LOCUS       CP000139               15265 bp    DNA     linear   BCT 31-JAN-2014
DEFINITION  Bacteroides vulgatus ATCC 8482, complete genome.
ACCESSION   CP000139
VERSION     CP000139.1
DBLINK      BioProject: PRJNA13378
            BioSample: SAMN02604309
KEYWORDS    .
SOURCE      Bacteroides vulgatus ATCC 8482
  ORGANISM  Bacteroides vulgatus ATCC 8482
            Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
            Bacteroides.
REFERENCE   1  (bases 1 to 15265)
  AUTHORS   Xu,J., Mahowald,M.A., Ley,R.E., Lozupone,C.A., Hamady,M.,
            Martens,E.C., Henrissat,B., Coutinho,P.M., Minx,P., Latreille,P.,
            Cordum,H., Van Brunt,A., Kim,K., Fulton,R.S., Fulton,L.A.,
            Clifton,S.W., Wilson,R.K., Knight,R.D. and Gordon,J.I.
  TITLE     Evolution of Symbiotic Bacteria in the Distal Human Intestine
  JOURNAL   PLoS Biol. 5 (7), E156 (2007)
   PUBMED   17579514
  REMARK    Publication Status: Available-Online prior to print
REFERENCE   2  (bases 1 to 15265)
  AUTHORS   Xu,J., Minx,P., Latreille,P., Cordum,H., Van Brunt,A., Kim,K.,
            Fulton,R., Fulton,L., Chinwalla,A., Clifton,S., Wilson,R.,
            Mahowald,M., Henrissat,B., Martens,E., Ley,R. and Gordon,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-SEP-2005) Genome Sequencing Center and Center for
            Genome Science, Washington University in St. Louis, 4444 Forest Park
            Boulevard, St. Louis, MO 63108, USA
FEATURES             Location/Qualifiers
     source          1..15265
                     /organism="Bacteroides vulgatus ATCC 8482"
                     /mol_type="genomic DNA"
                     /strain="ATCC 8482"
                     /type_material="type strain of Bacteroides vulgatus"
                     /db_xref="ATCC:8482"
                     /db_xref="taxon:435590"
     gene            complement(4..1236)
                     /locus_tag="BVU_4133"
     CDS             complement(4..1236)
                     /locus_tag="BVU_4133"
                     /codon_start=1
                     /transl_table=11
                     /product="CE9"
                     /protein_id="ABR41735.1"
                     /translation="MKKLLFLLANLICQLKILTYHSIMLTQIINAKILTPQGWLKDGSV
                     LMRDNKILEVTNCDLAVIGAELIDAKGMYVVPGGVEIHCHGGGGGDFMEGTEEAFRTAI
                     NAHMKHGTTSIFPTLSSSTVPMIEAAAETCTRLMAEPDSPVLGLHLEGHYLNMKMAGGQ
                     MPENIKDPDPKEYIPIVEKWGCIKRWDAAPELPGAMQFGKYITGKGILASVAHTQAEYE
                     DIRAAWESGYSHATHFYNAMPGFHKRREYKYEGTVESIYLIDDMTVEVVADGIHVPPTI
                     LRLIYKIKGVERACVITDALACAASESNVAFDPRVIIEDGVCKLADRSALAGSVATMDR
                     LIRTLVQKAEIPLEDAVRMASETPSRIMGVYDRKGSLQKGKDADILILDQDLNIRAVWA
                     MGKLVEGTCTL"
     gene            complement(1343..3847)
                     /locus_tag="BVU_4134"
     CDS             complement(1343..3847)
                     /locus_tag="BVU_4134"
                     /codon_start=1
                     /transl_table=11
                     /product="GH2"
                     /protein_id="ABR41736.1"
                     /translation="MNTKRFLCAALGAVCYFAFLQAQVRTEQTFEKGWKFTREDNAEFA
                     NPGYNDSKWQNVTVPHDWAIYGPFSINNDKQEMAITQDGQTEAMEHAGRTGGLPFVGTG
                     WYRLNFDAPGFEKGKKATLIFDGAMSHARVYVNGQEAGYWPYGYNSFYVDATPYLKPGE
                     RNELAVRLENEPESSRWYPGAGLYRNVHLVINEDTHIPAWGTYVTTPVVTDKYAKVSLK
                     TSLVSPEGANKDNYRIVTQIKDKNGKVVATGENKLSVFDNALFEQEFAVANPELWSPDT
                     PVLYTAESKVYEGNTLKDEYTTRFGIRTLEIVPGKGFFLNGKLTKFKGVCNHHDLGPLG
                     GAVNDAAIRRQIRILKDMGCNAIRTSHNMPAPELVEACDEMGMMLMVESFDEWKSAKMA
                     NGYHKIFDEWVEKDLTNLIRHYRNNPSIVMWCIGNEVPDQWNGNNGPKLSRMLQDICHR
                     EDPTRPVTQGMDAPDAVVNNNMAAVMDVAGFNYRPHKYPENYKKLPQQIILGSETASTV
                     SSRGVYKFPVVRQAMKKYDDHQSSSYDVEHCGWSNLPEDDWIWHEDNAWGIGEFVWTGF
                     DYLGEPTPYYTDWPSHSSLFGIIDLAGLPKDRYYLYRSHWNKDEETLHILPHWTWPGRE
                     GEVTPIFVYTNYPSAEVFINGKSQGKRTKDLTVTAENSADSASIADFKRQKRYRLMWMD
                     TKYEPGTVKVVAYNDKGEAVAEKEIHTAGKPDHIELVTDRNEIKADGKDLSFVTVRVVD
                     KEGNLCPDAQHLIKYSVKGAGTYRAGANGDPTSLELFHVPQMKVFNGMMTAVVQSTDKP
                     GEIILTATGKGLKSGRLVLMSK"
     gene            complement(3850..6102)
                     /locus_tag="BVU_4135"
     CDS             complement(3850..6102)
                     /locus_tag="BVU_4135"
                     /note="related to an ill-defined alpha-1,2-mannosidase"
                     /codon_start=1
                     /transl_table=11
                     /product="GH92"
                     /protein_id="ABR41737.1"
                     /translation="MKKQILLSAVLACISVFSAAAQKEPVDYVNPFVGTTNYGTTNPGA
                     LTPHGMMSVTPFNVMGVPEGDKDKDKQWWSTPYEFNNKYLTGFAHVNLSGVGCPELGSL
                     LLMPTTGKLDVDYHNYGSFYQGETANPGYYTNILDKYNVKCELTATPRTSMARFTFPAG
                     QSNILLNLGEGLTNESGATVRFVNDREIEGTKLLGTFCYNPQAVFPIYFVMRINKVPAK
                     RGYWKMMRPMGVEAQWDDTAGKYKLYTAYTKEISGDDIGVWFTYDTTAEEVIEVSMGVS
                     FVSIENARLNLEKEQPFGTTFDKLRAEARKKWNDDLSRIKVEGGTEEQKGVFYTAMYHT
                     MVHPNILQDVSGQYPQMEGDKILTTNHNRYTVFSLWDTYRNYHQLMTLVYPERQMDMIH
                     TMMGIYKEHGWFPKWELYGRETLTMEGDPSIPVLVDSWMKGLQDFDIDEAYKGMYKSAT
                     TPGKDNLMRPDNDDYMSKGYVPMESQYDNSVSHALEYYVADYALSTLAEALGKKEDAKL
                     FRKRSMGYKNYYSKDFGTLRPITKEGKFYEPFDPKEGANFAPSPGFHEGNAWNYTFFVP
                     HDINGLVKLMGGDKKFVDKLQSVFDEGNYDPANEPDIAYPYLFSRFKGEEWRTQKLVKE
                     LLAKYFTTKPDGIPGNDDTGTMSAWAIFSMMGFYPDCPGVPEYTLTTPTFDKVTVQLDP
                     KYWGKKELVIKKEGQGDYIKEIRLGNKKINKYLISHDDLIKAGEITFIVTENPNKK"
     gene            complement(6129..8183)
                     /locus_tag="BVU_4136"
     CDS             complement(6129..8183)
                     /locus_tag="BVU_4136"
                     /codon_start=1
                     /transl_table=11
                     /product="GH20"
                     /protein_id="ABR41738.1"
                     /translation="MRRLIILAEVALGLLFASCTKEEQRTLSVIPAPLKVELQQEVFSL
                     NSETGLYIDASEGDKKILEDYLVASSMNLKPVIAEEGHNVVLKQVAELPEVNSSEGYVL
                     TVTPDQVLIRATSGAGLFYGVQTMLQMVDEKGLPAGVITDEPRFAYRGFMMDVSRHFFD
                     KEFIKKQMDALAYYKLNRLHLHLTDAAGWRLEIKKYPRLTEFAAWREFPTWKEWWNNGR
                     RYEEEGSKDAHGGYYTQDDIRELVAYAQERFITVIPEIEMPAHSEEVLTAYPELSCTHE
                     PYKQADFCVGNEKTFEFLENVLTEVMELFPSEYIHIGGDEAGKASWPTCKLCQARMKKE
                     GLKDVNELQSYLIHRIEVFLNAHGRKLLGWDEILEGGLAPNATVMSWRGTEGGMKAVDS
                     GHMAIMSPGEFCYFDSYQDAPDSQPEAIGGYLPLSKVYSFNPVPDTLSADKVQLVYGVQ
                     ANLFTEYIPTPEHAEMMIYPRILALAEVAWSAPSVKNYDDFHVRALKEVEALKAEGYHP
                     FELKNEIGNRPGADQPVQHLAVGKKVAYGPDAAYYPGYSAGGDSALVDGVIGGWTYGDR
                     RWQGFIDKKRMDVTIDMEKETEIHSVGADFMQVCGPEVFMPSEVIISVSNDGKEFTELK
                     RMEHKVVKDDKVTFINFGWEGNAKARYIRYQASSGEFGGFLFTDEIVVK"
     gene            complement(8180..9307)
                     /locus_tag="BVU_4137"
     CDS             complement(8180..9307)
                     /locus_tag="BVU_4137"
                     /codon_start=1
                     /transl_table=11
                     /product="conserved hypothetical protein"
                     /protein_id="ABR41739.1"
                     /translation="MIRKIIYGVYAILGMMTMAACSGQSDASEISLEKMHGFPTENTGF
                     LKGVSALYAGVIEGNLLIAGGCNFPDIPVADGGKKAYYRDIYIAPLSNDTAFEWKKIGQ
                     LPQAAAYGVTISTEKGLICVGGTTATHSLSDVFLLSLQKDTLKRDTLPSLPVTMDNMAG
                     ALVGHSLYIVGGNVNGIPSSAMYMLDLSDLSGGWKRETDIPGEPRVQSVCVAQDGKLYV
                     WGGFAPAVEGHQASLSVDGYMYSPETKEWSSVATPYDAEGNEISLGGGMGTSFGEGMIL
                     CAGGVDKDIFLKALQGIYAGKEYLSHPVEWYRFNRNLLLYHPQTDKWTTLGEYEQGARA
                     GAVIVSQDGFHYIINGELKPGIRTNEINRIKEKRR"
     gene            complement(9494..11818)
                     /locus_tag="BVU_4138"
     CDS             complement(9494..11818)
                     /locus_tag="BVU_4138"
                     /codon_start=1
                     /transl_table=11
                     /product="GH20"
                     /protein_id="ABR41740.1"
                     /translation="MKTLMGLAGLTMAGFMLLSCNTEVKEANYQIIPLPQEISVMDQAA
                     PFILSNGTKIMYPEGNEKMQKNAEFLASYIKDLTGKSLAVQAGTDGKGIILQLGGNAEN
                     PEGYQLKVTSDQVVISGPTEAGVFYGIQTLRKSIPVAQGVDIALPAVEINDYPRFSYRG
                     AMLDVSRHFFPVDSVKRFIDMLALHNINRFHWHLSEDQGWRIEIKSRPELTEIGSKRAE
                     TVIGHNSGKYDGKPYGGFFTQEEAKEIVAYAAERHITVIPEIDMPGHMQAALAAYPNLG
                     CTGGPYEVWKIWGVSEDVLCAGNDETLKFIEDVLGEIIQIFPSEYIHVGGDECPKVRWA
                     KCPKCQARIKALGLKSDKNHTAEERLQSFIINHAEKFLNGHGRQIIGWDEILEGGLAPN
                     ATVMSWRGVAGGIEAAKQKHDVIMTPNTYLYFDYYQTKDIANEPEAIGGYVPVETVYNY
                     EPMPADLTPEEQKYIIGVQANLWTEYIPTYSQVEYMELPRMAALSEIQWTMPEKKNYEG
                     FLKRLPQLVDIYDVYKYNYAKHVFDVNAVFTPNPKDGTLDVTLSTIDNSPIYYTLDGTE
                     PSAASQLYTETLKLKQNCTFKAITVRPAGNSRVVTEEIAFNKASMKPVTMLQPVNKQYE
                     FKGAPTLVDGLKGNGNYKTGRWIAFYKNDMEAVIDMQQPTEISSASISTCVEKGDWVFD
                     ARAFSVAVSEDGKNFKEIASEKYPAMKQDDKNGVFNHTLTFDPVTARYVKVTALAEHSI
                     PAWHGGKGNPAFLFVDEISLN"
     gene            complement(11835..14402)
                     /locus_tag="BVU_4139"
     CDS             complement(11835..14402)
                     /locus_tag="BVU_4139"
                     /note="related to beta-mannosidases"
                     /codon_start=1
                     /transl_table=11
                     /product="GH2"
                     /protein_id="ABR41741.1"
                     /translation="MKKTLKVLMMLGCFPMMLSAKEYKKSESLSLDKGWEFAQVGRNEW
                     LPATVPGTVHQDLISHNKLPNPFYGMNEQKVQWVENEDWVYKTTFNVTDEQLSRDAALL
                     ILEGLDTYADIYLNGSLLERTDNMFVGYTLPVKEVLRKGENHLQILFHSPVKQTLPQWE
                     TNGFDYPADNDHSDKRVSIYSRKAPYSYGWDWGIRLVTSGIWRPVTLTFYDVARIDDYY
                     VRQASVTKDLAKVENRLTVNSVSATPQKAEVTVAYSYKEGEKVTEQKEVTLQPGTNHIL
                     LPIEIRQPHLWMPNGWGEPALYDFEAVIKVDGKVIASQKERIGLRTIKVVKEKDDQGES
                     FYFVVNGEPMFAKGANFIPDDALLPNITEERYRQLFKDVKDANMNMIRVWGGGIYEDDA
                     FYQAADENGILVWQDFIFACTTYPSDPAFMKRVEAEAEYNIKRLRNHASLAMWCGNNEI
                     YEGMRYWGWDKKYTDPGIMEGMKQGYDKLFRELLPRKVAELDPDRFYMHGSPYEANWGR
                     PESWKIADSHNWGIWYGQKPFESLDTEIPRFMSEFGFQAFPEMKTIATFASPEDYALES
                     EVMNAHQKATIGNFLIKKTMGLYYKVPEDFDQLVYMGLVLQGVGVRQGLEAHRRNRPYC
                     MGTLYWQLNDSWPVVSWSSIDYYGNWKALHYQAKRAFAPVLVDAVKEGEDLNIYVMSDK
                     LEADKEVTLLLRVMDFNGKVLTKKSIKGEVPANASTLYYKEPYAGMTTSPQNTFLLMTL
                     KNKKGEVLSEEIYYFNHAKDQELPKTEIRYKVKPMDGKYEVTLSARQLARDVFIEIPVQ
                     GARFTDNFFDLLPGQTKKVIITSDKLKKNEKVDITIKQLSDTN"
     gene            complement(14429..>15265)
                     /locus_tag="BVU_4140"
     CDS             complement(14429..>15265)
                     /locus_tag="BVU_4140"
                     /codon_start=1
                     /transl_table=11
                     /product="sialate O-acetylesterase"
                     /protein_id="ABR41742.1"
                     /translation="MKKTLILILCLFLCTVSFARKRVKVACVGNSITYGIGVSDPDKES
                     YPARLQQMLGEGYTVERFGKPGATLLNKGHRPFMQQKEFKDALAFAGDVVVIHLGVNDT
                     DPRDWPNYRDFFIADYRALIDSFRVANPECRILIARLTPIADRHPRFESGTRDWHDEIQ
                     LAIETIAKYAQVQLIDFHAPLYPYPFMLPDAVHPDKEGAAVLAKTVYEGITGDFGGLQM
                     PEIYTDNMVLQHGRLLTIQGKADAGEKVTVSIDRQKLQAVTGADGKWAVDVRPLKAGGP
                     YTLTVSTEKRKLVYENVLAGEVWLCSGQSNMEFYLNWSATAAQDVPQAANSNIRFYDMK
                     ARWRTDAVEWDASVLDSLNHLQYYKDTRWTVCSPETAGNFSAVAYYFGKKLQDSLQVPV
                     GLICNAIGGSPTEAWIDRSTLEYRFPAILRNWMQNDFIQDWVRGRAALNVKQSSNKLQR
                     HPYEPCYLYESGIRPLEQFPVKGFIWYQGESNAHNREAHEKLFGLLVESWRKNWGDAEL
                     PFYFVQLSSIDRPSWTWFRDSQRRLMAEIPHTGMAVSSDRGDSLDVHPKQKREVGERLA
                     AWALNKTYGYKNVIPSGPLYKSVVFSGGAAYISFDYAEELSTSDGKSLRTFEVAGDDGL
                     FYPAQAVVENGKIKVWSDKVKEPETVRYGWQPFTRANLVNGAGLPASTFRAE"
ORIGIN
        1 ttcttacaaa gtacaagttc cttcgaccag cttgcccatt gcccatacgg cacggatatt
       61 caagtcctgg tcaagaatca agatatcggc atctttgcct ttctgaagtg agcccttgcg
      121 gtcatatact cccataatcc tggacggagt ttccgaagcc atacggacag catcttccaa
      181 tgggatttct gccttttgca ccaaggtacg gatcaaacgg tccatggtag ccacactgcc
      241 tgccaaagca gaacggtcgg ccagtttgca cacaccatcc tcaatgatga cacgagggtc
      301 aaaagctaca ttgctttcac tggcggcaca tgccaaagca tcggtaataa cacaagcacg
      361 ttccacaccc ttaatcttat atatcaggcg caagatagta ggaggaacat gaataccatc
      421 ggctaccact tccactgtca tatcgtctat cagatagata ctttctactg taccttcata
      481 tttatactca cggcgcttat ggaagcccgg catcgcatta tagaaatgtg tagcatgaga
      541 ataaccggac tcccaggctg cacggatatc ttcatattcg gcctgtgtat gtgccacaga
      601 agccaagatg ccttttcctg tgatatactt accaaactgc atggcacccg gcaattcggg
      661 tgcagcatcc caacgcttga tacagcccca cttctctaca ataggaatat attccttcgg
      721 atccgggtct tttatgtttt caggcatctg accgcctgcc atcttcatat taaggtaatg
      781 cccttcaaga tgaagaccaa gtaccggact gtccggttcc gccatcaacc tggtacaagt
      841 ttcggcagct gcctcaatca tcggtacggt agaagaagac aacgttggga aaatactggt
      901 agtaccatgt ttcatgtgag cattaatggc tgtacggaaa gcctcttccg taccttccat
      961 aaaatcaccg ccaccaccac catgacaatg gatttccaca ccaccgggaa caacatacat
     1021 acctttagcg tcaatcagct cggctccgat aacagctaaa tcacaattgg taacttctaa
     1081 aatcttattg tcgcgcataa ggacagatcc gtccttcaac cagccctgtg gggtaagaat
     1141 ctttgcgtta atgatttggg tcaacatgat actatgataa gttagaattt ttaattggca
     1201 tattaaattt gccaacaaaa atagcaactt tttcactttc taaaacagat ttccccaatt
     1261 attttccaac tttttttaat aaataagccc cgcttaataa aatcaagcgg ggcacagata
     1321 gtggaaattg aaacaaatct ttttacttac tcattaaaac tagcctacct gatttaagtc
     1381 ctttacctgt tgcggtcaat atgatttctc ccggtttatc agtactttgc acaacagcag
     1441 tcatcattcc gttaaacact ttcatctgcg gaacatggaa aagttccaat gaagtgggat
     1501 ctccgtttgc accggcacga taggttcccg caccttttac agaatacttg atgagatgct
     1561 gcgcatcggg acaaagatta ccctctttgt ccaccactct tactgtgaca aatgacaaat
     1621 ccttgccatc agcctttatt tcattgcgat ctgtaaccag ttctatatgg tcgggcttgc
     1681 ctgccgtatg gatttccttt tcggccacag cttccccctt atcattatag gcaaccactt
     1741 ttacggttcc cggctcatac tttgtatcca tccacatcaa acggtagcgt ttctggcgtt
     1801 tgaaatctgc tatggaagca gaatccgcac tattttcagc cgttacagtc aaatctttgg
     1861 tacgcttacc ctgactcttg ccattgataa acacttctgc cgacggataa tttgtataaa
     1921 caaagatagg agtcacttct ccttcacgtc ccggccatgt ccaatgagga aggatatgca
     1981 gcgtttcttc atctttgttc caatgactgc ggtacagata gtaacggtct ttgggcaatc
     2041 cggccaggtc gatgataccg aacaaagaag aatggctggg ccaatcagta taataaggag
     2101 tcggttcgcc caaataatcg aagcccgtcc atacaaattc tccgataccc catgcgttat
     2161 cctcatgcca aatccagtca tcctccggca aattggacca accacaatgt tccacatcgt
     2221 aagaagaaga ctgatgatcg tcatatttct tcatagcctg acggacaaca gggaatttat
     2281 agacgccacg cgaacttact gtagaagctg tttcactacc tagaataatc tgctgaggca
     2341 atttcttata gttttctgga tatttatgag ggcggtaatt gaaaccggcc acatccatca
     2401 cagcagccat attattattt actacagcat caggcgcatc cataccttgt gttacaggac
     2461 gggtaggatc ttcacgatga cagatatcct gtaacatacg cgaaagcttt ggtccgttat
     2521 tgccattcca ctggtcgggt acttcgttac cgatgcacca cataacaata ctcggattgt
     2581 tacggtaatg acggatcaga ttagtcagat ccttctccac ccattcatca aatattttat
     2641 gataaccgtt ggccatcttt gccgatttcc actcgtcgaa agactccacc atcagcatca
     2701 tacccatttc atcacaagcc tccaccaatt cgggtgccgg catattatga gaagtacgga
     2761 tggcattaca acccatatct ttcagaatac gaatctgacg acgtatagcg gcatcattta
     2821 cagcaccgcc taacggaccc aagtcatgat ggttacatac ccctttgaat ttggtcagct
     2881 ttccattcag gaaaaagccc ttgccgggaa caatctccaa agtacggata ccaaagcggg
     2941 tggtatattc gtctttcaag gtattccctt catatacttt ggattcagct gtataaagaa
     3001 ccggagtatc aggactccac aactcaggat tagccactgc aaactcctgt tcaaacaaag
     3061 cattatcaaa aacactcaac ttgttttccc cggtagcaac cactttgccg tttttatcct
     3121 tgatctgcgt cacaatacgg taattatcct tattagctcc ttcagggcta accaaagaag
     3181 ttttcaaaga cacttttgca tatttgtctg tcaccacagg agtggtaaca tacgtccccc
     3241 aagcaggaat atgcgtatct tcattgatta ccagatgaac attgcggtac aatccggccc
     3301 ccggatacca acgtgatgat tcaggctcgt tttccaaacg gactgccagt tcgttcctct
     3361 cacccggttt cagataaggg gtcgcatcca cataaaaaga attataaccg tagggccaat
     3421 aaccggcctc ctgcccgttc acataaacac gggcatggct cattgctcca tcaaatatca
     3481 aagtcgcttt cttgcctttc tcaaaaccgg gagcatcaaa gttcaggcga taccatccgg
     3541 ttcctacaaa cggaagacct ccggtacgtc cggcatgttc catcgcctcg gtctgtccat
     3601 cttgagtaat agccatttcc tgcttgtcgt tattgatact gaacggacca taaatcgccc
     3661 aatcatgagg aacggtgacg ttctgccatt tactgtcatt ataaccggga ttggcaaatt
     3721 ccgcattatc ttcacgcgta aatttccatc ctttttcgaa agtctgctct gtacgtacct
     3781 gcgcttgcaa aaaagcaaaa taacaaacag ctcctaacgc agcacacaaa aatcgtttcg
     3841 tattcatagt tatttcttat taggattttc tgttactata aaagtaattt cacctgcctt
     3901 gatcaaatca tcatgcgaaa tcaaatattt attaatcttc ttattgccca gtctgatttc
     3961 ctttatataa tccccttgtc cttctttctt gataaccaat tctttcttgc cccaatattt
     4021 aggatcaagc tgaacggtca ctttatcaaa agtaggagtg gtcaatgtat attcgggcac
     4081 acccggacaa tccggataga atcccatcat actgaatata gcccatgcag acatcgtacc
     4141 cgtatcatca ttgccgggaa ttccatccgg cttagttgtg aaatacttag ccagcaattc
     4201 cttcaccaat ttctgtgtac gccattcttc acctttgaaa cgactgaaca ggtaaggata
     4261 ggctatatcg ggttcattgg ccggatcata attcccttca tcaaacacgc tttgcaattt
     4321 atcaacaaat ttcttgtcgc cccccatcaa ctttaccaag ccattgatat catgaggcac
     4381 aaagaaagtg taattccatg cattaccttc atggaaaccg ggactaggtg caaaattagc
     4441 tccttctttc ggatcaaacg gttcatagaa tttgccttct ttagttatcg gacgcaaggt
     4501 tccgaaatcc ttgctataat aatttttata gcccatagaa cgtttgcgga acaatttcgc
     4561 atcttctttc ttacctaaag cctccgccaa ggtagaaagt gcatagtcgg caacatagta
     4621 ttccaaagca tgagaaaccg aattatcata ctgactttcc atcggcacat accctttgga
     4681 catataatcg tcattatccg gacgcatcag attatccttg cccggagtag tggccgactt
     4741 atacattccc ttataagctt cgtcaatgtc aaagtcttgc aatcccttca tccaactgtc
     4801 taccagaaca ggaatagaag ggtcaccttc catcgtcaat gtttcacgac catacaattc
     4861 ccatttcggg aaccatccgt gttccttgta tatgcccatc atggtgtgaa tcatatccat
     4921 ctgacgctcc ggatatacca aagtcatcaa ctggtgatag ttacgataag tatcccacaa
     4981 tgagaatacc gtgtaacggt tatggttggt ggtcaaaatc ttatctccct ccatttgtgg
     5041 atattgtccg cttacatcct gcaaaatatt cggatgaacc atcgtgtgat acatagcggt
     5101 atagaatact cctttttgct cttccgttcc accttccact ttgatacggg aaagatcatc
     5161 gttccatttc ttacgggctt ccgcacgcag tttgtcgaat gttgtaccga aaggctgttc
     5221 tttttccaga ttcaaacggg cattctctat gctgacaaaa gacacgccca tactgacttc
     5281 aatcacttct tccgctgtgg tatcgtaagt aaaccacact cctatatcat ctccgcttat
     5341 ttcttttgta taagcagtat agagtttgta tttaccggcc gtatcatccc attgcgcctc
     5401 cacacccatc ggacgcatca ttttccaata accgcgtttt gccggtactt tgttgatacg
     5461 cattacaaaa tagataggaa ataccgcctg aggattataa cagaaagttc ccaacaattt
     5521 ggtaccttca atctcacggt cgtttacaaa acgaacggta gcaccactct cattggtcaa
     5581 tccctctccc agattcaaca agatattgct ttgtccggca ggaaaagtaa agcgtgccat
     5641 actggtacgt ggagtggcag tcagttcaca tttcacattg tatttatcca gtatattggt
     5701 ataataaccc ggatttgcag tttcaccttg atagaagctt ccataattat gataatccac
     5761 atccagtttg ccggtggtag gcattaataa caatgatccc aattccggac agcctacccc
     5821 gctaagatta acgtgcgcaa agccggtaag atatttatta ttgaattcgt atggagtgga
     5881 ccaccattgc ttgtctttat ccttatcccc ttcgggaacc cccatcacat tgaaaggagt
     5941 caccgacatc attccatgag gggttaatgc tccggggttt gtcgtaccgt aattagtagt
     6001 acccacaaaa gggtttacat aatctaccgg ctctttctgt gctgccgcag aaaaaactga
     6061 gatacaagcc agaacagccg ataacaaaat ttgtttcttc atgctatttg ttgtttatat
     6121 aagttctatt atttcactac aatttcatct gtaaacaaga aacctccgaa ttcgcccgaa
     6181 gatgcctgat aacgtatgta acgtgctttg gcatttcctt cccaaccaaa gttgatgaaa
     6241 gtcactttgt catccttcac tactttatgc tccatgcgct tcagttccgt aaactcctta
     6301 ccatcattgg aaacggaaat gatcacttct gaaggcataa agacttcagg tccacacacc
     6361 tgcataaagt ctgctccaac agaatgaatt tctgtttctt tttccatatc aatggtcaca
     6421 tccattcttt tcttgtctat aaaaccttgc caacgcctgt caccataagt ccagcctccg
     6481 atcacaccat ctaccaaggc actgtcacca ccggccgaat agccgggata ataagcggca
     6541 tccggtccgt aagccacttt cttacctact gccaaatgct gtacgggctg atccgctccc
     6601 ggacgatttc ctatctcatt tttcaattca aaaggatggt atccttcagc tttcaatgcc
     6661 tctacctctt tcaatgcacg aacatgaaaa tcatcatagt tcttcacaga aggggcactc
     6721 caagcaactt ccgccaaggc aagaatacga ggataaatca tcatttccgc atgttccgga
     6781 gtcggaatat attctgtgaa taaattagct tgtactccat acaccaactg gactttatcc
     6841 gcactcaaag tatcgggtac aggattaaat gaataaactt tggacaaagg cagatagcct
     6901 cctattgctt ccggctggga atcaggagca tcctgataag aatcaaaata gcagaactca
     6961 cccggactca taatagccat gtggccggaa tcaaccgctt tcattccccc ttccgtgcca
     7021 cgccatgaca tgacagtggc attaggtgcc aaaccacctt ccaatatttc atcccaaccc
     7081 aataatttac gtccgtgggc attcaaaaag acctcaatac gatgaatcag ataactctgt
     7141 aactcgttca catctttcaa gccttctttt ttcatacgtg cctggcacag tttgcaagtg
     7201 ggccatgagg ctttacctgc ctcatcccct cctatatgaa tatattcgga cgggaaaagt
     7261 tccattacct ctgtcaacac attttccaga aactcaaaag tcttttcatt accgacacag
     7321 aaatcggctt gtttgtaagg ttcgtgtgta caagacaact caggataagc agtcagtact
     7381 tcttccgaat gcgcaggcat ctctatctca ggaataacag taataaaacg ttcctgagcg
     7441 tatgccacca gttcgcggat atcatcttga gtataataac ctccgtgagc atctttactg
     7501 ccttcttctt cataccgtcg tccgttattc caccattctt tccaggtagg aaactcacgc
     7561 catgccgcaa attctgtcag acggggatat ttttttattt caagacgcca gcccgcagcg
     7621 tcagtaagat gcagatgcag acggttcaat ttataatatg ccaaagcatc catctgcttt
     7681 tttataaatt ccttatcgaa gaaatgacgg gaaacatcca tcataaagcc acgataagca
     7741 aaacggggtt catctgtaat gactcctgcc ggcaatcctt tttcatcaac catttgcagc
     7801 atagtctgaa ctccatagaa caatcctgcc ccggaagttg cacgaataag tacctgatca
     7861 ggagttaccg tcagaacata tccctcggaa gagtttacct ccggcagttc cgccacttgt
     7921 ttcaagacaa cattatgtcc ctcttctgct attaccggtt tcaaattcat ggaagaagcc
     7981 accagataat cttccaaaat cttcttgtcc ccctcagacg catctatata taaccctgtt
     8041 tccgaattca atgaaaacac ttcctgctgt aattccacct ttaatggtgc gggaataaca
     8101 gaaagtgtgc gttgctcttc tttcgtgcaa cttgcaaaca gcaagcccaa tgcaacttcc
     8161 gccaatataa tcaatcttct catcttctct tttctttaat tctattaatt tcattagtac
     8221 gaatgcctgg tttcaattct ccattaataa tgtaatgaaa tccgtcctgc gaaactatta
     8281 cagctccggc acgcgcacct tgttcatatt cgcctaatgt agtccattta tccgtctgcg
     8341 gatgatagag cagcaggttt ctattaaacc gataccactc tacaggatgt gacaaatatt
     8401 cttttcccgc ataaatacct tgcagagctt ttaagaatat atccttatca actcctccgg
     8461 cacacaatat cataccctcg ccaaaagagg ttcccattcc accacctaaa gagatctcat
     8521 taccttccgc atcatacggg gtggcaaccg atgaccattc tttcgtttcc ggagaataca
     8581 tatatccatc tactgacaaa gaagcctgat gcccttcaac agccggggca aatccccccc
     8641 acacataaag ttttccatct tgtgccacgc aaacagattg tactctgggt tcacccggaa
     8701 tatctgtttc tcttttccat cctccagaca aatccgacag atcaagcatg tacatggccg
     8761 aggatggaat gccatttaca tttccaccga caatatatag tgaatgtcct actaatgcac
     8821 ctgccatatt atccatagtt acaggcaaag agggcaaagt atctcttttc aaggtgtctt
     8881 tttgcaaaga taaaagaaaa acatcagaca agctgtgtgt tgccgtagtc cctccaacac
     8941 aaattaaccc tttttcagta gaaatagtga ctccataagc tgctgcctga ggcagttggc
     9001 ctattttctt ccactcaaaa gccgtatcat ttgacaaagg ggcgatatat atatcccgat
     9061 aataagcttt ttttcctcca tcggctaccg gtatatcagg gaaattacaa cctccggcta
     9121 tcagcaaatt tccttcaatc actcccgcat ataatgcaga aactccctta agaaaaccgg
     9181 tattctctgt agggaaccca tgcattttct caagagatat ttcagaagca tccgattgac
     9241 cgctacaagc agccattgtc atcatgccca gtatcgcata aacgccatat attatttttc
     9301 tgatcatgtt ttcatggtga agcaaataat aaaaagtgtg ccaaaagcaa atcagccatc
     9361 ccgcttgccc cagaaacgga ttgcaccaac gcaaacacag cattccttac gcatatggac
     9421 ggaggcattc cacctcacgc ccaacggtac tctatcacac ttttggcaca cagtcattat
     9481 ttgaatataa ctatcaattt aatgaaattt catcaacaaa caagaaagcc ggatttcctt
     9541 tgccaccgtg ccaagcagga atgctatgtt ccgctaaagc ggtcactttc acataacggg
     9601 cagtcaccgg atcgaaagtc aacgtatggt tgaacactcc attcttgtca tcctgcttca
     9661 ttgccggata tttttctgaa gcaatttcct taaagttctt tccgtcttcg gatacagcta
     9721 cagaaaaagc acgggcatca aacacccagt cacctttttc cacacaagta gaaatagaag
     9781 cgctgctgat ttctgtcggt tgctgcatat caataactgc ttccatatca tttttataga
     9841 aagcaatcca acggcccgtc ttatagttac cgttaccttt caatccgtcc accaaagtgg
     9901 gagcgccttt gaattcatat tgcttgttta ccggttgcaa catagtgaca ggtttcatac
     9961 tagccttgtt aaaagcaatt tcctctgtaa ccacacggct atttcctgca ggacgtacag
    10021 taatcgcttt aaaagtacaa ttctgtttca atttcaatgt ttccgtatac aactgggaag
    10081 cagcggaagg ttccgttcca tccaaagtgt aatagatagg actattatca atagtagaca
    10141 aagtaacatc cagcgtacca tctttcggat taggagtaaa tacagcattt acatcaaaga
    10201 catgcttggc ataattatat ttataaacat cataaatatc taccaactga ggcaaacgct
    10261 tcaagaaacc ttcatagttt ttcttttccg gcatggtcca ctgaatttca gacaaagcag
    10321 ccatacgggg taattccata tattctacct gactgtaggt aggaatgtat tcagtccata
    10381 agttggcctg tacgccaatg atgtatttct gctcttccgg agtcagatca gccggcatcg
    10441 gctcatagtt atatactgtt tcaacgggta catatccacc aatagcctca ggttcattag
    10501 caatatcctt ggtttggtaa tagtcgaaat acaaataagt attaggagtc ataattacat
    10561 catgtttctg ttttgcggct tcaatacctc cggcaacacc acgccatgac attacagtgg
    10621 cattgggagc caatccgcct tccagaattt catcccaacc gataatctga cgtccgtgtc
    10681 cgttcaggaa cttctctgca tgattgataa tgaaactctg caatctttcc tcggcagtat
    10741 gattcttgtc agacttaaga cctaaagcct tgatacgagc ctggcacttt ggacattttg
    10801 cccaacgtac cttaggacat tcgtcaccac ctacatgaat atattctgat gggaaaatct
    10861 gaataatttc ccctaataca tcttcaatga atttcaaggt ttcatcattt cctgcgcaaa
    10921 gcacatcttc tgataccccc cagattttcc atacttcgta cggaccacca gtacagccca
    10981 agttaggata tgcagccaaa gcagcctgca tgtgtcccgg catatcaatt tccggtataa
    11041 ccgtaatatg acgttcggca gcataagcta caatttcttt tgcttcttcc tgtgtgaaga
    11101 atccaccata aggcttgcca tcatattttc ccgagttatg tccgataacc gtttccgctc
    11161 ttttagaacc tatttcagtc agttcaggac gactcttgat ttcgattctc catccctggt
    11221 cttcagacaa atgccagtgg aaacggttga tgttgtgcaa agccagcata tcaataaaac
    11281 gctttacaga atctaccggg aaaaaatgac gtgacacatc caacattgca ccacgataag
    11341 agaaacgagg atagtcattg atttcaaccg ccggtaaagc gatatccact ccttgtgcta
    11401 ccggaataga tttacgcaac gtctggatgc cataaaatac tccggcttcc gtaggtcctg
    11461 aaataaccac ttggtcgctg gttaccttta actggtatcc ttcaggattt tcagcatttc
    11521 cacctaattg caggattatt cctttgccgt ctgtaccggc ttgtacagcc aatgactttc
    11581 cggtaagatc tttgatataa cttgccaaaa attcagcgtt cttttgcatt ttttcattgc
    11641 cttccggata cattatctta gttccatttg acaaaataaa cggagcagcc tgatccatta
    11701 ccgaaatttc ctgcggtaac ggaattatct gataatttgc ttctttcact tctgtgttac
    11761 aggataaaag cataaaacct gccattgtca gccctgcaag gcccattaaa gttttcataa
    11821 tagatattaa ttgattagtt agtatcactt aattgcttaa tagttatatc aaccttttca
    11881 ttcttcttca gtttatctga agtaataatc actttctttg tctgtcccgg caacaagtca
    11941 aagaagttgt cagtaaatct cgcaccctga acaggaatct ctatgaacac atccctggcc
    12001 agctgtctgg cagacagagt cacttcatat tttccatcca tcggcttcac tttatagcgg
    12061 atctcggtct tcggaagctc ctgatctttt gcgtggttaa agtaataaat ttcttcggat
    12121 aaaacctcac ctttcttatt ttttaatgtc attagaagaa aagtattttg aggacttgtt
    12181 gtcatacctg cataaggttc cttataatat aaggtggaag cattggccgg aacctcgccc
    12241 ttgatactct ttttagtcag aacctttcca ttaaaatcca tcacacgcaa caataaagtc
    12301 acctctttat ccgcttccag tttgtccgac ataacataaa tattcaaatc ctccccttcc
    12361 ttgacagcat ctaccaatac cggagcaaaa gctctttttg cctgataatg caacgctttc
    12421 caattgccat aataatcaat gctcgaccag gaaacgaccg gccagctgtc attcagctgc
    12481 caatataaag ttcccataca atagggacgg ttacgacgat gggcttccaa accctggcgc
    12541 actcctaccc cctgcaaaac caaacccata taaaccaact gatcgaaatc ttcaggcact
    12601 ttataataca gtcccatagt cttcttgatg aggaaattac cgatagtggc tttttgatga
    12661 gcattcatca cctccgattc caatgcataa tcttccggtg aggcaaaagt agcaatcgtc
    12721 ttcatttcag gaaatgcctg aaaaccaaac tcactcataa aacgcggaat ttccgtatcc
    12781 agactttcaa acggtttctg accataccag ataccccaat tatggctgtc ggcaatcttc
    12841 caactttcgg gacgtcccca attggcctcg tacggagaac catgcatata gaaacggtcc
    12901 ggatcaagtt cagctacttt acgaggcaac aactcacgga aaagtttgtc atagccctgc
    12961 ttcattcctt ccataatacc gggatcagtg tatttcttat cccatcccca gtagcgcata
    13021 ccttcataaa tttcattgtt tccacaccac atagccagac tggcatggtt ccgtaaacgc
    13081 ttgatattat attccgcctc ggcctctacc cgtttcataa aagcaggatc ggacggataa
    13141 gtagtgcagg caaaaataaa atcctgccaa actaaaattc cattctcgtc cgccgcctgg
    13201 taaaaagcat catcctcata aattcctcca ccccatacac gaatcatatt catattggca
    13261 tctttcacat ccttgaacaa ctggcggtaa cgttcttcag taatgttagg cagcaaagca
    13321 tcatccggga taaaattcgc gcctttggca aacataggtt caccattgac tacaaaatag
    13381 aaggattctc cctgatcgtc tttttctttc accaccttta ttgtacggag tccgatacgc
    13441 tctttttgag aagctatcac tttaccatcc acctttatta cggcttcaaa gtcatacaat
    13501 gcaggttccc cccaaccatt aggcatccat aaatgaggct gccgtatctc tatgggaaga
    13561 agaatatggt ttgttcccgg ctgcaatgtc acctctttct gttcggttac cttttcaccc
    13621 tccttataag aataagcaac ggttacttcc gctttctgag gagttgcaga aacactgttt
    13681 acagtcaggc ggttttcaac tttcgccaga tcttttgtta ccgaagcctg acgtacatag
    13741 taatcatcaa tgcgtgccac atcatagaaa gtcagtgtca caggccgcca gataccactg
    13801 gttaccaagc ggattcccca atcccagcca taactgtaag gcgctttacg gctatagata
    13861 ctaacccgct tatcactatg atcattatca gcaggataat caaaaccatt ggtttcccat
    13921 tggggtaaag tttgcttgac aggtgaatga aacagaatct gcaaatggtt ttctcccttc
    13981 cgcaacacct cttttaccgg aagagtatag ccgacaaaca tattgtccgt acgttccaac
    14041 aaagagccgt tcaggtaaat atccgcatac gtatccaacc cttccaaaat caacaaggca
    14101 gcatcccgcg agagttgctc atccgtcaca ttaaaagtag ttttatagac ccagtcctca
    14161 ttctccaccc actgcacttt ttgctcattc atcccataaa atggattggg cagcttatta
    14221 tgagaaatca aatcctgatg taccgttccg ggcaccgtag ccggcaacca ttcattccgg
    14281 ccgacctggg cgaactccca tcccttatca agactcagac tctctgactt cttatactcc
    14341 tttgcactga gcatcatcgg aaagcatcct aacatcatca aaacttttaa tgttttcttc
    14401 atcttaccta tctttattaa tttatatact attcagcccg gaatgtggat gcaggcaaac
    14461 cggcgccatt taccagattg gcacgggtaa atggctgcca tccgtaacga accgtttccg
    14521 gctctttcac cttgtcactc catactttta ttttaccgtt ttcaacaaca gcctgtgccg
    14581 gataaaataa tccatcatca cctgccactt cgaatgtacg aagcgatttc ccatccgaag
    14641 tcgacaactc ctccgcataa tcaaaagaaa tataagccgc acctccacta aatacgaccg
    14701 atttataaag cggtcccgaa ggaatgacat ttttatatcc gtatgtttta ttcaaagccc
    14761 atgcagccaa ccgttcaccg acttctcttt tctgtttggg gtgtacgtcc aatgagtctc
    14821 ccctatctga actgacagcc ataccggtat gaggaatctc cgccatcaaa cgacgctggc
    14881 tatcacggaa ccaagtccat gacggacggt ctatactgga caattggaca aaatagaatg
    14941 gaagttccgc atccccccaa ttcttgcgcc aactttccac caacaatccg aacaactttt
    15001 catgagcctc ccgattatgg gcattggact caccctgata ccaaataaag cctttgaccg
    15061 gaaactgttc caaaggacgg atacccgatt catacaaata acaaggctca taaggatggc
    15121 gttgcaattt attggaagac tgctttacat tcaaggcagc acgcccacgc acccagtctt
    15181 gaataaaatc attctgcatc caattacgta agatagccgg aaaacgatat tccaatgtac
    15241 tacggtctat ccatgcttca gtagg
//
