LOCUS       CP000303                6862 bp    DNA     linear   BCT 31-JAN-2014
DEFINITION  Bifidobacterium breve UCC2003, complete genome.
ACCESSION   CP000303
VERSION     CP000303.1
DBLINK      BioProject: PRJNA13487
            BioSample: SAMN02604112
KEYWORDS    .
SOURCE      Bifidobacterium breve UCC2003
  ORGANISM  Bifidobacterium breve UCC2003
            Bacteria; Actinobacteria; Bifidobacteriales; Bifidobacteriaceae;
            Bifidobacterium.
REFERENCE   1  (bases 1 to 6862)
  AUTHORS   O'Connell Motherway,M., Zomer,A., Leahy,S.C., Reunanen,J.,
            Bottacini,F., Claesson,M.J., O'Brien,F., Flynn,K., Casey,P.G.,
            Moreno Munoz,J.A., Kearney,B., Houston,A.M., O'Mahony,C.,
            Higgins,D.G., Shanahan,F., Palva,A., de Vos,W.M., Fitzgerald,G.F.,
            Ventura,M., O'Toole,P.W. and van Sinderen,D.
  TITLE     Functional genome analysis of Bifidobacterium breve UCC2003 reveals
            type IVb tight adherence (Tad) pili as an essential and conserved
            host-colonization factor
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. (2011) In press
   PUBMED   21690406
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 6862)
  AUTHORS   O'Connell Motherway,M., Zomer,A., Leahy,S., Reunanen,J.,
            Bottacini,F., Claesson,M., O'Brien,F., O'Flynn,K., Casey,P.,
            Moreno-Munoz,J., Higgins,D.G., Shanahan,F., de Vos,W.,
            Fitzgerald,G.F., Ventura,M., O'Toole,P. and van Sinderen,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-MAR-2006) Department of Microbiology, Alimentary
            Pharmabiotic Centre, University College Cork, College Road, Cork,
            Munster, Ireland
COMMENT     Source DNA or strain is available from Douwe van Sinderen,
            d.vansinderen@ucc.ie.
FEATURES             Location/Qualifiers
     source          1..6862
                     /organism="Bifidobacterium breve UCC2003"
                     /mol_type="genomic DNA"
                     /strain="UCC2003"
                     /db_xref="taxon:326426"
     gene            complement(1..1863)
                     /locus_tag="Bbr_1856"
     CDS             complement(1..1863)
                     /locus_tag="Bbr_1856"
                     /EC_number="2.4.1.82"
                     /EC_number="3.2.1.22"
                     /codon_start=1
                     /transl_table=11
                     /product="GH36"
                     /protein_id="ABE96518.1"
                     /translation="MIAETCPITVRTVTAHLDTGRAVYGEQASAICELPVEAVTIVPES
                     CEDECTSSAGIQGDAQVRLWRIDVNAHAPQPKDRAAAFQEQQAFEPHHAIDVSLTMASV
                     DSGNDDTMLALYQHKEWWMRPTWVRTPFELPERTQLLLCRNNDAEDAEWLVLVAICGTD
                     IRADFSGQPATESDDTALRLVLSSNRVGRTTLCDTAAYIACASDPYMAIRAATQTAARQ
                     LGIRTRKERPFPDALTGLGWCTWDSLGRDVNEQAIVNKMEEFQAKHVPISWVLIDDGWS
                     NTDRTKETLIDFGADRQRFPHGLAHTIALLKTHYGVRSVGVWQAFQGYWNGLDESGVAA
                     ASCPTAITTTANGCLIPGSRAEQPAQFWDAWDGELAEAGVDFVKVDSQSSTSVMVRGAE
                     SYGEATWGRHQALDEVTSRRFGGALINCMGMAPEDYWHRPSSPITRSSDDYLPHNPDSL
                     GEHLIQNAYCALLMGELYHCDWDMFWTEHPHARVHAVLRLLSGGPVYCSDACGHTDAAV
                     LRDLLAEDGTLPRPDEPARPVIASLLNDPEHAGYALGVTARFGAEQVIAFVGLRRQPQI
                     GIITASGRSCRIIDDHGATIDMNPGETHTCEIEYGQLRVFRVQS"
     gene            complement(1895..3565)
                     /locus_tag="Bbr_1857"
     CDS             complement(1895..3565)
                     /locus_tag="Bbr_1857"
                     /EC_number="3.2.1.20"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q07837|8.A.9.1.2"
                     /protein_id="ABE96519.1"
                     /translation="MTFTNNDWWRDAVIYQIYPRSFSDANGDGNGDLQGVIDRLDYLQA
                     LGVDALWLSPFYPSPLADGGYDVADYCDVDPRLGTLDQFDELVAKAHERGIGIIVDIVP
                     NHTSDQHRWFQEALAQGPESETAQRYVFRQGKGEHGELPPTNWLSNFGGSAWESCGDGW
                     YYLHLFAKEQPDLNWDNPEVRHEFLRVLTFWCDRGVDGFRIDVSHGLAKDLREPLRDRI
                     DPTLMSPQATDGSDPLWDRDAVHDIYREWRDLFNQYMPAKYAVGESWSPFTTRIFQYAK
                     PDELGAVFDFSMSKAAWNREEYRTTIERTHRYALAAETAPTWVLGNHDVPRIASRLGLP
                     SGANIEQWVTSNGTNPPIDPALAARRARAAALVMLGLPGTAFVYQGEELGLPEDFDLTE
                     DEIQDPNWERSGHYFKGRDGCRVPLPWQSDGPAFGFNATGALWLPQPAWFAQYAANRQI
                     GDGASVLHLYRAAIALRKQWVDNGTDFQFSWLTNEECPAPLLGWRLPSGMVVMANFSDS
                     QPVALPQPMTVLLVSDATVQANTQVESVPPAATVWALPA"
     gene            complement(3666..4490)
                     /locus_tag="Bbr_1858"
     CDS             complement(3666..4490)
                     /locus_tag="Bbr_1858"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q8RJU8|3.A.1.1.18"
                     /protein_id="ABE96520.1"
                     /translation="MQQSKAVRITGTAMLALTVLFCVLPFLSMLSAALQPQGSMPEGIQ
                     FTAHPHWENFIDAWNMANITPLLLNSCILVIVVVPCVVIFCSLGGYAFAQLKVPCKGLI
                     YVLFLVGLTIPFETLVTPLYYEISGMGLLNTRLALILPLIGLNIPFGIVWMRSCFEQMP
                     RDLIEAASIDGAGHLRTFRSIQLPLALPAISSLGILTFLATWNQFLLAVVLENDPNKRT
                     MAGALQSFVGQYQTDVVLLNAGALLIMAPTMILFIFLQRYFIRAMLAGSVKG"
     gene            complement(4493..5533)
                     /locus_tag="Bbr_1859"
     CDS             complement(4493..5533)
                     /locus_tag="Bbr_1859"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q7WWQ9|3.A.1.1.20"
                     /protein_id="ABE96521.1"
                     /translation="MHLPGGVFFPFSRSAWFLPIARTTLCAMFDSQFTPNQQSVVTIMD
                     SHKAAKAVKPKRNMSLGLVSLLFLAPALVFYIAFELWPIIQTIWYSFYEWNGIDASTFI
                     GVENYITVFTDPDLYGSILHSFYLIIFFSIIPIVLGLIIAVLIKDMKSKVGRSFAQVCL
                     FLPRVIPGAAAGVAWTWMLADKGTANQLLRAVGLGDFAHVWLGDQSTSLNAVGVIGFWL
                     QLGFCVVLLLSGIGGIDQSLYEAASLDGAGWWRQLFSITLPGLRGQIGVCLTMTIISAL
                     ASFDVVYMSTQGGPGTSTMVPGVQVYRLAFTQQSVGLASALAVTLMILVLLVVGPLQRL
                     VNGKEQ"
     gene            complement(5537..6862)
                     /locus_tag="Bbr_1860"
     CDS             complement(5537..6862)
                     /locus_tag="Bbr_1860"
                     /codon_start=1
                     /transl_table=11
                     /product="STP|SBP_bac_1"
                     /protein_id="ABE96522.1"
                     /translation="MRIERTAKTVIAGLMSVACLASVAACGPGSSSNKANTETEAVSTD
                     LGDTKYELKLWDGAGLKTFDDQLIEAFQKKYPNITIKATYDPDNTSQQNGPRIISAADT
                     PDIARITDINSAVRGNHVVNLDAYADAYGWKLPDSQTQVYRVGSDGKIGSGSLYAVPDG
                     VSMTGLYWNKKVAKELGITEAPATVEELEADMKKASDAGKLAMMMPAKEGGTSYIYQAL
                     LTNYEGRDTVQDWIIQKDGATFNTDGAVKAAQKIKDWQDAGYFSSDALALDGSTALSRF
                     CNGEALFFPSGSWYSASINDALGDDAGWIAFPGEKADSGSAAANAVTAFGIPANAKNKN
                     AAAAFLDFLQSDEARQIAVDNGYPPVGEGETPSTDNQLLGQVLTAYEGLVKTGNTTDYI
                     NNATAGMQASAIIPGFQSLIDGTMTPKAFVESIQAQYEKEAK"
ORIGIN
        1 tcatgattgc acccggaaaa cacgcagttg gccgtactcg atctcgcaag tatgggtttc
       61 ccccggattc atatcaatcg tcgcaccatg gtcatcgatg atgcggcaag agcgaccgct
      121 agccgtaatg atgccgattt gtggctgccg gcgtaatccg acgaaagcga tgacctgttc
      181 tgcgccgaat cttgctgtga caccgagcgc atagcccgca tgttcggggt cattgagcag
      241 tgacgcaatg actggtcggg ccggctcatc aggacgcggt aatgtaccat cttcggcaag
      301 taaatcacgc aagacagccg catcagtgtg accgcaggca tcggaacaat acactggccc
      361 gccgctaagc aatcggagca cggcatggac tcgcgcatgg ggatgctccg tccagaacat
      421 gtcccaatca cagtggtaca gctcccccat cagcagtgca cagtatgcgt tctggataag
      481 gtgttcgccc agcgaatcag gattgtgcgg cagatagtcg tcgctactac gggtgattgg
      541 cgatgaagga cgatgccaat aatcctccgg tgccatgccc atgcagttaa tcaatgcgcc
      601 gccgaatcgt cgtgaggtca cttcatcaag cgcctgatgg cgtccccagg tggcttcacc
      661 gtaactttcg gcgccacgaa ccattactga cgtagaactt tgcgaatcca ctttgacgaa
      721 atcgacgccg gcttcggcga gttcgccgtc ccaggcatcc cagaactgtg cgggttgttc
      781 agcacgactt ccaggaatca ggcaaccatt cgccgtggtg gttattgcgg tcgggcagct
      841 ggccgcggct acacccgact cgtccaaacc attccaatag ccttggaacg cctgccacac
      901 gcctacgctg cgcacgccat agtgcgtttt gagcagcgca atggtgtggg caagcccgtg
      961 ggggaaacgt tggcgatccg cgccaaagtc gatcagggtt tcctttgtgc gatccgtgtt
     1021 ggaccaaccg tcatcgataa gcacccagga aatgggcaca tgcttggcct ggaactcctc
     1081 catcttgttg acgatggcct gctcgttgac atctcgcccc aatgaatccc aagtacacca
     1141 tcccaacccg gtgagcgcat ccgggaatgg acgctcctta cgggtgcgaa tacccagctg
     1201 gcgtgctgcc gtttgtgtgg cagctcgaat ggccatatac gggtcggatg cgcaagcgat
     1261 atatgcggca gtgtcacata gagtcgtgcg accaacccgg ttggaagaca gcacgagccg
     1321 caaagccgtg tcatcagatt ctgttgcggg ctgcccgctg aaatcagccc gaatatccgt
     1381 gccgcagata gcgaccaaca ctagccactc ggcatcttcg gcatcgttgt tgcgacataa
     1441 caataactgc gtgcgttcag gcagttcaaa tggtgtacgc acccaggtcg ggcgcatcca
     1501 ccactccttg tgctggtata gcgccagcat ggtgtcatcg ttgccgctgt cgacgctggc
     1561 catggtgagc gacacgtcaa tcgcatggtg gggctcaaac gcttgttgtt cctgaaaagc
     1621 agcggcgcgg tccttgggct ggggtgcatg cgcgttcaca tcgatacgcc agagtcgcac
     1681 ctgagcatca ccctggatac ccgcactgga cgtgcactcg tcttcgcatg attcgggaac
     1741 gatcgtgacg gcttctaccg gcagttcaca gattgccgaa gcctgttcgc catagacggc
     1801 acgaccggta tcaagatggg ccgttaccgt gcgaacggtt attggacagg tttcggcaat
     1861 cattggcgta actccttggt gttcttcaat gagattatgc tggcaaggcc cagacggtag
     1921 cagctggagg aacgctctcg acctgagtgt tcgcctgcac agtcgcatca gacacaagta
     1981 gcacggtcat cggctgcggc aaggcgactg gttgactgtc agagaagttc gccatcacaa
     2041 ccatgccgga cggcaagcgc caaccaagca gcggcgccgg acactcttcg ttggtaagcc
     2101 acgagaactg gaagtccgtg ccgttgtcca cccactgttt gcgcaatgcg atggcagcac
     2161 gatacaggtg caggacggaa gccccgtcac caatctgacg attagcggca tactgcgcaa
     2221 accatgccgg ctggggcagc cacaaagcac cggtggcatt gaagccgaac gccgggccgt
     2281 ctgactgcca cggcagcggt acgcggcaac cgtcgcgccc cttgaaataa tgaccggaac
     2341 gttcccaatt gggatcctga atttcatctt cggtcaaatc aaagtcctca ggcaaaccaa
     2401 gctcttcacc ctgatacaca aaggcggtac ctggcaggcc gagcatcacc agcgctgctg
     2461 cacgggcacg acgagcggcg agcgcggggt caatcggcgg attcgtgccg ttggacgtca
     2521 cccactgctc gatgtttgca ccgctcggca gtccgagacg cgaggcgata cgtggcacat
     2581 cgtggttgcc gagcacccag gtgggggcgg tttcggcagc gagagcatag cgatgcgtgc
     2641 gctcaatcgt ggtgcggtat tcttcgcgat tccaggcggc ctttgacatg gagaagtcaa
     2701 atacggcacc aagttcatca ggcttggcgt attggaaaat acgggtggtg aatggcgacc
     2761 acgattcgcc gaccgcatac ttggctggca tgtactgatt gaacaggtcg cgccattcac
     2821 ggtagatatc atgcacggcg tcgcggtccc agagcggatc ggaaccatcg gtagcctgtg
     2881 gagacatcag tgtcgggtcg atacggtcgc gcagcggctc acgcaggtct ttggccagac
     2941 cgtgcgagac atcgatgcgg aaaccgtcca cgccgcgatc gcaccagaat gtgagtacac
     3001 gcaggaactc atgccgcacc tcgggattgt cccaattgag gtccggctgc tccttggcga
     3061 acagatgcag gtagtaccag ccgtctccac acgactccca tgcggaaccg ccgaagttac
     3121 tcagccagtt ggtaggcggc aattcgccgt gctccccctt gccctgccgg aacacatacc
     3181 gttgtgccgt ttccgattcc ggaccttgag ccagggcctc ttggaaccaa cggtgctgat
     3241 cggacgtgtg gttcggcacg atgtccacga tgatgccgat accgcgttcg tgcgctttgg
     3301 ccactaattc gtcgaactga tcgagtgtgc caaggcgggg atccacatcg caatagtcgg
     3361 caacatcata acctccatcc gccagcggcg atggatagaa tggagaaagc cagagcgcgt
     3421 ccaccccgag cgcctgcaga tagtcgagac gatcgatcac gccttggaga tcaccgttgc
     3481 cgtctccatt ggcatcgctg aatgagcggg ggtaaatctg gtagatgacg gcgtcgcgcc
     3541 accagtcatt gttggtgaaa gtcatatcgt tcccctgtcc gattgctcgg tacgtatggt
     3601 tttaccagta tggccgcacg aaacactgtt ccggcggcca taccatacat cctcttgcct
     3661 tcggatcagc ccttgaccga gccggcaagc atggcgcgga tgaagtagcg ctggaggaag
     3721 atgaacagga tcatcgtcgg tgccatgatg agcagtgcgc ccgcgttgag cagcaccacg
     3781 tcggtctgat actggccaac gaacgactgt agggcacctg ccatcgtgcg cttgttcggg
     3841 tcgttctcca acaccacagc caacaggaac tggttccagg tggccaggaa ggtcagaata
     3901 ccgagcgagg agatggctgg cagtgccaac ggcagctgaa tggaacggaa cgtgcgcaga
     3961 tggcctgcac catcgatgga tgcggcttcg atcagatcac gcggcatctg ctcgaagcag
     4021 gagcgcatcc acacaatacc gaacggaata ttcaggccga tgagcggcag gatcagggca
     4081 agacgggtat tcagcaagcc catgccgctg atctcgtagt acagcggagt gaccaaggtt
     4141 tcgaacggaa tggtcagacc gacgaggaac agcacgtaga tcaggccctt gcacggcacc
     4201 ttgagctgag cgaaggcata accaccgagc gagcagaaga tcaccacgca gggcacgacc
     4261 acaatcacca gaatgcagct gttgagcagc agcggggtga tgtttgccat gttccaggcg
     4321 tcgatgaagt tctcccagtg cgggtgggca gtgaactgga taccttcggg catggaacct
     4381 tgcggctgca atgccgcgga gagcatgctc aagaacggca gtacgcagaa gaggacggtc
     4441 agagcgagca tcgccgtgcc ggtgatgcga acggctttgg attgctgcat ggtcactgct
     4501 cctttccatt gaccagacgc tgcagaggtc cgacgaccag cagcaccaga atcatcaggg
     4561 tgacggcgag cgcggaggcc aagccaacgc tctgctgggt gaaggccaag cggtagacct
     4621 gcacgccggg caccatggtg gaggtgccgg ggccgccctg agtggacatg tacaccacgt
     4681 cgaagctggc gagcgcggag atgatggtca tggtcaggca tacgccgatt tggccgcgca
     4741 gaccaggcaa cgtgatggag aagagctgac gccaccagcc ggcaccgtca agacttgctg
     4801 cctcgtacag ggactggtcg atgccgccga tgcccgagag caggagcacc acacagaagc
     4861 cgagctgcaa ccagaaacca atcacgccta ccgcgttcag ggaggtggat tggtcgccga
     4921 gccacacgtg ggcgaagtcg ccgaggccta ctgcgcgcag cagctgattg gcggtgccct
     4981 tgtcggccag catccaggtc caggccacac cggctgcagc gcctgggata acgcgcggca
     5041 ggaacaggca aacctgcgcg aaggaacgac cgaccttgga cttcatgtct ttgatgagca
     5101 cggcaatgat caggccgagc acaatcggga tgatggagaa gaagatgatc aggtagaagg
     5161 agtgcagaat cgatccgtac agatcggggt cggtgaacac ggtgatgtag ttttcgacac
     5221 cgatgaaggt gctagcatcg ataccgttcc actcgtagaa cgagtaccag atggtctgaa
     5281 tgatcggcca caactcgaag gcgatgtaga acacaagcgc cggagcgagg aaaagcaggc
     5341 tgaccagacc gagggacata ttgcgcttgg gcttgaccgc cttggctgcc ttatgggaat
     5401 ccatgattgt caccacgctt tgctggtttg gtgtgaactg ggaatcgaac atcgcacaca
     5461 acgtcgtgcg cgcgatggga aggaaccagg cggagcggga aaaagggaag aacactccgc
     5521 ccggtaagtg caagggttac ttggcttcct tctcgtactg agcctgaatg gattcgacga
     5581 atgccttggg ggtcatcgtg ccgtcaatca gggactggaa gccggggata atggcgctgg
     5641 cctgcatacc tgcggtggcg ttgttgatgt agtcggtggt gttaccggtc ttcaccagac
     5701 cttcgtaggc ggtaaggacc tggccgagaa gctggttatc ggtgctcgga gtctcgcctt
     5761 cgccgaccgg cgggtagccg ttgtcaactg cgatctggcg ggcttcgtcg gactggagga
     5821 agtcgaggaa ggcggctgca gcgttcttgt tcttggcgtt ggccgggata ccgaaagcgg
     5881 tcacggcgtt ggctgcggca gaaccggaat cggccttttc gccggggaag gcgatccagc
     5941 cggcgtcatc gccaagtgca tcgttgatgg aggcggagta ccagctgccg gaggggaaga
     6001 acagggcttc gccgttgcag aagcggctca gtgcagtgga accgtcaagg gcgagcgcgt
     6061 cggaggagaa gtaaccggca tcctgccagt ccttgatctt ctgtgcagcc ttcacggcac
     6121 cgtcggtgtt gaaggtggcg ccatccttct ggataatcca atcctgcacg gtatcgcgac
     6181 cctcatagtt ggtgagcaat gcctggtaga tgtaggaagt gccgccttcc ttggccggca
     6241 tcatcatggc gagcttgcca gcgtcggagg ccttcttcat atcggcctcg agctcttcga
     6301 cagtggccgg agcctcggtg atgccgagtt ccttggcgac tttcttgttc cagtacaggc
     6361 cggtcatcga gacaccgtcc ggcactgcgt agaggctgcc ggaaccgatc ttaccgtcgg
     6421 agcccacgcg gtagacctga gtctgggaat ccggcagctt ccaaccgtaa gcatcggcgt
     6481 aagcgtcaag attgacgaca tggttgccac gcacagcgga gttgatgtcg gtgatacggg
     6541 caatgtccgg ggtgtcggcg gcggagatga tgcgcgggcc attctgctgg gaggtgttgt
     6601 ccggatcgta ggtggccttg atggtgatgt tcgggtactt cttctggaag gcttcgatca
     6661 gctggtcatc aaaggtcttc aggccagcgc cgtcccacag cttgagctca tacttggtat
     6721 cgccaagatc agtgctcacc gcttcggttt cggtgttggc tttgttgctg gacgagcccg
     6781 ggccgcaagc ggcgacggat gccaggcatg ccacagacat cagaccggca ataacggttt
     6841 tggcggttcg ttcgatcctc at
//
