LOCUS       CP001515               13714 bp    DNA     linear   BCT 30-JAN-2014
DEFINITION  Bifidobacterium animalis subsp. lactis Bl-04, complete genome.
ACCESSION   CP001515
VERSION     CP001515.1
DBLINK      BioProject: PRJNA32897
            BioSample: SAMN02603172
KEYWORDS    .
SOURCE      Bifidobacterium animalis subsp. lactis Bl-04
  ORGANISM  Bifidobacterium animalis subsp. lactis Bl-04
            Bacteria; Actinobacteria; Bifidobacteriales; Bifidobacteriaceae;
            Bifidobacterium.
REFERENCE   1  (bases 1 to 13714)
  AUTHORS   Barrangou,R., Briczinski,E.P., Traeger,L.L., Loquasto,J.R.,
            Richards,M., Horvath,P., Coute-Monvoisin,A.C., Leyer,G.,
            Rendulic,S., Steele,J.L., Broadbent,J.R., Oberg,T., Dudley,E.G.,
            Schuster,S., Romero,D.A. and Roberts,R.F.
  TITLE     Comparison of the complete genome sequences of Bifidobacterium
            animalis subsp. lactis DSM 10140 and Bl-04
  JOURNAL   J. Bacteriol. 191 (13), 4144-4151 (2009)
   PUBMED   19376856
REFERENCE   2  (bases 1 to 13714)
  AUTHORS   Barrangou,R., Briczinski,E.P., Traeger,L.L., Loquasto,J.R.,
            Richards,M., Horvath,P., Coute-Monvoisin,A.-C., Leyer,G.,
            Rendulic,S., Steele,J.L., Broadbent,J.R., Oberg,T., Dudley,E.G.,
            Schuster,S., Romero,D.A. and Roberts,R.F.
  TITLE     Direct Submission
  JOURNAL   Submitted (17-MAR-2009) Danisco USA Inc, 3329 Agriculture Drive,
            Madison, WI 53716, USA
COMMENT     Genome was manually curated based on annotation generated by the
            NCBI Prokaryotic Genomes Automatic Annotation Pipeline Group.
            Information about the Pipeline can be found here:
            http://www.ncbi.nlm.nih.gov/genomes/static/Pipeline.html.
FEATURES             Location/Qualifiers
     source          1..13714
                     /organism="Bifidobacterium animalis subsp. lactis Bl-04"
                     /mol_type="genomic DNA"
                     /strain="Bl-04; ATCC SD5219"
                     /sub_species="lactis"
                     /culture_collection="ATCC:SD5219"
                     /db_xref="taxon:580050"
     gene            complement(1..1836)
                     /locus_tag="Balac_1593"
     CDS             complement(1..1836)
                     /locus_tag="Balac_1593"
                     /note="COG0366 Glycosidases"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q05839|8.A.9.1.1"
                     /protein_id="ACS46928.1"
                     /translation="MTTMNRPVLPDSVRTNGATPNPWWANAVVYQIYPRSFQDSNGDGI
                     GDLKGITSRLDYIADLGVDVIWLSPVYQSPQDDNGYDISDYEAIDPIFGTMDDMDELLA
                     EAHKRGIKVIMDLVVNHTSDEHAWFQESRDPNSSKADWYWWRPAKPGMEPGAPGAEPNE
                     WGSYFGGSAWQYDAKRGEYFLHQYSKKQPDLNWENPQVRKAVYAMMNWWMDKGIDGFRM
                     DVITQISKVVDKNGRLPGEAGSEIDDYPAGPEGYSSPYPFSSDGPRIDEFLQEMRREVF
                     EKRGGYMNVGEAPGVDAARNEYITDPDHKELDMLFLFDHVGIDQGDSKWDIVKFDVRHL
                     REQLKAQQEAVHDRGWASLFTCNHDQPRVVTRWGDDSNEENRVHSAKAFGMLIHLHRGT
                     PYIYQGEELGMTGAHFTELSQYRDLESINAYRQRVEEAKVQSGESMMDSLALFGRDNAR
                     TPMQWDGSKYAGFTAADAKTEPWLSVNPNHVEINAAAQFDDPDSVYAFYKKLVNLRHNS
                     AVVSAGEWALVDDDDEQVYAFTRTLTNADGTAERMLVAINLTGRHAALPKPVADLLADG
                     VSEDRIILSTYDAIHSAKSLANGELAGWEGVVVEL"
     gene            complement(1915..2043)
                     /locus_tag="Balac_1594"
     CDS             complement(1915..2043)
                     /locus_tag="Balac_1594"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ACS46929.1"
                     /translation="MAFLAETSVKYAAQTPYMVDFAKIPVHVTAELLSHTPVRILR"
     gene            2637..3593
                     /locus_tag="Balac_1595"
     CDS             2637..3593
                     /locus_tag="Balac_1595"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="ACS46930.1"
                     /translation="MKIDSQIERLLDESQNAHRCAVTTDVNLRRKLRRRCESGELTMPY
                     PQLFARKETWDALNPREKKRHVILALAMVRPDWIFCAQSAACLYGIEQSYQIHDNPMIH
                     IASTHESGIYRARRSDAVIHRVYTPNPQYNVINGAKVTTLPCTIYQCALVLPFEQILPL
                     ADSAVRSGMALDDLRQFPVHSATEALAIGNVLEYTDPRSENGGETLARSRFIERGLMIP
                     QLQKEFPNPQNPEYPFRVDFIWILPNGRMIVAEYDGMTKYGNDRKTIANHVHREKLRDE
                     ALRQHGVTAIIHFDYEDLLNPNELIARLVAAGVPYRR"
     gene            complement(4034..5644)
                     /locus_tag="Balac_1596"
     CDS             complement(4034..5644)
                     /locus_tag="Balac_1596"
                     /note="COG3345 Alpha-galactosidase"
                     /codon_start=1
                     /transl_table=11
                     /product="GH36"
                     /protein_id="ACS46931.1"
                     /translation="MRPAWVERFCDIPERTQLVLWKSAKAWHVMIPVFCHGMRVDIRGD
                     GRGDNDLLLDVSTNQVGHVQLQGPLLVHRQSDRKVEDPYELIRGCAEWVMLQNGGLGRL
                     WKQTLPESLRGFGWCTWDSLGTNVSEQAIIAKMEEFAAKHVPVSWVLIDDGWSQVENGK
                     LTGFDADTTRFPQGLSHTIDVLKHDFGVRYVGVWQAFQGYWRGVDVDALAGKPESDDDW
                     REYYKQGYSDGDARVEDPKLLVSRSAFETLPNGMAIPTANPECAALFWRTWNTHLDAAG
                     IDFVKVDSQGTLPVLTRGLESYASLGVRHDAVEYATNWIRHEDDNGDWEYAHLAVIHCM
                     GMTPENYWQRCAEGVARTSDDFFPNIPESLAEHAIENAYCSLLIGCLCYCDWDMFWTRH
                     PHARTHMLLRWISGGPIYCSDKLGETDSAPLAPLFDADGNLTHPDGVGVPVLDSLLADP
                     VHGDVPLGIRNTFRGDEVLLFVGLNADAPQTAHIRATESPLTVFDPQTGERVHLSVGED
                     LALTLHYGECELRILQTLT"
     gene            complement(6879..7784)
                     /locus_tag="Balac_1597"
     CDS             complement(6879..7784)
                     /locus_tag="Balac_1597"
                     /note="COG0395 ABC-type sugar transport system, permease
                     component"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q00751|3.A.1.1.28"
                     /protein_id="ACS46932.1"
                     /translation="MTTATANTMSQQSAQQSATMNTAPAKAEKFRKDRRINWWLTAVVA
                     VFSLTILVPLYFTVVTALKTPAEAGTFSLPTSWQWGNFAAASAKVDYPRAALNSAIITV
                     LAVSLTLVTNTFVAYAIARNMDKRFFRFLYYFFIAAMFVPFPVVMLPLAKQMGSWHLDN
                     QAGLIVLYVILGLGTNLFIATGFIRSIPVSLEEAARIDGAGTWRIFWKIIFPLMGPINA
                     TIAIMTALWAWNDFLLPLIILTDQSNQTIPLAQYVFSSQFATNYPQAFASYLMAMAPVL
                     VVYIFAQKWVVGGVMRGAVK"
     gene            complement(7789..8781)
                     /locus_tag="Balac_1598"
     CDS             complement(7789..8781)
                     /locus_tag="Balac_1598"
                     /note="COG1175 ABC-type sugar transport systems, permease
                     components"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q00750|3.A.1.1.28"
                     /protein_id="ACS46933.1"
                     /translation="MTSLANADQQARAMEDVLANDIDTHHSRTPAGKPPRKRRVSAFSR
                     RKVDHAYYWMAVPAAVIFAVFLYVPFVRGIMYSFTNSQGYGSCNWIGFQNYFALFRDER
                     VGHAYLFTFLIAIAITVLINVIALFLSVALNGKIACKNGFRAIYFIPYTLAVLVIGYVF
                     KYIFMQPLPELGKALGIGWLSESLLTSERYAWIPIVFLAVWQGVAYSVLIYLAGLQTVD
                     SEVYEAAAIDGVNAWQKFWKITFPLIGPFFTINLVLTMKNALGTFDQVVALTDGGPNSK
                     TETVTYLIWKGGLTGGEYAYQTANAVLFFIVLAIIAFIQLKFFGSKEKV"
     gene            complement(8815..10128)
                     /locus_tag="Balac_1599"
     CDS             complement(8815..10128)
                     /locus_tag="Balac_1599"
                     /note="COG1653 ABC-type sugar transport system, periplasmic
                     component"
                     /codon_start=1
                     /transl_table=11
                     /product="STP|SBP_bac_1"
                     /protein_id="ACS46934.1"
                     /translation="MDKGVRMKFATRMRRSAMRRMLRGIGAAVCALAVGVGAAGCGNSA
                     GSGQVTLDFFQFKAEAADWFKQAAQEFEKENPDIRININNSANAQTDLRTRFVKDRVPD
                     VITFNGDYSFGTFAASGVFHDFTDDPLVSELNEGMVNIAKNLVQTSDPAKKRLYGLPFA
                     GNASGYIYNKDLFRKVGLDPDNPPQTWDEFIAMLKKFRDAGINPVQATLADAWTTQAPL
                     ASLAGTLVPESEYAALKSGDTTFKQIWTEPIEKEIELFKYADSEKGVTYQQGTQNFAKG
                     TAAIIPLGTYAIPQITMVNKDIDLGFAQMPATNDASKQILTAGDDVILTMGANSRHKEQ
                     SMRFIRFLMSKKQLENYADAQSAITPLKETYFGNKALEPVRPFFESNRVADFCDHYIPS
                     SINIGGYLQSAIMSGNVNQFIDSMQNEWNKVQARDFRK"
     gene            10259..11467
                     /locus_tag="Balac_1600"
     CDS             10259..11467
                     /locus_tag="Balac_1600"
                     /note="COG1940 Transcriptional regulator/sugar kinase"
                     /codon_start=1
                     /transl_table=11
                     /product="NagC-type Transcriptional regulator"
                     /protein_id="ACS46935.1"
                     /translation="METNSDSLDFPRWFSRSDATHNVARGIMQYGPIARTPLAQIFNLS
                     QGALSRITSDLIYDGVIEEMPAGSTQAGRLPQGFDLRESSERRGRPQTALRIREDSHAF
                     VGVNIHDGAITVSEVNTMCRPIGSDITETVSNTAPQAVVEQITRMVRELVAASPDAPAP
                     TALGLSLGGHVEDDRYVTFAPFLYWDSSVDLGGMLQRDTGIPTKVFNDLDSVLLHECWF
                     GDAIGVPRFAVITMGAGVGYSISDHGDPIDNPDKSYGLAGHVLIDPEGPRCSSGHIGCS
                     QCLTSDSIAEEYSGIMGRVTTFEEFSHDLRANRPQARRLAERTCYRLGVLVATVSNLAM
                     PSRVLVSGESSFIAKKNREFIRKGIDAYRHSQAAPVEFSIPRFSWRLWSDSAAARAIAT
                     YIS"
     gene            complement(11492..13714)
                     /locus_tag="Balac_1601"
     CDS             complement(11492..13714)
                     /locus_tag="Balac_1601"
                     /note="COG3345 Alpha-galactosidase"
                     /codon_start=1
                     /transl_table=11
                     /product="GH36"
                     /protein_id="ACS46936.1"
                     /translation="MTRISEFNATTHAGEALHVVSMENHDADSAFALAFVADELPRVVH
                     WGRPLTQPRTLVSAVDALRPQRVSGALDETTWPSVLPTQAEAWTGEPRFVVRRDGVELF
                     CRFVVTDIAVGDAGVAVTASDAEQGVEIIWTCEMRDSGLVRQRADVRNLGAGSLEIGKV
                     ELGFPVPADMTELLTTTGHHLRERSPQRQPLTIGRFQKASMVGRPDFDASLLLNAGRPG
                     FGFTHGDVYAVHVAWSGNSLMAAERLPYTTGVIGGAEVLAGGEITLHDAADSYTTPWLY
                     GSFGEGLNEVAARFHADLRATHARWRAEHGIADKPRPVILNTWEAVYFEHDYDTLVRLA
                     DKAAASGVERFVVDDGWFGDRRGDTAGLGDWRISQDVWPDGEHSLKALADYVHAKGMEF
                     GLWFEPEMVNPDSAMYREHSDWVLMPTAHRLPMQGRNQQVVDLTNPQAYAYVYGCMDSL
                     VGELGIDYIKWDHNKYVTEAVSPRTGSCAVHGQTLAVYRMFHDLKTSHPGLEIESCSSG
                     GGRVDMGILELADRIWASDCVDPVERADIQRYTSLLVPPEMIGEHVGASPAHSTHRATS
                     QEMRMAMAFFGHLGIEWNLLKEPQHDLDLLGEWVHAYKEHRVDFEHGVAVHDDAADPTV
                     RVDGVISADGARAVYRFTQLTTSQTYPAAPIALPGLDAQATYRVRPLALNMASGEPFGE
                     IGNGQSELGWWNANGVEMTGEALASYGLRPPSIHPANAVLFSVTRV"
ORIGIN
        1 tcagagttcg acgacgacgc cctcccagcc ggcgagctcg ccgtttgcca aggatttcgc
       61 ggagtggatg gcatcgtatg tgctcaggat gatccggtct tcactcacgc cgtcggcgag
      121 cagatccgcg accggcttcg gcagcgcggc atgccgacca gtcagattga tcgccaccag
      181 catgcgctcc gccgtgccgt ccgcgttcgt cagcgtgcgc gtgaacgcgt agacctgctc
      241 gtcatcgtcg tcgacgagcg cccattcccc ggccgacaca acggcactgt tatgccgcag
      301 attgacaagc ttcttataga atgcgtagac cgaatccggg tcgtcgaact gtgcggcggc
      361 attgatctcc acatggttcg ggttcaccga cagccatggc tcggtcttgg cgtcagccgc
      421 ggtgaatccc gcatatttcg aaccatccca ctgcattggc gtgcgcgcat tgtcgcgacc
      481 gaacagcgcg agcgaatcca tcatggactc gccggactgc accttcgcct cttcgacgcg
      541 ctggcggtat gcgttgatcg actcgagatc gcggtactgg ctgagttccg tgaaatgtgc
      601 gcccgtcatg ccgagctcct cgccctggta gatgtacggg gtaccgcgat gcagatggat
      661 gagcatgccg aaggccttcg ccgaatgcac acggttctcc tcattcgaat cgtcgcccca
      721 gcgagtgacc acgcgcggct ggtcgtggtt gcaggtgaac agactcgccc acccgcggtc
      781 gtgcacggcc tcctgctgcg ccttgagctg ctcgcgcagg tggcgcacat cgaacttgac
      841 gatgtcccac ttcgaatcgc cctggtcaat gcccacatgg tcgaacagga atagcatgtc
      901 gagttccttg tggtctggat cggtgatgta ctcgttacgc gcagcgtcca cacccggcgc
      961 ctcgccgacg ttcatatagc caccgcgctt ctcgaacacc tcacgacgca tctcctgcag
     1021 gaactcatcg atgcgcgggc cgtcggagga gaacgggtac gggctcgagt acccttctgg
     1081 gccggccggg tagtcatcga tctcggaacc cgcttcgccc ggaagacggc cgttcttgtc
     1141 gaccaccttg gagatctgcg tgatcacgtc catacggaag ccgtcgatgc ccttatccat
     1201 ccaccagttc atcatggcgt agacggcctt acgcacctga ggattctccc aattgaggtc
     1261 cggctgcttc ttcgaatact ggtggaggaa gtactcgcca cgcttggcgt catactgcca
     1321 tgcggaacca ccgaagtagg agccccattc gttcggctcg gcgcccggtg cccccggttc
     1381 catgcccggt ttggcggggc gccaccagta ccagtccgct ttgctggaat tggggtcgcg
     1441 agactcctgg aaccatgcat gctcgtcgga ggtgtgattg accacgaggt ccatgatcac
     1501 cttgatgccg cgcttgtgcg cttcggcgag cagctcgtcc atgtcatcca tcgtgccgaa
     1561 gatcgggtcg atggcctcat agtcggaaat gtcatagcca ttgtcgtcct gcggcgactg
     1621 atagaccggg ctcagccaga tcacgtccac gccgagatcg gcaatgtaat cgagtcggct
     1681 cgtgatgccc ttgagatcgc cgatgccgtc gccgttagaa tcctggaaac tccgcggata
     1741 gatctggtac accaccgcgt tcgcccacca cgggttcggc gtcgcgccgt tcgtacgcac
     1801 ggaatcggga agcacaggcc tattcattgt ggtcatggaa gctcctttgc ctttgaataa
     1861 caaccgccaa cactatagag atggctccat agtaggcacc cctgaattaa ttgcctagcg
     1921 tagtatgcgg acgggcgtgt gggaaagtaa ttccgcggtc acatgcacgg gaatcttcgc
     1981 aaaatcgacc atatacggcg tttgcgcggc atactttacg gaagtctccg caaggaatgc
     2041 catgctggag cctctttgcg gtcggtcatg cggaagcatc cgtaaaccat gccgcggcgg
     2101 agtctgcaaa tgatgtatct tacggaacgc tccgagaacc atgccagcaa aagacgtttt
     2161 tgcggtccgt ctcaaggaaa cttccgaaaa ccatgccaca aagaagcgct attgcggcgc
     2221 atcttacgga agcttccgaa aaacacggcg caaacgggta cccctgcggc atatctcacg
     2281 gaagactccg cacaatgaac cgcgaagaga acaatctgcg gatcagtttg cggaagactc
     2341 cgagaaacaa accgttttga gaccaccgcg cggtcggtca tgcggaaggt tccgagtaat
     2401 ggggcgccac agcggcaatc tgtggcacgt cgtacggaag gttccgagaa acacaccaag
     2461 gaggaatcca gaaatggcat atcttacgga agcttccgaa aaacaagcca caaacaaagc
     2521 gcaaaacagc acttccaagc gcccataggc gctgaatacg gtggacaacg gcgaagttat
     2581 ccacaaattc caaatcggga ttgcacgaca ttcgacactc tcctaccgtc gaaagcatga
     2641 agatagattc gcaaatcgag cgactcctcg acgagtccca gaacgcacac cgatgcgcgg
     2701 tgacgaccga cgtcaacctg cgccgcaaac tacgccgcag atgcgaaagc ggcgaattga
     2761 ccatgccata tccgcaactg tttgcgcgga aggaaacttg ggatgcgctc aatccgcgcg
     2821 agaaaaagag acatgtcata ctcgccctgg caatggtgcg ccccgactgg attttctgcg
     2881 cacagagcgc ggcttgcctg tacggcatcg agcagtcgta ccagattcac gacaatccga
     2941 tgatccacat cgcatccaca cacgaaagcg gcatataccg ggccaggcgg agtgatgccg
     3001 tcatacaccg cgtgtacacg ccaaatccgc aatacaacgt gatcaatgga gccaaggtca
     3061 ccacactgcc gtgcacaatc taccaatgcg cgctcgtgct gccgttcgaa cagatactgc
     3121 cgctcgcaga ttccgcagta cgcagcggta tggcgctcga cgatctgcga cagttccccg
     3181 ttcacagcgc gaccgaggca ctcgcgatcg gcaacgtgct cgaatacacc gacccgcgca
     3241 gtgagaacgg cggtgagacg ctcgcaagaa gccgattcat cgaacgcggg ctcatgattc
     3301 cgcagctgca gaaggagttc ccgaatccgc agaacccgga atacccgttc cgcgttgatt
     3361 tcatttggat tctgccgaat ggacgcatga tcgtcgccga atacgacggc atgacgaaat
     3421 acggcaatga ccgcaagacc atcgcaaacc acgtgcaccg ggagaaactg cgcgacgaag
     3481 cgctgcggca acacggcgtc accgcgatca tccatttcga ttatgaggat ttgctcaatc
     3541 ccaacgaact cattgccagg ctcgtcgccg ccggtgtgcc gtaccgccgc tgagcatgca
     3601 gcggatctgg tcgcggcatg gtatgcggaa gattctgaga accgtgccgc aaacgtagac
     3661 ttttgcggtc gatcatgcgg aagactccgt aaaccgtgcc tcaaaaggca tcccgcgcgg
     3721 cacgtcttac gggaagttcc gagaaaccgg ccatcggaca gtctggaaac tgcacttcct
     3781 aagggcgcct ccatgaaact ggctgcgaaa ggagcttatg cggcatggct tacggaaggt
     3841 tccgagagtc gtaccgcaaa tggagacttc cgcggtcagt cttacggaag gttccgtgaa
     3901 agcgactata ttcaggtcac tttgcggtcg aatatacgga cgactccgaa aaacagacca
     3961 cgaaacgggg tctgtgcggt acagcttacg gaagactccg agagctgtgc cgaaaataca
     4021 cgcgggcgcc ggattatgtg agagtctgca atatgcgcag ctcgcactcg ccataatgca
     4081 gcgtgagcgc gaggtcttcg ccgacgctca gatgcacgcg ctcgccggtc tgcggatcga
     4141 acaccgtgag aggagattcc gtcgcgcgaa tgtgggcggt ctgcggggca tcggcgttca
     4201 atccgacgaa cagcagcacc tcgtcgccgc ggaacgtatt gcgaatgccg agcggaacgt
     4261 caccatgcac cgggtctgcg agcagactgt cgagcaccgg cacgccgacg ccgtccggat
     4321 gcgtgagatt gccgtcagca tcgaacagcg gggcgagagg agcggaatcg gtctcgccaa
     4381 gcttgtcgga acagtagatc gggccaccgc ttatccagcg caacagcata tgcgtgcgcg
     4441 cgtgcgggtg gcgggtccag aacatatccc agtcgcagta gcagagacag cctatgagca
     4501 gcgaacagta cgcgttctcg atggcatgct cggcgagcga ttcgggaatg ttcgggaaga
     4561 agtcgtcgct cgtacgggcg actccctcag cacagcgctg ccaatagttc tcgggagtca
     4621 tgcccatgca gtggatcacg gcgagatgcg cgtattccca atcaccattg tcatcttcgt
     4681 gacgtatcca gttggtggcg tattccacgg catcatggcg aacgcctaga gacgcatagg
     4741 attccaggcc gcgcgtgagc acaggaagtg tgccctgcga atccaccttc acgaagtcga
     4801 tgccggcggc gtccaagtgc gtgttccatg tacgccagaa cagcgctgca cactccggat
     4861 tcgcagtggg gattgccatg ccattgggca gtgtttcgaa cgcggatcga ctcacgagga
     4921 gcttggggtc ctcaacgcgc gcgtccccat ccgaataccc ctgcttgtag tactcgcgcc
     4981 aatcatcgtc ggattcgggc ttgccggcga gcgcgtccac atccacgcca cgccaatacc
     5041 cttggaacgc ctgccatacg ccgacgtacc gcacgccgaa gtcgtgtttg agcacgtcaa
     5101 tggtgtgcga gagtccctgc gggaagcgcg ttgtgtcggc gtcaaaaccg gttagcttac
     5161 cgttctcgac ttgagaccaa ccgtcgtcta tgagcaccca cgaaacgggc acgtgtttgg
     5221 cggcgaactc ctccattttg gcgataatgg cctgctcgct cacgttcgtg ccgagcgagt
     5281 cccaggtgca ccagccaaaa ccgcgcaacg attccggcag agtctgcttc cacaatctcc
     5341 ccaagccacc gttctgcaac atgacccact ccgcgcatcc ccgaatcagc tcgtaaggat
     5401 cctcgacttt ccgatcgctt tgccgatgga cgagcagtgg cccctgcaat tgcacatggc
     5461 caacctgatt cgtggagaca tcgagcagca agtcattgtc gcctcgccca tcgccgcgaa
     5521 tgtcaacgcg catcccgtga cagaacaccg gtatcatcac atgccacgcc ttcgccgatt
     5581 tccacagcac cagctgggtg cgctccggta tgtcacagaa acgctcgacc catgccggcc
     5641 gcatccacca ttccttgtgc tggtaaaggc acagaatcgg ccccactggc ttcgatctgc
     5701 ctaattgcag ccgtacggac accgaccgcc cggccagcaa tgtgggacgc tcgagaatcg
     5761 gattggattc cggaagctgc gcacttatct ccgtcaccgt tgcgctacgc agtgtgcgcc
     5821 acggtattct gtgttcgctc accgagtccg ggggcagttc gacttcgccg tgctcatcga
     5881 acggcccgca ttcggtatgc gccaccactg atctcaccgt tatcatgggc gtctccctcc
     5941 tgccgttctt cgttgacctg cattggttcc cgccacaata accggctttg gctgccgttt
     6001 ccagcccgcc acgccgagcg tcattacccc ctcagcgaga cagcagcgcg cactgcctaa
     6061 cgcgcatttg cttgcaactc cggtctcgcg cgagcaatca ctgacgtggg cgacccggct
     6121 gcgcgccgtt catgcaactc cagtctcatg cgggcaatct gatatgcaat tgggtgtcgt
     6181 tattgcaaat ctgggctcag attggctctt ggatcgcaga ttatctcgcc gtatttgcaa
     6241 acgcagtctc atcatgggca actatgacgc gtctgccggg tcccagcgag accgctgctg
     6301 caggacaggc aatctaggag cgcgcagacg tgcctttctc gcaaacccga ctatggcaag
     6361 gcgctcgcga accgcttgcc gtgccatatt tgcaaactca gtctcaattt gcggatttta
     6421 atatgcagat acagccacag attctcgcac tcccggatgc gcatctgcaa tctgcgtaaa
     6481 tgtgtaaaaa gggacatcgc agacccgtgc acgtccccaa ttacgcaaaa caacagggca
     6541 acagaacgca ggcgatcgcc gccggaagac gcggtgcccg ctacaactct gcgggaaaga
     6601 actctgcgtg aaagggaacg ctagctctgc gtaaaaaggg acatctccga cccgcagatg
     6661 tcccaaatta cgcaaaggaa gaaaaggaag aggggaagca gaggcaaaga attactgaaa
     6721 gtaatagtct gcgtaaaagg ggacagacag aacgcctatc tgtccccaat tacgcagatg
     6781 cgctagccgc ccatgcgcca ctccccgccc atgcgctacc cgcagacgcc cgctcgccgc
     6841 tccactcccg cagcgcaggc ggcagaacgg gtcgcgggtt acttcacggc accgcgcatc
     6901 acaccgccga cgacccactt ctgggcgaag atgtagacga cgagcacggg ggccatggcc
     6961 atcaggtagc tcgcgaacgc ctgcggatag ttcgtggcga actgcgagct gaacacatac
     7021 tgcgcgagcg ggatggtctg gttgctctga tcggtgagga tgataagcgg cagcaggaag
     7081 tcattccatg cccacagtgc ggtcatgatc gcaatcgtcg cgttgatggg ccccatgagc
     7141 gggaagatga tcttccagaa gatgcgccat gtgcccgcac cgtcgatgcg cgcggcctct
     7201 tcgagcgaca ccgggattga gcgaatgaat ccggtggcga tgaacaggtt cgtgccgagg
     7261 ccgagaatca cgtacaggac gatcaggccg gcctggttgt cgaggtgcca cgagcccatc
     7321 tgcttggcga gcggcagcat gaccaccggg aacggcacga acatggcggc gatgaagaag
     7381 tagtagagga agcggaagaa acgcttgtcc atgttgcgcg cgatcgcgta ggcgacgaag
     7441 gtgttcgtca cgagcgtgag cgagacggcg agcacggtga tgatcgccga gttgagcgcg
     7501 gcgcgcgggt agtccacttt ggccgaggcg gccgcgaaat tgccccactg ccagctcgtc
     7561 ggcagcgaga atgtgcccgc ctccgccggc gtcttcaatg cggtgaccac ggtgaaatac
     7621 agcggcacga gaatcgtgag gctgaacacg gcgacgaccg cggtgagcca ccagttgatg
     7681 cggcggtcct tgcggaactt ctccgctttg gccggcgcgg tattcatggt tgcagattgt
     7741 tgcgcagact gctgcgacat ggtgtttgcg gttgcggtgg tcatggtctc acaccttttc
     7801 cttgctgccg aagaacttga gctgaatgaa cgcgatgatc gcgaggacga tgaagaagag
     7861 cacggcgttc gccgtctggt atgcgtactc gccgccggtg agaccgccct tccagatgag
     7921 gtaggtgacg gtctcggtct tcgagttcgg gccgccgtcg gtgagcgcga cgacctggtc
     7981 gaaggtgccg agcgcgttct tcatggtgag tacgagattg attgtgaaga acggtccgat
     8041 gagcgggaac gtgatcttcc agaacttctg ccaggcgttc acgccgtcga tcgcggccgc
     8101 ctcgtagacc tcggagtcca cggtctgcaa gccggcgaga tagatgagca ccgaataggc
     8161 gacgccctgc cacacggcga ggaacacgat cggaatccac gcatagcgct cgctggtgag
     8221 cagcgactcg ctcagccagc caatgccgag cgccttgccg agctcgggca gcggctgcat
     8281 gaagatgtac ttgaacacgt agcctatgac gagcacggcc agcgtgtacg gaatgaagta
     8341 gattgcgcgg aagccgttct tgcaggcgat cttgccgttc agcgccaccg agaggaacaa
     8401 tgcgatcacg ttgatgagca cggtgatggc gatggcgatg aggaatgtga acagataggc
     8461 gtggccgacc cgttcgtcgc ggaacagggc gaagtagttc tggaacccga tccagttgca
     8521 gctgccgtac ccttgcgaat tcgtgaacga gtacatgatg ccgcgcacga agggcacata
     8581 caggaacacc gcgaagatca cggcggccgg aacggccatc cagtaatagg cgtggtccac
     8641 cttgcggcgc gagaacgcgg agaccctgcg tttgcggggc ggtttgcccg cgggtgtgcg
     8701 cgagtgatgc gtgtcgatgt cattcgcaag cacgtcctcc atggcgcgcg cctgctggtc
     8761 ggcattggcc aacgaagtca ttttgctttc cttcccttgt atcccggccg cagactactt
     8821 gcggaagtca cgagcctgga ccttgttcca ctcgttctgc atggagtcga tgaactggtt
     8881 cacgttgccg ctcatgatcg cggactgcag gtagccgcct atgttgatgg acgacggaat
     8941 gtagtggtcg cagaagtccg ccacacggtt gctctcgaag aacgggcgca ccggctcgag
     9001 cgccttgttg ccgaaatagg tctccttgag cggcgtgatc gcggactgcg cgtcggcgta
     9061 gttctcgagc tgcttcttgc tcatgaggaa ccgtatgaag cgcatcgact gttccttgtg
     9121 cctgctgttc gcgcccattg tgaggatcac gtcgtcgccg gcggtgagga tctgcttgct
     9181 cgcatcgttc gtggcgggca tctgggcgaa gcccaggtcg atgtctttgt tgaccatcgt
     9241 gatctgcgga atcgcatagg taccgagcgg aatgatcgcg gccgtgccct tggcgaagtt
     9301 ctgcgtgcct tgctggtagg tgacgccctt ctcgctgtct gcatacttga acagttcgat
     9361 ttccttctcg atcggttcgg tccagatctg cttgaacgtg gtgtcaccgc ttttcagcgc
     9421 ggcatattcg ctctcgggaa ccaatgtgcc ggcaagcgag gcgaggggcg cctgcgtggt
     9481 ccaggcatcg gcgagcgtgg cctgcaccgg gttgatgccc gcatcacgga atttcttgag
     9541 catggcaatg aattcatccc atgtctgcgg cggattgtcg gggtcgagac cgaccttgcg
     9601 gaagagatcc ttgttgtaga tgtagccgga ggcattgccc gcgaacggca ggccgtacag
     9661 tctcttcttc gccgggtccg aggtctgcac gaggttcttc gcgatgttca ccatgccctc
     9721 gttgagttcg ctcaccagcg ggtcatcggt gaaatcatgg aacaccccgg aggcggcgaa
     9781 ggtgccgaag ctgtagtcgc cgttgaaggt aatcacgtcg ggcacgcggt ccttcacgaa
     9841 acgcgtgcgc aggtcggtct gcgcattcgc cgagttgttg atgttgatgc gaatgtcggg
     9901 gttctctttc tcgaactcct gtgccgcctg cttgaaccag tccgcggcct cggccttgaa
     9961 ctggaagaaa tcgagcgtga cctgcccgct gccggcactg ttgccgcagc ccgccgcgcc
    10021 cacgccgacc gccaacgcgc acaccgccgc gccgatgccg cggagcatgc gtcgcatggc
    10081 cgaacgtctc atccgtgttg cgaacttcat tctgactccc ttgtccattt ccactttcca
    10141 tcgccgatgg ctcccttacc ccggctgacg gttgccagtg tatggaaccg cccttttcat
    10201 tcccaccacc ccgcgtgcct tgaaacagtg taagtaattg gcgtatattt atatactcat
    10261 ggaaactaat tcggattcgc ttgattttcc acgctggttc agtcgttcgg atgctacgca
    10321 taatgtggcg cgcggcatca tgcaatacgg cccgatcgcg cggacgccgc tcgcgcagat
    10381 cttcaatctg tcgcagggcg cgctctcgcg catcaccagc gatctcattt acgacggcgt
    10441 gatcgaggag atgccggccg gcagcacgca ggcgggcaga ttgccgcagg gattcgacct
    10501 acgcgaatca agtgaacgcc gcggccgccc gcagaccgcg ctgcgcattc gcgaggactc
    10561 gcatgccttc gtcggcgtca acattcacga cggcgccatc acggtgtccg aggtgaacac
    10621 gatgtgccgc cccatcggca gtgacatcac cgaaaccgtg tcgaacaccg ccccacaggc
    10681 cgtggtcgag cagatcaccc gcatggtgcg tgaactcgtc gccgcctccc ccgacgcccc
    10741 cgcgcccacc gcgcttggtc tttcgctcgg cggccacgtc gaggacgacc gttacgtcac
    10801 cttcgcgccg ttcctgtact gggattccag cgttgacctg ggcggcatgc tgcagcggga
    10861 caccggcatt cccaccaagg tgttcaacga cctcgactcg gtgctgctgc acgaatgctg
    10921 gttcggcgac gccattggcg ttcccagatt cgccgtcatc acgatgggcg ccggcgtggg
    10981 ctattcgatc tccgaccacg gcgacccaat agacaacccc gacaaaagct atggtctggc
    11041 cggacatgtg ctgatcgacc cggaggggcc gcgctgctcc tccgggcata tcggctgctc
    11101 gcaatgcctg acgtccgact cgatcgccga ggaatactcg ggcatcatgg ggcgtgtgac
    11161 caccttcgag gagttctcgc acgatctgcg ggcgaaccgg ccgcaggcgc gcagactcgc
    11221 cgaacgcacc tgctaccggc tcggcgtgct tgtggcgacc gtctcgaatc tggcgatgcc
    11281 ctcacgcgtg ctcgtcagcg gggaaagctc gttcattgcg aagaagaacc gcgagttcat
    11341 tcgcaagggc atcgatgcct accggcacag ccaggccgcg ccggtcgaat tctcgattcc
    11401 gcggttcagc tggcggctgt ggtcggattc cgccgccgcc cgcgccatcg ccacctacat
    11461 tagctagcga aggcgcggcc gcaatggcgt gctacacgcg cgtcacgctg aacagcaccg
    11521 cgttggcggg gtgaatgctc ggcggtcgca gaccgtagct tgcgagtgcc tcgccggtca
    11581 tctccacgcc gttcgcattc caccaaccga gttcgctctg cccgttgccg atctcgccga
    11641 agggctcacc actcgccatg ttcagtgcga gcgggcgcac acgataggtg gcctgcgcgt
    11701 cgagtccggg gagcgcgatg ggcgcggccg ggtaggtctg cgacgtggtg agctgggtga
    11761 agcggtagac ggcacgcgca ccatccgcgc tgatcacacc gtccacgcgc acggtcgggt
    11821 cggctgcatc gtcatgcacg gcgacgccat gttcgaagtc gacgcggtgc tccttgtagg
    11881 cgtgcaccca ttcgcccaac aggtcgaggt cgtgctgcgg ctccttgagc agattccatt
    11941 cgatgcccag atgcccgaag aacgccatcg ccatgcgcat ctcctgactc gtcgcgcggt
    12001 gcgtggagtg cgcggggctg gcgccgacat gctcgccaat catctccgga ggcacgagca
    12061 gcgacgtgta gcgctggatg tcggcgcgct ccaccggatc cacgcagtcg gaggcccaga
    12121 tgcggtctgc gagctcgaga atgcccatgt cgacgcggcc gccgcccgac gagcagcttt
    12181 caatctccag gccggggtgg gaggtcttca agtcgtggaa catgcggtag acggcgagcg
    12241 tctgcccatg gaccgcgcag ctgccggtgc gcggggagac cgcctcggtc acgtacttgt
    12301 tgtggtccca tttgatgtag tcgatgccga gctcgccgac gagcgagtcc atgcagccgt
    12361 acacatacgc atacgcctgc ggattcgtca ggtcgacgac ctgctggttg cgcccctgca
    12421 tcggcaggcg gtgcgcggtg ggcatgagca cccagtcgga gtgctcgcgg tacatcgcgg
    12481 aatccgggtt caccatctcc ggttcgaacc acaggccgaa ctccattccc ttggcatgca
    12541 cgtagtctgc aagcgccttg agcgagtgct cgccgtcggg ccacacgtcc tgggagatcc
    12601 gccagtcgcc caaacccgcc gtgtcaccac ggcggtcgcc gaaccagccg tcgtcgacca
    12661 cgaagcgctc gacgccgctc gcggcagcct tgtctgcgag cctgacaagc gtatcgtaat
    12721 catgctcgaa atacacggcc tcccaggtgt tcaggatcac cggacgcggc ttgtcggcaa
    12781 tgccatgctc ggcacgccaa cgcgcatggg tggcgcgcag gtcggcgtgg aagcgtgcgg
    12841 cgacttcgtt gagcccctcg ccgaaggaac cgtagagcca cggcgtggtg taggagtccg
    12901 cggcatcatg caacgtgatc tcaccgcccg caagcacttc cgcgccgccg atcacaccgg
    12961 tcgtgtatgg caggcgctcc gccgccatga gtgaattgcc gctccacgcc acatgcaccg
    13021 catacacgtc gccatgcgtg aagccgaagc cggggcgacc tgcattgagc agcagcgaag
    13081 cgtcgaagtc ggggcgcccc accatgctcg ccttctggaa ccgaccgatc gtcagcggct
    13141 ggcgctgcgg tgaacgttca cgcaaatgat gcccggtggt ggtgagcaac tcggtcatgt
    13201 cggccggcac cgggaaaccg agttccacct tgccgatctc cagactcccc gcgcccagat
    13261 tgcgcacgtc cgcgcgctga cgcaccaggc cgctgtcgcg catctcgcag gtccagatga
    13321 tctcgacccc ctgttcggca tcgctggcgg taacggcaac cccggcgtca cccaccgcga
    13381 tgtcggtgac gacgaaacgg cagaagagct ccacgccatc gcgacgcacc acgaaacgcg
    13441 gctcaccggt ccatgcctcg gcctgcgtgg gcagcacgct cggccatgtg gtctcgtcga
    13501 gcgcgccgga gacccgttgc gggcgcaggg cgtccactgc gctcaccagc gtgcgtggct
    13561 gggtgagggg gcgcccccaa tgcaccacac gcggcaactc gtcggccacg aacgcgagcg
    13621 cgaacgccga atccgcgtcg tggttctcca tggagaccac atgcaatgcc tcgccggcgt
    13681 gcgtggtcgc gttgaattcg gaaatccgtg tcat
//
