LOCUS       FP476056               15876 bp    DNA     linear   BCT 27-MAR-2015
DEFINITION  Zobellia galactanivorans strain DsiJT chromosome, complete genome.
ACCESSION   FP476056
VERSION     FP476056.1
DBLINK      BioProject: PRJEB8976
            BioSample: SAMEA3315864
KEYWORDS    .
SOURCE      Zobellia galactanivorans
  ORGANISM  Zobellia galactanivorans
            Bacteria; Bacteroidetes; Flavobacteriia; Flavobacteriales;
            Flavobacteriaceae; Zobellia.
REFERENCE   1
  AUTHORS   Thomas,F., Barbeyron,T., Tonon,T., Genicot,S., Czjzek,M. and
            Michel,G.
  TITLE     Characterization of the first alginolytic operons in a marine
            bacterium: from their emergence in marine Flavobacteriia to their
            independent transfers to marine Proteobacteria and human gut
            Bacteroides
  JOURNAL   Environ. Microbiol. 14 (9), 2379-2394 (2012)
   PUBMED   22513138
REFERENCE   2  (bases 1 to 15876)
  AUTHORS   Genoscope -,C.E.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-JUL-2009) Genoscope - Centre National de Sequencage :
            BP 191 91006 EVRY cedex - FRANCE (E-mail : seqref@genoscope.cns.fr -
            Web : www.genoscope.cns.fr)
FEATURES             Location/Qualifiers
     source          1..15876
                     /organism="Zobellia galactanivorans"
                     /mol_type="genomic DNA"
                     /strain="DsiJT"
                     /db_xref="taxon:63186"
     gene            complement(1..1227)
                     /gene="pfp"
                     /locus_tag="ZOBELLIA_2613"
     CDS             complement(1..1227)
                     /gene="pfp"
                     /locus_tag="ZOBELLIA_2613"
                     /EC_number="2.7.1.90"
                     /function="Diphosphate + D-fructose 6-phosphate = phosphate
                     + D-fructose 1,6-bisphosphate"
                     /note="Diphosphate-fructose-6-phosphate
                     1-phosphotransferase catalyzes the reversible
                     phosphorylation of fructose-6-phosphate using pyrophoshate
                     instead of ATP for phosphofructokinase (Pfk). Involved in
                     glycolysis. It forms a homotetramer. Localized in the
                     cytoplasm.; High confidence in function and specificity"
                     /codon_start=1
                     /transl_table=11
                     /product="Diphosphate-fructose-6-phosphate
                     1-phosphotransferase"
                     /protein_id="CAZ96763.1"
                     /db_xref="GOA:G0L677"
                     /db_xref="InterPro:IPR000023"
                     /db_xref="InterPro:IPR011403"
                     /db_xref="InterPro:IPR022953"
                     /db_xref="UniProtKB/TrEMBL:G0L677"
                     /translation="MASKKSILIICGGGPAPGINAVISTVAKIFLKDGYRVLGLHEGFK
                     GIFSEEPQIKEFDFAHADRIFSRGGSTLIMSRFKPSDEKINTKLFSDNNVKLLVSIGGD
                     DTASTANRITGYLLKENISISNIHVPKTIDNDLPLPDRNPTFGFHSAKDEGVRIGNTTY
                     EDARTSQNWFVMSTMGRSAGHLAFGIAASCHFPMMVIPEMFNQTPITFDKVVRLIISSI
                     VKRKIKNINYGVALVSEGVFHIMPDSELDHCGINFTYDDHGHPELGNVSKSHIFNMLVQ
                     VKLKELGIHIKSRPVELGYELRCCRPIGFDLTLCTLLGIGVKKLFDQGLSGCIVTANSR
                     GEVTPLFLEDLQGEDGKIAPRLVEVDSEFARLFFQNMHYIEESDYEAAKAYLPDPESYD
                     FNKILSGEV"
     gene            complement(1246..2286)
                     /gene="kdgK1"
                     /locus_tag="ZOBELLIA_2614"
     CDS             complement(1246..2286)
                     /gene="kdgK1"
                     /locus_tag="ZOBELLIA_2614"
                     /EC_number="2.7.1.45"
                     /function="Carbohydrate metabolism:
                     2-dehydro-3-deoxygluconokinase activity"
                     /note="The 2-keto-3-deoxygluconate kinase (KdgK)
                     phosphorylates 2-keto-3-deoxygluconate (KDG) to form
                     2-keto-3-deoxy-6-phosphogluconate (KDGP) in the
                     Entner-Doudoroff pathway. KDG is the common intermediate
                     product, that allows organisms to channel D-glucuronate
                     and/or D-galacturinate into the glycolysis and therefore
                     use polymers, like pectin and xylan as carbon sources;
                     Belongs to the Carbohydrate kinase, PfkB family,
                     2-dehydro-3-deoxygluconokinase (KdgK) subfamily; Localized
                     in the cytoplasm; High confidence in function and
                     specificity"
                     /codon_start=1
                     /transl_table=11
                     /product="STP|PfkB"
                     /protein_id="CAZ96764.1"
                     /db_xref="GOA:G0LC99"
                     /db_xref="InterPro:IPR011611"
                     /db_xref="InterPro:IPR029056"
                     /db_xref="UniProtKB/TrEMBL:G0LC99"
                     /translation="MKKVVTFGEIMLRLAPPGFLRFSQANSFDVVYGGGESNVAVSLAN
                     YGVPVDFVTRLPKNDIGECALMEMRKRGVNTQNIIFGGDRLGIYFLETGAVSRGSKVVY
                     DRAHSAISEIEPGMIDWKKVFEGAGWFHWTGITPAISQSAADVCLEAVKVASDMGITIS
                     TDLNYRAKLWNYGGDREAIMTELTSYCDIILGNEEDAEKHFGIHPEGLDVHKQGSEVKA
                     EAFLSVCKQMMKKFPKAKKVITTLRGSISASHNTWAGVLYDGKKMYETRQYQITDIVDR
                     VGGGDSFMGGLIYGLLQYPEDDQNALDFAVAASCLKHTIKGDANLVTVSEVEKLMGGDA
                     SGRVAR"
     gene            complement(2341..3096)
                     /locus_tag="ZOBELLIA_2615"
     CDS             complement(2341..3096)
                     /locus_tag="ZOBELLIA_2615"
                     /EC_number="1.-.-.-"
                     /function="Oxidoreductase activity"
                     /note="The enzymes of this family are very similar and
                     display high sequence identities, the substrate specificity
                     is difficult to determine; A match to Glucose/ribitol
                     dehydrogenase subfamily indicates that the protein is not
                     an alcohol dehydrogenase, but another type of dehydrogenase
                     or reductase; Possible signal peptide cleaved between the
                     residues 20 and 21; Putatively localized in the periplasmic
                     space; Family membership"
                     /codon_start=1
                     /transl_table=11
                     /product="Acetoin(diacetyl) reductase"
                     /protein_id="CAZ96765.1"
                     /db_xref="GOA:G0L678"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR020904"
                     /db_xref="UniProtKB/TrEMBL:G0L678"
                     /translation="MKRKVAVITGATGGIGFAVAKRLGQDGYTVILNGIDDEAGAERVK
                     ELTSEGIEAEYYSFDVTNEEAVTKNIKAIGEKYGKIDTLVNNAGGLGGRSRFEEMTTEF
                     YRSVMALNLDSTFFASRAAIPYLKKGEGASIINYTSNAAWTAGGPGAGIYGTSKAGVNT
                     ITKALAKDLAEYGIRVNAVSPGTIDTPFHAQIKATKPEVFASWANSIMLGRLGQPEDVA
                     GVVSFLASSDAKFITAETIQIGGGQALGI"
     gene            complement(3133..4410)
                     /locus_tag="ZOBELLIA_2616"
     CDS             complement(3133..4410)
                     /locus_tag="ZOBELLIA_2616"
                     /function="Permease activity"
                     /note="The Sugar permeases belong to the major facilitator
                     superfamily (MFS) transporters that are single-polypeptide
                     secondary carriers capable only of transporting small
                     solutes (probably sugars in this case) in response to
                     chemiosmotic ion gradients; Contains 11 transmembrane
                     segments; Localized in the cytoplasmic membrane; Family
                     membership"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q07YH1|2.A.1.14.25"
                     /protein_id="CAZ96766.1"
                     /db_xref="GOA:G0L679"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR020846"
                     /db_xref="UniProtKB/TrEMBL:G0L679"
                     /translation="MKVKGLRWWVIALICLATVINYIDRTAFGVMWPEMGKDLGMDESD
                     YAIMLNVFMITYAAGKFLSGKLYDIIGTRMGFVVSIVVWSVASIFHAFARGLVSLTLFR
                     AMLGLGEAGNWPGAVKSNGEWFPVKQRAIAQGIFNAGASLGSVIAPVLIAYLYGHFGWR
                     TTFIIIGAIGLLWVIPWLVINKAKPENHPWITEEEQKIILADQIAFSSPEKKEKGLSVL
                     KILSYKESWGVLMSRFFIEPIWWLFVGWMPLYLNSKFGFSIEEIGSTIWISYLGGMAGS
                     IVGGWYSGKLMETKTVDAARKITITIGGALIFLGLLGIIFLVTEKNPMTFIYIVAVVLF
                     GFQFAIGNIQTISSDLFRGPSVGTLAGLAGTVAAVSVIIMNSLIPMIASVSYTPAFIVI
                     AVLAPLAVLSIYGLIKRIRPVELESV"
     gene            complement(4641..5369)
                     /locus_tag="ZOBELLIA_2617"
     CDS             complement(4641..5369)
                     /locus_tag="ZOBELLIA_2617"
                     /function="Transcription regulator activity"
                     /note="Transcriptional regulator involved in the repression
                     and/or the positive regulation of genes encoding for
                     enzymes; Contains an N-terminal HTH domain of GntR-like
                     bacterial transcriptional regulators, involved in the
                     binding of the protein to the operator sequences in the DNA
                     and a C-terminal FCD domain that probably binds to a range
                     of effector molecules that regulate the transcription of
                     genes through the action of the N- terminal DNA-binding
                     domain (HTH domain); Localized in the cytoplasm; Family
                     membership"
                     /codon_start=1
                     /transl_table=11
                     /product="DBD-Pfam|GntR,DBD-SUPERFAMILY|0039384"
                     /protein_id="CAZ96767.1"
                     /db_xref="GOA:G0LCA0"
                     /db_xref="InterPro:IPR000524"
                     /db_xref="InterPro:IPR008920"
                     /db_xref="InterPro:IPR011711"
                     /db_xref="InterPro:IPR011991"
                     /db_xref="UniProtKB/TrEMBL:G0LCA0"
                     /translation="MKLEILTKHENRDIQNGIIAKIRDLINYKNLEPGDKLPAERVLSE
                     KFGVSRSNVREAIQKLEFYGILNSKPQSGTFIANIGQIAMNGMIDDILSLEEQDFKSLV
                     ETRILLELKTVKLAALRRTEEDLERLKQAFNAYKTKMIAGDDCLEEDLLFHLAIASASK
                     NSTMNTLMLLITPEIIVAYDQDRVCDGDVALAEVKKHEDIYMAIKDQNPQLAKEKMKLH
                     FSKLYDYIYGKDRKIKIGKG"
     gene            complement(5611..6534)
                     /gene="alyA2"
                     /locus_tag="ZOBELLIA_2618"
     CDS             complement(5611..6534)
                     /gene="alyA2"
                     /locus_tag="ZOBELLIA_2618"
                     /EC_number="4.2.2.3"
                     /function="Eliminative cleavage of polysaccharides
                     containing beta-D-mannuronate residues to give
                     oligosaccharides with
                     4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at
                     their ends"
                     /note="Alginate lyase catalyzes the eliminative cleavage of
                     polysaccharides containing beta-D-mannuronate residues to
                     give oligosaccharides with
                     4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at
                     their ends. It belongs to the family 7 of the
                     polysaccharide lyases. Features a signal peptide cleaved
                     between residues 32 and 33. Localized in the periplasm.;
                     High confidence in function and specificity"
                     /codon_start=1
                     /transl_table=11
                     /product="PL7"
                     /protein_id="CAZ96768.1"
                     /db_xref="GOA:G0L680"
                     /db_xref="InterPro:IPR013320"
                     /db_xref="InterPro:IPR014895"
                     /db_xref="UniProtKB/TrEMBL:G0L680"
                     /translation="MQFLSNFFRACYLSLVLVSAGNCQDSNDLAVAANHQDGPYANSDT
                     PETESVDIKKYKLPKIDLSHWKLTLPVGKPTEVEPPEILEYATNEVVRPYFYNDSTDGS
                     LVFYAFPNSTTANTKYSRSELREQMVPGDNNVNWTFEQGGRMKGTLAVDEITKDSDGKY
                     HRTIIMQIHGRLTNEQKELIGAKDNNAPPILKIYWDKGYVRVKTKVLKNKSASDQEILH
                     EEAWGDDEGYTFPDYVGFKKFKLEVKVSKGKLVVIMNNTEYAVYDDVNIKRWGIFENYF
                     KAGNYFQSKDEGSYAKVKFYDLEVIH"
     gene            complement(6543..7424)
                     /locus_tag="ZOBELLIA_2619"
     CDS             complement(6543..7424)
                     /locus_tag="ZOBELLIA_2619"
                     /note="Contains a N-terminal PKD domain present in the
                     extracellular parts of proteins involved in interactions
                     with other protein or polysaccharides and a C-terminal
                     putative carbohydrate binding module (CBM); Contains a
                     prokaryotic lipoprotein signal peptide cleaved between the
                     residues 28 and 29; Localized in the outer membrane;
                     Conserved hypothetical protein"
                     /codon_start=1
                     /transl_table=11
                     /product="Conserved hypothetical lipoprotein"
                     /protein_id="CAZ96769.1"
                     /db_xref="InterPro:IPR000601"
                     /db_xref="InterPro:IPR022409"
                     /db_xref="UniProtKB/TrEMBL:G0LCA1"
                     /translation="MKHILNIEILKNKYYGFLSLVVILSGIACEDTFEYELPEANSKAD
                     LTPPSASFSISPTDDFLTFTFGNNSSSATDYEWDFGDGNTSTDVDGSNTYPDEGTYTVT
                     LTATDKLGVSSTVSQTVEVVEPEIPLAITPVIGGAAFDDGVDDSCLDSRDCWRIEGATI
                     HQTTSDGEADTRGAKYPSGSDNNRVTYQAVKVSPNTKYVLTARYALQADGDSVRASVID
                     GQLSNFSEFADATLLAQESGTVNEGKGNFNTLTVAFETGANGEISILFDHDGNAKDSYL
                     DNVAIAPVEEQP"
     gene            complement(7455..8885)
                     /locus_tag="ZOBELLIA_2620"
     CDS             complement(7455..8885)
                     /locus_tag="ZOBELLIA_2620"
                     /function="Transporter activity"
                     /note="Protein probably involved in nutrient binding and
                     belonging to the SusD/RagB family; Contains a lipoprotein
                     signal peptide cleaved between the residues 19 and 20;
                     Putatively localized in the outer membrane but the
                     determination of the membrane identity for the protein
                     localization is not clear; Family membership"
                     /codon_start=1
                     /transl_table=11
                     /product="SusD/RagB family lipoprotein"
                     /protein_id="CAZ96770.1"
                     /db_xref="InterPro:IPR011990"
                     /db_xref="InterPro:IPR012944"
                     /db_xref="UniProtKB/TrEMBL:G0L681"
                     /translation="MKQFKLITMLLAVVVSFTACEKDFLSPAPTSGVSSETYFSTEEEL
                     ETALINMYDGIQGVNSTDPDDRHGIQYEFYITEMRSDNTRTKSSEGEAAQFESYNITPN
                     NGIIANYYESYYNIIYRANVVLDNLDVIENAATKASYEAEAKFVRAYAYFNLVRLYGDV
                     PLIDRVVGPLETDIQFARVAASSIYDFIKSDLSTAVDGLDNTYRTRASKAAAQTLLAKV
                     YLTLGENYSEAQTLLESVMASGYSLEPDFEDVFYNEENNEVIFSIGYLPNLSSDSQNFS
                     AEWLNGVGRTSGVNYVTSEAVAVLDEFGGDRTAVSYRPDPSQVGQYQVTKYLPNGEDGG
                     SNGKSFDSDPTLAGNDWIVIRYADVLLLHVEAIMAGSASTTASKALTSFQAVRDRAGLT
                     DPVTEVTKEDLLLERRVELAFENHRFFDLVRFGQAESVFSAFSSANNLGYSSTDLLLPI
                     PQNEINLSNGSMSQNPGY"
     gene            complement(8919..12044)
                     /locus_tag="ZOBELLIA_2621"
     CDS             complement(8919..12044)
                     /locus_tag="ZOBELLIA_2621"
                     /function="Receptor and transporter activity"
                     /note="Protein localized in the outer membrane involved in
                     uptake of macromolecules that are too large to diffuse via
                     the outer membrane porins channels or are encountered at
                     very low concentrations; Contains a carboxypeptidase
                     regulatory domain (26-98) and the Plug module (115-224)
                     acting as a channel gate; The signal peptide is cleaved
                     between the residues 21 and 22; Family membership"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q93TH9|1.B.14.6.2"
                     /protein_id="CAZ96771.1"
                     /db_xref="GOA:G0L682"
                     /db_xref="InterPro:IPR000531"
                     /db_xref="InterPro:IPR008969"
                     /db_xref="InterPro:IPR012910"
                     /db_xref="InterPro:IPR014766"
                     /db_xref="InterPro:IPR023996"
                     /db_xref="InterPro:IPR023997"
                     /db_xref="InterPro:IPR027804"
                     /db_xref="UniProtKB/TrEMBL:G0L682"
                     /translation="MNLKTQLTLIALLCLNISLFAQDGYTLSGTVSDADNVPIPGVNVI
                     IANTTKGTSTDFDGLFQINVSEGDILQFSYIGYVTQTIPITGQTELNITMAEDAKQLDE
                     VVVIGYGGTQKKSHLTGSISKVVNENLDQIAVARVDDALVGQVSGVNIQATDGEAGAAP
                     TINIRGVGSMAGDSTPLVVVDGVIVSSDFLGSLNMNDVESFEILKDAASSAIYGSKGAN
                     GIIMITTKGGVEGKTRINYSTYTGFKEARHSEAYTFSIEETAQAQLAATGSLSDRTKYK
                     QLIGVDRSWQDVIFDGGTITSHSLSARGGSEKTKYSTALNYSHDEGVLITDDFKKYGLR
                     LKVDTKINDKFSFGVNFTPSYTNRRRFDGSTHDILRQTNWLPLYHDENTIQFVNRVQDN
                     GAWADVQVGDYAQQYHFDGYDLDAGAPADSGGVSISNTSNANPAAKVLERERYDKKFKM
                     FGSVYGNYNIIDGLSFRSTLSGSYQDTKRTRWQGTLSSRNGAAGASMDEYSQKEIYLIT
                     DNFLSYNKSFGKHDLSVILGVTAETKKSFYSQISGTGYTSDAVKQITNATTISNADAFE
                     WEKNGLSYVSRLNYAYDDKYLASFSFRRDGSSIFGQDFKYGNFTAASVGWNLAKENFLQ
                     DSDIVSTFKLRASYGLTGNDLLNVGSVDPDTSSSTSSLSTGNILVDNYPYLALLGSTTY
                     SVDGSLQAGFNPLNIANAGLQWERLREFNPGLDFGFFNNRVSGSVDYYQRTSDQLLLNN
                     PISVTTGFNSALVNLGEVKNEGYEIELRTKNIVTENFRWASTIIASTNKNTLVDFADSN
                     GQITNVDSKRAAEWINLEGQPISTFYGWVVDKDIPLEYLNDAFHPVGGEAQDVYVKDLN
                     GDGIIDDEDKAALGDPYPELVWSFTNEFNLGKFDFSFMFQGSHGAEIRNMGDQYLFNHF
                     NSSQDFNPETTPNQEFIKEKIFTDDIIQDASYVALRNVNIGYNFPKDVLSDYGVSGLRI
                     YASGQNLMYKTADDYTGFNPESVDRTSPTAYGYQRAGSPIYRTISIGLNLDF"
     gene            complement(12503..13255)
                     /locus_tag="ZOBELLIA_2622"
     CDS             complement(12503..13255)
                     /locus_tag="ZOBELLIA_2622"
                     /EC_number="1.-.-.-"
                     /function="Oxidoreductase activity"
                     /note="Belongs to the short-chain dehydrogenases/reductases
                     (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most
                     dehydrogenases possess at least 2 domains, the first
                     binding the coenzyme, often NAD, and the second binding the
                     substrate. This latter domain determines the substrate
                     specificity and contains amino acids involved in catalysis;
                     Localized in the cytoplasm; Family membership"
                     /codon_start=1
                     /transl_table=11
                     /product="Short-chain dehydrogenase/reductase"
                     /protein_id="CAZ96772.1"
                     /db_xref="GOA:G0LCA2"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:G0LCA2"
                     /translation="MDLKGKIAVVTGGTRDIGKAISLKLAKEGAKVVVNYYNNEANAKK
                     TLDEIRAISGEAIIVKGDMTQKADVDHLVSEAIKAFGGTIDILVNNAGGLVARKSIAEM
                     DEAFFNKVIALNLNSTFLVSQAILPHMKSGASIINIASQAGRDGGGGGSLAYATSKGAV
                     MTFTRGLAKEVGPKNIRVNALCPGMIATTFHDTFTTGDVRKKVAGATPLRREGTAEEIA
                     NTVACLASDETTFITGANIDINGGLAFS"
     gene            complement(13261..13611)
                     /gene="kdgF"
                     /locus_tag="ZOBELLIA_2623"
     CDS             complement(13261..13611)
                     /gene="kdgF"
                     /locus_tag="ZOBELLIA_2623"
                     /function="Pectin catabolism"
                     /note="KdgF is involved in pectin degradation, but its
                     exact function is still unknown. It adopts a Cupin beta
                     barrel fold. Localized in the cytoplasm.; High confidence
                     in function and specificity"
                     /codon_start=1
                     /transl_table=11
                     /product="STP|AraC_binding"
                     /protein_id="CAZ96773.1"
                     /db_xref="InterPro:IPR011051"
                     /db_xref="InterPro:IPR013096"
                     /db_xref="InterPro:IPR014710"
                     /db_xref="InterPro:IPR025499"
                     /db_xref="UniProtKB/TrEMBL:G0L683"
                     /translation="MESFGSSKEFLIGDEIPWETVGEGVQRQIMGYDDKIMLVNVKFEK
                     GGIGPMHEHYHSQVTYVVSGKFKMTIGEETKILKGGDSFYIPPHVMHGTVCQEAGVLID
                     VFSPIREDFMTK"
     gene            complement(13621..15876)
                     /gene="alyA3"
                     /locus_tag="ZOBELLIA_2624"
     CDS             complement(13621..15876)
                     /gene="alyA3"
                     /locus_tag="ZOBELLIA_2624"
                     /EC_number="4.2.2.3"
                     /function="Alginate lyase"
                     /note="Alginate lyase catalyzes the eliminative cleavage of
                     polysaccharides containing beta-D-mannuronate residues to
                     give oligosaccharides with
                     4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at
                     their ends. It belongs to the family 17 of the
                     polysaccharide lyases. Features an uncleaved signal
                     peptide. Features a signal peptide cleaved between residues
                     25 and 26. Localized in the periplasm.; High confidence in
                     function and specificity"
                     /codon_start=1
                     /transl_table=11
                     /product="PL17_2|PL17"
                     /protein_id="CAZ96774.1"
                     /db_xref="GOA:G0LCA3"
                     /db_xref="InterPro:IPR008397"
                     /db_xref="InterPro:IPR008929"
                     /db_xref="InterPro:IPR012480"
                     /db_xref="UniProtKB/TrEMBL:G0LCA3"
                     /translation="MNMTKYIPVLQSLLFVLLLSFSGHAQEHPSLILTKAGVEKIRAEL
                     GNIPIFDATLEKVKAEVDAEIALGIDTPLPKDYSGGYTHERHKRNFFILQKAGVLYQIL
                     NDEKYALYIKDMLFQYEGMYKDLPVHPQTRSYARGKLFWQCLNDSNWLVYVSQAYDCVY
                     DYLSKKERKQLEKNLFRPFADYISIENPQFYNRVHNHSTWGNAAVGMIGLVMGDEELIQ
                     RALYGIEDDGLPIGAKDNDGGFIKVEGQKAGFLANIDEPFSPDGYYTEGPYYQRYAMYP
                     FLIFAEALHNVRPQQKIFEHKDGVLLKSVNTLLSLSDADGEFFPLNDAQKGMSYHSREL
                     VTAVDIAYHYGNHNPQLLSIAEEQGQVLLDDSGLAVALGIREGKSEDFQKKSIKLSDGA
                     NGDQGGVAILRYGNEAMTLVYKYAAQGLSHGHYDKLSFSLYEKGTEILQDYGLARFVNI
                     EQKGGGNYLKENTTWAKQTIAHNTLVQNETSHFEGKYEVGSQHHSELYFFDASNPEVQV
                     VSAKEQNAYPGTEMHRTMALIKTDGFEKPFVLDILRVGSNAANQYDLPFYFKGQVMQTN
                     FDFTTPKSLEPLGSDNGYQHLWSEGLGQPKGDNSQLSWLENGRFYTLTTATNNDDELHF
                     VRIGANDPEFNLRRDAGLIIRRKNTKNTTFVSILESHGHYSPVSEFSVNANSSISKIEL
                     MLDTKEYTAVLIDAKSNTEQTLLILANENKNVNKEHIIEIKGKEYRWTGPYQFIKIN"
ORIGIN
        1 ttacacttct ccggatagaa ttttgttgaa atcgtacgat tcggggtcgg gaagataggc
       61 cttggccgct tcgtagtcgc tctcttcgat atagtgcatg ttctgaaaga agagcctcgc
      121 aaattcagag tctacctcca ctagccgggg ggctattttg ccgtcttcac cttgtaggtc
      181 ttccaaaaac aggggagtga cctcgccacg ggagttcgcc gtaacgatac agccgctaag
      241 gccttggtca aatagctttt taacgccaat tcccaagagc gtacagagcg taaggtcaaa
      301 acctatgggt ctgcaacagc ggagttcata gccaagctct acgggcctac tttttatatg
      361 gatgcccagt tccttcaatt ttacctgaac gagcatatta aagatgtgtg acttgctcac
      421 gttgcccaat tcaggatggc cgtggtcgtc ataggtgaag ttgataccac aatgatcgag
      481 ctcactgtcg ggcatgatgt ggaagacccc ttcacttacc agggcaacac cgtagttgat
      541 gttttttatc tttcgtttta caatagacga tatgatcaag cgtaccacct tgtcaaaagt
      601 aatgggggtc tggttgaaca tttcggggat gaccatcatc ggaaaatggc aactggcagc
      661 gataccgaag gccaaatggc ccgccgagcg ccccatggta gacattacga accagttttg
      721 gctcgtacgt gcatcttcgt atgtggtatt accgatacgt actccttcgt ctttggccga
      781 atgaaatcca aaagttgggt ttcggtcggg caagggcaaa tcgttatcta tggttttggg
      841 cacatgtatg ttcgagatcg atatgttctc ttttaacagg taccctgtaa ttctgttggc
      901 cgtagaggcg gtgtcgtcac cgccaatact gaccaacagt tttacattgt tatcggaaaa
      961 aagtttcgta tttatctttt cgtcgctcgg tttgaaccta ctcatgatca aagtagatcc
     1021 gccacgacta aaaatacgat cggcatgtgc aaaatcgaat tccttgattt gcggttcttc
     1081 ggaaaaaata cctttaaaac cttcgtgaag gccaagtacg cggtagccat ctttgagaaa
     1141 aattttagct acggtgctta taacggcatt gatgcccggt gcgggacctc cgccacaaat
     1201 gatcagtatc gactttttag aagccatctt ttttatttta aaaaattacc gcgctaccct
     1261 tccggaagcg tcgccaccca ttaatttctc tacttcgctt accgtaacca aattggcatc
     1321 acctttaatg gtgtgcttta aacaagatgc ggccacggca aaatcgaggg cattttggtc
     1381 gtcttcgggg tattgcaaaa gaccgtatat caatccaccc ataaaagaat cgccaccacc
     1441 tacgcggtct acgatatcgg taatctgata ctgtcgggtc tcgtacattt ttttaccatc
     1501 gtaaagtaca ccggcccatg tgttgtgcga tgcggatatg gagcccctta aagtggttat
     1561 cacttttttg gctttcggga actttttcat catttgttta cagaccgata gaaaagcctc
     1621 ggcctttacc tcactgcctt gtttgtgcac gtcaagtcct tcaggatgga tcccgaaatg
     1681 tttttcggca tcttcctcgt tgcccaagat aatgtcgcag taggaggtaa gctcggtcat
     1741 tatggcctcg cggtcaccac catagttcca gagcttggcc ctgtagttca ggtcggtgga
     1801 aatggtaatg cccatatcgc tggccacttt tacggcctcc aaacaaacat cggcggcact
     1861 ctgtgaaatg gcaggggtaa tgcccgtcca atggaaccat ccggctcctt caaagacttt
     1921 tttccagtcg atcattcctg gttcaatttc ggaaatggcc gaatgggcac ggtcgtagac
     1981 taccttgctt cctcggctta cggcaccggt ttccaaaaaa tagattccga gacggtcgcc
     2041 accaaaaata atgttttggg tgttgacgcc cctttttcgc atttccatca aggcgcattc
     2101 accgatgtcg tttttgggca aacgggtaac aaaatctacc ggaaccccgt aattggcgag
     2161 tgataccgcg acattggatt cgccaccacc gtaaacaacg tcaaagctgt tggcctgtga
     2221 gaagcgtaag aatcctggag gtgctaaacg gagcatgatc tctccgaagg ttactacttt
     2281 tttcatttta aatcgtgtta ctatattact gtttttaagt gctattttag atataagcgg
     2341 ttagattcct aaagcttgcc cacccccaat ttgtatggtt tcggcggtaa tgaattttgc
     2401 atcgctgctt gctaggaaag atactacacc ggctacatct tcgggttgac ctaatctgcc
     2461 cagcataatg ctgttggccc atgaagcaaa aacttcgggc ttggtagctt tgatctgtgc
     2521 gtgaaatggg gtgtctatgg tacctgggga tactgcattt acccgaatcc catattcggc
     2581 caaatcttta gccaatgctt tggtaatagt gttaacaccc gctttcgagg ttccgtagat
     2641 tcccgctcca ggtccaccag cggtccaagc tgcatttgaa gtataattta tgatagaagc
     2701 gccttctcct ttttttagat aaggaatagc cgcccgtgag gcaaaaaagg tagaatctag
     2761 attcagtgcc attaccgatc ggtaaaactc cgtagtcatt tcctcaaatc ttgatcgacc
     2821 tcctagacct ccggcattgt ttacaagggt atctattttc ccgtatttct cgccaattgc
     2881 cttaatattc ttggtgacgg cttcctcatt ggtaacatca aaactataat attcagcttc
     2941 aataccttct gaagtaagtt cctttaccct ttctgcgccg gcttcatcgt ctataccatt
     3001 taaaataacg gtatacccat cttgccctaa tctttttgct acggcaaaac ctattccacc
     3061 tgttgctcct gttattactg ctacttttct tttcatttgt atgttagtta ctgttaatga
     3121 tttttttttt gattaaactg actcaagttc tacggggcgt atccgcttta tcaatccata
     3181 gatcgatagt accgctaggg gagccagtac ggcaattaca ataaatgcgg gagtatatga
     3241 tactgatgct atcattggaa tcaaagagtt cataatgatg accgagacag ctgccacggt
     3301 accggccaaa ccggccaagg tgcccacgga gggtccgcgg aacaggtcgc ttgaaatggt
     3361 ctggatatta ccaatggcaa actgaaatcc gaagagtacg acagccacga tatagataaa
     3421 ggtcatcgga ttcttttcgg ttaccaggaa tatgatgccc aacaagccta agaaaatcaa
     3481 tgcgccccca atggttatgg taatctttct cgcggcatcc accgttttgg tttccattaa
     3541 tttaccgctg taccagccgc cgacaatact tcctgccata ccgcccaaat acgagatcca
     3601 aatagtagat cctatttctt cgatactgaa accgaacttc gagttgaggt agagtggcat
     3661 ccatcctaca aagagccacc atatcggttc gatgaaaaaa cgggacatga gtacgcccca
     3721 agattcctta taactcaata ttttaagtac cgaaagtcct ttttccttct tctctggcga
     3781 actaaaggca atttgatcgg caaggatgat cttttgttct tcttcggtga tccaagggtg
     3841 gttttcaggc ttggccttgt tgataaccaa ccaaggaatg acccaaagca agccgatggc
     3901 accgatgatg ataaaggtgg tgcgccagcc gaaatgcccg tatagatagg cgataagtac
     3961 cggggcgata acacttccta gtgaagctcc cgcgttaaaa ataccttgtg caatggcccg
     4021 ctgtttaacg gggaaccatt caccgttgct ctttaccgct cctggccagt ttccggcttc
     4081 tcccaagccc aacatggccc tgaagagcgt taatgaaacc aaacctctgg cgaaagcatg
     4141 gaaaattgat gctacggacc acacaactat ggagaccaca aaacccatac gggtgccgat
     4201 gatatcatag agcttgcccg ataaaaactt accggcggca taggtgatca taaaaacatt
     4261 gagcattatg gcgtagtcgg actcgtccat acccaaatct ttacccattt caggccacat
     4321 aacaccaaaa gcggtacggt ctatatagtt aatgaccgtt gccaaacaaa ttagggcgat
     4381 aacccaccat cttaaacctt tgactttcat cttcgttctt ttaaattatt cattgtattt
     4441 aggcagacga atagcaggcc tagtcctttg gggataggca ataagcaatt caggatacct
     4501 gtatttaagg gacttaaata cgtattatgt aaataggata tggcatgggc ggcttagccg
     4561 tctaccttca taggataagt tgttttttag tattattagt cttcccttca gtatttgaga
     4621 tcaggataaa tcgtgcactt ttatcctttt ccaattttaa ttttacggtc tttgccatag
     4681 atgtaatcgt acaatttgct aaagtgcaat ttcatctttt ccttggcgag ttgtgggttt
     4741 tggtccttaa tggccatata gatgtcttca tgctttttta cctctgccaa ggctacatcg
     4801 ccatcacaaa cgcgatcttg gtcataggcc acgataatct cgggggtaat caatagcatg
     4861 agggtgttca tggtgctgtt cttgcttgcc gaagcgatcg ccaaatgaaa gagtaaatct
     4921 tcttcaaggc aatcatcacc ggctatcatt tttgttttgt aggcattaaa ggcctgttta
     4981 aggcgttcta agtcttcctc ggttcttctg agggccgcta attttacggt tttgagttca
     5041 agtaaaatac gggtttcgac cagtgattta aaatcttgct cttccaagct aagaatatcg
     5101 tcgatcatac cgttcatggc aatttggcca atattggcga tgaaagtccc gctttggggt
     5161 ttagaattca atatgccgta gaattccaat ttttgaatgg cttcgcgaac gttacttctg
     5221 ctaacaccga acttttctga gagtacccgc tcggcaggta gtttatcccc aggttcaagg
     5281 tttttgtaat tgataagatc acgaatcttg gcgatgatcc cattttggat atccctattt
     5341 tcgtgtttgg tcaatatttc tagtttcata gcgtaagcgg ttcaaaattg gttaaccaga
     5401 ttggtttgtt aaaattataa aaaaataacc tactaaaaaa gtattttttg ttttataaaa
     5461 atcagctttc atggggcatt gaagcgattt ttagaattct accgacccgt ggtgagcggg
     5521 tcggcaaaat tactgccaat ctaactcaaa acaacataat tttaattctt attttatata
     5581 gtaggtactt cgtttttata gaaaaaccaa ctagtgtata acttctaaat cgtaaaattt
     5641 caccttggcg taactccctt catccttact ttgaaagtag tttcctgcct tgaagtaatt
     5701 ttcgaagatt ccccaccttt tgatattgac atcatcatag accgcatatt ccgtattgtt
     5761 cataatgact accaatttcc ctttggaaac cttgacctca agtttgaact ttttaaatcc
     5821 gacatagtcg gggaaggtat atccctcatc atcgccccaa gcttcttcgt gtaaaatttc
     5881 ttgatccgaa gcgcttttgt tcttcagtac cttagtcttt acccgtacat agcctttgtc
     5941 ccaatatatt tttaatatgg gcggggcatt gttgtctttt gccccaatga gctctttttg
     6001 ctcgttggtc aatcggccat ggatttgcat gattatggtt cgatggtact tgccatcgga
     6061 atctttggtg atttcgtcta ccgccaaagt tcccttcatc cttcctcctt gttcaaatgt
     6121 ccaattcaca ttgttgtcac cgggtaccat ttgctcgcgt agctcgcttc ttgaatactt
     6181 ggtgttggcc gtagttgaat tcggaaaagc ataaaatacc aatgaaccat cggtggaatc
     6241 attatagaaa tagggacgta cgacttcatt cgtagcgtat tccaaaattt cgggaggctc
     6301 aacttctgtt ggttttccaa caggaagggt aagcttccaa tgactcaggt ctattttggg
     6361 taacttatat ttcttgatgt cgacactctc ggtttccgga gtgtctgaat tcgcataggg
     6421 cccatcttga tgatttgccg caactgccaa gtcattactg tcttggcagt ttccggcaga
     6481 aaccaaaact aaactcaaat aacaagctct aaaaaagttg cttaaaaact gcattttttt
     6541 atttaaggtt gttcttctac tggagcaatg gcaacattat ccaagtagga atcttttgcg
     6601 ttaccgtcgt ggtcgaacaa tatgcttatt tcaccattgg cacctgtttc gaaggctacc
     6661 gtaagcgtgt taaagttgcc tttgccttca tttacggttc ctgattcttg tgccaataag
     6721 gtagcatcgg caaactcgct gaaattactc agttgtccat cgataacact tgcccgtaca
     6781 ctgtctccgt cagcttgcaa tgcatatctg gcggtcaaga catatttggt gttcggggaa
     6841 actttaacgg cttgataggt gacacggttg ttatcgcttc cggaggggta tttggcacct
     6901 cttgtatcgg cttccccgtc actggtagtt tggtgaatgg tcgccccttc aattctccaa
     6961 caatccctac tgtcaagaca actgtcatcg acaccgtcat caaaagcggc cccgccaatt
     7021 accggtgtta tcgctagtgg aatttcaggt tcaactactt caacggtttg tgataccgta
     7081 cttgatacgc ctaatttatc ggtagcggtc aaggtaaccg tgtaggttcc ttcatctggg
     7141 taggtattgc tgccatctac atctgtagac gtattaccgt cgccaaaatc ccattcataa
     7201 tcagtagcac tactggagtt gttaccaaag gtaaacgtca ggaagtcatc ggtcggcgat
     7261 attgaaaagc ttgccgatgg aggggtcagg tcagcctttg aatttgcttc gggcagttcg
     7321 tactcgaagg tgtcttcaca agcaataccg gataggatta cgacaagcga tagaaatccg
     7381 tagtacttgt ttttcaatat ttcgatattt aaaatatgtt tcatttttta cagtttttat
     7441 ggtaaaccaa gtgattagta tcccggattt tgactcattg atccgttgct caggttaatc
     7501 tcgttttgcg gaataggcag taacaagtcg gttgaagaat acccaaggtt attcgctgag
     7561 gagaaggcgg aaaaaacgga ttccgcttga ccaaatcgaa ccaaatcgaa gaaacgatga
     7621 ttctcgaagg ccaattcgac ccttctttcc aacaacaaat cttcttttgt aacttcggta
     7681 actgggtcgg taagccccgc cctgtcgcgt acagcctgaa acgaggtcaa agcttttgaa
     7741 gcggtagtgc tggcgctacc ggccataata gcttctacat ggagaagaag tacatcggcg
     7801 tatcggatta cgatccaatc gttgccagca agtgttgggt cgctatcaaa gcttttccca
     7861 ttcgatccgc catcttcgcc gttcggaagg tatttggtta cctgatactg acctacctgc
     7921 gaagggtcag gcctatatga gaccgcggtc ctatcacccc caaattcatc taatacggca
     7981 acggcttcac tggttacata gttcacccca gaagttctac ctacaccgtt caaccattcg
     8041 gctgaaaagt tttgactgtc tgaacttagg tttggaaggt agcctatcga gaagataact
     8101 tcattgtttt cttcgttgta aaatacgtct tcaaagtcgg gttctaggga atagcctgaa
     8161 gccattacac tttccaatag ggtttgggct tctgaatagt tttctcccaa ggtcaaatat
     8221 acttttgcca aaagggtctg tgcagcagct ttggaggctc ttgtgcggta ggtgttgtct
     8281 agcccatcaa ctgcagtgga caagtcactc tttataaagt catatataga agatgccgca
     8341 acccgggcaa attgaatatc ggtttccaaa ggtccgacta ccctatctat caaaggaaca
     8401 tcaccataga ggcgcaccaa attgaaatag gcataggctc taacgaattt agcttcggct
     8461 tcatatgatg ctttagtcgc tgcattttct attacatcaa gattgtccaa tactacattg
     8521 gccctataga taatgttgta atagctctcg taataattgg caataatacc gttgttcggt
     8581 gttatgttat aactttcgaa ttgtgctgct tcaccctcgc tacttttggt acgggtatta
     8641 tcgctccgca tttcggtgat gtagaattcg tattgaatac catgtctgtc atcgggatcc
     8701 gtcgaattta ctccttgaat accgtcatac atattgatca aagcggtttc taattcttct
     8761 tctgtagaga agtaggtttc cgaagatact cctgatgttg gtgcgggaga caagaagtcc
     8821 ttttcgcagg ccgtaaagga tacgactacc gccagaagca tcgttattag tttgaattgt
     8881 ttcataatat atcgtgaatt ttgtttatac tgttctgatt aaaaatcaag gttaagtcct
     8941 atagaaatcg ttctatatat aggggaacct gctctttggt aaccgtaagc tgtaggactt
     9001 gttctgtcta cggattcagg attgaaacct gtatagtcat ctgccgtctt gtacataagg
     9061 ttttggccac tagcatatat tcttaaacca gacacaccat aatcactcaa aacgtctttt
     9121 gggaaattgt atccaatatt tacgtttctc agtgctacgt acgaagcgtc ttgaataata
     9181 tcatcagtaa agattttttc tttgataaat tcttggttag gcgttgtttc aggattgaaa
     9241 tcttgagaag aattgaaatg gttgaacagg tattggtctc ccatgttcct gatttcggcc
     9301 ccatgtgaac cttggaacat aaaactaaaa tcgaacttgc caagattaaa ctcgttggtg
     9361 aaactccaga ctaattctgg atatgggtct cctaaagcag ctttgtcttc atcatcaata
     9421 ataccatcgc cgtttaaatc ctttacgtaa acatcttggg cttcgccacc aacagggtgg
     9481 aaagcatcgt tcaagtattc aagcggaatg tctttgtcga cgacccaacc gtagaatgtg
     9541 gaaatcggtt gtccttcaag gttgatccac tctgctgccc ttttagagtc tacatttgta
     9601 atttgaccgt tggagtcggc gaagtctact aaagtattct tgttcgttga agctatgatg
     9661 gtagaggccc acctgaagtt ttctgtaaca atgttctttg ttctcagttc aatttcataa
     9721 ccttcgtttt tgacttcacc taaattaaca agggcactgt taaaacctgt agtcactgaa
     9781 atcggattgt tcaataatag ttggtcactg gttcgttggt aataatcaac ggagcccgat
     9841 accctattgt taaaaaagcc gaaatccaaa ccagggttga attctctcaa acgctcccat
     9901 tgcagtcccg cgttggctat gttcagaggg ttgaagcccg cttgtaatga accgtctacg
     9961 gaataggtcg ttgagcctaa aagggccaag tatgggtagt tgtctaccaa gatattacct
    10021 gtgctcaaag aactcgtact actactggta tcgggatcaa cactacctac gttgagcaaa
    10081 tcgtttcctg ttagaccgta actggccctt aatttaaaag tgcttacgat atcactatcc
    10141 tgtaagaagt tttctttggc aaggttccaa ccaacagagg cggcagtaaa attaccgtat
    10201 ttgaagtctt gaccgaagat agagctaccg tcccttctaa agctaaatga agctaggtat
    10261 ttatcgtcat aagcatagtt cagtctggaa acgtatgata ggccgttctt ttcccattca
    10321 aaggcatctg cgtttgaaat ggtcgtggcg ttggtgattt gcttaacggc atcggaagta
    10381 taaccagttc cgctaatttg tgaataaaac gattttttcg tttcagcggt tacacctaaa
    10441 attacactta gatcatgttt accgaaactc ttgttatagg atagaaagtt gtcggtaata
    10501 aggtagattt ccttttgtga atattcatcc attgaggcgc ctgcggcacc gtttctactg
    10561 gatagggtac cttgccatct tgttcttttg gtgtcttgat acgaaccgga aagggtagat
    10621 cggaaactta aaccgtcaat aatgttgtaa ttaccgtaaa cgctaccgaa cattttgaat
    10681 tttttgtcgt aacgttcgcg ctccaatact ttggccgcag ggttggcatt cgaggtgtta
    10741 ctgatactta ccccaccaga atctgcaggg gcaccggcgt cgaggtcgta gccgtcaaaa
    10801 tgatattgtt gtgcgtaatc accgacttgc acatcggccc acgccccatt atcttgaacc
    10861 ctatttacaa attgaatagt gttttcatca tggtaaagtg gtagccaatt ggtctgtctt
    10921 aatatatcgt gggtacttcc atcaaacctt cttctgtttg tgtaagaagg ggtgaagttc
    10981 acaccaaagg aaaacttatc gtttattttg gtatctactt taagtcttaa tccgtatttt
    11041 ttgaaatcat cggtaattaa gacaccttcg tcatgtgagt agttaagggc ggtgctatac
    11101 ttggtttttt cacttccacc gcgagccgat agggaatgac tggtaatggt accaccgtca
    11161 aaaatgacat cttgccaaga acggtcaaca cctatgagtt gtttgtattt tgtcctgtcg
    11221 gataatgacc cggtggcggc caattgggct tgtgcagttt cttctattga aaaggtatac
    11281 gcttcactat gtctagcttc tttaaaacca gtataggtac tatagttgat acgggtctta
    11341 ccttcaacac caccttttgt ggttatcatg ataataccgt tggcaccttt tgaaccgtaa
    11401 atggcagatg atgctgcatc ctttaaaatc tcgaaagact ctacatcgtt catgttcaat
    11461 gaacctagga agtctgaact tacaattaca ccatcgacaa cgaccaatgg ggtagagtca
    11521 ccggccatag agcctacacc cctgatattt atggtaggag cggctcctgc ttctccgtcg
    11581 gtggcttgta tgtttacccc cgatacctgc ccgaccaagg catcatcgac acgagctact
    11641 gctatttgat cgaggttttc gttgactact tttgagatcg aaccggtcaa atgtgatttc
    11701 ttttgggttc ccccgtaacc tataaccacc acctcgtcta attgtttggc gtcttcggcc
    11761 atggttatat ttaactcggt ctggcccgtt atgggtatgg tttgtgtaac atagccgatg
    11821 tatgaaaatt gaagaatatc gccttctgaa acgtttattt gaaataatcc gtcaaaatct
    11881 gttgaggtgc ctttggttgt attggcgatt atgacgttaa ctcccggtat tggaacattg
    11941 tccgcatcgg aaaccgtgcc tgacagtgtg taaccgtctt gggcaaatag cgatatattg
    12001 agacacaata atgctattag tgtgagttga gtttttaaat tcatttgtaa taatgttaag
    12061 ttagtaatgt tcatcggtta aggtccgata cctaaatgag attgtataga atcgcatttg
    12121 ttcttcaact tactagtgca cgttactcat taatgtccct gaattttgta cttttgtaat
    12181 gagcgtgtat agtaaagtgt acatgttctt agtattactt cccttcagaa tgaagtaaat
    12241 ttttttaaaa ggatgggcgt gcacccatcc tttttttatt gaaaatatcc tatggtatca
    12301 ttagtatttt tcttttatta gtattagctt ttctacaagt tttaattggt tttccatatt
    12361 ggttaaccaa tttggtttac caaatataac ttaatagttt gttaaaaaaa aattaatgtc
    12421 aaattttatg atgttaattt taggtatcta atacttaaag gagcactaag ttgccatatt
    12481 ggtaatttga ggccgttcta gcttatgaaa aggcgagtcc gccattgatg tcgatattgg
    12541 ccccggtaat aaaagtagtt tcgtcggaag caagacaagc tacggtattg gctatctctt
    12601 cagccgtacc ttccctgcgc aatggggtgg ctcccgctac ctttttacgt acatcgcccg
    12661 tagtgaaagt gtcgtgaaag gtcgtggcga tcattcctgg gcaaagggcg ttgacgcgaa
    12721 tattcttggg gcctacttct ttggccagac ctcgtgtaaa ggtcataacg gcgccttttg
    12781 aagtggcata ggccaaagaa ccgccgccac cgccatcacg gcctgcttgc gatgcaatgt
    12841 ttatgatcga ggcaccagac ttcatatggg gcaatatggc ttgtgagacc agaaaggtgg
    12901 agttgaggtt caaggcaatg accttattaa agaaagcctc gtccatttcg gcaatactct
    12961 tacgggctac caatccaccg gcattgttta ccaagatgtc aatggtacct ccaaatgcct
    13021 ttatcgcttc cgataccaaa tggtcaacat cggccttttg ggtcatgtcc cctttaacga
    13081 ttatggcttc gcccgaaatt gcccttatct catcaagggt tttctttgcg ttggcctcgt
    13141 tgttgtaata gttgactact actttggctc cttcttttgc caatttaagt gaaatggcct
    13201 tgccaatatc ccttgttccg cctgtgacaa cggcaatttt tccttttaaa tccatagtta
    13261 ttatttagtc ataaaatctt ccctgatcgg gctgaaaaca tctattaata cacctgcttc
    13321 ttgacaaacg gttccatgca ttacgtgggg aggaatgtaa aacgaatcgc ctccttttag
    13381 tattttggtc tcttcaccta ttgtcatctt gaattttccg ctaacgacgt aagttacttg
    13441 tgagtggtag tgctcgtgca tggggcctat accgcctttt tcaaatttta cgtttacgag
    13501 catgatctta tcgtcgtagc ccataatctg acgttgtacg ccttcgccaa cggtttccca
    13561 ggggatttcg tccccgatta aaaactcttt acttgatcca aaactttcca tagtttaatt
    13621 ttaattgatt ttaataaatt gatagggccc cgtccaacgg tattccttgc ccttgatttc
    13681 tataatatgc tctttattga catttttgtt ttcattggcc agtatcaata gtgtttgttc
    13741 ggtattggac ttggcatcga tcaatactgc cgtgtactct ttcgtatcta acataagctc
    13801 gattttagag attgaactgt tcgcatttac cgaaaactct gaaacaggac tataatggcc
    13861 gtgtgattct agtatcgata caaaggtggt gttctttgtg ttctttcttc tgatgatcaa
    13921 accggcgtcc cttcttaggt tgaactctgg gtcattggcc ccgatgcgta cgaaatgtag
    13981 ctcgtcgtcg ttgttcgttg ccgtggtcag ggtatagaag cgtccgtttt ccaaccagct
    14041 gagctgggag ttgtcgcctt tgggctgtcc taggccttct gaccaaaggt gctgatagcc
    14101 gttatcggaa cctaggggtt ccaagctttt tggggtggtg aaatcaaaat tggtttgcat
    14161 cacctgtcct ttgaagtaga agggaaggtc gtattggttc gcggcattcg aaccgaccct
    14221 taggatatcg agtacaaagg gcttttcaaa accatcggtt tttatcaggg ccatggtccg
    14281 atgcatttcc gtaccgggat aggcgttttg ttctttggcg ctcaccacct gtacttctgg
    14341 gttggaagca tcaaaaaagt agagctccga atggtgttgg ctccccactt cgtactttcc
    14401 ttcaaaatgt gaggtttcgt tttgtacaag ggtattgtgg gctatggtct gtttggccca
    14461 ggtcgtgttc tccttgaggt aattgccccc gcctttttgc tcgatgttga caaaacgggc
    14521 gagaccgtaa tcttgtaata tttcggttcc cttttcgtaa agtgagaacg atagtttgtc
    14581 gtagtgccca tggcttagcc cttgcgccgc atatttgtag accaaggtca tagcttcgtt
    14641 gccgtacctg agtatggcca cgcccccttg gtcgccgttg gccccatcgc taagcttgat
    14701 cgattttttt tggaagtcct cgctttttcc ttccctaatg cccaaggcta cggccagccc
    14761 cgaatcgtcc aataaaactt ggccctgttc ttcggctatg ctgagcaatt gcggattgtg
    14821 gtttccgtaa tgataggcga tatcaacggc ggtaaccagc tctcgggagt gatatgacat
    14881 acctttttgg gcgtcgttca agggaaagaa ttcgccatcg gcatcggaga ggctcaaaag
    14941 cgtgtttacc gattttagca atacgccatc cttgtgttcg aatattttct gttggggcct
    15001 tacattgtgc agggcctcgg caaagatcaa aaaggggtac atggcatacc tttggtagta
    15061 agggccttcg gtataatatc cgtcagggga aaaaggctcg tctatattgg ccagaaaacc
    15121 ggctttttgg ccttccacct ttatgaatcc tccgtcattg tccttggccc cgatcggcaa
    15181 gccgtcgtct tcaataccgt agagcgccct ttggatcaac tcctcatcgc ccattaccaa
    15241 accgatcatc cctacggcgg cattgcccca agtactgtgg ttgtgtacgc ggttgtagaa
    15301 ttgcggattt tctatggata tgtaatcggc gaatggcctg aaaaggtttt tttcaagttg
    15361 cttgcgttct tttttcgaaa ggtagtcata tacgcagtca taggcctgac tcacgtaaac
    15421 cagccaattg gaatcgttta ggcactgcca gaacaacttt ccccgggcgt aagaacgcgt
    15481 ttgtgggtgt accggtaggt ctttgtacat tccttcgtat tgaaacagca tgtcctttat
    15541 gtatagggca tatttctcat cgtttagaat ttggtacaat acccctgctt tttgaaggat
    15601 gaaaaaattg cgcttatggc gctcatgggt atagcctccg gaataatctt tagggagggg
    15661 cgtatctatg cccaatgcta tttcggcatc cacttcggcc tttacctttt ccaaggtggc
    15721 gtcaaaaatg gggatgttgc ccaattcggc ccttattttt tctactcccg ccttggtcag
    15781 tatcagactc gggtgttctt gtgcatgtcc gctgaaggaa agcaacagaa cgaagaggag
    15841 ggattgtagt acgggtatgt atttggtcat gttcat
//
