LOCUS       NC_013199              16781 bp    DNA     linear   CON 17-FEB-2020
DEFINITION  Lactobacillus rhamnosus Lc 705, complete sequence.
ACCESSION   NC_013199
VERSION     NC_013199.1
DBLINK      BioProject: PRJNA224116
            BioSample: SAMEA2272728
            Assembly: GCF_000026525.1
KEYWORDS    RefSeq; complete genome.
SOURCE      Lactobacillus rhamnosus Lc 705
  ORGANISM  Lactobacillus rhamnosus Lc 705
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
            Lactobacillus.
REFERENCE   1
  AUTHORS   Kankainen,M., Paulin,L., Tynkkynen,S., von Ossowski,I., Reunanen,J.,
            Partanen,P., Satokari,R., Vesterlund,S., Hendrickx,A.P., Lebeer,S.,
            De Keersmaecker,S.C., Vanderleyden,J., Hamalainen,T., Laukkanen,S.,
            Salovuori,N., Ritari,J., Alatalo,E., Korpela,R.,
            Mattila-Sandholm,T., Lassig,A., Hatakka,K., Kinnunen,K.T.,
            Karjalainen,H., Saxelin,M., Laakso,K., Surakka,A., Palva,A.,
            Salusjarvi,T., Auvinen,P. and de Vos,W.M.
  TITLE     Comparative genomic analysis of Lactobacillus rhamnosus GG reveals
            pili containing a human- mucus binding protein
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 106 (40), 17193-17198 (2009)
   PUBMED   19805152
REFERENCE   2  (bases 1 to 16781)
  AUTHORS   Paulin,L.G.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-JUL-2008) Paulin L.G., Institute of Biotechnology,
            University of Helsinki, PObox 56 (Viikinkaari 4), 00014 Helsinki,
            FINLAND
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/17/2020 14:47:54
            Annotation Pipeline               :: NCBI Prokaryotic Genome
            Annotation Method                 :: Best-placed reference protein
            Annotation Software revision      :: 4.11
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
            Genes (total)                     :: 2,921
            CDSs (total)                      :: 2,842
            Genes (coding)                    :: 2,714
            CDSs (with protein)               :: 2,714
            Genes (RNA)                       :: 79
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 92 of 128
            Pseudo Genes (incomplete)         :: 24 of 128
            Pseudo Genes (internal stop)      :: 21 of 128
            Pseudo Genes (multiple problems)  :: 8 of 128
            ##Genome-Annotation-Data-END##
            REFSEQ INFORMATION: The reference sequence was derived from
            FM179323.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotation Pipeline (PGAP)
            set; GeneMarkS-2+
            repeat_region
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..16781
                     /organism="Lactobacillus rhamnosus Lc 705"
                     /mol_type="genomic DNA"
                     /strain="Lc 705"
                     /db_xref="taxon:568704"
     gene            complement(1..939)
                     /locus_tag="LC705_RS12690"
                     /old_locus_tag="LC705_02681"
     CDS             complement(1..939)
                     /locus_tag="LC705_RS12690"
                     /old_locus_tag="LC705_02681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020752062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_014571673.1"
                     /translation="MILIVGCQTQKVKAADLKVADTPVPTRIYQMFLQDEKATTVNRYI
                     KQYHANYDKHFWKTKYNGKTPQQAAQNEALKKIKRFVIEDKALVKAGLIKRPFAEFERY
                     QKENQAGANLSGIAAAQKQHQGLMLKLESQYVQSHRKSVTINQKKDFYAKYKAKYWSVP
                     AIVHYEVLTFDRAKIKDINQFSEKVQQINGEHIDLKSIQNDFEEAGFKGQYNQTDSLHD
                     DNQYYGVYSRLASDHSNELDVIFPVWISEEKMGLLRIFSTEDGGFQPFSDVQDDVVTRL
                     LNDKLRRKISKTVQQVKIHIDQAALSKQALG"
     gene            complement(1059..2984)
                     /locus_tag="LC705_RS12695"
                     /old_locus_tag="LC705_02682"
     CDS             complement(1059..2984)
                     /locus_tag="LC705_RS12695"
                     /old_locus_tag="LC705_02682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015764761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PL12_1|PL12"
                     /protein_id="WP_015764761.1"
                     /translation="MAKMTWTTYIQQLRQHQHLTDHAQKNADRLLKNVYLFDNPYAMEP
                     TQISYTMDPIQWQKTPNGDPEWLYMLKRQEYLLDLLEAFYETGDMVYQKKMKALLFSWI
                     EENLAFPDTWRTIDTGIRLLNWTPVIANLLESQLLTAKERVNVESAVNTQAAYLKQNYT
                     EKFDISNWGILITTGILTYAAQFPNVIESDILHWAQKRFEVELDLQVDAQGMQWEQSPL
                     YLLEVWRSSLAVIAAQQRADLSVSPIVLAKTKAMHNMMAQYIKPNLKLLQQGDTDAIRI
                     DSLYQASVAILKLPSALSKQLDPVFDFGLLELAHEQWQLTTSEAVLPKQFDAPISGNYF
                     WRSGWDKQADYWHLFNGNLGSGHGHAALGHLDLTIGGQDVLVDPGRYTYVDGTERRYLK
                     GVTAHNTVMLDHKAFSLPKDSWKYQYVSNPIANQSVKFARGQVVKAVFLDQSQEDSAII
                     TRFLIGLSEERLWLALDLISYPGQHSLQRFWQISPHLEVARNGDGYILGDSARFTTTES
                     QIRQSKQLFSPRYNELQHLTRLESETLFQDFTAQVAVFSAGDKVVKITPVSAKHSGEVE
                     EEVPQKLALGFRLDLGENRDYLITLQPENTILGRKLYWFDGTEAYGSLNIFSRQGHKVI
                     EHFQLL"
     gene            complement(2923..3270)
                     /locus_tag="LC705_RS12700"
                     /old_locus_tag="LC705_02683"
     CDS             complement(2923..3270)
                     /locus_tag="LC705_RS12700"
                     /old_locus_tag="LC705_02683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005690847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="WP_005690847.1"
                     /translation="MTLWQIVLAILVVVVFLLYLVAIPLAKQRAMKKQAAIVDQMHANL
                     KLGDQIVLIDGIVGTIRGLDQENVRVEIAVNTIINVKRMGIAGVTKEAKTDGENDLDHV
                     HSTVASASTPH"
     gene            complement(3270..3737)
                     /locus_tag="LC705_RS12705"
                     /old_locus_tag="LC705_02684"
     CDS             complement(3270..3737)
                     /locus_tag="LC705_RS12705"
                     /old_locus_tag="LC705_02684"
                     /EC_number="2.7.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005717674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="WP_005717674.1"
                     /translation="MNYAMAIVGHGRYPEGVLSALKLLIGTTEGMTAFNLDENTTHERF
                     EQCLNDFLKENKHAIIFADMTGGAPHQIVSRLIIEKNQPHQYIISSAPLNLILDLYAKN
                     MSGFEDNAIEETLRHTVELSKQLIEILPDRMKTNSTKVPIPNAAPDEGDGI"
     gene            complement(3823..4638)
                     /locus_tag="LC705_RS12710"
                     /old_locus_tag="LC705_02685"
     CDS             complement(3823..4638)
                     /locus_tag="LC705_RS12710"
                     /old_locus_tag="LC705_02685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019898856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q8DR74|4.A.6.1.14"
                     /protein_id="WP_005714176.1"
                     /translation="MASSRKPVLTKKDYLNSILRSYVLQNAQNYGTMQGTGMANSIMPQ
                     LRKIYKDDDAEFKRVTTSNLEFYNTNPQPYPFVTSIMLAMYDSGQDENDVRAIKFALMG
                     PLAGIGDALSQFGLAPLFSSIFASLALQGMTWAPIPFILCLFGITFGVRMLMGYLGWKV
                     GTSIIDTLSDRMAAIADVASMLGLTVIAGLSVSFVKVNLAWQYTQVIKGKTQVVAVQTI
                     LDKIMPFMLPIALTYFVYWLITKKKWTIYKIVILLFVAGVLLSVLGILK"
     gene            complement(4628..5440)
                     /locus_tag="LC705_RS12715"
                     /old_locus_tag="LC705_02686"
     CDS             complement(4628..5440)
                     /locus_tag="LC705_RS12715"
                     /old_locus_tag="LC705_02686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016364848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q8DR75|4.A.6.1.14"
                     /protein_id="WP_005690844.1"
                     /translation="MTYSILQALLVGLWAAFCFAGQQWGIYTNRALFISFGIGLILGDL
                     QTAVVFGATAELAFMGFGVGPGGSTPPNPLGPGVVGTIMAISIQGLKPAAALSLSYPFA
                     ILIPFVITFIFSVNANNLAWSRKAIEEGKYRKFHFLANTTLLGFILFAFCFGFAATLST
                     SALKVFVQAIPQWLISGLTVAGGLLPAVGFALIMSTMVKKEYIPALILGYVCVAYLKMP
                     VIGLAFAGAVLAFNNYYNGHRANKNQDQGSNTNNDSNNSDDGGIEDGI"
     gene            complement(5469..5969)
                     /locus_tag="LC705_RS12720"
                     /old_locus_tag="LC705_02687"
     CDS             complement(5469..5969)
                     /locus_tag="LC705_RS12720"
                     /old_locus_tag="LC705_02687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005690843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q8DR76|4.A.6.1.14"
                     /protein_id="WP_005690843.1"
                     /translation="MTEPNIKAVRLDERLIHGQGRLWISNLGVNLVIVANDEVATSHIQ
                     QQLMSSLMPESVGIRFFSLEETANKIFKASPRQTIFIIVKTAQDVLTLAEKGVPITELN
                     VGNIHMKEGKTRLTNFISVDASDLEALKTLHIKYHVNLNTRTTPLGNDVGSDFDLNDYV
                     TKH"
     gene            complement(5982..7160)
                     /locus_tag="LC705_RS12725"
                     /old_locus_tag="LC705_02688"
     CDS             complement(5982..7160)
                     /locus_tag="LC705_RS12725"
                     /old_locus_tag="LC705_02688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005717671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH88"
                     /protein_id="WP_005690842.1"
                     /translation="MRIEPLTDAQRFFNAGLVDKRMLTTALDNAIKHLDLNIKVMGENF
                     PEPSTIHNRYAPMKNIEWTSGFWTGMLWLAYEYTGSNHYRELAEKNVTSFSNRINQKIA
                     VDHHDLGFLYSPSVVSAYQLTGSSVAKRSGIKAADQLLTRFNEKGGFIQAWGKKGAKDE
                     NRLIIDALLNIPLLYWATRVTRDVKYQQIGDRHYQTALKTVFRSDGSTFHTYFFDDDGN
                     PLRGATRQGYSDDSDWARGQAWAIYGTALHYYDTHDKTTFDVFKAVTNFFLNRLPADHV
                     PYWDLIFQEGSDQSRDSSSAAIAVCGMHEMLKYIPESDPDKNVYRMAMHAQLKSLIQNY
                     AAPLDGQTGEPLLLHGVYSWHSGHGVDEGNLWGDYFYMEALIRFYKDWQLYW"
     gene            complement(7157..7987)
                     /locus_tag="LC705_RS12730"
                     /old_locus_tag="LC705_02689"
     CDS             complement(7157..7987)
                     /locus_tag="LC705_RS12730"
                     /old_locus_tag="LC705_02689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005714177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="WP_014571676.1"
                     /translation="MLISLISAKSRIDSDLRSDESDAELILDHLYVKGDYLEIAFEPQT
                     LPCFRWIQVDAALSPSLVYFTQTPWRYHIPTNYLRVTEPAHESIFPEMAFAGREHVIRI
                     WRPDVVDLKGERNLALNCHDQAADMGAFPHASANIETRHDPTFAARNAIDGYRLNHHHG
                     KFPYQSWGINQDPKASFEIDFGRNVNLDHAVITLRADFPHDSYWKQGTMTFSDGSQMVI
                     HFSKTDNQQTFTINKSNIRSIRLSELVKAEDDSPFPALTELEVYGSETFEEMKH"
     gene            8211..8978
                     /locus_tag="LC705_RS12735"
                     /old_locus_tag="LC705_02690"
     CDS             8211..8978
                     /locus_tag="LC705_RS12735"
                     /old_locus_tag="LC705_02690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005690838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DBD-Pfam|TrmB,DBD-SUPERFAMILY|0040266"
                     /protein_id="WP_005690838.1"
                     /translation="MNTGKEASKPYGTVLIKAKEILDFLLAANDPPTLSDISRGLHSPK
                     PTTLKILSTLETLGFVWRDTDSKRYFLGTHFIPYAQKALATFNIVNVARPFLEDLRDKT
                     EETINLGIERNNKIILVEKLESPRSIKLQSTIGGSMNLYSSAMGKAILATFSSKSLDSY
                     FKSTKMVPMTPHTITTPSKLQKDLNSIKELGVSVDNEENEEEVFCLGASIVRDGQLYGA
                     FSISAPKYRMPQERRSAFVRMLLDTKHAIESAI"
     gene            9210..10055
                     /gene="kduI"
                     /locus_tag="LC705_RS12740"
                     /old_locus_tag="LC705_02691"
     CDS             9210..10055
                     /gene="kduI"
                     /locus_tag="LC705_RS12740"
                     /old_locus_tag="LC705_02691"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005714178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="WP_005690836.1"
                     /translation="MSFSMVTRYAHSPEDIQHYDTSKLRHEFLMEKIFNPGDILLTYTY
                     NDRMIFGGVMPTDEPLEIKLSTELGVDFFLQRRELGIINIGGAGAITIDGRKDAMSNQD
                     GYYIGMGTQKVVFTSEDRDHPAKFYVVSTPAHKTYPNKKLPFATALAKPMGDQQHLNKR
                     TIYKYIDASQMDTCQLQMGYTVLEPGSSWNTMPAHTHARRMETYMYFNFADPETRVFHF
                     LGKPDETRHITLFNEQAVVNPSWSIHCGVGTTNYAFIWAMCGENQTYDDMDQVAMNELR
                     "
     gene            10089..10913
                     /gene="kduD"
                     /locus_tag="LC705_RS12745"
                     /old_locus_tag="LC705_02692"
     CDS             10089..10913
                     /gene="kduD"
                     /locus_tag="LC705_RS12745"
                     /old_locus_tag="LC705_02692"
                     /EC_number="1.1.1.127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005690834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase
                     KduD"
                     /protein_id="WP_005690834.1"
                     /translation="MSEIHQTEEEIRQHEEELDHFKMTQFNLNGKVAIITGGNTGLGQG
                     YAVAMAEAGADIFIPTFGRAEWDNTRRLIEKRGQKVAFMEVNLTEPGSAEKVVKEALKQ
                     MGHIDILVNNAGMIRRNPLLESKDKDWDQVIAINLSAVYHLSLEVSKVFAQQKSGKIIN
                     IGSMLSFQGGKYIPSYTASKHGVAGLTKAFASEMGPYNVQINAIAPGYIKTENTAPVRA
                     DKNRNDDILSRIPAGHWGEPYELMGIAVFLASDAANYINGAIIPVDGGFLVS"
     gene            11033..11686
                     /gene="eda"
                     /locus_tag="LC705_RS12750"
                     /old_locus_tag="LC705_02693"
     CDS             11033..11686
                     /gene="eda"
                     /locus_tag="LC705_RS12750"
                     /old_locus_tag="LC705_02693"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005690832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="WP_005690832.1"
                     /translation="MQKYTFLSRLINTGCVAVIRGENLQAAIRTCDAVIAGGITGIEFT
                     FTIPHADKALKELTEKYDSQKSIVIGAGTVLDAVTARLAILAGAKFIVSPSFNPDVAKI
                     CNLYAIPYTPGVFTPTEIQQALEAGVDLVKIFPGSVAGLPMIQALKGPFPTLAIMPTGG
                     VSLDNMEAWFSAGATLVGAGSNLVEAAAHGNFDQVTATALKYRKKVDQIKQSRR"
     gene            11691..12710
                     /locus_tag="LC705_RS12755"
                     /old_locus_tag="LC705_02694"
     CDS             11691..12710
                     /locus_tag="LC705_RS12755"
                     /old_locus_tag="LC705_02694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005717667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STP|PfkB"
                     /protein_id="WP_005690831.1"
                     /translation="MPTVLTFGETMLRLKPVDHQRIFQASNFEANYGGAEANAAVSLSL
                     LGDQVQYLTKLPDNPLGSTARNTIRSFGVNTTKILWGGNRLGIYFFEKGTSVRNTNVVY
                     DRAGSAFATVKASEFDWPSLLQDVDYFYFSGITPAIGSELQQAILDACRYCANHKITVV
                     CDMNFRGKMWTAETAQTYFKTVMPYINVCIANDEDFEATLGIKAFDGNMATGIDQIDDF
                     KRGMFEVINRWPNVHTVASVVRNIYSVEKSQWTGLLVQNDAAYQGPIFNMHVFEGVASG
                     DAFGAGLVHGFIEDFNPQKMIDYAISASVLKLTISGDLNLVTDKDINAIMNTSSGVNR"
     gene            complement(12827..13516)
                     /gene="rpiA"
                     /locus_tag="LC705_RS12760"
                     /old_locus_tag="LC705_02695"
     CDS             complement(12827..13516)
                     /gene="rpiA"
                     /locus_tag="LC705_RS12760"
                     /old_locus_tag="LC705_02695"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016388769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="WP_014571678.1"
                     /translation="MDQNKLKQEAAQRAAEFVEDGMTIGLGTGSTVFYLVEAIAKRIKE
                     EHLSLNGVATSIRTRKQAESLGIPMKELDGVDKIDLTIDGADEVDKHFQGIKGGGRSHL
                     IEKIVAINSARNIWIVDETKLVDTLGKFPLPLEVIPFGSGKLLQRLADEGLKPAYRLNE
                     DGSKALTDSKNYIIDLHLGRIEHPHLLAEWLNKQVGIVEHGLFLDLVKTVVVGTTHGPE
                     ILDAHRG"
     gene            complement(13722..16781)
                     /locus_tag="LC705_RS12765"
                     /old_locus_tag="LC705_02696"
     CDS             complement(13722..16781)
                     /locus_tag="LC705_RS12765"
                     /old_locus_tag="LC705_02696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014571679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PL8"
                     /protein_id="WP_014571679.1"
                     /translation="MKRCLFGVGAFVLALGMAVGLKVQAEIDPDTRVPNTVQRGSVQRT
                     LGQSDQNVDTGTNRTTADETQFSLMRSRWRNRLMARNPDLNNPNVNAYLIDLAGQSKTL
                     WNTMDRRPDRKRLWAKKSSDTTSADYTTTFTNIKLLTLGYYNPKSEQYQDPAVYRAILD
                     AIDFMINVKQYNGTFSTGNWWDWQIGAAQQLDDTLILLYDDLQQQDPQRLRRFVQPLLG
                     YAKDPNIQWPKYTATGANLTDISISVLASGLLLEDDHRVALVQANLPKAMGLVTAKDGI
                     YADGSFIQHTFFPYNGSYGNEMIKGIARISSTLVGTPWAISEVQFANVFNLIDKGFLQL
                     MVNGRMPSMVSGRSISRAPGTNPETTELETGKETLANLTLIAEAAPAGLKQKIYQAVAT
                     WVAQVGDYYNFFNNPRDYAALNGLKTALSQATAQENDQDSLNVYGSMDRVMQKTSKYAV
                     GLAMYSNRIANFEYGNTENAHAWHTADGMLYLYNRDFNQFGEGYWTTVDPYRLPGTTVD
                     TAPLADGAKSSSRSPQSWVGGATDGIVASVGMVLDKTNEGQNLKAMKSWFLLNDQIVNL
                     GAGISGTTKADIETILDQRQIDPLTTKITIDGHTYVNQETAKNWVNLNTNDPSNNVGYI
                     IAKDNDQVDISRATRTGSYKDINGYFPSDTVYRHHYVTLAAKHGSAVKDGKYEYVTVPG
                     ASDSTIAALAKKPKYQVLANTNEVQAIKTQDQIMANIWNKASLLGGLLEIDQPVSLIIK
                     DLGENTYQLTATDPRQSDDPINFNFKYPVHIRKKQADGFSVNQDLLTLKTKGLAGASRS
                     VVVTVDVPTDKAALEGLISHAENVRAIDYTPSSYKKLITVLASAKAVYANAAAKQVVVD
                     QAKAALEDALKKLVKVADTSALKTVLAIINKLKGEVYTSESWQKLQDALIFGKVTLKNV
                     ESTQETVDYATKLLVEAQRALIKKDVNEASKHGQTTRLGKNSEDSRHDPEKMPNTGEKG
                     NFIFIIIGFTIIVLTGIVMFVCEKRENQTN"
ORIGIN
        1 tcagcctaac gcttgtttcg acaaggcagc ttgatcaata tgaatcttga cttgttgcac
       61 tgtctttgaa atttttcttc gcaacttatc gttcaaaagc ctagttacaa catcatcttg
      121 cacgtcagaa aatggttgaa atccaccatc ttctgttgaa aaaattcgca aaagacccat
      181 cttttcttca gaaatccaga ctgggaaaat tacatctagc tcattactat gatccgaagc
      241 caagcgtgaa tatacgccgt aatattgatt atcatcatgt agcgagtcag tttggttata
      301 ctgacctttg aatccagctt cttcaaaatc attttgaata ctcttcagat caatatgttc
      361 cccattaatt tgctgaacct tctccgaaaa ttggttgata tctttaattt ttgcccgatc
      421 gaacgtcaaa acttcataat gcacgattgc gggaactgac cagtacttcg ctttatattt
      481 ggcataaaaa tcttttttct ggttaattgt taccgacttt cgatgtgatt gcacatactg
      541 tgattcaagc tttagcatca aaccctgatg ttgcttttgt gccgcagcta ttcctgaaag
      601 atttgcccca gcttgatttt ctttttggta tctttcaaac tccgcaaacg gtctttttat
      661 aagccctgct ttcaccaaag ctttatcttc aatcacaaaa cgcttaatct ttttcaatgc
      721 ttcattttgg gctgcttgtt gaggcgtttt gccgttatac ttggttttcc aaaaatgctt
      781 atcataattt gcatgatact gtttgatgta acgattcaca gtagtggcct tctcatcctg
      841 caaaaacatc tgatagattc ttgtcgggac aggcgtgtca gccaccttta aatctgctgc
      901 tttgaccttt tgcgtttggc aaccgactat caaaatcatt aagagacaaa gtgcaagaag
      961 ttttagactc actgcttttt tcgttgtgct ttcctcctct gtcgaatgag ttatgatcac
     1021 ttatcaagtc caccgaaatc tatccatagg cacaagccct ataacaattg aaaatgttcg
     1081 ataactttgt gaccctgtct tgaaaaaatg ttcaaacttc cgtatgcctc agtgccatca
     1141 aaccagtaaa gtttacgtcc tagaatggta ttttcgggtt gtaaagtgat taggtagtca
     1201 cggttttcac ccaaatccag tcgaaagccc aatgccaact tttgtggaac ttcttcctca
     1261 acttcaccag aatgcttggc tgagactggc gtaatcttaa cgactttatc tccggctgaa
     1321 aatacagcta cttgggctgt gaaatcctga aaaagggtct cactttctag tcgcgtcaaa
     1381 tgctgaagct cgttatatcg tggcgaaaaa agttgtttgc tttgcctaat ctggctttct
     1441 gttgtagtaa aacgggcact atctcccaaa atatacccat caccatttct tgccacttca
     1501 aggtgtgggg atatttgcca aaatcgctgt agggagtgtt ggcctggata actgattaag
     1561 tcaagagcaa gccacagcct ttcttcgctc aaaccgatga gaaaacgtgt gattatggcc
     1621 gaatcctctt gggactggtc gagaaaaacc gccttgacta cctgtcctct agcaaatttc
     1681 acactttgat tagctatggg attggagacg tattggtact tccatgaatc cttcggtaag
     1741 ctgaacgctt tgtgatccaa catcactgtg ttatgtgcgg taaccccttt caaataacgg
     1801 cgttcggttc catcaacgta tgtgtatcga cccggatcaa caagtacatc ctgaccaccg
     1861 atcgttaaat caagatgtcc cagtgctgca tgaccatgcc cgctgcctaa gttaccattg
     1921 aaaaggtgcc aataatctgc ttgcttatcc caaccggagc gccaaaagta attaccgcta
     1981 attggtgcat cgaattgttt aggtaaaact gcttcactag tagttaattg ccattgctca
     2041 tgagccaact ctaacaaccc aaagtcaaac acaggatcaa gttgtttcga caatgctgat
     2101 ggcagtttca ggattgctac tgaagcttga tacaaactat caattctaat tgcatcagta
     2161 tccccttgct gcaacaactt caagttcggt ttgatatact gcgccatcat gttgtgcatc
     2221 gctttcgttt tggctaatac gattggcgac actgataagt ctgcccgctg ctgtgccgca
     2281 ataacagcaa gtgaacttcg ccaaacttca agcaaatata atggcgactg ctcccactgc
     2341 atgccttggg cgtctacttg aagatccagt tctacttcaa accgcttttg agcccaatga
     2401 agaatatctg actcaatcac gtttggaaat tgagcagcat aggttaaaat acccgtagtg
     2461 atcaagatcc cccagttact gatgtcaaac ttttctgtat agttttgctt taaataggcg
     2521 gcttgagtat tcaccgcgct ttcaacgttc acccgctcct tcgcagtcag taactgactc
     2581 tccagaagat tggcaatcac gggggtccag ttcaacaatc gtattcctgt gtcgatcgtc
     2641 cgccaagtat caggaaatgc caagttttct tcaatccagc taaagagcag cgccttcatt
     2701 ttcttctgat ataccatgtc gccggtttca tagaaagctt ctaaaagatc aagcaaatat
     2761 tcttgtcgtt tcaacatata aagccattcc ggatcaccat tgggcgtttt ctgccactga
     2821 atcggatcca tcgtatagct gatttgcgta ggctccattg cataggggtt atcaaataaa
     2881 tagacattct tcaataatcg atcagcattt ttttgcgcat gatcagtgag gtgttgatgc
     2941 tgacgcaact gttgaatgta cgtggtccaa gtcattttcg ccatccgttt tggcctcctt
     3001 tgtcacgcca gcaatcccca tacgtttaac attaatgatg gtgttgacag caatttcaac
     3061 gcgcacgttt tcttgatcca atcccctaat tgtgcccacg atgccatcaa taagcacaat
     3121 ctgatcacct aactttaaat tagcatgcat ttgatcaaca attgctgcct gttttttcat
     3181 ggcacgctgc ttagcaagtg gaattgcaac gagatacagc agaaagacta cgacaactaa
     3241 tattgccaga acgatttgcc acaaagtcat caaataccat ccccttcatc tggggcggca
     3301 ttcggaatcg gtaccttcgt ggaattggtc ttcattctgt caggcaaaat ctcaatcagc
     3361 tgctttgaga gttctacagt gtgccgcagt gtctcctcaa ttgcattatc ctcaaatcca
     3421 ctcatattct ttgcatatag atcaagtatt aaatttaaag gcgcacttga aatgatatat
     3481 tgatgtggct gatttttctc aatgattagc cgggagacaa tctgatgcgg tgcaccccca
     3541 gtcatatctg caaatataat tgcgtgctta ttttctttaa ggaagtcatt caagcattgc
     3601 tcaaatcgtt catgggttgt gttttcgtct aggttaaagg cagtcattcc ctctgtcgtt
     3661 ccaatcaata atttcagtgc cgagagaacc ccctctgggt accgaccgtg cccgacaatt
     3721 gccattgcat aattcatttg ttcaacatcc tccatcttca tttggctaga cccaacgttt
     3781 ctaaaacagc cgtccacaat tgacggctga aaaatgcata aactacttta agattcccag
     3841 aaccgaaagt aagacacctg caacaaagag cagaataaca atcttgtaga tagtccattt
     3901 tttctttgta atcaaccaat aaacaaagta tgtcaacgca atcggcaaca taaatggcat
     3961 aatcttgtcg agaattgtct ggactgcaac tacttgtgtc tttcccttaa taacctgtgt
     4021 atattgccaa gccaagttaa cctttacaaa agaaactgac aagcctgcaa taaccgttaa
     4081 ccctaacatg cttgcaacat cggcaatggc agccatccga tctgataagg tatcaataat
     4141 gctggtacct actttccatc ccagatagcc catcaacatc cggactccga aagtgatacc
     4201 aaacaaacac agaatgaacg gaatcggtgc ccatgtcatg ccttgaagcg ccagcgatgc
     4261 aaagattgaa ctaaacaaag gtgctaatcc aaactgagaa agtgcatctc caataccagc
     4321 caagggtccc attaaagcga acttaatcgc tcgtacatca ttttcatctt ggccactatc
     4381 atacatagcc aacataatac tggtcacaaa tggataaggt tgtggatttg tgttataaaa
     4441 ttccaaattt gaggttgtaa ctcgtttaaa ctcagcgtca tcatctttat aaattttccg
     4501 aagttgtggc ataatgctat ttgccattcc ggttccctgc atcgtgccgt aattttgagc
     4561 gttttgtaac acataggacc ggagaatgga atttaagtaa tcttttttgg ttaaaaccgg
     4621 ttttcgacta gatgccatct tcaatacccc catcgtcact gttgttactg tcattatttg
     4681 tgtttgatcc ttggtcttgg tttttgttag cgcgatgtcc attatagtaa ttattaaagg
     4741 cgagaaccgc acccgcaaat gccaatccga ttaccggcat cttcaggtaa gcaacacaaa
     4801 cgtaaccaag gattaaagcc ggaatatatt ccttcttgac catcgtgctc ataataagtg
     4861 caaatccaac ggcaggaagc agaccacctg caacagtcaa gccactaatc agccactgag
     4921 gaattgcttg aacaaaaacc ttcaatgcac ttgtgcttaa cgtagcagca aagccaaaac
     4981 agaaagcgaa cagaataaac cctaacaagg tcgtgttggc aagaaagtga aacttgcgat
     5041 acttgccttc ttcaatagcc tttcgtgacc aagcaaggtt gttggcattg acagaaaaga
     5101 tgaatgtgat gacgaatggg attaaaattg caaacggata cgaaagtgat aaagcagcgg
     5161 ctggttttaa gccttgaatc gagatcgcca tgatagttcc aacaacacca gggcccaaag
     5221 gattaggcgg tgttgagcca ccaggtccta caccaaatcc cataaaggct aattcagcgg
     5281 ttgcaccaaa aacaacggcc gtctgtaagt cacccaaaat taaaccaatc ccgaatgata
     5341 tgaacaatgc acgattggta taaatccccc attgttggcc agcaaagcag aacgctgccc
     5401 aaaggcctac caaaagcgct tgcaaaatag aataggtcat gctctttccc cctcagttct
     5461 cattgacttc aatgcttagt tacataatcg tttaaatcaa aatcggaccc aacatcgtta
     5521 cctaatggcg ttgtacgcgt gtttagattg acatgatatt ttatgtgtag tgtcttcaaa
     5581 gcctcaagat cactagcatc tacagaaata aaattcgtaa ggcgcgtttt gccttccttc
     5641 atatgaatat tgccgacatt tagttccgtg attggcacac ctttttctgc aagtgttaaa
     5701 acatcctgag cggtcttaac aataatgaaa atcgtttgcc tcggtgaagc tttgaaaatt
     5761 ttattggccg tttcttcgag cgaaaagaaa cggataccga ccgattccgg cattaacgac
     5821 gacattaact gttgctgaat gtggctagta gctacctcgt cattagcaac tatgactaaa
     5881 ttaacgccaa gattagaaat ccagagacgt ccttgaccgt gaatgagtcg ctcgtcaagc
     5941 cttactgcct taatatttgg ttctgtcatc tttagttccc cctaccaata taattgccag
     6001 tctttataaa atctgatcaa cgcttccata taaaagtaat cgccccagag gttgccttca
     6061 tccacaccgt gcccggaatg ccaagagtaa acaccatgaa gcagcaaagg ctctcccgtt
     6121 tgtccgtcta atggtgcagc atagttttga atcaaagatt tgagctgagc atgcattgcc
     6181 attcgataaa cgtttttgtc cgggtcggac tcaggtatgt atttcaacat ttcatgcata
     6241 ccacacacag caattgccgc ggaagatgaa tccctacttt gatcacttcc ctcctgaaag
     6301 ataaggtccc agtatggtac gtgatccgcc ggcaaacgat taagaaaaaa gtttgtaacg
     6361 gccttaaaaa cgtcaaaagt agtcttgtca tgcgtgtcat aataatgcag cgccgttcca
     6421 taaattgccc aggcctggcc tcgtgcccaa tccgaatcat ctgaatagcc ttgccgagtc
     6481 gcaccgcgca acggattacc gtcgtcatcg aagaaataag tatgaaaagt agatccatct
     6541 gatcgaaaca ctgtctttaa agccgtttga tagtgtcgat ccccaatctg ttgatactta
     6601 acatcacgag taacgcgtgt tgcccagtac aaaagcggaa tattgagtag agcatcaata
     6661 atcagccggt tttcatcctt agcacccttt ttcccccatg cttgaataaa gccgcctttt
     6721 tcattgaagc gagtcaataa ttggtctgct gctttaatgc cagatctttt tgcgaccgaa
     6781 ctgcctgtta attgataagc gctgacgact gaaggcgagt acaaaaaccc tagatcatga
     6841 tgatcaacag ctatcttctg attaattcgg ttagaaaagc tagtgacatt cttttctgcc
     6901 agctctcgat aatgattact gccagtgtat tcatatgcca gccataacat gcccgtccaa
     6961 aaaccgcttg tccattcaat gtttttcatt ggcgcataac gattatgaat agtagatggt
     7021 tcaggaaaat tttcacccat tacttttatg tttaaatcta gatgtttaat tgcattatct
     7081 aaagctgttg ttaacatgcg cttatccacc aatccagcgt tgaaaaagcg ctgcgcatct
     7141 gttaagggtt ctattctcaa tgcttcatct cctcaaaggt ttcgctccca tatacttcaa
     7201 gttcggttag tgcaggaaaa ggcgaatcat cctctgcttt gactaactca gaaagtcgaa
     7261 ttgatctgat atttgattta ttgattgtaa aggtttgctg attatccgtc ttactgaaat
     7321 ggatcaccat ttgactacca tccgaaaacg tcatagttcc ttgtttccag taactatcat
     7381 gtggaaaatc agctctgagc gttataactg cgtgatctag attgacattg cgcccaaagt
     7441 caatttcaaa actggccttt gggtcttggt taattcccca cgattgatag ggaaattttc
     7501 cgtgatgatg attcaaccga tacccatcaa tggcatttcg agctgcaaac gttggatcat
     7561 gtcgcgtttc aatgttggca ctggcatgag gaaatgcgcc catatcagct gcctgatcat
     7621 gacagtttaa cgctaggttg cgttcaccct ttaaatcaac aacatcaggt cgccaaattc
     7681 ttataacatg ttcacgaccg gcaaaagcca tttctggaaa gatgctttca tgagccggtt
     7741 ctgtcacacg taaataattt gtcggaatgt gataacgcca aggagtttgt gtaaaataaa
     7801 ccagagaagg actcaaagcc gcatcaacct gaatccatct gaaacaaggt aacgtttgcg
     7861 gctcaaaagc aatctcaaga taatctcctt tcacatataa gtgatccaga atcagctcag
     7921 cgtctgattc gtcagaccgc aagtcactgt cgattcgcga tttagctgag atcaatgaaa
     7981 ttagcaatat ccctgttttc tcctttcctg tttctttata ataaactttg tttctttacc
     8041 ttacgcttgt atattagcgt gcacactttc cgctgtcaac gaaaaagtaa acgtattcac
     8101 aatatttttt ccttgggtat taaaaatatg ttattgcttt ctaggacagg cagcgtttag
     8161 aatgattata aatttctaaa taataaatca ctgtaatcgg aggttttact ttgaatactg
     8221 gtaaagaagc gtctaaacca tatggaaccg tcttaatcaa ggccaaggaa atcttggact
     8281 ttctgttggc agcaaatgat ccaccaactt tatctgatat cagtcgtggt ttacattcgc
     8341 caaaaccgac aaccttaaaa atcctgagca cacttgaaac gcttggcttt gtctggcgtg
     8401 ataccgactc taagcgttat tttttaggaa cacactttat accttacgcg cagaaagctc
     8461 tagcaacttt taacattgtc aatgttgcac gtcctttttt ggaggacctt cgtgacaaaa
     8521 ccgaggagac cattaatcta ggtattgagc gaaacaataa gatcatcctg gttgaaaagc
     8581 tagaaagccc tcgtagcatt aaactacaat caacgatcgg tggaagcatg aacctttatt
     8641 cctcagcaat gggtaaagca atccttgcca ccttttcgtc caaatcttta gacagttatt
     8701 tcaagtctac taagatggtc ccaatgacac cccacacgat cacaacacca tctaagcttc
     8761 aaaaggacct taactcgatt aaagaattag gcgtttctgt tgataatgaa gaaaacgaag
     8821 aggaggtctt ctgcctcggg gcgtcaattg ttcgtgatgg gcaactatac ggtgcgttta
     8881 gtattagcgc tcctaaatat cgtatgcctc aggaaagacg ttccgccttt gtcagaatgt
     8941 tattagatac aaaacatgca atcgaaagtg ctatttaacc attaacgctg ttatttgact
     9001 gcacattcgg tttccttcac cacactatct caggtaatag ttatcgacaa ggctgccaaa
     9061 ttcaacagcc cttttattaa gccaagaagg caagcatcaa attgaatttt ttcaatttga
     9121 tgcttgcctt cttcttgaaa acgttttata ttgttgtcgt agcataaagg aaatcaagtt
     9181 tctatataag aaatattgga gggatcattt tgagttttag catggtcaca cgttacgcac
     9241 atagtccaga agatattcag cattatgaca catccaagtt gcgccacgaa ttcctgatgg
     9301 aaaagatctt caatcccgga gatatcctac tcacttatac gtacaatgat cgaatgattt
     9361 tcggaggtgt catgccaaca gacgaaccac ttgaaattaa attatcaaca gaattaggtg
     9421 tggatttctt ccttcaacgg cgcgagttag ggatcatcaa tattggcggt gctggcgcaa
     9481 ttacaattga cggacggaag gatgccatgt ccaaccaaga tggttactac attggcatgg
     9541 gaacccaaaa agttgtcttt acttcggaag accgcgacca tcctgcgaag ttttacgtag
     9601 tttcaacgcc agcacataaa acctatccga ataaaaaact gccatttgct accgcacttg
     9661 cgaaaccaat gggcgatcag caacatctca ataaaagaac tatttacaaa tatattgacg
     9721 cttcgcaaat ggatacttgt caattacaaa tgggatatac cgtattagaa cccggctctt
     9781 cttggaatac gatgccggcc catacgcacg caagacgcat ggaaacatat atgtatttca
     9841 attttgccga tccagaaacg cgagtctttc actttttggg caagccggat gaaacacggc
     9901 atattacgct attcaacgaa caagctgttg ttaacccaag ttggtccatt cactgtgggg
     9961 ttggaaccac aaactatgcc ttcatttggg caatgtgtgg ggagaatcaa acatacgatg
    10021 acatggatca agtagcaatg aatgaattac gctaatcaag tgttatcaat tttgaaggag
    10081 tgcttaaaat gagtgaaatt caccaaactg aagaggaaat tcgtcaacat gaagaagaac
    10141 tggaccattt taagatgacc caatttaatc ttaatggtaa agtcgcaatt attacgggtg
    10201 gaaatacagg attaggtcaa ggttatgctg ttgcaatggc agaagccgga gcggatattt
    10261 tcattccaac ttttggccga gcagaatggg ataacacacg gcggttaatc gaaaaacgtg
    10321 gtcaaaaggt tgcgttcatg gaggttaatc taactgagcc aggaagtgct gaaaaagtcg
    10381 ttaaggaagc actaaagcag atgggccata tcgatatttt ggtcaacaat gcgggtatga
    10441 tccggcgtaa tccattatta gaatcaaaag acaaagactg ggatcaggtt atcgcgatta
    10501 atctcagcgc tgtgtaccat ttgtctctag aagtttcaaa agtattcgcc caacaaaagt
    10561 caggaaaaat catcaatatt ggctccatgc tctcgttcca aggcggtaag tatattccct
    10621 cttatactgc aagtaagcat ggtgttgccg gcttaacaaa ggcgtttgct tccgaaatgg
    10681 gtccttataa tgtgcagatt aacgctattg cacccggcta tattaagacg gaaaacacag
    10741 cacctgtgcg cgccgataag aaccgcaatg atgatattct tagtcgtatt cctgcgggac
    10801 attggggtga accctatgag ttaatgggga ttgcagtctt tctggcaagc gatgccgcaa
    10861 attacattaa tggtgccatc atccctgttg acggtggttt ccttgttagc tgatcatcac
    10921 tttactgttt gactctctat tacaaagctg acaatttacg cgagctccga ggcggcatat
    10981 tgtccatctc ggagctttcg ttgttatcct atagaaaaaa gaaggaggcc ccttgcaaaa
    11041 atacaccttt ctaagccggt taataaacac cggctgcgtt gccgttatcc ggggtgaaaa
    11101 cctgcaagct gcaatcagaa cttgtgatgc tgttatcgcc ggaggtatta ccggaattga
    11161 gtttacattc acaatccctc atgcagataa ggcactcaaa gaacttaccg aaaagtacga
    11221 ctctcagaaa agcatcgtca tcggtgcagg tactgttctt gatgcggtca ctgcacgttt
    11281 agccatcctt gctggtgcaa agttcattgt aagtccaagt ttcaacccgg atgtcgcaaa
    11341 aatatgtaat ctttatgcta tcccctatac accaggtgtc ttcacgccaa ctgaaattca
    11401 gcaggcactc gaagccggcg tagacctagt taaaatcttc ccaggcagtg tagctggact
    11461 gcctatgatt caagctttga agggcccatt tccaacactt gctatcatgc caactggcgg
    11521 cgtctctctc gataatatgg aagcttggtt tagtgctggt gctacgcttg tgggtgctgg
    11581 ttcaaatctc gtagaagccg ctgcccatgg taactttgat caagtcacag caactgctct
    11641 taaatatcgc aaaaaagttg atcaaatcaa acaatctagg agatgaaaaa atgccaactg
    11701 ttctaacttt tggagaaacg atgcttaggc tcaaaccagt tgaccatcaa cggatctttc
    11761 aagcatccaa ttttgaggca aactatggtg gcgcagaagc taatgctgct gtatcgcttt
    11821 ctttacttgg cgatcaagtg caatacctga ccaagcttcc tgacaatcca ttaggttcaa
    11881 ctgcacggaa tactattcgt agctttggcg tcaatacgac caaaattctt tggggcggta
    11941 atcgtctagg aatttacttc tttgaaaagg gtactagtgt ccgaaataca aatgtcgttt
    12001 acgatcgcgc gggaagtgct tttgcgactg tcaaggcatc tgagtttgac tggccatctc
    12061 tgcttcagga tgttgattat ttttattttt ccggaattac accagcaatc ggatcagaac
    12121 tgcaacaagc cattcttgat gcatgtcgct actgtgccaa tcacaagata accgtcgtct
    12181 gtgacatgaa cttccgtggg aaaatgtgga cagccgaaac agcacaaacc tatttcaaaa
    12241 cggtcatgcc ttatattaat gtttgtatcg ccaacgatga agactttgag gcaacattag
    12301 gaattaaagc ttttgatggt aacatggcca ctgggattga tcagattgac gattttaaac
    12361 gtggcatgtt cgaagtcatc aatcgctggc caaacgttca tacagttgcc agtgtggttc
    12421 gtaacatcta ctcagttgaa aagagccaat ggaccggact gctcgttcaa aatgacgcgg
    12481 catatcaggg accaattttt aacatgcatg tttttgaggg tgtcgcctct ggggatgctt
    12541 ttggcgcagg tcttgttcat ggtttcatag aagattttaa tccgcaaaaa atgatcgact
    12601 atgctatatc cgccagcgtc ctcaagctga ctattagtgg tgatttgaat ctcgtcactg
    12661 acaaagacat caatgcaatc atgaatacca gcagtggtgt gaatcgttga aaagatggag
    12721 tttcttacgt aaagtcgtca gcagtaggtt ttataagtag cgtttaaagg ttaaattggg
    12781 tagcaaaaaa cggtatctac ctttgggggg ataccgtttt tgagttctat ccacgatgag
    12841 catccaaaat ttccggacca tgcgttgttc cgacaaccac cgttttaacc agatcaagga
    12901 acaatccgtg ctcgacaatc ccaacctgct tattgagcca ttctgccaac aaatgcgggt
    12961 gttcgatccg gccaagatgc agatcgataa tgtaattctt agaatccgtc aaagctttgc
    13021 tgccatcctc attcaaacga taagctggtt tcaggccttc atccgccaac cgctgtaaca
    13081 gcttgccact accaaacgga atcacttcta gcggcaacgg aaactttcca agtgtgtcca
    13141 ccagtttggt ttcgtccacg atccaaatat tacgtgccga attaatcgca acaatttttt
    13201 cgatcagatg tgagcgcccg ccgcctttaa taccctgaaa atgcttgtcg acttcatcgg
    13261 caccgtcaat ggtgaggtca attttgtcaa ccccgtccag ttctttcatc gggatcccca
    13321 acgactccgc ctgtttccgc gtccgaatgc ttgtggccac accattcaga ctaagatgct
    13381 cctctttaat ccgctttgca atggcttcaa cgagataaaa aaccgtcgag cccgttccca
    13441 agccaattgt catcccgtct tcaacaaact ctgctgcccg ttgagcggct tcttgcttca
    13501 acttattctg gtccatggtt aaccatcctt ttcgctttat tatcttcatt ataatatgaa
    13561 ttgtggtgta gatggcgatt tgtgaagaaa acaacaaatt aaagttttca atttttccga
    13621 taaatctgct aattagcgaa agaaaacaga cactactgcg agtttataaa cggatgcttt
    13681 gcaattcttt tatactcacc acttatattt acccgttgca tctagttcgt ctggttctcc
    13741 cttttctcgc atacaaacat tacgatacca gtcagcacga taatggtaaa gccgattatg
    13801 atgaaaatga agttgccttt ctcaccggtg tttggcattt tttccggatc gtgacggcta
    13861 tcttcactat tcttgcctag tcttgttgtc tggccatgtt tgcttgcttc gttaacgtct
    13921 tttttaatca aagcacgttg cgcctcaact aacaatttgg tagcataatc aaccgtttct
    13981 tgagttgact ctacattctt gagtgtcact tttccaaata tcaaggcatc ctgaagcttc
    14041 tgccaactct cagatgtgta tacttcaccc ttaagcttat taatgatggc taagacggtt
    14101 ttaagtgcac tagtatcagc aactttcact aatttcttta acgcatcctc aagcgctgcc
    14161 tttgcttgat ccacaactac ttgttttgct gctgcattcg catagactgc ttttgcactt
    14221 gccagcacgg ttatcaactt tttataactg gaaggcgtat aatctattgc cctaacattt
    14281 tccgcatgtg agattaaccc ctccaaagca gccttatcag taggaacatc aaccgtaact
    14341 accacagaac gactagcacc ggccagtcct tttgtcttaa gcgtcagcaa atcctgattg
    14401 acagaaaaac catctgcctg ctttttgcga atgtgaacag gatatttgaa attgaagttg
    14461 attgggtcat cagactgtcg tggatcggta gccgttaatt ggtaagtatt ctcaccgaga
    14521 tcttttatga taagcgaaac cggttgatca atctcaagta atccaccaag taaactggcc
    14581 ttattccaaa tatttgccat aatctggtct tgagtcttaa tcgcctgtac ttcattagta
    14641 ttggccaaca cttgatactt tggtttttta gctaaggcgg caattgttga atcacttgcc
    14701 cctggaacgg tcacatattc atacttgcca tccttaactg cggagccatg tttagctgct
    14761 aacgtaacat aatgatgacg atagacagtg tcagacggaa aatagccatt gatgtcctta
    14821 taggaaccgg ttcttgttgc acgactaata tcaacttgat cattatcttt tgcaataata
    14881 taaccgacat tattgctcgg atcgttggtg ttcaaattca cccaattttt agccgtttct
    14941 tgatttacat acgtgtgtcc atctatggtg atcttagttg tcagtgggtc aatttggcgt
    15001 tgatcaagga ttgtttcaat atctgctttc gtcgtgccag agatacccgc gccaagattg
    15061 acaatttggt cattaagcaa aaaccacgat ttcattgctt ttaagttctg accttcattt
    15121 gtcttatcta acaccatccc tacgcttgcc acgatcccat ctgttgcacc accgacccat
    15181 gactgaggac ttctagaaga agacttggca ccgtctgcaa gtggtgccgt gtcaacagtt
    15241 gtaccaggta atcgataggg atcaactgtc gtccagtagc cctcaccaaa ttgattgaaa
    15301 tcgcgattat acaaatagag catcccatca gccgtatgcc aagcatgagc attttcagtg
    15361 ttaccatact cgaaattagc aattcgattt gaatacatag caagtccaac cgcgtatttt
    15421 gacgttttct gcatcacacg atccattgag ccatagacat tcaaagaatc ttgatcattt
    15481 tcttgtgcag ttgcttgact cagggctgtc ttcagtccat ttaaagccgc ataatctcga
    15541 gggttattaa agaagttata ataatccccc acctgcgcta cccaggttgc cactgcttgg
    15601 tagatttttt gttttaatcc cgctggtgcg gcttcagcaa ttaaggttaa gtttgctaaa
    15661 gtttccttcc ctgtctctag ttctgtagtc tcaggatttg tgccgggtgc gcgggaaata
    15721 cttcggcctg agaccataga cggcattcgc ccattgacca ttagttgaag aaagcctttg
    15781 tcgatcaaat taaaaacatt agcaaattga acttcactga ttgcccatgg tgttccgaca
    15841 agagtagacg aaatacgtgc aatccccttg atcatctcat ttccataact accattgtac
    15901 gggaaaaaag tgtgctgtat aaatgagcca tctgcataaa taccgtcctt agcggtaaca
    15961 agtcccatcg ctttaggtaa attggcttga accagtgcga cacgatgatc atcttccaac
    16021 aataagccgc tagcaagaac agaaattgaa atatcggtca aattagcccc agttgccgta
    16081 tattttggcc actgaatatt tggatctttt gcataaccca ataatggttg aacaaacctc
    16141 ctcaatcttt gaggatcctg ttgctgtaaa tcgtcataga gcaaaatcaa tgtatcatca
    16201 agttgttgag ctgctcctat ttgccaatcc caccagtttc cagttgaaaa ggttccattg
    16261 tactgcttga cgttgatcat aaagtcgatg gcatcaagaa tcgctcgata aacggcgggg
    16321 tcttgatact gctcactctt aggattgtag taaccaagtg tcagcaactt tatattagta
    16381 aaagtcgttg tataatcggc tgatgtcgta tccgaactct tcttggccca caaacgctta
    16441 cgatcagggc gtcgatccat cgtattccaa agtgtcttgc tttggcctgc taaatcgatt
    16501 aaatacgcat tgacattcgg attgtttagg tctggattcc ttgccattaa acggttgcgc
    16561 catcgtgaac gcattaaact gaactgggtc tcgtctgccg ttgttctatt ggtccctgtg
    16621 tcaacatttt ggtcagattg accaagagtt ctttgaacac ttccacgctg aacggtgtta
    16681 ggaactcgtg tatcagggtc aatttctgct tgaaccttca gaccaaccgc catccctaat
    16741 gcaagaacaa acgctccaac tccaaatagg caacgcttca t
//
