LOCUS       GG692714               19158 bp    DNA     linear   CON 12-MAR-2015
DEFINITION  Roseburia intestinalis L1-82 genomic scaffold Scfld1, whole genome
            shotgun sequence.
ACCESSION   GG692714
VERSION     GG692714.1
DBLINK      BioProject: PRJNA30005
            BioSample: SAMN00008856
KEYWORDS    WGS.
SOURCE      Roseburia intestinalis L1-82
  ORGANISM  Roseburia intestinalis L1-82
            Bacteria; Firmicutes; Clostridia; Clostridiales; Lachnospiraceae;
            Roseburia.
REFERENCE   1  (bases 1 to 19158)
  AUTHORS   Weinstock,G., Sodergren,E., Clifton,S., Fulton,L., Fulton,B.,
            Courtney,L., Fronick,C., Harrison,M., Strong,C., Farmer,C.,
            Delahaunty,K., Markovic,C., Hall,O., Minx,P., Tomlinson,C.,
            Mitreva,M., Nelson,J., Hou,S., Wollam,A., Pepin,K.H., Johnson,M.,
            Bhonagiri,V., Nash,W.E., Warren,W., Chinwalla,A., Mardis,E.R. and
            Wilson,R.K.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JUN-2009) Genome Sequencing Center, Washington
            University School of Medicine, 4444 Forest Park, St. Louis, MO
            63108, USA
COMMENT     Roseburia intestinalis L1-82 (GenBank Accession Number for 16S rDNA
            gene: AJ312385 is a member of the division Firmicutes in the domain
            bacteria and has been isolated from human feces. The sequenced
            strain was obtained from the laboratory of Prof. Harry Flint,
            Rowett Research Institute, Aberdeen, Scotland, UK
            (H.Flint@rowett.ac.uk).
            We have performed one round of automated sequence improvement
            (pre-finishing), along with manual improvement that includes
            breaking apart any mis-assembly, and making manual joins where
            possible. Manual edits also are made where the consensus appears to
            be incorrect. All low quality data on the ends of contigs is
            removed. Contigs are ordered and oriented where possible.
            This work was supported by the National Human Genome Research
            Institute and the NIH Roadmap Human Microbiome Project
            [http://nihroadmap.nih.gov/hmp/].
            This is a reference genome for the Human Microbiome Project. This
            project is co-owned with the Human Microbiome Project DACC.
            Genome Coverage: 15.8X
            Sequencing Technology: 454.
FEATURES             Location/Qualifiers
     source          1..19158
                     /organism="Roseburia intestinalis L1-82"
                     /mol_type="genomic DNA"
                     /submitter_seqid="Scfld1"
                     /strain="L1-82"
                     /type_material="type strain of Roseburia intestinalis"
                     /db_xref="taxon:536231"
     gene            complement(1..1569)
                     /gene="manA"
                     /locus_tag="ROSINTL182_05469"
     CDS             complement(1..1569)
                     /gene="manA"
                     /locus_tag="ROSINTL182_05469"
                     /EC_number="5.3.1.8"
                     /inference="protein motif:HMMPfam:IPR001250"
                     /inference="protein motif:HMMPfam:IPR001360"
                     /inference="protein motif:HMMTigr:IPR001250"
                     /note="KEGG: bli:BL00290 3.4e-83 manA; mannose-6-phosphate
                     isomerase K01809; Psort location: Cytoplasmic, score: 9.26"
                     /codon_start=1
                     /transl_table=11
                     /product="GH1"
                     /protein_id="EEV02612.1"
                     /db_xref="InterPro:IPR001250"
                     /db_xref="InterPro:IPR001360"
                     /translation="MDNWTWNVAWFSDPVFLGHYPKEGLEKFAQYLPEITEEDMKLIHQ
                     PLDFMGQNIYNGYYVRAGENGEPEFVDREPGFPKTGADWPVTPEAFYYGIKFLTERYPL
                     PLYITENGMSCHDNISADGRVHDPNRITFLDSYIGAMQRASDEGADVRGYFLWTFLDNF
                     EWSDGYKQRFGIIYVDFTTQQRIVKDSAFWYQKVIETNGGILSMNQANKDILFLDPVCT
                     HNIWGGTKLREEFGYPVEGDDIGECWGISAHPNGDGTVRSGAFSGMKLSAVWKEHPEVF
                     GNYDCDRFPLLTKIIDARDDLSIQVHPNDDYAKVHENGSFGKTECWYIMDAPEGATLVI
                     GHNAKTKEELSDMIHQGRWKEFIREIPVKKGDFIQIDPGTVHAIKGGLLILETQQNSDI
                     TYRVYDYDRLSNGKPRELHVEKSIDVITVPAKSVDDSVKSALNLPENQLNELYSCKYYT
                     IFKADVNGKMEFEQKYPFLLVSVLEGDGIVGSSPVKKGDHFILPNGYGKVEMQGKMSLI
                     VSTVK"
     gene            complement(1607..2305)
                     /locus_tag="ROSINTL182_05470"
     CDS             complement(1607..2305)
                     /locus_tag="ROSINTL182_05470"
                     /inference="protein motif:HMMPfam:IPR001360"
                     /note="KEGG: sde:Sde_3603 4.7e-54 TonB-like K01188; Psort
                     location: Cytoplasmic, score: 9.26"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q9UEF7|8.A.49.1.1"
                     /protein_id="EEV02613.1"
                     /db_xref="InterPro:IPR001360"
                     /translation="MFRDDFVWGVASSSYQVEGTDANDGRGKTVWDAFTEAGRIFENQN
                     AYTTCDHMHHYKEDYALMKNLGIKAYRFSLNWARILPEGTGRVNEKAIRMYRDMITCMK
                     ENGITPYITMFHWEFPQALYEKGGWLNPEVADWFGEYAKVVAERFSDICEYFITINEPQ
                     CVVGLGHLSGVHAPGVKMSIKDTFQIAHNLMKAHGQAVINLRKYAVRDIKVGYAPTGGV
                     AYPYTDKPED"
     gene            complement(2329..3447)
                     /locus_tag="ROSINTL182_05471"
     CDS             complement(2329..3447)
                     /locus_tag="ROSINTL182_05471"
                     /inference="protein motif:HMMPfam:IPR001087"
                     /note="KEGG: rba:RB11249 5.5e-13 similar to acyl-CoA
                     thioesterase I K01076"
                     /codon_start=1
                     /transl_table=11
                     /product="GDSL-like protein"
                     /protein_id="EEV02614.1"
                     /db_xref="InterPro:IPR001087"
                     /translation="MEYQIKYENGIANRGCLYRLKKVMDRAKAGEALNIAFLGGSITQG
                     SLSSKPELCYAYHVYEWWKKTFPQADFTYINAGIGGTTSQFGVARAEADLLSKEPDFVI
                     IEFSVNDDSTEHFMETYEGLVRKVYTSKTKPAVLLVHNVFYNNGANAQLMHGRIARHYN
                     LPAVSMQSTIYPEVVAGRIENREITPDDLHPNDAGHALVASVITYFLDKVKTEDATEQS
                     EPDYPAPLTKNTYEKSIRHQNSDENVVCHGFVADTSAQRDITDCFKHGWTASKKGDSIT
                     LDVEGCNISVQYRKSVKLPAPVAEIIVDGDAEHAVRLDANFDETWGDKLELDTILEHGE
                     NKVHKVEVRLTETHENDAVPFYLVSVIGSSEK"
     gene            complement(3486..>3758)
                     /locus_tag="ROSINTL182_05472"
     CDS             complement(3486..>3758)
                     /locus_tag="ROSINTL182_05472"
                     /note="KEGG: chu:CHU_0721 0.0040 hypothetical protein
                     K01238; Psort location: Cytoplasmic, score: 8.96"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="EEV02615.1"
                     /translation="KHYQAFIEKLMQLYPKAQIILATTILCHDKSWDRSIDEVCTRIGS
                     ERVHHFLYTKNGSGTPGHIRIPEAEQMSDELAAYINSLGDAVWES"
     gene            complement(<3859..4637)
                     /locus_tag="ROSINTL182_05473"
     CDS             complement(<3859..4637)
                     /locus_tag="ROSINTL182_05473"
                     /note="Psort location: Cytoplasmic, score: 8.96"
                     /codon_start=1
                     /transl_table=11
                     /product="CE2"
                     /protein_id="EEV02550.1"
                     /translation="MKRVMECPQNVHFIIMECPRSGQSAYIFNFWRETQNMIIKPDNEM
                     LSYSGRIDFDDRLAPVLVYACSSIGMKFAGTSLKAVIANHRSCWTNELGYFIDGEQKRF
                     TLSSDEEKKTYTLAEGLSEGTHELLLFKRMDSCHTFTFYGFEIDDGAEVLPLPEKPKRK
                     MEFFGDSVSCGEVSEAVAYVGKPDPEHDGEYSNSWYSYAWMTARKLNAQIHDTSQGGIS
                     LLDDTGWFAAPHYKGVESCYDKIEYHPDLGPTKQWDFS"
     gene            complement(4731..5753)
                     /locus_tag="ROSINTL182_05474"
     CDS             complement(4731..5753)
                     /locus_tag="ROSINTL182_05474"
                     /inference="protein motif:HMMPfam:IPR007184"
                     /codon_start=1
                     /transl_table=11
                     /product="GH130"
                     /protein_id="EEV02551.1"
                     /db_xref="InterPro:IPR007184"
                     /translation="MSKYKMISQPVPNVPWQERPENLTGAPVWRYNENPIIGRNPVKGV
                     ARIFNSAVMPYEDGFIGVFRGEQTNGIPYIYLGRSKDAIHWNFDENKINFVDEEGKPFM
                     PRYAYDPRLVKVEDTYYIIWCQDFYGAAIGMAKTTDFKTFTRIENPFLPFNRNAVLFPR
                     KINGNFMLLSRPSDSGHTPFGDIFVSESPDLTYWGKHRHVMGKGSEWWESLKIGGGAAP
                     IETSEGWLLFYHGVSGTCNGYVYSIGGAILDIDNPSIVKYRCETFLLTPEEWYEERGFV
                     PNVCFPCATIHDSESGKIAIYYGAADSYVGLAFTELDDIIDYIKENSVVTPEDTEIGRR
                     "
     gene            complement(5836..7029)
                     /locus_tag="ROSINTL182_05475"
     CDS             complement(5836..7029)
                     /locus_tag="ROSINTL182_05475"
                     /inference="protein motif:HMMPfam:IPR007184"
                     /codon_start=1
                     /transl_table=11
                     /product="GH130"
                     /protein_id="EEV02552.1"
                     /db_xref="InterPro:IPR007184"
                     /translation="MEIRRMLHERYYVEKEKQEKLLSRKNVKSDFYNGVYDRYEYPVLT
                     REHIPLTWRYDLNPETNPYFMERLGINAVMNSGAIELNGKYYLVARIEGNDRKSFFGVA
                     ESDNGIDGFRFWDYPILLPDTCPEETNVYDMRLTKHEDGYIYGVFCSESKDTTVNDLSA
                     AVAAAGIVRTKDLKNWERLPNLVTLNSPQQRNVVLHPEFVDGKYAFYTRPMDDFIETGS
                     GGGIGFGLCDDITHAVIDEEKMTSLRKYHTITEAKNGAGATPIKTDKGWIHIAHGVRNT
                     AAGLRYVIYAFATDLNDPSKVIAEPSGLLIGPRGEERVGDVSNVVFTNGAIVNENNEVF
                     IYYASSDTRMHVATTTVDKLVDYVFNTPQDPGRSVECVAQRCGLIEKNLEFLAKEDK"
     gene            complement(7058..8287)
                     /locus_tag="ROSINTL182_05476"
     CDS             complement(7058..8287)
                     /locus_tag="ROSINTL182_05476"
                     /EC_number="5.1.3.8"
                     /inference="protein motif:HMMPfam:IPR010819"
                     /note="KEGG: bth:BT0453 1.0e-11 N-acylglucosamine
                     2-epimerase K01787"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acylglucosamine 2-epimerase"
                     /protein_id="EEV02553.1"
                     /db_xref="InterPro:IPR010819"
                     /translation="MSELKELAAEAKHELLTHIIPFWRGMRDDKFGGYYGYLSYDLALD
                     EKAEKGCILNSRITWFFANAYLLYKDGGISEEECEAAGFKGEDLLAEAKHGYEFLREHC
                     IDKEYGGIFWSLNYDGTPLDTTKHTYNQAFCIYALSSYYDAVGDKEALELAFSLFDIIE
                     ERCTDEIGYLEAFTRDFKPESNEKLSENGVLADKTMNTLLHVFEAYTELYRVTKNEKVG
                     KRLMWIMDTFADKVYNPAKQRQEVFFDADYNTILDLHSYGHDIETAWLMDRGVDVLNNE
                     HYREKMTPITKTLTSRIYQVAFDGHSLANECDRGVVNAHRVWWVQAETVVGFLNGYERN
                     TGHSEYRDAALAEWEFIKTYVVDKRNGSEWFWEVNEDGSPILDRPIVEPWKCPYHNGRM
                     CIEVIRRIGA"
     gene            complement(8309..9184)
                     /locus_tag="ROSINTL182_05477"
     CDS             complement(8309..9184)
                     /locus_tag="ROSINTL182_05477"
                     /inference="protein motif:HMMPfam:IPR000515"
                     /note="Psort location: CytoplasmicMembrane, score: 10.00"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q8DT26|3.A.1.1.27"
                     /protein_id="EEV02554.1"
                     /db_xref="InterPro:IPR000515"
                     /translation="MRKHNVNVQKRKKHYTVGAILWLIVEYVSLIFFGLCAVVPVISCV
                     ITAFKTQEEYQTTNVMTLPKNWLNFDNFIKAFQTADMGRAFLNSVIVMVSVLVVSIVIG
                     TQLAYVLNRFKFPGNGLIRNLFLFASLLPAVAMQVTVYNIMTALHFVNHLYGYIILMCG
                     TDVISIYIFIQFMENIPISLDESAIIDGASYWTIYWKIMLPLLKPAIVTSCILKGVGVY
                     NEYYMANLYLMDKKLHTIATSLYTFVGPMGSQYNLICAGVIISLLPALIVFILCQKQIY
                     SGIAAGAVKG"
     gene            complement(9189..10214)
                     /locus_tag="ROSINTL182_05478"
     CDS             complement(9189..10214)
                     /locus_tag="ROSINTL182_05478"
                     /inference="protein motif:HMMPfam:IPR000515"
                     /note="Psort location: CytoplasmicMembrane, score: 10.00"
                     /codon_start=1
                     /transl_table=11
                     /product="gnl|TC-DB|Q9X9R6|3.A.1.1.23"
                     /protein_id="EEV02555.1"
                     /db_xref="InterPro:IPR000515"
                     /translation="MDGGIVDMEGKKPFSFTKWAKSRKGQQVIICVAFMTIPLLLLFVF
                     TYLPFAEMVKFSFYKMKYLTPVDQRKFVGFKNYIDVFRRDDCFGALKLSLYYMVGAIIQ
                     LVLALYLATILSFKVKGGNFFKGLMFFPYLISGIAIGFIFKFFYTRGFVFDTILQWCGF
                     KLDNLPYWLKDQSINNWSLVATSVWRYFGQNMVLFIGAIMSVDADLYEAAELDGANKFQ
                     QFKHIILPSIKTIITLNVILSITGSLSAFEQPYVITDGANGTGTYFVIMNEIAHVSQKV
                     GLASAMAVVLLLIIFACTILQKLFFKYIFRDAESEDESYKAKRARLKAEKQAKKAGKGV
                     A"
     gene            complement(10265..11734)
                     /locus_tag="ROSINTL182_05479"
     CDS             complement(10265..11734)
                     /locus_tag="ROSINTL182_05479"
                     /inference="protein motif:HMMPfam:IPR006059"
                     /codon_start=1
                     /transl_table=11
                     /product="STP|SBP_bac_1"
                     /protein_id="EEV02556.1"
                     /db_xref="InterPro:IPR006059"
                     /translation="MKLRKVLAVTLVAAMTMSMAACGGSNNTAGNGGTTDNNSAAADNS
                     TDASNDVAATESGDASTSADGSLSYADIKLGEDYTDLTATISLFNHRTDLESDDYNGTT
                     WKEYLAAFNEMYPNITVELTTDTNYADDALMHLQSGDYETVMMIPAVDKADLSNYFISY
                     GDLDTMKTQINYATTWEYGGQVYGVPSTATTQGIVYNKKVFEEAGVTELPKTPEEFIGA
                     LQKIKDNTDAIPLYTNYAAGWTMGAWDAYIGNNATGDNTYMNQKLVHTKDPFQNYGDDT
                     HAYAVYKILYDAVADGLIEDDFATTDWEGCKGMINNGEIGCMVLGSWAYPQMEAAGENG
                     ADIGYMPFPITVNGEQYASAGADYSYGINANATDDEKAAAMVFVKWMTEKSGFSYNEDG
                     LPVAAGSTDTKLSFDGVTFLEDEPALAGEEDFLNEMNAESELNINAGGDSKIQAIIEHA
                     SNGDKTFDEIMDEWNTAWSDAQESNGIEVTE"
     gene            complement(13099..14124)
                     /locus_tag="ROSINTL182_05480"
     CDS             complement(13099..14124)
                     /locus_tag="ROSINTL182_05480"
                     /inference="protein motif:HMMPfam:IPR000843"
                     /inference="protein motif:HMMPfam:IPR001761"
                     /note="KEGG: efa:EF1922 8.8e-07 transcriptional regulator,
                     LacI family/carbohydrate kinase, PfkB family protein
                     K00852; Psort location: Cytoplasmic, score: 9.97"
                     /codon_start=1
                     /transl_table=11
                     /product="DBD-Pfam|LacI,DBD-SUPERFAMILY|0036955"
                     /protein_id="EEV02557.1"
                     /db_xref="InterPro:IPR000843"
                     /db_xref="InterPro:IPR001761"
                     /translation="MAKAVKLADIAEQLGVSTVTVSKALSGQKGVSEAMREKIKQLADE
                     LGYKQPSAVKKEKSAKSYNIGVLVSEKYLGEYASFYWRMYQSVATRAVQKECFTMLEVV
                     SLEDEAEANLPKIVLERKVDGLILIGRLKTEYLGALRQNTQIPIVYLDFYDEHQMSDAV
                     ISNSYYGTYMLTNYLIEHGHEKIAYVGTLLFTASITDRYFGYRKSMLEHGIEVPQEWII
                     SDRDMECGVVKVDIHPDQMKDMPTAFVCNSDLTASMVINQLEEQGYRVPQDFSVVGFDN
                     YLFPGLCDVEITTYEVDIREMANKAIHVLLKKVGGERYKQGITIVEGRLVEKASVQQVV
                     K"
     gene            complement(14167..16356)
                     /locus_tag="ROSINTL182_05481"
     CDS             complement(14167..16356)
                     /locus_tag="ROSINTL182_05481"
                     /inference="protein motif:HMMPfam:IPR000111"
                     /note="KEGG: gka:GK2152 7.3e-200 alpha-galactosidase
                     K07407; Psort location: Cytoplasmic, score: 8.96"
                     /codon_start=1
                     /transl_table=11
                     /product="GH36"
                     /protein_id="EEV02558.1"
                     /db_xref="InterPro:IPR000111"
                     /translation="MAITYFEKERIFKLDTPASSYVIGIVDKENFVGHVYYGKKLRDAN
                     IAYLLRTGEGPFVPSENNRERVSFYDTFPMEYAGNGLGDYRRSSISVRTAGGHTAVSLF
                     YVSHKIYAGKPGLAGLPATFGDENACETLELLCEDPVLGLKVTLLYTAFSDVDVITRSV
                     RIENNGEMLYLTKALSCSMDMDNRDFTLLTMHGSWARERMLEHRKVKKGFMGVESVRGE
                     SSHQEHPFMALAAGNADQSQGEVYGMHFVYSGNFIGQVELGQFDTVRVGMGIHPENFCW
                     KLEKGESFQTPEVVLVYSDTGYDGMTHQFHELYRNHLIRSEYKDKKRPILINNWEATYF
                     DFNTEKLLSIAKKASELGIEMLVMDDGWFGHRNDDSSSLGDWYVNEEKLNGGLKHLVDE
                     VNKLGLKFGIWFEPEMISPDSKLYEAHPDWAIQIPGREGSLCRNQYVLDLTRKEVRDYA
                     YESVASILRSANIEYVKWDMNRQLSDIGSFGLPADRQGELYHRYVLAVYEMQERLVTEF
                     PHLLLENCSGGGARFDPGMLYYSPQIWCSDDTDAVERLKIQESTAMIYPLSTMGAHVSD
                     CPNHTVGRVTPFETRGHVALAGTFGYELDITKIPEEDRQMIPKQVAMYHKYNDLVRSGD
                     YYRIASYQENHYFDCYEVVSKDKSEALVTFVQVINRPNYKSRRITLKGLDPQKNYCLEG
                     EDTVYAGDTLMYAGILIQNPWGDFQSKLLHFVEKK"
     gene            complement(16373..18091)
                     /locus_tag="ROSINTL182_05482"
     CDS             complement(16373..18091)
                     /locus_tag="ROSINTL182_05482"
                     /inference="protein motif:HMMPfam:IPR005843"
                     /inference="protein motif:HMMPfam:IPR005844"
                     /inference="protein motif:HMMPfam:IPR005845"
                     /inference="protein motif:HMMPfam:IPR005846"
                     /note="KEGG: cpr:CPR_1841 2.1e-163 phosphomannomutase
                     K01840"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucomutase/phosphomannomutase,
                     alpha/beta/alpha domain II"
                     /protein_id="EEV02559.1"
                     /db_xref="InterPro:IPR005843"
                     /db_xref="InterPro:IPR005844"
                     /db_xref="InterPro:IPR005845"
                     /db_xref="InterPro:IPR005846"
                     /translation="MSNYMETYKQWCTDPYFDADTKAELKKIEGDQAEIEDRFYRQLEF
                     GTGGLRGVIGAGTNRMNIYTVRQATQGLANYIISQNGQEKGVAIAHDSRIMSPEFTEEA
                     ALCLNANGIKAYVFDSLRPTPELSFAVRELGCISGIVITASHNPREYNGYKVYWEDGAQ
                     ITPPHDKNILAEVAKVTSFDQVKTMAKEEAVAAGLYNVIGKEIDDRYMEELKKQSIHPE
                     IIKEMAKDIKIVYTPLHGTGNLPVRRVLKELGFEHVYVVPEQEKPDGNFPTVAYPNPES
                     PKAFELALKLAKEVDADIVLATDPDADRLGVYCKDTKSGEYVTFTGNMSGMLIAEYILR
                     EKTAMGTMPKNPALVETIVTTDMAKAIAKAYGVKLIEVLTGFKYIGEQIKFFEQQNTYD
                     YVFGLEESYGCLAGTYARDKDACVAVMMLCEVASWCKKNNMTLWDEMLAMYEKYGYYRE
                     GLETKTLKGIDGAAQIQELMSNSRKNPPKTLGGFDVLAVRDYKEDTRKDTVTGEVTKTG
                     LPESNVLYYELSDNAWCCMRPSGTEPKIKYYFGVKGSSLEDAEKKLAVLKEDLLK"
     gene            complement(18223..19158)
                     /locus_tag="ROSINTL182_05483"
     CDS             complement(18223..19158)
                     /locus_tag="ROSINTL182_05483"
                     /note="Psort location: Cytoplasmic, score: 8.96"
                     /codon_start=1
                     /transl_table=11
                     /product="GH113"
                     /protein_id="EEV02560.1"
                     /translation="MEYICGVTFAPFACAGAFFKPGAKESLAMMKERTGANFVIFVPGG
                     LQETPQSEEICFTSKATMEDDELIAMIEYAKEIGLRVALKPTVNCKNGTWRAHINFFDE
                     DVPCEPKWGNWFASYTAFQLHYAKIAEQHDCEMFIAGCEMVMSEHREAEWRKLLSDIRQ
                     VYHGLLSYNTDKYQEHRVNWWDAVDVISSSGYYPYGDWENQLDRIETVVNRFQKPFFFA
                     ETGCMSVKGSKEVPNDWCVRGDADPKGQAEWYEDMFTACSKRDWVGGMALWSWDAKLYQ
                     ERSAKTRMDYEIYAKPAEKVVKKYYDIFNK"
ORIGIN
        1 ttattttaca gtagaaacga tcagactcat cttcccctgc atctcaactt ttccataacc
       61 attcggcagg ataaaatgat ctcccttctt caccgggctg ctgcccacga ttccatctcc
      121 ctctaaaaca gatactaaca ggaacggata cttctgctca aattccatct ttccatttac
      181 atctgcctta aagatcgtat aatatttgca ggaatacagc tcattcaact gattttccgg
      241 cagattcagt gcggatttta cgctgtcatc cacagatttt gccggaactg tgatgacatc
      301 aatactcttt tccacatgaa gctctcttgg ctttccattc gagagacggt catagtcata
      361 aacacggtaa gtaatatcac tgttctgctg tgtctctaaa attaaaagtc cacccttgat
      421 tgcatgaacc gttcccggat cgatctggat aaaatcacct tttttcaccg gaatctcacg
      481 gataaattct ttccatcttc cctgatggat catatcggaa agttcttctt tcgtctttgc
      541 attatgtccg ataacaagtg ttgctccctc cggtgcatcc atgatatacc agcactccgt
      601 ctttccaaaa gaaccatttt catgcacttt tgcataatca tcatttggat gtacctggat
      661 acttaaatcg tctcttgcat caatgatctt cgtgagaagc gggaaacggt cacagtcgta
      721 attgccgaac acttccggat gttctttcca tacagcagat aacttcatgc cggaaaatgc
      781 gccgcttcga acggttccgt ctccgtttgg atgtgcggag atgccccagc actcgccgat
      841 gtcatcaccc tctaccggat agccgaactc ctctcttaac tttgtaccgc cccagatatt
      901 gtgcgtacat accgggtcta aaaataaaat atctttattt gcctgattca tactaagtat
      961 tcctccattc gtttctatta ctttctgata ccagaatgcc gaatccttta caatgcgctg
     1021 ctgcgttgta aagtctacat aaatgatacc aaaacgctgt ttgtatccat cggaccactc
     1081 aaaattatca agaaatgtcc acaggaaata tccccttaca tctgcacctt catcgcttgc
     1141 acgctgcatg gctccgatat aggaatccag aaacgtgata cggtttggat catgcaccct
     1201 gccatctgcg ctgatattat catgacagga catgccgttt tccgtgatgt aaagcggcaa
     1261 tggataacgc tctgtcagaa attttatacc ataataaaaa gcttccggcg ttaccggcca
     1321 gtctgctcct gtcttaggaa atcccggttc acggtccaca aattccggtt caccgttctc
     1381 tcctgcacgg acatagtaac cattgtatat attctgtccc ataaaatcaa gcggctgatg
     1441 gatcagcttc atatcttctt ccgtgatctc tggcagatac tgcgcaaatt tctccaatcc
     1501 ttctttcgga taatgcccta aaaatacagg atccgaaaac catgctacat tccaggtcca
     1561 gttatccatc ggattataga aaccaaaata tacttttttc gcagcttcag tcctccggtt
     1621 tatccgtata aggataagcg acacctccgg tcggtgcgta tccgactttg atatcccgga
     1681 ctgcatattt acgcagattg ataacagcct ggccatgtgc cttcatcaga ttgtgtgcga
     1741 tctggaaagt atctttgatt gacattttta ctcccggtgc atgtacaccg cttaaatgtc
     1801 caagtccaac cacacactgc ggttcattga tcgtgataaa gtattcacaa atatcggaaa
     1861 aacgctctgc aactaccttc gcatactcac caaaccagtc tgccacttcc gggttcagcc
     1921 agccaccctt ttcataaaga gcctgcggaa actcccagtg aaacatggta atatatggcg
     1981 taatcccatt ttctttcata catgtgatca tatcacggta catccggatc gctttttcat
     2041 tgacacgacc ggttccttcc ggcagaatac gtgcccagtt taatgaaaaa cgatatgcct
     2101 tgataccaag atttttcatc agcgcgtaat cttccttata atgatgcata tgatcacagg
     2161 tcgtataagc attctgattt tcgaaaatcc tgcctgcctc cgtaaatgca tcccagactg
     2221 tttttcctct tccatcgttt gcatcggttc cctctacctg ataggaactg ctcgcaacac
     2281 cccaaacaaa atcatcccga aacattcttc ttttcctttc ccagtgaatt atttttcaga
     2341 ggaaccaatg acagacacca gataaaatgg cactgcatca ttctcgtgtg tctctgtcag
     2401 acgcacctcc actttatgta ctttattttc gccatgttct aagatggtgt caagttctaa
     2461 tttatcaccc caggtctcat caaagttcgc atccagacgg actgcatgtt ctgcatcgcc
     2521 gtccacaatg atctctgcaa ccggtgccgg aagttttacg gattttctgt actgtactga
     2581 aatattgcag ccctcaacat caagtgtgat ggaatcacct ttctttgaag ctgtccatcc
     2641 gtgtttgaaa cagtcggtaa tatctctctg tgcggacgta tctgcgacaa atccatggca
     2701 gactacgttt tcgtcgctgt tctgatgacg gatggatttc tcataagtat tttttgtgag
     2761 aggtgccgga taatccggtt cgctctgttc cgttgcatct tctgttttta ctttatctaa
     2821 aaagtatgta atcaccgatg cgacaagtgc atgtccggca tcattcggat gcaggtcatc
     2881 cggtgtgatc tcacggtttt cgatgcgccc ggcgacaact tccgggtaga tcgtactctg
     2941 catgctgaca gccggaagat tataatgtct tgcaatgcgt ccgtgcatca gctgcgcatt
     3001 ggcaccgtta ttgtaaaata cgttgtgcac taaaaggact gccggttttg tcttactggt
     3061 atatactttt cgcaccagtc cctcataggt ctccataaag tgctccgtgc tgtcatcgtt
     3121 gacggaaaac tcgatgatga caaaatccgg ctctttggaa agcagatcag cttctgcgcg
     3181 cgccacacca aactgtgagg ttgttccgcc gattcctgca ttgatgtaag taaaatcagc
     3241 ctgtggaaat gtctttttcc accactcata gacatggtat gcgtaacaga gttccggttt
     3301 ggaagaaagg cttccctggg tgatcgagcc gcctaaaaat gcgatgttta aagcttcgcc
     3361 tgctttggcg cgatccatga cttttttcag gcggtataag cagccgcggt tggcaatgcc
     3421 gttttcgtat ttaatttgat attccatttg atgttctctc cttttttgct gtttccggtg
     3481 caaaactaag attcccagac tgcatcccct aatgagttga tatacgccgc aagctcatcc
     3541 gacatctgct ctgcttccgg gatgcggatg tgtcccggcg tgccggagcc attttttgtg
     3601 tagagaaaat gatggactct ctcactgcca atgcgtgtgc agacttcgtc gatggagcgg
     3661 tcccagcttt tatcatggca gaggatcgtg gttgctaaaa tgatctgcgc cttcggataa
     3721 agctgcatca gtttttcgat gaatgcctga taatgtttnn nnnnnnnnnn nnnnnnnnnn
     3781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     3841 nnnnnnnnnn nnnnnnnnga gaaatcccac tgtttggttg gcccaagatc cgggtggtac
     3901 tcgatcttgt catagcagga ctcgacacct ttatagtgcg gtgctgcaaa ccagccggta
     3961 tcatctaaaa gtgagattcc accctgtgaa gtgtcgtgga tctgcgcatt taatttccgc
     4021 gccgtcatcc acgcatacga ataccagctg ttcgaatatt ccccatcatg ctcaggatcc
     4081 ggctttccaa catatgccac agcctccgaa acttctccac aggaaacact gtcaccaaaa
     4141 aattccattt tccgttttgg tttttccggc agtggcagaa cttccgctcc atcatcaatc
     4201 tcaaatccat agaacgtaaa agtatgacag gaatccatac gcttaaataa cagcagttca
     4261 tgtgttccct ctgaaagtcc ctccgccaaa gtataagtct ttttctcttc atcagacgac
     4321 aaggtaaaac gcttctgttc cccgtctata aaatatccca gttcattcgt ccagcaggaa
     4381 cgatggtttg cgatcactgc ctttaaggat gttccggcaa atttcattcc aattgagctg
     4441 cacgcataga caagaaccgg tgcaagcctg tcatcaaaat caattcttcc gctgtaagac
     4501 aacatttcat tatctggttt aattatcatg ttctgagttt ccctccaaaa attaaatatg
     4561 taagcagact gcccgctccg cggacattcc attatgataa aatgcacgtt ctgcggacac
     4621 tccatcacac gtttcatgaa ttacgcaaca aggctgccgc aattttcatt gcatctggca
     4681 gcctgtgtta tgaattaatt ttatgctatt aaggatgaat agcagcaatt ttagcgtctt
     4741 ccgatctcgg tatcttccgg tgttacgaca ctgttttcct tgatataatc aatgatatca
     4801 tcaagttctg tgaatgcaag accaacatag ctgtctgcag caccgtaata aattgcaatt
     4861 tttccggatt cggaatcatg gattgttgca catgggaagc atacgttcgg aacaaatccg
     4921 cgctcctcat accattcttc cggtgtgagt aagaatgtct cacaacgata ttttacgata
     4981 gatggattgt caatgtctaa gattgctcca ccgatggaat atacataacc gttacaggtt
     5041 ccgcttactc cgtggtagaa taacagccat ccttcggatg tttcgatcgg ggcagcacct
     5101 ccaccgatct ttaaggactc ccaccactca gagcctttgc ccatcacatg tctgtgtttg
     5161 ccccagtaag taagatccgg gctctcgctc acgaaaatat caccaaatgg tgtatgtccg
     5221 ctgtcggacg gacgggataa taacatgaaa tttccgttga tctttcttgg gaacagcact
     5281 gcatttctgt tgaatggaag gaacggattc tcaattcttg tgaatgtctt gaaatctgtt
     5341 gtctttgcca taccgattgc tgcgccgtag aaatcctgac accagatgat gtaataggta
     5401 tcttctactt ttacaagacg cggatcatat gcataacgcg gcataaacgg tttgccttcc
     5461 tcgtctacga aattgatctt gttttcatca aaattccagt ggatcgcatc tttgcttctt
     5521 ccaaggtaaa tgtaaggaat accgttagtc tgctctccac ggaatacacc gatgaatcca
     5581 tcttcatacg gcataacggc actgttgaaa attcttgcaa caccttttac cgggttacgt
     5641 ccgatgatcg ggttctcatt gtatctccat accggtgctc ctgttaagtt ttccggtctt
     5701 tcctgccatg gtacatttgg taccggctgg ctgatcattt tatatttgct cattttcttc
     5761 ctccatttct gcgtcttaca tccacgcacc tgcagattct atctgcaatt tattttcgtc
     5821 gttctttttt atttcttatt tatcttcctt tgcaaggaac tctaaattct tctcgatcag
     5881 tccgcatctc tgtgccacac actcaacgct tctgcccgga tcctgcggtg tattaaatac
     5941 ataatctacc agtttatcca cagtagttgt cgctacatgc attctcgtat cagaagatgc
     6001 atagtagata aatacttcgt tattctcatt tacgatcgca ccgttggtaa atacaacatt
     6061 acttacgtca ccgacacgct cttcacctct cggtccaatt aaaagtccgg acggctctgc
     6121 gatcactttt gacggatcgt ttaaatctgt tgcaaatgca tagatgacat aacgaagtcc
     6181 tgctgcggta ttgcggacac catgtgcaat gtgaatccag cctttgtctg tcttgatcgg
     6241 agttgcaccg gcaccattct ttgcctcagt gatcgtgtgg tatttacgga gacttgtcat
     6301 tttctcttca tcgatcacgg cgtgtgtaat gtcatcacaa agtccgaatc cgattccccc
     6361 gcccgatcct gtctcgataa aatcatccat cggtcttgtg tagaatgcat atttgccgtc
     6421 tacaaattcc ggatgaagta ccacgtttct ctgctgcgga gaatttaaag taacaaggtt
     6481 tggcagtctc tcccagttct ttaagtcttt ggtacggacg attccggctg ctgctactgc
     6541 tgcggaaaga tcgtttacgg ttgtgtcttt tgattcagaa cagaatacac catagatgta
     6601 accatcctca tgtttagtca gacgcatatc atagacattt gtctcttccg gacaggtatc
     6661 cggtaaaagg atcggataat cccagaaacg gaaaccatcg attccgttat cactctcagc
     6721 tacgccaaag aaagattttc tgtcgtttcc ttcgattctt gcaaccagat aatattttcc
     6781 gttcagctca atcgcaccgg aattcatcac tgcattgatg ccaaggcgct ccataaaata
     6841 tggatttgtc tccggattta agtcatatct ccaggtcagc ggaatatgct ctcttgtcag
     6901 taccggatat tcgtaacggt catatacacc attgtaaaaa tccgatttta catttttgcg
     6961 ggaaagcagt ttttcctgct tttctttttc tacataatat ctctcatgta acattcgtcg
     7021 aatctccatt ctttttctaa aaataaatga atctgtttta tgctccgatt ctgcggatga
     7081 cttctataca cattcttcca ttatgatacg gacatttcca cggctctacg atcggtctgt
     7141 ctaaaatcgg acttccatcc tcattgactt cccagaacca ctcagaacca tttctcttat
     7201 caaccacata ggttttgatg aactcccact ctgccagtgc agcatcgcga tattcagaat
     7261 gtcctgtgtt tctttcataa ccgtttaaga aaccaacaac tgtttctgcc tgcacccacc
     7321 agacgcggtg tgcattgacc actccgcggt cacattcatt tgcaagagaa tgaccatcaa
     7381 atgccacctg ataaattctt gaggtcagtg tctttgtgat cggtgtcatt ttctcacggt
     7441 aatgttcatt gtttaataca tcgacaccgc gatccatcag ccatgctgtc tcaatgtcat
     7501 gaccataaga atgaaggtct aagattgtgt tatagtctgc atcaaaaaat acttcctgac
     7561 gctgttttgc cggattgtat accttatctg caaaggtatc catgatccac atcagtctct
     7621 ttccaacctt ttcatttttt gtcacgcggt acaattctgt atacgcttca aaaacatgaa
     7681 gcagtgtatt cattgtctta tctgcaagta caccgttctc agaaagcttt tcgtttgatt
     7741 ccggtttaaa atctcttgta aaagcttcta agtagccgat ctcatcggtg cagcgctcct
     7801 caatgatatc aaacagggaa aaagcaagtt ctaacgcttc cttatccccg actgcatcat
     7861 agtaagatga caacgcataa atacagaatg cctgattgta tgtatgttta gttgtatcaa
     7921 gtggtgttcc gtcataattt aatgaccaga agatccctcc gtattctttg tcgatacaat
     7981 gttcccttaa aaattcataa ccatgttttg cctcggcaag caggtcttct cccttaaaac
     8041 ctgctgcctc gcattcctct tccgaaatgc cgccgtcttt ataaagtaaa tacgcatttg
     8101 caaaaaacca ggtaatacgg ctgtttaaga tacatccttt ttctgctttt tcatccagtg
     8161 caagatcata ggaaagataa ccgtaatatc cgccgaactt atcatcccgc atacctctcc
     8221 aaaatggaat gatatgtgtg agcagttcgt gttttgcttc tgctgcaagt tcttttaact
     8281 cactcataac cgtttcctct ttctctcttt agccttttac tgcaccagca gcaattccac
     8341 tgtaaatctg tttctgacag aggataaata cgatcaatgc cggaagcagg gaaatgataa
     8401 cacctgcaca gatcaggttg tactgacttc ccatcgggcc aacaaatgta taaagtgatg
     8461 tcgcgattgt atgtaacttt ttatccatca gataaaggtt tgccatatag tactcgttat
     8521 aaacaccaac gccctttaaa atacaggatg tcacgattgc cggttttaac agtggaagca
     8581 taattttcca gtaaattgtc cagtaggatg cgccatcaat gattgccgat tcatccagag
     8641 atattggtat attttccata aactgaatga aaatgtaaat tgagataaca tccgttccgc
     8701 acatcagaat aatatatcca tataaatgat tgacaaagtg cagtgctgtc atgatattat
     8761 atacagttac ctgcattgca actgccggaa gcagtgaagc aaacaaaaac aggtttcgga
     8821 tcagtccgtt tcccgggaat ttaaaacggt ttaatacata agcaagctgt gttccgatta
     8881 caatggaaac aaccaggaca gataccataa cgatcacgga gtttaagaaa gctcttccca
     8941 tatccgctgt ctgaaatgct ttaataaaat tatcaaaatt cagccagttc ttcggcaatg
     9001 tcataacatt ggtcgtctga tattcttcct gtgtcttaaa cgctgtaatc acacaggaga
     9061 taacaggaac aactgcacaa agtccaaaga aaatcaacga tacatattca acgatcagcc
     9121 agaggattgc accaacggta taatgttttt ttcttttctg cacatttaca ttatgttttc
     9181 tcatcttcct atgccactcc ctttccagct ttctttgcct gtttttctgc ttttaatctt
     9241 gcgcgttttg ccttgtagga ttcatcctca ctctcagcat cacggaagat atatttaaag
     9301 aataacttct gtaaaatcgt acatgcaaaa atgataagga gaagtacgac tgccattgct
     9361 gatgcaagac cgactttctg gcttacatga gcgatctcat tcataattac aaaatatgtt
     9421 ccggttccat ttgcaccatc tgtgataacg taaggctgct caaatgcact taaggaacct
     9481 gtgatagaaa gaattacatt taaagtgata attgttttga tactcggcag aataatatgt
     9541 ttaaactgct gaaatttatt tgcaccatct aactctgctg cttcgtaaag gtctgcatcc
     9601 acagacatga ttgcaccgat aaacaatacc atgttctgtc caaaataacg ccataccgaa
     9661 gtagccacca aagaccagtt gttaattgac tgatctttca gccagtatgg aagattgtca
     9721 agtttaaatc cacaccattg taagatcgta tcaaatacaa atcctctggt atagaaaaat
     9781 ttaaaaataa atccgatcgc aataccactg atcagatatg ggaaaaacat taacccttta
     9841 aagaagtttc ctccctttac tttaaaactt aaaatagttg ccagataaag tgcaagcaca
     9901 agctgaatga ttgcacctac catataataa agactgagct ttaatgctcc aaagcagtca
     9961 tccctgcgaa atacgtcaat ataatttttg aatccgacaa attttctctg atctaccgga
    10021 gttaaatatt tcatcttata aaaactaaat tttaccatct cggcaaaagg cagataagta
    10081 aatacaaaca gcaacagcag cggaattgtc ataaatgcca cgcagataat cacctgctgt
    10141 ccttttctgc tttttgccca ttttgtaaaa ctgaatggtt ttttcccttc catatccaca
    10201 attcctccat ccattgtctt ttatccggga aggggaacct ccccttccct tttgtggaac
    10261 tatattactc agttacttca attccgtttg attcctgtgc atcagaccat gctgtgttcc
    10321 attcgtccat gatctcatca aatgtcttat cgccattgga tgcatgctca atgattgcct
    10381 ggattttact gtctccacct gcgttaatat ttaactcaga ctctgcattc atctcattta
    10441 agaaatcttc ctcgccagct aatgcaggtt catcctctaa gaatgttacg ccatcgaagg
    10501 aaagttttgt atctgtactg ccggctgcga ctggaagtcc atcctcgttg tatgagaaac
    10561 cggatttttc tgtcatccat tttacaaata ccatagctgc tgctttttca tcatctgttg
    10621 catttgcatt gataccataa gagtaatcag cacctgcgga tgcatactgc tcaccattta
    10681 cagtgatcgg gaatggcata taaccgatat ctgcgccatt ttcgcctgct gcttccatct
    10741 gaggataagc ccatgagcca agtaccatac aaccgatctc accattgttg atcatacctt
    10801 tacagccctc ccagtcagtt gttgcaaagt catcttcgat cagtccgtct gcaactgcat
    10861 catagaggat cttgtaaact gcataagcat gtgtatcatc gccataattc tggaatggat
    10921 cttttgtatg aactaatttc tggttcatat atgtattgtc gcctgttgca ttatttccga
    10981 tgtaagcatc ccatgctccc attgtccagc ctgctgcata gtttgtataa agtgggatgg
    11041 catctgtatt atctttgatt ttctgtaatg caccgataaa ttcttccgga gtctttggaa
    11101 gttctgtaac tcctgcttct tcaaatactt ttttattgta tacgataccc tgtgtagttg
    11161 ctgtagaagg aacaccgtaa acctgtccgc catactccca tgtagttgca taattgatct
    11221 gggtcttcat ggtatcaaga tcaccatatg aaataaagta attgcttaag tctgccttat
    11281 caaccgccgg gatcatcatg actgtctcat agtcaccgga ctgtaaatgc atcagagcat
    11341 catctgcata gttggtatcg gttgtaagtt caactgtaat atttggatac atttcattga
    11401 atgctgctaa atactctttc catgttgttc cgttataatc gtcagattca agatctgttc
    11461 tgtggttgaa taatgaaatt gttgctgtca gatctgtata atcctcacca agtttgatat
    11521 ctgcatagga taaagatccg tctgcggatg tagaagcatc accactctca gttgctgcta
    11581 catcatttga tgcatctgtg ctgttatctg ctgctgcact gttgttgtct gttgttcccc
    11641 cattgcctgc tgtgttgttt gagccaccgc atgctgccat gctcatggtc attgctgcta
    11701 ctaaagtaac ggctaaaact tttcttaatt tcatagaatt ttcctcctta tgatgtttgt
    11761 tacttgtttt gtaacttaat ttaattatat atcgttttat tttttagtca acactttttt
    11821 cctgatttta gcccatttta acccttctat tgtgcatttc ggcactatag acaattcttt
    11881 tttgctgttt ttgtgcactt tttcacattt atttttgttt taattttgtt ttttagctta
    11941 ttttagtcta tattttgtaa attgattaat tcacttattt accttgattt tagtttaact
    12001 aattacttat ttcgccacag cgttatctgc agaacatcca taacttaaca atatgaaatg
    12061 ctcaccaaat gatggtttgt gggtgacatg agtttccttg tgtagggtgg ttctgggggg
    12121 ttacgattgg caaattgcat caagccggga ctgttttgtt tccgttgtcc gaaaataaga
    12181 aactctaagc atgcctgatt caggttgggg cggagtgacg tgtacgtcct aaatgcgcca
    12241 tccgggcaca ttaggacttg tgctgccgtc catggcagca caacactatg ttgcgaacag
    12301 gcatcctaag agtttctaat ttccttccaa agtcacaaaa cgagtctcgg cttgatgcga
    12361 tttgccagcc gcaaggttgt gaaccactct tcgtcgggga actcatttta caaccttggg
    12421 ggtgcgtaaa tttttgtgac attcatttca aaaaggttga aaaatctcga cacaatctgt
    12481 tatatctatg cttttaaaca tacatacttg gaataataat ctgcattatc agtctggtaa
    12541 tttacgaaat gattaatgta atgcaacata gcagatgaaa cttcagacaa gtcatcaggc
    12601 tgaatattaa tgatacagca cattacgatt ttaagcatat ttccattcgt gcgaatatca
    12661 aaaattcaca cccgcacccc caattctgag atgaaccgcc cgcccaaatg gtgttcataa
    12721 cctgaaggct ggcatcttgc gcaaagccag agctaatttt gtgactttgg aagaaaatta
    12781 gaaaatcttg gtgtgcctgt ctacacatag tgatgttctg ccacggatgg cagaacaagg
    12841 cagcatcgag tcatggatga ctcgttgttg ccggtcacgt cactccgaga aaatctaaac
    12901 caggcatacc tagacttttc ttattttcgt acaacggaac caaaattaac tccggctttg
    12961 cgcaaaatgc cattcacaga cctacgacac accatttgga cgggcgaagc atgtcaacca
    13021 caagccaaaa tttggtgtga aatccatgaa acgaaaaaaa cagaaagcgg caagcctttc
    13081 acaacttacc gctttctctt attttacaac ctgctgcacg ctggcttttt ccaccagtct
    13141 tccctcaaca atggtaatcc cttgtttgta gcgttcaccg ccgacttttt tcagcaacac
    13201 atgaatcgct ttatttgcca tttcacgaat atccacctca taggttgtga tctcaacatc
    13261 acataagccc gggaaaagat agttgtcaaa tccaaccacc gaaaaatctt gtggaacacg
    13321 atatccctgt tcttctaact gattgatgac catgcttgcc gtgagatcgg agttgcacac
    13381 aaatgccgtc ggcatatctt tcatctgatc cggatgaata tcaaccttta ccacaccaca
    13441 ttccatatca cgatccgata tgatccactc ctgtggcact tcaataccat gttctaacat
    13501 ggatttccgg taaccgaaat aacggtctgt aatacttgcc gtaaacaaca gtgttccgac
    13561 atacgcaatt ttttcatgac catgctcgat cagataattc gtcagcatgt aagtgccata
    13621 gtaactgtta gagatcaccg catcactcat ctgatgttca tcgtaaaaat caagatatac
    13681 gatcgggatc tgcgtattct gtcttaatgc acctaaatat tctgtcttca gccgtccgat
    13741 cagaatcaga ccatctacct tccgctccag cacgatcttc ggcagattag cctctgcttc
    13801 atcttctaac gataccactt caagcatcgt aaagcactct ttctgcaccg ctctcgttgc
    13861 aacgctctga tacattctcc agtaaaagga tgcatactct cccagatatt tttctgatac
    13921 taaaactccg atattataac tttttgctga cttttctttt tttacggcag atggctgctt
    13981 gtatccaagt tcatctgcca attgtttgat tttttcccgc atagcctcgc tgacaccttt
    14041 ttgtccggaa agtgcttttg agaccgtgac cgtactgaca ccaagctgct ctgcaatgtc
    14101 tgccagcttt actgcttttg ccataaccgt ccccttctta ctacttttta ctttttcgat
    14161 ttaatcttat ttcttttcca caaaatgtaa cagttttgac tggaaatcac cccatggatt
    14221 ctggatcaga atacctgcat acattaatgt atctcccgca tatacagtat cttcgccttc
    14281 cagacagtaa ttcttctgcg gatcgagtcc ttttaatgtg attcttctgc tcttataatt
    14341 cggacggttg atcacctgca caaatgtaac cagtgcttct gatttatctt ttgaaaccac
    14401 ctcgtaacag tcaaaataat gattttcctg ataggaggcg atcctgtaat aatcgccgct
    14461 tcttaccaga tcattgtatt tatgatacat ggcaacctgt ttcgggatca tctgtctgtc
    14521 ttcttccgga atctttgtga tatccagctc ataaccgaaa gttcctgcaa gcgctacatg
    14581 acctcttgtc tcaaacggtg taacacgtcc caccgtatga ttcggacagt ctgaaacgtg
    14641 cgctcccatc gtcgataacg gatagatcat cgccgtactt tcctgaatct ttaaccgctc
    14701 caccgcatcc gtatcatccg agcaccagat ctgtggactg taataaagca tacccggatc
    14761 aaaacgtgcc ccaccgccgg aacagttttc cagtaaaaga tgtgggaact ctgttaccag
    14821 acgctcctgc atctcataca ctgccagcac ataacggtga taaagttcac cctgtcggtc
    14881 tgcaggaagt ccaaagcttc cgatgtcaga aagctgacgg ttcatatccc atttgacata
    14941 ctcaatattt gcactgcgta agatcgacgc cacgctctca tatgcataat cgcgcacttc
    15001 ttttctggta agatcaagta catactgatt tctgcagaga gatccctctc ttcccggaat
    15061 ctgaattgcc cagtccggat gtgcctcata aagttttgaa tccggtgaga tcatttccgg
    15121 ctcaaaccag ataccgaatt ttaatccaag cttatttacc tcatctacta gatgttttaa
    15181 accaccgttt aatttttctt cgttgacata ccagtcaccc agacttgatg aatcatcatt
    15241 gcggtgtcca aaccagccat catccataac cagcatttca atgccaagtt ccgatgcttt
    15301 ttttgcaatg gaaagtaatt tttctgtatt gaaatcaaaa taagttgctt cccagttgtt
    15361 gatcagaatc ggacgtttct tatccttata ttcgctgcgg atcaggtggt tccggtaaag
    15421 ttcatggaac tggtgtgtca tgccgtcata tccggtgtca ctgtaaacca gcacaacttc
    15481 cggtgtctgg aaactctcac ctttttctaa cttccagcag aagttctccg ggtgaattcc
    15541 catgcctacg cggacagtat caaactgtcc cagttccacc tgtccgataa agttgccgga
    15601 gtatacaaaa tgcataccat atacttcgcc ctgtgactgg tcagcgtttc ctgccgcaag
    15661 tgccatgaat gggtgttcct gatgggaaga ctcgcctctt acagattcca cacccataaa
    15721 tccttttttc actttgcggt gttctaacat acgctctctc gcccaggaac catgcatcgt
    15781 aagaagtgta aaatcacggt tatccatatc catggagcaa gacagtgctt tcgtcagata
    15841 caacatctcg ccgttatttt cgatccgcac gcttcttgtg atgacatcca catccgaaaa
    15901 tgccgtatag agcaatgtta ctttcaatcc aagtaccgga tcctcacaga gaagctctaa
    15961 tgtctcgcag gcattctcgt ccccaaatgt tgcagggaga ccggcaagtc ccggttttcc
    16021 tgcataaatt ttatgtgaaa cataaaacag tgacactgcg gtgtgtccgc ctgccgttct
    16081 taccgagata ctgcttcttc tgtaatctcc gagtccgttt ccggcatatt ccatcggaaa
    16141 tgtatcgtaa aaagaaacac gctccctgtt attttccgaa ggcacaaacg gtccttctcc
    16201 tgtacggagc aggtacgcga tgtttgcatc tcttaatttc ttaccataat aaacatgacc
    16261 gacaaagttt tctttatcca cgataccgat cacataactg gaggctggtg tatccagctt
    16321 gaaaatgcgt tctttttcaa agtatgtgat tgccatgctg tatttcctcc tgttatttca
    16381 gcaagtcttc ttttaacacg gcaagtttct tttctgcatc ctctaatgaa ctgcctttta
    16441 cgccaaagta atatttgatc ttcggctctg ttccggacgg acgcatacag caccatgcgt
    16501 tatcagaaag ttcatagtaa agtacgttgg attccggcag acctgtcttt gtcacttctc
    16561 cggtcacagt atcttttctg gtatcttctt tatagtcgcg cactgcaagc acatcaaatc
    16621 cgccaagtgt tttcggagga ttttttctgg aattgctcat cagttcctgg atctgtgcag
    16681 ctccgtcgat tccctttaat gtctttgtct caagtccctc tctgtaatag ccgtatttct
    16741 catacatggc aagcatctca tcccataagg tcatattgtt cttcttgcac caggaagcaa
    16801 cctcacataa catcatgact gcaacacagg catccttatc ccttgcgtaa gtacctgcaa
    16861 ggcatccgta gctttcctct aaaccaaaca cataatcgta agtattctgc tgctcgaaaa
    16921 atttgatctg ctctccgata tatttaaatc cagttaaaac ttcgatcagt tttacaccgt
    16981 aagcttttgc gatcgctttt gccatatcgg ttgtaacgat tgtctcaacc agtgcaggat
    17041 tcttcggcat agttcccatt gctgtttttt ctcttaaaat gtattccgcg atcagcatac
    17101 ctgacatatt tccggtaaat gtcacatact cgccactctt cgtatctttg cagtatacgc
    17161 caagacggtc tgcatccggg tcagttgcaa gaacgatgtc cgcatccact tcttttgcaa
    17221 gttttaatgc aagttcaaat gcttttggtg actccgggtt cgggtatgca acggtcggga
    17281 aattaccatc cggtttttcc tgctccggca ctacatatac atgctcaaaa ccaagctctt
    17341 ttaacacgcg gcgcaccgga agatttccag ttccgtgaag cggtgtgtat acgatcttga
    17401 tatcttttgc catctctttg atgatctcag gatgaatgga ctgttttttc agttcttcca
    17461 tgtaacggtc atcaatctct ttaccaatca cattgtaaag gcctgctgca actgcctctt
    17521 cttttgccat ggtctttacc tgatcgaagg aagttacttt tgcaacttcc gctaaaatat
    17581 ttttgtcgtg aggcggtgtg atctgtgcac catcttccca gtatactttg tatccgttgt
    17641 attctctcgg gttatggctt gctgtaatta caataccgga aatacatcct aactcgcgga
    17701 ctgcaaaaga taactccggt gtcggacgaa ggctgtcaaa tacatatgcc ttaatgccgt
    17761 ttgcatttaa gcagagtgct gcctcctcgg taaattccgg ggacataatt ctggagtcat
    17821 gtgcgatcgc aacacccttt tcctgtccat tctgggaaat aatgtaattt gcaagtccct
    17881 gtgttgcctg acgtacggta taaatattca tacggttggt tccggctccg atcacgcctc
    17941 ttaaaccacc ggtaccaaat tctaactgtc tgtaaaaacg atcctcgatc tctgcctgat
    18001 ccccctcaat cttctttaac tcagcctttg tatctgcatc aaaatatgga tctgtgcacc
    18061 actgtttgta tgtttccatg taattgctca ttcttcttct cctttacttt tctgcgattc
    18121 attttttatt atattttgga ttataacctt tttttaagtt attgtaaact aattttaacc
    18181 ttttgactat ttttatttaa aaatcagctt ttgacctcaa catcatttat taaaaatatc
    18241 ataatatttt tttacgactt tttctgcggg ctttgcataa atttcatagt ccatacgggt
    18301 ctttgcgctc cgctcctgat aaagctttgc atcccaggac cagagcgcca tacctcctac
    18361 ccagtctctt ttactgcacg ccgtaaacat atcttcgtac cattctgcct gaccctttgg
    18421 atccgcatca cctcttacac accagtcatt tggcacctct ttggaacctt ttaccgacat
    18481 acatcctgtt tccgcaaaga aaaacggttt ttgaaatctg tttaccacgg tttcaatacg
    18541 atccagctga ttttcccagt ccccatatgg atagtaacca ctcgaagaaa tcacatccac
    18601 agcatcccac cagtttaccc ggtgttcctg atacttatct gtattatagg aaagcagtcc
    18661 atgatagacc tgtctgatat ccgagagcag tttgcgccat tctgcttcac ggtgctcact
    18721 catcaccatc tcgcagccgg caataaacat ttcacagtca tgctgttctg caattttcgc
    18781 atagtgaagc tgaaatgccg tataggatgc aaaccagttt ccccatttcg gttcacacgg
    18841 aacatcctca tcaaaaaaat taatatgcgc ccgccaggtc ccgtttttac agtttacggt
    18901 cggttttaat gccacacgaa gccctatttc ctttgcatat tcaatcatag cgatcagctc
    18961 gtcatcttcc atcgtcgcct ttgatgtgaa gcagatctcc tccgactgcg gtgtctcctg
    19021 taaccctcca ggcacaaata tcacgaaatt tgcgccggtt ctctccttca tcatagcaag
    19081 gctctccttt gcccccggtt taaaaaaagc cccggcacac gcaaacggtg caaaagtcac
    19141 cccacagata tattccat
//
