LOCUS       NC_010999              11193 bp    DNA     linear   CON 17-FEB-2020
DEFINITION  Lactobacillus casei BL23, complete sequence.
ACCESSION   NC_010999
VERSION     NC_010999.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMEA2272724
            Assembly: GCF_000026485.1
KEYWORDS    RefSeq; complete genome.
SOURCE      Lactobacillus casei BL23
  ORGANISM  Lactobacillus casei BL23
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
            Lactobacillus.
REFERENCE   1
  AUTHORS   Maze,A., Boel,G., Zuniga,M., Bourand,A., Loux,V., Yebra,M.J.,
            Monedero,V., Correia,K., Jacques,N., Beaufils,S., Poncet,S.,
            Joyet,P., Milohanic,E., Casaregola,S., Auffray,Y.,
            Perez-Martinez,G., Gibrat,J.F., Zagorec,M., Francke,C., Hartke,A.
            and Deutscher,J.
  TITLE     Complete genome sequence of the probiotic Lactobacillus casei strain
            BL23
  JOURNAL   J. Bacteriol. 192 (10), 2647-2648 (2010)
   PUBMED   20348264
REFERENCE   2  (bases 1 to 11193)
  AUTHORS   Loux,V.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-JUN-2008) Loux V., Unite MIG, I.N.R.A, Domaine de
            Vilvert, 78352 Jouy en Josas Cedex, FRANCE
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/17/2020 14:41:02
            Annotation Pipeline               :: NCBI Prokaryotic Genome
            Annotation Method                 :: Best-placed reference protein
            Annotation Software revision      :: 4.11
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
            Genes (total)                     :: 3,020
            CDSs (total)                      :: 2,941
            Genes (coding)                    :: 2,878
            CDSs (with protein)               :: 2,878
            Genes (RNA)                       :: 79
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 30 of 63
            Pseudo Genes (incomplete)         :: 24 of 63
            Pseudo Genes (internal stop)      :: 13 of 63
            Pseudo Genes (multiple problems)  :: 4 of 63
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence was derived from
            FM177140.
            Source DNA and bacteria available from Josef Deutscher
            (josef.deutscher@grignon.inra.fr) or Manuel Zuniga
            (btcman@iata.csic.es) Finishing done by Lactobacillus casei BL23
            sequencing consortium Automatic Annotation done by INRA-MIG with
            Agmial
            URL http://genome.jouy.inra.fr/agmial.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotation Pipeline (PGAP)
            set; GeneMarkS-2+
            repeat_region
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..11193
                     /organism="Lactobacillus casei BL23"
                     /mol_type="genomic DNA"
                     /strain="BL23"
                     /db_xref="taxon:543734"
     gene            1..1710
                     /locus_tag="LCABL_RS01420"
                     /old_locus_tag="LCABL_02860"
     CDS             1..1710
                     /locus_tag="LCABL_RS01420"
                     /old_locus_tag="LCABL_02860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003563123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH20"
                     /protein_id="WP_012490882.1"
                     /translation="MKKHGFRFWLLAIVGLLGMVLSLSQPPKQVAAADNTLKSVFSIDA
                     GRKFFSADQLKMIIDRAHTDGYTDVQVLLGNDALRLLLDDMSVTINGKTYGSDVVKQAI
                     QAGNKAYYDDPNGNALTQTDMDAVLKYAAARDINIIPVINSPGHMDAILTAMAQLGIKN
                     PAFNGSKRTVDLNNDTAIAFTKALLQKYVMYFKGHATIFNFGSDEYANDVDTGGWAKLQ
                     QSGTYKKFVAYVNDLAAMAKNASLKPMVFNDGIYYDNNTSFGTFDKDLIVSYWTAGWGG
                     YDVAKPEFLTDKGLKIMNTNDGWYWVLGRVDGDLYSYKTALASLASKKFTDVPGASSAV
                     PIIGSVQAVWADDPSAQLDMPALLKLMDQFSTAYAPYLVRPADYSKVDAAIAAVPRQLN
                     QYTEASVAKLDAALNAVVRGKKATDQALVDGYAQTITVAIKALQLRPADYTKVDAAIAA
                     AKKLDRSHYQDLSAVDAALAAVNRNLSITQQAQADTMAAKITAAIAALVLKPAPQPDPR
                     QQQVPTKTIVNPDRYLPKTAEASGWELMLAGLATIFGVISIVFFWRQHRMAV"
     gene            2091..3110
                     /gene="manA"
                     /locus_tag="LCABL_RS01425"
                     /old_locus_tag="LCABL_02870"
     CDS             2091..3110
                     /gene="manA"
                     /locus_tag="LCABL_RS01425"
                     /old_locus_tag="LCABL_02870"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016388442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="WP_003592893.1"
                     /translation="MRISDLKRLFKKGVGILTEPLFLKPYFNPKIWGGRKLETEYGFDI
                     PDGKIGEAWIISGHPHGPATIENGPLKGKTLREAWHEDPAYFGPQHSQEFPLLVKILDA
                     EASLSVQVHPDDAYAAAHEAKGELGKTECWYILKADPGAYLIYGHHAKTHEQLKEMIEA
                     GDWEHLLRKYPVKTGDFVYVPSGTIHALNKGIVALETQQSSDTTYRLYDYDRKDDQGHK
                     RELHIKQSLDVTTVPFHDPKLDITKEQVTGGQITTFVKPPLSPHFAVYRLDVDGTMTFT
                     QQAPYTNVTVLDGDGTFSADGKDYPIKTGDSFLIPNQIKTWAFTGKLAIVTSTPGVDA"
     gene            3472..4188
                     /locus_tag="LCABL_RS01430"
                     /old_locus_tag="LCABL_02880"
     CDS             3472..4188
                     /locus_tag="LCABL_RS01430"
                     /old_locus_tag="LCABL_02880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014571081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DBD-Pfam|GntR,DBD-SUPERFAMILY|0043758"
                     /protein_id="WP_012490884.1"
                     /translation="MEKVPLTKQLVDQLETFIKEKLQPNDKLPSERDLSELYQVSRNTV
                     RAALNELFLRGFIYRSTGKGTFVAERFDERTDVSGSYSFTKQMLAMNRKPVTRIQRLEK
                     IAAPAKIAKRMRIEPGTPVYVLDRLRIADTLPMMIERSYLPANTVPGLNQEALSKTPLY
                     DWLEGHYGIHIVSVDEAFFAGLVTPEDAEQLRVAPASACLNIRRTTFADTGEIVEYTLS
                     VARADQFVYHVHHVNH"
     gene            4257..5438
                     /locus_tag="LCABL_RS01435"
                     /old_locus_tag="LCABL_02890"
     CDS             4257..5438
                     /locus_tag="LCABL_RS01435"
                     /old_locus_tag="LCABL_02890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003563130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STP|SIS,STP|SIS"
                     /protein_id="WP_003563130.1"
                     /translation="MFEKTTEELTKLGAQITTAEIKQQPELWQEAFDNYTNAKEKITAF
                     LDQVTAAANGKTVRVIFTGAGSSQYVGDTVTPYLRAHGDRSKFEFESIGSTDIVSAPYD
                     FLEADTPTILVSFARSGNSPESLKTVELAEQVVHNLHQISITCAPEGQLAKKSETEDKT
                     LLLLQPAGSNDKGFAMTGSFSCMTLSALLVFDTASDTDKSKWVKAIAAMGQEVVAREAE
                     VQKVLDLDFDRIVYLGSGSLGGLTRETRLKVLELTAGKYATMFDTSMGFRHGPKSFLDD
                     KTLLFDLVSNNAYTRQYDIDVLEEVKGDGIAKSVMAVGTKQDQNFSGDAFYFENGLKDL
                     PEAYQALPDVMFAQTVALLASIKVGNLPDTPSPTGTVNRVVKGVTLHDYAGKE"
     gene            5497..6657
                     /gene="nagA"
                     /locus_tag="LCABL_RS01440"
                     /old_locus_tag="LCABL_02900"
     CDS             5497..6657
                     /gene="nagA"
                     /locus_tag="LCABL_RS01440"
                     /old_locus_tag="LCABL_02900"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016379175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CE9"
                     /protein_id="WP_003573361.1"
                     /translation="MSYYIHAAKFFLKNVTEIGGYLEVTDDGKFGEYLPETAKPDGDIV
                     EQSGKLIAPGLVDTHIHGLLGHDVMDNDWDGIETMSKNLLKAGVTSWLPTTLTGSFDQL
                     NEVCKTIAAHAGDESGAKIQGIYFEGPYFTTKHKGAQNPKYFKNPSEQEYDAWQTSADG
                     LLKKIAIAPEREGAADFTRYATADGTVVALGHSDATFEQAKACIEAGATVFTHTFNGMS
                     PLSHREPGMVGAAMYLQGVDDELICDGHHVRPEVATTLIRLKGAEHIALITDCMRAGMM
                     PDGDYVLGEFPVYVKDGMARMKDGDSLAGSVLELKDALTNLLAWNAATPEAIIRMASQT
                     PAASCNIDDQCGSILPGRAADYLVLDADLKLEATYLDGKLGYQAEA"
     gene            6757..8553
                     /locus_tag="LCABL_RS01445"
                     /old_locus_tag="LCABL_02910"
     CDS             6757..8553
                     /locus_tag="LCABL_RS01445"
                     /old_locus_tag="LCABL_02910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016365502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|W5L187|9.B.207.2.1"
                     /protein_id="WP_012490885.1"
                     /translation="MTTFSIDHEFMLDGQPFKILSGAIHYFRVHPSDWYHSLYNLKALG
                     FNTVETYVPWNLHEYNEGDFDFSGILDIERFLNTAKDLGLYAIVRPSPYICAEWEFGGF
                     PAWLLTKKMRLRTDDPAYLQAIDRYYTALMPHLVGHQVTHGGNVIMMQVENEYGSYGED
                     KDYLAAVAELMKKHGVDVPLFTSDGPWPATLNAGSMADAGILTTGNFGSRADMNFDRLA
                     AFNQAHGHDWPLMCMEFWDGWFNRWGEPIIRRDPEETAEDLRAVIQRGSVNLYMFHGGT
                     NFGFMNGTSARKDHDLPQVTSYDYDAPLNEQGNPTPKYFTIQKMIHEVLPSQAQTTPLV
                     KPAMRQADNPLTAKVSLFSVLDQLAQPVAAPYPQTQEFLGQYTGYTLYRTNPLISGTDK
                     GTPAKLRVIDARDRVQAFFDGKSLATQYQEAIGDDILLPEVEGRHQLDLLVENMSRVNY
                     GSKIEAITQFKGIRTGVMVDLHFIKDYLQYPLDLNKAPQLDFTGDWQAGTPAFYQYGFD
                     VVKPQDTYLDCRGFGKGVMLVNGVNIGRFWGKGPTLSLYVPAGLLHTGHNEVIVFETEG
                     QYAEAINLVDHPIFKELNTEEE"
     gene            8556..9038
                     /locus_tag="LCABL_RS01450"
                     /old_locus_tag="LCABL_02920"
     CDS             8556..9038
                     /locus_tag="LCABL_RS01450"
                     /old_locus_tag="LCABL_02920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003577506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|B3W754|4.A.6.1.18"
                     /protein_id="WP_003563136.1"
                     /translation="MAIIAARIDGRLVHGQVANLWTTKLGATRIMVVDEAASKSDIDKS
                     GLRMATPDGIRLSVLDVATAANHILNHKYDSQKVFIVAKRPETFLALVNAGVPITDLNV
                     GNMSQTDETRSITKSINVVDADVDTFKELDAKGVHLTAQMVPGDTAADFMSLLKKG"
     gene            9051..9968
                     /locus_tag="LCABL_RS01455"
                     /old_locus_tag="LCABL_02930"
     CDS             9051..9968
                     /locus_tag="LCABL_RS01455"
                     /old_locus_tag="LCABL_02930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003563138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|B3W755|4.A.6.1.18"
                     /protein_id="WP_003573365.1"
                     /translation="MIAWWQIALLTLYAGYQILDELQIYSAMSSPVFAGLISGLVMGDM
                     KAGLLIGASTQLMVLGVGTFGGASKIDANSGTILATAFSVSAGMKPEAAVAAIAVPVAS
                     IMIQTDILARFSNTFFAHRIDKMVDQNNYKGIERYFLAGALPWALSRMIPVGLALAFGG
                     GFVTDLAHVLNTSWKWLGDGLATAGAVLPAVGFAILLHYLPLKKHFPYLIMGFVFTVLF
                     TTLFGSVQTLGTAVAGVAKGFTASFNGLSMLAMALIAFAFAAISYQQTTKLHDIAVGNG
                     NTDAASGTAANKTNEQGEITDDEL"
     gene            9955..10776
                     /locus_tag="LCABL_RS01460"
                     /old_locus_tag="LCABL_02940"
     CDS             9955..10776
                     /locus_tag="LCABL_RS01460"
                     /old_locus_tag="LCABL_02940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016387133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|B3W756|4.A.6.1.18"
                     /protein_id="WP_003563140.1"
                     /translation="MMNSNKPTYKLTDKDFRQINRRSLFGFQLGWNYERMQGSGYLYTI
                     LPQLRKIYGDGTPELKKVMKTHTQFFNTSNFFNTIITGIDLAVEEKEGIAGEETVAGIK
                     TGLMGSFAAIGDSIFAALIPAIFGAIAAQMATQGNPVGVFIWIAAQIAVMVFRWKQLRI
                     AYNEGVSLVTTMAHRLAALTDAATLMGVFMVGALVATMINVKIGFAPKIGSVPLDFQKY
                     FDLIIPKLLPALIVGAVYWLLGRKHMTSTRAIFIVLIVSVLLSALGVIAKG"
     gene            10813..11193
                     /locus_tag="LCABL_RS01465"
                     /old_locus_tag="LCABL_02950"
     CDS             10813..11193
                     /locus_tag="LCABL_RS01465"
                     /old_locus_tag="LCABL_02950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016386751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|B3W757|4.A.6.1.18"
                     /protein_id="WP_003563142.1"
                     /translation="MSKLVLISHGQLCEELKKSAEMIMGPQDDIATVALLPNEGPEDFQ
                     AKFKAAVEGQDDVVVLADLKGGTPNNVAARVLAEGGKFDLYSGMNLPMVISFLNAQMLD
                     MKPDLIGDGKAGIAYINDIVKH"
ORIGIN
        1 ttgaagaagc acgggtttcg attttggtta ttggcgattg ttggactgct gggtatggtg
       61 ttgagtctga gtcagccgcc caagcaggta gctgctgctg ataacacctt gaaaagcgtt
      121 ttttcgattg atgcgggacg aaagtttttt tccgcggatc agttgaaaat gatcattgat
      181 cgggcacata cagacggtta caccgatgtg caggttttat tgggcaacga tgcattgcga
      241 ttgctacttg atgacatgag cgtgacgatc aatggcaaaa catatggcag tgatgtcgtg
      301 aaacaggcca tacaggctgg taacaaagcg tactacgatg atccaaacgg gaatgcgttg
      361 acgcaaaccg acatggatgc ggtcttgaaa tatgcagcgg cacgggatat caatatcatt
      421 ccggttatca atagtcccgg ccatatggat gccattttga cggcgatggc gcaactaggc
      481 attaagaatc ctgcctttaa tgggtctaaa cggactgtcg atcttaacaa tgacactgct
      541 attgccttta caaaagcgct attgcagaag tatgtgatgt atttcaaggg gcatgctacg
      601 atcttcaact ttggcagtga cgagtatgca aatgatgtcg atactggcgg ctgggccaag
      661 ttgcaacaaa gtggcaccta caaaaagttt gtggcatacg tcaacgactt agcggcgatg
      721 gccaaaaatg ccagcctgaa gccgatggtt ttcaatgacg ggatttatta tgacaataac
      781 accagtttcg ggacttttga caaggatttg atcgtctctt attggaccgc tggctggggc
      841 gggtatgatg tcgcaaagcc agaatttttg accgataagg gtttgaaaat catgaatacc
      901 aatgacggtt ggtattgggt tttaggtcgc gtggacggcg atctctatag ttacaaaacg
      961 gcgctagcta gtttagcaag taaaaaattt actgatgtac ccggcgcttc gagtgccgtg
     1021 ccgattattg gcagtgtgca ggcggtttgg gcggatgatc cgagtgcaca gttagacatg
     1081 ccggcgctgt tgaagttgat ggatcaattt tcgacagcct atgcacctta cttagttcgc
     1141 ccagccgatt acagtaaagt tgatgccgcc atcgctgccg tgccgcggca acttaatcag
     1201 tacaccgaag catcagttgc taaacttgat gcagcgttaa atgctgttgt ccgcggtaaa
     1261 aaggcaaccg atcaggcatt ggttgacggc tatgcccaga ccattactgt cgccatcaag
     1321 gcactgcaac tgcggccggc cgattacaca aaggttgatg ccgccattgc agctgcaaag
     1381 aaacttgacc ggtcacacta tcaagacctt agtgccgttg atgcggcgct tgctgctgtt
     1441 aatcgtaatc tcagcatcac ccagcaagcc caagctgata ccatggctgc caagattaca
     1501 gctgccatcg ctgcgttggt tctgaagccg gcgccgcaac ccgatccaag gcagcagcaa
     1561 gtgccaacaa aaaccattgt gaatccagac cggtatttac caaaaacggc agaagcttcc
     1621 gggtgggaat tgatgctagc tgggcttgcc acgatttttg gtgtcattag cattgttttc
     1681 ttttggcggc aacatcgcat ggccgtctaa ttcctgacaa taatcaaaaa tacggcccgc
     1741 tacgcatctt ttgcgcaacg ggccgttatg gtgttgtgcg ccaacaccat ttcatagtgt
     1801 cacgcaagga tttgatgaaa ttgtgatgtc attgagatga ttttggctgt tttgacaact
     1861 acctcgccag catttacccg caaaataatc ggctagtaag gttccgtctt gttatttagt
     1921 ttaattgagc cgcaagttta caaaataaag gtcagcggtc tagataggta ctgtataatg
     1981 aacttgaaaa cgacgaaaaa gcagcgcaaa ggcaaattgg ttagaaaacg gcgtattagc
     2041 ggacatgaat gagatgatgg ggtgttcatc atggggttca gaggtttaac atgcggattt
     2101 ctgatctgaa gcgcttgttt aaaaaaggag tgggcatttt gacagaacca ttatttttaa
     2161 aaccatactt taatcctaag atatggggcg gccgcaaact cgaaactgag tacggctttg
     2221 acattccaga cggtaaaatc ggtgaggctt ggatcatctc aggtcatccg catggtccgg
     2281 cgaccattga aaacggtcca ttgaagggta aaacccttcg cgaggcgtgg catgaagatc
     2341 ccgcttattt tggtccacaa catagtcagg agttcccatt gctcgtgaag attctcgatg
     2401 ctgaagctag tttaagtgtt caggttcacc ctgacgatgc ttatgctgcg gcccacgaag
     2461 caaaaggcga actcggtaag actgaatgct ggtacatcct gaaggcagat ccaggggctt
     2521 atttgatcta tgggcatcac gccaaaacgc atgaacagct caaagaaatg atcgaagccg
     2581 gcgattggga gcacttgttg cggaaatatc cagtcaagac tggcgacttt gtgtatgttc
     2641 caagcggcac gatacatgct ttaaacaaag gcatcgtggc attggaaacc caacaaagtt
     2701 ccgatacgac ttatcggctt tacgactatg atcggaaaga tgatcaaggt cacaagcgtg
     2761 agttgcatat taagcaaagc cttgatgtga cgaccgttcc tttccatgac ccgaagctcg
     2821 atatcaccaa agaacaagtg acaggcgggc aaatcaccac gtttgttaaa ccgccgctgt
     2881 caccgcattt tgccgtttat cgccttgatg ttgatggcac catgacgttc acccaacaag
     2941 caccttatac caatgtaaca gtgcttgacg gtgacgggac cttttctgca gacgggaagg
     3001 attacccgat caaaacaggc gatagtttct tgattcccaa ccagatcaag acttgggcat
     3061 tcactggcaa attggcaatc gtcacttcta ctccaggggt agacgcataa ggttgcggat
     3121 catcaggtgc ccaacatatt cataaagaca aaagttatcc ctcgacaggt ttttagacca
     3181 tcgagggatt tttttgttac tggtgtgatt aaatggctgt taaacaaaaa attagaacgt
     3241 aatgagaacg ctttcctatc gaaataatta ttttcctgat ttggtctaat tatggaaatg
     3301 tctgttaccg ctgaattcat gatttcaatt tcttttttta acgaaaattg gtacatgttg
     3361 tcattttgag aacctgtaag tcgttaaaaa taaaaataag tcgcatgtat tgacttcacg
     3421 aactgggaac gcatacacta caagtggttg gtaccacgtg gaggtgagat gatggaaaag
     3481 gttccgttga cgaaacagct ggtagatcag ctggaaacgt tcattaagga gaaacttcag
     3541 cccaacgata agctgccgtc cgagcgggat ctcagcgagt tgtatcaggt cagtcgcaac
     3601 acagttcgtg ctgccttgaa cgaattgttc ttgcgcggtt tcatttatcg aagcactggt
     3661 aaaggtacat ttgttgcaga acgatttgat gagcgaaccg atgtcagtgg gtcctacagt
     3721 ttcactaaac agatgttggc aatgaaccgt aaaccagtga ctagaatcca gcgtttagaa
     3781 aaaattgcgg cacccgccaa aattgccaag cgcatgcgca tcgaaccagg cacgcccgtt
     3841 tacgtccttg atcgattacg aatcgctgac acgttaccga tgatgattga gcgcagttac
     3901 ttacctgcta acactgtgcc aggtcttaat caggaagcac tatcaaaaac gccattatac
     3961 gattggctgg aaggtcatta tggcattcac attgtttcag tcgatgaagc gttttttgct
     4021 ggattagtca cgccggaaga tgctgaacaa cttcgagttg caccagcgtc agcctgtttg
     4081 aacattcggc gaacaacttt tgccgatacc ggcgagattg ttgaatacac cttgagtgtg
     4141 gctcgcgcgg atcaatttgt ttatcacgta catcacgtta atcactagat aataaagcat
     4201 aaaccagtcc ggcttagggg ctggcaagca ggtttccaat aggaggatga agaacattgt
     4261 tcgaaaaaac aactgaagaa ctaaccaagt taggtgcaca aattacaact gctgaaatca
     4321 aacagcagcc agaactatgg caagaagcat ttgataacta taccaacgcc aaggaaaaga
     4381 tcacggcctt tttggatcag gtgacggccg cagctaatgg caaaaccgtt cgcgttattt
     4441 tcactggtgc cggtagttca caatatgttg gtgacacggt gacgccatac ctacgcgcgc
     4501 atggtgatcg cagcaagttc gaatttgaat caattgggtc aactgatatt gtgtccgcac
     4561 cttacgattt tctggaagca gacacgccga ccattctggt ttcctttgct cgtagcggca
     4621 actcaccgga aagtttgaaa actgttgaac tggctgaaca agttgttcac aacctccatc
     4681 aaatcagcat tacctgcgca ccggaaggcc aattggccaa gaagtctgaa acggaagaca
     4741 agactttgtt gctgttacag ccagctggtt caaatgataa aggctttgcc atgacaggca
     4801 gtttctcttg catgaccttg agtgccttgc tggtatttga taccgccagt gacacggata
     4861 agagcaagtg ggtgaaagcc attgcggcaa tgggacaaga agttgtggcg cgtgaagccg
     4921 aagttcaaaa agtgcttgac cttgattttg atcgtatcgt ctatcttggc tctggcagtc
     4981 ttggcggctt gacccgcgaa actcgcctga aggtgcttga actaacggct ggcaagtatg
     5041 ccaccatgtt tgacacttcc atgggcttcc gtcatggtcc aaagagtttc ctagatgaca
     5101 agactttgtt gttcgacctc gttagcaaca atgcctacac ccgtcaatat gatatcgatg
     5161 tccttgagga agttaagggt gacggtattg ctaaatccgt gatggcagtg ggcaccaagc
     5221 aagatcagaa cttctcaggc gatgccttct attttgaaaa tggccttaaa gatcttccag
     5281 aagcttatca ggctctccca gatgtcatgt tcgcccagac tgtagcattg cttgcttcga
     5341 tcaaagttgg caacttgcct gacacaccat caccaaccgg caccgttaac cgagttgtta
     5401 aaggcgtgac cttgcacgat tacgctggta aggaatagag cgtgaactgg caccaagcag
     5461 catcaacgag caagtttaga ggaggcaaaa gagttcatga gttactacat tcacgctgca
     5521 aagttttttc tcaagaatgt gactgaaatt ggtggttatc tagaagtcac cgatgatggc
     5581 aagtttggcg agtatctgcc ggaaacagct aagccagatg gcgatattgt tgaacaatcc
     5641 ggcaaattga ttgctccagg tttagtcgat acccatattc acgggttgtt agggcatgac
     5701 gtaatggaca acgattggga tggcattgag acaatgagca aaaacttgct caaagctggt
     5761 gtcaccagtt ggctgccaac cacattgacc ggttcatttg atcaactcaa tgaggtttgc
     5821 aaaacgattg ccgcacatgc tggcgatgaa agcggtgcga agattcaagg catttatttt
     5881 gaaggcccat actttacgac caagcataaa ggggcacaga atccgaagta cttcaaaaat
     5941 ccaagtgagc aagaatacga tgcttggcag acatccgctg atggcttgtt gaagaaaatt
     6001 gcgattgccc cagaacgtga gggtgctgct gacttcactc ggtatgccac cgcagacggc
     6061 acggtggtgg ctttgggcca tagtgatgcc acctttgagc aggctaaagc ttgtatcgaa
     6121 gccggtgcaa ctgtcttcac acacactttc aatggtatga gcccgttgag ccatcgcgaa
     6181 cctggtatgg tcggagcagc gatgtatctg caaggggttg atgatgagct tatctgtgat
     6241 ggtcatcatg tccgtcctga agtggccacc accttgattc gactgaaagg cgctgaacat
     6301 atcgcattga ttaccgattg catgcgtgcg gggatgatgc ctgatggcga ttacgtcctt
     6361 ggcgaattcc cagtttatgt caaagacggg atggcgcgga tgaaagatgg cgacagtctg
     6421 gcgggttcag ttcttgaatt gaaagatgcg ctgaccaatc tccttgcttg gaacgccgca
     6481 acaccagaag caattattcg aatggcttct caaacaccgg ctgcttcttg caatatcgac
     6541 gatcaatgcg gcagtatttt acctggccga gccgctgatt atctagtttt ggacgctgat
     6601 ctcaagctcg aagccaccta tcttgatggc aaattaggct atcaagctga agcatgaaag
     6661 ctttcctgac acaaaacctt gtgaaataag gtgtcagtgt gtgacactta aatatggcag
     6721 cataagctgt tatgaatgaa aggaggccag cgctgcatga cgaccttttc gatcgatcat
     6781 gagtttatgt tggacggtca gccgttcaag attctgtctg gcgcgattca ttacttccga
     6841 gtccatccca gtgattggta tcacagcctt tataacttga aggcactggg atttaacacg
     6901 gtagaaacct atgtcccttg gaatctgcac gagtacaacg aaggtgactt tgatttcagc
     6961 gggattctcg acattgaacg ctttctaaac accgcaaagg atcttggctt atatgccatc
     7021 gtgcgaccat ccccttacat ctgcgcagaa tgggagttcg gcgggtttcc agcatggctg
     7081 ttaacgaaaa agatgcgctt gcgaaccgac gatcctgcct atctgcaagc gattgaccga
     7141 tactacacag ctttaatgcc tcatcttgtg ggtcatcaag tcacgcatgg tggcaatgtc
     7201 atcatgatgc aagtggaaaa tgagtacggt tcatatggcg aagacaagga ctatcttgcc
     7261 gccgtggccg aacttatgaa aaagcatggc gttgatgtcc cgctttttac ctcggatggt
     7321 ccctggccag caaccttgaa cgctggcagc atggccgacg ctggtatttt gactaccggc
     7381 aattttggct cacgtgccga catgaatttc gatcggttgg cggccttcaa tcaagctcat
     7441 ggacatgatt ggccgttgat gtgtatggaa ttctgggacg gctggttcaa ccgctggggc
     7501 gaaccgatca ttcgccgcga cccagaagaa actgccgagg acttgcgagc ggtgatccaa
     7561 cgcggcagtg tcaatctcta catgttccac gggggaacta attttggctt tatgaacggt
     7621 acctcagctc gcaaagatca tgatctaccg caagtgactt cctacgatta cgatgcacca
     7681 ttgaatgagc aaggcaatcc aacgccaaag tactttacca ttcagaaaat gatccacgaa
     7741 gtcttgccat cgcaggccca gaccacaccg ctggtcaagc cagcgatgag gcaagcggac
     7801 aatccgttga cggcgaaagt gtcattattc tcagtacttg atcagctagc tcagccagta
     7861 gccgcacctt atccgcagac acaggagttt cttggccaat acaccggtta tacgttgtat
     7921 cgaacaaacc cgctgatcag tggtaccgac aaaggcacgc cggctaagtt gcgcgtgatt
     7981 gatgcccgtg atcgggttca agccttcttt gatggcaagt cgctagcaac acagtatcaa
     8041 gaggccatcg gcgatgacat cctgctccca gaagttgaag gccgccatca actagatctg
     8101 ttggtcgaaa acatgagccg cgtcaactat ggctcaaaaa tcgaagcgat tacccagttt
     8161 aagggaattc gcaccggtgt catggtagac ctccatttca ttaaggacta cctgcaatac
     8221 ccacttgact tgaacaaggc gccgcaactt gatttcaccg gcgattggca agcagggaca
     8281 cccgcttttt atcaatatgg gtttgatgtg gtgaaaccac aagatacgta tcttgattgt
     8341 cgtggatttg gtaaaggagt gatgctggtc aatggtgtta acatcggcag attctggggg
     8401 aaggggccaa cgttgtcact atatgtgcca gccgggttgc ttcacaccgg gcacaatgag
     8461 gtcattgttt ttgaaaccga aggccaatat gccgaggcga taaacttggt tgaccaccca
     8521 atatttaagg aactgaacac agaggaggaa taaaaatggc tattattgca gcacgtattg
     8581 atggtcgctt ggtccatggc caagttgcca atctctggac tactaagctc ggcgcaacgc
     8641 ggattatggt cgtggacgag gccgcatcaa agagtgatat cgacaagagc ggattacgga
     8701 tggcaacccc agatggtatt cgcctgtctg ttctcgatgt tgccacagca gcaaaccaca
     8761 ttttgaatca caaatatgat tcacaaaagg ttttcattgt ggcaaagcgg ccggagacat
     8821 tcctcgcatt ggtgaatgca ggtgttccga tcaccgactt gaacgttggt aatatgtctc
     8881 aaactgatga aacccgttca atcacgaagt ccatcaacgt ggtggacgct gacgttgaca
     8941 catttaaaga acttgatgca aaaggggttc atctcacagc gcaaatggtt ccaggcgaca
     9001 cagcagcgga cttcatgtcc ctgctcaaaa aaggataggg ggagtcaaac atgattgcat
     9061 ggtggcaaat agcactttta acattatatg caggctatca aattcttgat gaactgcaaa
     9121 tttattcagc catgagttca ccagttttcg ccggcttaat ttccggcttg gttatgggcg
     9181 atatgaaagc cggtctgttg atcggtgcat ccacacagtt gatggttctt ggggtcggca
     9241 cattcggtgg tgcatctaaa attgatgcca actctggtac cattctcgca acggcattct
     9301 ccgttagcgc cggcatgaag ccagaagcag cggttgctgc gattgcggtt cctgttgcaa
     9361 gtatcatgat tcaaactgat attcttgctc gattctcgaa cactttcttt gctcatcgga
     9421 ttgacaagat ggttgatcaa aataactaca aaggtatcga acgttacttc ctcgctggcg
     9481 cgcttccgtg ggcactgtca cggatgattc cagttggctt ggctttagca tttggcggcg
     9541 gcttcgttac cgaccttgcc catgttttga ataccagctg gaaatggtta ggcgatggct
     9601 tggcaacagc tggtgccgtc ttgcctgctg tcgggtttgc cattctgttg cattacctgc
     9661 cacttaagaa acacttccca tacctcatta tgggctttgt tttcaccgtg ctgttcacga
     9721 cactgtttgg cagcgttcag accttgggta ccgcagttgc tggggtagct aaagggttca
     9781 ctgcttcctt caacggtttg tccatgcttg ctatggcatt gattgcgttt gcctttgctg
     9841 caatcagcta tcaacaaaca acaaagctgc acgatatcgc agttggcaat ggtaatacag
     9901 atgcagcatc aggcacagcc gcaaacaaga ctaatgaaca gggggaaatc accgatgatg
     9961 aactctaata aacctacgta caaattgacc gataaagatt tccggcagat taaccggcgc
    10021 agcctgttcg gcttccagtt gggttggaac tacgaacgga tgcaaggttc gggttatctt
    10081 tacaccattt tgccgcaatt gcgcaaaatc tacggtgatg gcacaccaga gctcaagaaa
    10141 gtcatgaaaa cccacaccca gttcttcaac acgtcaaact tcttcaatac catcatcact
    10201 gggattgatt tggcggtcga agaaaaagaa gggattgctg gcgaagaaac tgttgccggg
    10261 attaaaaccg gtttgatggg gtccttcgct gctatcggtg attccatctt tgctgccttg
    10321 attccagcta ttttcggggc gattgctgca caaatggcaa cgcaaggcaa cccagttggg
    10381 gtcttcatct ggatcgctgc tcaaattgcc gtcatggtat ttcgttggaa gcaattgcga
    10441 attgcttata acgaaggggt ttcgttggtc acaacaatgg cgcatcgatt ggctgctttg
    10501 actgacgctg ctaccttgat gggtgtcttc atggttggtg ccttggtcgc aaccatgatc
    10561 aatgttaaga ttggttttgc gccgaagatc ggcagtgtac cattggattt ccagaaatac
    10621 tttgacttga tcattccaaa actgcttcca gccttgattg ttggcgcggt ttactggttg
    10681 cttggtcgta agcatatgac ctcaacccgg gcgattttca tcgtattgat cgtttcggtg
    10741 ctgctgtcgg cactcggtgt cattgctaag ggttaatttg gtatcagaaa cgttttaaag
    10801 gagtctttcg atatgagtaa attagttttg attagtcacg ggcaactgtg tgaggagctt
    10861 aagaagagcg ctgaaatgat catgggtccc caagacgata ttgccaccgt tgcactgttg
    10921 ccaaatgaag gtccggaaga ttttcaggcc aagtttaaag ctgctgtaga ggggcaagac
    10981 gatgttgtcg tccttgccga ccttaaaggc ggaacgccga ataacgtcgc agcccgtgtc
    11041 ttggctgaag gcggcaagtt cgacctgtat tctggcatga acctgccgat ggtcatcagt
    11101 ttcctgaatg cccagatgtt ggacatgaag ccagatctga tcggcgatgg taaggctggc
    11161 attgcttata tcaatgacat tgtgaagcat taa
//
