LOCUS       HE717008               14714 bp    DNA     linear   ENV 16-AUG-2013
DEFINITION  Uncultured bacterium fructooligosaccharides degrading DNA fragment,
            clone MetaPbio 9a.
ACCESSION   HE717008
VERSION     HE717008.1
KEYWORDS    ENV.
SOURCE      uncultured bacterium
  ORGANISM  uncultured bacterium
            Bacteria; environmental samples.
REFERENCE   1
  AUTHORS   Cecchini,D., Laville,E., Laguerre,S., Robe,P., Leclerc,M., Dore,J.,
            Henrissat,B., Remaud-Simeon,M., Monsan,P. and Potocki-Veronese,G.
  TITLE     Functional metagenomics reveals novel pathways of prebiotic
            breakdown by human gut bacteria
  JOURNAL   PLoS One (2013) In press
REFERENCE   2  (bases 1 to 14714)
  AUTHORS   Sandrine,L.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-FEB-2012) LISBP, INRA, 135 avenue de Rangueil, 31077
            Toulouse, FRANCE
FEATURES             Location/Qualifiers
     source          1..14714
                     /organism="uncultured bacterium"
                     /mol_type="genomic DNA"
                     /isolation_source="host distal ileum mucosa sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:77133"
                     /clone="MetaPbio 9a"
                     /environmental_sample=""
                     /note="fructooligosaccharides degrading clone"
     CDS             <1..107
                     /note="MetaPbio_contig9a_10--FOS"
                     /codon_start=3
                     /transl_table=11
                     /product="putative partial protein"
                     /protein_id="CCG34773.1"
                     /translation="DQFETLAQAGVRSALEGKTTLQEVMNDPSFHKLF"
     CDS             569..1423
                     /note="MetaPbio_contig9a_20--FOS"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine kinase"
                     /protein_id="CCG34774.1"
                     /translation="MTKKVAVINDLSGLGRCSLTAAISVLSAMGIQACPLPTAILSSQT
                     EYPSYYCYDFTDKMDYFRQEWKKLGTSFSGIYTGYVASVCQIEQIMHFLDTFQTADTFL
                     LVDPVMGDDGVTYDMYTSGLLTAMKELAARADVITPNLTEFCLLTDIDYNSLQDPSLSI
                     QQLISRLKDAGQTLTKDHEKKVLITGIHFTADDGVHKIGNLLLDGSSHFLSAYPCCNGS
                     YSGTGDLFASCITGGLARDISLTEMMQTAGSFLEKSLIDSVEEHVPVNEGVNFEKYLYL
                     LHT"
     CDS             complement(1566..2996)
                     /note="MetaPbio_contig9a_30c--FOS"
                     /codon_start=1
                     /transl_table=11
                     /product="GH32"
                     /protein_id="CCG34775.1"
                     /translation="MNALTRDLVKLVETAEQSQKTREELSVSDRKFREKLHLMPPVGWL
                     NDPNGLCQFQGIYHAFFQYSPFNAEGGVKMWGHYTSKDMIKWEYQGTALYPDQPFDCHG
                     VYSGSAFIEDGKMYLYYTGNVKLEDGEYDYIRTGREGNTVLVITEDGKTFGKKKELMRN
                     SDYPDDLTCHVRDPKVWKENGTYYMVQGARTNKDVGQVLVFESEDKVNWKFRNRVESEK
                     PFGYMWECPDYFKIGDKKLLSTSVQGLEGGIWEDRNVYQSGYFEIEGDILGEYKLSEYH
                     LWDYGFDYYAPQSFETEDGRRIHISWMGMPDCEEYSNPTIQTGWQHCFTFPREIFEKDG
                     KICQRPIRELEEKKHLVSDVKGMLAGEGYPVYEMTISDITKNRFKVILSEKLILDYADG
                     KFRMHFTDQDKTSVSSGRSMRYVEVEEVENLKILADTSSVEVFVNDGEYVFSTRYYPEV
                     YKLQAEAVGAQITLSEIM"
     CDS             complement(3042..4973)
                     /note="MetaPbio_contig9a_40c--FOS"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q8NMD6|4.A.1.2.12"
                     /protein_id="CCG34776.1"
                     /translation="MDYRKTAQDILDHVGGSKNIASAAHCATRLRLVIADNKKVSKEAL
                     ENIDGVKGVFEASGQLQIILGTGTVNKVFAEFIDIAGITASSKAEAKEAAAEKQNWFMR
                     AIKLLGDIFVPIIPAIVASGFLMGIMNSLDFMNSNGFLHINTHSSIYVFANLFSNIAYT
                     FLQILIAFSAAKAFGANQYLGAVIGMIMIHPSLQNAYTVATEGVQQTQSVFFGLFKIDM
                     VGYQGHVIPVIIAVWILAVIEKKLHKIVPEVLDLFVTPLVSVFVTGYLTLSIVGPIFVW
                     AENAILGAIQWMLTLPLGIGSLIMGGLYAPTVVTGIHQMYTAIDIGQLAKYGVTYWLPL
                     ASAANVAQGAAALAVGIKSKDKKIKSLALPSSLSAFMGITEPAIFGVNLRFFKPFIAGC
                     IGGGCGALYASLVHLGAKGTGVTGIFGILLCLNQPLQYLIEMVIAVGVAFVISFLIYKD
                     AEPKAATADAAETAAVENMETTDAVATADTTAETAEETLTSPVNGTQIPLAEVADETFA
                     SEMLGATVAVEPADGKIVAPCDGEVSNIFETGHAVCITTESGGELLIHIGIDTVKMDGK
                     GFTKKVSDGDKVHAGDILVEADLEEIKNAGYQTTTMMILTNTDEFGNVTKAEPAEVKTT
                     SKVMTLTK"
     CDS             complement(5176..6225)
                     /note="MetaPbio_contig9a_50c--FOS"
                     /codon_start=1
                     /transl_table=11
                     /product="DBD-Pfam|LacI,DBD-SUPERFAMILY|0036955"
                     /protein_id="CCG34777.1"
                     /translation="MTIKEIAKLAGVSSAAVSRYLNGGYVSDEKKEQIKKVIDETGYQP
                     SAQARMLRTKKACLIGVVVPKINSESISRITAGIEKVLSERNYQMLLAGTDNTPAKEIE
                     YMRLFENYPVDGIILVGTMITAEHRRFLKESKVPVVVIGQHTKYANCIYHDDYGAGEAM
                     GCAVAAKSRKEIAYIGVSREDKAAGAAREDGFREGLKRSGKELKDGYYKVAEFTTESGY
                     EKVLELLNEKHDIDIISCATDTIAAGAIEAIHTYAGSQIPKNVEDTGSRFRYILENTSI
                     QVTGFGDNQLLKAVTGGIPTVHFGYKTSGIRGAELLLDVIERDESIPVEIKLGFRLANI
                     DDPEENIED"
     CDS             complement(6370..8076)
                     /note="MetaPbio_contig9a_60c--FOS"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q9WYC4|3.A.1.135.5"
                     /protein_id="CCG34778.1"
                     /translation="MKKLLKLIGKYKIFLAFSVIFAAISVVLQLYVPVLFGDAIDEVVS
                     AHQVNFDMMWYYLKQILIFIVISAFATWFMNLLNNRMTYRIVQDIRSQAIRHIQVLPLS
                     YLDQHSTGDIVSRVIADTDILSDGLLLGFTQLFSGIVTIVVTLIFMFSKNVWVTLLVIV
                     LTPFSFVVAKFISSRSYTMFRKQSETRGRQTALIEEMIGGQKVVKAFGYEKESSRRFDE
                     INKELQNYSQKAVFYSSLTNPSTRFVNNIIYAGVALLGAFLIPGGTLTVGGLSVLLAYA
                     NQYMKPFNDISSVVTEMQNALACADRIFDLLEQKEETLDAEGAFATVDGNVTIDDVAFS
                     YDKEKELIENFNLDVKPGMRIAIVGPTGCGKTTFINLLMRFYDVDEGKILVDGKDIREV
                     SRHALRSSFGMVLQDTWIKSGTVRDNICFGKPDATDEEIIRAAKEARSWEFIRRLPKGL
                     DTVLHEDSISQGQKQLLCITRVMLCLPPMLILDEATSSIDTRTELQVQEAFDKLMKGRT
                     SFIVAHRLSTIRNASLILVMKDGKIIEQGNHEELLKKGGFYHKLYHSQFEG"
     CDS             complement(8076..9956)
                     /note="MetaPbio_contig9a_70c--FOS"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q9WYC3|3.A.1.135.5"
                     /protein_id="CCG34779.1"
                     /translation="MKEMKRLEKFLRPYRRESILAPLFKLLEVVFDLMVPVVVAQIIDV
                     GVAKNDRGYIVEMFFVLLLMAAVGLLCSFTAQFFAAKASVGFATSVRQAMFDHIQRLSF
                     TELDTLGTDTLITRLTDDVNQVQNGINMGLRLLLRSPFVVIGAMVMAFTINVRCALIFV
                     VTVPILFVVVFSIMLISIPLFKKVQAGLDCVTGLTRENLTGVRVIRAFCREEQSVEEFE
                     EGNRELTRLNEFVGRISALLNPLTYVLINGATVLLIARAGVQVNIGNLQQGQVVALYNY
                     MAQIIVELIKLASLIITLNKSMACADRVAGILDVKSSMEYKVAAEQMKNEQINADQRKY
                     ETDGENDQADSNLAVEFNHVTFTYEGAGASSLSDITFRAKKGQTIGIIGGTGSGKSTLV
                     SLIPRFYDPQEGTVKVNGINAKDYPQGELCSEIGVVQQRSILFKGSIRDNLKWGNDQAS
                     DEDLWKAIIIAQAKDVVEAKPGKLDFEVEQNGRNLSGGQKQRLTIARALVSKPEILILD
                     DSLSALDFATDAALRKAIGELEGNVTTFLVSQRISGIRQADKILVMEDGELAGQGTHEE
                     LMETCETYQEIYYSQFPEERPAAVKSSKETGKDLDKADKMTEKAEKGAAE"
     CDS             10113..10955
                     /note="MetaPbio_contig9a_80--FOS"
                     /codon_start=1
                     /transl_table=11
                     /product="DBD-Pfam|HTH_1,DBD-SUPERFAMILY|0040266"
                     /protein_id="CCG34780.1"
                     /translation="MELRQLEYFREIASTGSINEAARHLNMSQPPLSYQIRQLENELNV
                     KLFDRTSKGVTLTEAGKLLYDRSGNLLEYARSTELEVSKTGKKRILRIGLTPTTVDTIM
                     PYISQFSKKNPDVNFEVHDGITYSLYQYLLDGIIDISVARTPLRLDEVSYMELCSEPMI
                     AVSAPENTASSLKLADLLHRPLILYRRYEELIMNTFHAQNMNPDIFCVCDDPRGAMLWA
                     KENLATAIFPQSMASLCDGLCIQELDEPDLVTKILLIWAKGKKPVPLVQEFLDVCGEH"
     CDS             complement(11357..11944)
                     /note="MetaPbio_contig9a_90c--FOS"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein DORLON_02268"
                     /protein_id="CCG34781.1"
                     /translation="MKMKSFEKFRKPLTSLMRFLEILHWFDGIVLLWAGSAIPMHSVHI
                     NGAIFGIKQDTMMNAYGMFFTLIDAKGNMRMHLVSVWLLLLGATSILLALIFRNVHKIL
                     KSLEGTKEQPEMGTPFTAENIERVKKIGIYSIVMPTIQNVVVYICGVLIKMNGLKDINF
                     EVRGFIFGIIVLCLAYVFSYGVNLQEEVDGFI"
     CDS             complement(11946..12173)
                     /note="MetaPbio_contig9a_100c--FOS"
                     /codon_start=1
                     /transl_table=11
                     /product="DBD-Pfam|HTH_3,DBD-SUPERFAMILY|0043143"
                     /protein_id="CCG34782.1"
                     /translation="MGIRICLDEVLKKKGMTSKELCRQVGITEANLSVLRSGKAKGIRL
                     HTMNRICYFLQCDVGDILKFDGNLDEEEGE"
     CDS             complement(12456..13859)
                     /note="MetaPbio_contig9a_110c--FOS"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|P50487|2.A.40.2.1"
                     /protein_id="CCG34783.1"
                     /translation="MESNKEEQITTVSEENIYKLNGRVPLRKAIPFGLQHVLAMFVSNL
                     APVLIVCSAAVLRSNGAHLSSAEITQLLQCAMFVAGIGTCLQLYPIGVIGSGLPIIMGV
                     SFTFLGSLLVIATNPNLGYEGMVGAVILGGIFEGFVGLSAKYWRKYLTPVVSACVVIAI
                     GLSLLPVGMDSWGGGSGVKDFGSWYHLVVGAFTLIVCLVSREVLKGVYKNLNVLVGLVF
                     GYALAIIFTVAGIAPMVDFSGIHKTIQEVGVFSIPKLVFLTSHKPVFNLGAFFTIAIVF
                     LVSAAETTGATTAVCTGALGRDLKMKELRGSLAVDGFSSAISGCFGCLPLTSFSQNIGL
                     VTMTQVINRFTILMGALILILASLFPPLGAFFNSLPQAVLGGCTVMMFGSIMYEGIKML
                     KECKFDDRTMIIVSLSFSIGVGLTQTSGNFFAAFPSAVGDVFNGNAVAGVFVVSLLLSL
                     FLPKKTKVE"
     CDS             complement(14002..14712)
                     /note="MetaPbio_contig9a_120c--FOS"
                     /codon_start=1
                     /transl_table=11
                     /product="putative transposase YhgA like"
                     /protein_id="CCG34784.1"
                     /translation="MAFIMDMNLYLYEHQSTYNPNIPLRNLFYIADEYQRLVVQKSLYS
                     TVIQKIPTPRFIVFYNGTKKVDDYNEFRLSSAYENPTDNPDLELRVTMLNVNDGHNLEL
                     MEHCRTLKEYAKYVARVRKYVTQNIPLEEAVTRAVDECIEEGILAEFLMKNKAEVIKVS
                     IYEYDKEFEEKKLRKAEYEAGVEAGIELGERSLLENQIRKKLKKGKPIEQIADELEEAV
                     TTIQRIIEETKKEN"
ORIGIN
        1 aagatcagtt cgaaacgctt gcgcaagcag gtgtgcgatc cgcattggaa ggcaagacaa
       61 ccctgcagga ggtgatgaac gatccttctt tccacaaatt attctgaatc cttctgactg
      121 acacctcaca caatcttgat taaatttact atgtaacctt aacacagttg cccaaattat
      181 gtcaatactg tcccggtcat ctgaattgaa acatccgctt cggaacagca aaaaaccctc
      241 gtccgactta atgtcaaaca agggtctctc gtacgtgcgc gagaagattc gaactcccga
      301 ccttctggtc cgtagccaga cgctctatcc agctgagcta cgcgcacata ttatatttgc
      361 ttgcctcagt tatttatgta cctcagcaac gaaattaatt atagcgcaac gttttctatc
      421 tgtcaacaac ttttttaaat ttttttaaat tattttttta aactctggtg gcctgcaagt
      481 cttccttttc tctggccgtt tctttcttct ttttataatg gtataattat tacatattta
      541 caatacatta gaaaatgagg atttctttat gacaaaaaaa gttgctgtaa tcaatgatct
      601 gtccggactt ggacgctgtt ccctgactgc tgccatctcc gtattatctg cgatgggaat
      661 ccaggcctgt ccactcccta ccgccatttt aagttcacaa acagaatacc ccagctacta
      721 ctgttatgat tttaccgata agatggatta tttccgccag gaatggaaga aactaggcac
      781 ttctttttcc ggaatctata ccggttatgt tgccagtgtc tgccagattg aacagatcat
      841 gcactttctg gatactttcc agacagcaga cacctttctt ctggtcgatc ctgtaatggg
      901 agacgatggc gttacctatg atatgtatac ttccgggctt ctgactgcta tgaaagaact
      961 tgccgcacgt gcagatgtta tcactcctaa ccttaccgaa ttctgtctgc tgacggatat
     1021 agattataac agcctgcagg atccgtctct gtctatacag cagctcattt cacgacttaa
     1081 ggatgcaggg cagactttga caaaggatca tgaaaaaaag gtcctcatca ctggtattca
     1141 ttttactgca gatgacggag ttcataagat tggaaatctc ctgctagatg gctcttcaca
     1201 ttttctttcg gcatatccct gttgcaacgg aagttattcc ggtacgggtg atctctttgc
     1261 ttcctgcatc acaggcggac ttgccagaga tatttccctt acggaaatga tgcagaccgc
     1321 aggttctttt cttgaaaaat cattaattga ttctgtagaa gaacatgttc cggtaaacga
     1381 aggcgttaat tttgaaaaat atttgtatct cttgcataca tagaacctac cactggcagc
     1441 ttctattgca tacattggta ttaaaaatca ccatatatct tttgaaaatt tctctactga
     1501 aactctttct tttgatatat ggtgatcttc tttctatatt attggtatct cagattgata
     1561 tttcgttaca taatttctga caacgtaatc tgtgctccca cagcttctgc ctgtaattta
     1621 taaacttccg gataatatct tgtcgaaaat acatattccc catcatttac aaatacttca
     1681 acagaggatg tatcggccag aatcttcaga ttctccactt cttccacttc tacatatctc
     1741 atgcttcttc cggaagatac cgaagtttta tcctgatctg taaaatgcat ccggaatttt
     1801 ccgtcagcat aatccaggat cagcttctct gaaaggataa ctttaaagcg gttctttgta
     1861 atatccgaaa tcgtcatttc atataccgga tatccctctc ctgccagcat acctttcaca
     1921 tcacttacca gatgtttctt ctcttctagt tctcttatcg gacgttgaca gatcttgccg
     1981 tctttttcaa agatttctct tggaaatgta aagcaatgct gccatcctgt ctgaatggtc
     2041 ggattgctgt attcttcgca gtccggcatt cccatccagc tgatgtggat ccttcttccg
     2101 tcttccgtct caaaactctg cggggcataa taatcaaacc cataatccca caaatgatac
     2161 tctgacaact tgtattctcc aagaatatct ccttctatct caaagtatcc ggactgatat
     2221 acattacgat cctcccagat accaccttcc agtccctgaa cagacgtgga aagaagtttc
     2281 ttatctccga ttttgaaata atccgggcat tcccacatat acccgaatgg cttttcggat
     2341 tccacccggt ttctgaactt ccagtttact ttatcttcag attcaaatac aagtacctga
     2401 cctacatctt tgttcgttct tgcaccctgt accatataat aagtaccatt ttctttccat
     2461 acctttggat ctcttacatg acaggtcaga tcgtccggat aatctgaatt tctcatcagt
     2521 tcttttttct ttccgaacgt cttgccgtct tccgttataa ccagaacggt attgccctca
     2581 cgtccggtgc ggatgtaatc atattccccg tcttctaatt tgacatttcc tgtatagtac
     2641 agatacattt ttccatcttc aataaatgcg gatccggaat atactccgtg acagtcaaat
     2701 ggctgatctg gataaagtgc ggtaccctga tattcccact taatcatatc cttgctggta
     2761 tagtgacccc acatcttcac accgccttct gcattaaacg gcgaatactg gaaaaacgcg
     2821 tgatagatac cctggaactg gcagagtcca tttggatcat tcagccagcc gaccggcggc
     2881 atcaggtgta gtttttcacg aaattttcta tctgatacgg ataactcttc tctggttttc
     2941 tggctttgtt ctgctgtctc tactaatttt acaagatctc ttgttaatgc gttcataaat
     3001 caatcgtctc catctatcta taagcattat ttctatacac attattttgt aagtgtcata
     3061 actttacttg ttgtcttaac ttcagcaggt tctgcctttg ttacatttcc gaattcatct
     3121 gtatttgtca gaatcatcat tgttgtcgtc tgatatcctg cattcttaat ttcctcaagg
     3181 tccgcttcta ccagaatatc tcctgcatgt actttgtcgc catcagaaac tttctttgta
     3241 aatccttttc catccatttt tacagtatca ataccgatat ggatcagaag ttcgccaccc
     3301 gattctgttg tgatacatac ggcatgacct gtctcgaaga tattcgatac ttctccgtcg
     3361 catggcgcta cgatttttcc gtctgcaggc tctactgcaa cggtagctcc gagcatctct
     3421 gatgcgaatg tctcatctgc tacttctgct aacggaatct gtgttccatt taccgggctt
     3481 gttaatgtct cttctgctgt ctctgcagtt gtgtctgctg ttgctactgc gtctgttgtt
     3541 tccatatttt ctactgctgc tgtctctgct gcatctgcgg ttgctgcctt tggttctgca
     3601 tccttataga tcaggaatga gatcacgaat gcaacaccga ctgcgatcac catctcgatc
     3661 aggtactgaa gcggctggtt caggcagagc aggataccga agatacctgt tacaccagtt
     3721 cctttcgctc caagatgtac cagtgatgca tataatgctc cacatcctcc accgatacat
     3781 ccggcgatga atggtttgaa gaatcttaag tttacaccga agattgcagg ctctgtaatt
     3841 cccataaatg cactgagtga tgatggaagc gccagagatt tgatcttctt atctttagac
     3901 ttaataccta ctgcaagtgc tgcagctccc tgtgctacgt tggctgcact tgcaagtgga
     3961 agccagtatg taacaccgta ttttgcaagc tgtccgatgt caatggctgt atacatctga
     4021 tgaataccgg ttactacggt tggtgcatat aaacctccca tgatcagact tccgattccg
     4081 agaggaagcg ttaacatcca ctggattgct ccgagaattg cattttcagc ccatacgaag
     4141 atcggtccta caattgataa tgtaaggtaa cctgttacaa atacgctgac cagaggtgtt
     4201 acgaacaagt caagaacttc cggaacgatc ttatgtaact tcttctcgat cactgccaga
     4261 atccatacgg cgatgataac cggaatgacg tgtccctgat atccgaccat gtcaatcttg
     4321 aacagtccga agaatacgct ctgtgtctgc tgtacaccct ctgttgctac agtataagca
     4381 ttctgcagtg acggatggat catgatcata ccgataactg caccaagata ctggttcgca
     4441 ccgaatgctt ttgcagctga gaatgcgatc aggatctgca ggaatgtgta agcaatgtta
     4501 ctgaacagat tcgcaaatac ataaatcgaa ctgtgtgtat taatatggag gaatccgttg
     4561 ctattcataa aatcaagtga gttcatgatt cccattaaga aaccgctggc tacgatggcc
     4621 ggaatgatcg gtacgaagat atcaccaagc agcttgatcg cacgcatgaa ccagttctgc
     4681 ttctctgcag ctgcctcttt tgcctctgct ttcgagcttg ccgtgatacc tgcgatgtcg
     4741 atgaactcgg caaatacttt atttactgta cctgttccga ggataatctg aagctgtccc
     4801 gatgcctcga agaccccttt taccccgtca atattttcaa gtgcttcttt acttactttc
     4861 ttattatctg caatgacaag acgaagtctc gttgcacaat gtgctgcaga tgcaatgttc
     4921 ttacttccgc cgacatgatc caggatgtcc tgtgcggtct ttctgtaatc catattaact
     4981 ctccttcctc attctatgtg taatcgtttt cacatcttgt aattttataa taagaaaaaa
     5041 atgccatttg taaagatggc atttttactg atatttgcta ttcgattttg tgcggtttgc
     5101 acgaattctg ttgtttttga ctgattcgga atctatttac acattttaca cactgatttt
     5161 ctgctccggc atctcttagt cttctatatt ttcttccgga tcatcaatgt tagcgagccg
     5221 gaatccaagt ttgatctcta ccggaatgct ttcatccctt tctattacat ccaacaggag
     5281 ttctgcgccc cggattccac tggtcttata gccaaaatgc actgttggta ttccacctgt
     5341 taccgccttt aaaagctgat tatcgccaaa tccggtaacc tgaatcgatg tattttctaa
     5401 tatataacgg aatctggatc ctgtgtcttc tacattcttc ggaatctgac ttccggcata
     5461 agtatgaatc gcttcgattg ccccggctgc gattgtatca gtggcgcatg atatgatatc
     5521 gatgtcatgt ttttcattca ataattccag aaccttttca tatccggatt ctgtcgtgaa
     5581 ctccgccacc ttataatatc cgtcttttaa ttcttttccc gaccttttca gaccttcccg
     5641 gaatccatct tctctggccg ctccagctgc tttatcttct cttgatactc cgatatatgc
     5701 aatctctttc cggctctttg ccgcaaccgc acatcccatg gcctcccctg cgccgtaatc
     5761 atcatgataa atacagttcg catatttcgt atgctgacca atcacaacca ccggtacttt
     5821 cgattctttc agaaatctcc ggtgttccgc cgtgatcatc gttcccacaa gaataatccc
     5881 gtctaccgga taattctcga acagacgcat atactctatt tccttcgccg gtgtattatc
     5941 cgttccggca agcagcatct ggtaattccg ctccgaaaga accttttcga ttcctgccgt
     6001 gatccggctg atggattctg aattaatctt tggtacaacc accccgatca gacacgcttt
     6061 cttggttcta agcatacgcg cctgcgccga tggctgatag ccggtctcat caattacttt
     6121 cttaatctgt tctttcttct cgtcactgac gtatccgccg ttcaggtatc tcgacaccgc
     6181 tgcgctggat actcctgcca gtttggcaat ttctttgatc gtcatatact gttactccct
     6241 ctgttcttct tcactgcaga atattataac acattccttc tacagatttt ctccattctt
     6301 actgattagt atttatctgt attataactg aaaaagcccg cctaagcgag ctttttgcca
     6361 gattgcgtat taaccttcaa actgactatg gtataactta tggtaaaatc cacctttttt
     6421 cagcaattct tcatgattgc cctgctcgat gatcttaccg tctttcataa ctaagattaa
     6481 cgaagcattc cgtatcgtcg aaagtctgtg tgccacgata aagcttgttc ttcctttcat
     6541 cagcttatcg aatgcttcct gtacctgcag ttcggtacgg gtatcgatac ttgatgtcgc
     6601 ctcatccagg atcaacatcg gcggcagaca gagcatgact cttgtgatac acagaagctg
     6661 cttctgaccc tggctgatac tgtcttcgtg aagcaccgtg tccagacctt ttggaagtct
     6721 ccggatgaat tcccagcttc ttgcctcctt cgctgcacga atgatctctt catcggttgc
     6781 atccggtttt ccaaagcaga tgttgtctct tacggttccg ctcttgatcc aggtatcctg
     6841 caacaccata ccaaagctgc ttctaagggc atgtctggat acctcccgga tgtcctttcc
     6901 atccaccagg atctttcctt catctacatc atagaagcgc atcagcaggt tgataaatgt
     6961 cgtcttaccg catcctgtcg gaccaacaat tgcaatacgc atacccggtt ttacatccag
     7021 attgaagttc tcgatcagtt ctttttcttt atcataacta aatgccacat cgtcgattgt
     7081 aacattgcca tcaactgtag caaatgcgcc ttccgcatcc aatgtctctt ctttctgctc
     7141 taacagatca aagatacggt ccgcacatgc cagcgcattc tgcatctctg tgactaccga
     7201 actgatatcg ttgaacggct tcatatactg gttcgcatac gctaacagta cagaaagtcc
     7261 tccgaccgtc agcgtgccgc ccggtatcag aaatgctcca agtaaagcca ctccggcgta
     7321 aatgatatta ttgacgaatc gtgtggacgg gttcgttaaa ctgctgtaga acactgcttt
     7381 ctggctgtag ttctgcagtt ctttattgat ttcatcaaat cttctggatg attctttctc
     7441 gtacccaaat gcttttacta ctttctgtcc gccgatcatt tcttcaatca gtgcggtctg
     7501 ccgtcctctg gtctcactct gcttccggaa catcgtataa gatctggaag aaatgaattt
     7561 cgccactacg aaactaaatg gtgtcagtac gatcaccagc agtgttaccc acacattctt
     7621 agagaacatg aaaatcagtg tcacaacaat cgtcacgatt cctgaaaaca actgtgtaaa
     7681 tcccaacaac agaccatcgg ataagatatc tgtatctgca atgacacggc ttacaatatc
     7741 tccggtgctg tgctgatcca gataagacaa cggcagtacc tggatatgac ggattgcctg
     7801 tgaacggata tcctgcacga tccggtaagt catccggttg ttcaacagat tcatgaacca
     7861 cgtagcaaat gctgatatca cgataaaaat cagaatctgc ttcagataat accacatcat
     7921 atcaaagttc acctgatgtg ccgatacaac ttcatcaatt gcatcaccga ataaaaccgg
     7981 cacatataac tgcaatacta cagagattgc agcaaagatt acactgaatg caaggaaaat
     8041 cttatacttt cctatgagct ttaataattt cttcattact ctgccgctcc tttctctgcc
     8101 ttctctgtca ttttatccgc tttgtccaaa tcttttccgg tttcctttga agatttaact
     8161 gcagccggac gttcttccgg gaactgtgaa taatagatct cctgataggt ctcgcaagtc
     8221 tccatcagtt cttcatgggt tccctgtcct gccagctcac cgtcctccat aaccaggatc
     8281 ttgtctgcct gacggatacc ggaaattctc tgagatacca ggaaggttgt cacattgcct
     8341 tccagttcac cgattgcttt acgaagcgct gcgtctgtcg caaaatccag cgcacttaag
     8401 ctgtcgtcca gaatcaatat ctcaggcttg ctgaccagtg cacgtgcgat cgtcagacgc
     8461 tgcttctgtc cgccggacag gttacgtccg ttctgttcta cttcaaaatc aagctttcca
     8521 ggcttagctt ctacaacatc ttttgcctga gcgattatga ttgctttcca cagatcttca
     8581 tctgaagcct gatcattgcc ccacttcaga ttgtcgcgga tacttccttt gaacaggatg
     8641 gaacgttgct gtaccactcc gatctcactg caaagttctc cctgcggata gtcctttgca
     8701 ttgataccat ttacttttac cgttccttcc tgtggatcat agaatctcgg aatcaggctg
     8761 accagtgtac tcttaccact tccggttcct ccgatgattc cgatcgtctg tcctttcttc
     8821 gcacggaagg tgatgtccga taagctggat gctccggcac cttcgtatgt gaaggtgacg
     8881 tggttgaatt caactgccag attactgtcg gcctgatcat tctcgccgtc tgtctcatat
     8941 tttctttgat cagcatttat ctgttcattc ttcatctgct cagccgccac tttgtattcc
     9001 atgctggact tcacatccag aataccggcc acacggtctg cgcaagccat tgatttgttc
     9061 aacgtaatga tcagggatgc cagcttgatc agttctacga taatctgtgc catatagtta
     9121 tacagcgcta ctacctgtcc ctgctgcaga ttcccgatat tgacctgcac tccggcacgc
     9181 gcgatcagta acacagttgc tccgttaatc aatacatacg tgagcggatt cagaagggca
     9241 gaaattcttc ctacgaactc attcaatctt gtaagttctc tgtttccttc ttcgaattct
     9301 tccaccgact gttcttccct gcagaatgca cggatgacac ggacacctgt cagattctct
     9361 ctcgtaagtc ctgtcacaca gtccagacct gcctgtactt tcttgaacag cggaatactg
     9421 atcagcataa tcgaaaatac aacgacaaac aggatcggta ctgtcactac aaagatcagt
     9481 gcacagcgta cattgatggt aaatgccatc accatcgcac cgattacgac aaacggactt
     9541 ctaagtaaca gacgcagtcc catgttaatt ccgttctgca cctggttcac atcgtccgtc
     9601 agtctcgtga tcagtgtgtc tgttccgagc gtatccagtt ctgtaaatga cagtctctgg
     9661 atatgatcga acattgcctg tctgacactg gtcgcaaatc cgacacttgc ctttgcggca
     9721 aagaactgtg cggtaaagct gcacaacagt ccgactgctg ccatgagtag taatacgaag
     9781 aacatttcca cgatatatcc acggtcattc ttcgcaacgc ccacatcaat gatctgagct
     9841 accacaaccg gaaccataag atcgaatacc acttctaata atttaaaaag cggtgccaga
     9901 atgctttccc tgcggtatgg cctcagaaat ttctcaagac gcttcatttc tttcactcca
     9961 ttcctttttc tatccgataa ctaataaatc atctgttatc tacttatcat aatgtccctt
    10021 gactgtttta ttatagtccg ttatcattga tatgaataat attgttttta tagctttgca
    10081 atacaaaaaa tatataagga aggtaatcca acatggaact cagacagtta gaatatttcc
    10141 gcgagattgc atccaccggc agcatcaacg aagctgcaag acacttaaac atgtcccagc
    10201 cgccgctcag ctatcagatc cgccagttgg aaaatgaatt aaatgtaaaa cttttcgacc
    10261 gcaccagcaa gggtgttacc ctgactgaag ccggcaagct tctctacgac cgctccggta
    10321 acctgctgga atacgcaagg tctaccgaac tggaagtctc aaaaaccggc aaaaaacgta
    10381 tcttacgtat cggcctgact ccgacaacgg tagataccat catgccttat atttcccagt
    10441 tttcgaaaaa aaatcccgac gtgaactttg aagtccacga cgggatcact tattcgcttt
    10501 atcagtatct tctggacggg atcatcgata tctccgttgc cagaacacca ctgcgtcttg
    10561 acgaggtgtc ttatatggaa ttgtgttctg agccgatgat cgcggtatct gcgccagaaa
    10621 atactgcctc ttccttaaaa ctcgctgatc ttctacacag acccttaatc ttatatcgaa
    10681 gatacgaaga actcatcatg aatacctttc atgcccagaa tatgaatccg gacatcttct
    10741 gtgtctgcga cgatccgaga ggtgcaatgc tctgggcaaa ggaaaatctt gcgactgcca
    10801 tctttccaca gtccatggca agcttgtgtg atggcctttg tatacaagaa ttggatgagc
    10861 cagatcttgt aaccaagatt cttctgatct gggcgaaggg aaagaaaccg gtgccgctgg
    10921 tgcaggaatt tctggatgtg tgtggtgagc attagcacat tagagcttgc ggctcaccca
    10981 ccatatacca attataagat ataccgccat cattcctaat atggcagatg ttgcaaccag
    11041 ttgattcata ttttccaaag caactactaa cagcagaagt acaatttcgc cacaccaata
    11101 ggaccagata catttccttt ttccgtaatc agtaatccaa gttttggaat ccacgatcca
    11161 gagtaaattg atgaatattc caaaaccaat agatacaatt agagaagtgg ccgcttccgc
    11221 tgacatattt atcattccat tttttacaaa tacaatacat aacaccaata aatcatacgc
    11281 caataacaat atgccatttc ttttcaatga tttgatactt ttctgcatat ctatctctcc
    11341 tctccaaata gaaatcttag ataaacccat ctacttcttc ctgcagattt actccataag
    11401 agaatacata ggctaaacat aaaacaataa ttccaaaaat gaatcctctc acttcaaaat
    11461 tgatatcttt cagtccattc attttaatca atactccgca aatataaacg accacattct
    11521 gaatcgtcgg cattactata ctgtaaattc ctattttctt tactctttct atattttctg
    11581 ctgtaaacgg tgtgcccatt tctggttgtt cctttgtgcc ttccagtgac ttcagtattt
    11641 tatgaacgtt gcgaaaaatc agggccagta atatagatgt tgctcccaac agcagaagcc
    11701 acacggatac cagatgcatc cgcatatttc cctttgcatc aatcagtgta aagaacatcc
    11761 cgtaggcatt catcatggta tcctgtttga tgccgaatat agccccgtta atgtgcacgc
    11821 tgtgcatagg tatagccgat cccgcccaaa gtaatacgat accatcgaac caatgtaaga
    11881 tttccagaaa tctcatcaga ctggtcagtg gtttccggaa tttttcaaaa cttttcatct
    11941 tcatattatt caccctcctc ttcatccaga tttccatcaa attttaaaat atcacctaca
    12001 tcacattgaa ggaaataaca gatacgattc atcgtatgca aacggatacc tttggctttt
    12061 ccgcttcgga gtaccgacag attggcctcg gtaataccga cttgtctgca taattctttt
    12121 gaagtcattc ccttcttttt caggacttca tccaagcata tacgaattcc catatttcct
    12181 cctttctgtg tttgaaaatt attgtttttc gataatttat aattttatta tagcaaggaa
    12241 ttatcgtttg tcaataattt ttaccacgca atattccaac cgtttttttc gtaattatgt
    12301 gatttttcca acttttctta tatttttaac tctaaagaat cttctttcgg caactactta
    12361 taaacgcatg gccccaaaaa aagattatcc ggatagttcc ctttctccag ataatctttt
    12421 cttctatgat tcactatgct gttttatatt ctcgcttact ccactttcgt cttcttcggc
    12481 aaaaacagac tcaaaagtaa cgataccaca aacactcctg ccactgcatt tccattaaac
    12541 acatctccta ccgcacttgg aaatgctgca aagaagttcc cggatgtctg tgtcagacca
    12601 actccgatac taaatgacag tgacacgata atcattgttc tgtcatcgaa tttacattct
    12661 ttcagcatct tgattccttc atacatgatc gatccaaaca tcataactgt acatccgcca
    12721 agcaccgcct gtggaagtga attgaagaat gctccaagcg gcgggaataa agatgcaagt
    12781 atcagaatca gtgctcccat cagaatcgta aaacggttga tcacctgtgt catcgtcaca
    12841 agtccgatat tctgactgaa tgatgtcagc ggcagacatc cgaaacatcc ggagattgca
    12901 cttgaaaatc catcaactgc cagtgaaccg cgaagttctt tcatcttaag atcacgtcca
    12961 agtgctcccg tacagactgc cgtcgttgca cctgtcgtct ctgctgccga taccaggaat
    13021 acgattgcga tcgtaaaaaa tgctcccaga ttgaataccg gcttatgact ggtcaggaac
    13081 acaagcttcg ggatactgaa cacaccaacc tcctgaatcg tcttatgaat accggaaaag
    13141 tcaaccatcg gtgcgattcc cgctacagta aatataattg caagtgcata gccaaatacc
    13201 agtccgacca gcacatttaa attcttatat acgcctttta gtacttctct ggataccaga
    13261 catacgatca atgtaaatgc tccaacgacc agatgatacc aggaaccgaa gtctttcact
    13321 ccacttccgc cgccccagga atccatacct accggcagaa gtgataatcc aatcgcgata
    13381 actacacaag ccgatacaac cggagtcaga tattttctcc agtacttggc actcagtcca
    13441 acaaaacctt caaaaatacc acccagaata actgcaccaa ccataccttc atatccaaga
    13501 ttcggattcg ttgcaattac caacagactt ccaagaaacg taaaactgac tcccataata
    13561 atcggaagtc ctgatccgat cactccaatc ggatataact gtaaacaggt tccgattccg
    13621 gctacaaaca tcgcacactg caataactgt gtaatctccg ccgaacttaa atgcgcccca
    13681 ttacttctaa gtactgccgc actacacacg atcagtaccg gagccagatt cgatacgaac
    13741 atcgccagta catgctgtaa gccaaacgga atggcttttc taagtggaac cctgccgttc
    13801 agcttataaa tattctcttc actgaccgtc gttatctgtt cttctttgtt gctttccatg
    13861 acatttcctc attctctctg taaaatttta tttattataa atttaactta tattttacga
    13921 gaaagcaacc gtggaagtaa taaatccatt tattactttt aaaagaagac tattgcactg
    13981 caacagcctt cctgattttg ctcaattttc tttttttgtt tcttctataa ttcgttgaat
    14041 tgtagttacc gcttcctcca attcatccgc aatttgttct ataggctttc cttttttcaa
    14101 cttctttcta atctgatttt ccagaagact ccgttctcca agttcaattc cagcttctac
    14161 cccagcctca tactccgctt tccgtaattt tttctcttca aattctttat catactcata
    14221 gatgctcact ttgatcacct cagccttatt cttcatcaaa aattctgcca gaattccttc
    14281 ctctatgcat tcatctaccg ctcgcgtaac tgcttcttcc agaggaatat tctgcgtcac
    14341 atattttctt accctcgcaa catatttagc atattccttt aatgttctgc agtgttccat
    14401 cagttctaga ttatgaccat catttacatt caacatagtc acccttaatt ccagatccgg
    14461 attatccgtc gggttctcat aagctgaaga taatcggaat tcattataat cgtctacctt
    14521 tttcgtccca ttataaaaca caataaatct tggtgtcggt atcttttgta ttaccgttga
    14581 atataaagat ttctgaacta ctaatctttg atattcatcc gcaatataga ataaatttct
    14641 aagcggaata ttcgggttat acgtcgactg gtgctcatac aaatataaat tcatatccat
    14701 aataaatgcc agat
//
