     3901 cacaaactgg caagcagttg gcgaccttga ctttgctaac gaccgtactg cctacatgat
     3961 ggaatgtcct aatttggtct ttgtagagga acaacctgtc cttctctact gtccacaagg
     4021 attggataag aaagttctag actacgataa tatctttcca aatatgtata agatcggggc
     4081 ttcctttgac cctaaaaatg ccaaaatggt agatgtgtct caacttcaaa acatggatta
     4141 cggtttcgaa gcctatgcaa ctcaagcctt caacgctcct gatgggcgtg ctctagcagt
     4201 tagctggctt ggtttgccag atgtttctta cccatctgac cgttttgacc accaaggaac
     4261 cttctctttg gtcaaggaac tcactatcaa agacgacaag ctctaccagt atccagtcgc
     4321 tgctattaag gaccttcgtg cttctgaaga agccttctca aaccgttccc aaaccaagaa
     4381 cacttacgaa cttgaactca acttggaagc taatagccag agcgagattg tcttacttgc
     4441 tgataaagaa ggtaagggac tttcaatcaa ctttgacctt gtaaacggtc aagtaacagt
     4501 ggatcgtagc caggctggag aacagtatgc ccaagaattt gggacaactc gttcttgccc
     4561 tatcgagaat caggctacta ctgctacaat cttcatcgat aactctgtct ttgaaatttt
     4621 catcaataaa ggagaaaaag tattttctgg tcgtgtcttc ccacatgcgg accaaaatgg
     4681 tatcctgatt aaatctggaa acccaactgg aacttactat gaattagatt atggtcgcaa
     4741 aactaactga tgtcgccaaa cttgcaggcg tcagtcctac taccgtttct cgggttatca
     4801 ataaaaaagg gtatctatct gagaaaacca tccaaaaagt caatgaagcc atgcgagaat
     4861 tgggctataa acccaacaac ctggctcgta gtctgcaagg aaaatcagct aagttaatcg
     4921 gcttgatttt ccccaatatt tccaatgttt tctatgcaga attgattgat aaattggaac
     4981 accaactctt caaaaatggt tacaagacca tcatctgcaa cagtgaacat gattctgaga
     5041 aggaacgcga atacatcgaa atgttggaag ccaatcaggt ggacggcatc atttctggta
     5101 gtcacaacct aggaatcgaa gactacaatc gtgtgacagc gccgattatt tcctttgacc
     5161 gaaacctatc gccagacatc cctgtcgtct cctctgacaa ctatgctggt ggggttcttg
     5221 ctgcccaaac cttggtcaag acaggtgccc agtctatcat catgattaca gggaatgaca
     5281 attctaattc gccaaccgga ctgcgccacg ctggttttgc atccgtactc ccaaaagctc
     5341 ctattatcaa tgtttccagt gacttttctc ccgtcagaaa agaaatggaa atcaagaata
     5401 tcttgacccg ggaaaaacca gatgccattt ttgcttcgga tgatttgaca gctattctgg
     5461 tcattaaaat cgctcaagaa ttgggcattt ctgtcccaaa agagctcaag gtcatcggct
     5521 atgatgggac ctactttatc gaaaattact accctcaatt ggctactatc aagcaacctt
     5581 tggaagagat tgcttgtctc actattgatc ttctcttgca aaagattgaa ggcaaggaag
     5641 tcgccacaac tggttacttc ttaccagtta cgctattacc aggaaaaagt atttaa
//
