LOCUS       AAXF02000047           22100 bp    DNA     linear   BCT 04-AUG-2012
DEFINITION  Bacteroides ovatus ATCC 8483 B_ovatus-MSIQ_Cont517, whole genome
            shotgun sequence.
ACCESSION   AAXF02000047
VERSION     AAXF02000047.1
DBLINK      BioProject: PRJNA18191
            BioSample: SAMN00627058
KEYWORDS    WGS.
SOURCE      Bacteroides ovatus ATCC 8483
  ORGANISM  Bacteroides ovatus ATCC 8483
            Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
            Bacteroides.
REFERENCE   1  (bases 1 to 22100)
  AUTHORS   Sudarsanam,P., Ley,R., Guruge,J., Turnbaugh,P.J., Mahowald,M.,
            Liep,D. and Gordon,J.
  TITLE     Draft genome sequence of Bacteroides ovatus (ATCC 8483)
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 22100)
  AUTHORS   Fulton,L., Clifton,S., Fulton,B., Xu,J., Minx,P., Mardis,E.R. and
            Wilson,R.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (15-FEB-2007) Genome Sequencing Center, Washington
            University School of Medicine, 4444 Forest Park, St. Louis, MO
            63108, USA
REFERENCE   3  (bases 1 to 22100)
  AUTHORS   Fulton,L., Clifton,S., Fulton,B., Xu,J., Minx,P., Pepin,K.H.,
            Johnson,M., Thiruvilangam,P., Bhonagiri,V., Nash,W.E., Mardis,E.R.
            and Wilson,R.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-MAR-2007) Genome Sequencing Center, Washington
            University School of Medicine, 4444 Forest Park, St. Louis, MO
            63108, USA
COMMENT     Bacteroides ovatus (GenBank Accession Number for 16S rDNA gene:
            X83952) is a member of the division Bacteroidetes. In one
            comprehensive 16S rDNA sequence-based enumeration of the colonic
            microbiota of three healthy adult humans, it represents, on
            average, 0.034% of all 16S rDNA sequences and 0.071% of the
            sequences in its division (Eckburg et. al. (2005)). The sequenced
            strain was obtained from ATCC (ATCC 8483T).
            We have collected 6.9X coverage in plasmid end reads and 454 reads.
            We will be performing one round of automated sequence improvement
            (pre-finishing).
            Sequencing/Assembly: The genomic DNA was purified from liquid
            culture derived from a single bacterial colony. A hybrid sequencing
            strategy that utilized reads from both 454 GS-20 and ABI 3730xl
            sequencers was devised and implemented to generate the draft genome
            sequences.  454 reads were assembled using Newbler (454 Life
            Sciences) into 454 de novo contigs. These de novo contigs were
            converted in silico to 800 base paired reads ('superreads') with
            400 base overlaps with neighboring superreads.  Finally, PCAP
            (Huang, et al, Genome Research, 13:2164, (2003)) was used to
            assemble the super-reads and the conventional 3730xl capillary
            reads.
            This sequenced strain is part of a comprehensive, sequence-based
            survey of members of the normal human gut microbiota.  A joint
            effort of the WU-GSC and the Center for Genome Sciences at
            Washington University School of Medicine, the purpose of this
            survey is to provide the general scientific community with a broad
            view of the gene content of 100 representatives of the major
            divisions represented in the intestine's microbial community. This
            information should provide a frame of reference for analyzing
            metagenomic studies of the human gut microbiome. Further details of
            this effort are described in a white paper entitled 'Extending Our
            View of Self: the Human Gut Microbiome Initiative (HGMI)'
            (http://www.genome.gov/Pages/Research/Sequencing/SeqProposals/HGMIS
            eq.pdf). These studies are supported by National Human Genome
            Research Institute.
            Coding sequences were predicted using GeneMark v3.3 and Glimmer2
            v2.13. Intergenic regions notspanned by GeneMark and Glimmer2 were
            blasted against NCBI'snon-redundant (NR) database and predictions
            generated based on proteinalignments. RNA genes were determined
            using tRNAscan-SE 1.23 or Rfamv8.0. Gene names are generated at the
            contig level and may notnecessarily reflect any known order or
            orientation betweencontigs.
            For answers to your questions regarding this assembly or project,
            or any other GSC genome project, please visit our Genome Groups web
            page (http://genome.wustl.edu/genome_group_index.cgi) and email the
            designated contact person.
            Annotation was added to the contigs in August 2007, and the CDS
            comments were updated in January 2008.
            This is a reference genome for the Human Microbiome Project. This
            project is co-owned with the Human Microbiome Project DACC.
            Product names were updated in August 2012.
FEATURES             Location/Qualifiers
     source          1..22100
                     /organism="Bacteroides ovatus ATCC 8483"
                     /mol_type="genomic DNA"
                     /strain="ATCC 8483"
                     /type_material="type strain of Bacteroides ovatus"
                     /db_xref="ATCC:8483"
                     /db_xref="taxon:411476"
     gene            1..1896
                     /locus_tag="BACOVA_02085"
     CDS             1..1896
                     /locus_tag="BACOVA_02085"
                     /inference="protein motif:Gene3D:IPR009014"
                     /inference="protein motif:HMMPfam:IPR002880"
                     /inference="protein motif:superfamily:IPR009014"
                     /note="KEGG: bth:BT2836 0. korA; 2-oxoglutarate synthase
                     subunit korA K00174; COG: COG1014 Pyruvate:ferredoxin
                     oxidoreductase and related 2-oxoacid:ferredoxin
                     oxidoreductases, gamma subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase, alpha subunit"
                     /protein_id="EDO12195.1"
                     /db_xref="InterPro:IPR002880"
                     /db_xref="InterPro:IPR009014"
                     /translation="MKVKSVFKLNIVIKVMADEMMVKELEEVVVRFSGDSGDGMQLAGN
                     IFSNVSATVGNDICTFPDYPADIRAPQGSLTGVSGFQVHIGAGQVYTPGDRCHVLVAMN
                     PSALKTQIKFCKPQGLIITDSDSFEARDLEKAQFKTNNPFEELGIKQEVLEVPISSMCK
                     ESLKDSGLDNKSILRCKNMFALGLVCWLFNRNLAAAEKMLREKFAKKPEIAEANIKVLN
                     DGFNYGANTHASVSTYKIESKAPKSKGLYTDINGNKATAYGLIAAAEKAGLGLYLGSYP
                     ITPATDILHELAKHKSLGVKTVQCEDEIAGCASAVGAAFAGALAVTTTSGPGVCLKSEA
                     MNLAVIGELPLVIVNVQRGGPSTGLPTKSEQTDLLQALYGRNGESPMPVIAATSPTNCF
                     DAAYMACKIALEHMTPVVLLTDAFVANGSAAWKLPNLDEYPAINPPYVTPDMAGNWTPY
                     QRNPETGVRYWATPGTEGFMHRIGGLEKSNETGVISTEPENHNKMVHLRQAKVDKIADY
                     IPELEVLGDEDADLLIVGWGGTYGHLRLAMDYMREHGKKVAFAHFQYINPLPKNTADVL
                     RKYKKIVVAEQNLGQFAGYLRMKVPGLNISQFNQVKGQPFVTRELIDAFTKLLEE"
     gene            1900..2910
                     /locus_tag="BACOVA_02086"
     CDS             1900..2910
                     /locus_tag="BACOVA_02086"
                     /inference="protein motif:HMMPfam:IPR011766"
                     /inference="similar to AA sequence:REFSEQ:NP_811749.1"
                     /note="KEGG: bth:BT2837 1.0e-177 korB; 2-oxoglutarate
                     synthase subunit korB K00175; COG: COG1013
                     Pyruvate:ferredoxin oxidoreductase and related
                     2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort
                     location: Cytoplasmic, score:8.96"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate enzyme, C-terminal TPP
                     binding domain protein"
                     /protein_id="EDO12196.1"
                     /db_xref="InterPro:IPR011766"
                     /translation="MSDKVYTVQDYKSGQPRWCPGCGDHAFLNSLHKAMAELGTAPHDI
                     AVISGIGCSSRLPYYVNTYGFHTIHGRAAAIATGAKVANPNLTIWQISGDGDGLAIGGN
                     HFIHALRRNIDLNMILLNNRIYGLTKGQYSPTSERGLVTKSSPYGTVEDPFRPAELAFG
                     ARGRFFARCIAVDGAASVEVLKAAANHKGASVVEVLQNCVIFNDGTHASVATKEGRAKN
                     AIYLEHGKPMLFGENKEFGLMQEGFGLKVVKLGENGITEKDILIHDAHCQDNTLQLKLA
                     LMEGPDFPIALGVIRDVDAPTYNDAVVEQIEEIKGKKKYHNFQELLMTNETWEVK"
     gene            complement(3012..3212)
                     /locus_tag="BACOVA_02087"
     CDS             complement(3012..3212)
                     /locus_tag="BACOVA_02087"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="EDO12197.1"
                     /translation="MYGDNGALLISLQPFSSNPVWNCLFLGVKHFVSLLETFRFSVRNK
                     WFHGMKQITACGVTPSMLWDD"
     gene            complement(3185..4375)
                     /locus_tag="BACOVA_02088"
     CDS             complement(3185..4375)
                     /locus_tag="BACOVA_02088"
                     /EC_number="5.1.3.8"
                     /inference="protein motif:Gene3D:IPR013330"
                     /inference="protein motif:HMMPfam:IPR010819"
                     /inference="protein motif:superfamily:IPR008928"
                     /inference="similar to AA sequence:REFSEQ:YP_098134.1"
                     /note="KEGG: syn:slr1975 5.6e-20 renin-binding protein
                     K01787; COG: COG2942 N-acyl-D-glucosamine 2-epimerase;
                     Psort location: Cytoplasmic, score:8.96"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acylglucosamine 2-epimerase"
                     /protein_id="EDO12198.1"
                     /db_xref="InterPro:IPR008928"
                     /db_xref="InterPro:IPR010819"
                     /db_xref="InterPro:IPR013330"
                     /translation="METTIERLKEEVQQVLTTNILPYWIEKMQDRGNGGFYGRITGQEC
                     LVAEAEKGAVMNARILWTFSAAYRLLHKTEYLEIATRAKREIIDRFYDTQFGGVYWSID
                     AHGQPLDTKKQVYAIGFAIYGLSEYHRATADDEALEYAVRLFHDIELHCFDKGKNGYYE
                     AFSREWGEIADMRLSDKDANERKTMNTHLHILEPYTNLFRIWKDEMLKSRLHNLIRLFI
                     DEIMDMDTRHLQLFFDDNWRSNYHIISYGHDIEASWLIHEAALVLADRQLLTEIEMYIV
                     EMAEAAAEGFLSDGGMIYELRTDSSSIDADRHWWVQAETVVGFMNLYQHFGDKLSLSRA
                     VRCWEFIKKYLIDYANGEWYWSLSADGTVNREDDKAGFWKCPYHNGRMCMEIMERF"
     gene            complement(4388..5761)
                     /locus_tag="BACOVA_02089"
     CDS             complement(4388..5761)
                     /locus_tag="BACOVA_02089"
                     /inference="protein motif:HMMPfam:IPR011701"
                     /inference="protein motif:HMMTigr:IPR001927"
                     /inference="similar to AA sequence:INSD:CAH06519.1"
                     /note="KEGG: eci:UTI89_C4210 2.1e-74 yicJ; hypothetical
                     symporter YicJ K03292; COG: COG2211 Na+/melibiose symporter
                     and related transporters; Psort location:
                     CytoplasmicMembrane, score:10.00"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|A1S5F2|2.A.2.3.6"
                     /protein_id="EDO12199.1"
                     /db_xref="InterPro:IPR001927"
                     /db_xref="InterPro:IPR011701"
                     /translation="MIKLKEKIGYGLGDMASSMFWKLFGSYLMIFYTDVFGMSAAVVGT
                     MFLVTRVWDSAFDPIVGIIADRTHSRWGKFRPYLLFLAFPFAFIGILTFTTPEWSMTAK
                     IVYAYITYSLMMMVYSAINVPYASLLGVMSAEPHDRNVLSVYRMVFAYLGSFIALLLFM
                     PMVNAFSEGHGEQYGWEMAVTVIAVMCTVFFIGCFALTRERVKPIREKQAPLKDDLKDL
                     LHNRPWWILLGAGIAALIFNSIRDGATVYYFKYFIVENSNEPVTFLGIPFVLSGLYLAI
                     GQAANIIGVVLAAPVSNRIGKKRTYMWAMVVATVLSIVFYWFDKENLVLIFIFQILISI
                     CAGSIFPLLWSMYADCVDYSELKTGNRATGLIFSSSSMSQKFGWAIGSAVTGWLLGYFG
                     FQANVVQNDQAINGIRMFLSFLPAIGTLLSILFISMYPLSERRMKEIIGELEQKRNQH"
     gene            complement(5791..7008)
                     /locus_tag="BACOVA_02090"
     CDS             complement(5791..7008)
                     /locus_tag="BACOVA_02090"
                     /inference="protein motif:HMMPfam:IPR007184"
                     /inference="protein motif:HMMPIR:IPR007184"
                     /inference="similar to AA sequence:INSD:CAH06518.1"
                     /note="COG: COG2152 Predicted glycosylase"
                     /codon_start=1
                     /transl_table=11
                     /product="GH130"
                     /protein_id="EDO12200.1"
                     /db_xref="InterPro:IPR007184"
                     /translation="MNIYKRITTFNLTIDMITFKEKLNTLFDDYNKLITSKNVPLEDGN
                     GILTRYKYPILTAAHTPVFWRYDLDSESNPYLMERIGMNATLNSGAIKWNGKYLLVVRV
                     EGADRKSFFAVAESPNGIDNFRFWDYPITMPEDVIPATNIYDMRLTAHEDGWVYGIFCA
                     ERHDPAAPAGDLSSATATAAIARTKDFVNWERLPDLKTGSQQRNVVLHPEFVNGKYALY
                     TRPQDGFIDAGSGGGIGWALVDDMTHAEVREETIIDRRYYHTIKEVKNGEGPHPIKTPK
                     GWLHLAHGVRGCAAGLRYVLYMYMTSLEDPTRVIASPAGAIMVPEGGERVGDVSNVLFS
                     NGWIADEDGKVFIYYASSDTRMHVATSTIDRLVDYCLNTPQDGYSSSASVEILKRQIAK
                     NLKLMS"
     gene            complement(7005..9215)
                     /locus_tag="BACOVA_02091"
     CDS             complement(7005..9215)
                     /locus_tag="BACOVA_02091"
                     /inference="protein motif:FPrintScan:IPR002252"
                     /inference="protein motif:HMMPfam:IPR000111"
                     /inference="similar to AA sequence:INSD:BAD47299.1"
                     /note="KEGG: bfr:BF0550 7.0e-163 alpha-galactosidase
                     K07407; COG: COG3345 Alpha-galactosidase"
                     /codon_start=1
                     /transl_table=11
                     /product="GH36"
                     /protein_id="EDO12201.1"
                     /db_xref="InterPro:IPR000111"
                     /db_xref="InterPro:IPR002252"
                     /translation="MMKNLIRICLFTMLLFVTGDLAAQNIHLSTPRTSLVLSAPAGGEL
                     KYVYYGSKLTENDCREVYNAPTMQHGAYPVYGMNCPGESALAVTHADGNMTLQMEVAGT
                     EIKNTDGAVTAVIKLKDKVYPFSVNVCYKAYSDVDIIETWTEIAHAEKKNVMLRKFDSA
                     FLPVRRGDVWLSSLYGSWANEGRLVQEPLEPGMKVIKNRDGVRNSHTAHAEVMFSLDGK
                     PQENYGNVIGAALCYGGNYKLRIDTDDSEYHQFYAGINEENSVYNLKKGELFITPALAL
                     TYSAEGLSGCSRNFHRWARKYKLAHGNSLRKILLNSWEGVYFDINENGMNQMMGDIASM
                     GGELFVMDDGWFGDKYKRNSDNSSLGDWKVDTGKLPGGIRKLVDDARQYKVKFGIWIEP
                     EMANTTSELYEKHPEWILKAPLREPVLGRGGTQVVLDLGNPQVQDFIFNLVDTLMTNYP
                     EIDYIKWDANMAIMNHGSDYLPKDEQSHLYIAYHRGFENVCRRIRAKYPELTIQACASG
                     GGRANYGVLPYFDEFWVSDNTDALQRIYMQWGASYFFPAIAMASHISAAPNHQTFRTIP
                     LKYRIDVAMSGRLGMEIQPKNMTGEEKELCRKAIADYKMIRPVVQLGDIYRLLSPYDRL
                     GAASLMYVAPEKEKAVFYWWKTEHFCNQHLPRTRMAGLHPDKIYKVTELNRIDNQPLDY
                     EGKAFSGAYLMANGLEMPYNHKVDYHKLSDYSSRVLYLEEVK"
     gene            complement(9222..10322)
                     /locus_tag="BACOVA_02092"
     CDS             complement(9222..10322)
                     /locus_tag="BACOVA_02092"
                     /inference="protein motif:FPrintScan:IPR000805"
                     /inference="protein motif:HMMPfam:IPR000805"
                     /inference="similar to AA sequence:REFSEQ:YP_210469.1"
                     /note="KEGG: bfs:BF0771 1.7e-129 manA; putative mannosidase
                     K01218; COG: COG4124 Beta-mannanase"
                     /codon_start=1
                     /transl_table=11
                     /product="GH26"
                     /protein_id="EDO12202.1"
                     /db_xref="InterPro:IPR000805"
                     /translation="MMKYIILTINAIFCLLLPTACSGSGETGEKTPETVALLQNLKQAE
                     RKGILFGHHDDTAYGIGWEGDKGRSDVKSVCGAYPGVMSFDLGEIELGGTHNLDKVSFA
                     HLREYIIEQYARGGMISLSWHVRNPKTGGDSWDVTDSTVVASVMQGGENHVKMLEWIDR
                     VADFLLSLKTKEGVLIPVVFRPWHEHTGSWFWWGKDLCSSEQYKTLWRMTNDRLRLKGV
                     NNVLLAYSPGMESDTVEEYLERYPGDDIIDVLGTDVYQFERSQYIKQLNKMLTILTEAG
                     KKHDKPIALTETGLEGIPDSLWWTGTLLPVIEKYPLSYVLVWRNAREKSTHYYAPYPGQ
                     VSADDFVKFSRSPKILFVGDNFELYK"
     gene            complement(10340..11422)
                     /locus_tag="BACOVA_02093"
     CDS             complement(10340..11422)
                     /locus_tag="BACOVA_02093"
                     /inference="protein motif:FPrintScan:IPR000805"
                     /inference="protein motif:HMMPfam:IPR000805"
                     /inference="similar to AA sequence:INSD:AAB20175.1"
                     /note="KEGG: sde:Sde_3691 3.3e-46 mannan
                     endo-1,4-beta-mannosidase K01218; COG: COG4124
                     Beta-mannanase"
                     /codon_start=1
                     /transl_table=11
                     /product="GH26"
                     /protein_id="EDO12203.1"
                     /db_xref="InterPro:IPR000805"
                     /translation="MKNIYNFLIYFIFCGIGAGCSSSSGEDFPAPESEPVDNSLIKKEL
                     CTEGASVEAKKVYTYLRNCWGRKTLSSTMANVTWNVNEAIWVNRQTGKYPAIACFDYMN
                     LPASPADWIDYNKISVVEDWWNAGGLVAACWHWNVPVTENSSEYKCMISETDFDITKAL
                     QEGTRENEIIKADLEELAGYLLLLKQKNIPVIWRPLHEAAGKWFWWGKDAASYKRLWKL
                     VYETFKQKGLNNLIWVWTSETNDRDWYPGDAYVDIIGRDVYHKTSAAGLATDFDALKKA
                     FPDKLIALSECGDVATIDKQLAAGAQWAWFMTWYDYEVTKDTTAPVFNSGQHEHADKAW
                     WNNAFGQPGVICRSDLPSFK"
     gene            complement(11442..12575)
                     /locus_tag="BACOVA_02094"
     CDS             complement(11442..12575)
                     /locus_tag="BACOVA_02094"
                     /inference="similar to AA sequence:INSD:BAD47586.1"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="EDO12204.1"
                     /translation="MALSFGACQDIVTYNDNYDDEMASSGAPVIDAVYDSKDRDKLLPI
                     TDGNLEQMIVLDGSNLSRVRKVMFNDVELPVGEVYATASSAYLPIPRQIPLEVNNKLYY
                     ETELGSTTYDFTVSVPLVQVDGLYNEFALPGTSVQLKGKYFDLYGFGGANSTSTVKMNG
                     VELEVDSISDKYMSVVIPEDAQDNSVIEVSYMGAGSVAHTEKIPYRMTDAIIWNLSHPD
                     DYGLWAGKELIINEAGDNEPEILYGPYFRVTGSYGAWNWTNLVCGGFNCPADVAAAPAD
                     YNFKFEVYSPTGHPFYDSAGYGYLIQLNNGNYPWNPSANGSFNTYGKWCTVSIDLQTVS
                     GNAFSEGWTGLSFILQPNSDWNVDHSFANIRIEKKIR"
     gene            complement(12668..14479)
                     /locus_tag="BACOVA_02095"
     CDS             complement(12668..14479)
                     /locus_tag="BACOVA_02095"
                     /inference="protein motif:HMMPfam:IPR012944"
                     /inference="similar to AA sequence:INSD:BAD47585.1"
                     /note="COG: NOG31573 non supervised orthologous group"
                     /codon_start=1
                     /transl_table=11
                     /product="SusD family protein"
                     /protein_id="EDO12205.1"
                     /db_xref="InterPro:IPR012944"
                     /translation="MKLKKIYILLSLSLAGMTTFSACQDFLSEKPYSFVGPEEVGNDDA
                     AVSQWVTGVYSKWADDMFRWGNFPRVLDMDCDYASGPDWAFSNAGAGNYQGDDVTNTIW
                     KGCYNLINRANVAIKYINAITGADERVKTNGLGEVYFQKAFAYFMLVKAYGEIPLFDRA
                     VTDGTGYNNPRRPIADVYAEIVRLLEEEAIPRLYKNTDAEYQTGHVCAGTAVGLLAKVY
                     ATMASGALPAGEKMTVMTGSSYSYNGDDKVLDMPVRREFVKTQVKGYESFDWRDCYEKA
                     AKWAGYLLYPTPDNNYGSHDLLPYDQLWKRSGLGQSTEHLFALQGANGDELYGNSIFEW
                     YNGIDNGRGVVASGLYIGNRYHWYTLFTSQDYRVTQGVKHRFIVSYQDEEGKPKSGFFY
                     PNTPEYVLKATGYDANGNYVAEPEAPYNDGRNYYFNVSNECLAFTNKYADVTDATQKKS
                     DAYWPFLRLADIVLIYAEAKCELDNGVSSEAISALNRVRIRSNATLASSSGDGAIASKQ
                     ALRSAIFEERAKELALEGDRRWDLIRWGIYVEVMNSIGGINKDGSQTHYDEAGVNKHRE
                     QRHLLFPLPSDEVSTNEAIDSNNPGWS"
     gene            complement(14506..17754)
                     /locus_tag="BACOVA_02096"
     CDS             complement(14506..17754)
                     /locus_tag="BACOVA_02096"
                     /inference="protein motif:HMMPfam:IPR000531"
                     /inference="protein motif:HMMPfam:IPR012910"
                     /inference="protein motif:superfamily:IPR008969"
                     /note="COG: NOG26669 non supervised orthologous group"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q45780|1.B.14.6.1"
                     /protein_id="EDO12206.1"
                     /db_xref="InterPro:IPR000531"
                     /db_xref="InterPro:IPR008969"
                     /db_xref="InterPro:IPR012910"
                     /translation="MNLKSRKTVFITGLCLASLVSGVPLPANASADTTAMIQQQSVKIK
                     GRVTDASGEPVIGANVVQKGTTNGTITDLNGDFTLTVSQGAVLQVSFIGYKQQEVSLKN
                     GQAQVTVVLKDDAELLDEVVVVGYGTMKKRDLSGAVSQIKSDDLMKGNPTDLSKGLAGK
                     IAGVQVNQSDGAPGGGISIQIRGTNSFSTNSQPLYIVDGVPFDTGDTPASDTNNSQNKS
                     NPLAFINPHDIQSIDVLKDASATAIYGSRGANGVVIITTKRGEKGNEKVEFSANFTFSK
                     IAKRMDVLDAFTYANYQNEQVLNDYKYSNKPYGKLPYPGAWEYPALPGGGNDTSAGKYL
                     PAPEDFLRPGDYVDEYGNISYVGVADWQDLIYQNGFSQEYNISVSGGSDKGWHSFSGNF
                     LKQDGIIKNSGFTRYSLRSNIGRYITKWLEMGMNTSFTHTDTDFSKTNSSDCGVIRSAL
                     VFPSTYDPQKNKAETGELSWLASNPLAYITNTKDNLRSINVFNSSYMEVKLLSFLKFRQ
                     NLGISYTNNDRGMYYGRETQEGSSTTNINGKAEQSSNWWLGITAESLLTFDKTFGIHSV
                     NAVAGFTAEKSSWGSKAMSATGFPNDITQDFDMSLGANPGKLRSDRGDAALASFLARVN
                     YTLMDKYILTASCRADGSSKFTDKNKWASFLSGAVAWRMSEEKFIKDLGIFSNLKLRLS
                     YGETGNQGIGSYRTLPMLNMANYPFGGAINSGFAEVDWRGPVSDDLRWETTAQYNVGID
                     MGFLNNRINLTVDYYHKKTRDLLQDVKIPSSTGFGSMMVNSGHITNEGLELTGKFYVLQ
                     NTPLKWNIDANISFNRNRIGGLKADQFAQKLWSSADEVFIQRNGCPIGAIYGYVEDGFY
                     DNLAEVMASPSADIRAKGAGMIGEIKYRNFDDNPDITSADRVIIGDTNPDFVYGLTSNF
                     EWKGVTLSFFLQGSQGNDIFNGNLMDMKMGNVGNITHEAYNTRWTEANAAQAKWPKAVS
                     GYERNMLISNRYVEDGSYLKLKSLNIGYVWKPNFKGISNVNVYASATNLFTITGYSWFD
                     PEVNAFGSDASRRGVDVYSYPSSRTFSLGIKVDF"
     gene            18087..22016
                     /locus_tag="BACOVA_02097"
     CDS             18087..22016
                     /locus_tag="BACOVA_02097"
                     /inference="protein motif:BlastProDom:IPR001789"
                     /inference="protein motif:FPrintScan:IPR004358"
                     /inference="protein motif:Gene3D:IPR003594"
                     /inference="protein motif:Gene3D:IPR012287"
                     /inference="protein motif:HMMPfam:IPR000005"
                     /inference="protein motif:HMMPfam:IPR001789"
                     /inference="protein motif:HMMPfam:IPR003594"
                     /inference="protein motif:HMMPfam:IPR003661"
                     /inference="protein motif:HMMPfam:IPR011123"
                     /inference="protein motif:HMMSmart:IPR000005"
                     /inference="protein motif:HMMSmart:IPR001789"
                     /inference="protein motif:HMMSmart:IPR003594"
                     /inference="protein motif:HMMSmart:IPR003661"
                     /inference="protein motif:ScanRegExp:IPR000005"
                     /inference="protein motif:superfamily:IPR003594"
                     /inference="protein motif:superfamily:IPR009057"
                     /inference="protein motif:superfamily:IPR009082"
                     /inference="protein motif:superfamily:IPR011006"
                     /inference="similar to AA sequence:REFSEQ:NP_811772.1"
                     /note="KEGG: ana:all4963 1.6e-47 cyaC; adenylate cyclase
                     carring two-component hybrid sensor and regulator domains;
                     COG: COG0642 Signal transduction histidine kinase; Psort
                     location: CytoplasmicMembrane, score:9.82"
                     /codon_start=1
                     /transl_table=11
                     /product="DBD-Pfam|HTH_AraC,DBD-Pfam|HTH_AraC,DBD-SUPERFAMI
                     LY|0036286,DBD-SUPERFAMILY|0035607"
                     /protein_id="EDO12207.1"
                     /db_xref="InterPro:IPR000005"
                     /db_xref="InterPro:IPR001789"
                     /db_xref="InterPro:IPR003594"
                     /db_xref="InterPro:IPR003661"
                     /db_xref="InterPro:IPR004358"
                     /db_xref="InterPro:IPR009057"
                     /db_xref="InterPro:IPR009082"
                     /db_xref="InterPro:IPR011006"
                     /db_xref="InterPro:IPR011123"
                     /db_xref="InterPro:IPR012287"
                     /translation="MSFHQLGVKTGMSDNYIQAIERDKYGFMWFATRDGLNRYDGYHFK
                     TYTTLRQGAYNNSVEWVAEDAAGNIWIKTPVNYCFYDREMDELDNRTELLLHKIGIFES
                     PRQLFIDDDKNLWCVADNTLYYYIFSDETLYKQSLPGSVNIADMACRNKRCYILMTDGN
                     VINIDWMHKSITKLFHTEIHTTYVPHIYLDFSSQLWVYAPHSADVKCYSLTENNWIDFA
                     ARTELSRERTMITTITDDGKGNIWIGTDGRGIFICPYDKEKGKVTRLFKDVDKLYSLPD
                     NHVTYIYKDNRDVIWIGTGKQGVAYSGLNNLIFENHYCPQLEDVSCFYEDGEGKLWLGF
                     DGEGIASYDKDKNTYTYYKSKNKEIPSDLIVCSFHDNKGRVWWGSFGGGAFYYQNGQFT
                     PLKAAENNPVELPQYIRRITQDNAGNLWFATYSQGLYCLEPSGMLKDYTMSNSTLLTNY
                     IADLAYVDGHSLYVATSSGVYHMNTSTREMTILEQTADGEEVIQDKFANCIYQDSRGLL
                     WIGGRKGVNVYSPKQNKLINLNTANGVSHSYIRAIIEDASHNMWLTTDHGITHVEVVES
                     DATSMPDFRCHPYYEEDGIGNLTFNNFSIFCNHRNEVIAGGGGGYVKIIPRGNDLFYFD
                     RQVIFTDLYIDNECVNANRPAHNGRIILTKNIQLLNNLNLNYSDNSFAVEVSAMDYGNL
                     HKLQYEYRLNKNEEWTKLEGNRIYFNKLAPGTYQLQVRVMKVHDYENDASATLSINVYP
                     PFWLSNIAYSIYALLLVSAISLIFIHMKRKHRRLLLQQKRDMETVQQHEIDEAKLRFFT
                     NVSHDLRTPLSLIITPLEQILATNTAQDIKKELKLIHRNALALLDVINQLLDLRRLDNG
                     KAQLNPSHGDLADFIKEVCDSFYSYGDKKNIAFSLSLKTDNLETDFDKNKMQRIMLNLL
                     SNAFKYNVNHGSVNVVLDRIIKDEREYACIQVADTGIGIREENKAKIFDRFYQEEHSST
                     DYIGSGIGMHIVKEYVTLHNGDIQIRDNHPQGTIFEFMFPIRHECKNINPTATPTERPD
                     IQEEPEQAKTPTGRSLLIVEDNEDFRQFIVDCLKDRFTVYEAEQGEKAMEILALHDISL
                     VISDVRMPIMNGLELCNKIKGDFRYSHIPVILLTARTAQEHMLEGLREGADDYITKPFN
                     LDILLLRIQKLLEWSSRNHQRFGKVEVSPAEITISTIDERLIERAIQAVEENMDNTDFS
                     VEDLSMTVGMSRGHLYKKLMTITGKSPLEFIRVLRIKRGKQLLEQSQESISQIAYQVGL
                     SPKQFAKYFKEEFGCLPSEFNCKKD"
     gene            complement(21990..22100)
                     /locus_tag="BACOVA_02098"
     CDS             complement(21990..22100)
                     /locus_tag="BACOVA_02098"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="EDO12208.1"
                     /translation="MTVTRKGIKFLSPSFIFHCNKSMLSYRESVLFTVEF"
ORIGIN
        1 ttgaaagtaa aatcagtttt taaattaaat atagtaatta aagttatggc agacgaaatg
       61 atggttaaag aattggagga agtagtagta cgtttctccg gcgactccgg cgatggtatg
      121 cagctggccg gcaacatctt ctcgaacgtg tcggctacag tgggaaatga catctgtaca
      181 ttccctgact atccggcaga catccgcgcc ccgcaaggtt cgctaaccgg tgtttccggt
      241 ttccaggtcc acatcggcgc cggacaagtt tacactcccg gagaccgttg ccacgtattg
      301 gtggctatga acccttccgc actgaaaaca caaatcaaat tctgtaaacc gcaaggactt
      361 atcatcaccg actccgactc attcgaagcc agagatttgg aaaaggcaca atttaaaacc
      421 aacaatccct ttgaagaatt aggaataaaa caggaagtat tggaagttcc tatctcttcc
      481 atgtgcaaag agagcctgaa agactccgga ttggataaca aatcgattct ccgttgcaaa
      541 aatatgtttg cactcggatt ggtttgctgg ttgttcaacc gtaaccttgc tgctgctgaa
      601 aaaatgctgc gcgagaaatt cgccaagaaa cccgaaatag cagaagctaa tattaaggta
      661 ttgaacgatg gcttcaacta cggagcaaac actcatgctt ctgtctctac ttataagatt
      721 gaaagcaaag ctccgaaatc aaaaggactt tatacagata tcaacggtaa taaagcaacc
      781 gcttacggac tgattgccgc agctgaaaaa gcaggtctgg ggctctacct gggttcttat
      841 cctatcactc cggctactga tattctgcac gaattagcta aacataaatc attgggagtc
      901 aaaaccgtac agtgcgaaga tgaaatagcc ggttgtgctt ctgcagttgg tgccgctttt
      961 gccggtgctt tggcagtgac tacgacttcc ggccccggtg tttgcctgaa gagtgaggcg
     1021 atgaaccttg ctgtaatcgg tgaacttcca ttggtgattg tcaatgtaca gcgtggcggt
     1081 ccgtctaccg gtcttcctac taaatcagaa cagaccgact tattacaagc cctttacgga
     1141 cgcaacggcg aaagcccgat gcctgtaatc gctgcaacat cgccgaccaa ctgtttcgac
     1201 gccgcttata tggcatgcaa gattgccttg gaacacatga ctccggttgt attgctgact
     1261 gatgctttcg tagctaacgg ttctgccgca tggaaacttc ctaacctgga tgaatatcct
     1321 gccatcaatc ctccgtatgt gaccccggat atggccggca actggactcc ttaccaacgt
     1381 aatccggaaa caggcgtacg ctactgggct actccgggaa ctgaaggatt catgcaccgc
     1441 atcggtggtc ttgaaaagag caacgaaaca ggcgttatct ctaccgaacc ggaaaaccac
     1501 aataagatgg ttcatctgcg tcaggccaaa gtggataaga ttgcagacta tatccccgaa
     1561 ctcgaagtat tgggtgacga ggacgcagac ttgctgattg ttggctgggg cggtacttac
     1621 ggacatctcc gtctggctat ggactatatg cgcgaacatg gaaagaaagt ggctttcgct
     1681 cacttccaat acatcaatcc gctgccgaag aacactgccg atgtgttgcg taaatataag
     1741 aaaatcgtgg tagctgaaca gaatctggga caatttgcag gttacttgcg catgaaagtg
     1801 cccggattga acatcagcca gttcaaccag gtgaaaggac agcctttcgt cacgagagaa
     1861 ttgatagatg cattcactaa attattggag gaataaaaga tgagcgataa agtatatacc
     1921 gtacaagatt ataaatcagg tcagccacgc tggtgtccgg gatgcggtga ccacgctttc
     1981 ctgaattcac tgcacaaagc catggccgaa ctgggaacag ctccgcacga tattgccgta
     2041 atttcgggta tcggttgttc ttcccgtctg ccttattatg taaataccta tggtttccac
     2101 accatccacg gacgtgcagc cgctattgca acaggagcta aagtagccaa tccaaatttg
     2161 actatctggc agatttccgg cgacggtgac ggtctggcaa tcggtggtaa ccacttcatc
     2221 cacgctttac gccgtaatat cgacctgaat atgattctgt tgaacaaccg tatctatggt
     2281 ctgacaaaag gacaatattc accgacttcg gaacgcggac ttgtaaccaa gtcttctcct
     2341 tacggaaccg tggaagatcc tttccgtccc gctgaactgg cattcggcgc ccgcggacgc
     2401 ttcttcgcac gctgtattgc agtagatggt gccgcttcgg tagaagtatt gaaagcagca
     2461 gccaaccata aaggtgcttc tgttgtagaa gttctgcaaa actgcgtgat cttcaacgac
     2521 ggaactcacg ccagcgttgc caccaaagaa ggacgtgcca agaatgctat ctatctggag
     2581 catggcaaac cgatgttgtt cggcgaaaac aaggaattcg gattgatgca ggaaggcttc
     2641 gggctgaaag tagtgaaact gggtgagaac ggtatcacag aaaaagatat ccttatccac
     2701 gacgcacact gtcaggacaa tacactgcaa ctgaaactgg ctttgatgga aggtcccgac
     2761 ttcccgattg cgctcggtgt aatccgtgat gtagacgctc cgacttacaa tgatgctgtc
     2821 gttgaacaaa tcgaagaaat caaaggcaag aagaaatatc acaatttcca ggagctgttg
     2881 atgactaatg agacttggga agtgaagtaa ttcactgctc atcaataata taaaagctgg
     2941 aggaaagata aaacaatccc tttctccagc tttcattata aatacacctc aagtttgctt
     3001 aaaggtcatc ttcagtcatc ccacagcata ctgggcgtca ccccacaagc cgtgatttgt
     3061 ttcatgccat gaaaccattt gtttctcacc gagaaacgaa atgtttcaag cagggaaaca
     3121 aagtgtttca cgccgagaaa caaacagttc caaacagggt tggaactaaa cggttgcaat
     3181 gaaatcaaaa gcgctccatt atctccatac acatacgccc gttatggtaa ggacatttcc
     3241 aaaatccggc tttatcatcc tcacggttga cagtcccatc agccgaaagg ctccagtacc
     3301 attctccatt tgcataatca attaaatact ttttgatgaa ctcccaacac cggacagcac
     3361 gtgacaaaga tagcttgtca ccgaaatgtt gatatagatt catgaatcct accactgttt
     3421 cagcttgtac ccaccaatgc cggtcggcat caatagacga actgtcagtc cgtaattcgt
     3481 aaatcattcc tccgtcggaa agaaagccct ccgcagcagc ttcagccatc tcaacgatat
     3541 acatttctat ttcggtcaat agttggcggt cagcaagtac gagtgccgcc tcatgaataa
     3601 gccacgacgc ttcaatatca tgaccgtaag atataatatg gtaattgctt cgccagttgt
     3661 cgtcaaagaa aagttgcaga tgccttgtgt ccatatccat aatctcatca atgaacaaac
     3721 ggataagatt atgcaaccgg cttttcagca tttcatcctt ccatatccgg aaaagattgg
     3781 tataaggctc aagaatatgc aaatgagtat tcatcgtttt gcgttcatta gcatccttgt
     3841 cactgagacg catatctgct atttctcccc attctctgga aaacgcttca taatacccat
     3901 tttttccttt gtcaaaacaa tgcaattcga tgtcatgaaa aaggcggaca gcatattcca
     3961 aagcctcgtc gtccgccgtt gcccgatgat actcactcag tccataaata gcaaatccga
     4021 tagcatagac ctgcttcttt gtatccaaag gctgcccatg agcatctatg ctccaataaa
     4081 ctcctccaaa ttgtgtatca taaaagcggt cgattatttc acgtttggcg cgagtggcaa
     4141 tttccagata ttcggtctta tgcaacaggc ggtaagcagc agagaacgtc cacaggatgc
     4201 gtgcattcat gacagctccc ttctccgctt cagcaaccaa acattcctgc cctgtgatgc
     4261 gaccgtaaaa tcctccattc cctctatcct gcattttttc tatccagtaa gggagaatat
     4321 tagtggtaag cacttgttgc acctcctctt tcaggcgttc aatagtagtt tccataatcc
     4381 taaatgttta atgttggttt ctcttctgtt ccagttcccc gatgatttct ttcattcttc
     4441 tttcggatag cggatacatg ctgataaata aaatactcaa taaggtacct atggcaggca
     4501 aaaagctgag aaacatcctg ataccattaa tagcctggtc attttgcacc acattcgcct
     4561 ggaaaccgaa gtaccccaac aaccagccag tgacagcgct gccgattgcc cacccgaact
     4621 tctggctcat ggatgaagaa gaaaatatca gtccggtagc cctgttaccc gttttaagtt
     4681 cggaatagtc tacacaatcg gcatacatgc tccataaaag aggaaaaata ctgccggcac
     4741 aaatactgat aagtatctgg aaaataaaaa tgagtacgag attctcttta tcgaaccagt
     4801 agaaaacgat actgagcacc gttgcaacta ccatagccca catataagtt cttttcttcc
     4861 cgatacggtt actgaccgga gcggccaaaa ccactccgat aatattagcc gcctgtccaa
     4921 tagccaggta cagtccgctt aatacaaatg ggatacctag aaaagtaacc ggctcattac
     4981 tgttttctac aataaagtac ttgaaataat acacagtggc accgtcacga atggaattga
     5041 aaatcaaggc agcaataccc gctcccaaca aaatccacca gggacggttg tgcaacaaat
     5101 ctttcaaatc atctttcagc ggggcttgct tctcccttat aggtttcaca cgctcacggg
     5161 tcaaagcaaa acaaccgata aaaaagacag tacacatgac agcaatcaca gttacagcca
     5221 tttcccaacc atattgctca ccatgtccct cgctaaaagc attcaccata ggcatgaaca
     5281 gcagcaatgc gatgaaactg cccaaatagg caaataccat gcggtagaca gacagtacat
     5341 tgcgatcgtg cggttcggca ctcattacac ctaacagaga agcataaggc acattgatag
     5401 cagaataaac catcatcatc agtgagtaag taatataagc atatacaatc ttcgccgtca
     5461 tgctccattc gggagtagta aaagtaagga ttccgatgaa ggcaaacgga aaagcaagaa
     5521 atagcagata agggcggaac ttcccccacc gtgaatgagt gcggtcggca atgattccga
     5581 caataggatc gaatgccgaa tcccatacac gagtgacgag gaacatagtc cccacaacgg
     5641 ctgcagacat cccgaataca tccgtataga atatcataag ataagagccg aacaacttcc
     5701 agaacataga ggaagccatg tctcccaaac cgtagccaat cttttctttt agttttatca
     5761 tggtagaccg ttatttaagg atgctgtgca tcaactcatc aatttcaggt ttttcgcaat
     5821 ctggcgtttc agtatttcca cagaagcaga tgaagaataa ccgtcttgcg gagtattcag
     5881 acaataatcc accaatcggt ctatggtaga agttgccaca tgcatacgtg tatcactcga
     5941 agcgtaataa atgaatactt ttccgtcttc atctgcaatc cagccattgg aaaacagtac
     6001 attcgaaaca tctcccacac gctccccgcc ttcgggaacc atgattgccc cggcaggaga
     6061 agctatcaca cgcgtcgggt cttcaagaga agtcatatac atataaagaa cataccttaa
     6121 cccggcggca catccgcgaa ccccatgtgc cagatgcagc caccctttag gagtcttgat
     6181 aggatgcggt ccttctccgt tcttcacctc tttgatggta tgataatagc gccggtcaat
     6241 aatcgtttcc tctcttacct ccgcatgagt catatcgtcc accaatgccc agccgattcc
     6301 ccctccgctt ccggcatcga tgaatccgtc ctgcggacgg gtgtaaagtg catatttccc
     6361 attgacgaat tcgggatgaa gcacgacatt gcgttgctgg cttccggtct tcaaatcagg
     6421 cagccgctcc cagttcacaa aatctttggt acgagctatg gcagcagtgg cagttgccga
     6481 cgacaagtcg cccgccggcg ctgccgggtc atgtctttcc gcgcagaaaa tgccgtacac
     6541 ccagccgtct tcatgcgccg taaggcgcat atcataaata ttggtagccg gaatcacatc
     6601 ttcgggcatc gtaataggat aatcccaaaa acggaaattg tcaatgccat taggactctc
     6661 ggccaccgca aaaaacgatt tacggtcggc accttccaca cgtactacca acaggtactt
     6721 gccgttccat ttaatagcgc cggaattcaa tgtagcgttc atgccgatac gctccatcag
     6781 ataagggttg gattcagaat ccaaatcata acgccagaag acaggagtat gggcagccgt
     6841 cagtatcgga tacttataac gggtgagaat accgttaccg tcttccaaag gcacattctt
     6901 gctggtaatc agtttattgt aatcatcaaa cagagtattc aacttctctt taaatgtaat
     6961 catatcaatc gtcaaattaa atgtcgttat tctcttatat atattcactt aacctcttcc
     7021 agataaagta cccgactgga ataatcactc aacttatggt aatccacttt gtgattataa
     7081 ggcatttcca gcccgttcgc catcagatac gcgccgctga aagcttttcc ttcgtaatcc
     7141 agaggctggt tgtctatcct gttcagctcg gtcaccttat aaatcttatc cggatgaagc
     7201 cccgccatcc tggtacgcgg caaatgctga ttgcaaaaat gctcggtctt ccaccaatag
     7261 aacacagcct tctctttttc cggtgcaaca tacatcagcg aagctgcccc cagcctgtca
     7321 tacggagaaa gcaaccggta aatatctccc aactgtacca caggacgaat cattttataa
     7381 tcagcaatag ctttacggca tagctctttc tcttcgcctg tcatattctt gggctgtatt
     7441 tccattccca aacgaccgct catagccaca tcgatacggt atttcaaagg aatggtgcgg
     7501 aaagtctgat gattgggcgc agcactgata tgtgaagcca tagctatagc cggaaagaaa
     7561 taagaggctc cccattgcat ataaattcgt tgcaacgcat ccgtattgtc actcacccaa
     7621 aactcatcaa agtaaggaag cactccataa ttggcacgcc cgcctccact ggcacacgcc
     7681 tgtatggtga gttccggata tttggcacgt atccggcggc aaacattctc aaatccccga
     7741 tgataggcaa tatacagatg actttgttca tccttcggca gatagtccga cccatgattc
     7801 ataatagcca tgttcgcatc ccatttgatg taatctattt ccggataatt ggtcatcaaa
     7861 gtgtctacaa gattgaatat gaaatcctgc acctgcggat tacccaagtc aagcaccacc
     7921 tgcgtccctc cacgccccaa taccggttcg cgcaagggag ctttcaatat ccattccgga
     7981 tgtttttcgt aaagttcact agtggtattg gccatttccg gttcaatcca tataccgaac
     8041 ttcaccttat attggcgggc atcgtccacc aatttacgga taccaccggg cagcttcccg
     8101 gtatccacct tccagtcgcc caatgaagaa ttgtcagagt tacgtttgta tttatcgcca
     8161 aaccacccgt catccatcac aaacagttca ccgcccatag atgcgatatc tcccatcatc
     8221 tggttcatac cgttctcgtt gatatcaaaa tacactcctt cccaactgtt cagcaatatt
     8281 ttacggagag aatttccatg cgccagtttg tatttgcgcg cccaacgatg aaagttacgg
     8341 ctgcatccgc tcaacccttc agcactgtaa gtcaatgcta aagccggagt tatgaaaagt
     8401 tctcctttct tcaagttata aactgaattt tcttcattta tgccggcata aaactggtga
     8461 tattcactat cgtccgtatc aatgcgcagt ttgtagtttc cgccataaca aagagctgca
     8521 ccaatgacat tgccatagtt ctcctgaggt ttcccgtcaa gcgagaacat cacctcggca
     8581 tgtgccgtat gtgaatttct cacaccgtcc cggttcttta tcactttcat gcccggttca
     8641 agaggttcct gcacaagcct tccctcgttg gcccatgagc catacagact tgataaccat
     8701 acatctcccc ttctcacagg cagaaaagcc gaatcaaact tacgtaacat aacgttcttt
     8761 ttctccgcat gggctatctc cgtccaagtc tctatgatat cgacatcgga gtaggccttg
     8821 tagcacacat tcacagaaaa cggatagacc ttgtctttca gtttaatgac agcagtaact
     8881 gctccgtcag tgttctttat ttccgtacca gccacttcca tttgcaaagt catatttccg
     8941 tcggcatgag tcactgccag cgccgactca cccgggcagt tcataccata taccggataa
     9001 gccccatgtt gcatggtagg tgcattataa acttcgcgac agtcattttc agtaagctta
     9061 ctgccataat atacatactt caactctcct cccgccggag ccgagagcac cagtgaggta
     9121 cgaggggttg acaaatgtat attttgggca gccaggtctc ctgttacaaa caaaagcata
     9181 gtaaacaggc agattctaat caggttcttc atcatgtttc cttatttata gagttcaaaa
     9241 ttgtctccga caaacaatat tttcggagac cgactgaatt tcacaaaatc atcggcagat
     9301 acttgtccgg gatagggagc ataataatga gtggactttt cacgcgcatt acgccaaacc
     9361 agtacataac tgaggggata tttctcaatg acaggcaaca gagtccctgt ccaccataaa
     9421 gaatcgggaa tgccttccaa tcctgtttcg gtcagggcaa taggcttatc gtgcttcttg
     9481 cccgcctcgg tcagaatcgt cagcatcttg ttcaattgct tgatatactg ggaacgttca
     9541 aactgatata catccgtacc gagaacatct ataatatcat cccccggata gcgttcaaga
     9601 tattcctcaa ccgtatcaga ttccattccc ggagagtaag ctaacagcac attattcact
     9661 cccttcagac gcaaacggtc attagtcatc cgccaaaggg tcttgtactg ttccgaagag
     9721 cacaaatcct ttccccacca aaaccagctt ccggtatgtt catgccaagg gcggaacacc
     9781 acaggaatga gtacaccctc ctttgtcttc agcgaaagca ggaaatcggc cacacggtct
     9841 atccattcga gcattttcac atggttctct cccccttgca tgacagaagc cactacggtg
     9901 ctatcggtca catcccatga gtcaccgccc gttttcggat tacgtacatg ccaactgagc
     9961 gaaatcatgc cgccacgggc atactgctcg ataatatatt cacgaagatg cgcaaaggat
    10021 actttgtcaa gattatgtgt tcctccgagt tcaatctcgc ccaaatcgaa agacatcacc
    10081 cccggatagg caccgcagac acttttaaca tcgctacgac ccttatctcc ttcccaacct
    10141 attccgtaag cagtatcatc atgatgaccg aaaaggatgc ctttccgttc cgcctgtttc
    10201 aagttttgca acaaggcaac tgtttccgga gttttttcac cggtttctcc acttccgcta
    10261 catgcagtcg gcaagaggag gcaaaatatc gcattaatag tcagaataat atatttcatc
    10321 ataaaagttg aatagtctgt tatttaaacg aaggcaaatc actacggcaa atcacaccag
    10381 gctggccgaa agcgttgttc caccaagcct tgtcggcatg ttcgtgctgt ccggaattaa
    10441 aaacaggcgc agtagtgtcc tttgtcactt cataatcata ccaagtcatg aaccatgccc
    10501 attgggctcc ggctgccagt tgcttgtcta tggttgccac atcaccacat tcgctaagtg
    10561 caatcagctt gtccgggaaa gcttttttta gtgcatcaaa atccgttgcc agtccggcag
    10621 cgctggtctt gtggtacacg tcccgtccga taatatccac gtatgcatca ccaggatacc
    10681 agtccctgtc gttcgtttca ctagtccata cccagataag attgttcagc cctttctgct
    10741 tgaaagtctc atatacgagt ttccagagcc gtttgtatga agctgcatct ttcccccacc
    10801 agaaccattt gcctgcagct tcgtgcaacg gtctccaaat tacaggaata ttcttctgct
    10861 tcaaaagcag taagtaaccc gccaattctt ccaaatcggc tttaatgatt tcattttccc
    10921 gggttccctc ctgcaatgcc ttggtgatgt caaaatccgt ttcactaatc atacatttat
    10981 actcactgct attttccgtg accggcacat tccaatgcca gcaagcagca accaatcctc
    11041 cggcattcca ccagtcttca acaaccgata tcttattata atcaatccag tcggccggtg
    11101 aagcgggaag gttcatgtaa tcaaagcagg caatggcagg atacttcccg gtctgacggt
    11161 ttacccatat tgcttcattg acgttccatg tcacgttcgc cattgtactg ctcaaagttt
    11221 ttctccccca gcagtttctc agatatgtat acactttctt agcctcaacg gatgcacctt
    11281 cggtgcaaag ttctttcttt atcaatgaat tgtccaccgg ttccgactcc ggagccggaa
    11341 agtcttcccc ggacgaggaa gagcatcctg ctcctatgcc gcaaaagatg aaataaatca
    11401 aaaagttata tatattcttc atacctattt tctataatca tttaccggat tttcttctca
    11461 atacggatat tggcgaaact gtggtctacg ttccaatccg aattaggttg gagaatgaat
    11521 gacaaccctg tccatccttc cgagaaagca ttacccgaca cggtctgcaa atcaatcgaa
    11581 acagtacacc acttcccgta agtattgaaa ctgccattcg cagaaggatt ccacggataa
    11641 ttgccattat taagctgaat cagatagcca tatccagccg aatcgtagaa cggatgtccc
    11701 gtaggagagt aaacctcaaa cttaaaattg taatcggcag gagctgccgc cacatcagcc
    11761 ggacagttga atcctccgca aacaagattc gtccaattcc aggcaccata actgccggtt
    11821 accctaaaat aaggtccata gagaatttcg ggctcattgt cgcctgcttc attgatgata
    11881 agttctttgc ctgcccagag tccgtaatca tcaggatgag aaaggttcca gataatcgca
    11941 tccgtcatac gataagggat tttttcggta tgtgcaacag aacccgctcc catataactc
    12001 acttcgatga cagagttatc ctgagcatct tcaggaatga caactgacat atatttgtcc
    12061 gagatggaat ctacctcaag ctcgacacca ttcattttga cagtagaagt ggaattcgcg
    12121 cctccgaacc catagaggtc gaagtattta cctttcagct gtacagatgt gccgggaaga
    12181 gcaaactcat tatatagacc gtccacctga accaagggta cagacaccgt gaaatcataa
    12241 gtggtacttc ccaactccgt ttcataatag agcttattat tcacttccaa cggaatctga
    12301 cggggaatgg gaagataggc actgctggca gtcgcatata cctcaccgac aggaagttca
    12361 acatcattga acatcacttt cctcacacgg cttaaattgg aaccgtcgag tacaatcatc
    12421 tgctccagat ttccgtcagt gattggcaac aatttatccc tgtctttgga gtcatacaca
    12481 gcgtcaataa cgggggcacc gcttgacgcc atttcgtcat cataattatc attataggtc
    12541 actatgtcct gacaagcacc aaagctcaac gccatacagc acataagagt tatggatttg
    12601 aaagataatc ttttcatgaa atattgattt taaatttctg actttattct agaataggga
    12661 aggcacttta actccaaccc ggattattgc tgtcaatcgc ttcattagta gaaacctcat
    12721 cagaaggcaa tggaaagagc aaatgacgct gttcacgatg tttgttcaca ccggcttcat
    12781 cgtagtgggt ttgagaaccg tccttgttga ttccgccgat agagttcatc acttccacat
    12841 agattcccca acgaatcaaa tcccatcgcc tgtctccttc cagcgcaagt tctttggcac
    12901 gttcttcaaa aatggcggaa cgcagggctt gtttggaagc aatggctcca tcaccggaac
    12961 ttgatgcaag agtggcattc gaacggatac gtaccctatt caatgcactg atagcctccg
    13021 aagatactcc attatccaat tcacatttcg cttctgcgta aatcagcacg atgtcagcca
    13081 gacgaaggaa aggccagtag gcatccgatt ttttctgtgt ggcgtctgta acgtctgcat
    13141 atttgttggt gaatgccaga cactcgttcg atacgttaaa gtaatagtta cgtccgtcgt
    13201 tgtagggagc ttccggttct gccacataat ttccgttagc atcatagcct gtggccttca
    13261 gcacgtactc cggcgtattc ggatagaaaa agccgctctt cggttttccc tcttcgtcct
    13321 gatagcttac tataaaacga tgtttcactc cttgtgtgac acggtaatcc tgagaggtga
    13381 acagagtata ccagtgataa cggttgccga tatacagacc gctggccact acaccgcgtc
    13441 cattgtcaat cccattgtac cattcaaaga tactgtttcc ataaagttca tcaccgttgg
    13501 caccttgcaa ggcaaacaga tgttcggtac tttgccccag tccggaacgc ttccacagtt
    13561 ggtcataagg aagcaggtca tggctgccgt agttgttgtc cggagtagga tagagcagat
    13621 atcccgccca tttggcagct ttttcatagc aatccctcca atcgaaactc tcgtaacctt
    13681 tcacctgagt ctttacaaac tcccgcctta caggcatatc caagacttta tcgtcaccat
    13741 tgtatgaata agacgaaccg gtcatcactg tcattttctc acctgcagga agtgcaccgg
    13801 aagccatggt tgcatatact ttagcgagca gtccgacagc tgttcctgca catacatgtc
    13861 ctgtctgata ctccgcatcc gtattcttat aaagacgggg aatggcttcc tcttccaaaa
    13921 gacgaactat ttcagcatag acatcggcta tcggacggcg aggattgttg tatcccgtcc
    13981 cgtccgtgac agccctgtca aacaacggga tctcaccata cgcctttacc agcataaaat
    14041 aggcaaaagc cttttggaaa tacacctcac ccagaccgtt cgtctttacc cgttcatcgg
    14101 cacccgtgat tgcattgata tatttaatag ccacattagc gcgattaatc aagttatagc
    14161 aacccttcca aatggtattg gtcacatcat ctccctgata attgccggca cctgcattgc
    14221 tgaatgccca gtcagggccg gaagcatagt cacagtccat atcaagcacg cgggggaaat
    14281 tcccccaacg gaacatatcg tccgcccatt tactgtacac gccggtcacc cattggctga
    14341 ctgcagcatc atcgttgccc acctcttccg ggcccacaaa agaatatggc ttttcgctca
    14401 agaaatcctg gcaagcggag aaagttgtca tgcctgctaa agaaagagat aacaggatat
    14461 atattttttt cagtttcatg gagttacatt taattgttta tcatcttaaa aatctacttt
    14521 tatgcccaat gagaatgtgc ggctgctggg ataggaatac acatcaacac cacgccggga
    14581 ggcatccgaa ccgaaagcat tcacttcggg gtcgaaccag ctatagccgg taatggtgaa
    14641 gagattggtt gcgctggcat acacattgac attgctgata cctttgaaat taggtttcca
    14701 gacatacccg atattcaagc ttttcagctt caagtaagag ccgtcttcta cataacggtt
    14761 agagataagc atattacgtt cgtagcccga aacggctttc ggccactttg cctgggcggc
    14821 attggcttct gtccagcggg tattataggc ttcatgggtg atattaccca cattccccat
    14881 cttcatatcc atcaggttgc cattgaaaat gtcgtttccc tgacttcctt gcaggaaaaa
    14941 gctcaatgta acgcccttcc actcgaagtt gctggtaagt ccataaacaa aatcaggatt
    15001 cgtatctccg ataatcaccc ggtcggccga agtaatatcg ggattatcat caaagttcct
    15061 gtattttatt tcaccaatca taccggcgcc ttttgcgcgg atatctgcac tgggcgaagc
    15121 catcacctct gccagattat catagaatcc atcttctaca taaccatata tagccccgat
    15181 aggacaaccg ttgcgctgta tgaacacctc atcagccgaa ctccataatt tctgcgcaaa
    15241 ctggtctgct ttcagtccgc caatcctgtt gcggttgaac gagatattcg catcgatatt
    15301 ccatttcagc ggtgtattct gcaacacata gaacttaccg gtcagttcaa gcccttcatt
    15361 agtgatgtgt ccgctattga ccatcatgct accgaagccg gtacttgaag ggattttcac
    15421 atcctgaagc aaatcgcgtg ttttcttatg ataataatcc accgtcaggt taatacggtt
    15481 attcaagaat cccatatcaa ttcccacatt atattgggca gtcgtctccc agcgcaagtc
    15541 atcggaaacc gggcctctcc agtccacttc ggcaaagccg ctgttgatag ccccgccaaa
    15601 aggatagttt gccatattaa gcattggcag cgtacgataa cttccgatac cttggttacc
    15661 cgtttcacca taactcaggc gcaacttcaa gttactgaat atccccaaat ctttgataaa
    15721 cttctcttcc gacatacgcc atgcaacagc tccagaaagg aaactagccc acttgttctt
    15781 atcggtaaac ttactcgaac cgtcagcacg acaggatgca gtaaggatat atttatccat
    15841 gagagtgtaa ttgacacgtg ccaggaatga agctaaagct gcatctcccc tgtcagacct
    15901 caatttgccc ggattagctc ccaaactcat atcgaaatcc tgagtgatgt cgttgggaaa
    15961 tcccgtggcc gacattgctt tgcttcccca actggatttc tctgccgtaa aacctgccac
    16021 cgcattaacg ctatggatac cgaacgtctt atcgaacgtc agcagtgatt cggcggtgat
    16081 tcccaaccac cagttgcttg actgttcggc cttgccattg atattagtag tggacgaacc
    16141 ttcctgcgtt tcgcggccat agtacatgcc acggtcattg ttagtataac tgatacccaa
    16201 attctgtctg aacttcagaa aagacaaaag tttaacctcc atatagcttg aattgaacac
    16261 atttatgctg cgcaaattat cttttgtgtt ggttatataa gccaacggat tagatgcaag
    16321 ccagctcaat tcaccagttt ccgccttatt cttctgcgga tcatacgtcg agggaaacac
    16381 caatgcagaa cggataacac cacaatcaga agagttggtc ttcgagaaat ccgtatcagt
    16441 atgtgtgaaa ctggtattca tgcccatttc caaccatttg gttatatacc tgcctatatt
    16501 ggaacgtaat gaataacggg taaaaccgga attcttgatg ataccgtcct gtttgaggaa
    16561 attaccggag aatgagtgcc aacccttgtc cgaaccgccc gatacactga tattatattc
    16621 ctgcgaaaag ccgttctgat aaatcaaatc ctgccagtcg gccaccccca cataggaaat
    16681 gttaccatat tcatctacat aatcacccgg tcggaggaag tcttccggtg ccggcaggta
    16741 tttgccagca gaagtatcgt ttccgccacc cggcaaggcc ggatattccc aagccccggg
    16801 atacggcagc ttgccataag gtttattact atatttataa tcattaagca cttgttcgtt
    16861 ttgataattg gcataagtga atgcgtcgag cacatccata cgtttcgcta tcttcgagaa
    16921 tgtaaagttg gcactgaatt ccaccttttc atttcccttc tcacctcgtt tggtggttat
    16981 gataacaacc ccgttcgccc cacgggaacc atatatggca gtcgcggaag catctttcaa
    17041 gacatcaata ctctgaatgt cgtgcggatt gataaatgcc aatgggtttg atttattctg
    17101 actgttattt gtgtcactgg ctggggtatc tcccgtatca aacggcacgc cgtctacaat
    17161 ataaagaggt tgtgagttgg tagagaaaga gttcgtaccg cgaatctgaa tactgatgcc
    17221 gccccccgga gcgccgtcac tctgattcac ctgcacaccg gcaatcttgc ccgccaaccc
    17281 cttactcaaa tcagtaggat tgcctttcat caggtcgtca ctttttatct gcgaaacggc
    17341 accgctcaaa tcacgtttct tcattgtacc ataacccact acgacaacct cgtccagcag
    17401 ttccgcatca tccttaagaa caacagtcac ctgggcctgt ccgttcttta aggatacttc
    17461 ctgctgctta tagccaataa agctgacctg taaaaccgcc ccttgcgaaa cggttaatgt
    17521 aaaatcaccg ttcaaatcag tgatagttcc gtttgtcgta cctttctgta ctacatttgc
    17581 accaatcacc ggttctcccg aagcatccgt cacccgtcct tttattttaa cggattgctg
    17641 ttgtatcatt gctgtcgtgt cggcagacgc attagcggga agaggaacac cactaaccag
    17701 agatgccaag cagagccctg tgataaatac tgtttttctg gattttagat tcataatata
    17761 aatatttgat aggtttttat tctgtcgatt taaggacttc cttttgactg tggcaaatgt
    17821 acgaataaaa aagtaccgcc tatttctcat ttgattttca aactatccga attgtatccc
    17881 gaccggagaa taatcgattc gggatagaaa aagatacaaa agacacatat cttcccctaa
    17941 aatgatacat tcgggataag ggatttatga acggaattct taacttagca acgtgaaaag
    18001 atacaattat gaaaagacac ttacgaattc ctttgtttct tcttatctcc ttgctgaata
    18061 gcctggcatc atacgcttca aacgaaatga gttttcacca gctgggagta aaaacaggca
    18121 tgtccgacaa ttatattcag gcgatagaac gggataaata tgggttcatg tggtttgcta
    18181 cccgtgatgg cctgaaccgc tatgacgggt atcatttcaa gacttatacc accctccggc
    18241 aaggagctta caacaatagc gtagaatggg tagcagaaga tgcagcaggc aatatatgga
    18301 taaaaactcc ggttaactat tgtttttatg accgtgaaat ggacgaactg gataacagaa
    18361 cggagcttct tctgcacaag ataggtatct ttgaaagccc caggcaatta ttcatagatg
    18421 acgacaagaa cctgtggtgt gttgcagaca acacattgta ttactacatc ttctccgatg
    18481 aaacgctgta caaacagtca cttccgggca gcgtaaacat tgccgacatg gcatgccgca
    18541 acaaaagatg ttacattctc atgaccgatg gaaatgtaat taacatagac tggatgcata
    18601 aatccataac caaactgttt catacggaaa tacataccac ttatgtgcct cacatttatc
    18661 tggacttttc ttcccagctt tgggtgtacg ccccgcacag cgcggatgtc aaatgttatt
    18721 ctctgacaga aaacaactgg attgactttg ccgcccgaac ggaactcagt agagaacgaa
    18781 ccatgattac cacaataacc gacgacggca aagggaatat ctggatagga accgatggca
    18841 gaggaatatt catatgcccg tatgataaag aaaagggcaa ggtgacgcgt ctattcaagg
    18901 atgtcgacaa attatattcc ctgccggaca atcacgtgac ctatatctat aaggacaacc
    18961 gcgacgtgat atggatagga accggcaaac agggcgtagc ctattcaggt ttgaacaatc
    19021 tgatattcga aaaccattat tgtccccaac tggaggatgt cagttgtttc tacgaagacg
    19081 gagagggcaa actatggctg ggatttgacg gtgaaggcat agccagttac gacaaggata
    19141 aaaacaccta tacttattat aaatcaaaga acaaagaaat tccttccgac ttgattgttt
    19201 gttctttcca tgacaacaaa ggcagagtgt ggtggggaag tttcggcggt ggagcgtttt
    19261 attatcagaa cggccagttc actccgctca aagcggcgga aaataatccg gtggaactgc
    19321 ctcaatacat acgtcgtatc acacaggata atgccggtaa cttatggttt gccacttact
    19381 cgcaaggact ctactgcctg gaaccttccg gaatgctcaa agattataca atgagtaatt
    19441 caactttact gaccaattac attgccgacc tggcatatgt tgatggtcat tctctttatg
    19501 tggctaccag ttccggagtg taccacatga atacttccac ccgggaaatg acgatattgg
    19561 aacaaactgc cgacggtgaa gaagtgatac aagataagtt cgccaattgc atctatcaag
    19621 attcacgcgg actactatgg ataggcggac ggaaaggggt caatgtgtat agcccgaagc
    19681 aaaataagtt aatcaatttg aataccgcaa acggtgtttc ccattcatat atacgtgcca
    19741 ttatcgaaga tgcatctcac aatatgtggc tcactacaga ccatggcatc acccacgtgg
    19801 aagtagtgga atccgatgct accagtatgc ccgacttccg ttgccaccct tattatgaag
    19861 aggatggaat cggtaacctt actttcaata atttttcaat cttctgcaat cacaggaatg
    19921 aagtaattgc cggaggcgga ggaggatacg taaaaattat cccacgcggc aatgacttgt
    19981 tttacttcga ccgccaagta atattcaccg acttatatat tgataatgag tgtgtcaatg
    20041 caaacaggcc cgcacacaac ggacgtatca ttctcacaaa gaacatccag ttgcttaaca
    20101 acctcaacct gaactattca gacaacagtt ttgctgtgga agtctcggct atggactatg
    20161 gcaatctgca caagctacaa tacgaataca gactcaataa aaacgaagaa tggacaaagc
    20221 tggagggaaa ccggatttat ttcaataaac tggctcccgg aacttatcaa cttcaagtac
    20281 gggtaatgaa ggttcatgat tatgaaaacg atgcaagtgc tacactttcc atcaatgtgt
    20341 atccgccatt ctggctttct aatatagctt atagcatcta tgcattactg ttggtgagtg
    20401 ccatatcact tatctttatc cacatgaaac ggaaacaccg tcgattattg cttcaacaaa
    20461 aacgtgatat ggaaacggtg cagcagcatg aaattgacga agccaaatta cgctttttca
    20521 ctaatgtaag ccatgacctg cgcactcctt tgtcacttat catcactcct cttgagcaaa
    20581 tattggctac taatacggca caagacataa aaaaggaatt gaagttgatt catcgcaatg
    20641 cattggcact cctggacgtt atcaaccaac tgcttgattt acgtcggctg gataatggta
    20701 aagcccaact caatccttcc cacggtgatt tggcagattt catcaaagaa gtatgtgatt
    20761 ctttctattc gtacggcgac aaaaagaata ttgccttcag cctttcattg aaaaccgata
    20821 atctggaaac agactttgat aagaataaaa tgcagcgcat aatgcttaat ctattatcga
    20881 acgcattcaa atacaacgtg aatcacggaa gcgtgaacgt agtgctggat cgtatcataa
    20941 aagatgaaag agaatatgcc tgcatccaag tggcggatac cggaatcggg atacgtgaag
    21001 aaaacaaagc taaaatattc gaccgtttct atcaagaaga gcactcatcc actgattata
    21061 tcggcagtgg cataggcatg catatagtca aagaatatgt tactctccat aatggcgaca
    21121 ttcaaattcg cgataatcat ccccaaggta ctatctttga atttatgttc cccatacgac
    21181 atgaatgcaa gaacataaat cccacggcaa cgccaactga aagaccagac atacaggaag
    21241 aaccggagca agcaaaaacg ccaacaggtc gttcattact tattgtggag gacaacgaag
    21301 atttccgaca attcattgtt gactgcctga aagaccgatt tactgtttat gaggccgaac
    21361 aaggtgaaaa agcaatggag atattggccc tgcatgatat cagccttgtg ataagcgatg
    21421 tccgtatgcc gataatgaac ggactggagc tatgtaataa gataaaggga gacttccgtt
    21481 actcacatat ccctgttatt ttactaactg cacgaaccgc ccaggaacat atgctggaag
    21541 gattgcgtga aggtgccgat gactatataa ccaagccttt caatctggat attcttctac
    21601 tccgtatcca aaagctgtta gaatggagta gccgcaacca tcaacgattc ggaaaagttg
    21661 aagtgtctcc tgccgagatt accatcagca ctattgatga aaggcttatt gagcgagcca
    21721 tacaagcagt ggaagagaat atggacaata cagatttctc tgtcgaagac ctaagcatga
    21781 ctgtcggaat gagtcgtggt cacttataca aaaaactaat gacgataaca ggcaagtccc
    21841 ctcttgaatt tatccgtgtc ttgcgcataa aaagaggaaa gcaattatta gaacagagtc
    21901 aggaaagcat ttctcaaata gcttatcaag tgggactgtc acccaaacaa ttcgctaaat
    21961 atttcaaaga agagttcgga tgcctgcctt cagaattcaa ctgtaaaaag gactgattcc
    22021 ctataagaaa gcatgctttt gttgcaatga aaaataaaag atggagaaag aaacttgatt
    22081 ccctttcttg ttacagtcaa
//
