LOCUS       NC_017943              18924 bp    DNA     linear   CON 10-FEB-2020
DEFINITION  Haloferax mediterranei ATCC 33500 plasmid pHM300, complete sequence.
ACCESSION   NC_017943
VERSION     NC_017943.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN02603397
            Assembly: GCF_000306765.2
KEYWORDS    RefSeq.
SOURCE      Haloferax mediterranei ATCC 33500
  ORGANISM  Haloferax mediterranei ATCC 33500
            Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria;
            Haloferacales; Haloferacaceae; Haloferax.
REFERENCE   1  (bases 1 to 18924)
  AUTHORS   Han,J., Zhang,F., Hou,J., Liu,X., Li,M., Liu,H., Cai,L., Zhang,B.,
            Chen,Y., Zhou,J., Hu,S. and Xiang,H.
  TITLE     Complete genome sequence of the metabolically versatile halophilic
            archaeon Haloferax mediterranei, a
            poly(3-hydroxybutyrate-co-3-hydroxyvalerate) producer
  JOURNAL   J. Bacteriol. 194 (16), 4463-4464 (2012)
   PUBMED   22843593
REFERENCE   2  (bases 1 to 18924)
  AUTHORS   Cai,S., Cai,L., Liu,H., Liu,X., Han,J., Zhou,J. and Xiang,H.
  TITLE     Identification of the haloarchaeal phasin (PhaP) that functions in
            polyhydroxyalkanoate accumulation and granule formation in Haloferax
            mediterranei
  JOURNAL   Appl. Environ. Microbiol. 78 (6), 1946-1952 (2012)
   PUBMED   22247127
REFERENCE   3  (bases 1 to 18924)
  AUTHORS   Wang,L., Yang,H. and Xiang,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-MAY-2014) State Key Laboratory of Microbial Resources,
            Institute of Microbiology, Chinese Academy of Sciences, NO.1 Beichen
            West Road,Chaoyang District, Beijing 100101, China
  REMARK    Sequence update by submitter
REFERENCE   4  (bases 1 to 18924)
  AUTHORS   Han,J., Zhang,F., Liu,H., Lu,Q., Cai,S., Feng,B., Zhang,B., Cai,L.,
            Li,J., Li,M., Wu,Z., Liu,X., Liu,J., Zhou,J., Zheng,H., Hu,S. and
            Xiang,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (13-JAN-2010) State Key Laboratory of Microbial Resources,
            Institute of Microbiology,Chinese Academy of Sciences, NO. 1 Beichen
            West Road, Chaoyang District, Beijing, Beijing 100101, People's
            Republic of China
COMMENT     ##Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.6
            Coverage                          :: 100
            Sequencing Technology             :: 454
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/10/2020 21:08:38
            Annotation Pipeline               :: NCBI Prokaryotic Genome
            Annotation Method                 :: Best-placed reference protein
            Annotation Software revision      :: 4.11
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
            Genes (total)                     :: 3,870
            CDSs (total)                      :: 3,805
            Genes (coding)                    :: 3,737
            CDSs (with protein)               :: 3,737
            Genes (RNA)                       :: 65
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 2
            Pseudo Genes (total)              :: 68
            CDSs (without protein)            :: 68
            Pseudo Genes (ambiguous residues) :: 0 of 68
            Pseudo Genes (frameshifted)       :: 30 of 68
            Pseudo Genes (incomplete)         :: 44 of 68
            Pseudo Genes (internal stop)      :: 22 of 68
            Pseudo Genes (multiple problems)  :: 23 of 68
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence was derived from
            CP001870.
            Source DNA is available from Prof. Hua Xiang's laboratory, at the
            Institute of Microbiology, Chinese Academy of Sciences, Beijing
            100101. The archaeal strain is available from the China General
            Microbiological Culture Collection Center, Beijing 100101.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotation Pipeline (PGAP)
            set; GeneMarkS-2+
            repeat_region
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..18924
                     /organism="Haloferax mediterranei ATCC 33500"
                     /mol_type="genomic DNA"
                     /strain="CGMCC 1.2087"
                     /culture_collection="ATCC:33500"
                     /type_material="type strain of Haloferax mediterranei"
                     /db_xref="taxon:523841"
                     /plasmid="pHM300"
     gene            complement(1..1131)
                     /gene="ugpC"
                     /locus_tag="HFX_RS15565"
                     /old_locus_tag="HFX_5025"
                     /db_xref="GeneID:13025761"
     CDS             complement(1..1131)
                     /gene="ugpC"
                     /locus_tag="HFX_RS15565"
                     /old_locus_tag="HFX_5025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008319396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q8TZQ3|3.A.1.1.16"
                     /protein_id="WP_004056420.1"
                     /db_xref="GeneID:13025761"
                     /translation="MSQLELRNLRKEFTGGGESVVAVDDVDLTLNDGEFLVLVGPSGCG
                     KSTTLRMIAGLESVTSGDVIVDGESMTDLEPRERDIAMVFQNYALYPHMTTRENIGFGL
                     KMTTDLDSEERNRQVEDVAESLGIEELLDDYPKELSGGQQQRVALGRAIIRDPEVFLMD
                     EPLSNLDAKLRTQMRTELKALQDDLNVTTVYVTHDQTEAMTMGDRIAILNHGELQQVGT
                     PLECYHQPANKFVAGFIGAPSMNFMDVASKNERLIHKMFDYEISEATAQAIEGYDRVTL
                     GIRPEDIRIVDGSDVQNPIPAEVHLVEPLGDVSHVALNIGNKRFTAAVPGGQKFDRGEE
                     VTLHFPEDSLHLFDATSGQTLKNSSRSADEEPVIHA"
     gene            1301..2527
                     /locus_tag="HFX_RS15570"
                     /old_locus_tag="HFX_5026"
                     /db_xref="GeneID:13025762"
     CDS             1301..2527
                     /locus_tag="HFX_RS15570"
                     /old_locus_tag="HFX_5026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008326719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="WP_014732644.1"
                     /db_xref="GeneID:13025762"
                     /translation="MTEQRYRSHTDSIYGELDVPTVVNAAGTKTRIGGSLIRAEALEAM
                     NDAASTFVELGDLQAAASDRIAEITGAEAGYVTSGAAAGLCLSAAAAIAGHDIAAMDRL
                     PDTEGLPSEILMPRTHRTGYDHALRAAGATIVDIGTNDLHLGTGSTNVEPWEIEANITD
                     ETAAIAYMEKSYTEPPLDVVADIAHDHDIPVIVDAAAELPPRSNFSRFIEQGADLVVFS
                     GGKGIRGPQTTGIVAGKQEYIESIALQHLDMHVAEAAWSPPKRLIDLDNFAGVPRQGIG
                     RSMKVGKEELVGLIYALEAFMEEEQAETQREWQNRADNIACAIEDAGLETHVTGGSDVS
                     VAPEVVINVDESSETTAIELVRRLRAENPRVYLGGDRIDEGEVVANPMCITDDEADYVA
                     DRIVANVEN"
     gene            2577..3284
                     /locus_tag="HFX_RS15575"
                     /old_locus_tag="HFX_5027"
                     /db_xref="GeneID:13025763"
     CDS             2577..3284
                     /locus_tag="HFX_RS15575"
                     /old_locus_tag="HFX_5027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004056418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STP|PIG-L"
                     /protein_id="WP_004056418.1"
                     /db_xref="GeneID:13025763"
                     /translation="MKLLAIVAHPDDAAIFCGGTLAKHAERGDHVTVAHMTRGEYGGLG
                     SDTEEDVATVRTEESRAAGDVLGVDEVEFLGFKDGRVEYSLENRLALVDTLRKYDPDVV
                     LTHFKDDMHPDHQATARLVTDAYYMASLPLVETDFEPCDPDNIYFFGKPTSSFEAETFV
                     DISGYLDTKIGALEQHVSQIDFLIDHGGIDAEFDNLVDSLRAEGMTLGKRVGCEAAEGF
                     APLHEQARDFLMD"
     gene            3331..3705
                     /locus_tag="HFX_RS15580"
                     /old_locus_tag="HFX_5028"
                     /db_xref="GeneID:13025764"
     CDS             3331..3705
                     /locus_tag="HFX_RS15580"
                     /old_locus_tag="HFX_5028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007541647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="reactive intermediate/imine deaminase"
                     /protein_id="WP_004056417.1"
                     /db_xref="GeneID:13025764"
                     /translation="MRELTTDDAPASIGPFSQGIETDGTIYVSGQGPIDPETGDVVSQD
                     VREQTRQTLANVEAVLRAGGASLDDVVKATVFVNDMRYYDEVNEVYGELLSSPYPARSA
                     VEVVKLPVDIKVEIEVVAEA"
     gene            complement(3803..5395)
                     /gene="nagZ"
                     /locus_tag="HFX_RS15585"
                     /old_locus_tag="HFX_5029"
                     /db_xref="GeneID:13025765"
     CDS             complement(3803..5395)
                     /gene="nagZ"
                     /locus_tag="HFX_RS15585"
                     /old_locus_tag="HFX_5029"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004056416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH3"
                     /protein_id="WP_004056416.1"
                     /db_xref="GeneID:13025765"
                     /translation="MADNVLTAERPVHAVPLEEKVGQLFVAGFDGVEPTDDIEQLVSSH
                     HLGGIIYFSRNIESPSQVASLSERLQTIAREAGEPPLLIATDQEGGVVSRFDWGAQLPS
                     QMALGATQDPTRLRSAGETVGEELASLGISMNFAPVLDVNNNPENPVIGVRSFGDDPEA
                     VGELGSALASGFQSAGVIACGKHFPGHGDTETDSHRSLPVIPHDKDRLEAVEFVPFRRA
                     IDDGIDALMTTHIAFPAITGDDTLPATLSKEVLTGLLREEFEFDGLLVSDCLEMNAIAE
                     TVGTAEGAVQAIAAGCDVVLVSHSPERQREAIERVIDAVESGEIPEARVDSAFERVREY
                     KHRQFTEEREKPQTWTETVEQSREVARQLAREGATVVRDRDDTLPFDTSAPIHLVGFTG
                     DAQSDAEDDRYDPNDFRTSLARNETKVYHHEVTDTHGYEHPFDGGEQVVVATYHARSNP
                     GQARVVREIADAATRLAVVSVRDPYDLAAVPDASTYVTGYGYSPAMLDALADVVVGKAG
                     GDGTLPVTIPGVE"
     gene            complement(5492..6403)
                     /locus_tag="HFX_RS15590"
                     /old_locus_tag="HFX_5030"
                     /db_xref="GeneID:13025766"
     CDS             complement(5492..6403)
                     /locus_tag="HFX_RS15590"
                     /old_locus_tag="HFX_5030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007541643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|G4FGN6|3.A.1.1.41"
                     /protein_id="WP_004056415.1"
                     /db_xref="GeneID:13025766"
                     /translation="MLSALQTEDEDGRIPESWRLTTDGRELLFDAFARFALGLVLLFAL
                     FPIWMMVMNSFKSRSQVMTENPTLIPTEFHVSNYFEMWQRFPLFEYFLNSLIIASVTTV
                     VTILIASLAAYAFSRYEFPGKAKLELSILGTQMIPGVLILLPMYLLFINIQMQVGLPMK
                     DTYHGLIFLYSTFTIPFAIWMLRGYFDTIPKALGEAARIDGCTRLEALFRVVMPLAAPG
                     IAATSMFVFLLAFNEVLFASVLGSDSVTPFAIGIQEFQTQTQTYWGQMMAASTVATIPL
                     LFLFVLFQKPIVSGLTSGSVKH"
     gene            complement(6405..7382)
                     /locus_tag="HFX_RS15595"
                     /old_locus_tag="HFX_5031"
                     /db_xref="GeneID:13025767"
     CDS             complement(6405..7382)
                     /locus_tag="HFX_RS15595"
                     /old_locus_tag="HFX_5031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008326734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q72H67|3.A.1.1.25"
                     /protein_id="WP_014732645.1"
                     /db_xref="GeneID:13025767"
                     /translation="MLERARSGITRAVPNWVQARLPRLSDDTRFAYKLLLPAFVMMGLI
                     HFLPIIWGFYISFVQLDAAYVSNWWNAPIVGFENYAKVFNPNTIVGAEFWTSLRQTLIF
                     TVGSVMGIYTLGLATALLLNRDFRGKLAARTLVLVPWIAPAVVTVLTWQMMFRTDTGMI
                     NHILRSVGLIDGSFFWLIGPRSILAITAVWTWQNFPWAAIMLYAGLQSIPEHLYEAAET
                     DGAGRWGKFRYITMPQLKPVSVVIVLLMVVWTLINFTVPYVLLGSSPSDSGKVLMLFIY
                     NYAFTNWSFGLGAAMSAILFIVAMILAYIYYSRVIDGEFEGGAI"
     gene            complement(7534..8850)
                     /locus_tag="HFX_RS15600"
                     /old_locus_tag="HFX_5032"
                     /db_xref="GeneID:13025768"
     CDS             complement(7534..8850)
                     /locus_tag="HFX_RS15600"
                     /old_locus_tag="HFX_5032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008326735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STP|SBP_bac_1"
                     /protein_id="WP_004056413.1"
                     /db_xref="GeneID:13025768"
                     /translation="MEDASTRNLSRRQLLAGAGAATATGLTGCLGQFGNKTKQSSNDVT
                     LQARHFATPGVEKFYEKHAAKFEEETGIAVEVETMGWGNAKQKQLNSITSRDGPDIEEI
                     ASTWMPQQVQSDAWMDLGELGISLDGVYDQPTNVANYDGITTGFPWFWGPRGHLVHQGM
                     LDEAGISDQPTSWDQLVEQSKQFKETFPEKHLFGLPGANNWAVTQFYAMFVWQAGGSLL
                     SDDKSEAVFNSESAVKALNFYKDLATEYEVAPKASAEWDGPARDSAFINKRIAGTWSAL
                     NTVDKVVSEGDATRDSMAVYKPPAGPNGQSATFYGVNLVGIHPWTDYPDEAAKWLKYLM
                     RPAVNADVASMTGFLPTIKSGFDQEQFSGPLYQKFSDEVLPGAKTFPQVIGWGEVEGTI
                     KNAVTDILTKGVSGDWSEGDTKAALDKAVQQANNVLSEN"
     gene            9002..10153
                     /gene="dgoD"
                     /locus_tag="HFX_RS15605"
                     /old_locus_tag="HFX_5033"
                     /db_xref="GeneID:13025769"
     CDS             9002..10153
                     /gene="dgoD"
                     /locus_tag="HFX_RS15605"
                     /old_locus_tag="HFX_5033"
                     /EC_number="4.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007541638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactonate dehydratase"
                     /protein_id="WP_004056412.1"
                     /db_xref="GeneID:13025769"
                     /translation="MKITGYDLYELPPRWLFLKIETDEGLVGWGEPIVEGRAKTVKTAV
                     SEMLDGYLVGKDPLRIEDHWQALYRSGFYRGGPILMSAIAGINQALWDIKGKHYDAPVY
                     ELLGGKSRDKIRVYQWVGGDRPDDVIEEAHRLVDTGYTALKMDATNQTRHIETAASIEQ
                     VVDRIRKVREAVDNTVDIGVDFRGRVSKSMAKMLTNRLSDLDLMFVEEPVLPENVEYLP
                     EIATQSQIPIATGERLYSRWDFKQLFGGGAIDLIQPVVSHAGGISEMVKLATMAEAYDV
                     GIAPNCPLGPIALAASLQVDTHIPNLVVQDNGFDIHSPDRGPAYDYLEDTSVFSFKDGY
                     LDTLDEPGLGISIDEETVEARSGAHVEWHNPTWRNEDGSITDW"
     gene            10220..10963
                     /locus_tag="HFX_RS15610"
                     /old_locus_tag="HFX_5034"
                     /db_xref="GeneID:13025770"
     CDS             10220..10963
                     /locus_tag="HFX_RS15610"
                     /old_locus_tag="HFX_5034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004056411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DBD-Pfam|HTH_5,DBD-SUPERFAMILY|0040266"
                     /protein_id="WP_004056411.1"
                     /db_xref="GeneID:13025770"
                     /translation="MTDRSQVPTLSAPKKTFALIEEMADRDGPVRVSDLAEELGFTRST
                     TYKHLATLRELGYVRKVGVEYALSYRFVLFGTRIRGRSPLYRASNELIDQLAETTNETT
                     GLLVKQGSYGVNLYQSTSDRSETVEIDQHLHCTAPGKAILAHLTDEQVDHVVDAVGLPA
                     RTDNTITDPGVLADELTNVRERGIAIERGEQHPDQNGVAVAFEHDNEVAAVYVVGHADR
                     LSSKRLEENIPGMVLGTVRRTKELL"
     gene            complement(10982..12052)
                     /locus_tag="HFX_RS15615"
                     /old_locus_tag="HFX_5035"
                     /db_xref="GeneID:13025771"
     CDS             complement(10982..12052)
                     /locus_tag="HFX_RS15615"
                     /old_locus_tag="HFX_5035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008326743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose 1-dehydrogenase"
                     /protein_id="WP_004056410.1"
                     /db_xref="GeneID:13025771"
                     /translation="MRAIAVHRGEESPRVIDVPTPEPADGEVLVKTLRVGVDGTDHEVI
                     KGTHGGFPPGDDYQILGHEAIGVVVDPTTTGFEEGDIVIPTVRRPPDGTNEYFERGEPD
                     MAPDGKYLERGIVDAHGYMSEYFTSAAEFLVEIPESLAPHGFLVEPMSNAEKAIQHAFA
                     TRAAFSWEPESALVLGNGPLGLLTLARLARDVDDLYCLGRRDRPDPSIDIIEKLGATYV
                     DSRETPVPEIPTEYGHVDIAIEATGYAKHAFEVLDALAPNGVGALLGVPSDWEFEIDGG
                     RLHREMVLQNKALVGSVNSHIPHFEMAIDTVSSLPDWFIDDVVTEVVPAADPSAAFERN
                     KEQIKTAVEFVPPSER"
     gene            12032..12235
                     /locus_tag="HFX_RS19805"
                     /db_xref="GeneID:43882276"
     CDS             12032..12235
                     /locus_tag="HFX_RS19805"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_137685702.1"
                     /db_xref="GeneID:43882276"
                     /translation="MDGYRTHYSILRPLRSSGASYLALFDLPIGLCRIRCREPVSPTQG
                     ALGKAIITTHVTGLGQIPSGNQ"
     gene            complement(12379..13797)
                     /locus_tag="HFX_RS15620"
                     /old_locus_tag="HFX_5036"
                     /db_xref="GeneID:13025772"
     CDS             complement(12379..13797)
                     /locus_tag="HFX_RS15620"
                     /old_locus_tag="HFX_5036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007541632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PKD domain-containing protein"
                     /protein_id="WP_004056409.1"
                     /db_xref="GeneID:13025772"
                     /translation="MTQNRRTYLRNVSALVTSVAGVGAASTAVSAESPPKWDETTLYEK
                     GDRVTYEGYIWEADIASRNAEPSTDSAYWTKVGPDDGGDDESLTAAFTIDDATVTPGTS
                     VSFDASESTGTVDTYDWSFTDGASASGKTVSHSFESTGSYGVKLTVTGSDGATDTTDKT
                     VTVESSDGGGTPTGSLPSNVFAPYDHVSTNSETAPIDHAKKAGTNYFHLAFVLAGPDGK
                     PAWDGDSNQLVGESSVGGYIDDIHAAGGEVIIAFGGAAGPYLADGTDDPAVLADHFETV
                     VDAYGATHLDIDEEAFAMSTVKRRNEALAMLQERRPEVSVSFTLPTSTKGLTAQGKDVL
                     QDAIDKGVTIDTVNIMTMNYGWVEPSGDIVTQSASNLHDDLGTLFPDKSAGERWSMVGI
                     TPMIGVNNVGGKFTQADAKQVLTFAQDNDIGLLSFWSIDRDNGTGSGEVSPVKSGIDQE
                     PYEFSSIFAPFTSE"
     gene            complement(13852..15294)
                     /locus_tag="HFX_RS15625"
                     /old_locus_tag="HFX_5037"
                     /db_xref="GeneID:13025773"
     CDS             complement(13852..15294)
                     /locus_tag="HFX_RS15625"
                     /old_locus_tag="HFX_5037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004056408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBM5"
                     /protein_id="WP_004056408.1"
                     /db_xref="GeneID:13025773"
                     /translation="MKQNRRSILRSIAGLTGVAGLSTAGIQSVKAAGDYPQWDPDTVYT
                     DGDRVVHDAHIWEAKWWTKGDEPSADANMWKGIEPADNAGDPPTAAFDVSATFVQPGTE
                     VTCDASASTGDLSSYEWDFGDGTTGTGLTTAHAYDATGDYTISLTVTDADGNTADATRN
                     LTVDADGVPSANPIPDSVFAPYVDMMLEDQLSLAANVEAAGTKYFTLAFVLADGNGDPA
                     WAGSQKVGEPSNWLDVGTQLTELRDQHGGEVIVSFGGLNGTYLAEATTSASELKDAYAT
                     VVDTYDLTYIDFDEESLISRDEESIRRRNEALVMLQDEYPDLHVSYTLPVMPSGLPGHS
                     SNDVLFVLEDAVSKGVELDAVNLMVMDYGADIEPNAENAISAAESVHKQLGDLYPNKSA
                     SERWSMLGLTPMIGVNDIGGTFYQEDARQVLDFAQNHDLRLLSFWELVRDNGKGDKLYE
                     STLIEQEPFEFSSLFNPFTTNQ"
     gene            complement(15291..17003)
                     /locus_tag="HFX_RS15630"
                     /old_locus_tag="HFX_5038"
                     /db_xref="GeneID:13025774"
     CDS             complement(15291..17003)
                     /locus_tag="HFX_RS15630"
                     /old_locus_tag="HFX_5038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006054549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBM5|GH18"
                     /protein_id="WP_014732646.1"
                     /db_xref="GeneID:13025774"
                     /translation="MRQSRRSYLRNTSALLALLSGASATASAAETPPTWEPDVAYTGGD
                     RVTHNGYIWEAKWWTKGDEPTTDANMWKQIGEAGGGGGIKAAFTASDTYVEPGVEISFD
                     ASGSSGSPTSYEWDFGDGATGTGETVTHTYESEKEYTVTLTVGNEDGTDTTSKQVTVSQ
                     NAPSDEFSVVGYYPSWKGNEDYQYYPEDIPFDKVTDVLYAFLNVKSDGSVVIPDSEVDH
                     KGLLQSFADLKQGPAADTTLKLSIGGWALSPGFEDAAANEANRTRFAETAVSLMRKYDF
                     DGIDIDWEHPGPNRGACECGSSEGPANHVKLLKAVRNKLDTVEEEDGRTYYLSVANGGS
                     DWNASLVKHREVERVVDEIYMMSYDFTGVWHETAGLNAPIYGTPDDYPPSGDAQQYTLE
                     TTLEIWKEQGYWVDWMQWEDYGEPVEDPASLVLGLPFYGRGCKVENGIWDTFSLSDWQQ
                     GDPQYQNEVIPPGTWNHLLGSDQANTGAFDYGDLEENYEGADGWQKNVNEQGQVPWLWN
                     EEKGIFISYDDPASIEEKVKLAKSEGLGGVMFWELSQDYNGSLLDAIDGQVNQ"
     gene            complement(17302..18924)
                     /locus_tag="HFX_RS15635"
                     /old_locus_tag="HFX_5039"
                     /db_xref="GeneID:13025775"
     CDS             complement(17302..18924)
                     /locus_tag="HFX_RS15635"
                     /old_locus_tag="HFX_5039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006054550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBM5|GH18"
                     /protein_id="WP_004056406.1"
                     /db_xref="GeneID:13025775"
                     /translation="MKQSRRDYLRNTSALLALLGGAGTAVAAETPPKWDPEATYTGGDR
                     VTYNGYIWEAKWWTRGTEPSTDASVWKQIEPVDDGGDGPKASFTASDLVINPGQTVEFD
                     ASGSGDTATEYDWDFGDGATGSGKVVSHTYDSVGEYTVKLTVTDDSGATGSTTKVITAS
                     DGGMPTDKRVVGYYMQWAQWDREYTPGDIPLDKVTHVNYAFLTVKQDGAVDYINENAAY
                     RVLKPESWHDHKGFNEIVDDPTTKFLFSIGGWNDSKYFSNAAETEASRQRFAKTAVEIM
                     REHNFDGLDIDWEYPGGGGKSGNIVRDGDKKRYSDLLDAVRAELDAAEQEDGQEYLLTT
                     ALSADPKKNNGLDHQRNTGLLDFVNVMTYDFHGAFDDYTNHQSPLYFKENDPSPRAEDF
                     NVDAAMSYWANTAFDSSQLSMGLPFYGRSFGNVASSDNGGLYQSFEGSPDGTWGQDNGI
                     MEFWDINKNLEPSSEYDYHWDDTAKVPWIYSNNSDVLVSYDNPKSIGIKTDYAVNNDIG
                     GMMFWAFSGDKNEVLLDTLLEHL"
ORIGIN
        1 tcaggcgtga atgacgggtt cttcgtcggc cgaccgcgaa ctatttttca gtgtctgtcc
       61 ggaggtggca tcgaacagat ggagactatc ttcggggaag tgtagtgtta cttcctcacc
      121 gcggtcgaac ttctgaccac ctggaacggc ggccgtaaac cgcttgttgc cgatgttcag
      181 tgcgacgtgt gacacgtccc ccagtggttc tacgaggtgc acttcggcgg gaatcgggtt
      241 ttggacatct gaaccatcca cgattcggat gtcttccggc cggattccta acgtcacacg
      301 gtcgtacccc tcaatcgctt gggcggttgc ttcggagatc tcgtagtcga acatcttgtg
      361 gatgagccgc tcgtttttgg acgcgacatc catgaagttc atcgagggag caccgatgaa
      421 accagcaacg aacttattgg ccggttggtg gtagcactca agcggtgtgc cgacctgctg
      481 aagttctccg tggttcagaa ttgcgatgcg gtcgcccatc gtcatcgcct cggtctggtc
      541 gtgagtgacg taaacggtcg tgacgttcag gtcgtcttgc agcgctttga gttctgtgcg
      601 catttgcgtc cgaagcttgg catcgaggtt cgaaagcggc tcgtccatca ggaacacttc
      661 gggatcgcga atgattgcac ggccgagcgc gacgcgttgt tgttgcccgc cggacagctc
      721 tttcggataa tcgtcgagta gctcttcgat acccagcgac tcggcgacat cctcgacttg
      781 ccgattccgt tcttcggagt cgaggtcggt cgtcatcttc agtccgaacc cgatgttctc
      841 tcgggtcgtc atgtgcgggt acagggcgta attttggaac accatggcga tatcgcgctc
      901 gcgtggctcc aaatccgtca tcgactcacc gtcgacgatg acatccccgc ttgtgaccga
      961 ttccaatcct gctatcattc gaagtgtggt cgacttaccg catcccgagg gaccgacaag
     1021 aaccaaaaac tcaccatcgt taagtgtcaa atcgacatcg tcgaccgcaa cgacgctctc
     1081 gccccctccg gtgaattcct tccggaggtt acgcagctct aactgtgaca tgctttcttc
     1141 ccaacgttta cagtcaaact atataatgct ttgtcatcac tacccacgcg agacctccga
     1201 aaccccactt ttgagtcgaa gcgaacgttt atatgcaaag ctggtgacac aggaaagtat
     1261 ctggagtcac taacgactcg ttcgtttcca gtgagccaca atgacagagc aacgttaccg
     1321 gagtcatacc gactccatat acggagagtt ggacgtcccg acagtggtca acgcggccgg
     1381 gacgaagaca cgaatcggtg ggagcctcat tagagcagag gcactcgaag cgatgaatga
     1441 cgccgcctcg actttcgttg agcttgggga cctccaggcg gccgcttcgg accgcatcgc
     1501 cgaaatcacc ggcgcggaag ccggctacgt taccagtggg gcggctgctg ggctatgtct
     1561 ctctgccgca gcggctatcg caggccacga tatcgcagcg atggaccgtc tccctgacac
     1621 tgagggactg ccaagcgaga tactgatgcc ccggacgcat cgaaccggct acgaccacgc
     1681 cctccgcgct gcgggtgcaa ctatcgtcga catcgggaca aacgaccttc accttggaac
     1741 cggttcgacg aacgtggaac cgtgggaaat cgaggcgaac atcaccgacg agacggccgc
     1801 catcgcctat atggaaaagt cgtacaccga gccaccgctc gatgtagtcg ccgacatcgc
     1861 tcacgaccac gacatccccg tcatcgtcga tgcggccgcc gaattaccgc cacgctcgaa
     1921 cttctcccgt ttcatcgagc agggtgccga cctcgtcgtg ttcagtggtg ggaaaggaat
     1981 tcgcggccca caaacgaccg gaatcgtcgc tggcaaacag gagtatatcg agtccatcgc
     2041 tctccaacac ctcgacatgc acgtcgccga agcggcttgg tcgccaccga agcgactcat
     2101 cgacctcgat aacttcgctg gcgttccccg acagggaatc ggtcgctcga tgaaggtcgg
     2161 caaggaggaa ctggtcggtc tcatctacgc cctcgaggcg ttcatggagg aagagcaagc
     2221 agagacacag cgcgaatggc agaaccgagc cgacaacatc gcttgcgcca tcgaagatgc
     2281 cggattggag acgcacgtca ccggcggcag cgacgtcagc gtcgccccag aagtcgtcat
     2341 caacgtcgac gagtcgtccg aaaccaccgc tatcgaactc gtccgccgac ttcgcgccga
     2401 gaaccctcgc gtgtacctcg gtggcgacag aatcgacgag ggcgaagtcg ttgcgaaccc
     2461 gatgtgtatc accgacgacg aggccgacta cgtcgccgac cgcatcgtcg caaacgtcga
     2521 gaactgacaa ccgaaagtaa acttatttta gtcagttagt caaactgaca accgcgatga
     2581 aattgttagc aatagtcgca catccagacg acgctgcaat cttctgtggc ggaacgctcg
     2641 caaagcacgc cgaacgtggt gaccacgtca cggtcgcgca catgactcgc ggggagtacg
     2701 gcggtctcgg aagcgacact gaagaagacg ttgcgacggt cagaactgag gaatcccgcg
     2761 ccgcgggcga cgttctcggc gttgacgaag tcgagttcct cggcttcaaa gacggccgtg
     2821 tcgagtactc gctcgaaaac cgcctcgccc tcgtagacac cctccggaag tacgaccccg
     2881 acgtcgtcct cacgcacttc aaggacgaca tgcacccgga ccatcaggcg accgcccgcc
     2941 tcgtaaccga tgcgtactat atggcgtcac tcccgctcgt cgagaccgat ttcgaaccgt
     3001 gcgaccccga caacatctac ttcttcggga agcccacgtc gtcgttcgaa gccgagacgt
     3061 tcgtcgacat ctccggctac ctcgacacga aaatcggggc gctcgaacag cacgtctcgc
     3121 aaattgactt cctcatcgac cacggcggta tcgacgcgga gttcgacaac ctcgtcgata
     3181 gcctccgtgc tgaagggatg accctcggga aacgcgtcgg ctgtgaggcc gccgaaggtt
     3241 tcgcaccgct tcacgaacag gcccgagact tcctgatgga ctgagtatcg acccgacaat
     3301 cactttcaac tactcaaact acgctctaca atgcgcgaac tcaccaccga cgacgcaccc
     3361 gcaagtatcg gcccgttttc tcaaggcatc gaaaccgacg gcaccatcta cgtctccgga
     3421 cagggaccaa tcgaccccga aaccggcgac gttgtcagcc aagatgtacg cgaacagacg
     3481 agacagactc tcgcaaacgt cgaggcagtc ctccgtgctg gcggtgcctc cctcgacgat
     3541 gtcgtgaaag cgaccgtctt cgtcaacgac atgcggtact acgatgaggt aaacgaggtg
     3601 tacggcgaac tgctgtcatc tccatatcct gcccgcagcg cggtcgaagt cgtaaagctc
     3661 ccggtcgaca tcaaagtcga aatcgaagtc gtcgccgaag cgtaaccgac ccacccttat
     3721 tcgtcagttt tctccgcgga actcgtcatt cgacgttaga cccgtcattc tacactgagg
     3781 cccggatacc cctcttgaaa catcattcca cacccggaat cgtcaccggt agcgtcccgt
     3841 ctccgcctgc tttcccgaca accacgtccg cgagtgcatc cagcattgcc ggtgagtagc
     3901 cgtagcccgt aacgtacgtc gaagcgtctg gtactgcggc gaggtcgtag gggtcacgga
     3961 ccgagacgac tgcgagtctg gtcgctgcat ccgctatctc gcggacgacc cgtgcctgtc
     4021 cgggattcga ccgtgcgtgg tacgttgcga cgacgacttg ttcgcccccg tcgaatggat
     4081 gttcgtatcc gtgggtgtct gtgacctcgt ggtgatacac cttcgtctcg tttcgagcaa
     4141 gcgacgtgcg gaagtcgttc gggtcgtatc ggtcgtcttc cgcatccgac tgggcgtcac
     4201 cggtaaagcc gacgaggtgg atgggtgctg acgtgtcgaa cgggagtgtg tcgtcgcggt
     4261 cgcggacgac ggtcgctccc tctcgtgcga gttgtcgtgc gacctcgcgc gattgctcga
     4321 ctgtctccgt ccacgtttgc ggcttctcac gctcttcggt aaactgtcgg tgcttgtatt
     4381 ctctcacccg ctcgaacgcg ctgtcgacgc gcgcctcggg aatctcaccg gactcgacgg
     4441 cgtcgatgac ccgttcgata gcctctcgct ggcgctcggg cgagtgcgat acgagtacca
     4501 cgtcacaacc tgctgcaatc gcttgcaccg ctccttcggc cgttccgact gtctcagcga
     4561 tagcgttcat ctccagacag tcggagacga gcagtccgtc gaattcgaac tcctcgcgaa
     4621 ggaggccggt gaggacttcc ttcgaaagtg tggccgggag cgtgtcgtct cccgtaatcg
     4681 ccgggaaagc gatgtgagtc gtcatgagcg cgtcgatacc gtcgtcgatg gcgcggcgga
     4741 acgggacgaa ctcgacggcc tccagtcggt ctttgtcgtg tggaatgact ggcagcgacc
     4801 gatgcgaatc ggtctcggta tcgccgtgtc cggggaagtg cttcccgcag gcgatgactc
     4861 cagcggactg gaaccccgac gcgagcgccg accctaactc gccgacggct tccgggtcgt
     4921 ccccgaacga ccgtacgccg ataaccgggt tttcggggtt gttgttaacg tccagaaccg
     4981 gcgcgaagtt catcgaaatg ccgagcgagg cgagttcttc gccgactgtt tcgcctgctg
     5041 accggagtct cgttgggtcc tgagtcgccc cgagtgccat ctgactgggc agttgtgcac
     5101 cccagtcgaa ccgggagacg acgccgcctt cctggtctgt cgcaatgagg agtggtggct
     5161 cgcccgcttc gcgcgcgatg gtctggagtc gttccgagag cgacgcgacc tgcgacggtg
     5221 actcgatgtt ccgactgaag tagatgatgc caccgagatg gtgcgacgac actaactgtt
     5281 cgatgtcgtc ggtcggttcg accccgtcga aaccggccac aaacaactgt ccgacctttt
     5341 cttcgagcgg caccgcatgg acggggcgct ccgctgtcaa cacgttgtct gccatttcga
     5401 ccggacagtc gtgggggatg gtcttagtgc tactgtctga cgcacggctt agtgctacag
     5461 cccgagcaaa aaaatcgcct tgggggtgct gttagtgctt tacgcttccc gaggtgagtc
     5521 ccgagacgat tggcttctgg aacaggacga acaggaacaa cagcggaatc gtcgcgaccg
     5581 tcgacgccgc catcatctgt ccccagtagg tctgggtctg cgtctggaac tcctgaatgc
     5641 caatcgcgaa cggtgtgacg ctgtcagagc cgaggacgga cgcgaaaagc acctcgttga
     5701 acgcgaggag gaacacgaac atcgacgtcg cggcgatgcc gggtgctgca agcggcatca
     5761 cgacacggaa gagtgcttcg agtcgcgtac agccgtcgat tcgtgcagcc tcgcccagcg
     5821 ccttcggaat cgtatcgaag tatccgcgga gcatccagat tgcaaagggg atggtgaacg
     5881 tcgaatagag gaagatgagt ccgtgatacg tgtctttcat cgggaggccg acctgcatct
     5941 ggatgttgat gaaaagcagg tacatcggca gcaggatgag cacgccggga atcatctgcg
     6001 tcccgagaat cgacagttcg agcttcgcct tcccggggaa ctcgtaccgc gagaacgcgt
     6061 aggcagccag actggcgatg aggatggtga cgaccgtcgt cacgctggcg ataatgaggc
     6121 tgttcaggaa gtactcgaaa agcgggaagc gctgccacat ctcgaagtag ttcgaaacgt
     6181 ggaactccgt ggggatgagc gtcggattct ccgtcatcac ctgacttcgg gatttgaagc
     6241 tgttcatcac catcatccag atgggaaaca gcgcgaacag aagtaccaac ccgagcgcga
     6301 accgcgcgaa ggcatcgaag aggagttcac gcccgtcggt cgtcaaacgc cacgactccg
     6361 ggatgcggcc gtcttcgtct tcagtttgga gtgcgctcaa catctcagat agcacctccc
     6421 tcgaattcgc cgtcgatgac acgactgtag tagatgtacg cgagtatcat tgcgacgatg
     6481 aacagaatcg cactcatcgc agcgccgaga ccgaacgacc agttggtgaa cgcgtagttg
     6541 tagatgaaca acatgagcac ctttccggag tcgctcggac tcgacccgag aagcacgtac
     6601 gggacggtga agttgatgag cgtccagacg accatcaaga ggacgatgac gactgaaacg
     6661 ggctttagct gtggcatcgt gatgtaccgg aatttccccc atcgacccgc gccgtcggtc
     6721 tctgcggcct cgtagaggtg ctctggaatc gactgcaagc ccgcatagag cataatcgcc
     6781 gcccacggga agttctgcca cgtccacacg gcggtaatcg cgagtatcga ccgcgggccg
     6841 atgagccaga agaacgaccc gtcgatgagc ccgaccgacc gaagaatgtg gttaatcatc
     6901 cccgtgtcgg tgcggaacat catctgccag gtcagaacgg tcacgaccgc gggcgcaatc
     6961 cacggcacca acacgagcgt ccgagcggcg agtttccctc tgaagtctct gttcaaaagc
     7021 agggccgtcg ccaacccgag cgtgtagatg cccatgacgg acccgaccgt gaagatgagc
     7081 gtctgtcgga gtgaggtcca gaactcagca ccgacgatag tgttcgggtt gaataccttg
     7141 gcgtagtttt cgaagccgac gattggcgca ttccaccagt tcgacacgta ggccgcatcg
     7201 agttggacga aactgatgta gaacccccag atgatgggca ggaaatggat gagtcccatc
     7261 atcacaaacg ccggcaagag gagtttgtag gcgaatcgtg tatcgtcgct gagtctgggt
     7321 agtcgagcct gtacccagtt cgggacggct ctggtgatac cacttctggc acgctctaac
     7381 atgtgtcatc acttctcaat tggttcatat atatgttctc aaattctgga gggtaattgg
     7441 gtatcctgac actgtcagtc gagacccatt catcggggac gctatcgtct cgtcgcgtgt
     7501 tgcgttgtct cgcgtcgtct cgtcgctacc gcgttagttt tcgctcagga cgttgtttgc
     7561 ctgctgtacc gccttgtcga gtgcggcttt cgtgtcgcct tcgctccagt cgccgctgac
     7621 acctttcgtg aggatatcgg tcacggcgtt cttgatcgtt ccttcgactt cgccccagcc
     7681 gatgacctgt gggaacgtct tcgcacccgg aagcacctcg tcggagaact tctggtacag
     7741 cggtccggag aactgctctt ggtcgaagcc gctttttatc gtcggcagga agccggtcat
     7801 cgaggcgacg tcggcgttga cggcgggtct catcaggtac ttgagccact tggcggcttc
     7861 gtccggatag tccgtccacg ggtggatacc gacgaggttg accccgtaga acgttgcgga
     7921 ctgcccgttc ggacccgctg gcggtttgta cactgccatc gagtcgcggg ttgcgtcccc
     7981 ttcggagacg accttatcga ctgtgttgag tgcactccac gttcccgcga tgcgcttgtt
     8041 gatgaaggca ctgtcgcggg cgggaccgtc ccactcggcg gacgccttcg gggcgacctc
     8101 atattccgtc gcgaggtctt tgtagaagtt gagtgctttg acggcgcttt cgctgttgaa
     8161 caccgcttcc gatttgtcgt cggagaggag gctcccgccg gcctgccaga cgaacatggc
     8221 gtaaaactgg gtaactgccc agttgttcgc ccccggcagc ccgaacagat gcttttcggg
     8281 gaacgtctct ttgaactgct tgctctgttc gacgagttgg tcccacgacg tcggttggtc
     8341 actgattccg gcttcgtcga gcatgccctg atggaccaag tgtccgcgag gaccccagaa
     8401 ccacgggaag ccggtggtaa tgccatcgta gtttgcgacg ttcgtcggct ggtcgtagac
     8461 gccgtcgagg ctgatcccga gttcaccaag gtccatccat gcgtccgact gcacttgttg
     8521 tggcatccac gtcgatgcga tttcttcgat atccggaccg tcgcggctgg tgatgctgtt
     8581 gagttgtttt tgcttcgcgt tgccccagcc catcgtctcg acttcgacgg cgatgcccgt
     8641 ttcttcttcg aacttcgcgg cgtgtttctc gtagaacttc tcgacgccgg gagttgcgaa
     8701 gtgccgggct tggagggtta cgtcgttact actctgtttc gtcttgttgc caaactgccc
     8761 gagacaaccc gtcaggccag ttgccgttgc cgctccggca cctgcgagaa gctgtctccg
     8821 cgacagattg cgcgtactag cgtcttccat gagacaatac cactatagaa atgacactat
     8881 ttataattca ttgttatgtg tggccgtgtt acatgagttg acgacacacc acgtgacgga
     8941 taatcggcca actgcgccgc caccacgaca agttattaca ccctggtcga aataccgcgc
     9001 tatgaaaatc accgggtacg acctctacga actccctccg cgctggttat tcctcaagat
     9061 agagaccgat gaggggctcg ttggatgggg agagccaatc gtcgaagggc gagcaaaaac
     9121 ggtgaagacg gctgtctcgg agatgcttga cggctacctc gtcggcaagg acccgcttcg
     9181 aatcgaagac cactggcaag cgctgtatcg aagcgggttc taccgtggcg ggccgattct
     9241 tatgagcgca atcgcgggca tcaatcaggc gctgtgggac atcaaaggaa agcactacga
     9301 cgctcccgtc tacgaactcc tcggtggcaa gagccgagac aaaatcagag tgtatcagtg
     9361 ggtcggtggt gaccgtcctg acgatgtcat cgaggaggcc catcggctcg tcgacaccgg
     9421 ctacaccgca ctcaagatgg acgcgacgaa ccagacgcgg cacatcgaaa cggccgcctc
     9481 gatagagcag gtcgtcgacc gaattcggaa ggtcagagag gcggtcgaca acacggtcga
     9541 catcggcgtc gacttccgcg gccgtgtctc gaagtcgatg gcgaagatgc tcactaatcg
     9601 gctctccgac ctggacctca tgttcgtcga agaaccagta cttccggaga acgtcgaata
     9661 tctcccggaa atcgccaccc agtcgcaaat cccaatcgcg acaggcgaac gactctactc
     9721 gcggtgggac ttcaaacagc tctttggcgg aggcgctatc gacctgattc agccagtcgt
     9781 ctcccacgca ggcggtatct ccgagatggt caaactcgca accatggcag aagcgtacga
     9841 tgtcggaatc gctccgaact gtccgctcgg cccgattgca ctcgcggcct cgctacaggt
     9901 cgatacgcac attccgaacc tcgtcgtcca agacaacggg ttcgacattc actcacccga
     9961 ccgcggcccc gcatacgact acctcgaaga cacgagcgtc ttcagcttca aagatggcta
    10021 cctcgacacg ctcgatgagc cggggctcgg tatctcaatc gacgaggaaa ccgtcgaagc
    10081 acgctcgggc gctcacgtcg agtggcacaa cccgacgtgg cggaacgaag acgggagtat
    10141 cactgactgg tagtcgtcct gctgttttct cgccggtccg ccacgaaacc gttaaaccgc
    10201 tcttctccga cctcgtgata tgacagaccg gagccaggta ccgacgctct ccgcgccgaa
    10261 aaaaacgttc gccctcatcg aggagatggc ggaccgtgac gggccggtcc gcgtctcgga
    10321 cctcgctgag gaactcggat tcacgcggag cacgacctac aagcatctcg caacgctacg
    10381 cgaactcgga tacgtcagaa aagtcggcgt ggaatatgcg ctgtcgtatc ggttcgtgtt
    10441 gttcggaacg cgtattcggg ggcgctctcc gttgtaccgc gcctcgaacg aactcatcga
    10501 ccaactcgcc gagacgacaa acgaaacgac gggacttctc gtcaaacagg gttcctacgg
    10561 cgtcaatctc taccaatcga ccagcgaccg ttcggagacg gtcgaaatcg accaacacct
    10621 ccactgtacc gcgccgggga aagcgatact cgcgcacctc acggacgagc aggtcgacca
    10681 cgttgtcgac gctgtcggtc tccccgcgcg cacggacaac accattacag acccgggcgt
    10741 gctcgcagat gagttgacga acgtccgcga gcgcggcatc gccatcgagc gaggagagca
    10801 acaccctgac caaaacgggg ttgcggtcgc tttcgaacac gacaacgagg tagccgccgt
    10861 gtacgtcgtc ggccatgccg accgcttgag tagcaaacga ctcgaagaaa acattcccgg
    10921 gatggtgctc ggaacggttc gacggaccaa agagttgctc tgagtctgcg gtcgcttgcg
    10981 gttaccgttc cgacgggggg acgaactcga cggctgtctt gatctgttct ttgtttcgct
    11041 cgaaggcggc cgacgggtcc gctgccggaa caacttcggt aaccacgtcg tcgatgaacc
    11101 agtccggaag cgacgatacg gtatcgatag ccatctcgaa gtgcgggatg tgagagttga
    11161 cgctcccgac gagcgccttg ttttgcagca ccatctcgcg atggagtcgc ccaccgtcga
    11221 tttcgaactc ccagtcgctc ggaacgccaa ggagtgctcc cacgccgttc ggtgcgagcg
    11281 catcgagaac ctcgaacgcg tgtttcgcgt acccggtggc ctcgatggcg atgtcgacgt
    11341 gtccgtattc ggttggaatc tctggtaccg gtgtctcccg cgaatcaacg taggtcgctc
    11401 cgagtttttc gatgatgtcg atgctcgggt ccggtcggtc tcgccgcccc agacagtaga
    11461 ggtcgtctac gtcgcgggcg agtcgcgcca gcgtcaacag tccgagcggg ccgttcccga
    11521 ggacgagcgc cgactccggt tcccacgaaa acgccgcccg cgtcgcgaac gcgtgttgaa
    11581 tcgccttttc ggcgttgctc atcggttcga cgaggaagcc gtggggagcg agcgactccg
    11641 gaatctccac gaggaactcg gccgcgctcg tgaagtactc agacatatag ccgtgagcgt
    11701 ccacgatacc acgttcgagg tacttcccgt cgggagccat gtccggttcg ccgcgctcga
    11761 agtactcgtt cgtcccgtcc ggcggccgtc gaacggtcgg aatgacgata tcaccttcct
    11821 cgaagcccgt cgtcgtcggg tcgacgacga caccgatggc ttcgtggccg agtatctggt
    11881 agtcgtcacc cggtgggaaa ccaccgtgag ttcccttgat aacctcgtgg tcggtgccgt
    11941 cgacgccaac tctaagcgtc ttgaccagaa cctccccgtc cgctggttcg ggtgtcggaa
    12001 cgtcgatgac ccgaggggat tcctcgccgc gatggacggc tatcgcacgc attacagcat
    12061 cctccgtccg cttcggtcgt ccggtgcgtc gtatctcgcg ctgttcgacc tgcccatcgg
    12121 actgtgccgc atccggtgtc gtgagccggt gtcaccaaca cagggggcgc tcggtaaggc
    12181 aatcatcacg acacacgtca ctgggttggg acaaatacct tcgggtaacc agtagtttcg
    12241 cccgcgcacg acgctccgac gaatcggaga aaagaaattc gatggaccga ggatggtcgt
    12301 gtgctggcag gccagcacgc cgagagtgct gacagccggg tcgaactccg gcgggtcagc
    12361 ggctagctac gagtcctgtc actcgctcgt gaacggagcg aagatggacg agaactcgta
    12421 tggctcttgg tcgatgccgc ttttcacggg cgacacctcg ccggaaccgg ttccgttgtc
    12481 ccggtcgata gaccagaacg aaagtaggcc gatgtcgttg tcctgcgcga aggtgaggac
    12541 ctgtttcgcg tcggcctgcg taaacttccc accgacgttg ttcacgccaa tcatcggcgt
    12601 gattccgacc atgctccagc gttcgccggc cgatttgtcg gggaacagag tgccgaggtc
    12661 atcgtggagg ttgctggccg actgggtcac gatatcgccg ctcggttcga cccacccgta
    12721 gttcatcgtc atgatgttca ccgtatcgat ggtgactccc ttgtcgatgg cgtcctgaag
    12781 cacgtctttg ccctgtgcgg tcagtccctt cgtcgacgtg gggagcgtaa aggagacgct
    12841 gacctcgggg cgtcgctctt gaagcatcgc gagcgcctcg tttcggcgct tgaccgtgct
    12901 catggcgaac gcctcttcgt cgatgtccag gtgcgtcgcg ccgtacgcat cgacgaccgt
    12961 ctcgaagtgg tcggcgagaa ccgccgggtc gtcggttcca tcggcgagat acggccctgc
    13021 cgcgccgccg aaggcgatga tgacctcgcc gccagcagcg tggatgtcgt cgatatagcc
    13081 gccgacggac gactcaccca cgagttggtt cgaatcgccg tcccacgccg gctttccgtc
    13141 cggccctgcg agcacgaatg cgagatggaa gtagttcgtc cctgcttttt tcgcgtggtc
    13201 tatcggtgcc gtctccgaat tcgtcgagac gtggtcgtag ggtgcgaaga cgttcgacgg
    13261 aaggctgcct gttggcgttc cgccgccatc tgacgattcg acggtgacgg tcttgtccgt
    13321 cgtatcggtt gcaccgtctg accccgtaac tgtgagtttg accccgtagg aaccagtcga
    13381 ttcgaacgag tgtgaaactg tcttcccgct cgcactcgcg ccgtcagtga aggaccagtc
    13441 gtaggtatcg actgtaccgg tcgattcgct cgcatcgaac gagaccgacg tccccggcgt
    13501 cacagtcgcg tcgtcgatgg taaacgccgc cgtcagactc tcgtcgtcgc caccgtcatc
    13561 ggggccgact ttggtccagt aggctgaatc cgtagacggt tcggcatttc gggaggcgat
    13621 gtcggcttcc cagatgtaac cctcgtaggt gacgcggtcg cctttctcgt atagcgtcgt
    13681 ttcgtcccac ttcggcgggg actcggccga tactgctgtc gatgctgcgc ccacgccggc
    13741 aaccgacgtg acgagtgctg atacgttccg gagataggtt cggcggttct gtgtcattgt
    13801 tgagtcgtga atgctttctg cgtcattggt tggttgtgaa ggctttctgc gtcattggtt
    13861 ggttgtgaac ggattgaaga gagacgagaa ttcgaacggt tcctgctcga tgagggtgct
    13921 ctcgtagagt ttgtcgcctt tgccgttgtc gcggacgagt tcccagaacg agagcaaccg
    13981 aaggtcgtgg ttctgtgcga agtcgaggac ctgtctggcg tcctcctgat agaatgtccc
    14041 gccgatgtcg ttgacgccga tcatcggcgt gagtccgagc atgctccagc gttcgctggc
    14101 tgatttgttg gggtagaggt cgccgagttg cttgtggacg ctctcggccg cactgatggc
    14161 gttttcggcg ttcggctcga tgtccgcgcc gtagtccatg accatcaggt tgactgcgtc
    14221 gagttcgacg cctttcgaga cagcgtcttc gaggacgaac agcacgtcat tcgacgagtg
    14281 gccggggaga cccgaaggca tcaccggcag agtgtacgaa acgtgcaggt cggggtactc
    14341 gtcttgcaac atgacaagcg cctcgttccg tcgtcgaatc gactcctcgt cgcggctgat
    14401 aagcgactct tcgtcgaagt cgatgtacgt gaggtcgtac gtatccacga ccgtcgcgta
    14461 ggcgtctttc aactcgctcg cactcgtcgt cgcctcggcg aggtacgtcc cgttgagacc
    14521 gccaaaggag acgatgactt cgccgccgtg ttggtcccgg agttcggtga gttgggtgcc
    14581 gacatcgagc cagttgctcg gttcgccgac cttctggctt ccggcccatg ccgggtcgcc
    14641 gtttccatca gcgaggacga acgcgagcgt gaagtacttc gttccggccg cctcgacgtt
    14701 ggctgcgagc gagagttggt cttccagcat catatcgacg tacggggcga agacgctgtc
    14761 cgggattggg ttggcagacg ggacgccgtc ggcgtcgacc gtgaggttcc gcgtcgcatc
    14821 ggcggtgttc ccgtcggcgt cggtcaccgt cagcgagatg gtgtagtcgc cggttgcgtc
    14881 gtacgcgtga gcggtggtaa gccccgtccc cgtcgttccg tcgccgaagt cccactcgta
    14941 gctgctcagg tcgccggtcg acgcgctggc gtcgcaggtg acctcggttc cgggttggac
    15001 gaacgtggca ctcacgtcga acgcggccgt cggggggtct cctgcattgt cggcgggttc
    15061 gattcctttc cacatattcg cgtcggcgct cggttcgtca cctttcgtcc accattttgc
    15121 ctcccagatg tgggcatcgt ggacgacgcg gtcgccgtcg gtgtagaccg tatctgggtc
    15181 ccactgcggg tagtcaccgg ccgctttcac tgactggatt cctgctgtcg agagtcccgc
    15241 aaccccggtc agtcccgcga tggaccggag tatcgagcgt cgattctgtt tcattgattc
    15301 acttgtccgt cgatggcgtc gagaagtgac ccgttgtagt cttgcgacag ttcccagaac
    15361 attacgccgc cgagtccttc cgacttcgcg agtttgacct tctcttcgat ggatgcgggg
    15421 tcgtcgtaac tgatgaatat ccctttttcc tcgttccaga gccacggcac ctgcccctgt
    15481 tcgttgacgt tcttttgcca gccgtcggca ccctcgtagt tctcttcgag gtcgccgtag
    15541 tcgaacgcac cggtgtttgc ttggtcggaa ccgagaaggt ggttccacgt tcctggtggg
    15601 atgacctcgt tttggtactg cgggtcacct tgctgccagt cggacagcga gaaggtgtcc
    15661 caaatcccgt tttcgacctt acagccgcgg ccgtagaacg ggagaccgag tacgaggctg
    15721 gcggggtctt cgaccggttc tccgtaatct tcccactgca tccagtcgac ccagtagcct
    15781 tgttctttcc agatttcgag cgtcgtttcg agggtgtact gctgggcgtc cccggatggt
    15841 gggtagtcgt ccggcgtgcc gtaaatcggg gcgtttagcc cggcagtctc gtgccagacg
    15901 ccggtgaaat cgtacgacat catgtagatt tcgtcgacga cgcgttcgac ctcgcggtgt
    15961 ttgactaacg aggcgttcca gtctgaaccg ccgtttgcga ccgagagata gtacgttcgg
    16021 ccgtcttctt cctcgacggt gtcgagtttg ttccgaacgg ctttgaggag tttgacgtgg
    16081 tttgctggtc cttccgaact tccacactca caggcacccc tgttcggacc ggggtgttcc
    16141 cagtcgatgt cgatgccgtc gaagtcgtac ttccgcatga gtgaaaccgc ggtttcggcg
    16201 aaccgagttc ggttcgcctc gtttgcggcg gcgtcctcga acccgggcga gagtgcccac
    16261 ccaccgatag agagtttgag cgtcgtatcc gcggccggac cctgcttgag gtcggcaaac
    16321 gactggagca gtcctttgtg gtcgacttcg ctgtccggga tgaccacgct tccgtcggat
    16381 ttcacgttga ggaacgcgta cagtacgtcg gtcaccttgt cgaaggggat gtcttcgggg
    16441 tagtactgat agtcctcgtt ccccttccaa ctcggatagt agccgacgac actgaactcg
    16501 tccgacgggg cgttctgcga gacggtgacc tgtttcgatg tcgtatcggt tccgtcctcg
    16561 tttccgacgg tgagtgtgac cgtatactcc ttttccgact cgtaggtgtg tgttacggtc
    16621 tctcccgttc cggtcgctcc gtcgccgaag tcccactcgt aactcgtggg acttccgctg
    16681 gacccgctcg cgtcgaagga aatctcgaca cccggttcga cgtaggtgtc gctcgcggtg
    16741 aatgcggctt ttatgccacc gccgccaccg gcctctccga tttgtttcca catgttcgcg
    16801 tcggtggtcg gctcgtcgcc tttcgtccac cacttggctt cccagatgta gccgttgtga
    16861 gtgacgcggt caccgcccgt atatgccacg tctggctccc acgttggtgg tgtttctgct
    16921 gccgatgcgg ttgcgctcgc gcccgaaagg agtgcgagca gggctgacgt attccgtagg
    16981 tagcttcgtc tgctctgtct catagttggt gtcgcccgtc agtgggtcgt gtaatggtcg
    17041 gaatcaccgt tgtcagaggg tgcagcgttg aactcccgcg gtctctcccg atttttcacg
    17101 tccctcccga cgtgctgacg acagataccg tactgagcat tagttattaa atgttggcac
    17161 tgtctaaatt ttagtatttt gaaaaagaat ttttacagcc gctatctggc gtccctcgcg
    17221 gcgaggggac gccacgatta gtgcacgtac tgcgtgttct gtgcgtttac agacccgtgt
    17281 ggtctgtgtg ctctctgtgt cttagagatg ttcgaggagc gtgtcgagta gcacttcgtt
    17341 tttatcgccc gagaatgccc agaacatcat cccgccgatg tcgttgttga cggcgtagtc
    17401 cgtcttgatg ccgatggact tcggattgtc gtagctgacg agcacgtcgg agttgttcga
    17461 gtatatccac ggtaccttgg ccgtgtcgtc ccagtggtag tcgtactctg agcttggttc
    17521 gaggttcttg ttgatatccc agaactccat gatgccgttg tcttggcccc acgttccgtc
    17581 gggggagcct tcgaaggact ggtacagacc gccgttgtcg ctactcgcga cgttcccgaa
    17641 gctccggccg tagaacggga gacccatcga aagctgggaa ctgtcgaacg cggtgttcgc
    17701 ccagtagctc atcgcggcat cgacgttgaa gtcttccgcc cgtggggacg ggtcgttctc
    17761 cttgaagtac agcggactct ggtggttcgt gtagtcgtcg aaggctccgt ggaagtcgta
    17821 cgtcatgacg ttcacgaagt cgagaagccc ggtgttacgc tggtggtcga gcccgttgtt
    17881 tttcttcggg tcggcggaca gtgcggtcgt cagcaggtac tcttgtccgt cctcctgttc
    17941 ggcagcgtcg agttcggccc gaaccgcatc tagcaggtcg gagtaccgct ttttgtcgcc
    18001 gtcgcggacg atgttccccg actttccgcc accgccggga tactcccagt cgatgtcgag
    18061 accgtcgaag ttgtgctctc gcataatctc gacggcggtc ttcgcgaagc gctgtcgact
    18121 cgcttcggtt tcggccgcgt tcgagaagta cttcgagtcg ttccagccac cgatagagaa
    18181 taggaacttg gtcgtcgggt cgtcgacgat ttcgttgaac cctttgtggt cgtgccacga
    18241 ttcgggcttg agaacccggt acgccgcatt ctcgttgata taatcgactg ccccgtcctg
    18301 tttcacggtc aggaaggcgt agttgacgtg tgtgactttg tccagtggga tgtcgccggg
    18361 ggtgtactcg cggtcccact gcgcccactg catgtagtac ccgacgacgc gcttgtcggt
    18421 cggcattccg ccgtcgctcg cagtgatgac cttcgtcgtc gagccagtcg cgccagagtc
    18481 gtccgttacg gtcaacttga ccgtgtactc gcccaccgaa tcgtacgtgt gagagacgac
    18541 tttgccggac ccagtcgctc cgtcgccgaa gtcccaatcg tactcggtag cggtgtcgcc
    18601 cgacccactc gcatcgaact cgactgtttg cccggggttg atgacgaggt cgcttgcggt
    18661 gaacgacgct ttcggaccgt ctccgccgtc gtcgaccggc tcgatttgct tccagacgct
    18721 cgcgtccgta ctcggctcgg taccgcgggt ccaccacttg gcttcccaga tgtagccgtt
    18781 gtaggtgacg cggtcgccgc cggtgtaggt tgcttcaggg tcccatttgg ggggtgtctc
    18841 tgctgctacg gccgtacccg cgccaccgag gagcgcaagc agggccgacg tgttccgtag
    18901 gtagtctcgt ctgctctgtt tcat
//
