LOCUS       AE005176               13187 bp    DNA     linear   BCT 30-JAN-2014
DEFINITION  Lactococcus lactis subsp. lactis Il1403, complete genome.
ACCESSION   AE005176
VERSION     AE005176.1
DBLINK      BioProject: PRJNA72
            BioSample: SAMN02603339
KEYWORDS    .
SOURCE      Lactococcus lactis subsp. lactis Il1403
  ORGANISM  Lactococcus lactis subsp. lactis Il1403
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Lactococcus.
REFERENCE   1  (bases 1 to 13187)
  AUTHORS   Bolotin,A., Wincker,P., Mauger,S., Jaillon,O., Malarme,K.,
            Weissenbach,J., Ehrlich,S.D. and Sorokin,A.
  TITLE     The complete genome sequence of the lactic acid bacterium
            Lactococcus lactis ssp. lactis IL1403
  JOURNAL   Genome Res. 11 (5), 731-753 (2001)
   PUBMED   11337471
REFERENCE   2  (bases 1 to 13187)
  AUTHORS   Bolotin,A., Wincker,P., Mauger,S., Jaillon,O., Malarme,K.,
            Weissenbach,J., Ehrlich,S.D. and Sorokin,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JAN-2001) INRA, Genetique Microbienne, Domaine de
            Vilvert, Jouy en Josas 78352, France
COMMENT     On or before Feb 26, 2009 this sequence version replaced
            AE006239.1, AE006240.1, AE006241.1, AE006242.1, AE006243.1,
            AE006244.1, AE006245.1, AE006246.1, AE006247.1, AE006248.1,
            AE006249.1, AE006250.1, AE006251.1, AE006252.1, AE006253.1,
            AE006254.1, AE006255.1, AE006256.1, AE006257.1, AE006258.1,
            AE006259.1, AE006260.1, AE006261.1, AE006262.1, AE006263.1,
            AE006264.1, AE006265.1, AE006266.1, AE006267.1, AE006268.1,
            AE006269.1, AE006270.1, AE006271.1, AE006272.1, AE006273.1,
            AE006274.1, AE006275.1, AE006276.1, AE006277.1, AE006278.1,
            AE006279.1, AE006280.1, AE006281.1, AE006282.1, AE006283.1,
            AE006284.1, AE006285.1, AE006286.1, AE006287.1, AE006288.1,
            AE006289.1, AE006290.1, AE006291.1, AE006292.1, AE006293.1,
            AE006294.1, AE006295.1, AE006296.1, AE006297.1, AE006298.1,
            AE006299.1, AE006300.1, AE006301.1, AE006302.1, AE006303.1,
            AE006304.1, AE006305.1, AE006306.1, AE006307.1, AE006308.1,
            AE006309.1, AE006310.1, AE006311.1, AE006312.1, AE006313.1,
            AE006314.1, AE006315.1, AE006316.1, AE006317.1, AE006318.1,
            AE006319.1, AE006320.1, AE006321.1, AE006322.1, AE006323.1,
            AE006324.1, AE006325.1, AE006326.1, AE006327.1, AE006328.1,
            AE006329.1, AE006330.1, AE006331.1, AE006332.1, AE006333.1,
            AE006334.1, AE006335.1, AE006336.1, AE006337.1, AE006338.1,
            AE006339.1, AE006340.1, AE006341.1, AE006342.1, AE006343.1,
            AE006344.1, AE006345.1, AE006346.1, AE006347.1, AE006348.1,
            AE006349.1, AE006350.1, AE006351.1, AE006352.1, AE006353.1,
            AE006354.1, AE006355.1, AE006356.1, AE006357.1, AE006358.1,
            AE006359.1, AE006360.1, AE006361.1, AE006362.1, AE006363.1,
            AE006364.1, AE006365.1, AE006366.1, AE006367.1, AE006368.1,
            AE006369.1, AE006370.1, AE006371.1, AE006372.1, AE006373.1,
            AE006374.1, AE006375.1, AE006376.1, AE006377.1, AE006378.1,
            AE006379.1, AE006380.1, AE006381.1, AE006382.1, AE006383.1,
            AE006384.1, AE006385.1, AE006386.1, AE006387.1, AE006388.1,
            AE006389.1, AE006390.1, AE006391.1, AE006392.1, AE006393.1,
            AE006394.1, AE006395.1, AE006396.1, AE006397.1, AE006398.1,
            AE006399.1, AE006400.1, AE006401.1, AE006402.1, AE006403.1,
            AE006404.1, AE006405.1, AE006406.1, AE006407.1, AE006408.1,
            AE006409.1, AE006410.1, AE006411.1, AE006412.1, AE006413.1,
            AE006414.1, AE006415.1, AE006416.1, AE006417.1, AE006418.1,
            AE006419.1, AE006420.1, AE006421.1, AE006422.1, AE006423.1,
            AE006424.1, AE006425.1, AE006426.1, AE006427.1, AE006428.1,
            AE006429.1, AE006430.1, AE006431.1, AE006432.1, AE006433.1,
            AE006434.1, AE006435.1, AE006436.1, AE006437.1, AE006438.1,
            AE006439.1, AE006440.1, AE006441.1, AE006442.1, AE006443.1,
            AE006444.1, AE006445.1, AE006446.1, AE006447.1, AE006448.1,
            AE006449.1, AE006450.1, AE006451.1, AE006452.1, AE006453.1,
            AE006454.1, AE006455.1, AE006456.1.
FEATURES             Location/Qualifiers
     source          1..13187
                     /organism="Lactococcus lactis subsp. lactis Il1403"
                     /mol_type="genomic DNA"
                     /strain="IL1403"
                     /sub_species="lactis"
                     /db_xref="taxon:272623"
     gene            complement(1..945)
                     /gene="yufC"
                     /locus_tag="L36511"
     CDS             complement(1..945)
                     /gene="yufC"
                     /locus_tag="L36511"
                     /note="EVIDENCE BY HOMOLOGY BIO15.01 HYPOTHETICAL"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="AAK06076.1"
                     /translation="MKKRQLRRNKNKFKRVSLAFFGLVIILAGALFLFWPKGITSVTKN
                     NDKQTSSISTKTSSSSISNSGKQVIYPTIYITGSGGDVSSINRLVTQLLPMEKAGDKPL
                     VLMSDVQKDYELKVEGNISKDMQYPMIEFGTVAKTDSGSLFSKGLQKAISYLVEHYQVP
                     WINLVGYSSGATGAIYYMIDTADKSNFPPVNKYFSLEGEYNDVTNLVAGETLTDVLKNG
                     PLIKTTMYNYIADNYKKISPKTKMMLLEGDFDTEKQTDSAIPWADSFSIYHLFKKNGNE
                     IIASLYPTKLRHSKAPTNPTVAKYVKNFLYETP"
     gene            complement(1068..2048)
                     /gene="galE"
                     /locus_tag="L0024"
     CDS             complement(1068..2048)
                     /gene="galE"
                     /locus_tag="L0024"
                     /EC_number="5.1.3.2"
                     /note="EVIDENCE BY HOMOLOGY BIO06.12 Sugars. GALACTOSE
                     METABOLISM"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="AAK06077.1"
                     /translation="MTVLVLGGAGYVGSHAVDMLLKRGYDVAVVDNLVTGHRESVPANV
                     RFYEGDVRDQAFLADVFEKENIEGIMHFCAYSLVGESMQKPLMYFNNNVGGAQVILETM
                     EEFGVKHIVFSSTAATFGIPEKSPISEKTPQKPINPYGESKLIMEKMMKWQSQATDMTY
                     VALRYFNVAGAKDDGSIGEAHKNETHLIPIILQTALGQREFITIYGDDYHTPDGTCIRD
                     YIDMEDLIEAHIKALEYLKAGGQSDQFNLGSSKGYSNLEVLETARKVTGKEIPSQMGER
                     RAGDPDELVADSTKAGEILGWKAQNDLEHIITNAWKWHQSHPKGY"
     gene            complement(2100..5090)
                     /gene="lacZ"
                     /locus_tag="L0025"
     CDS             complement(2100..5090)
                     /gene="lacZ"
                     /locus_tag="L0025"
                     /EC_number="3.2.1.23"
                     /note="EVIDENCE BY HOMOLOGY BIO06.12 Sugars. GALACTOSE
                     METABOLISM"
                     /codon_start=1
                     /transl_table=11
                     /product="GH2"
                     /protein_id="AAK06078.1"
                     /translation="MMTMIDVLERKDWENPVVSNWNRLPMHTPMDLLEKQSLNGLWNFD
                     HFSRISDVPKNWLELTESKTEIIVPSNWQIEFKDKSDVPIYTNVTYPIPIQPPYVPEAN
                     PVGAYSRYFDITKEWLESGHVHLTFEGVGSAFHFWLNGEYGGYSEDSRLPAEFDISNLA
                     KEGQNCLKVLVFRWSKVTYFEDQDMWRMSGIFRSVNLQWLPDNYLLDFSIKTDLDEDLD
                     FANVKLQAYAKNIDDACLEFKLYDDEQLIGECHGFDAEIGVVNPKLWSDEIPYLYRLEL
                     TLMDRSGAVFHKETKKIGIRKIAIEKGQLKINGKALLVRGVNKHEFTPEHGYVVSEEVM
                     IKDIKLMKEHNFNAVRCSHYPNDSRWYELCDEYGLYVMDEANIETHGMTPMNRLTNDPT
                     YLPLMSERVTRMVMRDRNHPSIIIWSLGNESGYGSNHQALYDWCKSFDSSRPVHYEGGD
                     DASRGATDATDIICPMYARVDSPSINAPYSLKTWMGVAGENRPLILCEYAHDMGNSLGG
                     FGKYWQAFREIDRLQGGFIWDWVDQGLLKDGNYAYGGDFGDKPNDRQFSLNGLVFPNRQ
                     AKPALREAKYWQQYYQFELEKTPLGQVFAFTVTNEYLFRSTDNEKLCYQLINGLEVLWE
                     NELILNMPAGGSMRIDLSELPIDGTDNLFLNIQVKTIEKCNLLESDFEVAHQQFVLQEK
                     INFTDRIDSNEEITLFEDEELLTVRSAKQKFIFNKSNGNLSRWLDEKGNEKLLHELSEQ
                     FTRAPLDNDIGVSEVEHIDPNAWLERWKGIGFYELKTLLKTMIIQATENEVIISVQTDY
                     EAKGKIAFSTIREYHIFRNGELLLKVDFKRNIEFPEPARIGLSLQLAEKAENVTYFGLG
                     PDENYPDRRGASLFGQWNLRITDMTTPYIFPSENGLRMETRELNYDRLKVRAMGQSFAF
                     NLSPYSQNQLAKKGHWHLLEEEAGTWLNIDGFHMGVGGDDSWSPSVAQEYLLTKGNYHY
                     EVSFKLT"
     gene            complement(5102..5563)
                     /gene="thgA"
                     /locus_tag="L0026"
     CDS             complement(5102..5563)
                     /gene="thgA"
                     /locus_tag="L0026"
                     /EC_number="2.3.1.18"
                     /note="EVIDENCE BY HOMOLOGY BIO06.12 Sugars. GALACTOSE
                     METABOLISM"
                     /codon_start=1
                     /transl_table=11
                     /product="thiogalactoside acetyltransferase"
                     /protein_id="AAK06079.1"
                     /translation="MFSEIGENCFIQPPFYANFGGKNVHFGTEIYANFNLTLVDDTDIF
                     VGNHVMFGPNVTIDTATHPVSPDLRKRGAQYNKKVYIEENVWLGAGVIVLPGVRIGKNS
                     VIGAGSLVTKDIPDNVVAFGTPCMVKRKINDSDFKTYDHGKKIDLDEFI"
     gene            complement(5765..7246)
                     /gene="galT"
                     /locus_tag="L0027"
     CDS             complement(5765..7246)
                     /gene="galT"
                     /locus_tag="L0027"
                     /EC_number="2.7.7.10"
                     /note="EVIDENCE BY HOMOLOGY BIO06.12 ENERGY METABOLISM.
                     Sugars. GALACTOSE METABOLISM"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="AAK06080.1"
                     /translation="MSIYQSIQDFISLALQNGTIEPLDELYHRNQLLHFLGLNDWAEVD
                     KEAHEKDSLILMDQLLAIANENNVIEKGQDEFYEAALMNFITPRPSKINQDFWEKYKTS
                     PDAATQYFYELAQQVNQVKTRDITRNIAFSHLTKYGKLEITINLSKPEKDPKAIAAAKL
                     VKASSYPACQLCLENEGFYGIGNKPARSNHRIIQVSINGEDWGFQYSPYAYFNEHSILL
                     NAKHQPMEINKRAFDNLLGFLDQFPDYMIGSNADLPIVGGSILTHDHYQAGRYEFPMAK
                     AELREEIKLQQFPEVSCGIVNWPMSVLRLSSKNQVELSKAADELLKKWQVYSDESLQIK
                     AKSADGKLHHTITPIARIREGKYELDLVLRDNNTSEIYPDGIFHPHPALHHIKKENIGL
                     IEVMGLAILPARLKTELLEVEKYLLNQENEMSEIHKPWAEELKETEYFSKETVHETVQE
                     AVGEVFEQVLKDAGVFKDNEVGQKGFYEFINFVNN"
     gene            complement(7420..8619)
                     /gene="galK"
                     /locus_tag="L0028"
     CDS             complement(7420..8619)
                     /gene="galK"
                     /locus_tag="L0028"
                     /EC_number="2.7.1.6"
                     /note="EVIDENCE BY HOMOLOGY BIO06.12 ENERGY METABOLISM.
                     Sugars. GALACTOSE METABOLISM"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="AAK06081.1"
                     /translation="MSIVVENSTVLSALTEKFAEVFGDTKEVEYFFSPGRINLIGEHTD
                     YNGGYVFPASITIGTTGLARLREDKKVKLYSENFPKLGVIEFDLDEVEKKDGELWSNYV
                     KGMIVMLKGAGYEIDKGFELLIKGEIPTASGLSSSASLELLVGVVLDDLFNLNVPRLEL
                     VQLGQKTENDYIGVNSGILDQFAIGFGEVKKAILLDCNTLKYEMVPVELRDYDIVIMNT
                     NKPRALTESKYNERFAETREALKRMQTRLDIQSLGELSNEEFDANTDLIGDETLIKRAR
                     HAVYENNRTKIAQKAFVAGNLTKFGELLNASHASLKDDYEVTGLELDTLAETAQKQAGV
                     LGARMTGAGFGGCAIALVAHDNVSAFEKAVGQVYEEVVGYPASFYVAQIGSGSTKLDVE
                     "
     gene            complement(8646..9665)
                     /gene="galM"
                     /locus_tag="L0029"
     CDS             complement(8646..9665)
                     /gene="galM"
                     /locus_tag="L0029"
                     /EC_number="5.1.3.3"
                     /note="EVIDENCE BY HOMOLOGY BIO06.12 Sugars. GALACTOSE
                     METABOLISM"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase"
                     /protein_id="AAK06082.1"
                     /translation="MEIKIRDFGLGSDLISLTNKAGVTISFTNLGARIVDWQKDGKHLI
                     LGFDSAKEYLEKDAYPGATVGPTAGRIKDGLVKISGKDYILNQNEGPQTLHGGEESIHT
                     KLWTYEVTDLGAEVQVKFSLVSNDGTNGYPGKIEMSVTHSFDDDNKWKIHYEAISDKDT
                     VFNPTGHVYFNLNGDASESVENHGLRLAASRFVPLKDQTEIVRGDIVDIKNTDLDFRQE
                     KQLSNAFNSNMEQVQLVKGIDHPFLLDQLGLDKEQARLTLDDTSISVFTDQPSIVIFTA
                     NFGDLGTLYHEKKQVHHGGITFECQVSPGSEQIPELGDISLKAGEKYQATTIYSLHTK"
     gene            complement(9795..10739)
                     /gene="lacS"
                     /note="EVIDENCE BY HOMOLOGY BIO13.04 TRANSPORT AND BINDING
                     proteinS. Carbohydrates, organic alcohols and acids. gene
                     contains a frameshift mutation at position 453."
     gene            complement(11461..12195)
                     /gene="yugA"
                     /locus_tag="L47971"
     CDS             complement(11461..12195)
                     /gene="yugA"
                     /locus_tag="L47971"
                     /note="EVIDENCE BY HOMOLOGY BIO09.01 REGULATORY FUNCTIONS.
                     General. There are eight paralogs in L.lactis. Belongs to
                     RpiR family of transcription regulators."
                     /codon_start=1
                     /transl_table=11
                     /product="DBD-Pfam|HTH_6"
                     /protein_id="AAK06083.1"
                     /translation="MSNLTNAESYTWQIIQENYEKIPQLSISELAELAHVSLSTVNRTV
                     RKKGFEGYGEFRYSIREKKLPEINGFSKEVLGAIAKNQEELLKTIENISAEEIEKAVEL
                     IQESEEILIFSRGLSTNVADELMKKLQLFRKPVSLHDDSKYMAYYARFVNEKSLIIVLS
                     LSGETVEILNALNIAKGQNPKILSLTVNANTSLTNLSDISLIGYKSSLEVNYFDLDVHS
                     RLSLSILSRVLIDAYSIYTLKQ"
     gene            12324..13187
                     /gene="yugB"
                     /locus_tag="L48789"
     CDS             12324..13187
                     /gene="yugB"
                     /locus_tag="L48789"
                     /note="EVIDENCE BY HOMOLOGY BIO06.01 ENERGY METABOLISM.
                     Aerobic. There are six paralogs in L.lactis"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|P77735|8.A.5.1.6"
                     /protein_id="AAK06084.1"
                     /translation="MTYIPNPTRYDHMIYRPAGNSGLLLPALSLGLWHNFGSVDDFENA
                     RDMIHTAFDLGITHFDLANNYGPEPGSAERNFGRILKEDFQKLRDELIISTKAGYPMWP
                     GPYGNWGSKKSLLASLDQSLERLGLDYVDIFYSHRPDPNTPIEETMGALKSALDSGKAL
                     YVGLSNYSAKETEAAVLAAEKLGFKLLIHQPRYSMLDRWIEDDLQETLTEAGIGIIAFK
                     PLYQGLLTEKYLHGIPEDSRMRDPHYATLHDDSLTKKRLEQVQALNDLAQSRGQSLAQM
                     ALAWVL"
ORIGIN
        1 ttatggtgtt tcatataaaa aatttttaac atattttgct acagttggat ttgtcggagc
       61 ttttgaatgc ctaagtttcg ttggatacaa acttgcaatg atttcatttc cattcttttt
      121 aaaaagatgg taaattgaaa aactatctgc ccacggaata gcactatccg tctgtttttc
      181 cgtatcaaaa tctccttcta acaacatcat ttttgttttt ggtgatatct ttttatagtt
      241 atcagcaata taattataca ttgtagtttt aattaaaggg ccatttttca acacatccgt
      301 caaagtttct cctgcaacaa gatttgttac atcattatat tccccttcta aagaaaaata
      361 tttattgacc ggaggaaaat tagatttatc tgccgtatca atcatgtaat agattgctcc
      421 agttgcacca gaagaataac caactaaatt aatccatggt acttgataat gctccaccag
      481 ataactaatt gctttttgta atcctttgga aaaaagagag cccgaatccg ttttggcaac
      541 cgttccaaat tcaatcattg gatactgcat atctttagaa atatttcctt caacttttaa
      601 ttcatagtct ttctgaacat ctgacatgag aaccaatggt ttatcccccg ctttttccat
      661 tggtaaaagt tgagtaacta accgattaat tgacgatacg tcccctccag aacctgtaat
      721 ataaattgtt ggataaatca cttgttttcc tgaatttgat atggagctac tactagtttt
      781 tgtcgatatt gatgacgttt gtttatcatt atttttggtc acggaggtta tccctttagg
      841 ccaaaaaaga aaaagagctc ccgctaaaat aatcactaaa ccaaaaaaag ctagtgatac
      901 tcttttaaat ttatttttat ttcttcttaa ctgtcttttt ttcatccact ttattatatc
      961 aattttttta ataataatta tcacaattac cattacattt tcatgacgat tacatacaaa
     1021 aaaagctcaa aaatttgagc tttttttttc gaattttaga taattaacta gtaacctttt
     1081 ggatgacttt ggtgccattt ccaagcgttc gtaataatgt gctctaaatc attttgtgct
     1141 ttccaaccca aaatttcacc agcttttgtt gaatcagcaa ccagctcatc tgggtctcct
     1201 gcacggcgtt cacccatttg gcttggaatt tctttacctg ttacttttcg tgcggtttca
     1261 agcacttcaa gatttgaata acccttactt gaaccgagat taaattggtc agactgaccg
     1321 cccgctttaa gatactctag tgctttgatg tgtgcttcaa tcaaatcttc catatcaata
     1381 taatcacgaa tacaagttcc atcaggcgtg tgatagtcat caccataaat agtaatgaac
     1441 tctctttgac caagtgcagt ttgcaaaata attggaatca aatgtgtttc atttttatga
     1501 gcttcaccaa ttgaaccatc atccttagcc cctgcaacat tgaaataacg taaagcgaca
     1561 taagtcatat cagttgcttg cgattgccat ttcatcattt tttccatgat taatttgctt
     1621 tcaccataag gattaattgg tttttgaggt gttttttctg aaattggact tttttctgga
     1681 attccaaatg tagctgctgt acttgaaaaa acaatatgtt ttactccgaa ttcttccatc
     1741 gtttctagaa ttacttgagc accaccaaca ttattattaa aatacattaa aggtttttgc
     1801 attgactcac ccactaaaga gtaagcacaa aagtgcatga ttccttcaat attttctttt
     1861 tcaaaaacat ctgctaagaa agcttgatca cgtacatcac cctcgtaaaa gcgtacattt
     1921 gctggaacag attcacggtg gcctgtcact aaattatcca ccactgccac atcgtaacca
     1981 cgtttaagaa gcatatctac cgcgtgactt cccacgtatc ctgctccacc aagaactaaa
     2041 accgtcataa gaacctccat tttctctata ttatatcaaa ttcttgaaaa tttggatcat
     2101 cacgttaatt taaaactaac ttcataatga taatttccct ttgtcaataa atattcctga
     2161 gcgacacttg gactccatga atcatctcca cctacaccca tatggaatcc gtcaatattt
     2221 aaccatgttc ctgcttcttc ttcaagtaga tgccaatgtc cctttttagc aagctggttt
     2281 tgactatacg gacttagatt aaaagcaaaa gattgaccca ttgcccgaac ttttaaacga
     2341 tcataattta actctctggt ttccatcctc aacccatttt cactaggaaa aatataaggg
     2401 gttgtcatat cagtaatcct taaattccac tggccaaata aacttgcccc tcttcggtca
     2461 ggataatttt catctgggcc aagtccaaaa tatgtaacat tttctgcttt ttcagctagt
     2521 tgaagactca agccaattcg agctggttct ggaaactcta tatttctttt aaaatcaact
     2581 tttaaaagaa gttcaccgtt tctaaaaata tgatattctc gaatggttga aaatgcaatt
     2641 tttccttttg cttcatagtc tgtttggaca gaaataatta cttcattctc tgttgcttgt
     2701 attatcatag ttttcaaaag cgtttttaac tcataaaagc caataccctt ccaacgttct
     2761 aaccaagcat taggatcaat atgttcaact tcactaacac caatatcatt atctaatgga
     2821 gcccttgtaa attgttctga gagctcatgc agtaactttt cattgccttt ctcatcaagc
     2881 cagcgcgaga gattaccatt gcttttatta aaaataaatt tctgttttgc tgatcgtacg
     2941 gtcagtagct cttcatcctc aaaaagtgta atttcttcat tactatctat tctgtcagta
     3001 aaattaattt tttcttgtag aacaaattgt tgatgagcaa cttcaaaatc agactcaaga
     3061 agattacatt tctcaattgt tttaacttga atgttcaaaa ataaattatc tgttccatca
     3121 ataggcaact cagacaggtc tattctcata gaccctccag caggcatatt caatataagc
     3181 tcattttccc ataatacttc taagccattg atcagttggt aacataattt ttcattgtca
     3241 gtacttcgaa atagatactc atttgtaact gtaaaggcaa aaacttgacc tagtggagtt
     3301 ttctccaatt caaactgata atattgttgc caatattttg cttcacgaag agctggtttt
     3361 gcttgacgat ttggaaaaac aagaccatta aggctaaact gacgatcatt tggcttgtcc
     3421 ccaaagtcac ctccataagc ataatttcca tcttttaata aaccttgatc cacccaatcc
     3481 cagatgaatc caccttgcaa tcggtcaatt tctcgaaaag cttgccagta cttcccaaat
     3541 cctcctaatg aattccccat atcatgagca tattcacaaa gaattagtgg tctattctct
     3601 ccagctaccc ccatccaggt ttttaatgaa taaggcgcat taatacttgg actatctact
     3661 ctagcataca tcggacaaat gatatcagtg gcatctgttg ctcctctact tgcgtcatct
     3721 cccccctcat aatgaacagg gcggctagaa tcaaatgatt tacaccaatc atataaagct
     3781 tgatggttac ttccataacc tgactcattc ccaagagacc aaataataat tgatggatga
     3841 ttacggtcac gcataaccat tcgtgtaaca cgttcactca ttaatggtaa ataagtcgga
     3901 tcatttgtca aacgattcat cggagtcatt ccatgcgttt cgatatttgc ttcatccata
     3961 acatacaatc catattcatc acacaattca taccagcgtg aatcattagg ataatgagag
     4021 cagcggaccg cattaaaatt atgttctttc atcaatttga tgtctttaat catcacttct
     4081 tcagaaacga cataaccatg ctcaggggta aattcgtgct tattcactcc acgaacaaga
     4141 agtgctttcc cgtttatttt tagctgtcct ttttcaatag caatttttcg aataccaatt
     4201 ttttttgttt ctttatgaaa taccgcccca ctccggtcca ttaaagttaa ttctaaacga
     4261 taaagatagg gaatttcatc tgaccataat tttggattga ctactccaat ttctgcatca
     4321 aaaccatgac actctccaat taattgttcg tcatcataaa gcttaaattc taaacaagca
     4381 tcatcgatgt ttttagcata tgcttgaagt tttacatttg caaaatctaa atcctcatcc
     4441 aaatctgttt ttatagaaaa gtctaacaag tagttatctg gaagccattg taagttcacc
     4501 gaacgaaaaa tacctgacat tcgccacata tcttgatctt caaaataggt gacttttgac
     4561 caacgaaaaa ctagaacttt taaacaattt tgaccttctt tggccaggtt gctgatatcg
     4621 aattcagcag gcaagcggct atcttctgaa taacctccgt attccccatt caaccaaaaa
     4681 tgaaaagctg atccaacccc ttcaaatgta aggtgaacat gaccgctctc aagccattct
     4741 tttgtgatat caaaatagcg actataagct ccaactgggt tagcctctgg tacataagga
     4801 ggctgaattg gaataggata agtcacattt gtataaattg gaacatcgct tttatcctta
     4861 aattctattt gccaattact tggaacgata atttccgttt tactctccgt cagttctaac
     4921 caatttttag gtacatctga aattctagaa aaatgatcaa aattccaaag accattcagt
     4981 gattgctttt ctaacaagtc cataggtgta tgcattggca acctattcca atttgaaact
     5041 actggatttt cccaatcttt acgctctagt acatcaatca ttgtcatcat agccattcct
     5101 ttcagatgaa ctcatctaaa tcaatctttt ttccatgatc ataagtttta aagtcagaat
     5161 cattaatttt tcttttaacc atacaaggag ttccaaaagc aaccacatta tctggaatgt
     5221 ctttagttac aagactccct gcgccaatca cactattttt tccaattcta acaccaggta
     5281 aaacaattac accagcacct agccaaacgt tttcttcaat gtaaactttt ttattatatt
     5341 gagcccctcg tttacgtaag tcaggcgaga caggatgtgt cgccgtgtca atcgtaacat
     5401 ttggtccaaa catgacatga tttcctacaa aaatatctgt atcgtcaacc aatgttagat
     5461 taaaattagc ataaatctct gtcccaaaat gaacattttt tccgccaaaa ttagcataaa
     5521 aagggggttg aataaaacaa ttttccccaa tttctgaaaa cattttttta gaagttccat
     5581 ttgttgctct ggctgagtca ctgaagtttg attaaacttt tccagtaaaa ctaaagcttc
     5641 ttgttgctct ttccataatt tttgatcgtt aggaaagtag agttcttctg tgtgaactcg
     5701 tttgtagctt tctaatttag gcattttatc aactcctttt taaagctctc ttgatttatg
     5761 aaaattaatt atttacgaaa tttataaatt cataaaaacc tttttgtcct acttcattat
     5821 ctttgaatac tccggcatct tttaacacct gttcaaatac ttctccaact gcttcctgaa
     5881 ctgtttcatg aactgtttct tttgaaaaat attctgtttc tttcaattct tcagcccatg
     5941 gtttgtgaat ttctgacatc tcattttctt gattcaagag atatttttca acttccaaaa
     6001 gttctgtctt taacctggct ggtaaaattg caagtcccat cacttcaatc aatccaatat
     6061 tttctttttt aatatggtgt aaggctggat gtggatgaaa aattccatct ggataaattt
     6121 cacttgtatt attatctcgt aaaactaaat ctaattcata tttcccctct cgaattcgag
     6181 caatcggagt aattgtatga tgaagctttc cgtcagcact tttagctttg atttgaagac
     6241 tttcatcact ataaacttgc cattttttta aaagttcatc tgcagctttt gaaagttcta
     6301 cttggttttt acttgataat cttagaacag acattggcca attcacaatt ccgcaagaaa
     6361 cttctggaaa ttgttgaagt ttaatttctt ctcgaagttc agcttttgcc atcggaaatt
     6421 cataacgtcc agcttgataa tggtcatgag tcaaaattga ccctcctaca attggtaaat
     6481 ctgcattaga accaatcata taatcaggaa attgatctag aaatcccaat aaattatcaa
     6541 aagcacgttt attaatttcc attggttggt gtttagcatt tagtaaaatc gagtgttcat
     6601 taaaataggc ataaggagaa tattggaagc cccagtcttc gccgttaatt gagacttgaa
     6661 tgattcgatg attagaacga gcaggtttat ttcctatgcc ataaaatcct tcgttttcca
     6721 aacaaagttg acaggctgga taagaggaag cctttactaa tttagctgcc gcaatggctt
     6781 tggggtcttt ttctggtttt gagagattaa tcgttatttc aagttttcca tattttgtca
     6841 aatgactaaa ggcaatatta cgtgtaatat ctcgagtttt tacttggttc acttgctgtg
     6901 ccagttcata aaaatattga gttgctgcat ctggagaagt cttatatttt tcccagaaat
     6961 cttgattgat tttacttggg cgtggtgtaa taaaattcat cagagcggct tcataaaatt
     7021 catcttgtcc tttttcaatc acattatttt catttgcaat cgctaaaagt tggtccatta
     7081 aaatcaagga atctttctcg tgagcttctt tatcgacttc tgcccaatca tttagaccaa
     7141 gaaaatgaag aagttgattt ctgtgataga gctcatcaag tggctcaatc gttccatttt
     7201 gtaaagcaag actaataaaa tcttgaattg attgataaat tgacataaaa tactttctaa
     7261 tttacttctg taagtaaagt tcttgctttg tcttgattag tgagttttgg aaatgaatac
     7321 aaaattcaag cacttagttt tgagtgcttg aatttgctat cactaattta atgttaactc
     7381 acttaaatca ctcataaaat tttttaaata ttatttgatt tattcaacat ccaactttgt
     7441 tgaaccagaa ccaatttgag cgacgtaaaa gcttgctgga taaccgacaa cttcttcgta
     7501 aacttggccg acggcttttt caaaggctga aacattgtca tgagcaacaa gagcgattgc
     7561 acaaccgcca aatccggctc cagtcattct ggcccccaag acaccggctt gtttttgagc
     7621 agtctctgct aaggtatcaa gttcaagtcc tgtgacttca taatcatctt tcaaagaagc
     7681 atgtgaagca ttaagaagtt ctccaaattt tgtcaaatta cctgcaacaa atgctttttg
     7741 agcaatttta gttcgattat tttcataaac ggcatgacgt gcacgtttaa ttaatgtttc
     7801 atccccaatc aaatcagtat tggcatcaaa ttcttcattt gataattctc caagtgattg
     7861 aatgtccaat ctcgtttgca ttcttttgag cgcctcacgt gtttcagcaa aacgttcgtt
     7921 gtattttgat tctgtcaaag cccgcggttt gttagtattc atgataacaa tatcataatc
     7981 acgaagttca acaggaacca tctcatattt tagagtgtta cagtccaata ggattgcttt
     8041 tttgacttca ccaaaaccaa tagcgaattg gtctaaaatt ccagaattaa caccaatata
     8101 atcattttct gttttttgtc ctaattgaac caattcaaga cgtggaacat ttaagttaaa
     8161 taaatcatcc aaaacaacgc cgactaaaag ctcaagtgat gctgatgatg aaaggccaga
     8221 tgctgtagga atttctcctt ttatcaacaa ttcaaaacct ttgtcaattt catatcctgc
     8281 tcctttaagc atgacaatca ttcctttaac ataattagac caaagctcac catctttctt
     8341 ttcaacttca tctaaatcaa attcaatgac gcctaattta ggaaaatttt ctgagtaaag
     8401 tttgactttt ttatcttctc tcagacgagc tagtcctgtt gttccaattg taattgatgc
     8461 tgggaaaaca tatcccccat tgtaatcggt atgttcacca atcaaattaa ttcgtcctgg
     8521 gctaaaaaag tattcaactt cttttgtatc tccaaaaact tctgcaaatt tttctgttaa
     8581 tgctgataat acagtactat tttctacaac tatagacatt tcttctctcc tctaaattta
     8641 tttctttatt ttgtatgcaa gctgtaaatt gtggttgctt gatatttttc tcccgctttt
     8701 aggctgatat ctccaagctc tggaatttgc tcagacccag gtgatacttg acattcaaaa
     8761 gtaattccac catggtgcac ttgctttttc tcatgataaa gagttcctaa atcaccaaaa
     8821 tttgctgtaa atatcacaat acttggttgg tcggtaaaga ctgaaattga agtatcatca
     8881 agcgttaaac gagcttgttc tttatcaagt cctaactggt ctaacaagaa aggatggtca
     8941 attcctttaa ctaattgaac ttgttccata ttagaattga aggcatttga taattgtttt
     9001 tcctgacgga aatccaagtc tgtatttttt atatcaacga tatcaccacg aacaatttct
     9061 gtttggtctt ttaaaggaac aaatcttgaa gcggccagtc gaagtccatg attttcaaca
     9121 gattcactag catcaccatt caaattaaaa tagacatgcc cagttggatt aaacacagtg
     9181 tctttatcag aaatggcctc ataatgaatt ttccacttat tgtcatcatc aaaagaatga
     9241 gttactgaca tttctatttt accaggataa ccatttgttc cgtcattaga aactaaggaa
     9301 aatttgactt gaacttcagc tcctaaatcg gtaacttcat atgtccaaag tttagtatga
     9361 atactttctt ccccaccatg taaggtttga gggccttcat tttgatttaa gatataatct
     9421 ttcccagaaa ttttgaccaa accatcctta attcttcctg ctgtaggtcc aacagttgca
     9481 ccaggatagg catctttttc taaatattct ttagctgaat caaagcctag aatcagatgc
     9541 tttccatctt tttgccagtc aacaatccga gcgcccagat ttgtaaaaga aattgtgaca
     9601 cctgctttat tggttagact aattaagtca cttcctaagc caaaatctct tattttaatt
     9661 tccatgatat ttcctaacta taatgacctt taatcaaatt ttaaaaattc tactgacaga
     9721 tttactgatg acagtttaaa caaatttcat ctttttattt tctatcttac aaaagctgtc
     9781 agtaaattat ttacctattt taaacgttct tcgagttctg caacaatttc ttcgtgacgt
     9841 ttttcagtca atttaacttt gaataaataa actgctaaag cgataatcat caaaatggct
     9901 ggaactacaa atgagtagag tttaaatgtt gccacaccgt aagtgtgtcc agcgatatat
     9961 tttgaacctg tcattccggc tgaaattgcc acaaatccat agataccatt tgagaaagcg
    10021 ccggcaattt tatcaagcaa tggacgcatg gcaagcgtta cggcttcatt acgtactcca
    10081 tttttccatt gaccatattc taccgagtca gtaattgtca ttaatactga caagaaaaca
    10141 agttgatagg gggcagttaa gaagattaat ccagcaacag tcattgctac tgaacttcct
    10201 aaaacgaaca agagataacc aagaagcatt gaaatgattg ctccagtcaa aactttgcgt
    10261 cgtccaaatt ttttagctaa aatcggaaac attgggacga gaatgattga accaatgaat
    10321 ccgacaattc ctgtaattga ataaagacta gcatttccaa taacaaaagt aaagttcaaa
    10381 atcaaagttg ctgttgttgc cacataagca atggcaaata aaatatatga aagtgacaac
    10441 cacattaatt ggtcgttttt taggagcgct ttaaatacat ccaatgtatt tgttttggtt
    10501 ccttcttgac gaataactga tttttgttct ttagttcccc aagcggttac caaagccgaa
    10561 attccttgga ccaaagcggc aataacacca aaagcaaaga atcctcttgc tccttgagca
    10621 tgtccacctt tagtaaagaa aattgtgatt ggaatcgcta aaatagttgc cccttgcgca
    10681 ccaattgctg agccaaaacg ggcgaaagtt ccaagtgttt cacgttcaga attttttctg
    10741 atagcgctgg aatcattgac cagaaggcaa tgtctttgaa tgaataaaag gcgtcaagaa
    10801 taataaaggc aatgatgaag acaatggcaa ataatgtacg attatcactt tttgctagtc
    10861 cgaagaagtc tgaaaacatg agcataatca tcaaagatga cataatccca ccaacaacca
    10921 accaaggttt aaattttccc catcttgtgt gggtattatc aataattgaa ccaatgattg
    10981 ggtcaaaaat aatttcgatt aaacgaataa taacgactaa actagtgact aaagcaatca
    11041 tcgcatcctc atgtggtgtt ccagcaaaca tttgtgccgt tacaaaggcg atgaagaatg
    11101 tactaattga ataatagtaa acatcatgtc ctaatgcacc aaaagcgtac gataaacgtt
    11161 gtttcatttt tccctctttc atgggaatcc tcctttatac taaatctact taattcataa
    11221 gtaaatctac aaagctactg ttttgccttt tgaaacgagt aatccttggt tgggaaaact
    11281 tttattttgg ataagttttt aaaagcgaaa cagtcttcaa tttcattttg aaatcgctca
    11341 catttagagt ataacacttt gatttaagaa agggtttcca attttagctt atcttttgga
    11401 aaccctttct attttgctct ttttataaaa aaaagctcga tatgacttga tatcgaagca
    11461 ttattgtttt aaagtataaa tggagtaagc atcaattaga actcttgata aaatggataa
    11521 tgagagtcta ctatgaacat ctaaatcaaa ataattcacc tcaagactac tcttgtaacc
    11581 aatcaaactt atatccgaaa gattggtcag actggtatta gcattaacag ttaaggataa
    11641 tattttggga ttttgtcctt tggcaatatt tagagcattt aaaatttcta ctgtttctcc
    11701 tgaaagtgat aaaacgatga ttaggctttt ttcattaaca aaacgggcat agtaagccat
    11761 gtattttgaa tcatcatgca aactgacggg cttacggaaa agttgcaact ttttcatcag
    11821 ttcgtcagca acgtttgttg ataagcctcg tgaaaaaatt aagatttcct ctgattcttg
    11881 aatcaactcc acagcttttt caatttcttc agcagagata ttttctattg ttttcaaaag
    11941 ttcttcttga tttttagcaa tagcccccaa gacttctttg gaaaaaccat tgatttcagg
    12001 aagttttttc tcacgaattg aatatctaaa ttcaccataa ccttcaaaac ctttttttct
    12061 tactgttcga ttgacagttg agagagaaac atgagccaat tctgccaatt ctgaaattga
    12121 taattgtgga attttctcat agttttcttg aataatttgc caagtatagg attcagcatt
    12181 ggttaaattg gacatatttt tactccattg attcgcttgt tgttatcaaa aaatgttttc
    12241 tatcctaaaa ttataacatt tgacgcttac atttgctata attccctgaa atcgttttta
    12301 tttctatttt taaggagaaa gtaatgactt atattcccaa tcccactcgt tatgaccaca
    12361 tgatttatcg cccagctgga aattctggtt tattattgcc tgccctttca ttaggactct
    12421 ggcataattt tggttcggta gatgattttg aaaatgcgag ggacatgatt catacggcat
    12481 ttgatttagg aattactcat tttgatttgg ccaataatta tgggccagaa cctggttcgg
    12541 cagaacgtaa ttttggtcgt attttgaaag aagatttcca aaaactacgt gatgagttaa
    12601 ttatctcaac taaagctggt tatccaatgt ggcctggacc ctatggaaac tggggcagca
    12661 aaaaaagttt gctggctagt cttgatcaat ctttggagcg tttgggactt gactatgttg
    12721 atatttttta ttcacatcgt cctgacccaa atacaccgat tgaagaaaca atgggggctt
    12781 taaagagcgc tctggatagc ggaaaagcac tttatgtagg tttgtccaat tattccgcca
    12841 aagaaaccga agctgcggtc ttagcagctg aaaagttagg ctttaaactc ttgattcatc
    12901 aacctcgtta ttcaatgcta gatcgatgga ttgaagatga tttgcaagaa actttgacgg
    12961 aggcggggat aggaataatc gcctttaaac ctttgtacca agggctctta accgaaaaat
    13021 atttacatgg tattcctgaa gattcgcgaa tgcgtgatcc tcattatgca actttgcatg
    13081 atgacagtct tacgaaaaaa agattggaac aagtccaagc gcttaatgat ttggctcaaa
    13141 gtcgtggaca atctttagct caaatggcct tggcctgggt tttatga
//
