LOCUS       CP028460               16619 bp    DNA     linear   BCT 22-OCT-2018
DEFINITION  Bifidobacterium animalis subsp. animalis strain CNCM I-4602
            chromosome, complete genome.
ACCESSION   CP028460
VERSION     CP028460.1
DBLINK      BioProject: PRJNA445301
            BioSample: SAMN08774047
KEYWORDS    .
SOURCE      Bifidobacterium animalis subsp. animalis
  ORGANISM  Bifidobacterium animalis subsp. animalis
            Bacteria; Actinobacteria; Bifidobacteriales; Bifidobacteriaceae;
            Bifidobacterium.
REFERENCE   1  (bases 1 to 16619)
  AUTHORS   Egan,M., Bottacini,F., O'Connell Motherway,M., Casey,P.G.,
            Morrissey,R., Melga,S., Faurie,J.-M., Chervaux,C., Smokvina,T. and
            van Sinderen,D.
  TITLE     Staying alive: Growth and survival of Bifidobacterium animalis
            subsp. animalis under in vitro and in vivo conditions
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 16619)
  AUTHORS   van Sinderen,D., Chervaux,C. and Smokvina,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-APR-2018) School of Microbiology, University College
            Cork, Western Road, Cork ND, Ireland
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method        :: SMRT Analysis v. 2.3
            Expected Final Version :: yes
            Genome Coverage        :: 400.0x
            Sequencing Technology  :: Pacbio SMRT sequencing
            ##Genome-Assembly-Data-END##
FEATURES             Location/Qualifiers
     source          1..16619
                     /organism="Bifidobacterium animalis subsp. animalis"
                     /mol_type="genomic DNA"
                     /strain="CNCM I-4602"
                     /host="Homo sapiens"
                     /sub_species="animalis"
                     /db_xref="taxon:302912"
                     /country="France"
                     /collection_date="01-Oct-2014"
     gene            1..1353
                     /locus_tag="CNCMI4602_0516"
     CDS             1..1353
                     /locus_tag="CNCMI4602_0516"
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="AYN23376.1"
                     /translation="MAGLWDIDKIEYVGRTKGLQEGLGFQYYDADKVVAGKKMKDWLRF
                     GVAWWHTFDAPLTDPFGDGTAQRPWDGKYSDPMDNALAKVDYAFEFFTKLGAEYFCFHD
                     RDIAPEGDTLRETNANLDRVVDKIEENMQSTGVKLLWNTSSLFTNPRFVAGASTSPFAD
                     VYAYAAAQLKHSLEIGKRLGAENYVFWGGREGYENLWVTDMKREQEHMAKFFHMCADYA
                     KQIGMDAQFLIEPKAKEPTTHQYDFDAATACNFLRAYDLIDVFKLNLEGNHANLAGHTY
                     QHEIRVARDNGVLGSLDANQGDMLLGWDLDEFPTNLYETTSVMWEVLDEGQIGPHGGLN
                     FDAKPRRTSFSAEDLFRAHIAGMDTFAAGLLVADKMHQDKYIEDLVANRYGSYDSGIGK
                     SIDDGTATLESLNDYAIDMPQSEIIASTHPDHLEDVKATINNYIIDALANA"
     gene            1783..3465
                     /locus_tag="CNCMI4602_0517"
     CDS             1783..3465
                     /locus_tag="CNCMI4602_0517"
                     /codon_start=1
                     /transl_table=11
                     /product="GH43|GH43_12"
                     /protein_id="AYN23377.1"
                     /translation="MTATTATIDITNPVLRGMYPDPSWMWDERGERVALVNSSFELVPG
                     LPIHVSDDIANWELAGNAVDEAMAQRLLIPFVLDSGGLYAPTLRMIRGKYVIACTVARI
                     DLDAAAAAGVDPESIEAARASQGNFIIEADALEGPWRGPYWIEGAEGIDPDIFEDLDGS
                     VYWTQTRPAVRPRWEGQTEVWTQRIDPETWRLCASHDADGDYGKTVLWTGYGVEAVWAE
                     GPHLYRIGDWVYLMTAEGGTSFDHSEMTMRTWAPDGLGPAIESLQGQAHADGTEPRAPR
                     ADERSVVGRYARLFHPCKKNPFLTHRHLGLEERVQCVGHADLLHHPRLGWWAACLGSRE
                     TPTADHGALSFLGRETFVAPVDWQHDPAQWSLESNGPAQRRTDDPGWPILAGGAGRLAQ
                     TLRIDAADGTLLDMCIGPCESQAVVDARMPFAVGDGEGAAVRADGTVYRRMPEDRCVVL
                     CPPRGTVRIRQDGRHTLSVATDSASVQWALGEGTERREGMVPIPEGEPGSVMLVFDKGM
                     ARVVVAQSAEQAWTAPAVEVIDVAPLSTEWSGGFVGCLVGCDA"
     gene            complement(3630..4646)
                     /locus_tag="CNCMI4602_0518"
     CDS             complement(3630..4646)
                     /locus_tag="CNCMI4602_0518"
                     /codon_start=1
                     /transl_table=11
                     /product="DBD-Pfam|LacI,DBD-SUPERFAMILY|0036955"
                     /protein_id="AYN23378.1"
                     /translation="MSESKVRLADIAKHTGYSLATVSKALNGRSDISDEARTAIDQALK
                     ASGYQRRGQKAAGQRYIEVVFQDLDTIWALEVLRGVLRETRHSPDISVITTESGTRQHP
                     DDDWITGMLRRRPFGVIFIFANLTEKEKTKLQANGIPYVIFDPSGEPSNDDFSVQADNW
                     AGGVLATRHLLALGHTRIGIITGPEEMMCSRARLDGYTSALAEQGIALDPELVTEGDFT
                     TEGGYAQAMALLENPNRPTAIFAGSDLQAMGVYEAARQNRLRIPEDLSVVGFDDVQTSA
                     FLGPALTTVRQPLHDMAAVSTRMLIDTAEGRPTQHHVILPTTLVVRGSTARLASEAR"
     gene            4978..6255
                     /locus_tag="CNCMI4602_0519"
     CDS             4978..6255
                     /locus_tag="CNCMI4602_0519"
                     /codon_start=1
                     /transl_table=11
                     /product="STP|SBP_bac_1"
                     /protein_id="AYN23379.1"
                     /translation="MKLKTLAAATLAVATVLGMSACGGSGSSSDDKTITFWHNASAGKG
                     RQYWENLAKSFEEANPGTKVEIQAIQNEDFAGKLQTAMQDPASGPDVFMSLGGSKTQEM
                     IDAGQVMDLTDKISDTVKTDMKSTLSAATFDGKVYGVPVSVEPGGMWYSKDLFKKAGIS
                     GVPATYEDLLADAKKLKDSGTDAIALGAKDAWPAAHWYYWLVLRECSPAVYDKSVQDHD
                     FSNACWVNAGKKLQELKDLKVFNDGFLTTTAQQGANSSAGLLANHKAAMELMGAWEPGV
                     LGDLTPDQKPMADLGFFAFPEVAGGEGEPGALMGGVTYFCVNPKASQASIDFVNYMGEK
                     KNQEDYAEAFSTIPASEPARGVVTDESLKQVIEYLDKAPSMQLWMDTALGTNIGNALNA
                     AVVNMLSGQGSPEDIVKAMEDAAQKG"
     gene            6363..7421
                     /locus_tag="CNCMI4602_0520"
     CDS             6363..7421
                     /locus_tag="CNCMI4602_0520"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q72H67|3.A.1.1.25"
                     /protein_id="AYN23380.1"
                     /translation="MTEMNDAVAVGRPVAETKKRGGERKPSNGKGRRNLEIFILSAPAI
                     ILFCCFVIFPIILGAYYGFYQWKGFGTPAENGKFVGLQNYIVALKDPNFQQAILHTFEI
                     VIGSLVIQGPLAILFALLLNQKFKGRGLIRTLIFVPYVVSEVIVGTGWSLLLQKKGAVN
                     QILESLGMHGVDWLADPKVAIWTLLLLISWKYIGFAVILMLAGMQSIPEELYEAAKVDG
                     AGFWQIQKSITLPLLAPTLRIWVFLSMIGSLQLFDLVYIIWGQYVSTTAGVSTMATYMV
                     REGRGAGNYGYGSAVALIIFVISLIVALTYQHFVLNRDLDGALTEKKASKKRRKRQTAE
                     DEALAVAMEGVK"
     gene            7423..8292
                     /locus_tag="CNCMI4602_0521"
     CDS             7423..8292
                     /locus_tag="CNCMI4602_0521"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q8RJU8|3.A.1.1.18"
                     /protein_id="AYN23381.1"
                     /translation="MSAATAYSKKNGFHKSAKTPWGNPIVYFFSLVLVAICIVPVLYII
                     FGGFRTNAQITNNPAGLPNPWVISNYKDVITSDMFWTELGNSLIAGICTMVGVVVLGIM
                     VSYVIARYKFRYSALMYALFSAGLMFPMTVGITPLYLMIRNLGLSNSLAGIILPGIAFG
                     LPQTIIILVPFLQSIPMELEEACLLDGCSRLGFFWRMVIPLSMPGVATTGILTFVGSWN
                     GYMLPLFVLSDESKYTLPLGVQMFSSQHSVDTARVLAFTSLAMLPALICFTIFQKKIVG
                     GLTGAVKG"
     gene            8370..9995
                     /locus_tag="CNCMI4602_0522"
     CDS             8370..9995
                     /locus_tag="CNCMI4602_0522"
                     /codon_start=1
                     /transl_table=11
                     /product="GH43|GH43_11"
                     /protein_id="AYN23382.1"
                     /translation="MKIENPVLPGFNADPSMIRVGDTYYIANSTFEWWPGVRLHESKDM
                     VHWRLLPSPLNRRSQIDMRGNPSSGGVWAPDLSYADGKFWLVYSDVKIVNGAFKDCTNY
                     LVTAEDIRGPWSEPIRINGVGFDASLFHDDDGRKYLVQQTWDFREYNHPFDGITLTEFD
                     VETMRLRPETERTIWRGTDVKLVEGPHLYKINGMYYLFCAEGGTVWTHQEVVARSATLD
                     AMSFEGSPYNPFISNFDTPRSYLQKQGHGALVDTPSGEWYYASLCGRPWHHENESVTDP
                     RGWCTLGRETSIQKVEWTDDGWPVVVGGHGGQRVVEAPQDAIETEAPADHSQHDDFEVP
                     QLALDWNTLRVPFDESMGSVGGGTLTLRGQGSLCNLFDLSLVARRWQAFDFDASVGVRF
                     DPTNYRQMAGLTNYYNDLCWSWAFVTWDEKRQCRVIEVAQNDFNTYTSFLRDRAVPVPD
                     DVETVWLRTRVRTQTYGYDYSFDGEQWHDLGVELDAKILSDDYVNQRYGGFFTGAFVGL
                     AAVDLSGYDATAEFVDFDYRELSE"
     gene            9998..12028
                     /locus_tag="CNCMI4602_0523"
     CDS             9998..12028
                     /locus_tag="CNCMI4602_0523"
                     /codon_start=1
                     /transl_table=11
                     /product="9-O-acetylesterase"
                     /protein_id="AYN23383.1"
                     /translation="MDARWAGRLRDGPPSVHLHICGADDMTAWKAQGTHMTLTMPKLLD
                     DGCVLQSGRPVNIWGWCTPGERVSVRIGECAGETISAADGGWQVRLDALDPGGPYAFEV
                     IGDGATVRRSCYAGEVFLCSGQSNMELSMQWVHPYYPNEFRRQDDPLLRQFKVVDRYDF
                     SGPVRDHEEASWLECAPETLGQFSAVAYFFGRMVRQWLQVPVGLLNVSLGGSPIEAWMD
                     AASLDDCPEALEELDPYLGDGVAEARSEESLSAVAGWMEELQARRIPADKLHWRHVDLP
                     ARFEDCGLPGFQGMIELRRTVVLPPYCEGAEGTLRLGAWADIDETYINGINIGGRPNQY
                     EPRDYRIPAGMLRAGANEIVVRLVCNAGSGRVTEGKAMTLQVGDEVHDVSGIWRLAVVA
                     SMDRPCPSEDFVRWRPTGLYNAMLAPCFRFPVRAALWYQGESNTGTRAAQYGKLLATMI
                     DLWRERWHDPHMPFLIVQLPGISIDCIEDGGWPLVRAGQWAVGKQVPDVKTVVTLDAGE
                     PNDLHPHDKKLVASRLFDAACALLYGGDNVQPMVKRIEERDGMLCVSYATVARQGANPV
                     PCTPLTLDGGDLGEFEFVWRDAMCAVPAPATVEGAEVCIPLPERRPDILRYAWRNNPSR
                     GLLVDGRGTPMPPFAYDLKRGAMIEPSVRAGGDVDAGTGRA"
     gene            12265..13428
                     /locus_tag="CNCMI4602_0524"
     CDS             12265..13428
                     /locus_tag="CNCMI4602_0524"
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="AYN23384.1"
                     /translation="MDPAIPLDEDCLYLNIWTPALRGSGVDAHLTGEPLPVMVWIHGGA
                     YQCGCAMEKEFDGTALARQGVVVVSVAYRLNVFGFFSHRWLQEEAEEGAPYANFGWLDQ
                     QAALRWVRRNITVFGGDPTRICIFGQSAGAASVLAQCCAPGNAGLFSRAIMQSGAGLGY
                     FNATLCSLESAQSTGARLMRRLGVENLDEARAVDAQTLFEGASRLEAPEGVDHAAWPMM
                     VNWVPCVDGVFMPRQERDLILDGQTKNIDLVVGDTQDEFMVSDGQGHQVRAGREGNRRL
                     IAAWQHGGGRAPYYYHFDVPMPGDDAGSFHSSDLWFVFGTLGSCWRPMRGCHVELSQCM
                     SRYWTRFAAIGDPSGPGLVHWDRTDMHGDRFLHLGFPVEMRSGHRGA"
     gene            complement(13441..15000)
                     /locus_tag="CNCMI4602_0525"
     CDS             complement(13441..15000)
                     /locus_tag="CNCMI4602_0525"
                     /codon_start=1
                     /transl_table=11
                     /product="GH43_10"
                     /protein_id="AYN23385.1"
                     /translation="MNVVQNPILNSDFPDPDIIRVGHTYYMASTTMHFMPGCDILRSFD
                     LTHWEPYGHVYHTLGHTGTYMLDDDQDLYGQGMWAPSLRWHNGRFHVLFSANDTHTTHL
                     FTAEDARGPWRHHIVQGFYHDPSLLFDDGRVFIVHGNTALRLTEMEADLSGPKAGGLDR
                     VLVQDLPNQDLGYEGSHLQRHDGRYYLFTCHFARGHRKTEDCFIADSLDGEFRGRCILD
                     DDLGYHDQGVAQGGMVDTPDGQWYAFMFQDRGALGRTPVLMPMHFDTDGMPVLGVNGRV
                     PAYVESAPSAEPHHHYAPLNGDDDFRYTPDSRGTIHLAPYWQFNHTPHDETWSVTARPG
                     AFRITTSRVSATMLRATNTLTQRTTGPRCAAEVTIDASGLMEGDIAGLCAFQGCYAYAA
                     ITRRQGSWHAIMAERNALHPDNTAERHYDEVPVEVESLPLPSPQVTFRLEIDYTDMRDT
                     ARFLVRTDAGWIPIGHPHRLWFKLDHFTGCRFALFTQATQHVGGHADFMRFRYHDATDM
                     GA"
     gene            complement(15090..16619)
                     /locus_tag="CNCMI4602_0526"
     CDS             complement(15090..16619)
                     /locus_tag="CNCMI4602_0526"
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="AYN23386.1"
                     /translation="MEPMLVAGVDTSTQSCKVRVTDARTGKLVRFGQAKHPDGSTVNPQ
                     AWWEAFLEASEQAGGLDDVSAIAVGGQQHGMVILDEQGRVIRDAMLWNDISSAPQAVEL
                     IDELGAAPAADGEPEDRHARGISRWVRAVGSSPVASYTLTKLRWVSEHEPKHAERIAAV
                     CLPHDWLSWRIAGFGPVEPGEDAHLDALFTDRSDASGTLYFDAASNTYRRDLLARGLQS
                     AAADEPAPECLQAAARIVLPAVLGPHEAAKVKASPSIAGGAVDGGCIIAPGGGDNAMAA
                     LGLGMAVGDVSVSLGTSGVAAAVSERPVYDLNGSVSGFADCTGHFLPLACTINASRILD
                     AGRAVLDVDYEELTDLALAARPGAGGITLVPYFDGERTPNRPDATATLSGMTLRNTNRA
                     NFARAFVEGLLCSQRDCLELIRSLGAAIERILLIGGGAKSRAVRTLAPTVLGMEITCPA
                     TDEYVAIGAARQAAWVLSGVDDAPDWPISIDAVQTGTPTPQIYEAYVQARG"
ORIGIN
        1 atggcaggtc tgtgggacat cgacaagatc gagtatgtcg gccgcaccaa gggtcttcag
       61 gagggactcg gattccagta ttacgatgcc gacaaggttg tcgccggcaa gaagatgaag
      121 gactggctgc gcttcggtgt ggcatggtgg cacaccttcg acgcgccgct caccgacccc
      181 ttcggcgatg gcaccgccca gcgcccgtgg gacggcaagt actccgaccc gatggacaac
      241 gcgctcgcca aggtggacta cgcgttcgag ttcttcacca agctcggcgc cgagtacttc
      301 tgcttccatg accgcgacat cgccccggaa ggcgatacgc tgcgtgagac gaacgccaac
      361 ctcgaccgcg tggtcgacaa gatcgaagag aacatgcagt ccaccggcgt gaagctgctg
      421 tggaacacct cgtcgctctt caccaacccg cgcttcgtgg caggcgcctc cacctcgccg
      481 ttcgccgacg tctacgccta tgccgcggcg cagctcaagc actccctcga gatcggcaag
      541 cgcctgggcg ccgagaacta cgtgttctgg ggcggccgcg aaggctacga gaacctgtgg
      601 gtcaccgaca tgaagcgtga gcaggagcac atggcgaagt tcttccacat gtgcgccgac
      661 tacgccaagc agatcggcat ggacgcccag ttcctcatcg agccgaaggc caaggaaccg
      721 acgacgcacc agtacgactt cgacgcggct acggcatgca acttcctgcg cgcctatgac
      781 ctgatcgacg tcttcaagct caacctcgaa ggcaaccacg ccaacctcgc aggccacacc
      841 taccagcacg agatccgcgt cgcccgcgac aacggcgtgc tcggttcgct cgacgccaac
      901 cagggcgaca tgctgctcgg ctgggacctc gatgagttcc cgaccaacct gtacgagacc
      961 acctccgtga tgtgggaagt gctcgacgaa ggccagatcg gccctcacgg cggcctcaac
     1021 ttcgacgcca agccgcgccg cacctcgttc agcgctgaag acctgttccg cgcgcacatc
     1081 gccggcatgg acacgtttgc cgccggcctg ctcgtggcgg acaagatgca tcaggacaag
     1141 tacatcgagg accttgtggc caaccgttat ggctcctacg attcgggcat cggcaagtcg
     1201 atcgacgacg gcaccgccac cctcgagtcg ctcaatgact acgccatcga catgccgcag
     1261 tccgagatca tcgcatccac gcaccccgat cacctcgagg acgtgaaggc gaccatcaac
     1321 aactacatca tcgacgccct ggccaacgcc tgacgccgca cggtccggcc acctgccgca
     1381 tgggcggccg gaccgtccat ccaacctctg cggcgcgtgg catatgcagt gcacgctgta
     1441 tggcatatgc cgccagtaac tctttctttc cttccttcca atgaatcgcc gcctgttctt
     1501 tcctttcctc tgcaggcgcg atgcaggccc aagggccacc gggccccacc gtgcacccat
     1561 acgctccgcg cgcatccttc ccatcaaaca caccgcgcgc ggggagcacg gcggttcccg
     1621 gaggcccatg ggctttttcc atacgggtgg gcacgacggt gtgttcgcct attgcttgcg
     1681 caaggcgcat ggcgcaccgc tgcaccgccc ttataccctc cggccatgct gccgaaccga
     1741 atgtactgat atgaccgacc actaccgata tggaggacca cgatgaccgc aacgaccgcg
     1801 accatagaca tcaccaatcc cgtactgcgg ggcatgtacc ccgacccaag ctggatgtgg
     1861 gacgagcgcg gggagcgcgt ggccctggtg aattcctcgt tcgaactggt gccgggactg
     1921 ccgatccacg tttcagacga tatcgcgaac tgggagcttg cggggaacgc cgtcgacgag
     1981 gcgatggcgc aacggctgct gatccccttc gtgcttgatt ctgggggatt gtatgcgccg
     2041 acattgcgca tgatccgcgg gaagtacgtg atcgcatgca cggtcgcccg catcgatctg
     2101 gacgcggccg ccgcagctgg ggtcgacccg gagtcgatcg aggcggcccg cgcaagccag
     2161 ggcaacttca tcatcgaagc cgatgcgctt gaggggccat ggcgcggccc gtactggatc
     2221 gagggcgccg agggcatcga tccagacatc ttcgaggacc ttgacggctc tgtgtactgg
     2281 acgcagacaa ggccggccgt acgcccgcgc tgggaagggc agaccgaggt gtggacccag
     2341 cggatcgacc cggagacgtg gcggctgtgc gcgtcgcatg acgcagacgg cgactatggc
     2401 aagacggtcc tctggacggg atacggcgtg gaggcggtgt gggccgaagg accgcacctg
     2461 taccgcatcg gcgattgggt gtatctgatg accgcagaag gcggcacaag cttcgaccac
     2521 agcgagatga ccatgcgcac gtgggcaccc gacgggctcg gaccggcgat cgaatccctg
     2581 cagggccaag cgcacgcaga cgggaccgag ccgcgcgcgc cacgtgccga cgaacggtcg
     2641 gttgtggggc ggtatgcgcg actgttccat ccgtgcaaga agaatccgtt cctgacacac
     2701 cggcatcttg gtttggagga gcgcgtgcag tgtgtgggcc acgccgatct gctgcatcat
     2761 ccgcggcttg gctggtgggc cgcgtgcctg ggctcgcgcg agacccccac cgcggaccat
     2821 ggggcgctca gcttcctagg cagggagacc tttgtggcac ctgtcgactg gcagcacgat
     2881 ccggcacaat ggtcgctgga atccaatggg cccgcgcaaa ggcggactga tgacccgggc
     2941 tggccgatac tcgccggggg agcggggcgt ctggcgcaga cattgcgcat cgatgcggcg
     3001 gacgggaccc tgctcgatat gtgcattggt ccgtgcgaat cgcaggctgt cgtcgatgcg
     3061 cgcatgcctt ttgccgtcgg cgacggcgaa ggcgcggccg tgcgcgcgga tggcacggtg
     3121 taccggcgta tgccggaaga caggtgcgtg gtgctgtgcc cgccgcgtgg cacggtgcgt
     3181 atccggcagg acggccgcca tacgttgagc gtggcgaccg atagtgcgtc ggtgcagtgg
     3241 gcgctcggcg agggtacgga gcgcagggaa ggcatggtgc cgatccccga gggggagccg
     3301 ggatcggtta tgctcgtctt cgacaaaggc atggcgcgtg tggtcgtggc gcagtccgcg
     3361 gaacaggcat ggacggcgcc ggccgtcgag gtgatcgacg tggcgccgct gagcaccgaa
     3421 tggtccggcg gcttcgtggg gtgcctcgtc ggttgtgacg cgtaggcggc gacctaagcg
     3481 ggatggttgg gccactgttg cggtagcctt ggccggctcg ccgtgcacca gccgctgccg
     3541 tttgcgcagc agcatcgcga aattgcggag caccggtatg agcagtcctc cgcataccat
     3601 gccgatgtcg gaggcgcgct ggtccgccat cagcgcgcct ccgacgccaa gcgggccgtg
     3661 ctgccgcgca cgacgagcgt cgtcgggagg atcacatggt gttgcgtggg gcgcccctcc
     3721 gccgtgtcga tgagcatgcg cgtcgagacc gccgccatgt cgtgcaatgg ctggcgcacc
     3781 gtggtgagcg ccggacctag gaacgcggag gtctgcacgt cgtcgaaacc gacaaccgaa
     3841 aggtcttcgg ggatgcgcag ccggttctgc cgggcggcct catagacgcc catcgcctgc
     3901 aggtcgctgc cagcgaagat cgcggtgggg cggttcgggt tctccagcaa cgccatcgcc
     3961 tgcgcgtagc cgccttcggt cgtgaaatcg ccttcggtca ccagctcggg atccagcgcg
     4021 atgccctgtt cggcgagcgc cgacgtgtag ccgtcgagcc gcgcacgcga gcacatcatc
     4081 tcttcggggc cggtgatgat gccgatgcgc gtgtgcccca gggcgagcag atgccgagtc
     4141 gcgagcacgc cgccggccca gttgtccgcc tgcacggaga aatcatcgtt cgacggctcg
     4201 cccgaagggt cgaagatgac ataggggatg ccgttggcct gcaatttggt tttttctttt
     4261 tcggtgagat tggcgaagat gaagatgacg ccgaatggcc tgcgcctcag catgccggtg
     4321 atccagtcgt cgtcggggtg ttggcgggtg ccactttccg tcgtgatgac gctgatgtcg
     4381 ggcgagtgcc ttgtctcacg cagcacgccg cgcagcactt cgagagccca gattgtgtcg
     4441 aggtcctgaa agaccacttc gatgtacctt tggccggccg ctttctggcc gcggcgctgg
     4501 tagcccgagg ccttgagtgc ctgatcgatg gctgtgcggg cctcgtcgga gatgtcggac
     4561 cttccgttga gtgccttgga gacggttgcc aacgagtagc cggtgtgctt tgcgatgtcc
     4621 gccaatctga ctttggattc cgacatatgg agctcctttg ccgcaaatga atgggggtga
     4681 tatcatctgt cataatatcg aaagtttcgt aatgttgcaa gcgaaatatg cgcttgttgt
     4741 gaaaacggcg agcaaatgta tacaaaagtg cgcgaaacgc cgaaaataca ctttgtttga
     4801 ctaattgaca aagtaggttt acgatagttt ctaacgaaaa cagcgtaagt tttcggaagt
     4861 tctcaatgtt gtaccggagg cttcgtagaa gctcggatgc attgctcttc tggcaatgcg
     4921 cgtcagcgag gacggctcca cgtcaatgtc agcgtggaca aagatcaagg aggaactatg
     4981 aaactcaaga cgcttgcagc agcaacactg gccgttgcga ccgtactcgg catgagcgca
     5041 tgtggtgggt cggggtcgtc gtccgatgac aagaccatca cgttctggca caatgcttcc
     5101 gccggtaaag gacgccagta ctgggagaat ctggcaaagt ccttcgaaga ggccaacccg
     5161 gggaccaagg tggagatcca ggccattcag aacgaggact tcgccggcaa gctgcagacc
     5221 gccatgcagg atcccgcatc cggtccggat gtcttcatgt cgcttggcgg ctccaagacc
     5281 caggaaatga tcgacgccgg ccaggtcatg gacctgaccg ataagatctc ggacacggtg
     5341 aagaccgata tgaagtcgac cctttctgct gccacgttcg acggcaaggt ctacggcgtc
     5401 ccggtcagtg tggaaccggg cggcatgtgg tattccaagg atctgttcaa gaaggcgggc
     5461 atttccggtg tgccggcgac ctacgaggac ctgctcgcgg acgcgaagaa gctcaaggac
     5521 agcggcaccg atgccatcgc gctcggcgcc aaggacgctt ggcccgcggc gcattggtat
     5581 tactggctgg tcctgcgcga atgctctcct gcagtctacg acaagagcgt tcaggaccac
     5641 gacttctcga acgcgtgctg ggtcaacgcc ggcaagaagc tgcaggagct caaagacttg
     5701 aaggtcttca acgacggctt cctgaccacg accgcgcagc agggcgccaa ctcctctgcg
     5761 ggcctgcttg ccaaccataa agcggccatg gaactcatgg gcgcttggga gccgggcgtg
     5821 ctcggtgatc tcacccccga tcagaagccg atggctgacc ttggattctt cgcgttccct
     5881 gaggttgcag gcggcgaagg cgagcccggt gcgctcatgg gcggcgtgac ctacttctgt
     5941 gtcaacccga aggcttcaca ggcctcgatc gatttcgtca actacatggg tgagaagaag
     6001 aaccaggagg attacgccga ggcgttctcc accatccctg cctccgagcc cgcgcgtggt
     6061 gtggtgaccg acgagtctct caagcaagtc atcgaatacc tggacaaggc tccgtccatg
     6121 cagctgtgga tggataccgc actgggcacc aacatcggca acgcgttgaa tgccgctgtg
     6181 gtgaacatgc tgtcggggca gggtagcccc gaagacatcg tcaaggcgat ggaggacgcc
     6241 gcccagaagg gctgattgcg tctgagcaag gtccgggatg gctgggctat gcctcatggt
     6301 ccagccatcc tttcccctgg atgacgtata acgaaacacc ttagatacat gggattgatg
     6361 acatgactga aatgaatgat gccgtggcag tcgggcgacc ggttgccgaa acgaagaagc
     6421 ggggcggaga acgcaaaccc tctaacggca aggggcgcag aaatctcgaa attttcatcc
     6481 tttccgcacc cgcgattatc ctcttctgct gctttgtgat ttttccgatc attttgggcg
     6541 cctactacgg cttctaccag tggaagggct ttggcactcc ggccgagaac ggcaagttcg
     6601 tcggactgca gaactacatc gtggcgttga aggatccgaa cttccaacag gcgatcctgc
     6661 acacctttga aatcgtcatt gggtccctcg ttatccaggg gccgttggcc atcctcttcg
     6721 ctctcctgct caaccagaag ttcaagggac gtggcctgat ccgtacgctc atcttcgtgc
     6781 cgtatgtcgt ttcggaagtc atcgtcggca ccggctggag cctgctactc cagaagaagg
     6841 gcgcggtcaa ccagatcctt gaatcactcg gcatgcatgg tgtcgattgg ctcgctgatc
     6901 ccaaggtcgc gatctggacg ctgctgttgc tcatcagctg gaaatacatc ggattcgccg
     6961 tcatcctcat gcttgcaggc atgcagtcga ttcctgagga actgtacgaa gcggcaaagg
     7021 tggacggtgc agggttctgg cagatccaga agagcatcac actgccgttg ctcgccccga
     7081 cgctgcgcat ctgggtcttc ctgtcgatga tcggttcgct gcagctgttc gatttggtct
     7141 acatcatctg gggccagtac gtttccacga cggccggcgt ctccacaatg gccacctaca
     7201 tggtccgcga gggacgcggt gctggcaact acggatatgg ttccgccgtc gccctcatca
     7261 ttttcgtcat ctcgctgatt gtggcgctga cctaccagca ctttgtgctc aaccgtgatc
     7321 tcgatggcgc cttgaccgag aagaaggcgt ccaagaagcg caggaagagg cagaccgcag
     7381 aagatgaggc cctggcggtc gccatggaag gagtgaagtg agatgagtgc tgcaacggca
     7441 tattccaaga aaaacggttt ccacaagtcc gcgaagaccc catggggcaa cccgatagtc
     7501 tatttcttct cgcttgtgct cgtggcgatt tgtatcgtcc cggtgcttta catcatcttc
     7561 ggcggattcc gtaccaacgc gcagatcacc aacaaccctg ccggtctgcc gaatccctgg
     7621 gtgatcagca actacaagga cgtcatcacc agtgatatgt tctggaccga gctgggcaac
     7681 tcgctgatcg ctggcatctg cacgatggtc ggcgtcgtcg tcctcggcat catggtcagc
     7741 tacgtcatcg cccgctacaa gttccggtac tcggcactga tgtatgcgct gttctcggcg
     7801 ggcctcatgt tcccgatgac cgtcggtatc actccgctgt acctgatgat caggaatctg
     7861 ggtctgtcga actcccttgc gggcattatc cttccgggaa ttgctttcgg tctgccgcag
     7921 accatcatca tcctggtccc cttcctgcaa tccatcccga tggaattgga ggaggcgtgc
     7981 ctgctggacg gttgttctcg cctcggcttc ttctggcgca tggtcatccc gctgtcgatg
     8041 cccggcgtcg ccacaaccgg catcctcacc ttcgtgggaa gctggaacgg ctatatgctt
     8101 ccgctcttcg tcctgagcga tgaaagcaag tacacgcttc cgcttggtgt gcagatgttc
     8161 agctcccagc actcggtgga tacggccagg gtcctggcgt tcacctcgct cgccatgctt
     8221 ccggccctca tctgcttcac gatcttccag aagaagatcg tgggtggcct gaccggcgcg
     8281 gtcaagggct gatctgaccc gccgcctgca atgcacgaag cgcggcggcc cggtcacaac
     8341 cgggccgccg tttccttaag gagatcgtta tgaagatcga aaacccggta ctgcccggat
     8401 tcaacgccga tccgtcgatg atcagggtcg gagacaccta ctacatcgcg aattccacgt
     8461 tcgaatggtg gcctggcgtg cgtctgcacg agtcgaagga catggtgcat tggcgcctgt
     8521 tgccgagccc gctgaaccgt cgttcgcaga tcgacatgcg cggcaacccg tcctccggtg
     8581 gcgtgtgggc tcccgacctg tcctatgcgg acggcaagtt ctggctcgtg tactccgatg
     8641 ttaaaatcgt caacggcgcg ttcaaggact gcacgaacta cctcgtgacc gccgaggaca
     8701 tccgtggccc gtggagcgaa ccgatccgga tcaacggcgt tggcttcgat gcaagcctgt
     8761 tccatgacga tgacgggcgc aagtacctcg tccagcagac ttgggatttc cgtgaataca
     8821 accatccctt cgatggcatc acgcttaccg agttcgacgt cgagaccatg cgcctgcgcc
     8881 ctgagaccga acgcacgatt tggcgcggca ccgatgtcaa actcgtcgaa ggcccacacc
     8941 tgtacaaaat caacggcatg tactacctgt tctgtgccga gggcggcacc gtctggacgc
     9001 atcaggaggt cgtcgcgcgt tccgcgacgc tcgatgcgat gtcgttcgag gggagcccgt
     9061 acaacccgtt catcagcaac ttcgacaccc cacgcagcta cctgcagaag caggggcatg
     9121 gcgcactcgt ggatacgcca tccggcgaat ggtactacgc gtcgctgtgt ggccggccct
     9181 ggcaccatga gaacgaatcg gtgaccgatc cgcgtggatg gtgcaccctg ggccgcgaga
     9241 cgtccatcca gaaagtcgaa tggaccgatg acggctggcc tgtcgtcgtc ggcggtcatg
     9301 gcggacaacg cgtcgtcgag gcgccgcaag acgccatcga gaccgaggca ccggccgatc
     9361 acagccagca tgacgatttc gaggtgccgc agctcgccct ggattggaac acgctgcgtg
     9421 ttcccttcga cgaatcgatg ggttccgtcg gaggcggcac gctgaccttg cgtgggcagg
     9481 gatcgctgtg caacctcttc gacctgtccc tcgtcgcccg ccgttggcag gcgttcgatt
     9541 tcgacgcgtc tgtcggtgtg cgattcgacc ccaccaacta ccggcagatg gccggtctga
     9601 cgaactacta caacgacctg tgctggtcgt gggctttcgt cacttgggat gagaagcggc
     9661 agtgccgtgt gatcgaagtc gcccagaacg atttcaacac ctacacctcg ttcctgcggg
     9721 accgggcggt accggttccc gatgatgtgg agaccgtatg gctgcgcacg cgtgtgcgca
     9781 cgcagaccta tggttacgac tattcgttcg acggtgagca gtggcatgac ctcggtgtcg
     9841 aactggacgc gaagatcctg tcggacgact atgtgaatca acggtatggc gggttcttca
     9901 ccggagcgtt cgttgggctc gcggcagtgg acctgtcggg gtatgacgca acggcggagt
     9961 tcgtggactt cgattaccgc gaattgagtg aatgaccatg gatgcacgct gggcgggccg
    10021 tctccgagac gggccgccca gcgtgcatct ccatatctgc ggtgcagatg acatgaccgc
    10081 atggaaggcg caagggacgc atatgacatt gacaatgcca aagctgctgg atgatggatg
    10141 tgtgctgcaa tccggcagac ccgtgaacat ctggggatgg tgcacaccgg gggagcgtgt
    10201 ctccgtacgt atcggcgaat gtgcagggga aaccataagc gccgcggacg gcggctggca
    10261 ggtgcggttg gatgcgttgg atcctggcgg cccgtatgcc ttcgaagtga ttggcgatgg
    10321 cgcgacagta cggcgctcat gctatgcggg tgaggtgttc ctgtgttcgg ggcaatccaa
    10381 tatggagctt tccatgcaat gggtacatcc atactatccc aacgagtttc ggcggcagga
    10441 tgaccccttg ctgcgccagt tcaaggtcgt ggaccgatac gatttctccg gcccggtgcg
    10501 tgaccatgag gaggcctcat ggctggagtg tgcacccgag acgctgggcc aattctccgc
    10561 agtcgcgtat ttctttgggc gaatggtgcg ccagtggttg caggtccccg tcggactgct
    10621 caatgtatcg ttgggcggtt cccccatcga agcatggatg gacgccgctt cactcgatga
    10681 ttgtcctgaa gcgttggagg agctggatcc ctatctgggt gatggcgtgg ccgaggcgcg
    10741 gagcgaagag agtctgtccg cggtcgctgg atggatggaa gagctgcaag cgcggcggat
    10801 tcctgccgac aagctgcatt ggcgccatgt cgacctgccg gcccgttttg aggattgcgg
    10861 gttgccggga ttccagggaa tgatcgaatt gcggcggaca gtggtgctgc cgccctattg
    10921 cgagggtgct gaaggcacgc tgcggttggg ggcatgggct gacatcgatg agacctacat
    10981 caatggaatc aacatagggg gccgccccaa ccaatatgag ccccgtgact accggattcc
    11041 tgccggtatg ctgcgcgcgg gggccaacga gattgttgtg cgccttgtct gcaacgcggg
    11101 atccggccgg gtgaccgaag gcaaggcgat gaccttgcag gtcggcgatg aggtccatga
    11161 tgtgagcggc atctggaggc ttgccgtcgt ggcgagcatg gacaggccat gtccgagtga
    11221 ggattttgtg cgttggcgcc ccaccgggtt gtataacgcc atgctcgcgc cttgcttccg
    11281 tttcccggta cgcgctgcgc tgtggtacca aggggaatcg aacaccggga ccagggcggc
    11341 gcaatacggc aaactgctcg ccacgatgat cgatctgtgg cgggagcgtt ggcatgatcc
    11401 gcatatgccc ttcctcatcg tgcaattgcc cggcatcagc atcgattgca tcgaggacgg
    11461 cggttggccg ctcgtacgcg ccgggcagtg ggccgttggg aagcaagtac ccgacgtgaa
    11521 gacggtcgtg acgctggatg ccggtgaacc caacgacttg catccgcatg acaagaagct
    11581 cgtcgcgtca cgtctgttcg acgcggcatg tgcgctgctc tatggaggcg acaatgtgca
    11641 gccgatggtg aagaggatcg aggaacgcga tgggatgctg tgcgtctcct atgccactgt
    11701 tgcccgccaa ggggccaatc cggtcccttg cacgccgttg acgctcgatg gcggcgatct
    11761 gggtgaattc gagttcgtct ggcgcgatgc catgtgcgcg gtgcctgcac ctgcgacggt
    11821 tgagggggca gaagtgtgca ttccgctgcc tgagcggcgt cccgacatac tgcggtatgc
    11881 atggcggaac aacccgtcac gtggtctgct tgtggatggc cggggcactc cgatgcctcc
    11941 atttgcctat gatttgaagc gtggtgccat gatcgagcca tcggtgcgcg ctggcggaga
    12001 cgtcgatgcc gggacgggac gtgcgtgatg cgcaggcaag tcacatgtga gcagggaaca
    12061 ctcgagggat tggcggtggg tgatccctcc atcacagctt ttcgtggagt gccgttcgcc
    12121 gctccaccag tggggccgct gcgttggcga ccaccccagt cgccggcgcc ttggcaaggt
    12181 gtacggtgtg cgttcgacga tgccccggcc tgcctgcaac ccattccggg agcgtcaaac
    12241 ccgttctatg acaaggaatg gggcatggat cccgccatcc cgctcgatga ggattgcctg
    12301 tatctgaaca tttggacgcc ggcattgcgg gggagcggcg tcgatgcgca cctcaccggc
    12361 gaacccctgc cggtcatggt gtggatccat ggaggcgcct accagtgcgg gtgcgcgatg
    12421 gagaaggagt tcgacggcac cgcgctcgcg cgtcagggcg ttgtggttgt gtcggtggcg
    12481 tatcggctga acgtgttcgg atttttctca caccgctggc tgcaggagga agcggaggaa
    12541 ggcgccccgt atgcgaattt cggatggttg gaccaacagg ccgcccttcg gtgggtgcgc
    12601 cgcaacatca ccgttttcgg tggcgacccc acacgcatat gcatcttcgg gcagtccgcg
    12661 ggtgcggctt cggtattggc gcaatgctgc gcgccgggta atgccggact gttctcccgg
    12721 gcgatcatgc aatcaggtgc gggccttggc tacttcaatg caacgctgtg ctcattggaa
    12781 tccgcacagt cgacgggcgc aaggttgatg cggcgtctgg gggtggagaa cctcgatgag
    12841 gcacgggctg tcgatgcgca gaccctgttc gagggagcat ctaggcttga ggcgcctgaa
    12901 ggtgtggatc atgccgcatg gccgatgatg gtcaattggg tgccatgtgt cgatggcgtc
    12961 ttcatgccac ggcaggagcg cgatctgata cttgacggcc aaaccaagaa catcgatctg
    13021 gtggtgggtg atacgcaaga cgaattcatg gtgtccgacg ggcaaggcca tcaggtgcgg
    13081 gctggccgcg aaggcaaccg ccggctgatc gcagcatggc agcatggtgg cggccgcgca
    13141 ccgtattatt accatttcga tgtgccgatg cccggcgatg acgcgggctc cttccattct
    13201 tccgacctct ggttcgtgtt cgggaccttg ggctcatgct ggcgacccat gcgtggatgc
    13261 catgttgagc tctcccaatg catgtcacgg tattggacgc gttttgcggc gataggcgat
    13321 cccagtggac cgggtcttgt gcactgggac cgcaccgaca tgcatggcga ccgcttcctg
    13381 catctgggtt tccctgtgga aatgcgcagt gggcatcgcg gcgcatgact acaccttggg
    13441 tcaagctccc atatctgtgg catcgtgata acggaagcgc atgaagtcgg catgtcctcc
    13501 aacatgctgg gtcgcttggg tgaacagtgc gaaccggcat cctgtgaaat gatccagttt
    13561 gaaccacagg cggtggggat gtccgatcgg tatccacccg gcgtctgtcc gcacaaggaa
    13621 acgcgcggta tcgcgcatgt cggtgtagtc gatctccaaa cggaacgtga cctgcggtga
    13681 cggcaatggc agggactcca cttcaaccgg gacctcgtcg taatggcgct cggcggtgtt
    13741 gtccggatgc agcgcattgc gttccgccat gatcgcatgc caagatccct gcctgcgtgt
    13801 tatggcggcg tatgcgtagc agccttggaa tgcgcagagc ccggcgatgt cgccttccat
    13861 gagtccgctg gcgtcgatgg tcacttccgc ggcgcaccgt gggccggtcg tgcgttgcgt
    13921 aagcgtattg gtcgcccgca gcatggtggc cgatacgcgg cttgtggtga tgcggaatgc
    13981 accggggcgc gcggtcaccg accatgtctc gtcatgtggt gtgtggttga actgccaata
    14041 gggggccaga tggatggttc ccctgctatc gggcgtgtag cggaaatcgt catcgccgtt
    14101 gagcggcgca taatgatggt gcggttcggc ggaaggcgcg ctttcgacgt atgccggaac
    14161 tcgcccattc acgcccaata cgggcatgcc gtccgtatcg aaatgcatcg gcatgagcac
    14221 gggtgtcctg cccaatgccc cgcggtcctg gaacatgaac gcgtaccatt ggccatcggg
    14281 cgtgtccacc atgccacctt gcgccacacc ttggtcatgg tatcccaagt cgtcgtccag
    14341 aatgcagcgg ccccggaact caccgtcaag cgaatccgcg atgaaacaat cctcggtttt
    14401 gcggtggcca cgggcgaaat gacaggtgaa caggtaatac cgcccatcat gccgttgcag
    14461 atgggatccc tcgtatccca gatcctgatt cggcaaatcc tgcacgagca cacggtcgag
    14521 tccaccggcc ttcggtccgg acagatccgc ctccatctcg gtcagccgca gtgcagtgtt
    14581 gccgtgaacg atgaacacac gcccatcgtc aaagagcagc gaaggatcgt ggtagaagcc
    14641 ctggacgata tgatgacgcc atggaccgcg ggcgtcctca gcggtgaaca gatgggtcgt
    14701 atgggtgtca ttcgcggaga acaacacatg gaatctgcca ttgtgccatc gcagggacgg
    14761 cgcccacatt ccctgcccat acaggtcctg atcgtcgtct agcatatagg tgcccgtgtg
    14821 cccaagtgtg tggtagacat ggccatacgg ttcccaatgt gtcaggtcga acgacctcaa
    14881 tatgtcgcat ccgggcatga aatgcatcgt ggtgctcgcc atgtaatagg tatggccgac
    14941 cctgatgatg tcgggatcgg gaaagtccga gttgagtatt ggattctgga cgacgttcat
    15001 gaaactcctt ggaatcggaa tcgacaatat ggaatgccgg gtggtgggca caatgtgcgc
    15061 atggtgcaca ccacccggcc tgggtggaat cagccgcggg cctgcacgta ggcctcgtag
    15121 atctgcgggg tgggggtacc ggtctgcacc gcgtcgatcg aaattggcca gtcgggcgcg
    15181 tcatctacgc cgctgagcac ccaagccgcc tgtcgtgcgg ctccgatggc cacgtattcg
    15241 tcggtggcgg ggcaagtgat ttccatgccg agcacagttg gggccaacgt gcgcaccgca
    15301 cgcgatttcg ctccgccgcc gatgagtagg atgcgctcaa tcgcggcgcc gagcgagcgg
    15361 atgagctcca gacagtctcg ttgtgagcac agcaacccct cgacgaatgc gcgggcgaag
    15421 ttcgcgcgat tggtgttgcg tagcgtcatc ccgctgaggg tggcagtggc gtccggtcgg
    15481 ttcggtgtgc gttcgccgtc gaaatacggc accaatgtga tgccgccggc accggggcgc
    15541 gcggctaggg cgaggtcggt gagctcctcg tagtccacgt cgagcaccgc acgtcctgcg
    15601 tcgagaatgc gggaggcgtt gatggtacag gccaggggca ggaaatgccc ggtgcaatcc
    15661 gcgaatccgg aaacagagcc gttcagatcg tatacagggc gctcgctcac agccgcagcg
    15721 acacccgatg tgccaaggga cactgacaca tctccgacgg ccattcccaa gcccagggct
    15781 gccattgcat tgtcgcctcc gccgggggcg atgatgcagc ccccgtctac ggcgcctccg
    15841 gcaatcgatg gggaggcttt caccttggcg gcctcgtggg ggcccagcac ggcgggcagc
    15901 acgatgcgtg cggcggcctg gaggcattcg ggggccggtt cgtccgctgc ggccgattgc
    15961 aagcctcggg cgagcagatc gcgccggtag gtgttggacg ccgcatcgaa atacaaggtg
    16021 ccggaggcgt cggaacggtc ggtgaacagt gcgtccaaat gggcatcctc gccaggctcc
    16081 accggtccga aaccggctat gcgccagctc agccagtcgt ggggcaggca gacggcggct
    16141 atgcgctctg catgcttcgg ctcgtgctcg ctcacccacc gcagcttcgt caacgtgtat
    16201 gaggcgacgg gggaggagcc caccgcacga acccagcggg agatgccgcg ggcgtggcga
    16261 tcctccggtt caccgtcggc cgccggtgcc gcgccgagtt catcgatgag ttcaacggcc
    16321 tgaggggccg acgagatgtc gttccacagc atcgcatcgc ggatcacgcg cccttgctcg
    16381 tcgaggatca ccatgccatg ttgttggccg ccgacggcaa ttgccgagac gtcgtccaat
    16441 ccgccggcct gctcactggc ttcgaggaac gcctcccacc aggcctgggg attcactgtc
    16501 gatccgtccg ggtgctttgc ctggccgaag cgtacgagct tacctgtccg ggcatcggtg
    16561 acgcgcacct tgcatgattg ggtcgaagtg tcgacgcccg caaccaacat cggttccat
//
