LOCUS       NC_004350               4509 bp    DNA     linear   CON 10-MAR-2020
DEFINITION  Streptococcus mutans UA159, complete sequence.
ACCESSION   NC_004350
VERSION     NC_004350.2
DBLINK      BioProject: PRJNA224116
            BioSample: SAMN02604090
            Assembly: GCF_000007465.2
KEYWORDS    RefSeq.
SOURCE      Streptococcus mutans UA159
  ORGANISM  Streptococcus mutans UA159
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4509)
  AUTHORS   Ajdic,D., McShan,W.M., McLaughlin,R.E., Savic,G., Chang,J.,
            Carson,M.B., Primeaux,C., Tian,R., Kenton,S., Jia,H., Lin,S.,
            Qian,Y., Li,S., Zhu,H., Najar,F., Lai,H., White,J., Roe,B.A. and
            Ferretti,J.J.
  TITLE     Genome sequence of Streptococcus mutans UA159, a cariogenic dental
            pathogen
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 99 (22), 14434-14439 (2002)
   PUBMED   12397186
REFERENCE   2  (bases 1 to 4509)
  AUTHORS   Ajdic,D., McShan,W.M., McLaughlin,R.E., Savic,G., Chang,J.,
            Carson,M.B., Primeaux,C., Tian,R., Kenton,S., Jia,H., Lin,S.,
            Qian,Y., Li,S., Zhu,H., Najar,F., Lai,H., White,J., Roe,B.A. and
            Ferretti,J.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-SEP-2011) Department of Microbiology and Immunology,
            University of Oklahoma Health Sciences Center, 940 SL Young Blvd.,
            Oklahoma City, OK 73104, USA
  REMARK    Sequence update by submitter
REFERENCE   3  (bases 1 to 4509)
  AUTHORS   Ajdic,D., McShan,W.M., McLaughlin,R.E., Savic,G., Chang,J.,
            Carson,M.B., Primeaux,C., Tian,R., Kenton,S., Jia,H., Lin,S.,
            Qian,Y., Li,S., Zhu,H., Najar,F., Lai,H., White,J., Roe,B.A. and
            Ferretti,J.J.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-JUL-2002) Department of Microbiology and Immunology,
            University of Oklahoma Health Sciences Center, 940 SL Young Blvd.,
            Oklahoma City, OK 73104, USA
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/10/2020 06:12:25
            Annotation Pipeline               :: NCBI Prokaryotic Genome
            Annotation Method                 :: Best-placed reference protein
            Annotation Software revision      :: 4.11
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
            Genes (total)                     :: 1,994
            CDSs (total)                      :: 1,910
            Genes (coding)                    :: 1,858
            CDSs (with protein)               :: 1,858
            Genes (RNA)                       :: 84
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 52
            CDSs (without protein)            :: 52
            Pseudo Genes (ambiguous residues) :: 0 of 52
            Pseudo Genes (frameshifted)       :: 33 of 52
            Pseudo Genes (incomplete)         :: 15 of 52
            Pseudo Genes (internal stop)      :: 19 of 52
            Pseudo Genes (multiple problems)  :: 14 of 52
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence was derived from
            AE014133.
            On Sep 26, 2011 this sequence version replaced NC_004350.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotation Pipeline (PGAP)
            set; GeneMarkS-2+
            repeat_region
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..4509
                     /organism="Streptococcus mutans UA159"
                     /mol_type="genomic DNA"
                     /strain="UA159"
                     /db_xref="taxon:210007"
     gene            complement(1..1629)
                     /gene="treC"
                     /locus_tag="SMU_RS09320"
                     /old_locus_tag="SMU.2037"
                     /old_locus_tag="SMU_2037"
                     /db_xref="GeneID:1029221"
     CDS             complement(1..1629)
                     /gene="treC"
                     /locus_tag="SMU_RS09320"
                     /old_locus_tag="SMU.2037"
                     /old_locus_tag="SMU_2037"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002284913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH13_29|GH13"
                     /protein_id="WP_002262351.1"
                     /db_xref="GeneID:1029221"
                     /translation="MTLDKRKVVYQIYPKSYKDTSGNGVGDLQGIIEKLPYLEELGIDV
                     IWLNPFYPSPQRDNGYDVSDYTAVNPLFGSMADFEELVRKGKEHGIEIMLDMVLNHCSI
                     EHEWFQKALAGDKYYQDFFILRDRPTDWVSKFGGNAWAPFGETGKYYLHLYDVTQADLN
                     WRNPHVREELFKVVNFWRNRGVKGFRFDVINVIGKDEVLKDNPHFDGKPEYTDRPINHD
                     YLKMLNKASFGQDENGMTVGEMSFTDIPNCIQYSNPDNHELDMVFNFHHLKVDYENGQK
                     WTRKTFDFEELKHLFHTWGEGMSQGNGWSALFWNNHDQPRALNRFVDIKQFRNEGATML
                     AASIHLSRGTPYIYMGEEIGMIDPDYGSMADYVDVESLNAYQELIDKGKSSEEAFHIIR
                     AKSRDNARTPMQWDTSENAGFSTGRPWLKVGKSYPQINVANEKQGKIFPFYQKLIRLRK
                     EMPLIAQGSYQAALTDSDKIYAFEREYEGQKLLVLNNFFAETVELDLPSLYQAGTVLIS
                     NYDDVILDKRISLKPYQTVAILAEV"
     gene            complement(1655..3622)
                     /gene="treP"
                     /locus_tag="SMU_RS09325"
                     /old_locus_tag="SMU.2038"
                     /old_locus_tag="SMU_2038"
                     /db_xref="GeneID:1029225"
     CDS             complement(1655..3622)
                     /gene="treP"
                     /locus_tag="SMU_RS09325"
                     /old_locus_tag="SMU.2038"
                     /old_locus_tag="SMU_2038"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q720G7|4.A.1.2.13"
                     /protein_id="WP_002262352.1"
                     /db_xref="GeneID:1029225"
                     /translation="MGKFEKDAKVLLDAIGGKENVSAVTHCATRMRFVLNDESKADVKT
                     IEAIPAVKGTFTNAGQFQIIIGNDVPLFYNDFTAVSGIEGVSKETAKSAAKSHQNPIQR
                     VMTLLAEIFTPIIPAIIVGGLILGFRNVIDQVQWGFLDGQTIAQHSQFWSGISSFLWLP
                     GEAIFQFLPVGIVWSVSRKMGTSQILGIVLGICLVSPQLLNAYNVASTPAAEIAKKWVW
                     DFGFFTVRRIGYQGQVIPALLAGLSLSYLEIFWRKKIPEVVSMIFVPFLSLIPALILAH
                     TVLGPIGWTIGQWISTIVYAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAIDTQLVA
                     DTGGTGLWPMIALSNIAQGSAVFAYYLMNRHEEREAQVSLPATISAYLGVTEPALFGVN
                     IKYVYPLVAGMIGSSIAGFLSVTFNVTANAIGIGGLPGILSIKVKYMLPFFIIMLVAIA
                     VPMVLTVFFRRINFLTKSEDEAHQEKTETAEISASEKTNEPAVGTTFEIKSPLKGQVKP
                     LSEAVDPVFAQGVMGQGVLIDPSEGLLTSPVNGVVSVLFPTKHALGLVTDQGLELLIHI
                     GMDTVNLEGKGFETYVKQGDTIKVGDKLIRFDIDAIHQAGYTTETPVIVTNQNDYQPDV
                     VGSLPREIERGEVLLTASKI"
     gene            3796..4509
                     /gene="treR"
                     /locus_tag="SMU_RS09330"
                     /old_locus_tag="SMU.2040"
                     /old_locus_tag="SMU_2040"
                     /db_xref="GeneID:1029228"
     CDS             3796..4509
                     /gene="treR"
                     /locus_tag="SMU_RS09330"
                     /old_locus_tag="SMU.2040"
                     /old_locus_tag="SMU_2040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019805181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STP|GntR"
                     /protein_id="WP_002273717.1"
                     /db_xref="GeneID:1029228"
                     /translation="MKKYEIIFKKLEEDILKGHYQMGDYLPPEMELSQTYASSRDTVRK
                     ALQLLTKAGFIKTVQGRGSQIIKRERINFPVSQLTSYQELVKQLQMNVKTNVIAIDKLI
                     VDEKLTKLTGFENKGLVWRITRQRVIDGVASILDTDYLDKALIPHMTREIAEHSIYDYL
                     ENQLKLDIAYAQKIITIDQVSQKDKILLDLDSENHVVSVKSKVYLSNQQQFQFTESRHK
                     LEKFRFVDFARRHRD"
ORIGIN
        1 tcagacttct gctaaaatcg ctactgtctg ataaggtttt aaggaaatcc gtttatctaa
       61 gataacatca tcgtaattac taatgagaac ggtccctgct tgataaaggg aaggcaagtc
      121 tagctcaact gtttcagcaa agaaattatt gagaaccagc agcttttggc cttcgtactc
      181 tcgttcaaag gcatagattt tatcactgtc tgtcaaagct gcttgataac tgccttgagc
      241 aattagcggc atttcttttc gcaaacgaat caatttttga taaaaaggaa agatcttacc
      301 ttgtttttca ttagccacat tgatttgtgg gtagctcttt ccaaccttca gccacggcct
      361 gccagttgaa aaacctgcat tctcgctagt atcccattgc ataggggtac gtgcattatc
      421 acgcgatttg gctcgaataa tgtgaaaggc ttcctcagaa gatttgcctt tatctattaa
      481 ttcttgatag gcattcaggc tttccacatc aacataatca gccatagaac catagtctgg
      541 atcaatcatg ccaatttctt cccccatata aatatagggc gtaccacgag ataaatgaat
      601 cgaggctgca agcatggtcg ctccttcatt gcgaaactgc ttaatatcaa caaagcgatt
      661 aagcgctcgt ggctgatcgt gattattcca aaagagagca gaccagccgt taccttgact
      721 catcccttca ccccaagtat gaaagagatg tttcagttct tcaaaatcaa acgttttgcg
      781 tgtccatttt tgaccatttt cataatccac tttaagatga tgaaaattaa agaccatatc
      841 caattcatgg ttgtcgggat tgctgtattg tatgcagtta ggaatgtctg taaaactcat
      901 ctcgccaaca gtcataccat tttcatcctg accaaagctg gctttattga gcatttttaa
      961 ataatcatga ttaatgggac ggtctgtata ttcaggtttc ccatcaaaat gaggattatc
     1021 ctttaggacc tcgtctttcc caatcacatt gataacatca aagcgaaagc ccttgactcc
     1081 cctgttgcgc cagaaattga ccaccttaaa cagttcctca cgaacgtgag gattgcgcca
     1141 atttaaatca gcctgcgtga catcatacag atgcaggtaa tacttccctg tctctccaaa
     1201 aggtgcccaa gcattgcccc cgaatttaga aacccagtca gtaggcctat ctcttaaaat
     1261 aaagaaatcc tgataatact tatctccagc caaggccttt tggaaccatt cgtgttctat
     1321 cgaacagtga ttgagtacca tgtccagcat gatctcaatg ccatgctctt ttcctttgcg
     1381 tactaattct tcaaaatcgg ccatgctccc aaataaagga ttcacagcag tatagtcaga
     1441 cacatcatag ccgttatcgc gctgtggact aggataaaat gggttgagcc agataacatc
     1501 aattcccaat tcttctaaat aaggtaattt ttcaataatt ccctgaagat ccccgacccc
     1561 atttccactt gtgtctttat acgatttggg ataaatttga tagacaactt tccttttgtc
     1621 taatgtcatt ttattctcct tacaataatt gatcctatat tttgcttgct gttaagagga
     1681 cctcaccgcg ttcaatttca cgaggaaggc ttccaacgac atcaggctgg tagtcatttt
     1741 gattggtgac aataacaggt gtctctgtag tataacctgc ctgatggata gcatcaatat
     1801 caaaacgaat caatttgtct ccgaccttga tcgtatctcc ttgtttgaca tatgtttcaa
     1861 aaccttttcc ttccagattg accgtgtcca taccaatatg gatcaataat tcaagtcctt
     1921 gatctgttac aagaccaaga gcatgttttg ttggaaagag gacagaaacc acaccattaa
     1981 caggagacgt taagagacct tcacttggat caatcaaaac accttgtccc atgacacctt
     2041 gggcaaaaac aggatcaacc gcttcagaca aaggtttgac ttgacccttt aaaggacttt
     2101 taatctcaaa cgttgttcct acagcaggtt cattagtctt ttctgatgct gatatttcag
     2161 cagtttctgt tttttcttga tgagcttcat cttcagattt agtgagaaag ttaatcctac
     2221 ggaagaaaac tgttaaaacc ataggaactg cgatagcaac taacataatg atgaaaaatg
     2281 gaagcatgta tttaactttg atagacaaaa ttcctggaag accaccaata ccaatagcat
     2341 tagctgttac gttaaatgtg actgaaagga agcctgcaat ggaagagcca atcattccag
     2401 ctacaagagg ataaacatat ttgatattca ccccaaaaag tgctggttct gtcacaccaa
     2461 gataagctga gatagtggct ggaagtgaaa cttgtgcttc acgttcttca tgacggttca
     2521 taagataata agcaaatact gctgatcctt gagcaatatt agaaagagca atcattggcc
     2581 atagtcctgt acctcctgta tctgctacta attgcgtatc aatagcatta gtcatatgat
     2641 gtagaccagt gataacaaat ggcgcataaa gagctccaaa gatagctcca aaaagccact
     2701 taacaggacc ggttagacct gcatatacaa ttgttgaaat ccattgtcca atagtccagc
     2761 caattggccc cagaacagta tgggctaaaa tcaatgctgg gataagagat aaaaagggaa
     2821 caaaaatcat ggaaaccact tctggaattt tcttgcgcca aaagatctca agatacgaaa
     2881 gagaaagtcc agctagtaaa gctgggataa cttgcccttg ataaccaata cgtctcaccg
     2941 taaagaaacc aaaatcccaa acccattttt tagcgatttc agctgcgggt gtactagcta
     3001 cattataggc attcagcagc tgcggtgaaa ccaaacaaat tccaagtaca atacctaaaa
     3061 tttgactcgt tcccatctta cggctgacag accaaacaat acctacaggt aaaaattgga
     3121 agatggcttc gcccggcagc catagaaatg aactgatacc actccaaaat tgtgaatgct
     3181 gtgcgattgt ttgtccatct agaaatcccc attgaacctg atcaatgaca ttacgaaatc
     3241 caagaatcag ccccccaaca atgatagctg ggataatagg ggtgaaaatt tctgctaaca
     3301 gagtcatcac acgctgaata ggattctgat ggcttttagc agccgactta gcggtttcct
     3361 tagagacccc ttcaatacct gaaacagctg taaaatcatt ataaaacaaa ggaacatcat
     3421 tcccaataat aatttggaat tgccccgcat tggtaaaagt tccctttaca gccggaatag
     3481 cttcaattgt cttaacatcg gctttacttt catcatttaa aacaaagcgc atacgtgttg
     3541 cacaatgtgt aacagcagaa acattttctt tgccgccaat agcatctagt aataccttgg
     3601 catctttttc aaattttccc ataaattttt cctaggttaa cctagtcctc ctttaatatg
     3661 ataacagtac gtttactttt tcattgtaaa cgattacaaa tttgttggca agttgtccat
     3721 aggaaaaaag cgcaattttt gttaaaataa agtcagttgt atgcattttt ttagacaaat
     3781 tagattgaat tgcttatgaa aaaatatgaa attattttta aaaaactaga agaagatatt
     3841 ctcaaaggac actatcaaat gggtgactat cttccccctg aaatggaact tagccagacc
     3901 tatgccagca gccgagatac tgttagaaag gctttacagc tcttgactaa ggcaggtttt
     3961 attaaaacag tacagggaag gggatcccaa attatcaagc gtgagcgcat taactttcct
     4021 gtttctcaac taaccagcta tcaagaattg gttaaacaat tgcagatgaa tgtcaagaca
     4081 aatgttattg ctattgataa actgattgtt gatgagaaac tcaccaaact aaccggtttt
     4141 gaaaataaag gtcttgtctg gcgcatcaca agacagcgcg tcatagacgg cgttgcttcc
     4201 attttagata cggattattt ggataaagca ttgattcctc atatgaccag agaaatcgct
     4261 gaacattcta tctatgatta tcttgaaaat caacttaagc tggacattgc ctatgctcaa
     4321 aagattatta ccatagatca agtatcgcaa aaagataaaa ttttgcttga tttggattct
     4381 gaaaatcatg tcgtttcggt taaatctaaa gtttatctca gtaatcagca gcaatttcaa
     4441 ttcactgaaa gccggcacaa actggaaaag ttccgttttg ttgactttgc cagacggcat
     4501 cgtgattaa
//
