LOCUS       AB011415               14852 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Sphingomonas sp. cat, mdr, aly, ccpA, algS, algM1, algM2, algQ1,
            algQ2, oal genes for catalase, multidrug resistant protein, alginate
            lyase, transcriptional regulator, AlgS, AlgM1, AlgM2, AlgQ1, AlgQ2,
            oligo alginate lyase, complete and partial cds.
ACCESSION   AB011415
VERSION     AB011415.1
KEYWORDS    algS; cat; catalase; oligo alginate lyase; oal; AlgQ2; AlgQ1; algM2;
            AlgM1; multidrug resistant protein; alginate lyase.
SOURCE      Sphingomonas sp
  ORGANISM  Sphingomonas sp.
            Bacteria; Proteobacteria; Alphaproteobacteria; Sphingomonadales;
            Sphingomonadaceae; Sphingomonas.
REFERENCE   1
  AUTHORS   Momma,K., Okamoto,M., Mishima,Y., Mori,S., Hashimoto,W. and
            Murata,K.
  TITLE     A novel bacterial ATP-binding cassette transporter system that
            allows uptake of macromolecules
  JOURNAL   J. Bacteriol. 182 (14), 3998-4004 (2000)
   PUBMED   10869078
REFERENCE   2  (bases 1 to 14852)
  AUTHORS   Murata,K., Momma,K. and Hashimoto,W.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-FEB-1998) Kousaku Murata, Kyoto University, Research
            Institute for Food Sciencce; Gokasho, Uji, Kyoto 611-0011, Japan
            (E-mail:momma@food2.food.kyoto-u.ac.jp, Tel:81-774-38-3768)
COMMENT     Sequence updated (28-Feb-2000).
FEATURES             Location/Qualifiers
     source          1..14852
                     /organism="Sphingomonas sp."
                     /mol_type="genomic DNA"
                     /strain="A1"
                     /db_xref="taxon:28214"
     gene            complement(<1..624)
                     /gene="cat"
     CDS             complement(<1..624)
                     /gene="cat"
                     /note="putative"
                     /codon_start=1
                     /transl_table=11
                     /product="STP|peroxidase"
                     /protein_id="BAB03310.1"
                     /translation="MSEKTEAKCPFSHAAMTGTTNRDWWPNQLRLDLLHQHSSKSDPMG
                     EDFDYIKEFNSLDLAEVKKDLAAVMTNSQDWWPADFGHYGGLFIRMAWHAAGTYRIGDG
                     RGGAGRGQQRFAPLNSWPDNVSLDKARRLIWPVKQKYGRKISWADLIVLTGNVALETMG
                     FKTFGFGGGRKDTWEPDQDVYWGRETTWLGGDVRYAHGSEGVDKL"
     gene            complement(1219..2382)
                     /gene="mdr"
     CDS             complement(1219..2382)
                     /gene="mdr"
                     /note="putative"
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug resistant protein"
                     /protein_id="BAB03311.1"
                     /translation="MRRLPPIFALLAMSLMAHVTMSGGRVSASLFALQHNDSNFMAGLA
                     YGMYSLLPALASIHIGRWVDRAGPRRVMNTSLVVMMCGLALPAMWPNLPTVLISAMFGG
                     FGFSSYLLAANVAVSFMPVQHSSERVGMLAWLQIGTSISAVFGPSIAGALIDHAGYRAV
                     FAFMAVTVGIGFVLSRRIELYEGGERAKKHASVAAVLGEVASTPALLRIYLIALALSLA
                     WDGFSFMAPVLGHERGYTASQVGIVLSTFACGTLVTRAALPWLSRRLPEWRMLSVACAV
                     TATVFLVLPIAQSVFLHAALGFVYGLSAGVGQPNILNLIYHSMPPEKAGQGVGLRSMIG
                     GISGLGGPWLFGIIASMLSAAPVFLLIGCVMGSASWQAHRAASATKD"
     gene            complement(2533..4458)
                     /gene="aly"
     CDS             complement(2533..4458)
                     /gene="aly"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /codon_start=1
                     /transl_table=11
                     /product="PL7|PL5"
                     /protein_id="BAB03312.1"
                     /translation="MPLACLATTRVGAAREKSGDSSMFDIPFPGHGRRLAVAALAFAGC
                     AFAGSLQAHPFDQAVVKDPTASYVDVKARRTFLQSGQLDDRLKAALPKEYDCTTEATPN
                     PQQGEMVIPRRYLSGNHGPVNPDYEPVVTLYRDFEKISATLGNLYVATGKPVYATCLLN
                     MLDKWAKADALLNYDPKSQSWYQVEWSAATAAFALSTMMAEPNVDTAQRERVVKWLNRV
                     ARHQTSFPGGDTSCCNNHSYWRGQEATIIGVISKDDELFRWGLGRYVQAMGLINEDGSF
                     VHEMTRHEQSLHYQNYAMLPLTMIAETASRQGIDLYAYKENGRDIHSARKFVFAAVKNP
                     DLIKKYASEPQDTRAFKPGRGDLNWIEYQRARFGFADELGFMTVPIFDPRTGGSGTLLA
                     YKPQGAAAQAPVSAPAAAHSSIDLSKWKLQIPVDPIDVATRDLLKGYQDKYFYVDKDGS
                     LAFWCPASGFKTTANTKYPRSELREMLDPDNHAVNWGWQGTHEMNLRGAVMHVSPSGKT
                     IVMQIHAVMPDGSNAPPLVKGQFYKNTLDFLVKNSAAGGKDTHYVFEGIELGKPYDAQI
                     KVVDGVLSMTVNGQTKTVDFVAKDAGWKDLKFYFKAGNYLQDRQADGSDTSALVKLYKL
                     DVKHSS"
     gene            complement(4500..5561)
                     /gene="ccpA"
     CDS             complement(4500..5561)
                     /gene="ccpA"
                     /note="putative"
                     /codon_start=1
                     /transl_table=11
                     /product="DBD-Pfam|LacI,DBD-SUPERFAMILY|0036955"
                     /protein_id="BAB03313.1"
                     /translation="MEALADYKAGREKPRQSDVAKRAGVSPSTVSKVINGGPGISAELR
                     GRVMQAAQEIGFHIAELRPAAVERGAYRIKLITNYQFLTYDGNYFHAEVIQSVLAECER
                     AGIEIDTVLLDRDHQNDMEKFWDQIRSGAAEGVILVGVDMPPMLEVVRALGVPVVMVNG
                     NDPNCQFDSVMPAFRDGSRIATRYLIEQGHRDIVHVTHLYRPLIRRRLDGFREALEEAG
                     LPFSFERNVIDISSGHFSAEQAASVVAERIANGTLNATALFCVSDYTAFGVVQGILRSG
                     KTVPGDYSVASFDDLPLAQLCRPALTSVGVDRRALGRIAVERLLSRLESVEGPTLRIEV
                     GARLTIRDSTRPV"
     gene            5764..6855
                     /gene="algS"
     CDS             5764..6855
                     /gene="algS"
                     /function="ABC-transporter"
                     /function="ATP-binding domain"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q9KWT9|3.A.1.1.10"
                     /protein_id="BAB03314.1"
                     /translation="MVASVSIQNVVKRYDKTTVVHGVSLDIEPGEFVVLVGPSGCGKST
                     TLRMVAGLEEISGGTIRIDGRVINDLAPKDRDVAMVFQNYALYPHLNVRDNISFGLRLK
                     RTKKSVIDAAVKTAADILGLQPLLERKPSDLSGGQRQRVAMGRAIVRDPKVFLFDEPLS
                     NLDAKLRTQMRAEIKRLHQRLGTTVIYVTHDQVEAMTLADRIVVMRDGLIEQIGKPMDL
                     FLHPANTFVASFIGSPPMNLMPARIAVDSTQHVELNGGNRISLLPRAGTHLAPGQEVVF
                     GIRPEDVTLDGVEGSERAQIKATVDIVEPLGSESILHATVGDHSLVVKVGGLNEVHPGD
                     PVTLHVDLTRVHLFDAQSQASIY"
     gene            6950..7924
                     /gene="algM1"
     CDS             6950..7924
                     /gene="algM1"
                     /function="ABC-transporter"
                     /note="membrane protein; putative"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q9KWT8|3.A.1.1.10"
                     /protein_id="BAB03315.1"
                     /translation="MTSATKAQSIPLPAATLDVRSKPLERLWKDIKRDWLLYAMLLPTI
                     IWFLIFLYKPMIGLQMAFKQYSAWKGIAGSPWIGFDHFVTLFQSEQFIRAIKNTLTLSG
                     LSLLFGFPMPILLALMINEVYSKGYRKAVQTIVYLPHFISIVIVAGLVVTFLSPSTGVV
                     NNMLSWIGLDRVYFLTQPEWFRPIYISSNIWKEAGFDSIVYLAAIMSINPALYESAQVD
                     GATRWQMITRITLPCIVPTIAVLLVIRLGHILEVGFEYIILLYQPTTYETADVISTYIY
                     RLGLQGARYDIATAAGIFNAVVALVIVLFANHMSRRITKTGVF"
     gene            7981..8862
                     /gene="algM2"
     CDS             7981..8862
                     /gene="algM2"
                     /function="ABC-transporter"
                     /note="membrane protein; putative"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q9KWT7|3.A.1.1.10"
                     /protein_id="BAB03316.1"
                     /translation="MLATPFYSRSDRIFGIVNAVLLGIFALCALYPIIYIFSMSISSGA
                     AVTQGRVFLLPVDIDFSAYGRVLHDKLFWTSYANTIFYTVFGVVTSLIFIVPGAYALSK
                     PRIRGRRVFGFIIAFTMWFNAGMIPFFLNMRDLGLLDNRFGILIGFACNAFNIILMRNY
                     FESISASFEEAARMDGANDLQILWKVYIPLAKPALATITLLCAISRWNGYFWAMVLLRA
                     EEKIPLQVYLKKTIVDLNVNEEFAGALLTNSYSMETVVGAIIVMSIIPVIIVYPVVQKY
                     FTKGVMLGGVKE"
     gene            8941..10521
                     /gene="algQ1"
     CDS             8941..10521
                     /gene="algQ1"
                     /function="unknown"
                     /note="putative"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q9KWT6|3.A.1.1.10"
                     /protein_id="BAB03317.1"
                     /translation="MKKLVLAMAIGSSALMFAAPSVVAREATWVTEKPLTLKIHMHFRD
                     KWVWDENWPVAREVARLTNVKLVGVANRAATNSQEQFNLMMASGQLPDIVGGDNLKDKF
                     IRYGMEGAFIPLNKLIDQNAPNLKAFFKTHPEVQRAITAPDGNIYYLPYVPDGLVSRGY
                     FIRQDWLDKLHLKTPQTVDELYTVLKAFKEKDPNGNGKADEIPFINRDPEEVFRLVNFW
                     GARSTGSNTWMDFYVENGKIKHPFAEVAFKDGIKHVAQWYKEGLIDPEIFTRKARSREQ
                     TFGNNIGGMTHDWFASTALFNDALSKNIPGFKLVPMAPPINSKGQRWEEDARQIPRPDG
                     WAITATNKNPVETIKLFDFYFGPKGRELSNFGVPGLTYDIKNGKPVYKDTVLKAAQPVN
                     NQMYDIGAQIPIGFWQDYEYERQWTNDVALQGIDMYIKNKYVLPQFTGVNLTVEEREIY
                     DKYWPDVKTYMFEMGQSWVMGTKDPEKTWNDYQQQLKNRGFYQVMIVMQKAYDRQYGGA
                     AKPAQVGAK"
     gene            10668..12218
                     /gene="algQ2"
     CDS             10668..12218
                     /gene="algQ2"
                     /function="unknown"
                     /note="putative"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q9KWT5|3.A.1.1.10"
                     /protein_id="BAB03318.1"
                     /translation="MKKMMLSVAAVATLMAFAAPVATAKEATWVTDKPLTLKIHMHFRD
                     KWVWDENWPVAKESFRLTNVKLQSVANKAATNSQEQFNLMMASGDLPDVVGGDNLKDKF
                     IQYGQEGAFVPLNKLIDQYAPHIKAFFKSHPEVERAIKAPDGNIYFIPYVPDGVVARGY
                     FIREDWLKKLNLKPPQNIDELYTVLKAFKEKDPNGNGKADEVPFIDRHPDEVFRLVNFW
                     GARSSGSDNYMDFYIDNGRVKHPWAETAFRDGMKHVAQWYKEGLIDKEIFTRKARAREQ
                     MFGGNLGGFTHDWFASTMTFNEGLAKTVPGFKLIPIAPPTNSKGQRWEEDSRQKVRPDG
                     WAITVKNKNPVETIKFFDFYFSRPGRDISNFGVPGVTYDIKNGKAVFKDSVLKSPQPVN
                     NQLYDMGAQIPIGFWQDYDYERQWTTPEAQAGIDMYVKGKYVMPGFEGVNMTREERAIY
                     DKYWADVRTYMYEMGQAWVMGTKDVDKTWDEYQRQLKLRGLYQVLQMMQQAYDRQYKN"
     gene            12453..14738
                     /gene="oal"
     CDS             12453..14738
                     /gene="oal"
                     /experiment="experimental evidence, no additional details
                     recorded"
                     /codon_start=1
                     /transl_table=11
                     /product="PL15_1"
                     /protein_id="BAB03319.1"
                     /translation="MKKLEQPQSADMTIRYFPDSDTLTENPPRFLWLPELDSQARYAVR
                     VVSDAGKETVFGDIQHNFFRPDVTLTPGSYTWSYALWDAAAGKVDSDWSSPRSFVLPAD
                     APAVPGMRHKERYAECDMTHPRLWLSQSEATALGKSVATDPDHCKWANFMAKSVTPWMS
                     REIIAEPQPYPNNKRTPALWRKMYIDCQEVIYAIRHLAIAGRVLGDAAMTARAKEWLLA
                     VAAWDVRGPTCRDYNDEAAFRIAAALAWGYDWLHDELSDIERANVRESLTVRTREVANH
                     VINRAKIHIFPYDSHAVRSISSVLVPCSIVLLGEVPEAQKWLDYSIDFYDAIYPPWGGV
                     DGGWAEGPHYWMTAMAYFTEAANLVLKYFKHDLYKRPFFQSTGWFPLYTKAPDTRRACF
                     GDDSTLGDLPCLKVGYNLRQFAGVTGNPYFQWYFEEVCRNDPGTEMEFYNYGWWDLNFD
                     DVQYLHDFPHIEAKAPSDIDTVKYFGDVGWVALQRHMDKPDQHIQFLTKASDFGSISHS
                     HGDQGAFLLYGYGEDLAIQSGYYIGFGTTMHKEWRRLTKSKNAILIDGKGQYSGSNKAE
                     CLKAQGHVLEVGTRNGAHFISLDPTDAYKAEVPYLTRYRRDIHFVHDRFFVIVDDVELE
                     QDGSVQWLMHTFKPCELGSQVFRYHGDKAGLNGEFVYCSSGPVSIENTVSYANIDQSEV
                     EGLPPQSTLVASTGAARRHTLVTLLTPYALSAPLRVFHFNDDQGFSTNLYFQDGNNEMY
                     TITLPKPF"
ORIGIN
        1 aagcttgtcg acgccttcag agccgtgggc gtaacgaacg tcgccgccca gccatgtggt
       61 ttcacgcccc cagtagacgt cctggtcagg ctcccaagtg tctttgcggc cgccgccaaa
      121 accgaaggtt ttgaagccca tggtttcgag cgcgacgttg ccggtcagta cgatcaggtc
      181 ggcccacgaa atcttgcgcc cgtacttttg cttgaccggc cagatcaagc gacgagcctt
      241 gtcgaggctg acgttgtccg gccagctgtt gagcggagcg aatcgttgtt gtccacgccc
      301 tgctccgcca cgaccatcgc cgatgcgata ggtgccggca gcgtgccacg ccatgcgaat
      361 gaacagcccg ccgtaatggc caaagtcagc cggccaccag tcctgcgagt tggtcatgac
      421 agcggccagg tctttcttga cctctgccag atcgaggctg ttgaactcct tgatgtagtc
      481 gaaatcctcg cccatcggat cggacttgga tgagtgttgg tgcaacaggt ccagccgtaa
      541 ctggttgggc caccagtcgc gattcgtggt gccggtcatc gcggcatggc tgaacgggca
      601 cttggcttcg gtcttttcgc tcatttttgc aggcttccta tctcggtagc gtgaagaaaa
      661 gaggctcctt aaaagcaagt cctccaacaa ctggcaaggc cggcgcgcgt actcgatgac
      721 ggcgcggccc tgcatcccgc agggcactct tgctgacaga aaatgtgggc acggaggctg
      781 ccaccgtccg gagagccatc acgtctggta tgtcgtgatc aggatcgacg acggacatga
      841 cgcgatcccg gcccggagta cccgcaaagc ggatgtccta cataaacata gatgccgcta
      901 ctggatatat cagattgcac atggcaatcc actgtattca gtcattcaat cggctttttg
      961 ctggcggctg gattaggccg tctgcctatt gaagtccgca tacacgctgc acgaccgcgc
     1021 gacgcgagcc gcgtgtttgt gcggcacagc agcaaatatt gaacgattca cgatgaaatg
     1081 cgtgcggatg cgcacgctgt tgagtgccgc gactttggcg gatgcctgtc agggcgccac
     1141 gacaagcatc cgagggcagg catttggttc taaacgaaca tgaccgcggc attgcgcacc
     1201 gcagcgactc tggcagcctt aatctttggt tgcgctggct gcccggtgcg cttgccagct
     1261 cgccgagccc atcacgcagc cgatcagcaa gaacaccggt gcggcgctga gcatgctggc
     1321 gatgatgccg aacagccatg ggccaccaag gcccgagatg ccgccgatca tcgaccgcag
     1381 cccgacgccc tgcccggctt tctccggcgg catgctgtga tagataaggt tgagaatgtt
     1441 gggctgaccg acgccagcgg agaggccata cacgaagccc agcgccgcat gcaggaacac
     1501 gctttgcgcg atgggcagca cgaggaagac cgtggccgtc acggcgcagg ccaccgacag
     1561 catgcgccac tcgggcaagc ggcgcgacaa ccacggcaac gccgcgcgag tgaccagcgt
     1621 gccgcatgcg aaggtcgaca gcacgatgcc gacttgcgac gcggtgtagc cgcgctcatg
     1681 cccgagcacg ggcgccatga agctgaatcc atcccacgcc agcgacagcg ccagcgcgat
     1741 cagatagata cgcagcaatg ccggcgtgct ggcgacttcg ccaagcacgg ccgcaacgct
     1801 ggcgtgcttc ttggcgcgtt cgccgccttc gtaaagctcg atgcgtctgg acagcacgaa
     1861 gccgatgccg actgtcaccg ccatgaacgc aaacaccgcg cgataccccg cgtggtcgat
     1921 cagggcgccg gcaatgctgg ggccaaacac agccgagatg gacgtgccga tctgcaacca
     1981 cgcaagcatg cccacgcgtt ccgaactatg ctgcaccggc atgaacgaca cggccacgtt
     2041 ggccgccaga aggtaactgg aaaaaccaaa gcccccgaac atcgccgaga tcagtaccgt
     2101 cggcagattt ggccacatcg ccggcagcgc caggccacac atcatgacaa caaggctggt
     2161 gttcatcacg cggcgcggcc ccgcgcgatc gacccaacgg ccgatgtgga tggaagccag
     2221 cgccggcagc aggctgtaca tgccgtaagc caggcctgcc atgaagttgg aatcgttgtg
     2281 ctggagcgcg aacaacgacg cagacacgcg cccgcccgac atggtgacgt gggccatgag
     2341 cgacatggcg aggagcgcga agatgggagg caggcggcgc atggggtacg gcttcgacag
     2401 caaggtgata cgggaaaacc cgcaagaata ctacgtttgc cagaccgacc cgcggggctg
     2461 gcctgcatgc aatcgctgtg cggggcgaaa cgctgtgcaa aaaagggctc gccgcagcga
     2521 gccccgtttc gatcagctcg agtgctttac gtcgagcttg tacaacttga ccagcgcgct
     2581 ggtgtccgac ccgtcagcct ggcggtcctg caagtaattg cccgccttga aatagaactt
     2641 caggtctttc cagccggcgt ccttggcgac gaaatcgacg gtcttggtct gcccgttgac
     2701 cgtcatcgac aacacaccgt ccaccacttt gatctgcgca tcgtacggct tgcccagttc
     2761 gatgccttcg aacacgtagt gcgtgtcctt gccgccagcg gccgagttct tcacaagaaa
     2821 atccagcgtg ttcttgtaga actgcccctt gaccagcggc ggcgcattcg agccatcggg
     2881 catgacggca tgaatctgca tgacaatggt cttgccactg ggcgacacgt gcatcaccgc
     2941 tccgcgcaga ttcatttcgt gggtgccttg ccagccccaa ttcaccgcgt ggttgtcggg
     3001 atcgagcatt tcgcgcagct cgctgcgcgg gtacttcgtg ttggccgtcg tcttgaaacc
     3061 gctggccgga caccagaagg caagcgagcc atccttgtcg acgtagaagt acttgtcctg
     3121 ataacccttg agcagatcac gcgtggcgac atcgatcggg tcgaccggaa tctgcagctt
     3181 ccacttcgac aggtcgatcg acgaatgcgc cgctgccggg gcggacaccg gcgcctgcgc
     3241 tgccgcgcct tgcggtttgt acgccagcaa agtgcccgaa ccaccggtac gcggatcgaa
     3301 gatcggcacc gtcatgaagc ccagctcatc ggcaaaacca aagcgcgcgc gctggtattc
     3361 gatccagttc aggtcgcccc gccccggctt gaaggcacgc gtatcctgcg gctcggaagc
     3421 gtacttcttg atgaggtccg ggttcttcac cgcagcaaag acaaacttgc gcgctgagtg
     3481 aatatcgcga ccgttctctt tgtacgcgta cagatcgata ccctgacgtg atgccgtttc
     3541 ggcaatcatc gtcagcggca gcatggcgta gttctgatag tgcaaggact gttcgtgacg
     3601 cgtcatttca tgcacgaagc tgccgtcttc attgatcagc cccatcgcct gcacataacg
     3661 gcccagcccc caacggaaga gttcatcgtc cttgctgatc acgccgatga tggtcgcttc
     3721 ctgaccgcgc caatacgagt gattgttgca gcaactcgtg tcgccccccg gaaagctcgt
     3781 ctgatggcgc gccacacggt tgagccactt caccacacgc tcgcgctggg ctgtgtcgac
     3841 gttcggctcg gccatcatcg tcgacagggc aaaggcggcg gtcgccgccg accattcgac
     3901 ttggtaccac gactgcgact tggggtcgta gttgagcaac gcgtcggcct tggcccactt
     3961 gtccagcatg ttcagcagac aagtggcgta caccggcttg cccgtcgcaa cgtagagatt
     4021 tccaagcgtg gcggaaattt tctcgaaatc acgataaagc gtcaccaccg gttcgtagtc
     4081 cggattcacc gggccgtgat tgccggaaag ataacggcgc ggaatgacca tctcgccttg
     4141 ctgcgggtta ggcgttgcct cggtcgtgca gtcgtactcc ttgggcagcg ctgccttgag
     4201 gcggtcatcg agctgcccgc tctgcaagaa ggtacgacgc gccttgacgt cgacatacga
     4261 ggccgtgggg tctttcacga cggcctggtc gaaggggtgt gcctgcaggc tgcccgcgaa
     4321 ggcacaacct gcgaacgcaa gcgcggcgac ggccagacga cggccatgcc ccgggaacgg
     4381 gatgtcaaac atcgaactgt ctccagattt ttcgcgcgca gcccccacgc gcgtcgttgc
     4441 aaggcatgcc aaaggcatgc attcggatag agcattcggg gctgggtgag agcgacacgt
     4501 cagactgggc gcgtactatc gcggatggtc agacgtgcgc cgacttcgat gcgtagcgtc
     4561 gggccttcga cagattcgag acgcgacagc aaccgctcga cagcaatgcg gccaagtgcg
     4621 cgccgatcga caccgaccga agtcagcgcc ggccggcaca actgtgccag cggcaggtcg
     4681 tcgaagctgg ccaccgagta atcgcccggc acggtcttgc ccgagcgcag gatgccctgc
     4741 acgacgccga aagccgtgta gtcggacacg cagaacaacg cggtggcgtt gagcgtgccg
     4801 ttggcgatgc gttcggcgac gacactggct gcctgctcgg ccgaaaagtg cccgctactg
     4861 atgtcgatga cattgcgctc aaaagaaaac ggcagaccgg cctcttccag cgcctcgcgg
     4921 aagccgtcca gccgacgacg gatcaacggc cggtacaggt gcgtgacgtg aacgatgtcg
     4981 cggtgccctt gttcgatcag atagcgcgtg gcgatacggc tgccgtcgcg gaatgccggc
     5041 atcacgctgt cgaactgaca gttgggatcg ttgccgttga ccatcaccac cggcacaccc
     5101 agagcgcgca ccacctcaag catcggcggc atatccacgc caaccagaat caccccctcg
     5161 gctgcgccgc tgcggatctg gtcccagaat ttttccatgt cgttctggtg gtcgcgatca
     5221 agcagaaccg tgtcgatctc gattccggcc cgctcacact ctgccaaaac gctctgaatc
     5281 acctctgcat ggaaataatt tccgtcatag gtcagaaact gataattcgt gatcagtttg
     5341 atgcgatatg caccgcgctc caccgcggca gggcgtagct ctgcgatatg gaaaccaatt
     5401 tcctgggcgg cctgcatcac ccgcccacgc agctccgcgc tgatgcccgg accaccgttg
     5461 atgactttgg acaccgtgct tggcgagacc cccgctcgct tggcaacgtc ggactgacgc
     5521 ggtttctcgc gcccagcctt gtaatctgcc agtgcctcca ttggacttcc tccggccttc
     5581 ctgcgtcgat ttagttgtga gtgcgattct agtttccaga atctttctgg caactgcggg
     5641 ttttccgcaa gtgtggaaat ttctcgaatg tcgaatcatt cgccgcaaca gcaaaaacga
     5701 tttaggtaag cgcttaataa atcgaactag aacggctgct tgaacgggcc aaggaggagc
     5761 aaagtggtag caagcgtcag cattcagaac gtcgtcaagc gttacgacaa gacgactgtg
     5821 gtccatggtg tcagcctgga tatcgaaccg ggtgaattcg tcgtgctggt cggcccttcg
     5881 ggctgcggca agtcgacgac actacgcatg gtggccggtc tggaagaaat cagcggcggc
     5941 acgatcagga tcgacggccg cgtcatcaac gacctcgcgc caaaagatcg cgacgtcgcc
     6001 atggtgttcc agaactacgc gctctacccg cacctgaatg tgcgcgacaa catctccttt
     6061 ggcctgcgcc tgaagcgcac caagaaatcc gtcatcgatg cagccgtgaa gacggccgcc
     6121 gacatcctcg gcctgcaacc gctgctcgaa cgcaagcctt ccgatctttc cggcggtcag
     6181 cgtcaacgcg ttgccatggg ccgcgcgatc gtgcgcgacc cgaaggtctt cctcttcgac
     6241 gaaccgctct ccaacctcga cgccaaactg cgcacgcaga tgcgcgccga aatcaagcgg
     6301 ctgcaccaac gcctgggcac caccgtcatt tatgtgacgc acgatcaggt cgaagccatg
     6361 acattggcag atcgcatcgt ggtcatgcgc gacggtctga tcgaacagat cggcaagccg
     6421 atggacctgt tcctccatcc ggccaatacc ttcgtggcca gcttcattgg ttcgccgccg
     6481 atgaacctga tgccggcacg cattgccgtc gacagcacgc agcacgttga attgaacggt
     6541 ggcaaccgca tcagcctgct gccccgtgca ggcacacatc tggcaccggg tcaggaagtg
     6601 gtgtttggca ttcgcccgga agacgtcacg ctcgacggcg tcgaaggctc cgaacgtgcg
     6661 cagatcaagg ccacggtgga catcgtcgaa ccgctcggtt cggaatcgat cctccacgct
     6721 acggtcggcg atcactcgct ggtggtgaag gtgggcggcc tcaatgaagt acatccgggc
     6781 gatccggtca cgctgcatgt cgatctgaca cgcgtgcacc tgttcgacgc ccagtcacag
     6841 gcctctattt actgacaccc atgacaggcg ggtccggcgc gcaagcgacc gaggcccccg
     6901 gagcacaccc gcacgcacct tacggttgct gcgggcgagg aggagcacca tgacaagcgc
     6961 caccaaggca cagagcatac cgctgcccgc agcgacgctc gacgtgcgtt cgaaaccgct
     7021 cgaacgcctg tggaaagaca tcaaacgcga ctggctgttg tatgccatgt tgctacccac
     7081 catcatctgg ttcctgatct ttctgtacaa gccgatgatc ggcctgcaga tggcgttcaa
     7141 gcagtacagc gcctggaaag gcatcgccgg cagtccgtgg atcgggttcg accacttcgt
     7201 cacgctgttc cagagcgaac agttcattcg cgccatcaag aacacactga ccctgtcggg
     7261 tctgtcgctg ttgttcggct tcccgatgcc gatcctgctg gcgctgatga tcaacgaggt
     7321 ctactcgaag ggttatcgca aggcagtgca gaccatcgtc tatctgcctc acttcatctc
     7381 catcgtgatc gtggccggcc tcgtggtgac attcctgtcg cccagcaccg gcgtggtcaa
     7441 caacatgctg agctggatcg gtctggaccg ggtgtacttc ctgacccagc cggagtggtt
     7501 ccgtccgatc tacatcagct cgaacatctg gaaggaagcg ggcttcgatt cgatcgtgta
     7561 tctggccgcg atcatgagca tcaacccggc gctgtatgaa tcggcacagg tggacggtgc
     7621 cacgcgctgg cagatgatca cgcgcatcac cctgccctgc atcgtcccga ccatcgcggt
     7681 gctgctggtg atccgcctgg gccacatcct ggaagtgggc ttcgagtaca tcatcctgct
     7741 gtaccagccg acgacctacg aaacggccga cgtgatcagt acctacatct atcgtctggg
     7801 cctgcaaggg gcgcgctacg acatcgctac cgccgccggc attttcaatg ccgtggtggc
     7861 cctggtgatc gtgctgttcg ccaaccacat gagccgccgt atcaccaaga ccggcgtgtt
     7921 ctgaccgcag acccgacgca cggcgggcag cccgccccag agaatccaag aggtaccgat
     7981 atgctcgcca cacctttcta tagccgctcc gacaggatct tcggcatcgt caacgccgtc
     8041 ctgctgggca tcttcgcgct ctgtgcgctg tacccgatca tctacatctt ctcgatgtcg
     8101 atcagctcgg gcgcggcggt cacacagggc cgcgtattcc tgcttccggt ggacatcgac
     8161 ttttcggcct acggccgcgt gctccacgac aagctgttct ggacgtcgta tgccaacacc
     8221 attttctaca cggtgttcgg tgtggtcacg agcctgatct tcatcgtgcc cggtgcgtat
     8281 gcgctgtcca agccgcgtat ccgtggccgc cgcgtgttcg gcttcatcat cgccttcacg
     8341 atgtggttca acgcagggat gatcccgttc ttcctgaaca tgcgcgacct cgggctgctc
     8401 gacaaccgct tcggcatctt gatcggcttc gcctgtaacg cgttcaacat catcctgatg
     8461 cgcaactact tcgaatcgat ctcagcatcg ttcgaagagg ccgcacgcat ggatggcgcc
     8521 aatgacctgc agattctgtg gaaggtgtac atcccgctgg ccaagccggc gctggccacc
     8581 atcaccctgc tctgcgccat ctctcgctgg aacggttact tctgggccat ggtgctgctg
     8641 cgcgccgaag agaagatccc gctgcaggtg tacttgaaga agaccatcgt cgatctgaac
     8701 gtcaacgaag agttcgcagg cgccctgctc accaactcgt attcgatgga aaccgtggtg
     8761 ggcgccatca tcgtgatgtc gatcatcccc gtgatcatcg tctacccggt ggtgcagaag
     8821 tacttcacca agggtgtgat gctcggaggc gtaaaagaat aaccaacagg caggacggcg
     8881 cgcggcgtcc ctgtcgcgcg ccggcagtgg gcagtgacat aacggacgga gacaatcatc
     8941 atgaaaaagc tggtactggc catggccatc ggaagttccg cattgatgtt cgcggctccg
     9001 tcggtggtcg cgcgcgaggc gacgtgggtg accgaaaagc cactcacgct caagatccac
     9061 atgcacttcc gcgacaagtg ggtgtgggac gagaactggc cggtggccag agaagtcgcc
     9121 cgcctcacca acgtcaagct cgtcggtgta gccaacaggg ccgctaccaa cagccaggaa
     9181 cagttcaacc tgatgatggc ctcgggccag ttgccggaca tcgtcggcgg cgacaacctg
     9241 aaggacaagt tcatccgcta cgggatggaa ggcgcgttca ttccgctcaa caagttgatc
     9301 gatcagaacg cccccaacct gaaggcattc ttcaagacac accccgaagt ccagcgcgcc
     9361 atcacagcgc cggacggcaa tatctattac ctgccctacg tgccggacgg gctggtgtcg
     9421 cgcgggtact tcatccgcca ggactggctc gacaaactgc atctgaagac cccgcagacc
     9481 gtcgatgagc tgtacaccgt gctcaaggcg ttcaaggaaa aagacccgaa cggcaacggc
     9541 aaggccgatg agattccgtt catcaaccgc gacccggaag aggtcttccg tctcgtgaat
     9601 ttctggggcg ctcgctcgac cggttcgaat acgtggatgg atttctacgt cgagaacggc
     9661 aagatcaagc atccgttcgc cgaagtcgcc ttcaaggacg gcatcaagca cgtggcccag
     9721 tggtacaagg aaggtctcat cgaccccgag atcttcacgc gcaaggcgcg ctcacgcgaa
     9781 cagaccttcg gcaacaacat cggcggcatg acgcatgact ggttcgccag cacggcgctg
     9841 ttcaacgatg cgctgtccaa gaacatcccc ggcttcaagc tcgtgccgat ggcgccgccc
     9901 atcaacagca agggccagcg ttgggaagaa gacgctcgcc agattccgcg ccccgacggc
     9961 tgggcgatca cggcgaccaa caagaacccg gtcgaaacca tcaagctgtt cgacttctac
    10021 ttcgggccga agggccgcga gctgtccaac ttcggcgtac cgggcctgac gtatgacatc
    10081 aagaacggca agccggtcta caaggacacg gtgctgaagg ccgcccagcc ggtgaacaac
    10141 cagatgtacg acatcggcgc gcagattccc atcggcttct ggcaggacta cgagtacgag
    10201 cgtcaatgga ccaacgacgt cgcactccag ggcatcgaca tgtacatcaa gaacaagtac
    10261 gtgctgcccc aattcaccgg cgtcaacctg actgtcgaag agcgcgagat ctacgacaaa
    10321 tactggccgg acgtgaagac ctacatgttc gaaatgggcc agtcctgggt gatgggcacc
    10381 aaggacccgg aaaaaacgtg gaacgactat cagcagcaac tgaagaaccg cggtttctat
    10441 caggtcatga tcgttatgca gaaggcctat gaccggcagt acggcggggc agcgaagcca
    10501 gcccaggtcg gagccaagta acgcacgcat cgcgcagaag aaaaccgtcc gccctgccct
    10561 gacgtggggg cggatggatc gaaacggatg cgcgccagcg atggcgcagc atccgacctt
    10621 tggcgccgca tctcgctgcg gcgtccaact cggaggagca aagcaccatg aagaagatga
    10681 tgttgtccgt cgcagcagtg gccacgctga tggcctttgc cgcgcccgtc gccacggcga
    10741 aggaggccac ctgggtgacc gacaagccct tgacgctgaa gatccatatg cacttccgcg
    10801 acaagtgggt gtgggacgag aactggccgg tcgccaagga atcgttccgc ctgaccaacg
    10861 tgaagctgca aagcgtcgcc aacaaggccg ccacgaacag ccaggaacag ttcaacctga
    10921 tgatggcttc gggcgacctg ccggacgtcg ttggcggtga caacctgaag gacaagttca
    10981 ttcagtacgg gcaggaaggc gcattcgttc cgctcaacaa gctgatcgac caatacgccc
    11041 cgcatatcaa ggcgttcttc aaatcgcacc cggaagtcga gcgcgccatc aaggcgccgg
    11101 acggcaacat ctacttcatt ccttacgtgc cggacggcgt ggtcgcgcgc ggctacttca
    11161 tccgcgaaga ctggctcaag aagctcaacc tgaagccgcc tcagaacatc gatgaactct
    11221 acaccgtgct caaggcgttc aaggaaaaag acccgaacgg caacggcaag gccgatgaag
    11281 tgcccttcat cgaccgccat ccggacgaag tcttccgcct ggtgaacttc tggggcgcgc
    11341 gttcgtcggg gtccgataac tacatggact tctacatcga caacggccgc gtcaagcacc
    11401 cgtgggccga aaccgccttc cgcgacggca tgaagcatgt ggcccagtgg tacaaggaag
    11461 gcctgatcga caaggaaatc ttcacccgca aggcacgcgc acgcgaacaa atgttcggtg
    11521 gcaatctggg cggcttcacg cacgactggt tcgccagcac gatgaccttc aacgaaggtc
    11581 tggccaagac ggtgccgggc ttcaagctga ttccgatcgc cccgccgacc aacagcaagg
    11641 gccagcgctg ggaagaagac tcccgccaga aggttcgtcc cgatggctgg gccatcacgg
    11701 tgaagaacaa gaacccggtg gaaaccatca agttctttga cttctacttc agccgtccgg
    11761 gccgcgacat ctccaacttt ggcgttccgg gtgtcacgta tgacatcaag aacggcaagg
    11821 cggtgttcaa ggattccgtg ctcaagtcgc cgcagccggt caacaaccag ctctatgaca
    11881 tgggcgcaca gatccccatc ggcttctggc aggactacga ctacgaacgt cagtggacca
    11941 cgcctgaagc gcaggccggc atcgacatgt acgtcaaggg caagtacgtc atgcctggct
    12001 ttgaaggcgt gaacatgacg cgtgaagagc gcgccatcta cgacaagtac tgggccgacg
    12061 ttcgcacgta catgtatgaa atgggccaag cctgggtgat gggcaccaag gacgtggaca
    12121 agacctggga cgagtaccag cgtcagctca agctgcgcgg tctctaccaa gtgctgcaga
    12181 tgatgcagca agcctacgac cgtcaataca agaactaatc gcatgaccca tgtcccggcc
    12241 gggcggtcgg gacatggcgg cgggcgcccc cgctcgccgc ctgcgcactg gctgcccgcc
    12301 gctgtgcgca ttgaatcgac gtcgacgcgt tttatccgga caccggtgac ggccgcgcgc
    12361 atcgcgcgga agagaaggcc ctgtcgccac aggggcagtc atcgctggag cagcacgcgc
    12421 accgacgcaa cacgacaacg aaggacagag tgatgaagaa gctggaacag ccgcagtccg
    12481 cggacatgac aatcagatat ttccccgaca gtgacacgct gaccgaaaat ccgccgcgct
    12541 ttctgtggct gccggaactc gacagccagg cgcgctacgc cgtgcgcgtg gtgtcggacg
    12601 cggggaaaga gacggtgttc ggcgacatcc agcacaactt cttccgcccc gacgtcacac
    12661 tgacgccggg tagctacacc tggtcttacg ctctgtggga cgcagccgca ggcaaggtcg
    12721 actccgactg gagctccccg cgcagcttcg ttctgcccgc cgacgcgccc gctgtgcccg
    12781 gcatgcgcca taaagaacgg tacgccgagt gcgacatgac gcacccgcgc ctgtggctgt
    12841 cgcaaagcga agccaccgcg ttgggcaaga gcgtcgccac cgacccggat cactgcaagt
    12901 gggccaactt catggccaag tcggtcacgc catggatgtc gcgcgagatc atcgccgagc
    12961 cgcagcccta ccccaacaac aagcgcacgc cggccctgtg gcgcaagatg tacatcgact
    13021 gccaggaagt gatctacgcg atccgccacc tggccatcgc cggtcgtgtg ctgggtgatg
    13081 cggccatgac cgcccgcgcc aaggaatggc tgctcgccgt cgccgcgtgg gacgtgcgtg
    13141 gcccgacctg ccgcgactac aacgacgaag ccgccttccg catcgcggca gcactggcct
    13201 ggggctacga ctggctgcac gacgaactgt cggacatcga acgcgccaac gtgcgcgaat
    13261 cgctgacggt gcgcacgcgc gaagtcgcca accacgtgat caaccgcgcc aagattcata
    13321 tcttcccgta cgacagccac gccgtgcgtt cgatttcgtc ggtgctggtg ccctgctcca
    13381 tcgtgctgct gggcgaagtg cccgaagccc agaagtggct cgactactcc atcgatttct
    13441 acgacgcgat ctacccaccg tggggcggcg tggacggcgg ctgggccgag ggtccgcact
    13501 actggatgac ggccatggcc tacttcaccg aggcggccaa cctcgtgttg aagtacttca
    13561 agcatgacct gtacaagcgc ccgttcttcc agagcactgg ctggttcccg ctctacacca
    13621 aggccccgga cacgcgtcgt gcgtgctttg gcgatgactc cacgctcggc gacctgccct
    13681 gcctgaaggt gggctacaac ctgcgccaat tcgccggcgt caccggcaac ccgtacttcc
    13741 agtggtactt cgaagaggtg tgccgcaacg atccgggcac cgaaatggag ttctacaact
    13801 acggttggtg ggacctgaac ttcgacgacg tgcagtacct gcacgacttc ccgcacatcg
    13861 aagcgaaggc gccgtccgac atcgacaccg tcaagtactt tggcgatgtt ggctgggtcg
    13921 cgctgcaacg gcacatggac aagccggatc agcacatcca gttcctcacc aaggccagcg
    13981 acttcggctc gatcagtcac agccatggag accagggtgc gttcctgctg tatggctacg
    14041 gcgaagacct ggccatccag agcggctact acatcggttt cggcaccacc atgcacaagg
    14101 aatggcgccg actgaccaaa tcgaagaacg ccattctcat cgacgggaag gggcaatatt
    14161 caggttcgaa caaagccgaa tgcctcaagg cgcaaggtca tgtgctggaa gtaggcacgc
    14221 gtaacggcgc gcacttcatc agcctcgacc cgaccgacgc gtacaaggcc gaggtgccct
    14281 acctcacccg ctatcgtcgc gacattcact tcgtgcatga ccgcttcttc gtcatcgtcg
    14341 acgacgtcga actggaacag gacggcagcg tgcagtggct catgcacacc ttcaagccgt
    14401 gcgaactcgg ctcgcaggtg ttccgctacc acggtgacaa agcgggcctg aatggcgaat
    14461 tcgtctattg ctcgtccggc ccggtgagca tcgagaacac ggtctcgtac gccaatatcg
    14521 atcagagcga agttgaagga ctgccaccgc aatccacgct ggtggcgagc accggcgccg
    14581 cacgtcgcca cacattggtg accttgctca caccgtacgc actgtcggcg ccgctgcgcg
    14641 tattccactt caacgacgat cagggcttct cgaccaacct gtacttccag gacggcaaca
    14701 acgagatgta caccatcacg ttgcccaaac cgttctaagc aggaacctgt ccgcgacagg
    14761 tagcgagcgg ttaccagcgg agccaagcgc cccgatgaca acctctcagc gccagcgagc
    14821 aggtccggca gtgcagcgaa cagcgtaaat gg
//
