Substrate_high_level Substrate_Simple Family Name EC_Number lignin lignin AA1 Laccase / p-diphenol:oxygen oxidoreductase / ferroxidase 1.10.3.2 lignin lignin AA1 ferroxidase 1.10.3.- lignin lignin AA1 Laccase-like multicopper oxidase 1.10.3.- cellulose cellulose AA10 lytic cellulose monooxygenase (C4-dehydrogenating) 1.14.99.56 cellulose cellulose AA10 lytic cellulose monooxygenase (C1-hydroxylating) 1.14.99.54 chitin chitin AA10 lytic chitin monooxygenase 1.14.99.53 xylan xylan AA10 lytic xylan monooxygenase / xylan oxidase (glycosidic bond-cleaving) 1.14.99.- chitin chitin AA11 AA11 proteins are copper-dependent lytic polysaccharide monooxygenases (LPMOs). cleavage of chitin chains with oxidation of C-1 has been demonstrated for a AA11 LPMO from Aspergillus oryzae polyphenol pyrroloquinoline quinone (PQQ, polyphenol) AA12 The pyrroloquinoline quinone-dependent oxidoreductase activity was demonstrated for the CC1G_09525 protein of Coprinopsis cinerea. starch starch AA13 lytic starch monooxygenase / starch oxidase (glycosidic bond-cleaving) 1.14.99.55 xylan xylan AA14 AA14 proteins are copper-dependent lytic polysaccharide monooxygenases (LPMOs).cleavage of xylan with oxidation of C-1 has been demonstrated for two AA14 LPMOs from Trametes coccinea (Pycnoporus coccineus) xylan xylan AA14 lytic xylan monooxygenase / xylan oxidase (glycosidic bond-cleaving) 1.14.99.- cellulose cellulose AA15 lytic cellulose monooxygenase (C1-hydroxylating) 1.14.99.54 chitin chitin AA15 lytic chitin monooxygenase 1.14.99.53 cellulose cellulose AA16 Lytic cellulose monooxygenase (C1-hydroxylating) 1.14.99.54 pectin pectin AA17 Lytic polygalacturonic acid monooxygenase (C4-hydroxylating) 1.14.99.- pectin pectin AA17 Lytic polygalacturonic acid monooxygenase (C4-hydroxylating) 1.14.99.- lignin lignin AA2 cytochrome-c peroxidase 1.11.1.5 lignin lignin AA2 versatile peroxidase 1.11.1.16 lignin lignin AA2 lignin peroxidase 1.11.1.14 lignin lignin AA2 manganese peroxidase 1.11.1.13 lignin lignin AA2 ascorbate peroxidase 1.11.1.11 lignin lignin AA2 peroxidase 1.11.1.- cellulose cellulose AA3 cellobiose dehydrogenase 1.1.99.18 lignin lignin AA3 aryl alcohol oxidase 1.1.3.7 lignin lignin AA3 glucose 1-oxidase 1.1.3.4 lignin lignin AA3 alcohol oxidase 1.1.3.13 lignin lignin AA3 pyranose oxidase 1.1.3.10 lignin lignin AA4 vanillyl-alcohol oxidase 1.1.3.38 lignin lignin AA5 glyoxal oxidase 1.2.3.15 lignin lignin AA5 galactose oxidase 1.1.3.9 lignin lignin AA5 alcohol oxidase 1.1.3.13 lignin lignin AA5 Oxidase with oxygen as acceptor 1.1.3.- lignin lignin AA5 raffinose oxidase 1.1.3.- lignin lignin AA6 1,4-benzoquinone reductase 1.6.5.6 glucooligosaccharide glucooligosaccharide AA7 glucooligosaccharide oxidase 1.1.3.- chitooligosaccharide chitooligosaccharide AA7 chitooligosaccharide oxidase 1.1.3.- cellooligosaccharide cellooligosaccharide AA7 cellooligosaccharide dehydrogenase 1.1.99.- lignin lignin AA8 Iron reductase domain cellulose cellulose AA9 lytic cellulose monooxygenase (C4-dehydrogenating) 1.14.99.56 cellulose cellulose AA9 lytic cellulose monooxygenase (C1-hydroxylating) 1.14.99.54 cellulose cellulose AA9 AA9 (formerly GH61) proteins are copper-dependent lytic polysaccharide monooxygenases (LPMOs).cleavage of cellulose chains with oxidation of carbons C1 and/or C4 and C-6) ulvan ulvan CBM90 Modules of approx 110 residues appended to PL24 and PL28 ulvan lyases; ulvan-binding function demonstrated for the CBM90 module of PL28 ulvan lyase from Nonlabens ulvanivorans xylan xylan CBM91 Binding to xylans (birchwood and oat spelt) cellulose, chitin cellulose, chitin CBM1 Modules of approx. 40 residues found almost exclusively in fungi. The cellulose-binding function has been demonstrated in many cases, and appears to be mediated by three aromatic residues separated by about 10.4 angstrom and which form a flat surface. The only non-fungal occurence of CBM1 is in an algal non-hydrolytic polysaccharide-binding protein which is composed of four repeated CBM1 modules. Binding to chitin has been demonstrated in one case. cellulose cellulose CBM10 Modules of approx. 50 residues. The cellulose-binding function has been demonstrated in one case. beta-glucan cellulose, mixed linked glucan CBM11 Modules of approx. 180-200 residues. The CBM11 of Clotridium thermocellum Cel26A-Cel5E has been shown to bind both beta-1,4-glucan and beta-1,3-1,4-mixed linked glucans. chitin chitin CBM12 Modules of approx. 40-60 residues. The majority of these modules is found among chitinases where the function is chitin-binding. Distantly related to the CBM5 family. xylan plant lectin, xylan CBM13 Modules of approx. 150 residues which always appear as a threefold internal repeat. The only apparent exception to this, xylanase II of Actinomadura sp. FC7 (GenBank U08894), is in fact not completely sequenced. These modules were first identified in several plant lectins such as ricin or agglutinin of Ricinus communis which bind galactose residues. The three-dimensional structure of a plant lectin has been determined and displays a pseudo-threefold symmetry in accord with the observed sequence threefold repeat. These modules have since been found in a number of other proteins of various functions including glycoside hydrolases and glycosyltransferases. While in the plant lectins this module binds mannose, binding to xylan has been demonstrated in the Streptomyces lividans xylanase A and arabinofuranosidase B. Binding to GalNAc has been shown for the corresponding module of GalNAc transferase 4. For the other proteins, the binding specificity of these modules has not been established. The pseudo three-fold symmetry of the CBM13 module has now been confirmed in the 3-D structure of the intact, two-domain, xylanase of Streptomyces olivaceoviridis. chitin chitin CBM14 Modules of approx. 70 residues. The chitin-binding function has been demonstrated in several cases. These modules are found attached to a number of chitinase catalytic domains, but also in non-catalytic proteins either in isolation or as multiple repeats xylan xylan and xylooligosaccharide CBM15 Binding to xylan and xylooligosaccharides has been demonstrated in the case of Xyn10C of Cellvibrio mixtus. cellulose, glucomannan cellulose and glucomannan CBM16 Carbohydrate-binding module 16. Binding to cellulose and glucomannan demonstrated [B. Bae et al (2008) J Biol Chem. 283:12415-25 (PMID: 18025086)] cellulose amorphous cellulose, cellooligosaccharides and derivatized cellulose CBM17 Modules of approx. 200 residues. Binding to amorphous cellulose, cellooligosaccharides and derivatized cellulose has been demonstrated. chitin chitin CBM18 Modules of approx. 40 residues. The chitin-binding function has been demonstrated in many cases. These modules are found attached to a number of chitinase catalytic domains, but also in non-catalytic proteins either in isolation or as multiple repeats. chitin chitin CBM19 Modules of 60-70 residues with chitin-binding function. cellulose, chitin, xylan cellulose, chitin, xylan CBM2 Modules of approx. 100 residues and which are found in a large number of bacterial enzymes. The cellulose-binding function has been demonstrated in many cases. Several of these modules have been shown to also bind chitin or xylan. starch granular starch, cyclodextrin CBM20 The granular starch-binding function has been demonstrated in several cases. Interact strongly with cyclodextrins. Often designated as starch-binding domains (SBD). starch granular starch CBM21 Modules of approx. 100 residues. The granular starch-binding function has been demonstrated in one case. Sometimes designated as starch-binding domains (SBD). xylan, beta-glucan xylan,1,3/beta-1,4-glucans CBM22 A xylan binding function has been demonstrated in several cases and affinity with mixed beta-1,3/beta-1,4-glucans in one. In several cases a thermostabilizing effect has also been seen. beta-mannan mannan CBM23 Mannan-binding function demonstrated in one case. beta-glucan mutan CBM24 alpha-1,3-glucan (mutan)-binding function demonstrated in two cases (PMID:10636904) starch starch CBM25 Starch-binding function demonstrated in one case. starch starch CBM26 Starch-binding function demonstrated in two cases. beta-mannan mannan CBM27 Mannan-binding function demonstrated in two cases cellulose non-crystalline cellulose, cellooligosaccharides, and beta-(1,3)(1,4)-glucans CBM28 The module from the endo-1,4-glucanase of Bacillus sp. 1139 binds to non-crystalline cellulose, cellooligosaccharides, and beta-(1,3)(1,4)-glucans beta-mannan mannan,glucomannan CBM29 Binding to mannan/glucomannan has been demonstrated. cellulose, chitin cellulose,chitin CBM3 Modules of approx. 150 residues found in bacterial enzymes. The cellulose-binding function has been demonstrated in many cases. In one instance binding to chitin has been reported. cellulose cellulose CBM30 Binding to cellulose has been demonstrated for the N-terminal module of Fibrobacter succinogenes CelF. xylan beta-1,3-xylan CBM31 Binding to beta-1,3-xylan has been demonstrated for the C-terminal module of the beta-1,3-xylanase of Alcaligenes sp. XY234. host glycan galactose, lactose, LacNAc CBM32 Binding to galactose and lactose has been demonstrated for the module of Micromonospora viridifaciens sialidase (PMID: 16239725). Binding to polygalacturonic acid has been shown for a Yersinia member (PMID: 17292916). Binding to LacNAc (beta-D-galactosyl-1,4-beta-D-N-acetylglucosamine) has been shown for an N-acetylglucosaminidase from Clostridium perfingens (PMID: 16990278). cellulose, chitin cellulose, chitin CBM33 Copper-dependent lytic polysaccharide monooxygenases now reclassified in family AA10 starch granular starch CBM34 Modules of approx. 120 residues. Granular starch-binding function has been demonstrated in the case of Thermoactinomyces vulgaris R-47 alpha-amylase 1 (TVAI). xylan, beta-mannan, beta-galactan xylan,decorated soluble mannan and mannooligosaccharide,beta-galactan CBM35 Modules of approx. 130 residues. A module that is conserved in three Cellvibrio xylan-degrading enzymes binds to xylan and the interaction is calcium dependent, while a module from a Cellvibrio mannanase binds to decorated soluble mannans and mannooligosaccharides. A module in a Phanerochaete chrysosporium galactan 1,3-beta-galactosidase binds to beta-galactan. xylan xylan and xylooligosaccharide CBM36 Modules of approx. 120-130 residues displaying structural similarities to CBM6 modules. The only CBM36 currently characterised, that from Paenbacillus polymyxa xylanase 43A, shows calcium-dependent binding of xylans and xylooligosaccharides. X-ray crystallography shows that there is a direct interaction between calcium and ligand. xylan, chitin, cellulose xylan, chitin, microcrystalline and phosphoric-acid swollen cellulose, as well as more heterogeneous substrates, such as alfalfa cell walls, banana stem and wheat straw. CBM37 Modules of approx. 100 residues, conserved in numerous R. albus polysaccharide-degrading enzymes and other proteins from this bacterium. Several members of CBM37 have been shown to exhibit rather broad binding specificity to xylan, chitin, microcrystalline and phosphoric-acid swollen cellulose, as well as more heterogeneous substrates, such as alfalfa cell walls, banana stem and wheat straw. fructan inulin CBM38 The inulin-binding function has been demonstrated in the case of the cycloinulo-oligosaccharide fructanotransferase from Paenibacillus macerans (Bacillus macerans) by Lee et al. (2004) FEMS Microbiol Lett 234:105-10. (PMID:15109727). beta-glucan,lipopolysaccharide beta-1,3-glucan,lipopolysaccharide and lipoteichoic acid CBM39 Modules generally found at the N-terminus of a GH16 module (itself frequently lacking a catalytic machinery) and more seldomly in isolation. The beta-1,3-glucan binding function has been demonstrated, along with binding to lipopolysaccharide and lipoteichoic acid. xylan, beta-glucan xylan, beta-1,3-glucan, beta-1,3-1,4-glucan, beta-1,6-glucan and amorphous cellulose CBM4 Modules of approx. 150 residues found in bacterial enzymes. Binding of these modules has been demonstrated with xylan, beta-1,3-glucan, beta-1,3-1,4-glucan, beta-1,6-glucan and amorphous cellulose but not with crystalline cellulose. sialic acid sialic acid CBM40 Modules of approx. 200 residues, found at the N-terminus of GH33 sialidases. Can also be found inserted in the beta-propeller of GH33 sialidases. The sialic acid binding function has been demonstrated for the N-terminal CBM40 of Vibrio cholerae sialidase (Moustafa et al. (2004) J Biol Chem 279:40819-26) (PMID: 15226294). beta-glucan alpha-glucans amylose, amylopectin, pullulan, and oligosaccharide fragments derived from these polysaccharides CBM41 Modules of approx. 100 residues found in primarily in bacterial pullulanases. The N-terminal module from Thermotoga maritima Pul13 has been shown to bind to the alpha-glucans amylose, amylopectin, pullulan, and oligosaccharide fragments derived from these polysaccharides (Lammerts van Bueren et al. (2004) Biochemistry 43:15633-42) (PMID: 15581376). xylan arabinoxylan CBM42 Modules of approx. 160 residues found mostly at the C-terminus of GH54 catalytic domains. Binding to arabinofuranose (present in arabinoxylan) has been demonstrated. beta-glucan beta-1,3-glucan CBM43 Modules of approx. 90-100 residues found at the C-terminus of GH17 or GH72 enzymatic modules and also sometimes isolated. CBM43 modules sometimes carry a C-terminal membrane anchor. The beta-1,3-glucan binding function has been demonstrated with the olive pollen protein Ole e 10. cellulose, xyloglucan cellulose and xyloglucan CBM44 The C-terminal CBM44 module of the Clostridium thermocellum enzyme has been demonstrated to bind equally well cellulose and xyloglucan starch starch CBM45 Modules of approx. 100 residues, found at the N-terminus of plastidial alpha-amylases and of alpha-glucan, water dikinases. Starch-binding activity demonstrated in the case of potato alpha-glucan, water dikinase. cellulose cellulose CBM46 Modules of approx. 100 residues, found at the C-terminus of several GH5 cellulases. Cellulose-binding function demonstrated in one case. fucose fucose CBM47 Modules of approx 150 residues. Fucose-binding activity demonstrated glycogen glycogen CBM48 Modules of approx. 100 residues with glycogen-binding function, appended to GH13 modules. Also found in the beta subunit (glycogen-binding) of AMP-activated protein kinases (AMPK) cellulose crystalline cellulose CBM49 Modules of approx. 100 residues found at the C-terminus of plant GH9 enzymes. Distantly related to CBM2 modules. Binding to crystalline cellulose demonstrated in the case of Solanum lycopersicum Cel8 enzyme (SlCel9C1). chitin chitin CBM5 Modules of approx. 60 residues found in bacterial enzymes. Chitin-binding described in several cases. Distantly related to the CBM12 family. chitin, peptidoglycan chitin or peptidoglycan CBM50 Modules of approx. 50 residues found attached to various enzymes from families GH18, GH19, GH23, GH24, GH25 and GH73, i.e. enzymes cleaving either chitin or peptidoglycan. Binding to chitopentaose demonstrated in the case of Pteris ryukyuensis chitinase A [Ohnuma T et al. (2008) J. Biol. Chem. 283:5178-87 (PMID: 18083709)]. CBM50 modules are also found in a multitude of other enzymes targeting the petidoglycan such as peptidases and amidases. These enzymes are not reported in the list below. host glycan galactose and to blood group A/B-antigens CBM51 Modules of approx. 150 residues found attached to various enzymes from families GH2, GH27, GH31, GH95, GH98 and GH101 . Binding to galactose and to blood group A/B-antigens demonstrated in the case of C. perfringens GH95CBM51 and GH98CBM51 respectively [Gregg KJ et al. (2008) J. Biol. Chem. 283:12604-13 PMID: 18292090]. beta-glucan beta-1,3-glucan CBM52 Modules of approx. 60 residues attached to a few GH81 enzymes but present in other proteins. Binding to beta-1,3-glucan demonstrated for Schizosaccharomyces pombe 972h- endo-1,3-beta-glucanase Eng1 [Martin-Quadrado et al., Mol. Microbiol. (2008) 69:188-200 PMID:18466295] starch starch CBM53 Starch-binding function demonstrated by Valdez et al. (2008) [PMID: 18260645] xylan, beta-glucan, chitin xylan, yeast cell wall glucan and chitin CBM54 Binding to xylan, yeast cell wall glucan and chitin shown in Dvortsov et al., Microbiology UK (2009) in press. chitin chitin CBM55 Binding to chitin demonstrated in the case of the CBM55 of Entamoeba histolytica chitinase (Van Dellen et al. (2002) Infect Immun. 70:3259-3263,PMID: 12011021). beta-glucan beta-1,3-glucan CBM56 beta-1,3-glucan binding function demonstrated by Yamamoto et al. (1998) FEBS Letters 433:41-43 [PMID: 9738929] glycosidases glycosidases CBM57 Created from reading Schallus et al (2008) Mol Biol Cell. 19:3404-3414 [PMID: 18524852] and finding related domains attached to various glycosidases. starch maltoheptaose CBM58 The CBM58 module of the Bacteroides thetaiotaomicron SusG protein has been shown to bind maltoheptaose mannan, xylan, and cellulose mannan, xylan, and cellulose CBM59 Binding to mannan, xylan, and cellulose demonstrated for the CBM59 of ManF-X10 xylanase from an environmental genomic DNA library (Li et al. (2009) World Journal of Microbiology and Biotechnology 25:2071-2078,doi:10.1007/s11274-009-0111-6) beta-glucan, xylan, cellulose amorphous cellulose, beta-1,4-xylan,beta-1,3-glucan, beta-1,3-1,4-glucan, and beta-1,4-glucan CBM6 Modules of approx. 120 residues. The cellulose-binding function has been demonstrated in one case on amorphous cellulose and beta-1,4-xylan. Some of these modules also bind beta-1,3-glucan, beta-1,3-1,4-glucan, and beta-1,4-glucan. xylan xylan CBM60 Modules of approx 120 residues usually found appended to xylanases. The xylan-binding function and the relatedness (circular permutation) to family CBM36 has been demonstrated [PMID: 20659893]. beta-galactan beta-1,4-galactan CBM61 Modules of approx. 150 residues found appended to GH16, GH30, GH31, GH43, GH53 and GH66 catalytic domains. A beta-1,4-galactan binding function has been demonstrated for the CBM61 of Thermotoga maritima GH53 galactanase [PMID: 20826814]. xyloglucan, arabinogalactan and galactomannan xyloglucan, arabinogalactan and galactomannan CBM62 The CBM62 module of Clostridium thermocellum Cthe_2193 protein binds galactose moieties found on xyloglucan, arabinogalactan and galactomannan. cellulose cellulose CBM63 The CBM63 module of Bacillus subtilis expansin EXLX1 has been shown to bind cellulose. cellulose cellulose CBM64 Module found at C-term of several Spirochaeta thermophila proteins. Binding to cellulose shown by Angelov, Loderer, Pompei Liebl (2011) AEM, 77:5483-5489 [PMID - 21685171] xyloglucan xyloglucan CBM65 CBM65A and CBM65B, derived from Eubacterium cellulosolvens endoglucanase EcCel5A, bind to a range of beta-glucans but, uniquely, display significant preference for xyloglucan fructan fructan CBM66 The CBM66 module, derived from the Bacillus subtilis exo-acting beta-fructosidase SacC, targets the terminal fructoside residue of fructans. rhamnose L-rhamnose CBM67 Fujimoto et al. [PMID : 23486481] disclosed the L-rhamnose binding activity and 3-D structure of the CBM67 of Streptomyces avermitilis alpha-L-rhamnosidase (SaRha78A) starch maltotriose and maltotetraose CBM68 Binding to maltotriose and maltotetraose shown for the pullulanase of Anoxybacillus sp. LM18-11. Binding function derived from crystal structure and deletion of the CBM, which showed reduced specific activity and increased Km value compared to the wild type enzyme. starch starch CBM69 starch-binding function demonstrated in one case, distantly related to families CBM20 and CBM48 host glycan hyaluronan CBM70 The hyaluronan-specific binding function of the N-terminal CBM70 module of Streptococcus pneumoniae hyaluronate lyase has been demonstrated. host glycan lactose and LacNAc CBM71 The two CBM71s of S. pneumoniae BgaA bind lactose and LacNAc. beta-glucan, xylan, and beta-mannan broad spectrum of polysaccharides including soluble and insoluble cellulose, beta-1,3/1,4-mixed linked glucans, xylan, and beta-mannan CBM72 Modules of 130-180 residues found at the C-terminus glycoside hydrolases from various families, sometimes as tandem repeats. The CBM72 found on an endoglucanase from an uncultivated microorganism was found to bind a broad spectrum of polysaccharides including soluble and insoluble cellulose, beta-1,3/1,4-mixed linked glucans, xylan, and beta-mannan [PMID=26765840]. chitin chitin CBM73 Modules of approx 65 residues found on various enzymes active of chitin. Chitin-binding function demonstrated for the Cellvibrio japonicus CjLPMO10A protein. starch starch CBM74 Modules of approx. 300 residues appended to several alpha-amylases. The starch-binding function has been demonstrated for the CBM74 appended to the GH13 alpha-amylase of Microbacterium aureum B8.A xyloglucan xyloglucan CBM75 Modules of 290 residues appended to GH43_16 enzymes. So far found exclusively in Ruminococci. The xyloglucan-binding function was demonstrated for the R. flavefaciens protein. xyloglucan, glucomannan, and beta-glucan xyloglucan, glucomannan, and barley beta-glucan CBM76 Modules of approx. 170 residues appended to GH44 enzymes. So far found exclusively in Ruminococci. Broad specificity binding to beta-glucans demontsrated for the R. flavefaciens module, which binds xyloglucan, glucomannan, and barley beta-glucan. pectin various CBM77 Pectin binding modules of approx. 110 residues. The Ruminococcus flavefaciens CBM77 was shown to bind various pectins of low degree of esterification. beta-glucan beta-1,4-glucans CBM78 Modules of approx. 150 residues appended to the C-terminus of GH5 and GH26 enzymes. So far found exclusively in Ruminococcal enzymes. The R. flavefaciens module has been shown to bind decorated beta-1,4-glucans with a preference for xyloglucan. beta-glucan beta-glucans CBM79 Modules of approx. 130 residues found so far only in ruminococcal proteins. Binding to various beta-glucans was shown for the R. flavefaciens GH9 enzyme. cellulose cellulose CBM8 The cellulose-binding module from a cellulase of the slime mold Dictyostelium discoideum has been experimentally shown to bind cellulose. beta-glucan, beta-mannan beta-glycans (xyloglucan, glucomannan, galactomannan, barley beta-glucan) CBM80 Modules of approx. 90 residues found so far only in ruminococcal enzymes of families GH5 or GH26. Broad specificity for beta-glycans (xyloglucan, glucomannan, galactomannan, barley beta-glucan). beta-glucan beta-1,4-, beta-1,3,-glucans, xyloglucan, avicel and cellooligosaccharides CBM81 Small family of modules of approx. 100 residues, appended to GH5_2 enzymes. So far found exclusively in a few gammaproteobacteria. The CBM81 from an uncultivated species was shown to have binding affinity for beta-1,4-, beta-1,3,-glucans, xyloglucan, avicel and cellooligosaccharides. starch starch CBM82 The boundaries, structure and starch-binding function of the CBM82 module of Eubacterium rectale Amy13K have been reported by Cockburn and coworkers in Molec. Microbiol. (2017) (PMID=29139580) starch starch CBM83 The boundaries, structure and starch-binding function of the CBM83 module of Eubacterium rectale Amy13K have been reported by Cockburn and coworkers in Molec. Microbiol. (2017) (PMID=29139580) xanthan xanthan CBM84 Modules of approx. 140 aminoacids appended to enzymes of different families of CAZymes. A xanthan-binding function was reported for the GH9 xanthanase of Paenibacillus nanensis by Moroz et al. ACS Catal., 2018, 8 (7), pp 6021-6034. cellulose, xylan, beta-glucan, beta-mannan glycans (cellulose, glucuronoxylan, b-1,3-1,4-glucan and glucomannan) CBM85 Created after Fredriksen et al. (2019) PMID=30635385; binds to a broad range of glycans (cellulose, glucuronoxylan, b-1,3-1,4-glucan and glucomannan) xylan xylan CBM86 Created after the report of an activity [Leth et al. (2018), Nat. Microbiol, PMID:29610517] and a structure [Leth et al. (2019), FEBS J, PMID:31693302] of a xylan-binding module in the Xyn10A protein of Roseburia intestinalis L1-82. galactosaminogalactan galactosaminogalactan CBM87 Binding to alpha-1,4-N-acetylgalactosamine-rich regions of galactosaminogalactan galactoxyloglucan and galactomannan galactoxyloglucan and galactomannan CBM88 Binding to terminal galactose in galactoxyloglucan and galactomannan xylan xylan CBM89 cellulose cellulose CBM9 Modules of approx. 170 residues found so far only in xylanases. The cellulose-binding function has been demonstrated in one case. ulvan ulvan CBM90 Modules of approx 110 residues appended to PL24 and PL28 ulvan lyases; ulvan-binding function demonstrated for the CBM90 module of PL28 ulvan lyase from Nonlabens ulvanivorans xylan xylan CBM91 Created after Ito et al. 2022 [DOI=10.5458/jag.jag.JAG-2022_0001] who demonstrated the xylan binding activity in the PxXyl43A protein (Paenibacillus xylaniclasticus TW1) Modules of ~200aa, frequently associated with GH43 notably. carrageenan carrageenan CBM92 Carrageenan binding activity was reported for the module of Cgk16A protein in Wenyingzhuangia sp. OF219 (AST13124.1) [PubMed=35830544] uric acid 5-Hydroxyisourate (uric acid) GH1 hydroxyisourate hydrolase 3.-.-.- beta-glucan beta-glucan GH1 beta-glycosidase 3.2.1.- polyphenol rutin (polyphenol) GH1 beta-rutinosidase /alpha-L-rhamnose-(1,6)-beta-D-glucosidase 3.2.1.- alkaloid strictosidine (monoterpene indole alkaloids) GH1 strictosidine beta-glucosidase 3.2.1.105 human milk polysaccharide lactose in milk, phlorizin (polyphenols) in fruit GH1 lactase 3.2.1.108 polyphenol amygdalin (cyanogenic glycosides) GH1 amygdalin beta-glucosidase 3.2.1.117 polyphenol prunasin (cyanogenic glycosides) GH1 prunasin beta-glucosidase 3.2.1.118 polyphenol vicianin (cyanogenic glycosides) GH1 vicianin hydrolase 3.2.1.119 alkaloid Raucaffricine (glucoalkaloid) GH1 raucaffricine beta-glucosidase 3.2.1.125 polyphenol glucosinolates (sulfur-containing phytochemicals) GH1 thioglucosidase 3.2.1.147 polyphenol β-primeverosides (tea plant phytochemicals) GH1 beta-primeverosidase 3.2.1.149 polyphenol Daidzin and genistin, Furcatin (polyphenol) GH1 isoflavonoid 7-O-beta-apiosyl-beta-glucosidase 3.2.1.161 polyphenol abscisic acid (plant) GH1 ABA-specific beta-glucosidase 3.2.1.175 polyphenol DIMBOA glucoside (polyphenol) GH1 DIMBOA beta-glucosidase 3.2.1.182 polyphenol Furostanol (polyphenol) GH1 protodioscin 26-O-β-D-glucosidase 3.2.1.186 beta-glucan beta-glucoside GH1 beta-glucosidase 3.2.1.21 beta-galactan beta-galactoside GH1 beta-galactosidase 3.2.1.23 beta-mannan beta-mannoside GH1 beta-mannosidase 3.2.1.25 beta-glucuronan beta-glucuronoside GH1 beta-glucuronidase 3.2.1.31 xylan beta-glucoside, beta-xyloside GH1 beta-xylosidase 3.2.1.37 beta-fucosides beta-fucosides GH1 beta-D-fucosidase 3.2.1.38 polyphenol phlorizin (polyphenols) in fruit GH1 phlorizin hydrolase 3.2.1.62 beta-glucan beta-glucoside GH1 exo-beta-1,4-glucanase 3.2.1.74 beta-galactan 6-phospho-beta-galactoside GH1 6-phospho-beta-galactosidase 3.2.1.85 beta-glucan 6-phospho-beta-glucoside GH1 6-phospho-beta-glucosidase 3.2.1.86 xylan xylan GH10 xylan endotransglycosylase 2.4.2.- alkaloid alpha-tomatine (glycoalkaloids) GH10 tomatinase 3.2.1.- xylan arabinoxylan GH10 [retaining] arabinoxylan-specific endo-beta-1,4-xylanase 3.2.1.- xylan xylan GH10 endo-1,3-beta-xylanase 3.2.1.32 beta-glucan cellulose, xylan, beta-1,4-glucan GH10 endo-beta-1,4-glucanase 3.2.1.4 xylan xylan GH10 endo-1,4-beta-xylanase 3.2.1.8 sucrose sucrose GH100 alkaline and neutral invertase 3.2.1.26 host glycan mucin GH101 endo-alpha-N-acetylgalactosaminidase 3.2.1.97 peptidoglycan peptidoglycan GH102 peptidoglycan lytic transglycosylase 3.2.1.- peptidoglycan peptidoglycan GH103 peptidoglycan lytic transglycosylase 3.2.1.- peptidoglycan peptidoglycan GH104 peptidoglycan lytic transglycosylase 3.2.1.- ulvan ulvan GH105 d-4,5-unsaturated beta-glucuronyl hydrolase 3.2.1.- pectin pectin GH105 d-4,5-unsaturated alpha-galacturonidase 3.2.1.- pectin pectin (rhamnogalacturonan I) GH105 unsaturated rhamnogalacturonyl hydrolase 3.2.1.172 pectin pectin (rhamnogalacturonan I) GH106 rhamnogalacturonan alpha-L-rhamnohydrolase 3.2.1.174 pectin pectin (rhamnogalacturonan II) GH106 alpha-L-rhamnosidase 3.2.1.40 fucoidan fucoidan (brown algae) GH107 endo-alpha-1,4-L-fucanase 3.2.1.212 peptidoglycan peptidoglycan GH108 N-acetylmuramidase 3.2.1.17 host glycan mucin-type O-glycans GH109 alpha-N-acetylgalactosaminidase 3.2.1.49 host glycan mucin-type O-glycans GH109 beta-N-acetylhexosaminidase 3.2.1.52 xylan xylan GH11 exo-1,4-beta-xylosidase 3.2.1.- xylan xylan GH11 endo-beta-1,4-xylanase 3.2.1.8 host glycan blood group B substances, host glycans GH110 alpha-1,3-galactosidase 3.2.1.- host glycan blood group B substances, host glycans GH110 alpha-galactosidase 3.2.1.22 host glycan keratan, host glycans GH111 keratan sulfate hydrolase (endo-beta-N-acetylglucosaminidase) 3.2.1.- human milk polysaccharide human milk oligosaccharides, host glycans GH112 lacto-N-biose phosphorylase or galacto-N-biose phosphorylase 2.4.1.211 human milk polysaccharide human milk oligosaccharides, host glycans GH112 D-galactosyl-beta-1,4-L-rhamnose phosphorylase 2.4.1.247 beta-mannan beta-mannan GH113 beta-mannanase 3.2.1.78 alpha-mannan galactosaminogalactan (fungal exopolysaccharide) GH114 endo-alpha-1,4-polygalactosaminidase 3.2.1.109 arabinogalactan protein arabinogalactan GH115 alpha-(4-O-methyl)-glucuronidase 3.2.1.- xylan glucuronoxylan GH115 xylan alpha-1,2-glucuronidase 3.2.1.131 exo-polysaccharide human bile acid, archaea exo-polysaccharide (EPS) GH116 beta-glucosidase 3.2.1.21 exo-polysaccharide archaea exo-polysaccharide (EPS) GH116 beta-xylosidase 3.2.1.37 host glycan lipid glucosylceramide (host cell surface) GH116 acid beta-glucosidase/beta-glucosylceramidase 3.2.1.45 exo-polysaccharide archaea exo-polysaccharide (EPS) GH116 beta-N-acetylglucosaminidase 3.2.1.52 agarose neoagarose (marine algae) GH117 beta-D-galactofuranosidase 3.2.1.146 agarose neoagarose (marine algae) GH117 alpha-neoagaro-oligosaccharide hydrolase 3.2.1.159 agarose agarose (marine algae) GH118 beta-agarase 3.2.1.81 starch starch GH119 alpha-amylase 3.2.1.1 xyloglucan xyloglucan GH12 xyloglucan endotransglycosylase 2.4.1.207 xyloglucan xyloglucan GH12 xyloglucan hydrolase 3.2.1.151 cellulose cellulose, beta-glucan GH12 endoglucanase 3.2.1.4 beta-glucan mixed-linkage glucan GH12 beta-1,3-1,4-glucanase 3.2.1.73 xylan xylan GH120 beta-xylosidase 3.2.1.37 arabinan hydroxyproline-rich glyoproteins (arabinan in extensin and lectin) GH121 beta-L-arabinobiosidase 3.2.1.- starch starch GH122 alpha-glucosidase 3.2.1.20 host glycan glycosphingolipid (host glycan) GH123 glycosphingolipid beta-N-acetylgalactosaminidase 3.2.1.- host glycan glycosphingolipid (host glycan) GH123 beta-N-acetylgalactosaminidase 3.2.1.53 cellulose cellulose GH124 endoglucanase 3.2.1.4 alpha-mannan alpha-mannan, plant N-glycan GH125 exo-alpha-1,6-mannosidase 3.2.1.- alpha-glucan starch, glycogen, and malto-oligosaccharides GH126 alpha-amylase 3.2.1.- pectin pectin (rhamnogalacturonan II) GH127 3-C-carboxy-5-deoxy-L-xylose (aceric acid) hydrolase 3.2.1.- carrageenan carrageenan (marine algae) GH127 alpha-1,3-(3,6)-anhydro-D-galactosidase 3.2.1.- arabinogalactan protein arabinogalactan proteins GH127 beta-L-arabinofuranosidase 3.2.1.185 beta-glucan beta-1,3-glucan (bacteria, fungi, plant, algae) GH128 beta-1,3-glucosidase 3.2.1.- beta-glucan beta-1,3-glucan (bacteria, fungi, plant, algae) GH128 beta-1,3-glucanase 3.2.1.39 carrageenan carrageenan (marine algae) GH129 alpha-1,3-(3,6)-anhydro-D-galactosidase 3.2.1.- host glycan mucin-type O-glycans GH129 alpha-N-acetylgalactosaminidase 3.2.1.49 alpha-glucan starch, glycogen, and malto-oligosaccharides GH13 oligosaccharide alpha-4-glucosyltransferase 2.4.1.161 alpha-glucan starch, glycogen, and malto-oligosaccharides GH13 branching enzyme 2.4.1.18 alpha-glucan cyclodextrin (α-1,4 glycosidic glucan from starch degradation) GH13 cyclomaltodextrin glucanotransferase 2.4.1.19 glycogen glycogen GH13 4-alpha-glucanotransferase 2.4.1.25 sucrose sucrose GH13 [retaining] sucrose 6(F)-phosphate phosphorylase 2.4.1.329 glucosylglycerate glucosylglycerate GH13 Glucosylglycerate phosphorylase 2.4.1.352 glucosylglycerol glucosylglycerol GH13 [retaining] glucosylglycerol phosphorylase 2.4.1.359 sucrose Sucrose GH13 amylosucrase 2.4.1.4 sucrose Sucrose GH13 sucrose phosphorylase 2.4.1.7 starch starch, glycogen, and malto-oligosaccharides GH13 alpha-1,4-glucan: phosphate alpha-maltosyltransferase 2.4.99.16 starch starch GH13 maltopentaose-forming alpha-amylase 3.2.1.- starch starch, glycogen, and malto-oligosaccharides GH13 alpha-amylase 3.2.1.1 starch starch, glycogen, and malto-oligosaccharides GH13 [retaining] alpha-amylase 3.2.1.1 starch amylopectin (starch) GH13 oligo-alpha-glucosidase 3.2.1.10 starch starch GH13 maltotriose-forming alpha-amylase 3.2.1.116 starch starch GH13 maltogenic amylase 3.2.1.133 starch pullulan (starch degradation by fungi) GH13 neopullulanase 3.2.1.135 starch starch GH13 malto-oligosyltrehalose trehalohydrolase 3.2.1.141 starch starch GH13 alpha-glucosidase 3.2.1.20 starch maltooligosaccharides GH13 amylo-alpha-1,6-glucosidase 3.2.1.33 starch pullulan (starch degradation by fungi) GH13 pullulanase 3.2.1.41 sucrose sucrose GH13 [retaining] sucrose alpha-glucosidase 3.2.1.48 starch cyclomaltodextrins GH13 cyclomaltodextrinase 3.2.1.54 starch starch GH13 maltotetraose-forming alpha-amylase 3.2.1.60 starch starch, glycogen, and malto-oligosaccharides GH13 isoamylase 3.2.1.68 starch starch, glycogen, and α-1,6 glucan GH13 glucodextranase 3.2.1.70 trehalose trehalose GH13 trehalose-6-phosphate hydrolase 3.2.1.93 starch starch, glycogen, and malto-oligosaccharides GH13 maltohexaose-forming alpha-amylase 3.2.1.98 sucrose sucrose GH13 isomaltulose synthase 5.4.99.11 starch starch GH13 malto-oligosyltrehalose synthase 5.4.99.15 starch maltose GH13 trehalose synthase 5.4.99.16 sucrose sucrose 6(F)-phosphate GH13 amino acid transporter beta-mannan mannooligosaccharides GH130 beta-1,2-oligomannan phosphorylase 2.4.1.- beta-mannan beta-mannan GH130 beta-1,2-mannobiose phosphorylase 2.4.1.- beta-mannan beta-mannan GH130 beta-1,4-mannosylglucose phosphorylase 2.4.1.281 beta-mannan beta-mannan GH130 beta-1,4-mannooligosaccharide phosphorylase 2.4.1.319 beta-mannan beta-mannan GH130 β-1,2-oligomannan phosphorylase 2.4.1.340 beta-mannan beta-mannan GH130 β-1,2-mannobiose phosphorylase 2.4.1.339 beta-mannan beta-mannan GH130 beta-1,4-mannosyl-N-acetyl-glucosamine phosphorylase 2.4.1.320 beta-mannan beta-mannan GH130 beta-1,2-mannosidase 3.2.1.- beta-glucan beta-glucans, including laminarin, curdlan, pachyman, lichenan, pustulan, and cellulosic derivatives GH131 broad specificity exo-beta-1,3/1,6-glucanase with endo-beta-1,4-glucanase activity 3.2.1.- beta-glucan beta-1,3-glucan (fungi) GH132 beta-1,3-glucosidase 3.2.1.- glycogen glycogen GH133 amylo-alpha-1,6-glucosidase 3.2.1.33 beta-mannan beta-mannan GH134 endo-beta-1,4-mannanase 3.2.1.78 alpha-galactan exopolysaccharide galactosaminogalactan (fungal GAG) GH135 alpha-1,4-galactosaminogalactan hydrolase 3.2.1.- human milk polysaccharide human milk oligosaccharides GH136 Lacto-N-biosidase (Lewis antigen a/b specificity) 3.2.1.- human milk polysaccharide human milk oligosaccharides GH136 lacto-N-biosidase 3.2.1.140 pectin pectin (rhamnogalacturonan II) GH137 beta-L-arabinofuranosidase 3.2.1.185 pectin pectin (rhamnogalacturonan II) GH138 rhamnogalacturonan alpha-1,2-galacturonohydrolase 3.2.1.173 pectin pectin (rhamnogalacturonan II) GH139 alpha-2-O-Me-L-fucosidase 3.2.1.- alpha-glucan starch, glycogen and related polysaccharides and oligosaccharides GH14 beta-amylase 3.2.1.2 pectin pectin (rhamnogalacturonan II) GH140 beta-1,2-apiosidase 3.2.1.- pectin pectin (rhamnogalacturonan II) GH141 alpha-L-fucosidase 3.2.1.51 xylan xylan GH141 xylanase 3.2.1.8 pectin pectin (rhamnogalacturonan II) GH142 beta-L-arabinofuranosidase 3.2.1.185 pectin pectin (rhamnogalacturonan II) GH143 2-keto-3-deoxy-D-lyxo-heptulosaric acid hydrolase 3.2.1.- beta-glucan beta-1,2-glucan (bacteria) GH144 beta-1,2-glucooligosaccharide sophorohydrolase 3.2.1.214 beta-glucan beta-1,2-glucan (bacteria) GH144 endo-beta-1,2-glucanase 3.2.1.71 arabinan arabinan GH146 beta-L-arabinofuranosidase 3.2.1.185 beta-galactan galactan GH147 beta-galactosidase 3.2.1.89 beta-galactan galactan GH147 beta-galactosidase 3.2.1.23 beta-mannan glucomannan GH148 beta-1,3-glucanase 3.2.1.4 beta-glucan beta-glucan and lichenin GH148 beta-1,3-glucanase 3.2.1.- beta-glucan beta-1,3-glucan GH149 beta-1,3-glucan phosphorylase 2.4.1.97 starch starch GH15 dextran dextrinase 2.4.1.2 trehalose trehalose GH15 alpha,alpha-trehalase 3.2.1.28 starch starch GH15 glucoamylase 3.2.1.3 starch starch GH15 glucodextranase 3.2.1.70 carrageenan carrageenan GH150 Iota-carrageenase 3.2.1.162 human milk polysaccharide fucosylated human milk oligosaccharides GH151 alpha-L-fucosidase 3.2.1.51 beta-glucan beta-1,3-glucan (fungal lentinan) GH152 beta-1,3-glucanase 3.2.1.39 exo-polysaccharide deacetylated poly-β(1,6)-N-acetyl-glucosamine (bacterial PNAG for biofilm) GH153 poly-beta-1,6-D-glucosamine hydrolase 3.2.1.- arabinogalactan protein arabinogalactan proteins GH154 beta-1,6-D-glucuronidase 3.2.1.- arabinogalactan protein arabinogalactan proteins GH154 beta-glucuronidase 3.2.1.31 host glycan sialic acid (O-glycan, N-glycan, mucin, host glycan) GH156 exo-alpha-sialidase 3.2.1.18 beta-glucan beta-glucans (bacteria curdlan) GH157 endo-beta-1,3-glucanase / laminarinase 3.2.1.39 beta-glucan beta-glucans (yeast, seaweed, and plant) GH158 endo-beta-1,3-glucanase 3.2.1.39 beta-galactan beta-galactoside GH159 beta-D-galactofuranosidase 3.2.1.146 chitin chitin GH16 chitin beta-1,6-glucanosyltransferase 2.4.1.- beta-glucan beta-1,3-glucan GH16 beta-transglycosidase 2.4.1.- xyloglucan xyloglucan (plant) GH16 xyloglucan:xyloglucosyltransferase 2.4.1.207 host glycan mucin-type O-glycans GH16 endo-beta-1,4-galactosidase 3.2.1.- exo-polysaccharide exopolysaccharides (bacteria) GH16 beta-glycosidase 3.2.1.- carrageenan carrageenan GH16 beta-carrageenase 3.2.1.- host glycan keratan sulfate (host glycan) GH16 keratan-sulfate endo-1,4-beta-galactosidase 3.2.1.103 xyloglucan xyloglucan GH16 xyloglucanase 3.2.1.151 porphyran porphyran (red algal beta-galactose-sulfate) GH16 [retaining] beta-porphyranase 3.2.1.178 arabinogalactan protein arabinogalactan proteins GH16 endo-beta-1,3-galactanase 3.2.1.181 host glycan hyaluronate (glycosaminoglycan of host glycan) GH16 hyaluronidase 3.2.1.35 beta-glucan beta-1,3-glucan (fungi, algae, plant) GH16 endo-1,3-beta-glucanase / laminarinase 3.2.1.39 beta-glucan beta-1,3-1,4-glucan (laminarin, lichenin and cereal D-glucans) GH16 endo-1,3(4)-beta-glucanase 3.2.1.6 beta-glucan beta-1,3-1,4-glucan (laminarin, lichenin and cereal D-glucans) GH16 licheninase 3.2.1.73 agarose agarose GH16 beta-agarase 3.2.1.81 carrageenan carrageenan GH16 kappa-carrageenase 3.2.1.83 exo-polysaccharide exopolysaccharides (bacteria) GH160 endo-beta-1,4-galactosidase 3.2.1.- beta-glucan beta-1,3-glucan (fungi, algae, plant) GH161 beta-1,3-glucan phosphorylase 2.4.1.97 beta-glucan beta-1,2-glucan (bacteria) GH162 endo-beta-1,2-glucanase 3.2.1.71 host glycan N-glycan (host glycan) GH163 endo-beta-N-acetylglucosaminidase cleaving GlcNAc-beta-1,2-Man 3.2.1.- beta-mannan beta-mannoside GH164 beta-mannosidase 3.2.1.25 beta-galactan beta-galactoside GH165 beta-galactosidase 3.2.1.23 alpha-galactan exopolysaccharide galactosaminogalactan (fungal GAG) GH166 alpha-1,4-galactosaminogalactan hydrolase 3.2.1.- carrageenan carrageenan GH167 beta-carrageenase 3.2.1.- fucoidan Sulfated fucans (algae) GH168 endo-alpha-(1,3)-L-fucanase 3.2.1.211 exo-polysaccharide capsular polysaccharide (bacteria) GH169 beta-1,4-D-glucuronidase 3.2.1.- exo-polysaccharide capsular polysaccharide (bacteria) GH169 beta-glucuronidase 3.2.1.31 beta-glucan beta-1,3-glucan (fungi, algae, plant) GH17 beta-1,3-glucanosyltransglycosylase 2.4.1.- beta-glucan beta-1,3-glucan (fungi) GH17 beta-1,3-glucosidase 3.2.1.- abscisic acid abscisic acid (plant) GH17 ABA-specific beta-glucosidase 3.2.1.175 beta-glucan beta-1,3-glucan (algae, plant) GH17 glucan endo-1,3-beta-glucosidase 3.2.1.39 beta-glucan beta-1,3-1,4-glucan (laminarin, lichenin and cereal D-glucans) GH17 licheninase 3.2.1.73 peptidoglycan peptidoglycan GH170 6-phospho-N-acetylmuramidase 3.2.1.- peptidoglycan peptidoglycan GH171 peptidoglycan beta-N-acetylmuramidase 3.2.1.92 fructan fructooligosaccharides GH172 difructose-anhydride synthase 3.2.1.134 pectin beta-galactoside (pectin) GH173 β-galactosidase (EC 3.2.1.23) 3.2.1.23 peptidoglycan peptidoglycan GH18 peptidoglycan hydrolase with endo-beta-N-acetylglucosaminidase specificity 3.2.1.- chitin chitooligosaccharides (symbiotic nitrogen-fixing bacteria) GH18 Nod factor hydrolase 3.2.1.- chitin chitin GH18 chitinase 3.2.1.14 peptidoglycan peptidoglycan GH18 lysozyme 3.2.1.17 host glycan N-glycan (host glycan) GH18 endo-beta-N-acetylglucosaminidase 3.2.1.96 chitin chitin GH19 chitinase 3.2.1.14 chitin chitin GH19 chitinase 3.2.1.- peptidoglycan peptidoglycan GH19 lysozyme 3.2.1.17 pectin pectin (rhamnogalacturonan II) GH2 alpha-L-arabinopyranosidase 3.2.1.- pectin pectin (rhamnogalacturonan II) GH2 beta-galacturonidase 3.2.1.- alpha-mannan galactomannan (fungi) GH2 beta-D-galactofuranosidase 3.2.1.146 host glycan N-glycan (plant) GH2 mannosylglycoprotein endo-beta-mannosidase 3.2.1.152 chitosan chitosan or chitosan oligosaccharides (nonacetylated chitin) GH2 exo-beta-glucosaminidase 3.2.1.165 beta-glucan beta-glucoside GH2 beta-glucosidase 3.2.1.21 beta-galactan beta-galactoside GH2 beta-galactosidase 3.2.1.23 beta-mannan beta-mannoside GH2 beta-mannosidase 3.2.1.25 beta-glucuronan beta-glucuronoside GH2 beta-glucuronidase 3.2.1.31 xylan beta-xyloside GH2 beta-xylosidase 3.2.1.37 arabinan arabinan GH2 alpha-L-arabinofuranosidase 3.2.1.55 exo-polysaccharide capsular polysaccharide (bacteria) GH20 beta-1,6-N-acetylglucosaminidase 3.2.1.- host glycan mucin GH20 beta-6-SO3-N-acetylglucosaminidase 3.2.1.- human milk polysaccharide lacto-N-tetraose (human milk oligosaccharides) GH20 lacto-N-biosidase 3.2.1.140 host glycan N-glycan (host glycan, human milk oligosaccharides, chitin) GH20 beta-hexosaminidase 3.2.1.52 peptidoglycan peptidoglycan GH22 lysozyme type C 3.2.1.17 peptidoglycan peptidoglycan GH22 lysozyme type i 3.2.1.17 chitin chitin GH23 chitinase 3.2.1.14 peptidoglycan peptidoglycan GH23 lysozyme type G 3.2.1.17 peptidoglycan peptidoglycan GH23 peptidoglycan lyase ( also known in the literature as peptidoglycan lytic transglycosylase) 4.2.2.n1 peptidoglycan peptidoglycan GH24 lysozyme 3.2.1.17 peptidoglycan peptidoglycan GH25 lysozyme 3.2.1.17 beta-mannan beta-mannan GH26 mannobiose-producing exo-beta-mannanase 3.2.1.- beta-mannan beta-mannan (plant) GH26 exo-beta-1,4-mannobiohydrolase 3.2.1.100 xylan beta(1,3)-xylan (algae) GH26 beta-1,3-xylanase 3.2.1.32 beta-glucan beta-glucan GH26 lichenase / endo-beta-1,3-1,4-glucanase 3.2.1.73 beta-mannan beta-mannan (plant) GH26 beta-mannanase 3.2.1.78 raffinose raffinose family oligosaccharide (plant) GH27 galactan:galactan galactosyltransferase 2.4.1.- alpha-galactan alpha-galactoside, galactose oligosaccharides (plant), galactomannans (plant) and galactolipid (animal) GH27 alpha-galactosidase 3.2.1.22 host glycan human blood group A, mucin, host glycan GH27 alpha-N-acetylgalactosaminidase 3.2.1.49 arabinogalactan protein arabinogalactan GH27 beta-L-arabinopyranosidase 3.2.1.88 starch dextran and isomalto-oligosaccharides (bacteria) GH27 isomalto-dextranase 3.2.1.94 pectin xylogalacturonan (pectin) GH28 xylogalacturonan hydrolase 3.2.1.- pectin galacturonan (pectin) GH28 polygalacturonase 3.2.1.15 pectin rhamnogalacturonan (pectin) GH28 rhamnogalacturonase 3.2.1.171 pectin pectin (rhamnogalacturonan I) GH28 rhamnogalacturonan alpha-1,2-galacturonohydrolase 3.2.1.173 pectin galacturonan (pectin) GH28 exo-polygalacturonase 3.2.1.67 pectin galacturonan (pectin) GH28 exo-polygalacturonosidase 3.2.1.82 host glycan human milk oligosaccharides, mucin, host glycan GH29 alpha-1,3/1,4-L-fucosidase 3.2.1.111 host glycan human milk oligosaccharides, mucin, host glycan GH29 alpha-L-fucosidase 3.2.1.51 host glycan human milk oligosaccharides, mucin, host glycan GH29 alpha-1,2-L-fucosidase 3.2.1.63 peptidoglycan peptidoglycan GH3 beta-N-acetylglucosaminide phosphorylases 2.4.1.- beta-glucan beta-1,3-1,4-glucan (laminarin, lichenin and cereal D-glucans) GH3 exo-1,3-1,4-glucanase 3.2.1.- beta-glucan beta-1,2-glucan (bacteria) GH3 beta-1,2-glucosidase 3.2.1.- beta-glucan beta-1,3-glucan (laminarin, lichenin and cereal D-glucans) GH3 beta-1,3-glucosidase 3.2.1.- xyloglucan xyloglucan (plant) GH3 isoprimeverose-producing oligoxyloglucan hydrolase 3.2.1.120 polyphenol coniferin (glucoside of coniferyl alcohol) GH3 coniferin beta-glucosidase 3.2.1.126 xyloglucan xyloglucan (plant) GH3 xyloglucan-specific exo-beta-1,4-glucanase / exo-xyloglucanase 3.2.1.155 polyphenol protodioscin (plant steroidal saponin) GH3 protodioscin 26-O-β-D-glucosidase 3.2.1.186 beta-glucan beta-glucan GH3 beta-glucosidase 3.2.1.21 xylan xylan GH3 xylan 1,4-beta-xylosidase 3.2.1.37 host glycan glycosphingolipid (host glycan) GH3 beta-glucosylceramidase 3.2.1.45 chitin chitin, peptidoglycan GH3 beta-N-acetylhexosaminidase 3.2.1.52 arabinan arabinan, arabinoxylan GH3 alpha-L-arabinofuranosidase 3.2.1.55 beta-glucan beta-1,3-glucan (laminarin, lichenin and cereal D-glucans) GH3 lichenase / endo-beta-1,3-1,4-glucanase 3.2.1.73 beta-glucan cellodextrin (beta-1,3-glucan) GH3 glucan 1,4-beta-glucosidase 3.2.1.74 xylan xylan GH30 [reducing end] beta-xylosidase 3.2.1.- xylan xylan GH30 glucuronoarabinoxylan endo-beta-1,4-xylanase 3.2.1.136 arabinogalactan protein arabinogalactan proteins GH30 endo-beta-1,6-galactanase 3.2.1.164 beta-glucan beta-glucan GH30 beta-glucosidase 3.2.1.21 beta-glucuronan beta-glucuronoside GH30 beta-glucuronidase 3.2.1.31 xylan xylan GH30 beta-xylosidase 3.2.1.37 beta-fucosides beta-fucoside GH30 beta-fucosidase 3.2.1.38 host glycan glucosylsphingosine, glucosylceramide (host glycans) GH30 glucosylceramidase 3.2.1.45 beta-glucan beta-1,6-glucan (fungal and algal cell wall) GH30 beta-1,6-glucanase 3.2.1.75 xylan xylan GH30 endo-beta-1,4-xylanase 3.2.1.8 starch glycogen and starch GH31 oligosaccharide alpha-1,4-glucosyltransferase 2.4.1.161 xyloglucan xyloglucan (plant) GH31 alpha-xylosidase 3.2.1.177 polyphenol sulfoquinovoside (plant sulfolipid) GH31 sulfoquinovosidase 3.2.1.199 starch starch GH31 alpha-glucosidase 3.2.1.20 alpha-galactan alpha-galactoside GH31 alpha-galactosidase 3.2.1.22 alpha-mannan alpha-mannoside GH31 alpha-mannosidase 3.2.1.24 sucrose sucrose GH31 sucrase-isomaltase 3.2.1.48 host glycan human blood group A, mucin, host glycan GH31 alpha-N-acetylgalactosaminidase 3.2.1.49 starch glycogen and starch GH31 alpha-1,3-glucosidase 3.2.1.84 starch glycogen and starch GH31 alpha-glucan lyase 4.2.2.13 fructan levan (fructan) GH32 levan fructosyltransferase 2.4.1.- fructan graminan- and levan-type fructans GH32 [retaining] sucrose:sucrose 6-fructosyltransferase (6-SST) 2.4.1.- fructan fructan(inulin, levan and sucrose) GH32 cycloinulo-oligosaccharide fructanotransferase 2.4.1.- fructan fructan(inulin, levan and sucrose) GH32 sucrose:fructan 6-fructosyltransferase 2.4.1.10 fructan fructan(inulin, levan and sucrose) GH32 fructan:fructan 1-fructosyltransferase 2.4.1.100 fructan fructan(inulin, levan and sucrose) GH32 fructan:fructan 6G-fructosyltransferase 2.4.1.243 fructan fructan(inulin, levan and sucrose) GH32 sucrose:sucrose 1-fructosyltransferase 2.4.1.99 fructan fructan GH32 fructan beta-(2,1)-fructosidase/1-exohydrolase 3.2.1.153 fructan fructan GH32 fructan beta-(2,6)-fructosidase/6-exohydrolase 3.2.1.154 fructan fructan(inulin, levan and sucrose) GH32 invertase 3.2.1.26 fructan fructan(inulin, levan and sucrose) GH32 beta-2,6-fructan 6-levanbiohydrolase 3.2.1.64 fructan levan (fructan) GH32 endo-levanase 3.2.1.65 fructan inulin GH32 endo-inulinase 3.2.1.7 fructan fructan(inulin, levan and sucrose) GH32 exo-inulinase 3.2.1.80 sialic acid sialic acid GH33 trans-sialidase 2.4.1.- pectin pectin (rhamnogalacturonan II), lipopolysaccharides (bacteria) GH33 Kdo hydrolase 3.2.1.- sialic acid sialic acid (O-glycan, N-glycan, mucin, host glycan) GH33 sialidase or neuraminidase 3.2.1.18 sialic acid sialic acid (O-glycan, N-glycan, mucin, host glycan) GH33 anhydrosialidase 4.2.2.15 sialic acid sialic acid (O-glycan, N-glycan, mucin, host glycan) GH34 sialidase or neuraminidase 3.2.1.18 beta-galactan galactan and arabinogalactan GH35 beta-1,3-galactosidase 3.2.1.- chitin chitosan, chitin GH35 exo-beta-glucosaminidase 3.2.1.165 pectin beta-galactoside (pectin) GH35 beta-galactosidase 3.2.1.23 raffinose raffinose/stachyose oligosaccharides (plant seeds) GH36 stachyose synthase 2.4.1.67 raffinose raffinose oligosaccharides GH36 raffinose synthase 2.4.1.82 alpha-galactan alpha-galactoside (galactose oligosaccharides, galactomannans and galactolipid) GH36 alpha-galactosidase 3.2.1.22 host glycan acetylgalactosamine (human blood group A and b, mucin glycoproteins) GH36 alpha-N-acetylgalactosaminidase 3.2.1.49 trehalose alpha-trehalose GH37 alpha,alpha-trehalase 3.2.1.28 alpha-mannan alpha-mannan (fungi) GH38 mannosyl-oligosaccharide alpha-1,3-mannosidase 3.2.1.- host glycan N-glycan, O-glycans, alpha-mannan (fungi) GH38 mannosyl-oligosaccharide alpha-1,2-mannosidase 3.2.1.113 host glycan N-glycan GH38 mannosyl-oligosaccharide alpha-1,3-1,6-mannosidase 3.2.1.114 host glycan N-glycan, O-glycans, alpha-mannan (fungi) GH38 alpha-mannosidase 3.2.1.24 beta-glucan beta-glucoside (exopolysaccharide, cellubiose) GH39 beta-glucosidase 3.2.1.21 beta-galactan beta-galactoside GH39 beta-galactosidase 3.2.1.23 xylan xylan GH39 beta-xylosidase 3.2.1.37 xylan arabinoxylan (galacto-(α-1,2)-arabinosidase) GH39 alpha-L-arabinofuranosidase 3.2.1.55 cellulose beta-glucoside (cellubiose) GH39 exo-beta-1,4-glucanase / cellodextrinase 3.2.1.74 host glycan glycosaminoglycans heparan sulfate and dermatan sulfate (host glycan) GH39 alpha-L-iduronidase 3.2.1.76 palatinose isomaltulose (palatinose, from honey and sugar cane) GH4 palatinase 3.2.1.- sucrose sucrose and its isomeric disaccharides GH4 maltose-6-phosphate glucosidase 3.2.1.122 xylan alpha-glucuronide in glucuronoxylan GH4 alpha-glucuronidase 3.2.1.139 starch maltose and other small maltooligosaccharides GH4 alpha-glucosidase 3.2.1.20 raffinose alpha-galactoside (raffinose family of oligosaccharides) GH4 alpha-galactosidase 3.2.1.22 pectin galacturonides (polygalacturonan of pectin) GH4 alpha-galacturonase 3.2.1.67 beta-glucan beta-glucoside (sinigrin, cellubiose) GH4 6-phospho-beta-glucosidase 3.2.1.86 arabinan paeonolide, ginsenoside, arabinoxylan, and arabinan GH42 alpha-L-arabinopyranosidase 3.2.1.- arabinogalactan protein beta-1,6/1,3-galactoside (arabinogalactan) GH42 beta-galactosidase 3.2.1.23 arabinan arabinan, arabinoxylan GH43 alpha-1,2-L-arabinofuranosidase 3.2.1.- arabinan arabinan, arabinoxylan GH43 exo-alpha-1,5-L-arabinofuranosidase 3.2.1.- arabinan arabinan GH43 [inverting] exo-alpha-1,5-L-arabinanase 3.2.1.- xylan beta-1,3-xylan (algae) GH43 beta-1,3-xylosidase 3.2.1.- arabinogalactan protein beta-1,3-galactan, arabinogalactan GH43 exo-beta-1,3-galactanase 3.2.1.145 beta-galactan beta-galactofuranoside GH43 beta-D-galactofuranosidase 3.2.1.146 xylan xylan GH43 beta-xylosidase 3.2.1.37 xylan arabinoxylan GH43 alpha-L-arabinofuranosidase 3.2.1.55 xylan xylan GH43 xylanase 3.2.1.8 arabinan arabinan GH43 [inverting] endo-alpha-1,5-L-arabinanase 3.2.1.99 xyloglucan xyloglucan GH44 xyloglucanase 3.2.1.151 beta-glucan cellulose, lichenin and cereal beta-glucan GH44 endoglucanase 3.2.1.4 xyloglucan xyloglucan GH45 xyloglucan-specific endo-beta-1,4-glucanase / endo-xyloglucanase 3.2.1.151 beta-glucan cellulose, lichenin and cereal beta-glucan GH45 endoglucanase 3.2.1.4 beta-mannan mannans, galactomannans and glucomannan GH45 endo-beta-1,4-mannanase 3.2.1.78 chitosan chitosan GH46 chitosanase 3.2.1.132 host glycan protein-linked N-glycan (host glycan) GH47 alpha-mannosidase 3.2.1.113 chitin chitin and chitodextrin GH48 chitinase 3.2.1.14 cellulose cellulose GH48 reducing end-acting cellobiohydrolase 3.2.1.176 cellulose cellulose GH48 endo-beta-1,4-glucanase 3.2.1.4 arabinan sulfated arabinan GH49 sulfated arabinan endo-1,4-beta-L-arabinanase 3.2.1.- alpha-glucan dextran (branched alpha-glucan) GH49 dextranase 3.2.1.11 alpha-glucan pullulan (starch degradation by fungi) GH49 isopullulanase 3.2.1.57 alpha-glucan dextran (branched alpha-glucan) GH49 dextran 1,6-alpha-isomaltotriosidase 3.2.1.95 beta-mannan beta-mannan (plant) GH5 mannan transglycosylase 2.4.1.- beta-mannan beta-mannan GH5 beta-1,3-mannanase 3.2.1.- xylan arabinoxylans GH5 arabinoxylan-specific endo-beta-1,4-xylanase 3.2.1.- beta-glycan beta-glycoside GH5 beta-glycosidase 3.2.1.- polyphenol rutin (polyphenol) GH5 beta-rutinosidase /alpha-L-rhamnose-(1,6)-beta-D-glucosidase 3.2.1.- beta-mannan glucomannan GH5 glucomannan-specific endo-beta-1,4-glucanase 3.2.1.- glycolipid sterylglucoside (fungi) GH5 steryl beta-glucosidase 3.2.1.104 glycolipid glycosphingolipids GH5 endoglycoceramidase 3.2.1.123 chitosan chitosan GH5 chitosanase 3.2.1.132 arabinogalactan protein arabinogalactan (bacteria) GH5 beta-D-galactofuranosidase 3.2.1.146 beta-glycan betaiglycoside GH5 beta-primeverosidase 3.2.1.149 xyloglucan xyloglucan GH5 xyloglucan-specific endo-beta-1,4-glucanase 3.2.1.151 arabinogalactan protein arabinogalactan GH5 endo-beta-1,6-galactanase 3.2.1.164 polyphenol naringenin (flavonoid) and tea aroma GH5 beta-glucosidase 3.2.1.21 beta-mannan N-glycan, beta-mannan GH5 beta-mannosidase 3.2.1.25 beta-glucan laminarin (algae), pustulan (fungi) GH5 endo-beta-1,3-glucanase / laminarinase 3.2.1.39 beta-glucan cellulose, beta-glucan GH5 endo-beta-1,4-glucanase / cellulase 3.2.1.4 glycolipid fungus-specific glucosylceramide (glycolipid) GH5 beta-glucosylceramidase 3.2.1.45 glycolipid glycosphingolipid, galactolipids GH5 beta-galactosylceramidase 3.2.1.46 chitin chitin GH5 beta-N-acetylhexosaminidase 3.2.1.52 arabinan arabinan GH5 alpha-L-arabinofuranosidase 3.2.1.55 beta-glucan beta-1,3-glucans (laminarin) GH5 glucan beta-1,3-glucosidase 3.2.1.58 beta-glucan beta-glucan(contains both (1->3)- and (1->4)-bonds),lichenin and cereal beta-glucan GH5 lichenase / endo-beta-1,3-1,4-glucanase 3.2.1.73 cellulose cellulose and similar substrates GH5 exo-beta-1,4-glucanase / cellodextrinase 3.2.1.74 beta-glucan laminarin (algae), pustulan (fungi) GH5 glucan endo-1,6-beta-glucosidase 3.2.1.75 beta-mannan mannans, galactomannans and glucomannan GH5 mannan endo-beta-1,4-mannosidase 3.2.1.78 xylan xylan GH5 endo-beta-1,4-xylanase 3.2.1.8 cellulose cellulose GH5 cellulose beta-1,4-cellobiosidase 3.2.1.91 agarose porphyran, agarose GH50 beta-agarase 3.2.1.81 arabinan arabinan GH51 beta-xylosidase 3.2.1.37 beta-glucan cellulose, beta-glucan GH51 endoglucanase 3.2.1.4 arabinan arabinan, arabinoxylan GH51 alpha-L-arabinofuranosidase 3.2.1.55 xylan xylan GH51 endo-beta-1,4-xylanase 3.2.1.8 xylan xylan GH52 beta-xylosidase 3.2.1.37 arabinogalactan protein arabinogalactan GH53 endo-beta-1,4-galactanase 3.2.1.89 xylan arabinan, arabinoxylan GH54 beta-xylosidase 3.2.1.37 arabinan arabinan, arabinoxylan GH54 alpha-L-arabinofuranosidase 3.2.1.55 beta-glucan laminarin (algae) GH55 laminarin-degrading enzyme 3.2.1.- beta-glucan laminarin (algae), pustulan (fungi) GH55 endo-beta-1,3-glucanase 3.2.1.39 beta-glucan laminarin (algae), pustulan (fungi) GH55 exo-beta-1,3-glucanase 3.2.1.58 host glycan glycosaminoglycan, hyaluronan, chondroitin sulfate, host glycan GH56 chondroitin hydrolase 3.2.1.- host glycan glycosaminoglycan, hyaluronan, chondroitin sulfate, host glycan GH56 hyaluronidase 3.2.1.35 beta-glucan beta-1,4-glucan, glycogen GH57 branching enzyme 2.4.1.18 starch starch, glycogen, and malto-oligosaccharides GH57 4-alpha-glucanotransferase 2.4.1.25 starch starch, glycogen and related polysaccharides and oligosaccharides(containing three or more (1->4)-alpha-linked D-glucose units) GH57 alpha-amylase 3.2.1.1 alpha-galactan alpha-galactoside, melibiose and raffinose GH57 alpha-galactosidase 3.2.1.22 alpha-glucan pullulan, maltodextrins and cyclodextrin GH57 amylopullulanase 3.2.1.41 alpha-glucan pullulan, maltodextrins and cyclodextrin GH57 cyclomaltodextrinase 3.2.1.54 sialic acid sialic acid GH58 endo-N-acetylneuraminidase or endo-sialidase 3.2.1.129 beta-galactan beta-galactoside GH59 beta-galactosidase 3.2.1.23 glycolipid galactosylceramide, sphingolipids, galactolipids GH59 galactocerebrosidase 3.2.1.46 cellulose cellulose GH6 endoglucanase 3.2.1.4 cellulose cellulose GH6 lichenase / endo-beta-1,3-1,4-glucanase 3.2.1.73 cellulose cellulose GH6 cellobiohydrolase 3.2.1.91 arabinan arabinoxylans, arabinogalactans, arabinan GH62 alpha-L-arabinofuranosidase 3.2.1.55 host glycan N-glycan GH63 processing alpha-glucosidase 3.2.1.106 alpha-glucan mannosylglycerate GH63 mannosylglycerate alpha-mannosidase / mannosylglycerate hydrolase 3.2.1.170 alpha-glucan nigerose, trehalose, kojibiose, and maltooligosaccharide GH63 alpha-glucosidase 3.2.1.20 alpha-glucan glucosylglycerate GH63 glucosylglycerate hydrolase 3.2.1.208 alpha-glucan nigerose, trehalose, kojibiose, and maltooligosaccharide GH63 alpha-1,3-glucosidase 3.2.1.84 beta-glucan beta-1,3-glucan (fungal cell walls) GH64 beta-1,3-glucanase 3.2.1.39 alpha-glucan kojibiose and alpha-1,2-oligoglucan GH65 2-O-alpha-glucopyranosylglycerol: phosphate beta-glucosyltransferase 2.4.1.- alpha-glucan trehalose, kojibiose GH65 trehalose-6-phosphate phosphorylase 2.4.1.216 alpha-glucan kojibiose GH65 kojibiose phosphorylase 2.4.1.230 alpha-glucan nigerose GH65 nigerose phosphorylase 2.4.1.279 exo-polysaccharide glucopyranosyl-α-1,3-rhamnose (bacteria lipopolysaccharides or capsule polysaccharides) GH65 3-O-alpha-glucopyranosyl-L-rhamnose phosphorylase 2.4.1.282 alpha-glucan 1,3-α-oligoglucan GH65 1,3-α-oligoglucan phosphorylase 2.4.1.334 alpha-glucan trehalose GH65 trehalose phosphorylase 2.4.1.64 alpha-glucan maltose (α1,4) GH65 maltose phosphorylase 2.4.1.8 alpha-glucan Glc-α1,2-Gal of collagen (animal) GH65 alpha-glucosyl-1,2-beta-galactosyl-L-hydroxylysine alpha-glucosidase 3.2.1.107 alpha-glucan trehalose GH65 alpha,alpha-trehalase 3.2.1.28 alpha-glucan dextran (α1,6) GH66 cycloisomaltooligosaccharide glucanotransferase 2.4.1.248 alpha-glucan dextran GH66 dextranase 3.2.1.11 xylan xylan side chain GH67 xylan alpha-1,2-glucuronidase 3.2.1.131 xylan xylan side chain GH67 alpha-glucuronidase 3.2.1.139 fructan synthesize β (2-6)-linked fructan levan with sucrose as substrate GH68 levansucrase 2.4.1.10 fructan synthesize β (2-1)-linked fructan GH68 inulosucrase 2.4.1.9 fructan synthesize β (2-1)-linked fructan GH68 beta-fructofuranosidase 3.2.1.26 chitosan chitosan GH7 chitosanase 3.2.1.132 cellulose cellulose and similar substrates GH7 reducing end-acting cellobiohydrolase 3.2.1.176 cellulose cellulose, lichenin and cereal beta-glucan GH7 endo-beta-1,4-glucanase 3.2.1.4 cellulose beta-glucan, lichenin GH7 endo-beta-1,3-1,4-glucanase 3.2.1.73 alpha-glucan reuteran GH70 reuteransucrase 2.4.1.- alpha-glucan starch,maltose, beta-glucan ,lichenan,laminarin, xylan GH70 alpha-4,6-glucanotransferase 2.4.1.- alpha-glucan glucan GH70 alpha-1,2-branched dextransucrase 2.4.1.- alpha-glucan glucan GH70 alpha-4,3-glucanotransferase 2.4.1.- alpha-glucan sucrose GH70 alternansucrase 2.4.1.140 alpha-glucan sucrose GH70 dextransucrase 2.4.1.5 alpha-glucan α-1,3-glucan GH71 alpha-1,3-glucanase 3.2.1.59 beta-glucan β-1,3-glucan GH72 beta-1,3-glucanosyltransglycosylase 2.4.1.- peptidoglycan peptidoglycan GH73 peptidoglycan hydrolase with endo-beta-N-acetylglucosaminidase specificity 3.2.1.- peptidoglycan peptidoglycan GH73 lysozyme 3.2.1.17 peptidoglycan peptidoglycan GH73 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 3.2.1.96 xyloglucan oligoxyloglucan GH74 oligoxyloglucan reducing end-specific cellobiohydrolase 3.2.1.150 xyloglucan xyloglucan GH74 xyloglucanase 3.2.1.151 cellulose carboxymethyl cellulose GH74 endoglucanase 3.2.1.4 chitosan chitosan GH75 chitosanase 3.2.1.132 alpha-mannan yeast α-mannan (yeast cell wall) GH76 alpha-1,6-mannanase 3.2.1.101 alpha-glucan alpha-glucose GH76 alpha-glucosidase 3.2.1.20 starch amylomaltase GH77 amylomaltase or 4-alpha-glucanotransferase 2.4.1.25 pectin rhamnogalacturonan GH78 rhamnogalacturonan alpha-L-rhamnohydrolase 3.2.1.174 alpha-rhamnoside α-L-rhamnosidase in polyphenol (naringin, rutin, hesperidin), ulvan, pectin, arabinogalactan-protein GH78 alpha-L-rhamnosidase 3.2.1.40 arabinogalactan protein arabinogalactan protein GH79 beta-4-O-methyl-glucuronidase 3.2.1.- host glycan heparan sulfate proteoglycans GH79 heparanase 3.2.1.166 host glycan heparan sulfate proteoglycans GH79 baicalin beta-glucuronidase 3.2.1.167 arabinogalactan protein arabinogalactan protein GH79 beta-glucuronidase 3.2.1.31 host glycan hyaluronan GH79 hyaluronoglucuronidase 3.2.1.36 chitosan chitosan GH8 chitosanase 3.2.1.132 xylan xylan GH8 reducing-end-xylose releasing exo-oligoxylanase 3.2.1.156 cellulose cellulose GH8 cellulase 3.2.1.4 beta-glucan beta-glucan (laminarin, lichenin and cereal D-glucans) GH8 endo-beta-1,3(4)-glucanase / lichenase-laminarinase 3.2.1.6 beta-glucan beta-glucan (lichenin and cereal beta-glucan) GH8 licheninase 3.2.1.73 xylan xylan GH8 endo-1,4-beta-xylanase 3.2.1.8 chitosan chitosan GH80 chitosanase 3.2.1.132 beta-glucan β-1,3-glucan GH81 endo-beta-1,3-glucanase 3.2.1.39 carrageenan iota-carrageenans GH82 ι-carrageenase 3.2.1.157 host glycan paramyxovirus cleaves sialic acid of host glycans GH83 neuraminidase 3.2.1.18 host glycan cleave beta-O-linked GlcNAc of host glycan GH84 [protein]-3-O-(GlcNAc)-L-Ser/Thr beta-N-acetylglucosaminidase 3.2.1.169 host glycan hyaluronan GH84 hyaluronidase 3.2.1.35 host glycan mucin GH84 N-acetyl beta-glucosaminidase 3.2.1.52 host glycan N-linked glycans GH85 endo-beta-N-acetylglucosaminidase 3.2.1.96 agarose porphyran GH86 beta-porphyranase 3.2.1.178 agarose porphyran, agarose GH86 beta-agarase 3.2.1.81 alpha-glucan nigeran (alpha-glucan in fungi) GH87 alpha-1,3-glucanase 3.2.1.59 alpha-glucan α-1,3-glucan GH87 mycodextranase 3.2.1.61 host glycan sulfated glycosaminoglycans GH88 d-4,5-unsaturated beta-glucuronyl hydrolase 3.2.1.- host glycan sulfated glycosaminoglycans GH88 unsaturated chondroitin disaccharide hydrolase 3.2.1.180 host glycan α-Linked N-acetylglucosamine mucin GH89 alpha-N-acetylglucosaminidase 3.2.1.50 beta-glucan xanthan GH9 endo-beta-1,4-glucanase (xanthanase) 3.2.1.- beta-glucan xyloglucan GH9 xyloglucan-specific endo-beta-1,4-glucanase / endo-xyloglucanase 3.2.1.151 chitosan chitosan or chitosan oligosaccharides GH9 exo-beta-glucosaminidase 3.2.1.165 cellulose cellulose GH9 endoglucanase 3.2.1.4 beta-glucan beta-glucan(laminarin, lichenin and cereal D-glucans) GH9 endo-beta-1,3(4)-glucanase / lichenase-laminarinase 3.2.1.6 beta-glucan beta-glucan, lichenin GH9 lichenase / endo-beta-1,3-1,4-glucanase 3.2.1.73 cellulose cellulose GH9 exo-beta-1,4-glucanase / cellodextrinase 3.2.1.74 cellulose cellulose and cellotetraose GH9 cellobiohydrolase 3.2.1.91 exo-polysaccharide lipo- or capsular polysaccharides GH90 endorhamnosidase 3.2.1.- fructan inulin GH91 difructofuranose 1,2':2,3' dianhydride hydrolase [DFA-IIIase] 3.2.1.- fructan inulin GH91 inulin lyase [DFA-I-forming] 4.2.2.17 fructan inulin GH91 inulin lyase [DFA-III-forming] 4.2.2.18 host glycan host N-glycan Man9(GlcNac)2 GH92 mannosyl-oligosaccharide alpha-1,3-mannosidase 3.2.1.- host glycan host N-glycan GH92 mannosyl-oligosaccharide alpha-1,6-mannosidase 3.2.1.- host glycan host N-glycan GH92 alpha-1,2-mannosidase 3.2.1.- host glycan host N-glycan GH92 alpha-1,3-mannosidase 3.2.1.- host glycan host N-glycan GH92 alpha-1,4-mannosidase 3.2.1.- host glycan host N-glycan GH92 mannosyl-1-phosphodiester alpha-1,P-mannosidase 3.2.1.- host glycan host N-glycan GH92 mannosyl-oligosaccharide alpha-1,2-mannosidase 3.2.1.113 host glycan host N-glycan GH92 alpha-mannosidase 3.2.1.24 arabinan arabinan (pectin) GH93 exo-alpha-L-1,5-arabinanase 3.2.1.- chitin chitin GH94 chitobiose phosphorylase 2.4.1.280 chitin 4-O-β-glucosyl-galactose GH94 4-O-β-D-glucosyl-D-galactose phosphorylase 2.4.1.- beta-glucan 1,2-β-oligoglucan GH94 β-1,2-oligoglucan phosphorylase 2.4.1.333 cellulose cellobiose GH94 cellobiose phosphorylase 2.4.1.20 beta-glucan laminarin GH94 laminaribiose phosphorylase 2.4.1.31 cellulose cellobionic acid GH94 cellobionic acid phosphorylase 2.4.1.321 cellulose cellodextrin GH94 cellodextrin phosphorylase 2.4.1.49 pectin, xylan plant pectic polysaccharide, xylan GH95 alpha-L-galactosidase 3.2.1.- host glycan alpha-L-fucoside GH95 alpha-L-fucosidase 3.2.1.51 xyloglucan, host glycan alpha1,2-L-fucosidase sugar GH95 alpha-1,2-L-fucosidase 3.2.1.63 agarose agarose GH96 alpha-agarase 3.2.1.158 alpha-glucan alpha-glucose residue GH97 alpha-glucosidase 3.2.1.20 alpha-glucan alpha-galactoside, alpha-fucoside GH97 alpha-galactosidase 3.2.1.22 alpha-glucan beta-glucose GH97 glucoamylase 3.2.1.3 host glycan blood group A and B substances, host glycans GH98 blood-group endo-beta-1,4-galactosidase 3.2.1.102 xylan xylan GH98 endo-beta-1,4-xylanase 3.2.1.8 host glycan host N-glycan GH99 glycoprotein endo-alpha-1,2-mannosidase 3.2.1.130 alpha-mannan alpha-mannans (fungi) GH99 mannan endo-1,2-alpha-mannanase 3.2.1.198 xyloglucan xyloglucan CE20 xyloglucan acetylesterase (XAC1771) 3.1.1.6 xylan Feruloyl-polysaccharide(esterified sugar) CE1 feruloyl esterase 3.1.1.73 xylan xylan CE1 acetyl xylan esterase 3.1.1.72 xylan A carboxylic ester(ester) CE1 carboxylesterase 3.1.1.1 xylan Acyl-CoA,Palmitoyl-CoA and other long-chain acyl-CoAs(ester) CE1 diacylglycerol O-acyltransferase 2.3.1.20 trehalose trehalose CE1 trehalose 6-O-mycolyltransferase 2.3.1.122 polyphenol Hydroxycinnamic acids(Phenolic acids) CE1 cinnamoyl esterase 3.1.1.- exo-polysaccharide biosynthesis of lipid A CE11 UDP-3-0-acyl N-acetylglucosamine deacetylase 3.5.1.108 xylan acetyl xylan CE12 acetyl xylan esterase 3.1.1.72 pectin pectin CE12 pectin acetylesterase 3.1.1.- pectin pectin CE12 rhamnogalacturonan acetylesterase 3.1.1.- pectin pectin CE13 pectin acetylesterase 3.1.1.- exo-polysaccharide glycosylphosphatidylinositol(lipid anchor ) CE14 N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase 3.5.1.89 chitin chitin CE14 chitin disaccharide deacetylase 3.5.1.105 chitin chitin CE14 diacetylchitobiose deacetylase 3.5.1.- chitin alkylating agents and xenobiotics(organic compound) CE14 mycothiol S-conjugate amidase 3.5.1.115 lignin lignin CE15 4-O-methyl-glucuronoyl methylesterase 3.5.1.- xylan various carbohydrate acetyl ester CE16 acetylesterase (active on various carbohydrate acetylesters) 3.1.1.6 beta-mannan acetylmannan CE17 acetylmannan esterase 3.1.1.- pectin pectin CE19 Family created after Bamford and coworkers [PMID=28329766] demonstrated the pectin methylesterase activity of BT1017 protein from Bacteroides thetaiotaomicron VPI-5482 xylan acetylxylan CE2 acetyl xylan esterase 3.1.1.72 xylan acetylxylan CE3 acetyl xylan esterase 3.1.1.72 chitin chitin CE4 chitin deacetylase 3.5.1.41 chitin Chitooligosaccharides CE4 chitooligosaccharide deacetylase 3.5.1.- peptidoglycan peptidoglycan CE4 peptidoglycan GlcNAc deacetylase 3.5.1.- peptidoglycan peptidoglycan CE4 peptidoglycan N-acetylmuramic acid deacetylase 3.5.1.- xylan acetylxylan CE4 acetyl xylan esterase 3.1.1.72 cutin cutin CE5 cutinase 3.1.1.74 xylan acetylxylan CE5 acetyl xylan esterase 3.1.1.72 xylan acetylxylan CE6 acetyl xylan esterase 3.1.1.72 xylan acetylxylan CE7 acetyl xylan esterase 3.1.1.72 cephalosporin C cephalosporin C(antibiotic) CE7 cephalosporin-C deacetylase 3.1.1.41 pectin pectin CE8 pectin methylesterase 3.1.1.11 host glycan host glycan CE9 N-acetylglucosamine 6-phosphate deacetylase 3.5.1.25 pectin pectin PL1 pectin lyase 4.2.2.10 pectin pectin PL1 pectate lyase 4.2.2.2 pectin homogalacturonan(de-esterified pectin) PL1 exo-pectate lyase 4.2.2.9 pectin pectin PL10 pectate lyase 4.2.2.2 pectin rhamnogalacturonan I(pectin from the plant cell wall) PL11 rhamnogalacturonan endolyase 4.2.2.23 pectin rhamnogalacturonan I(pectin from the plant cell wall) PL11 rhamnogalacturonan exolyase 4.2.2.24 host glycan Heparin and heparan sulfate(host glycan) PL12 heparin lyase / heparin lyase I 4.2.2.7 host glycan heparin sulfate(host glycan) PL12 heparin-sulfate lyase 4.2.2.8 host glycan Heparin and heparan sulfate(host glycan) PL13 heparin lyase 4.2.2.7 host glycan host glycan PL14 beta-1,4-glucuronan lyase 4.2.2.14 alginate alginate PL14 exo-oligoalginate lyase 4.2.2.26 alginate alginate PL14 poly(beta-mannuronate) lyase / M-specific alginate lyase 4.2.2.3 alginate alginate PL15 oligoalginate lyase / exo-alginate lyase 4.2.2.26 alginate alginate PL15 alginate lyase 4.2.2.3 host glycan Heparin and heparan sulfate(host glycan) PL15 heparin lyase / heparin lyase I 4.2.2.7 host glycan heparin sulfate(host glycan) PL15 heparin-sulfate lyase / heparin lyase III 4.2.2.8 host glycan hyaluronan PL16 hyaluronan lyase 4.2.2.1 alginate alginate PL17 oligoalginate lyase 4.2.2.26 alginate alginate PL17 alginate lyase 4.2.2.3 alginate alginate PL18 poly(alpha-L-guluronate) lyase / G-specific alginate lyase 4.2.2.11 alginate alginate PL18 alginate lyase 4.2.2.3 pectin pectin PL2 pectate lyase 4.2.2.2 pectin homogalacturonan(de-esterified pectin) PL2 exo-polygalacturonate lyase 4.2.2.9 host glycan host glycan PL20 endo-beta-1,4-glucuronan lyase 4.2.2.14 host glycan Heparin and heparan sulfate(host glycan) PL21 heparin lyase 4.2.2.7 host glycan heparin sulfate(host glycan) PL21 heparin-sulfate lyase 4.2.2.8 pectin pectin( D-galacturonate) PL22 oligogalacturonate lyase / oligogalacturonide lyase 4.2.2.6 pectin rhamnogalacturonan I(pectin from the plant cell wall) PL26 rhamnogalacturonan exolyase 4.2.2.24 host glycan glycosaminoglycans(host glycan) PL29 chondroitin-sulfate ABC endolyase 4.2.2.20 pectin pectate PL3 pectate lyase 4.2.2.2 host glycan hyaluronate(host glycan) PL30 hyaluronate lyase 4.2.2.1 host glycan host glycan PL31 endo-beta-1,4-glucuronan lyase 4.2.2.14 alginate alginate PL31 poly(beta-mannuronate) lyase / M-specific alginate lyase 4.2.2.3 alginate alginate PL32 poly(beta-mannuronate) lyase / M-specific alginate lyase 4.2.2.3 host glycan hyaluronate(host glycan) PL33 hyaluronate lyase 4.2.2.1 host glycan glycosaminoglycans(host glycan) PL33 chondroitin sulfate lyase 4.2.2.20 gellan gellan(polysaccharide) PL33 gellan lyase 4.2.2.25 alginate alginate PL36 poly(beta-mannuronate) lyase / M-specific alginate lyase 4.2.2.3 host glycan glycosaminoglycans(host glycan) PL37 chondroitin-sulfate ABC endolyase 4.2.2.20 host glycan heparin sulfate(host glycan) PL37 heparin-sulfate lyase / heparin lyase III 4.2.2.8 host glycan host glycan PL38 endo-beta-1,4-glucuronan lyase 4.2.2.14 pectin rhamnogalacturonan I(pectin from the plant cell wall) PL4 rhamnogalacturonan endolyase 4.2.2.23 alginate alginate PL41 alginate lyase 4.2.2.3 arabinogalactan protein arabinogalactan PL42 L-rhamnose-α-1,4-D-glucuronate lyase 4.2.2.- arabinogalactan protein arabinogalactan PL42 L-Rhα-α-1,4-GlcA α-L-rhamnohydrolase 3.2.1.- host glycan host glycan PL5 endo-beta-1,4-glucuronan lyase 4.2.2.14 alginate alginate PL5 alginate lyase 4.2.2.3 alginate alginate PL6 poly(alpha-L-guluronate) lyase / G-specific alginate lyase 4.2.2.11 host glycan dermatan sulfate(host glycan) PL6 chondroitinase B 4.2.2.19 alginate alginate PL6 oligoalginate lyase / exo-alginate lyase 4.2.2.26 alginate alginate PL6 MG-specific alginate lyase 4.2.2.- alginate alginate PL6 alginate lyase 4.2.2.3 alginate alginate PL7 alpha-L-guluronate lyase / G-specific alginate lyase 4.2.2.11 host glycan glucuronan(host glycan) PL7 endo-beta-1,4-glucuronan lyase 4.2.2.14 alginate alginate PL7 oligoalginate lyase / exo-alginate lyase 4.2.2.26 alginate alginate PL7 poly-(MG)-lyase / MG-specific alginate lyase 4.2.2.- alginate alginate PL7 poly(beta-mannuronate) lyase / M-specific alginate lyase 4.2.2.3 host glycan hyaluronan PL8 hyaluronate lyase 4.2.2.1 xanthan xanthan PL8 xanthan lyase 4.2.2.12 host glycan glycosaminoglycans(host glycan) PL8 chondroitin ABC lyase 4.2.2.20 alginate alginate PL8 poly(beta-mannuronate) lyase / M-specific alginate lyase 4.2.2.3 host glycan glycosaminoglycans(host glycan) PL8 chondroitin AC lyase 4.2.2.5 host glycan Heparin and heparan sulfate(host glycan) PL8 heparin lyase / heparin lyase I 4.2.2.7 pectin pectate PL9 pectate lyase 4.2.2.2 pectin rhamnogalacturonan I(pectin from the plant cell wall) PL9 rhamnogalacturonan endolyase 4.2.2.23 pectin homogalacturonan(de-esterified pectin) PL9 exopolygalacturonate lyase 4.2.2.9