LOCUS NC_006347 20243 bp DNA linear CON 04-APR-2020 DEFINITION Bacteroides fragilis YCH46, complete genome. ACCESSION NC_006347 VERSION NC_006347.1 DBLINK BioProject: PRJNA224116 BioSample: SAMD00061068 Assembly: GCF_000009925.1 KEYWORDS RefSeq. SOURCE Bacteroides fragilis YCH46 ORGANISM Bacteroides fragilis YCH46 Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides. REFERENCE 1 AUTHORS Kuwahara,T., Yamashita,A., Hirakawa,H., Nakayama,H., Toh,H., Okada,N., Kuhara,S., Hattori,M., Hayashi,T. and Ohnishi,Y. TITLE Genomic analysis of Bacteroides fragilis reveals extensive DNA inversions regulating cell surface adaptation JOURNAL Proc. Natl. Acad. Sci. U.S.A. 101 (41), 14919-14924 (2004) PUBMED 15466707 REFERENCE 2 (bases 1 to 20243) AUTHORS Hattori,M., Yamashita,A., Toh,H., Oshima,K. and Shiba,T. TITLE Direct Submission JOURNAL Submitted (20-APR-2004) Contact:Masahira Hattori Graduate School of Frontier Sciences, University of Tokyo; 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8561, Japan COMMENT ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Date :: 04/04/2020 09:42:13 Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Method :: Best-placed reference protein Annotation Software revision :: 4.11 Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA; Genes (total) :: 4,454 CDSs (total) :: 4,360 Genes (coding) :: 4,278 CDSs (with protein) :: 4,278 Genes (RNA) :: 94 rRNAs :: 6, 6, 6 (5S, 16S, 23S) complete rRNAs :: 6, 6, 6 (5S, 16S, 23S) tRNAs :: 74 ncRNAs :: 2 Pseudo Genes (total) :: 82 CDSs (without protein) :: 82 Pseudo Genes (ambiguous residues) :: 0 of 82 Pseudo Genes (frameshifted) :: 42 of 82 Pseudo Genes (incomplete) :: 34 of 82 Pseudo Genes (internal stop) :: 28 of 82 Pseudo Genes (multiple problems) :: 17 of 82 CRISPR Arrays :: 1 ##Genome-Annotation-Data-END## REFSEQ INFORMATION: The reference sequence was derived from AP006841. This work was done in collaboration with Tomomi Kuwahara, Haruyuki Nakayama, Natsumi Okada, Yoshinari Ohnishi (University of Tokushima), Hideki Hirakawa, Satoru Kuhara (Kyushu University), Tetsuya Hayashi (Miyazaki Medical College), and supported by the Research for the Future Program of the Japan Society for the Promotion of Science. The annotation was added by the NCBI Prokaryotic Genome Annotation Pipeline (PGAP). Information about PGAP can be found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/ Annotation Pipeline (PGAP) set; GeneMarkS-2+ repeat_region COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..20243 /organism="Bacteroides fragilis YCH46" /mol_type="genomic DNA" /strain="YCH46" /db_xref="taxon:295405" gene 1..885 /gene="rfbA" /locus_tag="BF_RS05145" /old_locus_tag="BF1094" CDS 1..885 /gene="rfbA" /locus_tag="BF_RS05145" /old_locus_tag="BF1094" /EC_number="2.7.7.24" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_005795876.1" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /codon_start=1 /transl_table=11 /product="glucose-1-phosphate thymidylyltransferase RfbA" /protein_id="WP_005795876.1" /translation="MKGIVLAGGSGTRLYPITKGVSKQLLPIFDKPMIYYPISVLMLAG IREILIISTPDDLPGFQRLLGDGSDFGVRFEYAEQPSPDGLAQAFIIGEKFIGDDSVCL VLGDNIFYGDGLTEMVQFAVNKADLENKATVFGYWVSDPERYGVAEFDRSGNVLSIEEK PQKPKSNYAIVGLYFYPNKVVEVAKNIKPSSRGELEITTVNQRFLSNRELKVQLLGRGF AWLDTGTHDSLSEASTFIEVIEKRQGLKVACLEGIALRKGWISPEKMKALAQPMLKNQY GQYLLKVIDDLFV" gene 1203..2732 /locus_tag="BF_RS05150" /old_locus_tag="BF1095" CDS 1203..2732 /locus_tag="BF_RS05150" /old_locus_tag="BF1095" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_011202254.1" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="WP_011202254.1" /translation="MKFRSGYFQLFINIFTNVIAFGTSLCVSFVLTPYLISNLGKDVYS FFPLANNFVNYMSIVIIALNSMAARFISIEIFKSNNVKAQEYISSIFISNVFLSVFLLF PAVLIVCSLETLLNIPNSSIPDVKLLFALIFLSMIVNTLSSVFGVSVFAKNRLDLKAYK EIIQGLLKGLLLLVLFLIYPPSIIYLGIVAVGLSFTNFGIDFIFTRKLFPTYVISFSYF RYNLVKEVLISGMWNSINSLGSILLLGMSLFLANILIGPDASGELSIVQTLSGFMCGII VLIYSVFLPRMTEKYANESYEHLAKEVRFSQKILSYFATTPTLLIILFGNSFFSLWMPG ENSDYLQCLSVISMIPLLVHGNMWTIYGLNMTLNKQKNPSITLILFGVLNIVLVYFDHI LLKGNLISLISISSFINVVYYLFYIPLYSTRQLGIKKIYFYSHMIKTFIFCLVVVIFGM IFKNSLYINSWGLFFFYNIIFGCLFLLLHVWFTLNRGEKEKLIVWVKKKIQ" gene 2729..3838 /locus_tag="BF_RS05155" /old_locus_tag="BF1096" CDS 2729..3838 /locus_tag="BF_RS05155" /old_locus_tag="BF1096" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_011202255.1" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /codon_start=1 /transl_table=11 /product="glycosyltransferase family 1 protein" /protein_id="WP_011202255.1" /translation="MKILYFFKEDDTYMTQWQRVHIFDELKHHNVNITVLNPSKYETVC QANEDLINLLRYNKDHYDLFMNCCGSDLLLPETMEALKDLSIPKLLICFDNLHAPYIHK DIAPFFDLVWLTSFETKSIFQKWGCNIIFLPYAANPYNFKNIYHRDILEVGFIGTPYGT RTLKLNQLLEHNIACRICGKLNNGSMEGKKVSNILTTIDSVKNLFSFSVGRKILQGKLL AKIKGNVELESKSEWLTISGPVSFDEMNRLYSNFALNLNILELRNTYLLKYPVYKLHLR TFEIPMCAGIQITTYNDELSSYFEEDKEIVFYRDLSELIDKCRFYLDAKKGNIRKMMRK NIRIRAEQEHTWWNRFTLIFDKLELGGKL" gene 3877..4824 /locus_tag="BF_RS05160" /old_locus_tag="BF1097" CDS 3877..4824 /locus_tag="BF_RS05160" /old_locus_tag="BF1097" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_005795870.1" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /codon_start=1 /transl_table=11 /product="glycosyl transferase" /protein_id="WP_005795870.1" /translation="MIVDYFDTVYSSINGRSPFATKLKIYSFFRWLIRVVANIVIPISF LLNRRKYCLKITSTTKKEKLIVSLTSFPKRINRLWIVIESIFRQSIKPDMVILWLSKEQ FPDRSFIPNSLLSLEKRGLIIELCEGDLRSHKKYYYALRQYPNDIIITIDDDVIYATDL ILNLLNQHQKYPNAICCTCASRIGIEDNKILPYISWECIDYEIPPSFGVLAIGVGGVLY PPGSLYHMFGEEDIFMKYCPTADDLWLNMMAHLKNTPISKTAYRSNYLPIIRFSKVSLS SVNNGMGANDIQLNRLITYFSLRLNQFPYSMLAK" gene 4821..6257 /locus_tag="BF_RS05165" /old_locus_tag="BF1098" CDS 4821..6257 /locus_tag="BF_RS05165" /old_locus_tag="BF1098" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_011202256.1" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /codon_start=1 /transl_table=11 /product="O-antigen polysaccharide polymerase Wzy" /protein_id="WP_011202256.1" /translation="MKIGTQMSTLSCSLKNREAILYVHIILICVCTIFYLYLFLNDIFY QKIAEFLVLFSFGWVYFSSGLLKIPFFHPYRMFLLTLFLYNISGIGLSFLNILDLFKDL ILGGVSNSFYTHSIIIEVFACITTFVLFIHLAVILYSYRKVSISTNTEWRYNRVMEKTG IYVFYIFLVPSLYYYYLLIAQYIAAGGYLYQSQVEGTVNTNILIRISDDFWFLGLILIL ASKAEIKKILFPVILYVLVFLLLSFVSGSRVYFVSLSLAIASYFCFRNLFSPKILIIIL AIFVSISMIIGVVRGASDYEQAFLKMRGEKKSENALIEFISQQASTMHIIGLTAFYVEN KKIDFSCRYLYDMLILPTGYIKGKPVGDYYLLSDRLALLTLKSDFSMGAGLGTSIIAEF YICGGICAVMLLSFIWGLFLMHIYSIAMRSNFYFLCFLLMLPGIYYTPRAHPLYPILSL MQPLILYGLIICFRKLAKSN" gene 6333..7559 /gene="wecC" /locus_tag="BF_RS05170" /old_locus_tag="BF1099" CDS 6333..7559 /gene="wecC" /locus_tag="BF_RS05170" /old_locus_tag="BF1099" /EC_number="1.1.1.336" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_005795861.1" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /codon_start=1 /transl_table=11 /product="UDP-N-acetyl-D-mannosamine dehydrogenase" /protein_id="WP_011202257.1" /translation="MDACFMGLGYIGLPTAIIAAKHGVKVTGVDINPKVVEMTNEGKLH IIEPGMQDILEEVVANGMLTASTIPTVSDAYFMVVPTPFKGDHEPDISYVEAATRAIIP FLKEGDLYVIESTSPVGTTGKMADLIFSLRPELRCKIYIAYCPERVLPGNVIYELVHND RVIGGIDERSTDKAIEFYSQFVKGKLHKTDCKTAEMCKLTENSSRDVQIAFANELSLIC DKAGINVWELIDLANKHPRVNILQPSCGVGGHCIAVDPYFITADFPIESQIIAKAREIN NYKAFWCAEKVENEMLKFEIKYGRKPIIAMMGLAFKPDIDDLREAPAKYITTKVMQSCN NADILVVEPNVVEHKVFKLTNYKDAYAKADIIVFLVAHSVFKTLLYDDNKVILDFCGIY KKQLSRSPL" gene 7556..8710 /gene="wecB" /locus_tag="BF_RS05175" /old_locus_tag="BF1100" CDS 7556..8710 /gene="wecB" /locus_tag="BF_RS05175" /old_locus_tag="BF1100" /EC_number="5.1.3.14" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_005930807.1" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /codon_start=1 /transl_table=11 /product="UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)" /protein_id="WP_005799504.1" /translation="MKKIMLVFGTRPEAIKMAPLVKEFQKYPKEFQTIVCVTGQHREML DQVLHLFHIRPNYDLNIMKQGQDLYDVTARVLIGMRDVLAEVRPDLLLVHGDTTTSTAA ALSAFYQQIPVGHIEAGLRTHNVYSPWPEEMNRQVTGRIATYHFSPTLLSRQNLLNEGV KGDFIIVTGNTVIDSIYMVVDRIRHDKLLEVQLRNVLSTSGYDVKRLSNDKKLVLITGH RRENFGDGFISMCQAIKALSEKYPNVDFVYPMHLNPNVRKPIHEVFGDELSDLNNLFFI EPLEYLSFVYLMEKSIIVLTDSGGIQEEAPGLGKPVLVMRDTTERPEALEAGTVKLVGT NYDKIVNEVSALLDDSDYYNTMSKAVNPYGDGKACSKIVNFLLA" gene 8707..9798 /locus_tag="BF_RS05180" /old_locus_tag="BF1101" CDS 8707..9798 /locus_tag="BF_RS05180" /old_locus_tag="BF1101" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_005795857.1" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /codon_start=1 /transl_table=11 /product="glycosyltransferase" /protein_id="WP_005795857.1" /translation="MSKVSVLILQHTVSAYNIPMYELLSEMVNLTVGYTRKNESNKVLP FNVKKLKSYLIGPFVFVPCLHSFCSNFDVVIYMPDMHFISYIMLCFLKRKYKLISWSIG IRASYSLRYDLDRPMTLLDRCFKLLLKKSDANIFYMKEPIAKWSHCGIDKSKLFVAHNT VAVNSIEIDSSFKKTILFVGSLYKEKKVDELIEAYETAFLEKGGEEGPILNIIGEGPEK VYLESLLKQKGLEKQIILRGAIYDETVIAEYFKEALICVSPDQAGLSVLKSMGYGVPFI TKKDAITGGEILNIENNKTGRLYQHRDELVKILQEVAEFPQKYIEMGILAMEYYKQNAS ISQMVQGFYDAISFVQIDNQWKN" gene 9786..10217 /locus_tag="BF_RS05185" /old_locus_tag="BF1102" CDS 9786..10217 /locus_tag="BF_RS05185" /old_locus_tag="BF1102" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_005795855.1" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /codon_start=1 /transl_table=11 /product="WxcM-like domain-containing protein" /protein_id="WP_005795855.1" /translation="MEELDNIKLIELPKFMDDRGNLTFIEKGNQVPFDIRRVYMIYDVP GGEIRGGHAYKKQVELVIALSGSFEVFLSDGFFERIYLLNRSYTGILIPAGIWRRLQNF STNSLALVLASTSYQESDYIRDYKSFLEYRDNEKKSVSI" gene 10192..10617 /locus_tag="BF_RS05190" /old_locus_tag="BF1103" CDS 10192..10617 /locus_tag="BF_RS05190" /old_locus_tag="BF1103" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_009133374.1" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /codon_start=1 /transl_table=11 /product="WxcM-like domain-containing protein" /protein_id="WP_011202258.1" /translation="MKKKVSVFDCSILELPRIKERCGNITPIHGLIDLPFEIARVFYLY DIPGGEDRGAHAHKECQQFLIAASGSYEVELNDGINKRTVLLNRPYYGLHIPPGIWAAE RGFSSGSICLVLASHIYDELDYIRDYDEYKNYMQNYI" gene 10614..11714 /locus_tag="BF_RS05195" /old_locus_tag="BF1104" CDS 10614..11714 /locus_tag="BF_RS05195" /old_locus_tag="BF1104" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_005795850.1" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /codon_start=1 /transl_table=11 /product="DegT/DnrJ/EryC1/StrS family aminotransferase" /protein_id="WP_005795850.1" /translation="MIKFLDLQKVTQRYSDEIQNSVARVVNSGWYLQGVENSSFEQKYS QYIGAKYTIGCANGLDALIWIFRAYIELGLMQPGDEIIVPSNTYIASILSITENGLIPV LVEPDINTYQIDDKKIEAAITNRTKAILIVHLYGQCAYTEKISTICKKFDLKLVEDNAQ AHGCIWGNQKTGSLGNAAAHSFYPGKNLGALGDGGAVTTDDEELANVVRALANYGSTKK YVFQYTGRNSRLDEIQAAVLNVKLKYLDKDNGYRKKIARYYIDNITNSQIILPKVSDWN AHVFHIFPVRCKKRNELQSYLAENGIQTIIHYPIPPHKQECYKAWNNLSFPVSEIIHKE ELSLPISPVLTDVEAKKIVSVINQFK" gene 11711..12706 /locus_tag="BF_RS05200" /old_locus_tag="BF1105" CDS 11711..12706 /locus_tag="BF_RS05200" /old_locus_tag="BF1105" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_011202259.1" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /codon_start=1 /transl_table=11 /product="GT0|GT46" /protein_id="WP_011202259.1" /translation="MMNFCTLFDSYYMHKGLALYRSLLKNCLDFHLYIMAFDFPCYEKL KNLGLNNVTIRYICDFETEELISLKDQRTKAEYCWTCGPAIIEYFIETFSLNNCTYLDA DLMFMASPQIIFDEFDKSVSIAISEHFHNETIGGKYCVQFMYFRNDIEGRKCLKWWKER CIEWCYARYEDGKYGDQKYLDSFPLLFENVYIIKNRGVGIAPWNMNFYTYDIKGENVIF NNRKYPCVFFHFHGTRVTCNSNELLLKAITYDVSPKIERCFFLPYLDLLLEVYRIYFNV NLSSVKVEKRMFWERFYSFIKRKCKHSKVMQFLYYKVFKIRYDGYESISK" gene 12708..13733 /locus_tag="BF_RS05205" /old_locus_tag="BF1106" CDS 12708..13733 /locus_tag="BF_RS05205" /old_locus_tag="BF1106" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_005829185.1" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /codon_start=1 /transl_table=11 /product="gnl|TC-DB|Q6MMD5|9.B.18.2.1" /protein_id="WP_011202260.1" /translation="MSLFKEKILLITGGTGSFGNAVLRRFLDSDIREIRIFSRDEKKQD DMRHHLQNPKVKFYIGDVRDKRSVDGVMNGVDYIFHAAALKQVPSCEFFPTQAVRTNVL GTENVLDSAIAHGVKNVVVLSTDKAAYPINAMGISKAMMEKVAIAKGRQLGNCGGTTIC CTRYGNVMASRGSVIPLWVEQIKKCNPITITDPNMTRFMMTLDDAVDLVLYAFQHGKNG DLFVQKAPAATLDVLADALKSLYHSNADVKVIGTRHGEKLYETLVTREEMSKAEDMGDY YRIPCDTRDLNYDKFFVEGSEEVSKIEDYHSHNTRRLDVEGMKELLLKLNFIREDLGLE K" gene 13778..14929 /locus_tag="BF_RS05210" /old_locus_tag="BF1107" CDS 13778..14929 /locus_tag="BF_RS05210" /old_locus_tag="BF1107" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_008157442.1" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /codon_start=1 /transl_table=11 /product="capsular polysaccharide biosynthesis protein CapF" /protein_id="WP_011202261.1" /translation="MKVLVTGAKGFVGRNLVSQLRNIQSGKAKNYALSGNELIIFEYDV DSAPSELDDYCRQADFIFNLAGVNRPLDQSEFMKGNFGFASTLLASLKRHGNTCPIMIS SSTQAALDNPYGASKRAGEQLLFEYSRETGSKVLVYRFPNVFGKWCRPNYNSAIATFCY NIAHDLPIQVNDPNVEMNLVYIDDVVDELISALTGNEHREGAYCKVSAVYTVTLGAIVE LLYSFRENRNNLGVPHVGDAFTKKLYSTYLSYLPKDGFGYPLKMNVDARGSFTEIIRST DRGQFSVNISKPHITKGNHWHHTKNEKFVVVSGQGVIRFRNVYDSSSEILEYFVSGDKL EIIDIPTGYTHNIENLGDTDMVTFMWCNECFDPGRPDTYFEEV" gene 14937..16121 /gene="wecB" /locus_tag="BF_RS05215" /old_locus_tag="BF1108" CDS 14937..16121 /gene="wecB" /locus_tag="BF_RS05215" /old_locus_tag="BF1108" /EC_number="5.1.3.14" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014547289.1" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /codon_start=1 /transl_table=11 /product="UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)" /protein_id="WP_011202262.1" /translation="MEIKLDYSDIKFRYDGKLRLLIIVGTRPEIIRLAAVINKCRRYFD CILAHTGQNYDYNLNGVFFHDLGLQAPDVYMDAVGDDLGSTMGNILNASYKLMSHLRPD AVLVLGDTNSCLSVISAKRLHIPIFHMEAGNRCFDECLPEETNRRIVDIISDMNLCYSE HARRYLNASGVAKERTYVTGSPMAEVLSENLSAIESSDIHARLGLRKGQYILLSAHREE NIDTDKNFASLFEGINAMAEKYDMPVLYSCHPRSRNRLESSGFKLDSRVIRHAPLGFHD YNCLQMHAYAVVSDSGTLPEESSFFTSVGHSFPAVCIRTSTERPEALDKGCFILAGIDK VSLLQAVDTAVEMNRNGDNGVPVPDYMDRNVSTKVVKLIQSYTGIVNKIVWRKS" gene 16132..17340 /locus_tag="BF_RS05220" /old_locus_tag="BF1109" CDS 16132..17340 /locus_tag="BF_RS05220" /old_locus_tag="BF1109" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_005807485.1" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /codon_start=1 /transl_table=11 /product="glycosyltransferase family 4 protein" /protein_id="WP_011202263.1" /translation="MNILFLTLNRVSDLSERGIYTDLMREFICHGHRVYMVVPAERRFH ESTSIKESCGAQILRVKTLNIQKSNVVEKGIGTLLLEMQYQCAIKRYWKDIRFDLILYS TPPITFNRVISSQKKRCKAKSYLLLKDIFPQNAVDLGMFSKRSLIYRLFRKKEKVLYQI SDFIGCMSPANVDYVLTHNPEIKADRVEICPNSIKLLEKPLMASTARKNILQKLHIPIN KTLFIYGGNLGRPQGLIFLLDVIAANEERNDSYFIIVGSGTEYGKIKSWFEANHPDNSM LLSSLPKKEYDDLVKACDVGLIFLDKRFTIPNYPSRLLSYLENRMPVLLATDLNTDIGR IAERNGYGFWTENGNLDTFMEMVDSLSADREKIKVMGEKGYEYLKSNYTVERGYRIIMK HFE" gene 17343..17951 /locus_tag="BF_RS05225" /old_locus_tag="BF1110" CDS 17343..17951 /locus_tag="BF_RS05225" /old_locus_tag="BF1110" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_007485209.1" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /codon_start=1 /transl_table=11 /product="gnl|TC-DB|H8E4X1|9.B.18.1.2" /protein_id="WP_011202264.1" /translation="MYQYVIKRLIDFVVVFFVLIIIWPVLLLVTLWLHFANKGAGAFFL QERPGRHGKIFKVIKFKTMTDERDAEGNLLPDDKRLTKVGKFVRSTSIDELPQLINVLK GDMSFIGPRPLLPQYLPLYNKEQARRHEVRPGITGWAQVNGRNAISWVRKFELDVWYVD HCSFFLDLKIFFLTIKKVFVREGISSDTAVTMEPFTGNN" gene 17964..18548 /locus_tag="BF_RS05230" /old_locus_tag="BF1111" CDS 17964..18548 /locus_tag="BF_RS05230" /old_locus_tag="BF1111" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_005807481.1" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /codon_start=1 /transl_table=11 /product="acetyltransferase" /protein_id="WP_005795841.1" /translation="MFLYGASGHAKVIIDILRAGHESIEALFDDNVEVTSLLGHPVLRP SEVRGPLIVSIGNNRIRKRIVDTLSVEFGCAIHPLSIVSELADIGEGSVVMQGSIIQVC AQVGRHCIINTGASVDHECVIEDYVHISPHSTLCGNVLVGEGSWIGAGTTIIPGVKIGK WSVIGAGSVVTKDIPDHVLAVGNKCKIIKSI" gene 18562..19692 /locus_tag="BF_RS05235" /old_locus_tag="BF1112" CDS 18562..19692 /locus_tag="BF_RS05235" /old_locus_tag="BF1112" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_007485218.1" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /codon_start=1 /transl_table=11 /product="aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme" /protein_id="WP_011202265.1" /translation="MNKRIWLSLAHMGGREQDFIKEAFDTNWVVPLGPNVDAFEQSLVE YLHEDRYVVALSAGTAALHLGLILLDVKPGDEVICQSFTFAASANPISYLEAKPVFVDS EKDTWNMDPVLLEEAIKDRLRKTGKLPKAIIPVHLYGMPAKMDEIMDIAGRYGIPVLED AAEALGSELNGRKCGTFGELAALSFNGNKMITTSGGGALVCRTEEEARQTKFYATQARD AAPHYQHTHIGYNYRMSNICAGIGRGQMFVLDEHIARRRAIHSLYVDLLKDVAGITVME NPDSRFASNFWLTCILVDPKLAGKSREDIRLRLDSENIETRPLWKPMHLQPVFTDAPFY GNGTSERLFDIGLCLPSGPTLTDEDIRRVVDTIRKM" gene 19740..20243 /locus_tag="BF_RS05240" /old_locus_tag="BF1113" CDS 19740..20243 /locus_tag="BF_RS05240" /old_locus_tag="BF1113" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_011202266.1" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /codon_start=1 /transl_table=11 /product="hypothetical protein" /protein_id="WP_011202266.1" /translation="MFQPIFYIQLYEMKHEDYIDKINSLTTAVNQFKESYSLLKFSLEA SEKRNESLQFQVTRLQDIICIFTDEISGLRVEEFNRISYIECTRFDVVDYEDEYMHESG QYLFFCWAYVRAKFKYAEEISKDLDAAWFVEQIGLLYMYISYRNGNNQNAWSGSQRLSD TCFP" ORIGIN 1 atgaaaggta ttgttttagc aggtgggtcg gggacacggt tatatcctat aactaaagga 61 gtgagtaagc agttgcttcc tatctttgat aaacctatga tttattatcc tatttctgta 121 ctaatgttgg caggtatacg ggaaattctc attatttcta ctccagatga cttgccggga 181 tttcaacgtt tattgggtga cggatctgat tttggggtga ggtttgagta tgcagagcaa 241 ccttcacctg atggtttggc acaagctttt atcataggag aaaaatttat aggggatgat 301 tctgtctgtt tggttttagg tgataatatt ttttatggag atggtttgac cgaaatggtt 361 cagtttgctg tgaataaggc tgacttagaa aataaagcaa ccgtttttgg ttattgggta 421 agtgatcccg aacgttatgg tgtagcggaa tttgatagga gcgggaatgt tctcagcata 481 gaggagaagc ctcagaaacc taaatctaat tatgccattg taggactata tttctatcct 541 aataaggtgg ttgaagttgc gaagaatatt aaaccctctt ctcgtggaga gctagaaata 601 acaactgtca atcagaggtt tctatcaaat agagagctaa aagtgcaatt gttaggtcga 661 ggatttgctt ggcttgatac aggtacacat gattctttat ccgaagcaag tacttttatt 721 gaagttattg agaaacggca aggtttaaaa gttgcatgtt tggagggaat tgctctaagg 781 aaaggttgga tttcgccaga aaagatgaaa gcattggcac agccaatgct taagaatcaa 841 tatgggcagt atctattgaa agttattgat gatttatttg tataataaaa ttgtttgttt 901 tttatatata acaaacagag ttattaagcc ctttattatc gttaattttt ggtatttatg 961 ggtaatattt gtaaatactt ttgttgttgt aaagtataat ggctcataga aaatttgtac 1021 atcgtaataa tagataagat tacatatttg atggtatcct cttcattatt tcaatcagtt 1081 gtttttatag aaattacacc atgctaccaa gtgtgttttt cgaaaatata ataagaaatg 1141 aaataatagg tatattgaaa agttgagaag agaattagta atcaaatacg agatgaatag 1201 aaatgaaatt tagatctgga tattttcaat tatttatcaa tatatttact aatgtaattg 1261 cgtttggaac ttctttatgc gtttcatttg tcttaacacc ttatctgatt agcaatttag 1321 gaaaggatgt atattcgttt ttcccattag ctaataattt tgtaaattat atgtctattg 1381 ttattattgc tttgaattcc atggctgccc gatttatttc cattgaaata ttcaaaagta 1441 ataatgtaaa ggctcaggaa tatatttctt ctatttttat ttctaatgtg tttctttccg 1501 tatttttact gtttccagct gttttgattg tttgctcttt ggaaacttta ttgaatatcc 1561 caaacagctc tattccagat gtaaagttac tttttgcctt aatattttta tcgatgatag 1621 taaatacact aagttctgtt tttggtgttt cggtatttgc taaaaataga cttgatctca 1681 aagcatataa agaaattatt caaggtttac tcaaaggcct tttgctttta gttctttttt 1741 taatttatcc tccttcaatt atctatttgg gtatagttgc tgtaggattg agttttacta 1801 attttgggat agatttcata tttactagaa agttgtttcc tacttatgtg atttctttct 1861 cctatttccg atataattta gtaaaggaag tcttgatttc cggtatgtgg aattctataa 1921 attctctagg ctctattcta ttattaggaa tgtctttatt tttagctaat atattaattg 1981 gtccggacgc ctctggagaa ctgtcaattg ttcaaacttt atcaggattt atgtgtggta 2041 taattgttct tatttattct gtttttttac ctagaatgac ggaaaagtat gcaaatgaaa 2101 gctatgaaca tttggcaaaa gaagtgcgat tctctcaaaa aatattgagc tattttgcaa 2161 caacaccgac tcttctgatt attctgtttg gaaatagttt tttttctttg tggatgcctg 2221 gggaaaattc ggattatttg caatgtttat ctgtcatttc tatgattcct ttattagtgc 2281 acggaaatat gtggactatt tatgggctga atatgacatt gaataaacaa aagaatccct 2341 ccattacctt gatcttattt ggcgtactga atattgttct agtctatttt gatcatattc 2401 tattaaaggg aaatttaatt tccttaatat caattagctc gttcataaat gttgtttact 2461 acttatttta tattccattg tattcaacaa gacaattggg aataaagaaa atctattttt 2521 attcccacat gattaaaaca tttatttttt gtttggtggt ggtcatattt ggaatgatat 2581 ttaaaaacag cctatatatt aattcttggg gacttttctt tttttataat attatttttg 2641 gttgtttgtt tcttttgttg catgtatggt ttactttaaa tcgtggggag aaggaaaagt 2701 taattgtttg ggtgaaaaag aaaatacaat gaagatactc tattttttta aagaagatga 2761 tacttatatg actcaatggc aaagagttca tatatttgat gaattgaagc atcataatgt 2821 gaatattaca gttttaaatc cgtcaaaata tgaaactgtt tgtcaggcaa atgaggacct 2881 gattaatctg ctaagatata ataaagatca ttatgactta tttatgaatt gttgtggctc 2941 tgacttatta ttacctgaaa cgatggaagc cttaaaggat ctgtctatac ctaaacttct 3001 aatttgcttt gataatcttc atgcccctta tattcataaa gatattgccc cttttttcga 3061 tttggtttgg ttaacctctt ttgaaactaa gagtatattt caaaagtggg gatgtaatat 3121 aatattttta ccttatgctg ctaatcctta taattttaaa aatatatatc atagggatat 3181 tttggaggtg ggatttatcg gaacccctta tggaactcga acgttgaaat taaatcagct 3241 tttagagcat aatatagctt gccggatttg tgggaagtta aataatggta gtatggaggg 3301 aaaaaaagta agtaatatat tgacaactat cgattctgtt aagaatttgt tttctttctc 3361 tgttggtaga aaaatattac aaggaaaatt gttggctaaa ataaaaggga atgtagagtt 3421 ggaaagtaaa agtgaatggc ttaccatttc tggcccagta tcatttgatg aaatgaacag 3481 actttattcg aattttgctt taaatctaaa tatactggaa ttaagaaata cttatttact 3541 taaatatcct gtgtataaac ttcatttgcg gacatttgaa attcctatgt gcgctgggat 3601 tcaaatcaca acttataatg atgaattatc ctcttatttt gaagaagata aggaaattgt 3661 attttataga gatttaagtg agcttattga taagtgcagg ttttatcttg atgcgaagaa 3721 aggtaatata cgcaaaatga tgcgaaaaaa tataagaata agagcagaac aagagcatac 3781 ttggtggaat cgttttactc taatttttga taaattagaa cttggtggaa aactttgaaa 3841 cttttagctt attgattaat aattttaatt gtaaaaatga ttgttgatta ttttgatact 3901 gtttattctt caataaacgg tcggtctcct tttgctacga aattgaagat atattctttt 3961 tttcgttggt tgattagagt ggtagctaat attgttattc ctattagttt tttattgaat 4021 aggagaaagt attgtttaaa aataacttct actactaaaa aagagaaact tattgtatct 4081 ttaacttctt tccctaaaag gataaatagg ctttggattg tgattgaatc tatttttcgt 4141 caatcgatta aaccggatat ggttatttta tggctatcta aagagcaatt tcctgacagg 4201 agttttatac ctaattcatt gttatcatta gaaaaaagag ggttaataat agaactgtgt 4261 gagggagatt tgcgctctca taagaaatat tactatgcgt tacgccagta tcctaatgat 4321 attatcataa caattgatga tgatgttatt tatgctactg atttgatact caatttattg 4381 aatcagcatc aaaaatatcc taatgcaata tgttgtacct gcgcttcacg tattggaatc 4441 gaagataata aaatcctccc ttacatttca tgggagtgta ttgattacga aatacctcca 4501 agttttggag tactagctat aggggtaggg ggagttttgt atccccctgg aagtttatat 4561 catatgtttg gagaggagga tatttttatg aagtattgtc ctactgctga tgatttatgg 4621 ttgaatatga tggctcactt aaagaatact ccaatttcga aaacggcata tcgttcgaat 4681 tacttaccga ttataagatt tagtaaagtg tctttatcat cagtaaataa tggtatggga 4741 gctaatgaca ttcaattaaa tcgtttgata acttattttt ctttaagact taatcaattt 4801 ccttattcaa tgttggccaa atgaagatcg ggactcagat gagtacttta tcttgttctt 4861 tgaaaaatag agaggctatt ttgtatgtac acattatact tatatgtgta tgtacaatat 4921 tctacttgta tttattttta aatgatattt tctatcaaaa aatagcagaa tttttagtgt 4981 tattttcttt tggatgggta tatttttcat caggtttact aaaaattcct ttttttcatc 5041 cttatcggat gtttctgttg acactatttc tttataatat aagtggtatt ggcttgagct 5101 ttttaaatat attagatcta tttaaggatt taatactagg tggagtcagt aactcttttt 5161 atacgcactc aattattata gaggtatttg cgtgtattac aacctttgtt ctttttatac 5221 atttagctgt tatcttgtat agctatagga aagtttcaat atcgacaaac accgaatgga 5281 gatataatcg agtaatggaa aagacaggaa tatatgtatt ttatatattt ttagttccat 5341 cactttatta ttattatttg ctaatagcgc aatatattgc tgctggtgga tatttatatc 5401 aatctcaagt ggaaggtact gtaaatacta atattttaat tcgtatatct gatgattttt 5461 ggtttttagg tttgattctt attttggctt caaaagcaga aataaagaag atattatttc 5521 ctgtaattct ttatgtttta gtattcttat tattgtcatt tgtttcagga agtagagtct 5581 attttgtttc attatcactt gctatagcaa gttatttttg ttttagaaat ttattttctc 5641 caaaaatatt aataattatt ttggcaatat ttgtatcaat atctatgatt attggtgtag 5701 ttcgaggagc cagtgattat gagcaagctt ttttaaaaat gagaggagaa aaaaaatctg 5761 agaatgcgtt gattgaattc atttctcagc aagcttctac aatgcatatt attggattaa 5821 ctgcttttta tgtagagaat aagaaaattg acttctcatg tcgatactta tatgatatgt 5881 tgatcttgcc aactggatac ataaaaggaa aacctgtagg agattattat ttattatcag 5941 ataggttggc tcttcttaca ttgaagtctg acttttctat gggcgctgga ttaggtacat 6001 ctattattgc agaattttat atatgtggag gcatttgtgc tgtaatgtta ctttccttca 6061 tctgggggct atttttgatg catatttatt ctatagcaat gagatctaat ttttattttt 6121 tatgcttttt attgatgcta ccgggaatat attatactcc tagggctcac cctttatatc 6181 ctatactatc attaatgcaa ccattaatat tatatggatt aattatatgc tttaggaaat 6241 tagcaaaaag taattgaaat actcttctta atttatatac ttatgtgatt gtaagttatt 6301 ttattattct gtaaactatt aatattggaa atatggatgc ttgttttatg gggctaggct 6361 atattggtct acctacagct attattgctg caaaacatgg ggtaaaagta acgggagtgg 6421 atataaatcc caaagtggtt gaaatgacta atgaagggaa gttacatatt atagagcccg 6481 ggatgcaaga tatacttgag gaagtagttg cgaacggaat gctgacggct tcaactatac 6541 cgacagtaag tgatgcctat tttatggttg tacctacacc atttaaagga gatcacgaac 6601 ctgatatttc ttatgtagaa gctgctactc gtgctattat tccttttttg aaagaaggag 6661 atttatatgt aattgaatct acttctcctg tggggacaac tggtaaaatg gctgacttaa 6721 tcttttcact tcgtccagaa cttaggtgta aaatttatat agcatactgt cctgaacgtg 6781 ttttacctgg taatgttata tatgaattag tacataatga tcgggtgatt ggaggaatcg 6841 atgaacgatc tactgataaa gcaatagaat tttatagtca atttgtgaaa ggtaaacttc 6901 ataaaacaga ctgtaagaca gcagaaatgt gtaagttaac agagaactct tctcgtgatg 6961 tacagattgc gtttgccaac gagttatctt tgatttgtga taaagctggt attaatgtat 7021 gggaactgat tgacttggct aataaacatc ctagagtaaa tattttacaa ccaagctgtg 7081 gcgttggagg acattgcatt gcagtagatc cttattttat aacagcggat tttcctatag 7141 aatcccaaat aatagcaaaa gctcgtgaaa ttaacaatta caaagctttt tggtgtgctg 7201 aaaaagttga gaatgaaatg ttgaaatttg agattaaata tggtcgtaag ccaattattg 7261 ctatgatggg cttagccttt aagccagata ttgatgattt gcgtgaggct cctgctaaat 7321 atataacaac aaaagtaatg caaagctgta ataatgctga cattttggtt gtagagccta 7381 atgtagtaga acataaagtc tttaaattaa caaattataa agatgcatat gcaaaagccg 7441 acattatcgt ttttttagtg gctcattcag tatttaaaac attgctatat gatgataata 7501 aagtgatttt agacttttgt ggtatctata aaaaacaatt atctcgttca ccattatgaa 7561 aaaaattatg ttggtattcg gtactcgtcc cgaagccatt aaaatggcac ctctagtaaa 7621 agagttccag aaatatccaa aggagtttca aactatagtt tgtgttacag gacagcatcg 7681 tgaaatgctt gatcaagttt tacatctttt tcatattcgt cctaattatg acttgaacat 7741 catgaagcaa ggacaagatt tatatgatgt aactgctcgt gtcttgatag ggatgcgtga 7801 tgttttggct gaagtgcgac cggatctgtt attagttcat ggtgatacga caacttctac 7861 tgctgctgct ttgtccgcct tttatcagca aatacctgtc ggacatatag aagcggggtt 7921 acggacccat aatgtatata gtccttggcc agaagaaatg aataggcagg ttacagggcg 7981 tattgcgact tatcattttt cacccacttt attaagtcgc cagaacttat tgaatgaagg 8041 agtgaaagga gattttatta ttgtgacagg taatacggta attgattcta tttatatggt 8101 tgtggataga ataaggcatg ataagttatt agaagtacaa ttaagaaatg ttttgagtac 8161 ttctggctat gatgtcaaac gtctatctaa tgataaaaaa ttagtattaa taactggtca 8221 tcgtagagaa aattttggtg atgggtttat atctatgtgt caagctataa aagcattaag 8281 tgaaaaatat cctaatgtcg attttgtata tccaatgcat ttgaatccta atgtccgtaa 8341 acctattcat gaagtattcg gagatgaatt atcagatttg aataatctgt tttttattga 8401 accattagaa tatctctctt ttgtgtacct gatggaaaaa tctataattg tattgacaga 8461 cagtggtgga atacaggaag aggctccagg tcttggtaag ccagtattgg taatgcgtga 8521 cacaacagaa cgtcctgaag ccttagaagc tggaactgta aagttagtag ggactaatta 8581 tgataaaata gttaatgagg tttcagcttt acttgatgat tcagactatt ataacactat 8641 gagtaaagct gttaatcctt acggggatgg aaaggcttgt tcgaaaattg ttaatttttt 8701 gttggcatga gtaaagtttc tgtactaata ttgcagcata ctgtttctgc atataatata 8761 cctatgtatg aactcttatc agaaatggta aatttaacag ttggatatac gagaaagaat 8821 gaatctaata aagtacttcc gtttaatgtc aagaagttga agtcatattt gattggtcct 8881 tttgtttttg ttccttgcct acattccttt tgctcaaatt ttgatgtggt tatatatatg 8941 cctgatatgc attttattag ctatataatg ctttgttttt tgaaaaggaa atataaactc 9001 atttcttgga gtatagggat aagagcttct tatagtttga ggtacgatct tgatcgccct 9061 atgactctat tggacagatg tttcaaattg cttctgaaaa aatcagatgc taatatattt 9121 tatatgaaag agcctatagc aaaatggagt cattgtggta ttgataaatc aaaacttttt 9181 gttgctcata atacagttgc tgtaaattct atagaaatag atagctcttt taagaaaacg 9241 attttatttg taggctcttt atataaagag aagaaggttg atgaattaat agaagcctat 9301 gaaacagcct ttttagaaaa agggggtgag gaggggccta ttttaaatat tattggtgaa 9361 ggacctgaaa aagtatattt agaaagtctg ttgaaacaaa aaggattaga aaaacaaatt 9421 attttacgtg gtgcaattta tgatgaaaca gttattgcgg aatattttaa agaagcatta 9481 atttgtgttt cccctgatca agctggttta tcagtattaa aaagtatggg atatggtgta 9541 ccttttataa ctaaaaaaga tgcgattact ggaggagaaa tactaaatat agaaaataat 9601 aagacgggac gtttatatca acatcgtgat gaacttgtga aaatattaca agaggttgcg 9661 gaatttcctc aaaaatatat tgaaatggga atcttggcta tggaatatta taagcaaaat 9721 gcttctattt cacaaatggt tcaaggcttt tatgatgcaa ttagttttgt acagattgat 9781 aatcaatgga agaattagac aatattaagt taatcgagtt acccaaattc atggatgatc 9841 ggggaaattt aacattcata gaaaaaggta atcaagtgcc ttttgatatt cgaagggtat 9901 atatgattta tgatgttcct ggtggcgaaa ttagaggagg tcatgcatat aaaaaacaag 9961 tggagttagt cattgctttg tctggaagtt ttgaagtttt tttaagcgat ggattttttg 10021 agcgcattta tcttttaaat cgttcttata cgggaatact cattcctgct ggtatatggc 10081 gtaggttgca aaacttttca acaaattctc ttgctttagt attagcttct acttcttatc 10141 aagagtcgga ttatattcgt gattataaat catttttgga gtaccgtgat aatgaaaaaa 10201 aaagtgtcag tatttgattg ttcaatatta gaattgccta gaataaaaga gcgttgtgga 10261 aatattactc ctatacatgg actaatagat cttcctttcg aaattgctcg tgttttttat 10321 ttgtatgaca taccaggagg agaagatcgt ggtgcacatg ctcataaaga atgtcaacag 10381 tttctgattg cagctagtgg tagttatgaa gttgaactaa atgatgggat taataaaagg 10441 actgtacttt taaatagacc atattatgga ttacatattc ctcctggtat ttgggccgct 10501 gaaagaggtt tttcttcggg atctatttgt ttggtcttag cttctcatat ttatgatgag 10561 ttagattata ttcgtgatta tgatgagtat aaaaattata tgcaaaatta tatatgataa 10621 agtttttaga tttacaaaaa gttactcaga gatactcaga tgaaatccaa aattctgtgg 10681 ctcgagttgt aaactctggt tggtatttgc aaggtgtaga gaatagtagc tttgagcaaa 10741 agtattcgca atatataggt gccaaatata ctatagggtg tgccaatggt ttagatgctc 10801 ttatttggat atttcgggca tatattgaat taggattaat gcaaccagga gatgagataa 10861 tagtaccttc taatacatat atcgcttcta ttttgtctat aacagagaat ggtttaattc 10921 cagttcttgt tgaaccagac ataaatactt atcaaattga tgataaaaaa atagaggcgg 10981 ctattacgaa taggaccaaa gctattttga tcgtccatct ttatggacaa tgtgcttata 11041 ctgaaaaaat tagcactatt tgtaagaaat ttgatttaaa attagttgaa gataacgctc 11101 aagctcatgg atgtatatgg gggaaccaga agacaggttc tttagggaat gcagcagcac 11161 atagctttta tccaggaaaa aatttaggtg ctttgggaga tggaggggct gttacgacgg 11221 atgatgaaga acttgcaaat gtggttcgcg ctttagcaaa ttatggctct actaagaaat 11281 atgtatttca atatacaggt cgtaatagta gattggatga gatacaagcc gcagtgctta 11341 atgtaaaatt gaagtattta gataaagata atggttatcg aaaaaaaata gcgcgatatt 11401 atattgataa tattactaat tctcaaataa tattacctaa agttagtgat tggaatgcac 11461 atgtttttca tatttttcca gtacgctgta aaaaacgtaa tgaattgcag agttatttgg 11521 ctgaaaatgg cattcaaaca attattcatt atcctatacc tcctcataag caagagtgtt 11581 ataaagcttg gaataactta tcttttcctg tatcagaaat aatccataaa gaggaattaa 11641 gcttaccaat cagtcctgtt ctgacagacg ttgaagcaaa aaaaattgta tctgtaataa 11701 atcaatttaa atgatgaatt tttgtactct ttttgactct tattatatgc ataaggggct 11761 tgctttgtat agatcgttgt tgaaaaattg tttagacttt catttgtata taatggcttt 11821 cgactttcct tgttatgaga agttgaagaa tttagggttg aataatgtta ctataagata 11881 tatttgtgat tttgagacag aagaacttat ttcattaaaa gatcaaagaa cgaaggcgga 11941 atactgctgg acctgtggac ctgcaattat tgagtatttt attgagacat tttcgctgaa 12001 taattgtact tatcttgatg ctgatttaat gtttatggca tcacctcaga taatttttga 12061 tgagtttgac aagtcagtat ctattgctat ttcagaacat tttcataatg aaacaattgg 12121 tgggaaatat tgtgtccaat ttatgtattt taggaatgat atagaaggga gaaaatgttt 12181 aaaatggtgg aaagagagat gtattgaatg gtgttatgca cggtatgagg atgggaaata 12241 tggagatcag aagtatttgg attcttttcc tctattattt gagaatgttt atatcattaa 12301 aaatcgaggt gtaggcatag ctccttggaa tatgaatttt tatacatatg atattaaagg 12361 ggaaaatgta atatttaaca ataggaaata tccttgtgtc ttttttcatt ttcatggaac 12421 tagggttact tgtaattcta atgaattgtt gttaaaggct attacatatg atgtttctcc 12481 taaaatagaa cgctgtttct ttttaccgta tttagacttg ctgttagaag tttaccgtat 12541 ttactttaat gtaaatttga gttcagtaaa ggtcgaaaaa agaatgtttt gggaacgttt 12601 ttattctttt ataaaacgaa aatgtaagca tagtaaggtt atgcagtttt tatactataa 12661 agtgtttaaa atacgatatg atggatacga atctataagt aaataatatg tcattattta 12721 aagagaaaat tttattaatt accggtggaa caggttcctt cggtaatgcc gtactacgtc 12781 gttttcttga ttctgatatc agggagattc gtatattctc tcgtgatgaa aagaaacaag 12841 atgatatgcg tcaccatctt cagaatccca aagtaaaatt ctatattggc gatgtccgtg 12901 acaagcgctc tgtggatgga gttatgaatg gagtggatta tatcttccat gccgctgcgc 12961 tgaagcaagt tccttcctgt gagttttttc ccacacaagc ggttaggaca aatgttctcg 13021 gtacagaaaa tgtgttggat tccgccatag ctcacggtgt taaaaatgtg gtggtacttt 13081 ctaccgataa agctgcctat cctataaatg caatgggtat cagcaaagcc atgatggaga 13141 aagttgctat cgccaaaggt cgtcagttgg gtaattgtgg aggaacaacg atttgctgta 13201 cccgttatgg gaatgttatg gccagtcgtg gttctgtgat acccttgtgg gtagagcaaa 13261 ttaagaaatg taatccaata acaataaccg atcccaacat gacccgcttc atgatgactc 13321 tggatgatgc tgtcgacttg gtgctttatg cctttcagca tggaaaaaat ggtgatttgt 13381 ttgttcagaa ggcgcccgct gctactctgg atgtattagc cgatgcatta aagtctcttt 13441 accatagtaa cgcggatgtc aaagtgattg gtacccgtca cggtgagaaa ctctatgaaa 13501 ctcttgttac ccgtgaagag atgtctaaag cagaggatat gggtgattat tatcgtatcc 13561 catgtgatac gcgtgattta aattatgata agttttttgt ggaaggaagt gaggaggtct 13621 ccaaaataga agattaccat tctcataata cccgtcgtct tgatgttgag gggatgaaag 13681 aacttctctt gaaacttaat tttattcgcg aagatcttgg ccttgaaaaa tagaattgat 13741 agcaatcaag gtcaaataaa ttaattcctc tttatttatg aaagttttag taaccggtgc 13801 gaaaggtttt gtcgggcgga atcttgtatc ccaattgcgc aatattcaaa gtggcaaagc 13861 aaaaaattac gctttgtccg gaaacgagtt gatcattttt gaatatgatg tagatagtgc 13921 cccttctgaa ttggatgact attgccgaca ggctgatttc atttttaatc tggccggtgt 13981 aaaccgtcca ctggatcagt ctgaatttat gaaagggaac tttggttttg cttctacgct 14041 tcttgcttca ttgaagagac atggaaatac ttgccctatc atgatatcct cttctacaca 14101 agccgctttg gataatcctt atggagcctc taaacgggcg ggtgaacaat tgttgtttga 14161 gtattcccgg gaaacgggat cgaaagtgtt ggtataccgt tttcccaatg tctttggtaa 14221 atggtgccgc cctaattata atagtgcaat agctactttt tgctataaca tagcacatga 14281 tcttcccatt caggtcaatg atccgaatgt ggagatgaat cttgtatata tagatgatgt 14341 tgtggatgaa ttaatctctg ctttgacggg caatgaacat cgggaaggag cttattgtaa 14401 agtatctgct gtatacactg ttactttggg agcaattgtg gaattgctat attctttccg 14461 tgagaaccgt aacaatttgg gagttcccca tgtgggagat gcttttacta agaaacttta 14521 ctccacctat ctctcttatc tgccgaaaga tggatttggc tatcctttga agatgaatgt 14581 ggatgcccgt ggcagtttca cggagattat tcgcagtacg gaccggggac agttctcggt 14641 taatatttcc aagccacata ttacaaaagg taaccattgg catcatacca aaaacgaaaa 14701 gtttgtggtt gtaagtggcc aaggtgtcat ccgttttcgt aacgtgtatg attcatcctc 14761 tgagattcta gaatattttg tttcaggtga taagcttgaa ataattgata ttcctaccgg 14821 ttatacccat aatattgaga acctgggtga tacggatatg gtaactttta tgtggtgtaa 14881 cgagtgtttt gatcccggta ggccggatac ttattttgaa gaagtttaat agcattatgg 14941 aaatcaaact ggattattca gatatcaagt ttcggtatga tggcaagctg agactgttga 15001 ttatagtcgg tacccgtccg gagattatcc ggttggctgc cgtaataaat aaatgccgtc 15061 gatattttga ttgtattttg gctcataccg gacagaatta tgattataat ctgaacggag 15121 tcttttttca tgacctgggc ttacaggctc cggatgtcta tatggatgct gtaggggatg 15181 atttgggttc gacaatgggt aatattttga atgcgagcta taaactgatg tcacacttac 15241 gccctgatgc cgttttggtt ctcggtgata ccaattcttg cctaagtgta atcagcgcta 15301 aacgcttgca tattcctatt tttcatatgg aagccggtaa ccgttgcttt gatgagtgcc 15361 ttcctgaaga gacaaaccgg cgtattgtag acattatttc tgatatgaat ctttgctatt 15421 cggagcatgc cagacggtat ctgaatgctt cgggtgtggc aaaggaacgt acttatgtaa 15481 ccggttctcc gatggccgag gttctgtctg agaacctttc tgctatagaa tcttcggata 15541 tccacgccag attgggtttg aggaaaggac aatatatcct gctgtctgca catcgggaag 15601 agaatattga tactgacaag aacttcgctt cattgtttga aggcataaat gcgatggctg 15661 aaaagtatga catgcctgta ctttacagtt gccatcctcg tagccgtaac cgcctggaat 15721 caagtggatt taaactggat agccgggtga ttcggcatgc ccctctgggg ttccatgact 15781 ataactgctt gcagatgcat gcttatgccg tggtcagtga tagcgggaca ttaccggagg 15841 aaagttcttt tttcacttct gtcggtcact cttttccggc tgtttgtatt cgcacaagta 15901 ccgaacgtcc cgaagctttg gataagggat gttttattct tgcggggatt gataaagtct 15961 ctttgcttca agctgtagat actgctgtgg aaatgaatag gaatggtgat aatggtgtcc 16021 ctgttccgga ttatatggat cgaaatgtat cgacaaaggt ggtgaagttg attcaaagtt 16081 atacaggaat agtaaacaaa attgtctgga gaaaatcctg ataatatcga aatgaatatt 16141 ttgtttctga cccttaaccg tgtttcagat ctttctgaac gggggatata cacggatttg 16201 atgcgggaat ttatttgtca tgggcatagg gtctatatgg ttgttcccgc cgaacgtcgc 16261 tttcatgaat ctacttcaat aaaagagagt tgtggcgctc aaatattgag ggtgaagaca 16321 ttgaatatcc aaaagagcaa tgtggtggag aaaggcatcg gtacgttgtt attggagatg 16381 cagtatcaat gtgccataaa aagatattgg aaggatatcc ggtttgattt gatactttat 16441 tcaactcctc ccattacttt caatagggtc atcagttcac aaaagaaacg ctgtaaggcg 16501 aaaagttatc ttttattgaa agatattttt cctcaaaatg cagttgattt gggaatgttt 16561 tcaaagagaa gcttaattta tagacttttc cgtaaaaaag agaaagtttt atatcagata 16621 tcggacttta taggctgtat gtctcctgcc aatgtggatt atgtgttgac acataatccg 16681 gaaataaagg ctgatagagt agagatatgc cccaatagta ttaaattgtt agagaagcca 16741 ttaatggctt caactgcaag aaaaaacata ttgcagaaat tgcatattcc aattaataag 16801 actcttttta tatatggtgg caatttgggg cgtccacaag gtctgatttt cttgttggac 16861 gtgatagccg caaatgagga acgtaatgac agttatttca tcattgtagg cagtggcact 16921 gaatatggca agataaagtc ttggtttgag gcgaatcatc cggataattc aatgctgctt 16981 tcttcacttc caaagaaaga gtatgatgat ttggtaaagg cttgtgatgt cggtttgatt 17041 ttccttgata aacgttttac catccctaat tacccttccc gtttactctc ttatttagaa 17101 aaccggatgc ccgttttatt ggctacagac ctgaatacgg atatcggacg gattgctgaa 17161 cggaatggtt atggcttttg gacagaaaat gggaatttgg atacatttat ggaaatggtg 17221 gattccttat ctgcagacag agaaaaaata aaagtgatgg gcgagaaagg gtatgaatat 17281 ttgaagtcta attatacagt agaaagaggg taccggataa taatgaaaca ttttgagtag 17341 gtatgtatca gtatgttatt aaacgattaa tcgattttgt agtcgtgttt tttgtcctga 17401 ttattatctg gcctgtattg cttctcgtaa ctctttggct tcattttgcc aataaaggtg 17461 ccggtgcttt ttttcttcag gagaggcccg gaaggcatgg taaaatcttt aaagtcatca 17521 aatttaaaac catgacagat gaacgtgatg cagaagggaa cttacttccg gatgataaac 17581 gattgacgaa ggttggtaag tttgttcgtt ctacttcgat tgacgaactc ccacaattaa 17641 tcaatgttct gaagggtgat atgtccttta ttggtccccg tccgttgtta cctcaatatc 17701 ttcctttata caataaagaa caggctcgtc ggcatgaagt ccgtcccggg ataaccggtt 17761 gggctcaggt gaatggacga aatgccattt cgtgggtaag gaagtttgag ttggatgtct 17821 ggtatgtaga ccattgttct ttttttctgg atttgaagat cttttttttg actataaaaa 17881 aagtttttgt gcgagagggt atcagttctg atactgcagt aacaatggaa ccttttacag 17941 ggaataatta atcagtaaca atcatgtttt tatatggtgc cagtggtcat gccaaagtga 18001 tcattgatat tttacgagcc ggtcatgaat cgattgaagc gttgtttgat gataatgtgg 18061 aggttacttc tcttcttggt catcccgtat tacgtccgtc ggaagtgcga ggaccactga 18121 tcgtcagtat tggtaataat cggatacgga agaggattgt ggatactttg tccgtggagt 18181 ttggatgtgc tattcatcct ttgtccattg tatccgagct tgctgacatt ggagagggga 18241 gtgtcgtgat gcaagggagt attatacagg tgtgtgctca ggtaggcagg cattgtatta 18301 ttaatacggg tgcctctgtg gatcatgaat gtgtcattga ggattatgtg catatttctc 18361 cacattccac tctctgtgga aatgtattgg tgggggaggg tagctggatt ggcgccggta 18421 ctaccattat tcccggtgtg aagataggaa agtggagtgt gatcggtgct ggttccgtgg 18481 tgactaagga tattccggat catgttttgg cggtgggaaa caaatgtaaa attattaaga 18541 gtatataaaa ttatattatt gatgaacaaa cgaatctggc tttcgcttgc tcacatgggt 18601 ggccgtgagc aagactttat aaaagaggct tttgatacga actgggttgt ccctttggga 18661 cctaacgtgg atgcctttga gcaatctttg gttgaatatt tgcatgaaga ccgctatgta 18721 gtggctttga gtgccggaac ggctgcactt cacttgggct tgattcttct ggatgtgaag 18781 cccggtgatg aagtgatctg ccaaagcttt acttttgctg cctctgccaa tccgatttct 18841 tatctggagg ccaaacctgt ttttgtggac agtgagaagg atacctggaa tatggatccg 18901 gtattgcttg aggaggctat aaaggaccgt ttgcgcaaga cgggtaagct cccgaaggct 18961 attatccctg tccaccttta cggtatgcct gccaagatgg acgagatcat ggatattgcg 19021 ggtcgctatg gtatccccgt attggaggat gccgcggagg ctttgggttc ggaactgaac 19081 ggacggaagt gtggcacatt cggtgaactg gccgctctct ctttcaatgg caacaagatg 19141 atcacgactt ccggtggagg tgctctggtc tgtcgtacgg aagaggaggc ccgacagaca 19201 aagttctatg cgacgcaggc tcgtgatgcc gctccgcatt accagcatac ccatatcggt 19261 tacaactatc ggatgagtaa tatttgtgcg ggtatcggtc gtgggcagat gtttgtcctc 19321 gatgaacata ttgcccgtcg ccgtgccatt cactctttgt atgttgattt gctgaaagat 19381 gtggcgggta ttacggtcat ggagaaccct gattcgcggt ttgcttccaa cttttggctt 19441 acttgtattc tggttgatcc gaagcttgcg ggtaagagtc gtgaggatat ccgtttgagg 19501 ctggactccg agaacataga gacacgtcct ctgtggaagc cgatgcatct tcagcctgtg 19561 ttcacggatg ctccgttcta tgggaatggt acgagtgaga ggttgttcga tatcggcctg 19621 tgtctgcctt cgggacctac actgacagat gaggatatca ggagagtggt ggatacgatt 19681 aggaagatgt agtgaaactg taatattcat tgcaaagaga atcggctgga atattctaaa 19741 tgtttcagcc gattttttat attcagctat atgaaatgaa acatgaagat tatatagata 19801 agatcaatag tttgaccact gccgtcaatc aattcaagga gtcctattct ttgctgaaat 19861 tctcactgga ggcttccgag aaacgtaatg aatccttgca gtttcaagta acccgtcttc 19921 aagatatcat ttgtatcttt actgatgaaa tcagtggttt gcgtgtcgaa gagttcaatc 19981 gcatcagcta tattgagtgc acccgttttg acgttgttga ttatgaggat gaatatatgc 20041 acgaatccgg acaatatcta tttttttgtt gggcgtatgt gcgggcgaag ttcaaatatg 20101 ccgaagaaat aagtaaggat cttgacgccg cgtggtttgt agaacagatt ggacttttgt 20161 atatgtacat atcttaccgt aatgggaaca accaaaatgc atggtctgga agtcagcgat 20221 tatctgatac atgttttcca tga //