Substrate_high_level Substrate_curated Family Name EC_Number acetylmannan acetylmannan CE17 acetylmannan esterase 3.1.1.- acetylmannan acetylmannan CE2 Acetylmannan esterase 3.1.1.- acholetin acholetin GH94 acholetin phosphorylase 2.4.1.- agarose agarose CBM101 agarose binding property of a module associated with a GH86 in Wenyingzhuangia fucanilytica agarose agarobiose GH117 agarobiose exo-a-1,3-anhydro-L-galactosidase 3.2.1.- agarose neoagarose (marine algae) GH117 beta-D-galactofuranosidase 3.2.1.146 agarose neoagarose (marine algae) GH117 alpha-neoagaro-oligosaccharide hydrolase 3.2.1.159 agarose agarose (marine algae) GH118 beta-agarase 3.2.1.81 agarose agarose GH16 beta-agarase 3.2.1.81 agarose porphyran, agarose GH50 beta-agarase 3.2.1.81 agarose porphyran GH86 beta-porphyranase 3.2.1.178 agarose porphyran, agarose GH86 beta-agarase 3.2.1.81 agarose agarose GH96 agarose endo-a-1,3-anhydro-L-galactosidase 3.2.1.158 alginate alginate CBM106 alginate binding alginate alginate CBM96 Modules found with a large diversity of GH and PL families alginate alginate PL14 alginate lyase (unspecified) 4.2.2.- alginate alginate PL14 exo-oligoalginate lyase 4.2.2.26 alginate alginate PL14 poly(beta-mannuronate) lyase / M-specific alginate lyase 4.2.2.3 alginate alginate PL15 oligoalginate lyase / exo-alginate lyase 4.2.2.26 alginate alginate PL15 alginate lyase 4.2.2.3 alginate alginate PL17 endo-polyMG-alginate lyase 4.2.2.- alginate alginate PL17 alginate lyase (unspecified) 4.2.2.- alginate alginate PL17 exo-b-D-mannuronate-alginate lyase 4.2.2.- alginate alginate PL17 guluronate-specific alginate lyase 4.2.2.11 alginate alginate PL17 exo-polyMG-alginate lyase 4.2.2.26 alginate alginate PL17 endo-b-D-mannuronate-alginate lyase 4.2.2.3 alginate alginate PL18 endo-polyMG-alginate lyase 4.2.2.- alginate alginate PL18 endo-polyGM-alginate lyase 4.2.2.- alginate alginate PL18 alginate lyase (unspecified) 4.2.2.- alginate alginate PL18 poly(alpha-L-guluronate) lyase / G-specific alginate lyase 4.2.2.11 alginate alginate PL18 alginate lyase 4.2.2.3 alginate alginate PL31 poly(beta-mannuronate) lyase / M-specific alginate lyase 4.2.2.3 alginate alginate PL32 poly(beta-mannuronate) lyase / M-specific alginate lyase 4.2.2.3 alginate alginate PL34 alginate lyase (unspecified) 4.2.2.- alginate alginate PL36 poly(beta-mannuronate) lyase / M-specific alginate lyase 4.2.2.3 alginate alginate PL38 exo-b-1,4-glucuronan lyase 4.2.2.- alginate alginate PL38 endo-polyMG-alginate lyase 4.2.2.- alginate alginate PL38 endo-polyGM-alginate lyase 4.2.2.- alginate alginate PL38 guluronate-specific alginate lyase 4.2.2.11 alginate alginate PL38 endo-b-D-mannuronate-alginate lyase 4.2.2.3 alginate alginate PL39 endo-polyMG-alginate lyase 4.2.2.- alginate alginate PL39 endo-polyGM-alginate lyase 4.2.2.- alginate alginate PL39 guluronate-specific alginate lyase 4.2.2.11 alginate alginate PL39 endo-b-D-mannuronate-alginate lyase 4.2.2.3 alginate alginate PL41 endo-b-D-mannuronate-alginate lyase 4.2.2.3 alginate PL44 endo-b-D-mannuronate-alginate lyase 4.2.2.3 alginate alginate PL5 alginate lyase 4.2.2.3 alginate alginate PL6 endo-polyMG-alginate lyase 4.2.2.- alginate alginate PL6 endo-polyGM-alginate lyase 4.2.2.- alginate alginate PL6 alginate lyase (unspecified) 4.2.2.- alginate alginate PL6 exo-a-L-guluronate-alginate lyase 4.2.2.- alginate alginate PL6 poly(alpha-L-guluronate) lyase / G-specific alginate lyase 4.2.2.11 alginate alginate PL6 oligoalginate lyase / exo-alginate lyase 4.2.2.26 alginate alginate PL6 alginate lyase 4.2.2.3 alginate alginate PL7 poly-(MG)-lyase / MG-specific alginate lyase 4.2.2.- alginate alginate PL7 endo-polyGM-alginate lyase 4.2.2.- alginate alginate PL7 alginate lyase (unspecified) 4.2.2.- alginate alginate PL7 alpha-L-guluronate lyase / G-specific alginate lyase 4.2.2.11 alginate alginate PL7 oligoalginate lyase / exo-alginate lyase 4.2.2.26 alginate alginate PL7 poly(beta-mannuronate) lyase / M-specific alginate lyase 4.2.2.3 alginate alginate PL8 poly(beta-mannuronate) lyase / M-specific alginate lyase 4.2.2.3 alpha-galactan alpha-galactoside, galactose oligosaccharides (plant), galactomannans (plant) and galactolipid (animal) GH27 alpha-galactosidase 3.2.1.22 alpha-galactan GH31 exo-a-1,4-galactosidase 3.2.1.- alpha-galactan alpha-galactoside GH31 alpha-galactosidase 3.2.1.22 alpha-galactan GH36 raffinose exo-a-1,6-galactosidase 3.2.1.- alpha-galactan GH36 melibiose a-1,6-galactosidase 3.2.1.- alpha-galactan alpha-galactoside (galactose oligosaccharides, galactomannans and galactolipid) GH36 alpha-galactosidase 3.2.1.22 alpha-galactan alpha-galactoside, melibiose and raffinose GH57 alpha-galactosidase 3.2.1.22 alpha-galactan plant pectic polysaccharide, xylan GH95 alpha-L-galactosidase 3.2.1.- alpha-glucan starch AA13 lytic starch monooxygenase / starch oxidase (glycosidic bond-cleaving) 1.14.99.55 alpha-glucan starch, cyclodextrin CBM20 The granular starch-binding function has been demonstrated in several cases. Interact strongly with cyclodextrins. Often designated as starch-binding domains (SBD). alpha-glucan granular starch CBM21 Modules of approx. 100 residues. The granular starch-binding function has been demonstrated in one case. Sometimes designated as starch-binding domains (SBD). alpha-glucan starch CBM25 Starch-binding function demonstrated in one case. alpha-glucan starch CBM26 Starch-binding function demonstrated in two cases. alpha-glucan granular starch CBM34 Modules of approx. 120 residues. Granular starch-binding function has been demonstrated in the case of Thermoactinomyces vulgaris R-47 alpha-amylase 1 (TVAI). alpha-glucan starch CBM45 Modules of approx. 100 residues, found at the N-terminus of plastidial alpha-amylases and of alpha-glucan, water dikinases. Starch-binding activity demonstrated in the case of potato alpha-glucan, water dikinase. alpha-glucan glycogen CBM48 Modules of approx. 100 residues with glycogen-binding function, appended to GH13 modules. Also found in the beta subunit (glycogen-binding) of AMP-activated protein kinases (AMPK) alpha-glucan starch CBM53 Starch-binding function demonstrated by Valdez et al. (2008) [PMID: 18260645] alpha-glucan maltoheptaose CBM58 The CBM58 module of the Bacteroides thetaiotaomicron SusG protein has been shown to bind maltoheptaose alpha-glucan maltotriose and maltotetraose CBM68 Binding to maltotriose and maltotetraose shown for the pullulanase of Anoxybacillus sp. LM18-11. Binding function derived from crystal structure and deletion of the CBM, which showed reduced specific activity and increased Km value compared to the wild type enzyme. alpha-glucan starch CBM69 starch-binding function demonstrated in one case, distantly related to families CBM20 and CBM48 alpha-glucan starch CBM74 Modules of approx. 300 residues appended to several alpha-amylases. The starch-binding function has been demonstrated for the CBM74 appended to the GH13 alpha-amylase of Microbacterium aureum B8.A alpha-glucan starch CBM82 The boundaries, structure and starch-binding function of the CBM82 module of Eubacterium rectale Amy13K have been reported by Cockburn and coworkers in Molec. Microbiol. (2017) (PMID=29139580) alpha-glucan starch CBM83 The boundaries, structure and starch-binding function of the CBM83 module of Eubacterium rectale Amy13K have been reported by Cockburn and coworkers in Molec. Microbiol. (2017) (PMID=29139580) alpha-glucan amylopectin CBM98 amylopectin binding activity in the multimodular SusG protein of Bacteroides ovatus alpha-glucan starch GH119 alpha-amylase 3.2.1.1 alpha-glucan starch GH122 alpha-glucosidase 3.2.1.20 alpha-glucan starch, glycogen, and malto-oligosaccharides GH126 alpha-amylase 3.2.1.1 alpha-glucan GH13 a-glucoside phosphorylase 2.4.1.- alpha-glucan GH13 a-glucosyltransferase 2.4.1.- alpha-glucan GH13 a-1,6-maltooligosyltransferase 2.4.1.- alpha-glucan GH13 acarviosyltransferase 2.4.1.- alpha-glucan GH13 a-maltosyltransferase 2.4.1.- alpha-glucan GH13 sucrose a-transglucosidase 2.4.1.- alpha-glucan starch, glycogen, and malto-oligosaccharides GH13 oligosaccharide alpha-4-glucosyltransferase 2.4.1.161 alpha-glucan starch, glycogen, and malto-oligosaccharides GH13 branching enzyme 2.4.1.18 alpha-glucan cyclodextrin (alpha-1,4 glycosidic glucan from starch degradation) GH13 cyclomaltodextrin glucanotransferase 2.4.1.19 alpha-glucan glycogen GH13 4-alpha-glucanotransferase 2.4.1.25 alpha-glucan starch, glycogen, and malto-oligosaccharides GH13 alpha-1,4-glucan: phosphate alpha-maltosyltransferase 2.4.99.16 alpha-glucan GH13 palatin a-1,6-glucosidase 3.2.1.- alpha-glucan starch GH13 maltopentaose-forming alpha-amylase 3.2.1.- alpha-glucan GH13 amylose exo-1,4-glucopentaosidase 3.2.1.- alpha-glucan GH13 cyclic maltosyl-maltose a-1,6-glucosidase 3.2.1.- alpha-glucan starch, glycogen, and malto-oligosaccharides GH13 alpha-amylase 3.2.1.1 alpha-glucan amylopectin (starch) GH13 oligo-alpha-glucosidase 3.2.1.10 alpha-glucan starch GH13 maltotriose-forming alpha-amylase 3.2.1.116 alpha-glucan starch GH13 maltogenic amylase 3.2.1.133 alpha-glucan pullulan (starch degradation by fungi) GH13 neopullulanase 3.2.1.135 alpha-glucan starch GH13 malto-oligosyltrehalose trehalohydrolase 3.2.1.141 alpha-glucan starch GH13 alpha-glucosidase 3.2.1.20 alpha-glucan starch, glycogen, and malto-oligosaccharides GH13 amylose exo-a-1,4-glucosidase 3.2.1.3 alpha-glucan maltooligosaccharides GH13 amylo-alpha-1,6-glucosidase 3.2.1.33 alpha-glucan pullulan (starch degradation by fungi) GH13 pullulanase 3.2.1.41 alpha-glucan cyclomaltodextrins GH13 cyclomaltodextrinase 3.2.1.54 alpha-glucan starch GH13 maltotetraose-forming alpha-amylase 3.2.1.60 alpha-glucan starch, glycogen, and malto-oligosaccharides GH13 isoamylase 3.2.1.68 alpha-glucan starch, glycogen, and alpha-1,6 glucan GH13 glucodextranase 3.2.1.70 alpha-glucan starch, glycogen, and malto-oligosaccharides GH13 maltohexaose-forming alpha-amylase 3.2.1.98 alpha-glucan starch GH13 malto-oligosyltrehalose synthase 5.4.99.15 alpha-glucan maltose GH13 trehalose synthase 5.4.99.16 alpha-glucan glycogen GH133 amylo-alpha-1,6-glucosidase 3.2.1.33 alpha-glucan starch, glycogen and related polysaccharides and oligosaccharides GH14 beta-amylase 3.2.1.2 alpha-glucan GH15 isomaltose a-1,6-glucosidase 3.2.1.205 alpha-glucan starch GH15 glucoamylase 3.2.1.3 alpha-glucan starch GH15 glucodextranase 3.2.1.70 alpha-glucan maltodextrin GH176 isoamylase 3.2.1.68 alpha-glucan dextran and isomalto-oligosaccharides (bacteria) GH27 isomalto-dextranase 3.2.1.94 alpha-glucan glycogen and starch GH31 oligosaccharide alpha-1,4-glucosyltransferase 2.4.1.161 alpha-glucan GH31 1,4-a-glucan 6-a-glucosyltransferase 2.4.1.24 alpha-glucan GH31 isomaltosyltransferase 2.4.1.387 alpha-glucan GH31 oligo exo-a-1,6-glucosidase 3.2.1.10 alpha-glucan GH31 dextran endo-a-1,6-glucosidase 3.2.1.11 alpha-glucan starch GH31 alpha-glucosidase 3.2.1.20 alpha-glucan GH31 cyclobis-(1,6)-a-nigerose a-1,3-glucosidase 3.2.1.204 alpha-glucan glycogen and starch GH31 alpha-1,3-glucosidase 3.2.1.84 alpha-glucan glycogen and starch GH31 alpha-glucan lyase 4.2.2.13 alpha-glucan maltose and other small maltooligosaccharides GH4 alpha-glucosidase 3.2.1.20 alpha-glucan GH49 panose a-1,4-glucosidase 3.2.1.- alpha-glucan dextran (branched alpha-glucan) GH49 dextranase 3.2.1.11 alpha-glucan pullulan (starch degradation by fungi) GH49 isopullulanase 3.2.1.57 alpha-glucan dextran (branched alpha-glucan) GH49 dextran 1,6-alpha-isomaltotriosidase 3.2.1.95 alpha-glucan starch, glycogen, and malto-oligosaccharides GH57 4-alpha-glucanotransferase 2.4.1.25 alpha-glucan starch, glycogen and related polysaccharides and oligosaccharides(containing three or more (1->4)-alpha-linked D-glucose units) GH57 alpha-amylase 3.2.1.1 alpha-glucan GH57 amylose exo-a-1,4-glucobiosidase 3.2.1.133 alpha-glucan pullulan, maltodextrins and cyclodextrin GH57 amylopullulanase 3.2.1.41 alpha-glucan pullulan, maltodextrins and cyclodextrin GH57 cyclomaltodextrinase 3.2.1.54 alpha-glucan nigerose, trehalose, kojibiose, and maltooligosaccharide GH63 alpha-glucosidase 3.2.1.20 alpha-glucan nigerose, trehalose, kojibiose, and maltooligosaccharide GH63 alpha-1,3-glucosidase 3.2.1.84 alpha-glucan kojibiose and alpha-1,2-oligoglucan GH65 a-glucan phosphorylase 2.4.1.- alpha-glucan trehalose, kojibiose GH65 trehalose-6-phosphate phosphorylase 2.4.1.216 alpha-glucan kojibiose GH65 kojibiose phosphorylase 2.4.1.230 alpha-glucan nigerose GH65 nigerose phosphorylase 2.4.1.279 alpha-glucan kojibiose GH65 a-glucosyl-glycerol phosphorylase 2.4.1.332 alpha-glucan 1,3-alpha-oligoglucan GH65 1,3-alpha-oligoglucan phosphorylase 2.4.1.334 alpha-glucan trehalose GH65 trehalose phosphorylase 2.4.1.64 alpha-glucan maltose (alpha-1,4) GH65 maltose phosphorylase 2.4.1.8 alpha-glucan Glc-alpha-1,2-Gal of collagen (animal) GH65 alpha-glucosyl-1,2-beta-galactosyl-L-hydroxylysine alpha-glucosidase 3.2.1.107 alpha-glucan GH65 branched-dextran exo-1,2-a-glucosidase 3.2.1.115 alpha-glucan GH65 kojibiose a-1,2-glucosidase 3.2.1.216 alpha-glucan trehalose GH65 alpha,alpha-trehalase 3.2.1.28 alpha-glucan dextran (alpha-1,6) GH66 cycloisomaltooligosaccharide glucanotransferase 2.4.1.248 alpha-glucan dextran GH66 dextranase 3.2.1.11 alpha-glucan GH70 reuteransucrase a-1,6-glucosyltransferase 2.4.1.- alpha-glucan reuteran GH70 reuteransucrase a-1,4-glucosyltransferase 2.4.1.- alpha-glucan starch,maltose, beta-glucan ,lichenan,laminarin, xylan GH70 alpha-4,6-glucanotransferase 2.4.1.- alpha-glucan dextran GH70 alpha-1,2-branched dextransucrase 2.4.1.- alpha-glucan glucan GH70 alpha-4,3-glucanotransferase 2.4.1.- alpha-glucan sucrose GH70 Alternansucrase a-1,6-glucosyltransferase/Alternansucrase a-1,3-glucosyltransferase 2.4.1.140 alpha-glucan sucrose GH70 dextransucrase 2.4.1.5 alpha-glucan alpha-1,3-glucan GH71 alpha-1,3-glucanase 3.2.1.59 alpha-glucan alpha-glucose GH76 alpha-glucosidase 3.2.1.20 alpha-glucan amylomaltase GH77 amylomaltase or 4-alpha-glucanotransferase 2.4.1.25 alpha-glucan alpha-1,3-glucan GH87 alpha-1,3-glucanase 3.2.1.59 alpha-glucan nigeran (alpha-glucan in fungi) GH87 mycodextranase 3.2.1.61 alpha-glucan alpha-glucose residue GH97 alpha-glucosidase 3.2.1.20 alpha-glucan alpha-galactoside, alpha-fucoside GH97 alpha-galactosidase 3.2.1.22 alpha-glucan starch GH97 glucoamylase 3.2.1.3 alpha-glucan GH97 dextran exo-a-1,6-glucosidase 3.2.1.70 alpha-mannan alpha-mannan, plant N-glycan GH125 exo-alpha-1,6-mannosidase 3.2.1.163 alpha-mannan 3-O-methylmannose polysaccharide GH178 mannan endo-alpha-1,4-mannosidase 3.2.1.- alpha-mannan galactomannan (fungi) GH2 beta-D-galactofuranosidase 3.2.1.146 alpha-mannan alpha-mannoside GH31 alpha-mannosidase 3.2.1.24 alpha-mannan mannosyl-oligosaccharide GH38 mannosyl-oligosaccharide alpha-1,3-mannosidase 3.2.1.- alpha-mannan yeast alpha-mannan (yeast cell wall) GH76 alpha-1,6-mannanase 3.2.1.101 alpha-rhamnoside alpha-L-rhamnosidase in polyphenol (naringin, rutin, hesperidin), ulvan, pectin, arabinogalactan-protein GH78 alpha-L-rhamnosidase 3.2.1.40 arabinan GH1 arabinan exo-a-1,5-L-arabinofuranosidase 3.2.1.- arabinan GH116 beta-D-arabinofuranosidase 3.2.1.- arabinan hydroxyproline-rich glyoproteins (arabinan in extensin and lectin) GH121 beta-L-arabinobiosidase 3.2.1.187 arabinan arabinan GH146 beta-L-arabinofuranosidase 3.2.1.185 arabinan arabinan GH172 alpha-D-Arabinofuranosidase 3.2.1.- arabinan GH172 exo-a-1,5-D-arabinofuranosidase 3.2.1.- arabinan GH2 b-N-acetylhexosaminidase 3.2.1.52 arabinan arabinan GH2 alpha-L-arabinofuranosidase 3.2.1.55 arabinan arabinan, arabinoxylan GH3 alpha-L-arabinofuranosidase 3.2.1.55 arabinan GH36 b-L-arabinopyranosidase 3.2.1.88 arabinan paeonolide, ginsenoside, arabinoxylan, and arabinan GH42 alpha-L-arabinopyranosidase 3.2.1.- arabinan arabinan, arabinoxylan GH43 arabinan exo-a-1,2-L-arabinofuranosidase 3.2.1.- arabinan arabinan, arabinoxylan GH43 exo-alpha-1,5-L-arabinofuranosidase 3.2.1.- arabinan arabinan GH43 arabinan exo-a-1,3-L-arabinofuranosidase 3.2.1.- arabinan arabinan GH43 [inverting] endo-alpha-1,5-L-arabinanase 3.2.1.99 arabinan sulfated arabinan GH49 chaetomorphan endo-b-1,4-(3-sulfo)-arabinopyranosidase 3.2.1.- arabinan arabinan GH5 alpha-L-arabinofuranosidase 3.2.1.55 arabinan GH51 arabinan exo-a-1,2-L-arabinofuranosidase 3.2.1.- arabinan GH51 arabinan exo-a-1,3-L-arabinofuranosidase 3.2.1.- arabinan arabinan, arabinoxylan GH51 alpha-L-arabinofuranosidase 3.2.1.55 arabinan arabinan, arabinoxylan GH54 alpha-L-arabinofuranosidase 3.2.1.55 arabinan GH62 arabinan exo-a-1,3-L-arabinofuranosidase 3.2.1.- arabinan arabinoxylans, arabinogalactans, arabinan GH62 alpha-L-arabinofuranosidase 3.2.1.55 arabinan arabinan (pectin) GH93 exo-alpha-L-1,5-arabinanase 3.2.1.- arabinan GH97 b-L-arabinopyranosidase 3.2.1.88 arabinogalactan GH1 a-L-arabinopyranosidase 3.2.1.- arabinogalactan arabinogalactan GH115 alpha-(4-O-methyl)-glucuronidase 3.2.1.- arabinogalactan arabinogalactan proteins GH127 beta-L-arabinofuranosidase 3.2.1.185 arabinogalactan galactan GH147 arabinogalactan endo-b-1,4-galactosidase 3.2.1.89 arabinogalactan arabinogalactan proteins GH154 beta-1,6-D-glucuronidase 3.2.1.- arabinogalactan arabinogalactan proteins GH154 beta-glucuronidase 3.2.1.- arabinogalactan arabinogalactan proteins GH16 endo-beta-1,3-galactanase 3.2.1.181 arabinogalactan arabinan GH172 alpha-D-Fructofuranosidase 3.2.1.- arabinogalactan beta-galactan GH182 beta-D-galactofuranosidase 3.2.1.146 arabinogalactan arabinan GH183 endo-alpha-1,5-D-arabinofuranosidase 3.2.1.- arabinogalactan arabinogalactan GH27 beta-L-arabinopyranosidase 3.2.1.88 arabinogalactan GH30 arabinogalactan exo-b-1,6-galactobiosidase 3.2.1.- arabinogalactan arabinogalactan proteins GH30 endo-beta-1,6-galactanase 3.2.1.164 arabinogalactan GH39 arabinogalactan a-1,3-(arabinosyl)-L-arabinofuranosidase 3.2.1.- arabinogalactan GH39 arabinogalactan a-1,3-(galactosyl)-arabinofuranosidase 3.2.1.215 arabinogalactan beta-1,6/1,3-galactoside (arabinogalactan) GH42 beta-galactosidase 3.2.1.23 arabinogalactan beta-1,3-galactan, arabinogalactan GH43 exo-beta-1,3-galactanase 3.2.1.145 arabinogalactan arabinogalactan (bacteria) GH5 beta-D-galactofuranosidase 3.2.1.146 arabinogalactan arabinogalactan GH5 endo-beta-1,6-galactanase 3.2.1.164 arabinogalactan arabinogalactan GH53 endo-beta-1,4-galactanase 3.2.1.89 arabinogalactan arabinogalactan protein GH79 beta-4-O-methyl-glucuronidase 3.2.1.- arabinogalactan arabinogalactan protein GH79 beta-glucuronidase 3.2.1.31 arabinogalactan arabinogalactan PL42 L-rhamnose-alpha-1,4-D-glucuronate lyase 4.2.2.28 arabinoxylan;hemicellulose lignin CE15 Feruloyl esterase 3.1.1.73 bacterial outer membrane (OM) polysaccharides enterobacterial common antigen GT120 retaining undecapenyl-diphospho-oligosaccharyl transferase (O-antigen polymerase) 2.4.99.- bacterial outer membrane (OM) polysaccharides O-antigen lipopolysaccharide GT121 inverting undecapenyl-diphospho-oligosaccharyl transferase (O-antigen polymerase) 2.4.99.- bacterial outer membrane (OM) polysaccharides O-antigen lipopolysaccharide GT122 inverting undecapenyl-diphospho-oligosaccharyl transferase (O-antigen polymerase) 2.4.99.- bacterial outer membrane (OM) polysaccharides O-antigen lipopolysaccharide GT123 inverting undecapenyl-diphospho-oligosaccharyl transferase (O-antigen polymerase) 2.4.99.- bacterial outer membrane (OM) polysaccharides O-antigen lipopolysaccharide GT124 inverting undecapenyl-diphospho-oligosaccharyl transferase (O-antigen polymerase) 2.4.99.- bacterial outer membrane (OM) polysaccharides O-antigen lipopolysaccharide GT125 inverting undecapenyl-diphospho-oligosaccharyl transferase (O-antigen polymerase) 2.4.99.- bacterial outer membrane (OM) polysaccharides O-antigen lipopolysaccharide GT126 inverting undecapenyl-diphospho-oligosaccharyl transferase (O-antigen polymerase) 2.4.99.- bacterial outer membrane (OM) polysaccharides O-antigen lipopolysaccharide GT127 inverting undecapenyl-diphospho-oligosaccharyl transferase (O-antigen polymerase) 2.4.99.- bacterial outer membrane (OM) polysaccharides O-antigen lipopolysaccharide GT128 inverting undecapenyl-diphospho-oligosaccharyl transferase (O-antigen polymerase) 2.4.99.- bacterial outer membrane (OM) polysaccharides O-antigen lipopolysaccharide GT129 inverting undecapenyl-diphospho-oligosaccharyl transferase (O-antigen polymerase) 2.4.99.- bacterial outer membrane (OM) polysaccharides O-antigen lipopolysaccharide GT130 retaining undecapenyl-diphospho-oligosaccharyl transferase (O-antigen polymerase) 2.4.99.- bacterial outer membrane (OM) polysaccharides O-antigen lipopolysaccharide GT131 retaining undecapenyl-diphospho-oligosaccharyl transferase (O-antigen polymerase) 2.4.99.- bacterial outer membrane (OM) polysaccharides O-antigen lipopolysaccharide GT132 retaining undecapenyl-diphospho-oligosaccharyl transferase (O-antigen polymerase) 2.4.99.- bacterial outer membrane (OM) polysaccharides O-antigen lipopolysaccharide GT133 retaining undecapenyl-diphospho-oligosaccharyl transferase (O-antigen polymerase) 2.4.99.- bacterial outer membrane (OM) polysaccharides O-antigen lipopolysaccharide GT134 retaining undecapenyl-diphospho-oligosaccharyl transferase (O-antigen polymerase) 2.4.99.- bacterial outer membrane (OM) polysaccharides O-antigen lipopolysaccharide GT135 retaining undecapenyl-diphospho-oligosaccharyl transferase (O-antigen polymerase) 2.4.99.- bacterial outer membrane (OM) polysaccharides O-antigen lipopolysaccharide GT136 a-ribofuranosyltransferase activity on lipopolysaccharide O-antigen of the Citrobacter youngae protein ORF12 2.4.2.- bacterial outer membrane (OM) polysaccharides O-antigen lipopolysaccharide GT137 CMP-alpha-Kdo: alpha-Kdo transferase 2.4.99.- bacterial outer membrane (OM) polysaccharides PL1 poly a-D-N-acetylgalactosaminuric acid lyase 4.2.2.- beta-fucosides beta-fucosides GH1 beta-D-fucosidase 3.2.1.38 beta-fucosides GH3 b-fucosidase 3.2.1.38 beta-fucosides beta-fucosides GH30 beta-fucosidase 3.2.1.38 beta-fucosides alpha1,2-L-fucosidase sugar GH95 alpha-1,2-L-fucosidase 3.2.1.63 beta-galactan beta-1,4-galactan CBM61 Modules of approx. 150 residues found appended to GH16, GH30, GH31, GH43, GH53 and GH66 catalytic domains. A beta-1,4-galactan binding function has been demonstrated for the CBM61 of Thermotoga maritima GH53 galactanase [PMID: 20826814]. beta-galactan porphyran CBM99 porphyran binding property of several modules associated with GH86 and other CBM modules in Saccharobesus litoralis beta-galactan GH1 b-4,6-pyruvated-galactosidase 3.2.1.- beta-galactan beta-galactoside GH1 beta-galactosidase 3.2.1.23 beta-galactan GH1 ceramide b-galactosidase 3.2.1.46 beta-galactan 6-phospho-beta-galactoside GH1 6-phospho-beta-galactosidase 3.2.1.85 beta-galactan GH112 b-galactoside phosphorylase 2.4.1.- beta-galactan galactan GH147 beta-galactosidase 3.2.1.23 beta-galactan beta-galactoside GH159 beta-D-galactofuranosidase 3.2.1.146 beta-galactan GH16 galactan endo-b-1,4-galactosidase 3.2.1.- beta-galactan GH16 b-galactosidase 3.2.1.23 beta-galactan beta-galactoside GH165 beta-galactosidase 3.2.1.23 beta-galactan GH2 galactan exo-b-1,3-galactosidase 3.2.1.145 beta-galactan beta-galactoside GH2 beta-galactosidase 3.2.1.23 beta-galactan GH3 b-galactosidase 3.2.1.23 beta-galactan GH30 galactan exo-b-1,4-galactobiosidase 3.2.1.213 beta-galactan GH35 galactan exo-b-1,4-galactosidase 3.2.1.- beta-galactan beta-galactoside GH35 beta-galactosidase 3.2.1.23 beta-galactan beta-galactoside GH39 beta-galactosidase 3.2.1.23 beta-galactan beta-galactofuranoside GH43 beta-D-galactofuranosidase 3.2.1.146 beta-galactan GH5 b-galactosidase 3.2.1.23 beta-galactan GH54 b-galactosidase 3.2.1.23 beta-glucan glucooligosaccharide AA7 glucooligosaccharide oxidase 1.1.3.- beta-glucan laminarin CBM102 laminarin binding property of several CBM102 modules forming the GFO_3465 protein of Christiangramia forsetii KT0803 beta-glucan laminarin CBM103 laminarin binding property of the module associated to a GH16_3 in the GFO_3466 protein of Christiangramia forsetii KT0803 beta-glucan cellulose, mixed linked glucan CBM11 Modules of approx. 180-200 residues. The CBM11 of Clotridium thermocellum Cel26A-Cel5E has been shown to bind both beta-1,4-glucan and beta-1,3-1,4-mixed linked glucans. beta-glucan mutan CBM24 alpha-1,3-glucan (mutan)-binding function demonstrated in two cases (PMID:10636904) beta-glucan alpha-glucans amylose, amylopectin, pullulan, and oligosaccharide fragments derived from these polysaccharides CBM41 Modules of approx. 100 residues found in primarily in bacterial pullulanases. The N-terminal module from Thermotoga maritima Pul13 has been shown to bind to the alpha-glucans amylose, amylopectin, pullulan, and oligosaccharide fragments derived from these polysaccharides (Lammerts van Bueren et al. (2004) Biochemistry 43:15633-42) (PMID: 15581376). beta-glucan beta-1,3-glucan CBM43 Modules of approx. 90-100 residues found at the C-terminus of GH17 or GH72 enzymatic modules and also sometimes isolated. CBM43 modules sometimes carry a C-terminal membrane anchor. The beta-1,3-glucan binding function has been demonstrated with the olive pollen protein Ole e 10. beta-glucan beta-1,3-glucan CBM52 Modules of approx. 60 residues attached to a few GH81 enzymes but present in other proteins. Binding to beta-1,3-glucan demonstrated for Schizosaccharomyces pombe 972h- endo-1,3-beta-glucanase Eng1 [Martin-Quadrado et al., Mol. Microbiol. (2008) 69:188-200 PMID:18466295] beta-glucan beta-1,3-glucan CBM56 beta-1,3-glucan binding function demonstrated by Yamamoto et al. (1998) FEBS Letters 433:41-43 [PMID: 9738929] beta-glucan beta-glucans CBM79 Modules of approx. 130 residues found so far only in ruminococcal proteins. Binding to various beta-glucans was shown for the R. flavefaciens GH9 enzyme. beta-glucan beta-1,4-, beta-1,3,-glucans, xyloglucan, avicel and cellooligosaccharides CBM81 Small family of modules of approx. 100 residues, appended to GH5_2 enzymes. So far found exclusively in a few gammaproteobacteria. The CBM81 from an uncultivated species was shown to have binding affinity for beta-1,4-, beta-1,3,-glucans, xyloglucan, avicel and cellooligosaccharides. beta-glucan GH1 anthocyanin 5-O-glucosyltransferase / 5-O-transglucosidase 2.4.1.- beta-glucan GH1 anthocyanin 7-O-glucosyltransferase / 7-O-transglucosidase 2.4.1.- beta-glucan GH1 b-transglucosidase 2.4.1.- beta-glucan GH1 glucan exo-b-1,2-glucosidase 3.2.1.- beta-glucan GH1 a-neuraminidase 3.2.1.18 beta-glucan GH1 avenacosidase 26-O-b-glucosidase 3.2.1.188 beta-glucan GH1 oleuropein b-glucosidase 3.2.1.206 beta-glucan beta-glucoside GH1 beta-glucosidase 3.2.1.21 beta-glucan ceramide b-galactosidase GH1 ceramide b-glucosidase 3.2.1.45 beta-glucan GH1 glucan exo-b-1,3-glucosidase 3.2.1.58 beta-glucan beta-glucoside GH1 exo-beta-1,4-glucanase 3.2.1.74 beta-glucan 6-phospho-beta-glucoside GH1 6-phospho-beta-glucosidase 3.2.1.86 beta-glucan cellulose, xylan, beta-1,4-glucan GH10 endo-beta-1,4-glucanase 3.2.1.4 beta-glucan mixed-linkage glucan GH12 beta-1,3-1,4-glucanase 3.2.1.73 beta-glucan beta-1,3-glucan (bacteria, fungi, plant, algae) GH128 beta-1,3-glucanase 3.2.1.39 beta-glucan beta-1,3-glucan (bacteria, fungi, plant, algae) GH128 beta-1,3-glucosidase 3.2.1.58 beta-glucan beta-glucans, including laminarin, curdlan, pachyman, lichenan, pustulan, and cellulosic derivatives GH131 beta-glucosidase 3.2.1.21 beta-glucan GH131 glucan exo-b-1,3-glucosidase 3.2.1.58 beta-glucan beta-1,3-glucan (fungi) GH132 beta-1,3-glucosidase 3.2.1.58 beta-glucan beta-1,2-glucan (bacteria) GH144 beta-1,2-glucooligosaccharide sophorohydrolase 3.2.1.214 beta-glucan beta-1,2-glucan (bacteria) GH144 endo-beta-1,2-glucanase 3.2.1.71 beta-glucan beta-glucan and lichenin GH148 beta-1,3-glucanase 3.2.1.- beta-glucan GH148 MLG endo-b-1,4-glucosidase 3.2.1.73 beta-glucan beta-1,3-glucan GH149 beta-1,3-glucan phosphorylase 2.4.1.97 beta-glucan beta-1,3-glucan (fungal lentinan) GH152 beta-1,3-glucanase 3.2.1.39 beta-glucan beta-glucans (bacteria curdlan) GH157 endo-beta-1,3-glucanase / laminarinase 3.2.1.39 beta-glucan beta-glucans (yeast, seaweed, and plant) GH158 endo-beta-1,3-glucanase 3.2.1.39 beta-glucan beta-1,3-glucan GH16 beta-transglycosidase 2.4.1.- beta-glucan GH16 b-1,3-glucanosyltransglucosidase 2.4.1.- beta-glucan GH16 b-glucosidase 3.2.1.21 beta-glucan beta-1,3-glucan (fungi, algae, plant) GH16 endo-1,3-beta-glucanase / laminarinase 3.2.1.39 beta-glucan GH16 glucan exo-b-1,3-glucosidase 3.2.1.58 beta-glucan beta-1,3-1,4-glucan (laminarin, lichenin and cereal D-glucans) GH16 endo-1,3(4)-beta-glucanase 3.2.1.6 beta-glucan beta-1,3-1,4-glucan (laminarin, lichenin and cereal D-glucans) GH16 licheninase 3.2.1.73 beta-glucan beta-1,3-glucan (fungi, algae, plant) GH161 beta-1,3-glucan phosphorylase 2.4.1.97 beta-glucan beta-1,2-glucan (bacteria) GH162 endo-beta-1,2-glucanase 3.2.1.71 beta-glucan beta-1,3-glucan (fungi, algae, plant) GH17 beta-1,3-glucanosyltransglycosylase 2.4.1.- beta-glucan GH17 laminarin b-1,6-glucanosyltransglucosidase 2.4.1.- beta-glucan beta-1,3-glucan (algae, plant) GH17 glucan endo-1,3-beta-glucosidase 3.2.1.39 beta-glucan beta-1,3-glucan (fungi) GH17 beta-1,3-glucosidase 3.2.1.58 beta-glucan beta-1,3-1,4-glucan (laminarin, lichenin and cereal D-glucans) GH17 licheninase 3.2.1.73 beta-glucan beta-glucosidase GH175 beta-glucosidase 3.2.1.21 beta-glucan p-nitrophenyl-_-D-glucopyranoside (p-NPG) and cellobiose GH180 beta-glucosidase 3.2.1.21 beta-glucan beta-glucan GH186 endo-b-1,2-glucanase activity of the OpgG and OpgD proteins in Escherichia coli BL21(DE3) 3.2.1.71 beta-glucan beta-1,2-glucan GH189 b-1,2-glucan synthetase (elongation) 2.4.1.391 beta-glucan beta-1,2-glucan GH189 b-1,2-glucan synthetase (cyclization) 2.4.1.397 beta-glucan GH192 glucan endo-b-1,2-glucosidase 3.2.1.71 beta-glucan GH193 glucan endo-b-1,2-glucosidase 3.2.1.71 beta-glucan GH194 glucan endo-b-1,2-glucosidase 3.2.1.71 beta-glucan beta-glucoside GH2 beta-glucosidase 3.2.1.21 beta-glucan beta-glucan GH26 lichenase / endo-beta-1,3-1,4-glucanase 3.2.1.73 beta-glucan GH3 b-glucoside phosphorylase 2.4.1.- beta-glucan GH3 b-glucoside phosphorylase 2.4.1.- beta-glucan avenacin GH3 avenacin b-1,2-glucosidase 3.2.1.- beta-glucan avenacin GH3 avenacin b-1,4-glucosidase 3.2.1.- beta-glucan beta-1,3-1,4-glucan (laminarin, lichenin and cereal D-glucans) GH3 MLG exo-b-1,3/4-glucosidase 3.2.1.- beta-glucan GH3 unsaturated-b-glucuronidase 3.2.1.- beta-glucan GH3 a-L-arabinopyranosidase 3.2.1.- beta-glucan GH3 glucan exo-b-1,2-glucosidase 3.2.1.- beta-glucan GH3 MLG exo-b-1,4-glucosidase 3.2.1.- beta-glucan beta-glucan GH3 beta-glucosidase 3.2.1.21 beta-glucan GH3 glucan exo-b-1,3-glucosidase 3.2.1.58 beta-glucan GH3 MLG endo-b-1,3/4-glucosidase 3.2.1.6 beta-glucan beta-1,3-glucan (laminarin, lichenin and cereal D-glucans) GH3 lichenase / endo-beta-1,3-1,4-glucanase 3.2.1.73 beta-glucan cellodextrin (beta-1,3-glucan) GH3 glucan 1,4-beta-glucosidase 3.2.1.74 beta-glucan beta-glucan GH30 beta-glucosidase 3.2.1.21 beta-glucan beta-1,6-glucan (fungal and algal cell wall) GH30 beta-1,6-glucanase 3.2.1.75 beta-glucan GH35 b-1,2-glucan synthetase (elongation) 2.4.1.391 beta-glucan GH35 glucan exo-b-1,2-glucobiosidase 3.2.1.214 beta-glucan beta-glucoside (exopolysaccharide, cellubiose) GH39 beta-glucosidase 3.2.1.21 beta-glucan isomaltulose (palatinose, from honey and sugar cane) GH4 MLG endo-b-1,3/4-glucosidase 3.2.1.6 beta-glucan beta-glucoside (sinigrin, cellubiose) GH4 6-phospho-beta-glucosidase 3.2.1.86 beta-glucan cellulose, lichenin and cereal beta-glucan GH44 endoglucanase 3.2.1.4 beta-glucan GH44 MLG endo-b-1,4-glucosidase 3.2.1.73 beta-glucan cellulose, lichenin and cereal beta-glucan GH45 endoglucanase 3.2.1.4 beta-glucan beta-glycoside GH5 MLG endo-b-1,3-glucosidase 3.2.1.- beta-glucan beta-glycoside GH5 beta-primeverosidase 3.2.1.149 beta-glucan laminarin (algae), pustulan (fungi) GH5 endo-beta-1,3-glucanase / laminarinase 3.2.1.39 beta-glucan cellulose, beta-glucan GH5 endo-beta-1,4-glucanase / cellulase 3.2.1.4 beta-glucan beta-1,3-glucans (laminarin) GH5 glucan beta-1,3-glucosidase 3.2.1.58 beta-glucan GH5 MLG endo-b-1,3/4-glucosidase 3.2.1.6 beta-glucan beta-glucan(contains both (1->3)- and (1->4)-bonds),lichenin and cereal beta-glucan GH5 lichenase / endo-beta-1,3-1,4-glucanase 3.2.1.73 beta-glucan laminarin (algae), pustulan (fungi) GH5 glucan endo-1,6-beta-glucosidase 3.2.1.75 beta-glucan cellulose, beta-glucan GH51 cellulose endo-b-1,4-glucosidase 3.2.1.4 beta-glucan GH51 MLG endo-b-1,3/4-glucosidase 3.2.1.6 beta-glucan laminarin (algae) GH55 laminarin-degrading enzyme 3.2.1.- beta-glucan laminarin (algae), pustulan (fungi) GH55 endo-beta-1,3-glucanase 3.2.1.39 beta-glucan laminarin (algae), pustulan (fungi) GH55 exo-beta-1,3-glucanase 3.2.1.58 beta-glucan beta-1,4-glucan, glycogen GH57 branching enzyme 2.4.1.18 beta-glucan beta-1,3-glucan (fungal cell walls) GH64 beta-1,3-glucanase 3.2.1.39 beta-glucan beta-1,3-glucan GH72 beta-1,3-glucanosyltransglycosylase 2.4.1.- beta-glucan beta-glucan (laminarin, lichenin and cereal D-glucans) GH8 endo-beta-1,3(4)-glucanase / lichenase-laminarinase 3.2.1.6 beta-glucan beta-glucan (lichenin and cereal beta-glucan) GH8 licheninase 3.2.1.73 beta-glucan beta--1,3-glucan GH81 endo-beta-1,3-glucanase 3.2.1.39 beta-glucan xanthan GH9 endo-beta-1,4-glucanase (xanthanase) 3.2.1.- beta-glucan xyloglucan GH9 xyloglucan-specific endo-beta-1,4-glucanase / endo-xyloglucanase 3.2.1.151 beta-glucan beta-glucan(laminarin, lichenin and cereal D-glucans) GH9 endo-beta-1,3(4)-glucanase / lichenase-laminarinase 3.2.1.6 beta-glucan beta-glucan, lichenin GH9 lichenase / endo-beta-1,3-1,4-glucanase 3.2.1.73 beta-glucan GH94 b-1,4-mixed linkage glucan phosphorylase 2.4.1.- beta-glucan laminarin GH94 laminaribiose phosphorylase 2.4.1.31 beta-glucan 1,2-beta-oligoglucan GH94 beta--1,2-oligoglucan phosphorylase 2.4.1.333 beta-glucan;beta-mannan galactoxyloglucan and galactomannan CBM88 Binding to terminal galactose in galactoxyloglucan and galactomannan beta-glucan;beta-mannan;cellulose;xylan glycans (cellulose, glucuronoxylan, b-1,3-1,4-glucan and glucomannan) CBM85 Created after Fredriksen et al. (2019) PMID=30635385; binds to a broad range of glycans (cellulose, glucuronoxylan, b-1,3-1,4-glucan and glucomannan) beta-glucan;beta-mannan;xylan broad spectrum of polysaccharides including soluble and insoluble cellulose, beta-1,3/1,4-mixed linked glucans, xylan, and beta-mannan CBM72 Modules of 130-180 residues found at the C-terminus glycoside hydrolases from various families, sometimes as tandem repeats. The CBM72 found on an endoglucanase from an uncultivated microorganism was found to bind a broad spectrum of polysaccharides including soluble and insoluble cellulose, beta-1,3/1,4-mixed linked glucans, xylan, and beta-mannan [PMID=26765840]. beta-glucan;beta-mannan;xyloglucan beta-glycans (xyloglucan, glucomannan, galactomannan, barley beta-glucan) CBM80 Modules of approx. 90 residues found so far only in ruminococcal enzymes of families GH5 or GH26. Broad specificity for beta-glycans (xyloglucan, glucomannan, galactomannan, barley beta-glucan). beta-glucan;carrageenan carrageenan, b-1,3-glucan, b-1,6-glucan CBM92 Carrageenan binding activity was reported for the module of Cgk16A protein in Wenyingzhuangia sp. OF219 (AST13124.1) [PubMed=35830544] beta-glucan;cellulose;xylan amorphous cellulose, beta-1,4-xylan,beta-1,3-glucan, beta-1,3-1,4-glucan, and beta-1,4-glucan CBM6 Modules of approx. 120 residues. The cellulose-binding function has been demonstrated in one case on amorphous cellulose and beta-1,4-xylan. Some of these modules also bind beta-1,3-glucan, beta-1,3-1,4-glucan, and beta-1,4-glucan. beta-glucan;exo-polysaccharide archaea exo-polysaccharide (EPS) GH116 beta-xylosidase 3.2.1.37 beta-glucan;lipopolysaccharide beta-1,3-glucan,lipopolysaccharide and lipoteichoic acid CBM39 Modules generally found at the N-terminus of a GH16 module (itself frequently lacking a catalytic machinery) and more seldomly in isolation. The beta-1,3-glucan binding function has been demonstrated, along with binding to lipopolysaccharide and lipoteichoic acid. beta-glucan;xyloglucan beta-1,4-glucans CBM78 Modules of approx. 150 residues appended to the C-terminus of GH5 and GH26 enzymes. So far found exclusively in Ruminococcal enzymes. The R. flavefaciens module has been shown to bind decorated beta-1,4-glucans with a preference for xyloglucan. beta-glucuronan beta-glucuronoside GH1 beta-glucuronidase 3.2.1.31 beta-glucuronan beta-glucuronoside GH2 beta-glucuronidase 3.2.1.31 beta-glucuronan GH3 b-glucuronidase 3.2.1.31 beta-glucuronan GH94 b-1,3-glucosyl-glucuronic acid phosphorylase 2.4.1.392 beta-glucuronan;alginate beta-glucuronan; alginate PL14 beta-1,4-glucuronan lyase 4.2.2.14 beta-glucuronan;alginate beta-glucuronan; alginate PL20 endo-beta-1,4-glucuronan lyase 4.2.2.14 beta-glucuronan;alginate beta-glucuronan; alginate PL31 endo-beta-1,4-glucuronan lyase 4.2.2.14 beta-glucuronan;alginate beta-glucuronan; alginate PL38 endo-beta-1,4-glucuronan lyase 4.2.2.14 beta-glucuronan;alginate beta-glucuronan; alginate PL5 endo-beta-1,4-glucuronan lyase 4.2.2.14 beta-glucuronan;alginate beta-glucuronan; alginate PL7 endo-beta-1,4-glucuronan lyase 4.2.2.14 beta-glucuronan;alginate PL8 exo-b-1,4-glucuronan lyase 4.2.2.- beta-mannan mannan CBM23 Mannan-binding function demonstrated in one case. beta-mannan mannan CBM27 Mannan-binding function demonstrated in two cases beta-mannan mannan,glucomannan CBM29 Binding to mannan/glucomannan has been demonstrated. beta-mannan beta-mannoside GH1 beta-mannosidase 3.2.1.25 beta-mannan GH113 reducing end mannan exo-b1,4-mannosidase 3.2.1.- beta-mannan GH113 b-mannosidase 3.2.1.25 beta-mannan beta-mannan GH113 beta-mannanase 3.2.1.78 beta-mannan mannooligosaccharides GH130 beta-mannoside phosphorylase 2.4.1.- beta-mannan beta-mannan GH130 beta-1,3-mannan phosphorylase 2.4.1.- beta-mannan beta-mannan GH130 beta-1,4-mannosylglucose phosphorylase 2.4.1.281 beta-mannan beta-mannan GH130 beta-1,4-mannooligosaccharide phosphorylase 2.4.1.319 beta-mannan beta-mannan GH130 beta-1,4-mannosyl-N-acetyl-glucosamine phosphorylase 2.4.1.320 beta-mannan beta-mannan GH130 beta--1,2-mannobiose phosphorylase 2.4.1.339 beta-mannan beta-mannan GH130 beta--1,2-oligomannan phosphorylase 2.4.1.340 beta-mannan beta-mannan GH130 beta-1,2-mannosidase 3.2.1.197 beta-mannan beta-mannan GH134 endo-beta-1,4-mannanase 3.2.1.78 beta-mannan glucomannan GH148 beta-1,3-glucanase 3.2.1.4 beta-mannan beta-mannoside GH164 beta-mannosidase 3.2.1.25 beta-mannan beta-mannoside GH2 beta-mannosidase 3.2.1.25 beta-mannan beta-mannan (plant) GH26 exo-beta-1,4-mannobiohydrolase 3.2.1.100 beta-mannan beta-mannan (plant) GH26 beta-mannanase 3.2.1.78 beta-mannan GH27 galactomannan exo-a-1,6-galactosidase 3.2.1.- beta-mannan mannans, galactomannans and glucomannan GH45 glucomannan endo-b-1,4-glucosidase 3.2.1.- beta-mannan beta-mannan GH5 glucomannan exo-b-1,3-mannosidase 3.2.1.- beta-mannan glucomannan GH5 glucomannan-specific endo-beta-1,4-glucanase 3.2.1.- beta-mannan GH5 mannan exo-b-1,4-mannosidase 3.2.1.- beta-mannan N-glycan, beta-mannan GH5 beta-mannosidase 3.2.1.25 beta-mannan mannans, galactomannans and glucomannan GH5 mannan endo-beta-1,4-mannosidase 3.2.1.78 beta-mannan;cellulose;xylan mannan, xylan, and cellulose CBM59 Binding to mannan, xylan, and cellulose demonstrated for the CBM59 of ManF-X10 xylanase from an environmental genomic DNA library (Li et al. (2009) World Journal of Microbiology and Biotechnology 25:2071-2078,doi:10.1007/s11274-009-0111-6) carrageenan carrageenan (marine algae) GH127 b-carrageenan exo-a-1,3-anhydro-galactosidase 3.2.1.- carrageenan carrageenan (marine algae) GH129 alpha-1,3-(3,6)-anhydro-D-galactosidase 3.2.1.- carrageenan carrageenan GH150 Iota-carrageenase 3.2.1.162 carrageenan carrageenan GH16 beta-carrageenase 3.2.1.- carrageenan carrageenan GH16 kappa-carrageenase 3.2.1.83 carrageenan GH167 k-neocarrageen exo-b-1,4-(4-sulfo)-galactobiosidase 3.2.1.- carrageenan carrageenan GH167 beta-carrageenase 3.2.1.- carrageenan iota-carrageenans GH82 ι-carrageenase 3.2.1.157 cellulose cellulose AA10 lytic cellulose monooxygenase (C1-hydroxylating) 1.14.99.54 cellulose cellulose AA10 lytic cellulose monooxygenase (C4-dehydrogenating) 1.14.99.56 cellulose cellulose AA15 lytic cellulose monooxygenase (C1-hydroxylating) 1.14.99.54 cellulose cellulose AA16 Lytic cellulose monooxygenase (C1-hydroxylating) 1.14.99.54 cellulose cellulose AA18 lytic cellulose monooxygenase 1.14.99.54 cellulose cellulose AA3 cellobiose dehydrogenase 1.1.99.18 cellulose cellooligosaccharide AA7 cellooligosaccharide dehydrogenase 1.1.99.- cellulose cellulose AA9 lytic xylan monooxygenase / xylan oxidase (C1-hydroxylating) 1.14.99.- cellulose cellulose AA9 lytic cellulose monooxygenase (C1-hydroxylating) 1.14.99.54 cellulose cellulose AA9 lytic cellulose monooxygenase (C4-dehydrogenating) 1.14.99.56 cellulose cellulose CBM10 Modules of approx. 50 residues. The cellulose-binding function has been demonstrated in one case. cellulose CBM104 native crystalline cellulose binding cellulose amorphous cellulose, cellooligosaccharides and derivatized cellulose CBM17 Modules of approx. 200 residues. Binding to amorphous cellulose, cellooligosaccharides and derivatized cellulose has been demonstrated. cellulose non-crystalline cellulose, cellooligosaccharides, and beta-(1,3)(1,4)-glucans CBM28 The module from the endo-1,4-glucanase of Bacillus sp. 1139 binds to non-crystalline cellulose, cellooligosaccharides, and beta-(1,3)(1,4)-glucans cellulose cellulose CBM30 Binding to cellulose has been demonstrated for the N-terminal module of Fibrobacter succinogenes CelF. cellulose cellulose CBM46 Modules of approx. 100 residues, found at the C-terminus of several GH5 cellulases. Cellulose-binding function demonstrated in one case. cellulose crystalline cellulose CBM49 Modules of approx. 100 residues found at the C-terminus of plant GH9 enzymes. Distantly related to CBM2 modules. Binding to crystalline cellulose demonstrated in the case of Solanum lycopersicum Cel8 enzyme (SlCel9C1). cellulose cellulose CBM63 The CBM63 module of Bacillus subtilis expansin EXLX1 has been shown to bind cellulose. cellulose cellulose CBM64 Module found at C-term of several Spirochaeta thermophila proteins. Binding to cellulose shown by Angelov, Loderer, Pompei Liebl (2011) AEM, 77:5483-5489 [PMID - 21685171] cellulose cellulose CBM8 The cellulose-binding module from a cellulase of the slime mold Dictyostelium discoideum has been experimentally shown to bind cellulose. cellulose cellulose CBM9 Modules of approx. 170 residues found so far only in xylanases. The cellulose-binding function has been demonstrated in one case. cellulose cellulose, beta-glucan GH12 endoglucanase 3.2.1.4 cellulose cellulose GH124 endoglucanase 3.2.1.4 cellulose GH26 cellulose endo-b-1,4-glucosidase 3.2.1.4 cellulose beta-glucoside (cellubiose) GH39 exo-beta-1,4-glucanase / cellodextrinase 3.2.1.74 cellulose cellulose GH48 reducing end-acting cellobiohydrolase 3.2.1.176 cellulose cellulose GH48 endo-beta-1,4-glucanase 3.2.1.4 cellulose GH48 cellulose exo-b-1,4-glucobiosidase 3.2.1.91 cellulose cellulose and similar substrates GH5 exo-beta-1,4-glucanase / cellodextrinase 3.2.1.74 cellulose cellulose GH5 cellulose beta-1,4-cellobiosidase 3.2.1.91 cellulose GH51 cellulose exo-b-1,4-glucobiosidase 3.2.1.91 cellulose cellulose GH6 cellulose endo-b-1,4-glucosidase 3.2.1.4 cellulose cellulose GH6 lichenase / endo-beta-1,3-1,4-glucanase 3.2.1.73 cellulose cellulose GH6 cellobiohydrolase 3.2.1.91 cellulose cellulose and similar substrates GH7 reducing end-acting cellobiohydrolase 3.2.1.176 cellulose cellulose, lichenin and cereal beta-glucan GH7 endo-beta-1,4-glucanase 3.2.1.4 cellulose beta-glucan, lichenin GH7 endo-beta-1,3-1,4-glucanase 3.2.1.73 cellulose carboxymethyl cellulose GH74 endoglucanase 3.2.1.4 cellulose cellulose GH8 cellulase 3.2.1.4 cellulose cellulose GH9 endoglucanase 3.2.1.4 cellulose cellulose GH9 exo-beta-1,4-glucanase / cellodextrinase 3.2.1.74 cellulose cellulose and cellotetraose GH9 cellobiohydrolase 3.2.1.91 cellulose cellobiose GH94 cellobiose phosphorylase 2.4.1.20 cellulose cellobionic acid GH94 cellobionic acid phosphorylase 2.4.1.321 cellulose cellodextrin GH94 cellodextrin phosphorylase 2.4.1.49 cellulose;beta-mannan cellulose and glucomannan CBM16 Carbohydrate-binding module 16. Binding to cellulose and glucomannan demonstrated [B. Bae et al (2008) J Biol Chem. 283:12415-25 (PMID: 18025086)] cellulose;chitin cellulose, chitin CBM1 Modules of approx. 40 residues found almost exclusively in fungi. The cellulose-binding function has been demonstrated in many cases, and appears to be mediated by three aromatic residues separated by about 10.4 angstrom and which form a flat surface. The only non-fungal occurence of CBM1 is in an algal non-hydrolytic polysaccharide-binding protein which is composed of four repeated CBM1 modules. Binding to chitin has been demonstrated in one case. cellulose;chitin cellulose,chitin CBM3 Modules of approx. 150 residues found in bacterial enzymes. The cellulose-binding function has been demonstrated in many cases. In one instance binding to chitin has been reported. cellulose;chitin;xylan cellulose, chitin, xylan CBM2 Modules of approx. 100 residues and which are found in a large number of bacterial enzymes. The cellulose-binding function has been demonstrated in many cases. Several of these modules have been shown to also bind chitin or xylan. cellulose;xyloglucan cellulose and xyloglucan CBM44 The C-terminal CBM44 module of the Clostridium thermocellum enzyme has been demonstrated to bind equally well cellulose and xyloglucan cephalosporin C cephalosporin C(antibiotic) CE7 cephalosporin-C deacetylase 3.1.1.41 chitin chitin AA10 lytic chitin monooxygenase 1.14.99.53 chitin chitin AA11 lytic chitin monooxygenase 1.14.99.53 chitin chitin AA15 lytic chitin monooxygenase 1.14.99.53 chitin chitooligosaccharide AA7 chitooligosaccharide oxidase 1.1.3.- chitin chitin CBM12 Modules of approx. 40-60 residues. The majority of these modules is found among chitinases where the function is chitin-binding. Distantly related to the CBM5 family. chitin chitin CBM14 Modules of approx. 70 residues. The chitin-binding function has been demonstrated in several cases. These modules are found attached to a number of chitinase catalytic domains, but also in non-catalytic proteins either in isolation or as multiple repeats chitin chitin CBM18 Modules of approx. 40 residues. The chitin-binding function has been demonstrated in many cases. These modules are found attached to a number of chitinase catalytic domains, but also in non-catalytic proteins either in isolation or as multiple repeats. chitin chitin CBM19 Modules of 60-70 residues with chitin-binding function. chitin chitin CBM5 Modules of approx. 60 residues found in bacterial enzymes. Chitin-binding described in several cases. Distantly related to the CBM12 family. chitin chitin CBM55 Binding to chitin demonstrated in the case of the CBM55 of Entamoeba histolytica chitinase (Van Dellen et al. (2002) Infect Immun. 70:3259-3263,PMID: 12011021). chitin chitin CBM73 Modules of approx 65 residues found on various enzymes active of chitin. Chitin-binding function demonstrated for the Cellvibrio japonicus CjLPMO10A protein. chitin chitin CE14 diacetylchitobiose deacetylase 3.5.1.- chitin chitin CE14 chitin disaccharide deacetylase(RE) 3.5.1.105 chitin alkylating agents and xenobiotics(organic compound) CE14 mycothiol S-conjugate amidase 3.5.1.115 chitin alkylating agents and xenobiotics(organic compound) CE14 Chitin disaccharide deacetylase (NRE) 3.5.1.136 chitin alkylating agents and xenobiotics(organic compound) CE14 N-acetylglucosamine deacetylase 3.5.1.33 chitin Chitooligosaccharides CE4 chitooligosaccharide deacetylase 3.1.1.- chitin chitin CE4 chitin deacetylase 3.5.1.41 chitin chitin GH16 chitin beta-1,6-glucanosyltransferase 2.4.1.- chitin chitooligosaccharides (symbiotic nitrogen-fixing bacteria) GH18 Nod factor hydrolase 3.2.1.- chitin GH18 chitin exo-b-1,4-N-acetylglucosaminidase 3.2.1.- chitin GH18 chitosan endo-b-1,4-N-glucosaminase 3.2.1.132 chitin chitin GH18 chitinase 3.2.1.14 chitin GH18 chitin exo-b-1,4-N-acetylglucobiosaminidase 3.2.1.200 chitin GH18 reducing end chitin exo-b-1,4-N-acetylglucosaminidase 3.2.1.201 chitin chitin GH19 chitinase 3.2.1.14 chitin chitin GH19 reducing end chitin exo-b-1,4-N-acetylglucosaminidase 3.2.1.201 chitin chitin GH23 chitinase 3.2.1.14 chitin chitin, peptidoglycan GH3 beta-N-acetylhexosaminidase 3.2.1.52 chitin chitosan, chitin GH35 exo-beta-glucosaminidase 3.2.1.165 chitin chitin and chitodextrin GH48 chitinase 3.2.1.14 chitin 4-O-beta--glucosyl-galactose GH94 b-1,4-glucosyl-galactose phosphorylase 2.4.1.- chitin chitin GH94 chitobiose phosphorylase 2.4.1.280 chitin;peptidoglycan chitin or peptidoglycan CBM50 Modules of approx. 50 residues found attached to various enzymes from families GH18, GH19, GH23, GH24, GH25 and GH73, i.e. enzymes cleaving either chitin or peptidoglycan. Binding to chitopentaose demonstrated in the case of Pteris ryukyuensis chitinase A [Ohnuma T et al. (2008) J. Biol. Chem. 283:5178-87 (PMID: 18083709)]. CBM50 modules are also found in a multitude of other enzymes targeting the petidoglycan such as peptidases and amidases. These enzymes are not reported in the list below. chitin;peptidoglycan chitin or peptidoglycan GH179 beta-N-acetylhexosaminidase (favor GlcNAc) 3.2.1.52 chitin;peptidoglycan chitin or peptidoglycan GH5 beta-N-acetylhexosaminidase 3.2.1.52 chitosan chitosan or chitosan oligosaccharides (nonacetylated chitin) GH2 exo-beta-glucosaminidase 3.2.1.165 chitosan GH3 chitosan endo-b-1,4-N-glucosaminase 3.2.1.132 chitosan chitosan GH46 chitosanase 3.2.1.132 chitosan chitosan GH5 chitosanase 3.2.1.132 chitosan chitosan GH7 chitosanase 3.2.1.132 chitosan chitosan GH75 chitosanase 3.2.1.132 chitosan chitosan GH8 chitosanase 3.2.1.132 chitosan chitosan GH80 chitosanase 3.2.1.132 chitosan chitosan or chitosan oligosaccharides GH9 exo-beta-glucosaminidase 3.2.1.165 exo-polysaccharide biosynthesis of lipid A CE11 UDP-3-0-acyl N-acetylglucosamine deacetylase 3.5.1.108 exo-polysaccharide glycosylphosphatidylinositol(lipid anchor ) CE14 N-acetylglucosaminylphosphatidylinositol deacetylase 3.5.1.89 exo-polysaccharide exo-polysaccharide of biofilm CE21 N-acetylgalactosamine deacetylase 3.1.1.58 exo-polysaccharide human bile acid, archaea exo-polysaccharide (EPS) GH116 beta-glucosidase 3.2.1.21 exo-polysaccharide archaea exo-polysaccharide (EPS) GH116 beta-N-acetylglucosaminidase 3.2.1.52 exo-polysaccharide deacetylated poly-beta-(1,6)-N-acetyl-glucosamine (bacterial PNAG for biofilm) GH153 poly-beta-1,6-D-glucosamine hydrolase 3.2.1.- exo-polysaccharide exopolysaccharides (bacteria) GH16 MLG endo-b-1,3-glucosidase 3.2.1.- exo-polysaccharide Nostoc commune EPS GH160 endo-beta-1,4-galactosidase 3.2.1.- exo-polysaccharide capsular polysaccharide (bacteria) GH169 beta-1,4-D-glucuronidase 3.2.1.- exo-polysaccharide capsular polysaccharide (bacteria) GH20 beta-1,6-N-acetylglucosaminidase 3.2.1.- exo-polysaccharide glucopyranosyl-alpha-1,3-rhamnose (bacteria lipopolysaccharides or capsule polysaccharides) GH65 3-O-alpha-glucopyranosyl-L-rhamnose phosphorylase 2.4.1.282 exo-polysaccharide lipo- or capsular polysaccharides GH90 LPS endo-a-1,3-rhamnosidase 3.2.1.- fructan inulin CBM38 The inulin-binding function has been demonstrated in the case of the cycloinulo-oligosaccharide fructanotransferase from Paenibacillus macerans (Bacillus macerans) by Lee et al. (2004) FEMS Microbiol Lett 234:105-10. (PMID:15109727). fructan fructan CBM66 The CBM66 module, derived from the Bacillus subtilis exo-acting beta-fructosidase SacC, targets the terminal fructoside residue of fructans. fructan fructooligosaccharides GH172 difructose-anhydride-I synthase 4.2.1.179 fructan levan (fructan) GH32 levan fructosyltransferase 2.4.1.- fructan graminan- and levan-type fructans GH32 [retaining] sucrose:sucrose 6-fructosyltransferase (6-SST) 2.4.1.- fructan fructan(inulin, levan and sucrose) GH32 cycloinulo-oligosaccharide fructanotransferase 2.4.1.- fructan fructan(inulin, levan and sucrose) GH32 sucrose:fructan 6-fructosyltransferase 2.4.1.10 fructan fructan(inulin, levan and sucrose) GH32 fructan:fructan 1-fructosyltransferase 2.4.1.100 fructan fructan(inulin, levan and sucrose) GH32 fructan:fructan 6G-fructosyltransferase 2.4.1.243 fructan fructan(inulin, levan and sucrose) GH32 sucrose:sucrose 1-fructosyltransferase 2.4.1.99 fructan GH32 6-kesose b-2,6-fructose 3.2.1.- fructan fructan GH32 fructan beta-(2,1)-fructosidase/1-exohydrolase 3.2.1.153 fructan fructan GH32 fructan beta-(2,6)-fructosidase/6-exohydrolase 3.2.1.154 fructan fructan(inulin, levan and sucrose) GH32 invertase 3.2.1.26 fructan fructan(inulin, levan and sucrose) GH32 beta-2,6-fructan 6-levanbiohydrolase 3.2.1.64 fructan levan (fructan) GH32 endo-levanase 3.2.1.65 fructan inulin GH32 endo-inulinase 3.2.1.7 fructan synthesize beta-(2-6)-linked fructan levan with sucrose as substrate GH68 levansucrase 2.4.1.10 fructan synthesize beta-(2-1)-linked fructan GH68 inulosucrase 2.4.1.9 fructan synthesize beta-(2-1)-linked fructan GH68 beta-fructofuranosidase 3.2.1.26 fructan inulin GH91 difructofuranose 1,2':2,3' dianhydride hydrolase [DFA-IIIase] 3.2.1.- fructan inulin GH91 inulin lyase [DFA-I-forming] 4.2.2.17 fructan inulin GH91 inulin lyase [DFA-III-forming] 4.2.2.18 fucoidan GH107 fucoidan endo-a-1,3-(2-sulfo)-fucosidase 3.2.1.211 fucoidan fucoidan (brown algae) GH107 endo-alpha-1,4-L-fucanase 3.2.1.212 fucoidan GH168 fucoidan (Ib) endo-a-1,3-L-fucosidase 3.2.1.- fucoidan sulfated fucans (algae) GH168 endo-alpha-(1,3)-L-fucanase 3.2.1.211 fucoidan fucoidan GH174 fucoidan (Ib) endo-a-1,3-L-fucosidase 3.2.1.- fucoidan sulfated fucans (algae) GH187 endo-a-1,3-L-fucanase activity of the Fun187A protein in Wenyingzhuangia aestuarii OF219 3.2.1.- fucoidan fucoidan (brown algae) PL43 fucoidan lyase 4.2.2.- funoran GH96 funoran endo-a-1,3-anhydro-L-galactosidase 3.2.1.222 galactan raffinose family oligosaccharide (plant) GH27 galactan:galactan galactosyltransferase 2.4.1.- galactosaminogalactan galactosaminogalactan CBM87 Binding to alpha-1,4-N-acetylgalactosamine-rich regions of galactosaminogalactan galactosaminogalactan galactosaminogalactan (fungal exopolysaccharide) GH114 endo-alpha-1,4-polygalactosaminidase 3.2.1.109 galactosaminogalactan exopolysaccharide galactosaminogalactan (fungal GAG) GH135 alpha-1,4-galactosaminogalactan hydrolase 3.2.1.- galactosaminogalactan exopolysaccharide galactosaminogalactan (fungal GAG) GH166 alpha-1,4-galactosaminogalactan hydrolase 3.2.1.- galactosaminogalactan GH191 poly-N-acetylgalactosamine endo-a-1,4-N-acetylgalactosaminidaseaDGalpNAc 3.2.1.- gellan gellan(polysaccharide) PL33 gellan lyase 4.2.2.25 gentiobiose GH3 gentiobiose b-1,6-glucosidase 3.2.1.- gentiobiose GH30 gentiobiose b-1,6-glucosidase 3.2.1.- glucosylglycerate glucosylglycerate GH13 Glucosylglycerate phosphorylase 2.4.1.352 glucosylglycerate glucosylglycerate GH13 [retaining] glucosylglycerol phosphorylase 2.4.1.359 glucosylglycerate glucosylglycerate GH63 glucosylglycerate hydrolase 3.2.1.208 glycoalkaloid strictosidine (monoterpene indole alkaloids) GH1 strictosidine beta-glucosidase 3.2.1.105 glycoalkaloid Raucaffricine (glucoalkaloid) GH1 raucaffricine beta-glucosidase 3.2.1.125 glycoalkaloid alpha-tomatine (glycoalkaloids) GH10 tomatinase 3.2.1.- glycoalkaloid GH2 glycyrrhizin b-glucuronidase 3.2.1.128 glycoalkaloid GH3 terpenoid b-1,2-glucosidase 3.2.1.- glycoalkaloid GH3 tomatin b-1,2-glucosidase 3.2.1.- glycoalkaloid GH3 hesperidin 6-O-a-rhamnosyl-b-glucosidase 3.2.1.168 glycolipid sulfoquinovoside (plant sulfolipid) GH188 sulfoquinovosidase 3.2.1.199 glycolipid sulfoquinovoside (plant sulfolipid) GH31 sulfoquinovosidase 3.2.1.199 glycolipid sterylglucoside (fungi) GH5 steryl beta-glucosidase 3.2.1.104 glycolipid glycosphingolipids GH5 endoglycoceramidase 3.2.1.123 glycolipid fungus-specific glucosylceramide (glycolipid) GH5 beta-glucosylceramidase 3.2.1.45 glycolipid glycosphingolipid, galactolipids GH5 beta-galactosylceramidase 3.2.1.46 glycolipid galactosylceramide, sphingolipids, galactolipids GH59 galactocerebrosidase 3.2.1.46 host glycan chondroitin sulfate CBM100 chondroitin sulfate binding associated with a PL29 in Polaribacter haliotis host glycan CBM105 chondroitin sulfate binding host glycan galactose, lactose, LacNAc CBM32 Binding to galactose and lactose has been demonstrated for the module of Micromonospora viridifaciens sialidase (PMID: 16239725). Binding to polygalacturonic acid has been shown for a Yersinia member (PMID: 17292916). Binding to LacNAc (beta-D-galactosyl-1,4-beta-D-N-acetylglucosamine) has been shown for an N-acetylglucosaminidase from Clostridium perfingens (PMID: 16990278). host glycan sialic acid CBM40 Modules of approx. 200 residues, found at the N-terminus of GH33 sialidases. Can also be found inserted in the beta-propeller of GH33 sialidases. The sialic acid binding function has been demonstrated for the N-terminal CBM40 of Vibrio cholerae sialidase (Moustafa et al. (2004) J Biol Chem 279:40819-26) (PMID: 15226294). host glycan fucose CBM47 Modules of approx 150 residues. Fucose-binding activity demonstrated host glycan galactose and to blood group A/B-antigens CBM51 Modules of approx. 150 residues found attached to various enzymes from families GH2, GH27, GH31, GH95, GH98 and GH101 . Binding to galactose and to blood group A/B-antigens demonstrated in the case of C. perfringens GH95CBM51 and GH98CBM51 respectively [Gregg KJ et al. (2008) J. Biol. Chem. 283:12604-13 PMID: 18292090]. host glycan glycosidases CBM57 Created from reading Schallus et al (2008) Mol Biol Cell. 19:3404-3414 [PMID: 18524852] and finding related domains attached to various glycosidases. host glycan hyaluronan CBM70 The hyaluronan-specific binding function of the N-terminal CBM70 module of Streptococcus pneumoniae hyaluronate lyase has been demonstrated. host glycan lactose and LacNAc CBM71 The two CBM71s of S. pneumoniae BgaA bind lactose and LacNAc. host glycan sialylated and non-sialylated glycans CBM93 Modules of approx. 160 residues with broad specificity glycan-binding properties, located at the N-terminus of GH33 sialidases. host glycan glycoprotein N-glycosylation CBM94 Modules of approx. 150 residues found at the C-terminus of the GT54 in eukaryotes. Involved in N-glycosylation by the binding of N-Acetylglucosamine host glycan N-acetylgalactosaminegalactan deacetylase CE18 N-acetylgalactosaminegalactan deacetylase 3.5.1.- host glycan host glycan CE20 Sialate O-acetylesterase 3.1.1.53 host glycan host glycan CE20 Acetylesterase 3.1.1.6 host glycan host glycan CE9 N-acetylglucosamine 6-phosphate deacetylase 3.5.1.25 host glycan host glycan CE9 N-acetylgalactosamine-6-phosphate deacetylase 3.5.1.- host glycan mucin GH101 endo-alpha-N-acetylgalactosaminidase 3.2.1.97 host glycan mucin-type O-glycans GH109 alpha-N-acetylgalactosaminidase 3.2.1.49 host glycan mucin-type O-glycans GH109 beta-N-acetylhexosaminidase 3.2.1.52 host glycan GH110 a-galactosidase 3.2.1.22 host glycan blood group B substances, host glycans GH110 alpha-1,3-galactosidase 3.2.1.- host glycan blood group B substances, host glycans GH110 antigen a-1,3-galactosidase 3.2.1.- host glycan keratan, host glycans GH111 keratan sulfate hydrolase (endo-beta-N-acetylglucosaminidase) 3.2.1.- host glycan lipid glucosylceramide (host cell surface) GH116 acid beta-glucosidase/beta-glucosylceramidase 3.2.1.45 host glycan glycosphingolipid (host glycan) GH123 glycosphingolipid beta-N-acetylgalactosaminidase 3.2.1.- host glycan GH123 exo-b-1,3-N-acetylgalactosaminidase 3.2.1.- host glycan GH123 exo-b-1,4-N-acetylgalactosaminidase 3.2.1.- host glycan GH123 b-N-acetyl-4-sulfo-galactosaminidase 3.2.1.- host glycan GH123 endo-b-1,4-N-acetylgalactosaminidase 3.2.1.- host glycan GH123 endo-b-1,3-N-acetylgalactosaminidase 3.2.1.- host glycan glycosphingolipid (host glycan) GH123 beta-N-acetylgalactosaminidase 3.2.1.53 host glycan GH127 hydroxyproline exo-b-1,2-arabinofunosidase 3.2.1.- host glycan mucin-type O-glycans GH129 alpha-N-acetylgalactosaminidase 3.2.1.49 host glycan sialic acid (O-glycan, N-glycan, mucin, host glycan) GH156 exo-alpha-sialidase 3.2.1.18 host glycan mucin-type O-glycans GH16 endo-beta-1,4-galactosidase 3.2.1.- host glycan GH16 mucin endo-b-1,4-galactosidase 3.2.1.- host glycan keratan sulfate (host glycan) GH16 keratan-sulfate endo-1,4-beta-galactosidase 3.2.1.103 host glycan hyaluronate (glycosaminoglycan of host glycan) GH16 hyaluronidase 3.2.1.35 host glycan N-glycan (host glycan) GH163 endo-beta-N-acetylglucosaminidase cleaving GlcNAc-beta-1,2-Man 3.2.1.- host glycan glycoproteins GH177 exo-alpha-sialidase 3.2.1.18 host glycan GH18 mannosyl-oligosaccharide exo-b-1,4-N-acetylglucosaminidase 3.2.1.- host glycan GH18 b-N-acetylhexosaminidase 3.2.1.52 host glycan N-glycan (host glycan) GH18 endo-beta-N-acetylglucosaminidase 3.2.1.96 host glycan mucin-type O-glycans GH181 exo-alpha-sialidase 3.2.1.18 host glycan N-glycan (host glycan) GH185 beta-N-acetyl-6-sulfo-glucosaminidase 3.2.1.- host glycan N-glycan (plant) GH2 mannosylglycoprotein endo-beta-mannosidase 3.2.1.152 host glycan mucin GH20 beta-6-SO3-N-acetylglucosaminidase 3.2.1.- host glycan N-glycan (host glycan, human milk oligosaccharides, chitin) GH20 beta-hexosaminidase 3.2.1.52 host glycan GH20 b-N-acetylgalactosaminidase 3.2.1.53 host glycan GH20 mannosyl-oligosaccharide endo-b-1,4-N-acetylglucosaminidase 3.2.1.96 host glycan human blood group A, mucin, host glycan GH27 alpha-N-acetylgalactosaminidase 3.2.1.49 host glycan GH29 a-1,3-L-galactosidase 3.2.1.- host glycan GH29 antigen exo-a-1,4-fucosidase 3.2.1.- host glycan GH29 a-L-glucosidase 3.2.1.- host glycan human milk oligosaccharides, mucin, host glycan GH29 alpha-1,3/1,4-L-fucosidase 3.2.1.111 host glycan GH29 antigen a-1,6-fucosidase 3.2.1.127 host glycan human milk oligosaccharides, mucin, host glycan GH29 alpha-L-fucosidase 3.2.1.51 host glycan human milk oligosaccharides, mucin, host glycan GH29 alpha-1,2-L-fucosidase 3.2.1.63 host glycan glycosphingolipid (host glycan) GH3 beta-glucosylceramidase 3.2.1.45 host glycan GH3 protein O endo-a-N-acetylgalactosaminidase 3.2.1.97 host glycan glucosylsphingosine, glucosylceramide (host glycans) GH30 glucosylceramidase 3.2.1.45 host glycan mannosyl-oligosaccharide GH31 mannosyl-oligosaccharide exo-a-1,3-glucosidase 3.2.1.207 host glycan human blood group A, mucin, host glycan GH31 alpha-N-acetylgalactosaminidase 3.2.1.217 host glycan sialic acid GH33 trans-sialidase 2.4.1.- host glycan pectin (rhamnogalacturonan II), lipopolysaccharides (bacteria) GH33 a-(2-keto)-(3-deoxy)-nononic acid hydrolase (KDNase) 3.2.1.- host glycan GH33 LPS exo-a-3-deoxy-2-octulosonidase (Kdo hydrolase) 3.2.1.124 host glycan sialic acid (O-glycan, N-glycan, mucin, host glycan) GH33 sialidase or neuraminidase 3.2.1.18 host glycan sialic acid (O-glycan, N-glycan, mucin, host glycan) GH33 anhydrosialidase 4.2.2.15 host glycan sialic acid (O-glycan, N-glycan, mucin, host glycan) GH34 sialidase or neuraminidase 3.2.1.18 host glycan galactan and arabinogalactan GH35 antigen exo-b-1,3-galactosidase 3.2.1.- host glycan GH36 antigen a-1,3-galactosidase 3.2.1.- host glycan GH36 antigen exo-a-1,3-galactosamine 3.2.1.- host glycan acetylgalactosamine (human blood group A and b, mucin glycoproteins) GH36 alpha-N-acetylgalactosaminidase 3.2.1.49 host glycan mannosyl-oligosaccharide GH38 mannosyl-oligosaccharide endo-a-1,P-mannosidase 3.2.1.- host glycan mannosyl-oligosaccharide GH38 mannosyl-oligosaccharide alpha-1,2-mannosidase 3.2.1.113 host glycan mannosyl-oligosaccharide GH38 mannosyl-oligosaccharide alpha-1,3-1,6-mannosidase 3.2.1.114 host glycan mannosyl-oligosaccharide GH38 mannosyl-oligosaccharide exo-a-1,6-mannosidase 3.2.1.163 host glycan mannosyl-oligosaccharide GH38 alpha-mannosidase 3.2.1.24 host glycan glycosaminoglycans heparan sulfate and dermatan sulfate (host glycan) GH39 alpha-L-iduronidase 3.2.1.76 host glycan GH42 antigen exo-b-1,3-galactosidase 3.2.1.- host glycan mannosyl-oligosaccharide GH47 alpha-mannosidase 3.2.1.113 host glycan glycosaminoglycan, hyaluronan, chondroitin sulfate, host glycan GH56 chondroitin hydrolase 3.2.1.- host glycan glycosaminoglycan, hyaluronan, chondroitin sulfate, host glycan GH56 hyaluronan endo-b-1,4-N-acetylglucosaminidase 3.2.1.35 host glycan sialic acid GH58 endo-N-acetylneuraminidase or endo-sialidase 3.2.1.129 host glycan mannosyl-oligosaccharide GH63 mannosyl-oligosaccharide exo-a-1,2-glucosidase 3.2.1.106 host glycan mannosyl-glycoprotein GH73 mannosyl-oligosaccharide endo-b-1,4-N-acetylglucosaminidase 3.2.1.96 host glycan heparan sulfate proteoglycans GH79 heparanase 3.2.1.166 host glycan heparan sulfate proteoglycans GH79 baicalin beta-glucuronidase 3.2.1.167 host glycan hyaluronan GH79 hyaluronoglucuronidase 3.2.1.36 host glycan paramyxovirus cleaves sialic acid of host glycans GH83 neuraminidase 3.2.1.18 host glycan cleave beta-O-linked GlcNAc of host glycan GH84 [protein]-3-O-(GlcNAc)-L-Ser/Thr beta-N-acetylglucosaminidase 3.2.1.169 host glycan hyaluronan GH84 hyaluronidase 3.2.1.35 host glycan mucin GH84 N-acetyl beta-glucosaminidase 3.2.1.52 host glycan mannosyl-oligosaccharide GH85 mannosyl-oligosaccharide endo-b-1,4-N-acetylglucosaminidase 3.2.1.96 host glycan sulfated glycosaminoglycans GH88 d-4,5-unsaturated beta-glucuronyl hydrolase 3.2.1.- host glycan GH88 gellan unsaturated-b-1,4-glucuronidase 3.2.1.179 host glycan sulfated glycosaminoglycans GH88 unsaturated chondroitin disaccharide hydrolase 3.2.1.180 host glycan alpha-Linked N-acetylglucosamine mucin GH89 alpha-N-acetylglucosaminidase 3.2.1.50 host glycan mannosyl-oligosaccharide GH92 mannosyl-oligosaccharide alpha-1,3-mannosidase 3.2.1.- host glycan mannosyl-oligosaccharide GH92 mannosyl-oligosaccharide exo-a-1,4-mannosidase 3.2.1.- host glycan mannosyl-oligosaccharide GH92 mannosyl-oligosaccharide endo-a-1,P-mannosidase 3.2.1.- host glycan host N-glycan GH92 alpha-1,2-mannosidase 3.2.1.- host glycan host N-glycan GH92 alpha-1,3-mannosidase 3.2.1.- host glycan mannosyl-oligosaccharide GH92 mannosyl-oligosaccharide alpha-1,2-mannosidase 3.2.1.113 host glycan mannosyl-oligosaccharide GH92 alpha-mannosidase 3.2.1.24 host glycan alpha-L-fucoside GH95 alpha-L-fucosidase 3.2.1.51 host glycan blood group A and B substances, host glycans GH98 blood-group endo-beta-1,4-galactosidase 3.2.1.102 host glycan host N-glycan GH99 mannosyl-oligosaccharide endo-a-1,2-mannosidase 3.2.1.130 host glycan N-glycans GH99 N-glycan endo-a-1,2-mannosidase 3.2.1.198 host glycan host glycan GT138 UDP-bLRhap: Thr-Rhamnosyl transferase (avirulence protein avrB) 2.4.1.- host glycan Heparin and heparan sulfate(host glycan) PL12 heparin lyase / heparin lyase I 4.2.2.7 host glycan heparin sulfate(host glycan) PL12 heparin-sulfate lyase 4.2.2.8 host glycan heparin and heparan sulfate(host glycan) PL13 heparin lyase 4.2.2.7 host glycan PL15 exo-heparin lyase (reducing-end specific) 4.2.2.- host glycan hyaluronan PL16 hyaluronan lyase 4.2.2.1 host glycan PL17 hyaluronate lyase 4.2.2.1 host glycan PL21 acharan-sulfate lyase 4.2.2.- host glycan Heparin and heparan sulfate(host glycan) PL21 heparin lyase 4.2.2.7 host glycan heparin sulfate(host glycan) PL21 heparin-sulfate lyase 4.2.2.8 host glycan PL23 chondroitin lyase/chondroitinase 4.2.2.- host glycan PL29 hyaluronate lyase 4.2.2.1 host glycan PL29 chondroitin B lyase 4.2.2.19 host glycan PL29 chondroitin AC lyase 4.2.2.5 host glycan hyaluronate(host glycan) PL30 hyaluronate lyase 4.2.2.1 host glycan hyaluronate(host glycan) PL33 hyaluronate lyase 4.2.2.1 host glycan glycosaminoglycans(host glycan) PL33 chondroitin sulfate lyase 4.2.2.20 host glycan PL35 chondroitin lyase/chondroitinase 4.2.2.- host glycan PL35 hyaluronate lyase 4.2.2.1 host glycan PL35 heparin-sulfate lyase 4.2.2.8 host glycan PL37 chondroitin AC lyase 4.2.2.5 host glycan heparin sulfate(host glycan) PL37 heparin-sulfate lyase / heparin lyase III 4.2.2.8 host glycan dermatan sulfate(host glycan) PL6 chondroitinase B 4.2.2.19 host glycan PL8 exo-hyaluronate lyase 4.2.2.- host glycan hyaluronan PL8 hyaluronate lyase 4.2.2.1 host glycan PL8 chondroitin B lyase 4.2.2.19 host glycan glycosaminoglycans(host glycan) PL8 chondroitin AC lyase 4.2.2.5 host glycan Heparin and heparan sulfate(host glycan) PL8 heparin lyase / heparin lyase I 4.2.2.7 human milk oligosaccharides;host glycans GH112 b-1,3-galactosyl-N-acetyl-glucosamine phosphorylase 2.4.1.211 human milk oligosaccharides;host glycans human milk oligosaccharides, host glycans GH112 b-1,3-galactosyl-N-acetyl-galactosamine phosphorylase 2.4.1.211 human milk oligosaccharides;host glycans human milk oligosaccharides, host glycans GH112 D-galactosyl-beta-1,4-L-rhamnose phosphorylase 2.4.1.247 human milk polysaccharide lactose in milk, phlorizin (polyphenols) in fruit GH1 lactase 3.2.1.108 human milk polysaccharide human milk oligosaccharides GH136 Lacto-N-biosidase (Lewis antigen a/b specificity) 3.2.1.- human milk polysaccharide human milk oligosaccharides GH136 lacto-N-biosidase 3.2.1.140 human milk polysaccharide fucosylated human milk oligosaccharides GH151 alpha-L-fucosidase 3.2.1.51 human milk polysaccharide lacto-N-tetraose (human milk oligosaccharides) GH20 lacto-N-biosidase 3.2.1.140 lactose GH2 lactose b-1,4-galactosidase 3.2.1.108 lactose GH50 b-galactosidase 3.2.1.23 lignin lignin AA1 dihydrogeodin oxidase 1.10.3.- lignin lignin AA1 Laccase / p-diphenol:oxygen oxidoreductase / ferroxidase 1.10.3.2 lignin lignin AA2 peroxidase 1.11.1.- lignin lignin AA2 ascorbate peroxidase 1.11.1.11 lignin lignin AA2 manganese peroxidase 1.11.1.13 lignin lignin AA2 lignin peroxidase 1.11.1.14 lignin lignin AA2 versatile peroxidase 1.11.1.16 lignin lignin AA2 cytochrome-c peroxidase 1.11.1.5 lignin lignin AA3 pyranose oxidase 1.1.3.10 lignin lignin AA3 alcohol oxidase 1.1.3.13 lignin AA3 Ecdysone oxidase 1.1.3.16 lignin lignin AA3 glucose 1-oxidase 1.1.3.4 lignin lignin AA3 aryl alcohol oxidase 1.1.3.7 lignin AA3 Oligosaccharide dehydrogenase (FAD) 1.1.5.- lignin AA3 Glucose 1-dehydrogenase (FAD, quinone) 1.1.5.9 lignin AA3 Pyranose dehydrogenase 1.1.99.29 lignin lignin AA4 vanillyl-alcohol oxidase 1.1.3.38 lignin lignin AA5 raffinose oxidase 1.1.3.- lignin lignin AA5 alcohol oxidase 1.1.3.13 lignin lignin AA5 5-(hydroxymethyl)furfural oxidase 1.1.3.47 lignin AA5 Aryl alcohol oxidase 1.1.3.7 lignin lignin AA5 galactose oxidase 1.1.3.9 lignin lignin AA5 glyoxal oxidase 1.2.3.15 lignin lignin AA6 1,4-benzoquinone reductase 1.6.5.6 lignin lignin AA8 Iron reductase domain NA lignin lignin CE15 4-O-methyl-glucuronoyl methylesterase 3.1.1.117 mannosylglycerate mannosylglycerate GH63 mannosylglycerate alpha-mannosidase / mannosylglycerate hydrolase 3.2.1.170 pectin pectin AA17 Lytic polygalacturonic acid monooxygenase (C4-hydroxylating) 1.14.99.- pectin various CBM77 Pectin binding modules of approx. 110 residues. The Ruminococcus flavefaciens CBM77 was shown to bind various pectins of low degree of esterification. pectin rhamnogalacturonan-I CBM95 N-terminal modules of galactan synthases involved in pectic galactan side-chain addition pectin polygalacturonic acid CBM97 Modules found in Bacteroidota, in the multimodular b-L-arabinofuranosidase/b-glucuronidase/CBM57 proteins involved in RGII breakdown pectin pectin CE12 pectin acetylesterase 3.1.1.- pectin pectin CE12 rhamnogalacturonan acetylesterase 3.1.1.86 pectin pectin CE13 pectin acetylesterase 3.1.1.- pectin pectin CE19 Pectin methylesterase 3.1.1.11 pectin pectin CE8 pectin methylesterase 3.1.1.11 pectin pectin GH105 d-4,5-unsaturated alpha-galacturonidase 3.2.1.- pectin pectin (rhamnogalacturonan I) GH105 unsaturated rhamnogalacturonyl hydrolase 3.2.1.172 pectin pectin (rhamnogalacturonan I) GH106 rhamnogalacturonan alpha-L-rhamnohydrolase 3.2.1.174 pectin pectin (rhamnogalacturonan II) GH106 alpha-L-rhamnosidase 3.2.1.40 pectin pectin (rhamnogalacturonan II) GH127 rhamnogalacturonan II endo-a-1,3-aceric acid hydrolase 3.2.1.- pectin pectin (rhamnogalacturonan II) GH137 beta-L-arabinofuranosidase 3.2.1.185 pectin pectin (rhamnogalacturonan II) GH138 rhamnogalacturonan alpha-1,2-galacturonohydrolase 3.2.1.173 pectin pectin (rhamnogalacturonan II) GH139 alpha-2-O-Me-L-fucosidase 3.2.1.- pectin pectin (rhamnogalacturonan II) GH140 beta-1,2-apiosidase 3.2.1.- pectin pectin (rhamnogalacturonan II) GH141 alpha-L-fucosidase 3.2.1.51 pectin pectin (rhamnogalacturonan II) GH142 beta-L-arabinofuranosidase 3.2.1.185 pectin pectin (rhamnogalacturonan II) GH143 2-keto-3-deoxy-D-lyxo-heptulosaric acid hydrolase 3.2.1.- pectin beta-galactoside (pectin) GH173 beta--galactosidase (EC 3.2.1.23) 3.2.1.23 pectin pectin (rhamnogalacturonan II) GH2 alpha-L-arabinopyranosidase 3.2.1.- pectin pectin (rhamnogalacturonan II) GH2 beta-galacturonidase 3.2.1.- pectin GH2 rhamnogalacturonan II exo-b-1,3-galacturonidase 3.2.1.- pectin xylogalacturonan (pectin) GH28 xylogalacturonan hydrolase 3.2.1.- pectin galacturonan (pectin) GH28 polygalacturonase 3.2.1.15 pectin rhamnogalacturonan (pectin) GH28 rhamnogalacturonase 3.2.1.171 pectin pectin (rhamnogalacturonan I) GH28 rhamnogalacturonan alpha-1,2-galacturonohydrolase 3.2.1.173 pectin galacturonan (pectin) GH28 exo-polygalacturonase 3.2.1.67 pectin GH28 galacturonan exo-a-1,4-galacturonidase 3.2.1.67 pectin galacturonan (pectin) GH28 exo-polygalacturonosidase 3.2.1.82 pectin GH28 galacturonan exo-a-1,4-galacturobiodase 3.2.1.82 pectin galacturonides (polygalacturonan of pectin) GH4 alpha-galacturonase 3.2.1.67 pectin rhamnogalacturonan GH78 rhamnogalacturonan alpha-L-rhamnohydrolase 3.2.1.174 pectin pectin PL1 pectin lyase 4.2.2.10 pectin pectin PL1 pectate lyase 4.2.2.2 pectin homogalacturonan(de-esterified pectin) PL1 exo-pectate lyase 4.2.2.9 pectin pectin PL10 pectate lyase 4.2.2.2 pectin rhamnogalacturonan I(pectin from the plant cell wall) PL11 rhamnogalacturonan endolyase 4.2.2.23 pectin rhamnogalacturonan I(pectin from the plant cell wall) PL11 rhamnogalacturonan exolyase 4.2.2.24 pectin pectin PL2 pectate lyase 4.2.2.2 pectin homogalacturonan(de-esterified pectin) PL2 exo-polygalacturonate lyase 4.2.2.9 pectin pectin( D-galacturonate) PL22 oligogalacturonate lyase / oligogalacturonide lyase 4.2.2.6 pectin PL22 exo-unsaturated disaccharide pectate lyase 4.2.2.9 pectin rhamnogalacturonan I(pectin from the plant cell wall) PL26 rhamnogalacturonan exolyase 4.2.2.24 pectin PL27 L-rhamnose-a-1,4-D-glucuronate lyase 4.2.2.28 pectin pectate PL3 pectate lyase 4.2.2.2 pectin rhamnogalacturonan I(pectin from the plant cell wall) PL4 rhamnogalacturonan endolyase 4.2.2.23 pectin PL9 pectin lyase 4.2.2.10 pectin pectate PL9 pectate lyase 4.2.2.2 pectin rhamnogalacturonan I(pectin from the plant cell wall) PL9 rhamnogalacturonan endolyase 4.2.2.23 pectin homogalacturonan(de-esterified pectin) PL9 exopolygalacturonate lyase 4.2.2.9 peptidoglycan peptidoglycan CE4 LPS deacetylase 3.5.1.- peptidoglycan peptidoglycan CE4 Poly-beta-1,6-N-acetylglucosamine deacetylase 3.5.1.- peptidoglycan CE4 Peptidoglycan N-acetylglucosamine deacetylase 3.5.1.104 peptidoglycan peptidoglycan GH102 peptidoglycan lytic transglycosylase 4.2.2.29 peptidoglycan peptidoglycan GH103 peptidoglycan lytic transglycosylase 4.2.2.29 peptidoglycan peptidoglycan GH104 peptidoglycan lytic transglycosylase 4.2.2.29 peptidoglycan peptidoglycan GH108 N-acetylmuramidase 3.2.1.17 peptidoglycan peptidoglycan GH170 6-phospho-N-acetylmuramidase 3.2.1.- peptidoglycan peptidoglycan GH171 peptidoglycan beta-N-acetylmuramidase 3.2.1.92 peptidoglycan peptidoglycan GH18 peptidoglycan hydrolase with endo-beta-N-acetylglucosaminidase specificity 3.2.1.- peptidoglycan peptidoglycan GH184 peptidoglycan beta-N-acetylmuramidase 3.2.1.17 peptidoglycan peptidoglycan GH19 lysozyme 3.2.1.17 peptidoglycan GH190 peptidoglycan lytic b-1,4-muraminidase 4.2.2.29 peptidoglycan peptidoglycan GH22 lysozyme type i 3.2.1.17 peptidoglycan peptidoglycan GH22 lysozyme type C 3.2.1.17 peptidoglycan peptidoglycan GH23 lysozyme type G 3.2.1.17 peptidoglycan peptidoglycan GH23 peptidoglycan lyase ( also known in the literature as peptidoglycan lytic transglycosylase) 4.2.2.29 peptidoglycan peptidoglycan GH24 lysozyme 3.2.1.17 peptidoglycan peptidoglycan GH25 lysozyme 3.2.1.17 peptidoglycan peptidoglycan GH3 beta-N-acetylglucosaminide phosphorylases 2.4.1.- peptidoglycan peptidoglycan GH73 peptidoglycan hydrolase with endo-beta-N-acetylglucosaminidase specificity 3.2.1.- peptidoglycan peptidoglycan GT119 peptidoglycan glycosyltransferase 2.4.1.129 peptidoglycan PL9 thiopeptidoglycan lyase 4.2.2.- plant glycoside amygdalin (cyanogenic glycosides) GH1 amygdalin beta-glucosidase 3.2.1.117 plant glycoside prunasin (cyanogenic glycosides) GH1 prunasin beta-glucosidase 3.2.1.118 plant glycoside vicianin (cyanogenic glycosides) GH1 vicianin hydrolase 3.2.1.119 plant glycoside glucosinolates (sulfur-containing phytochemicals) GH1 thioglucosidase 3.2.1.147 plant glycoside Glc-conjugated ABA (plant) GH1 ABA-specific beta-glucosidase 3.2.1.175 plant glycoside DIMBOA glucoside (polyphenol) GH1 DIMBOA beta-glucosidase 3.2.1.182 plant glycoside Glc-conjugated ABA (plant) GH17 ABA-specific beta-glucosidase 3.2.1.175 plant glycoside protodioscin (plant steroidal saponin) GH3 protodioscin 26-O-beta--D-glucosidase 3.2.1.186 plant glycoside glycyrrhizin GH79 glycyrrhizin b-glucuronidase 3.2.1.128 polyphenol pyrroloquinoline quinone (PQQ, polyphenol) AA12 Oxidoreductases 1.-.-.- polyphenol Hydroxycinnamic acids(Phenolic acids) CE1 Carboxylic ester hydrolase 3.1.1.- polyphenol cutin CE5 cutinase 3.1.1.74 polyphenol isoflavone GH1 isoflavone 7-O-glucosyl b-glucosidase 3.2.1.- polyphenol rutin GH1 rutin b-(rhamnosyl)-glucosidase 3.2.1.- polyphenol beta-primeverosides (tea plant phytochemicals) GH1 beta-primeverosidase 3.2.1.149 polyphenol Daidzin and genistin, Furcatin (polyphenol) GH1 isoflavonoid 7-O-beta-apiosyl-beta-glucosidase 3.2.1.161 polyphenol Furostanol (polyphenol) GH1 protodioscin 26-O-beta--D-glucosidase 3.2.1.186 polyphenol coniferin (glucoside of coniferyl alcohol) GH3 coniferin beta-glucosidase 3.2.1.126 polyphenol GH30 baicalin b-glucuronidase 3.2.1.167 polyphenol rutin (polyphenol) GH5 beta-rutinosidase /alpha-L-rhamnose-(1,6)-beta-D-glucosidase 3.2.1.- polyphenol hesperidin GH5 hesperidin 6-O-a-rhamnosyl-b-glucosidase 3.2.1.168 polyphenol naringenin (flavonoid) and tea aroma GH5 beta-glucosidase 3.2.1.21 polyphenol hesperidin GH55 hesperidin 6-O-a-rhamnosyl-b-glucosidase 3.2.1.168 polyphenol GH78 isoflavone 7-O-glucosyl a-1,6-rhamnosidase 3.2.1.- porphyran porphyran (red algal beta-galactose-sulfate) GH16 [retaining] beta-porphyranase 3.2.1.178 raffinose raffinose/stachyose oligosaccharides (plant seeds) GH36 stachyose synthase 2.4.1.67 raffinose raffinose oligosaccharides GH36 raffinose synthase 2.4.1.82 raffinose alpha-galactoside (raffinose family of oligosaccharides) GH4 alpha-galactosidase 3.2.1.22 rhamnose L-rhamnose CBM67 Fujimoto et al. [PMID : 23486481] disclosed the L-rhamnose binding activity and 3-D structure of the CBM67 of Streptomyces avermitilis alpha-L-rhamnosidase (SaRha78A) solabiose GH94 solabiose phosphorylase 2.4.1.389 sucrose sucrose GH100 sucrose b-2,1-fructosidase 3.2.1.26 sucrose sucrose GH13 [retaining] sucrose 6(F)-phosphate phosphorylase 2.4.1.329 sucrose Sucrose GH13 amylosucrase 2.4.1.4 sucrose Sucrose GH13 sucrose phosphorylase 2.4.1.7 sucrose sucrose GH13 [retaining] sucrose alpha-glucosidase 3.2.1.48 sucrose sucrose GH13 isomaltulose synthase 5.4.99.11 sucrose sucrose GH31 sucrase-isomaltase 3.2.1.48 sucrose sucrose and its isomeric disaccharides GH4 maltose-6-phosphate glucosidase 3.2.1.122 trehalose trehalose CE1 Trehalose 6-O-mycolyltransferase 2.3.1.122 trehalose GH13 trehalose a-1,1-glucosidase 3.2.1.28 trehalose trehalose GH13 trehalose-6-phosphate hydrolase 3.2.1.93 trehalose trehalose GH15 alpha,alpha-trehalase 3.2.1.28 trehalose alpha-trehalose GH37 alpha,alpha-trehalase 3.2.1.28 triglyceride CE5 Triacylglycerol lipase 3.1.1.3 ulvan ulvan CBM90 Modules of approx 110 residues appended to PL24 and PL28 ulvan lyases; ulvan-binding function demonstrated for the CBM90 module of PL28 ulvan lyase from Nonlabens ulvanivorans ulvan ulvan GH105 d-4,5-unsaturated beta-glucuronyl hydrolase 3.2.1.- ulvan GH39 ulvan endo-a-1,3-(3-sulfo)-rhamnosidase 3.2.1.- ulvan PL24 b-D-glucuronate ulvan lyase 4.2.2.- ulvan PL24 a-L-iduronate ulvan lyase 4.2.2.- ulvan PL25 b-D-glucuronate ulvan lyase 4.2.2.- ulvan PL25 a-L-iduronate ulvan lyase 4.2.2.- ulvan PL28 b-D-glucuronate ulvan lyase 4.2.2.- ulvan PL28 a-L-iduronate ulvan lyase 4.2.2.- ulvan PL37 b-D-glucuronate ulvan lyase 4.2.2.- ulvan PL37 a-L-iduronate ulvan lyase 4.2.2.- xanthan xanthan CBM84 Modules of approx. 140 aminoacids appended to enzymes of different families of CAZymes. A xanthan-binding function was reported for the GH9 xanthanase of Paenibacillus nanensis by Moroz et al. ACS Catal., 2018, 8 (7), pp 6021-6034. xanthan xanthan PL8 xanthan lyase 4.2.2.12 xylan xylan AA10 lytic xylan monooxygenase / xylan oxidase (glycosidic bond-cleaving) 1.14.99.- xylan xylan AA14 lytic xylan monooxygenase / xylan oxidase (C1-hydroxylating) 1.14.99.- xylan AA7 xylooligosaccharide oxidase 1.1.3.- xylan AA9 lytic xylan monooxygenase / xylan oxidase (C4-hydroxylating) 1.14.99.- xylan xylan and xylooligosaccharide CBM15 Binding to xylan and xylooligosaccharides has been demonstrated in the case of Xyn10C of Cellvibrio mixtus. xylan beta-1,3-xylan CBM31 Binding to beta-1,3-xylan has been demonstrated for the C-terminal module of the beta-1,3-xylanase of Alcaligenes sp. XY234. xylan xylan and xylooligosaccharide CBM36 Modules of approx. 120-130 residues displaying structural similarities to CBM6 modules. The only CBM36 currently characterised, that from Paenbacillus polymyxa xylanase 43A, shows calcium-dependent binding of xylans and xylooligosaccharides. X-ray crystallography shows that there is a direct interaction between calcium and ligand. xylan arabinoxylan CBM42 Modules of approx. 160 residues found mostly at the C-terminus of GH54 catalytic domains. Binding to arabinofuranose (present in arabinoxylan) has been demonstrated. xylan xylan CBM60 Modules of approx 120 residues usually found appended to xylanases. The xylan-binding function and the relatedness (circular permutation) to family CBM36 has been demonstrated [PMID: 20659893]. xylan xylan CBM86 Created after the report of an activity [Leth et al. (2018), Nat. Microbiol, PMID:29610517] and a structure [Leth et al. (2019), FEBS J, PMID:31693302] of a xylan-binding module in the Xyn10A protein of Roseburia intestinalis L1-82. xylan xylan CBM89 beechwood xylan and rye arabinoxylan binding xylan xylan CBM91 Binding to xylans (birchwood and oat spelt) xylan Acyl-CoA,Palmitoyl-CoA and other long-chain acyl-CoAs(ester) CE1 diacylglycerol O-acyltransferase 2.3.1.20 xylan xylan CE1 Acetylxylan esterase 3.1.1.72 xylan Feruloyl-polysaccharide(esterified sugar) CE1 Feruloyl esterase 3.1.1.73 xylan acetyl xylan CE12 Carboxylic ester hydrolase 3.1.1.- xylan acetyl xylan CE12 acetyl xylan esterase 3.1.1.72 xylan various carbohydrate acetyl ester CE16 acetylesterase (active on various carbohydrate acetylesters) 3.1.1.6 xylan acetylxylan CE2 6-O-glycoside deacetylase 3.1.1.- xylan acetylxylan CE2 Acetylesterase 3.1.1.6 xylan acetylxylan CE2 acetyl xylan esterase 3.1.1.72 xylan xyloglucan CE3 Acetylesterase 3.1.1.6 xylan acetylxylan CE3 acetyl xylan esterase 3.1.1.72 xylan CE4 Acetylesterase 3.1.1.6 xylan acetylxylan CE4 acetyl xylan esterase 3.1.1.72 xylan acetylxylan CE5 acetyl xylan esterase 3.1.1.72 xylan acetylxylan CE6 acetyl xylan esterase 3.1.1.72 xylan acetylxylan CE7 Carboxylic ester hydrolase 3.1.1.- xylan acetylxylan CE7 acetyl xylan esterase 3.1.1.72 xylan beta-glucoside, beta-xyloside GH1 beta-xylosidase 3.2.1.37 xylan xylan GH10 xylan endotransglycosylase 2.4.2.- xylan arabinoxylan GH10 [retaining] arabinoxylan-specific endo-beta-1,4-xylanase 3.2.1.- xylan GH10 MLX exo-b-1,4-xylosidase 3.2.1.- xylan GH10 reducing end xylan exo-b-1,4-xylosidase 3.2.1.156 xylan xylan GH10 endo-1,3-beta-xylanase 3.2.1.32 xylan GH10 xylan exo-b-1,4-xylosidase 3.2.1.37 xylan xylan GH10 endo-1,4-beta-xylanase 3.2.1.8 xylan xylan GH11 exo-1,4-beta-xylosidase 3.2.1.37 xylan xylan GH11 endo-beta-1,4-xylanase 3.2.1.8 xylan glucuronoxylan GH115 xylan alpha-1,2-glucuronidase 3.2.1.131 xylan xylan GH120 beta-xylosidase 3.2.1.37 xylan xylan GH141 xylanase 3.2.1.8 xylan GH159 a-L-arabinofuranosidase 3.2.1.55 xylan beta-xyloside GH2 beta-xylosidase 3.2.1.37 xylan xylan GH26 MLX exo-b-1,4-xylosidase 3.2.1.- xylan beta(1,3)-xylan (algae) GH26 beta-1,3-xylanase 3.2.1.32 xylan xylan GH3 xylan 1,4-beta-xylosidase 3.2.1.37 xylan GH3 xylan exo-b-1,3-xylosidase 3.2.1.72 xylan GH3 xylan endo-b-1,4-xylosidase 3.2.1.8 xylan xylan GH30 [reducing end] beta-xylosidase 3.2.1.- xylan GH30 glucuronoxylan endo-b-1,4-xylosidase 3.2.1.- xylan GH30 glucuronoxylan exo-b-1,4-xylobiosidase 3.2.1.- xylan xylan GH30 glucuronoarabinoxylan endo-beta-1,4-xylanase 3.2.1.136 xylan GH30 reducing end xylan exo-b-1,4-xylosidase 3.2.1.156 xylan xylan GH30 beta-xylosidase 3.2.1.37 xylan xylan GH30 endo-beta-1,4-xylanase 3.2.1.8 xylan xylan GH39 beta-xylosidase 3.2.1.37 xylan alpha-glucuronide in glucuronoxylan GH4 alpha-glucuronidase 3.2.1.139 xylan xylan GH43 beta-xylosidase 3.2.1.37 xylan arabinoxylan GH43 alpha-L-arabinofuranosidase 3.2.1.55 xylan beta-1,3-xylan (algae) GH43 xylan exo-b-1,3-xylosidase 3.2.1.72 xylan xylan GH43 xylanase 3.2.1.8 xylan GH44 xylan endo-b-1,4-xylosidase 3.2.1.8 xylan arabinoxylans GH5 arabinoxylan-specific endo-beta-1,4-xylanase 3.2.1.- xylan GH5 xylan exo-b-1,4-xylosidase 3.2.1.37 xylan xylan GH5 endo-beta-1,4-xylanase 3.2.1.8 xylan GH51 arabinoxylan exo-a-1,3-L-arabinofuranosidase 3.2.1.- xylan arabinan GH51 beta-xylosidase 3.2.1.37 xylan xylan GH51 endo-beta-1,4-xylanase 3.2.1.8 xylan xylan GH52 beta-xylosidase 3.2.1.37 xylan arabinan, arabinoxylan GH54 beta-xylosidase 3.2.1.37 xylan GH6 xylan endo-b-1,4-xylosidase 3.2.1.8 xylan GH62 xylan endo-b-1,4-xylosidase 3.2.1.8 xylan xylan side chain GH67 xylan alpha-1,2-glucuronidase 3.2.1.131 xylan xylan side chain GH67 alpha-glucuronidase 3.2.1.139 xylan xylan GH8 reducing-end-xylose releasing exo-oligoxylanase 3.2.1.156 xylan GH8 xylan endo-b-1,3-xylosidase 3.2.1.32 xylan xylan GH8 endo-1,4-beta-xylanase 3.2.1.8 xylan GH9 xylan endo-b-1,4-xylosidase 3.2.1.8 xylan xylan GH98 endo-beta-1,4-xylanase 3.2.1.8 xylan;beta-glucan xylan,1,3/beta-1,4-glucans CBM22 A xylan binding function has been demonstrated in several cases and affinity with mixed beta-1,3/beta-1,4-glucans in one. In several cases a thermostabilizing effect has also been seen. xylan;beta-glucan xylan, beta-1,3-glucan, beta-1,3-1,4-glucan, beta-1,6-glucan and amorphous cellulose CBM4 Modules of approx. 150 residues found in bacterial enzymes. Binding of these modules has been demonstrated with xylan, beta-1,3-glucan, beta-1,3-1,4-glucan, beta-1,6-glucan and amorphous cellulose but not with crystalline cellulose. xylan;beta-glucan;chitin xylan, yeast cell wall glucan and chitin CBM54 Binding to xylan, yeast cell wall glucan and chitin shown in Dvortsov et al., Microbiology UK (2009) in press. xylan;beta-mannan;beta-galactan xylan,decorated soluble mannan and mannooligosaccharide,beta-galactan CBM35 Modules of approx. 130 residues. A module that is conserved in three Cellvibrio xylan-degrading enzymes binds to xylan and the interaction is calcium dependent, while a module from a Cellvibrio mannanase binds to decorated soluble mannans and mannooligosaccharides. A module in a Phanerochaete chrysosporium galactan 1,3-beta-galactosidase binds to beta-galactan. xylan;chitin;cellulose xylan, chitin, microcrystalline and phosphoric-acid swollen cellulose, as well as more heterogeneous substrates, such as alfalfa cell walls, banana stem and wheat straw. CBM37 Modules of approx. 100 residues, conserved in numerous R. albus polysaccharide-degrading enzymes and other proteins from this bacterium. Several members of CBM37 have been shown to exhibit rather broad binding specificity to xylan, chitin, microcrystalline and phosphoric-acid swollen cellulose, as well as more heterogeneous substrates, such as alfalfa cell walls, banana stem and wheat straw. xylan;host glycan plant lectin, xylan CBM13 Modules of approx. 150 residues which always appear as a threefold internal repeat. The only apparent exception to this, xylanase II of Actinomadura sp. FC7 (GenBank U08894), is in fact not completely sequenced. These modules were first identified in several plant lectins such as ricin or agglutinin of Ricinus communis which bind galactose residues. The three-dimensional structure of a plant lectin has been determined and displays a pseudo-threefold symmetry in accord with the observed sequence threefold repeat. These modules have since been found in a number of other proteins of various functions including glycoside hydrolases and glycosyltransferases. While in the plant lectins this module binds mannose, binding to xylan has been demonstrated in the Streptomyces lividans xylanase A and arabinofuranosidase B. Binding to GalNAc has been shown for the corresponding module of GalNAc transferase 4. For the other proteins, the binding specificity of these modules has not been established. The pseudo three-fold symmetry of the CBM13 module has now been confirmed in the 3-D structure of the intact, two-domain, xylanase of Streptomyces olivaceoviridis. xyloglucan xyloglucan CBM65 CBM65A and CBM65B, derived from Eubacterium cellulosolvens endoglucanase EcCel5A, bind to a range of beta-glucans but, uniquely, display significant preference for xyloglucan xyloglucan xyloglucan CBM75 Modules of 290 residues appended to GH43_16 enzymes. So far found exclusively in Ruminococci. The xyloglucan-binding function was demonstrated for the R. flavefaciens protein. xyloglucan xyloglucan GH12 xyloglucan hydrolase 3.2.1.151 xyloglucan xyloglucan (plant) GH16 xyloglucan:xyloglucosyltransferase 2.4.1.207 xyloglucan xyloglucan GH16 xyloglucanase 3.2.1.151 xyloglucan GH26 xyloglucan endo-b-1,4-glucosidase 3.2.1.151 xyloglucan GH3 xyloglucan exo-b-1,4-glucosidase 3.2.1.- xyloglucan xyloglucan (plant) GH3 isoprimeverose-producing oligoxyloglucan hydrolase 3.2.1.120 xyloglucan xyloglucan (plant) GH31 alpha-xylosidase 3.2.1.177 xyloglucan xyloglucan GH44 xyloglucanase 3.2.1.151 xyloglucan xyloglucan GH45 xyloglucan-specific endo-beta-1,4-glucanase / endo-xyloglucanase 3.2.1.151 xyloglucan GH45 xyloglucan endo-b-1,4-glucosidase 3.2.1.151 xyloglucan GH5 reducing end xyloglucan exo-b-1,4-glucobiosidase 3.2.1.150 xyloglucan xyloglucan GH5 xyloglucan-specific endo-beta-1,4-glucanase 3.2.1.151 xyloglucan oligoxyloglucan GH74 oligoxyloglucan reducing end-specific cellobiohydrolase 3.2.1.150 xyloglucan xyloglucan GH74 xyloglucanase 3.2.1.151 xyloglucan;arabinogalactan;beta-mannan xyloglucan, arabinogalactan and galactomannan CBM62 The CBM62 module of Clostridium thermocellum Cthe_2193 protein binds galactose moieties found on xyloglucan, arabinogalactan and galactomannan. xyloglucan;beta-mannan;beta-glucan xyloglucan, glucomannan, and barley beta-glucan CBM76 Modules of approx. 170 residues appended to GH44 enzymes. So far found exclusively in Ruminococci. Broad specificity binding to beta-glucans demontsrated for the R. flavefaciens module, which binds xyloglucan, glucomannan, and barley beta-glucan.