LOCUS CP000303 9872 bp DNA linear BCT 31-JAN-2014 DEFINITION Bifidobacterium breve UCC2003, complete genome. ACCESSION CP000303 VERSION CP000303.1 DBLINK BioProject: PRJNA13487 BioSample: SAMN02604112 KEYWORDS . SOURCE Bifidobacterium breve UCC2003 ORGANISM Bifidobacterium breve UCC2003 Bacteria; Actinobacteria; Bifidobacteriales; Bifidobacteriaceae; Bifidobacterium. REFERENCE 1 (bases 1 to 9872) AUTHORS O'Connell Motherway,M., Zomer,A., Leahy,S.C., Reunanen,J., Bottacini,F., Claesson,M.J., O'Brien,F., Flynn,K., Casey,P.G., Moreno Munoz,J.A., Kearney,B., Houston,A.M., O'Mahony,C., Higgins,D.G., Shanahan,F., Palva,A., de Vos,W.M., Fitzgerald,G.F., Ventura,M., O'Toole,P.W. and van Sinderen,D. TITLE Functional genome analysis of Bifidobacterium breve UCC2003 reveals type IVb tight adherence (Tad) pili as an essential and conserved host-colonization factor JOURNAL Proc. Natl. Acad. Sci. U.S.A. (2011) In press PUBMED 21690406 REMARK Publication Status: Available-Online prior to print REFERENCE 2 (bases 1 to 9872) AUTHORS O'Connell Motherway,M., Zomer,A., Leahy,S., Reunanen,J., Bottacini,F., Claesson,M., O'Brien,F., O'Flynn,K., Casey,P., Moreno-Munoz,J., Higgins,D.G., Shanahan,F., de Vos,W., Fitzgerald,G.F., Ventura,M., O'Toole,P. and van Sinderen,D. TITLE Direct Submission JOURNAL Submitted (27-MAR-2006) Department of Microbiology, Alimentary Pharmabiotic Centre, University College Cork, College Road, Cork, Munster, Ireland COMMENT Source DNA or strain is available from Douwe van Sinderen, d.vansinderen@ucc.ie. FEATURES Location/Qualifiers source 1..9872 /organism="Bifidobacterium breve UCC2003" /mol_type="genomic DNA" /strain="UCC2003" /db_xref="taxon:326426" gene 1..1350 /locus_tag="Bbr_0417" CDS 1..1350 /locus_tag="Bbr_0417" /codon_start=1 /transl_table=11 /product="gnl|TC-DB|P94528|3.A.1.1.34" /protein_id="ABE95115.1" /translation="MRNTKKVIAATAAVATLVGLAACGSSNDNSVNKGDADKAELVFWG WDSGNSMKEILADFEKANPGITVKFNNTGTAEKTSTALSNAIAAGNGAPDVVMLEDPTV TQFAVTDGLVDLSRFGADKLADDFAAGPWNKLQYNNKPYALPIDSGPEMFFYNKAVFDK AGVDGESIKTWDDYYEAAKKIRAIGSYITNLAGTSNDYQPFTAQIWQAGAQPWKVDGEN ITINMTKDEGMQRYIQFVQKLIDEDLVDTKTPNWSDDWNRELNDGTLASLTIGAWMPIN LMTGAPDQAGNWRVAQLPQWEDGKEVSAEDGGSALAVTSQSKNQAAAYKLVEYMTHGKG AQTMADTGTFPSLKKILKSDSFTDPTTESNKKTNDYFGGQNVNEVLSAAAQRPTEKFQY LPYNPYAQTAYGDEVSKAYSGDITLEEALQNYAKKLAEQGKQQGYNVTVK" gene 1571..2533 /locus_tag="Bbr_0418" CDS 1571..2533 /locus_tag="Bbr_0418" /codon_start=1 /transl_table=11 /product="gnl|TC-DB|D6ZW63|3.A.1.1.48" /protein_id="ABE95116.1" /translation="MSDQTMAAASQPTVGILPEEADLHTAEARVNKHKADWRGWKFMWP FTVVFVFVFIIPIVYAVYISFFKKQMIGGTRFVGVENYARLLQDGQFWSSVGRVALFTC VQVPIMLFLSAAMALALDSMKLHGAKFFRISTFLPYAVPAVVSTLVWGFVYGAKYGLVG SFNDFFGTNVDVLQPGVLLASIGNISTWEFTGYNMLIFYSSLSTIPHSLYEAASIDGAS EWQIVKSIKLPELKGSLAITVIFSIIGSFQLFNEPSILQNMVPGNAITTYYTPNMYAYN LSFSGNQSNYAAALAIVMAVITMAIAYAVQLKSMKEQMK" gene 2586..3584 /locus_tag="Bbr_0419" CDS 2586..3584 /locus_tag="Bbr_0419" /codon_start=1 /transl_table=11 /product="gnl|TC-DB|D6ZW62|3.A.1.1.48" /protein_id="ABE95117.1" /translation="MSAAASTRLTDAELKAQEKAARKAEKERQKRIAADEAAERRRSAR AGFANVSNPRRSTLMTVLCAIFAVYCLFPFVYLVINATKTQADFTSTFGLGFGKSFALW DNIVTVFTYQGGIFGRWLVNTLLYVVVGAGGATLLAIMGGYALAKFRFPGRKAVFAVII GSISVPGIALAVPQFLLFAKLGLTNTPWAMIIPSLISPFGLYLMWIFSEQAVPTELLEA ARVDGASEFRTFWTISLPLLAPGIVTTALFTIVATWNNYFLPLIMLKDADWYPLTIGLN QWKDQASTAGGQAIQNLVITGSLITIIPLVIAFLCLQKYWQSGLAAGAVKE" gene 3752..5884 /gene="lacZ4" /locus_tag="Bbr_0420" CDS 3752..5884 /gene="lacZ4" /locus_tag="Bbr_0420" /EC_number="3.2.1.23" /codon_start=1 /transl_table=11 /product="GH42" /protein_id="ABE95118.1" /translation="MTTRRAFRWPSLLTESGRGIAFGGDYNPDQWPEETLDEDIRLMGE AGVNVVSLAIFSWDKIEPVEGAFTFEWLDHVIDRLGKAGIAVDLASATATAPLWLYESH PEVLPVDRYGHIVNAGSRQSWQPTSPVFKEYALRLCRKLAERYKDNPYVTAWHMGNEYG WNNRYDYSDNALAAFRTWCEAKYGTIDALNEAWGTAFWSQHVNSFDEVLLPRHMGGDAM VNPPQQLDYERFGNDMLLDFYKAERDAIEQICPGKPFTTNFMVSTDQCVMDYAKWAGEV DFVSNDHYFHEGESHLDELACSDALMDSLALGKPWYVMEHSTSAVQWKPLNARKRAGEL MRDSLAHVAMGADAICFFQWRQSVSGAEAFHSAMLPHAGADTKVFRGVCELGKALKTLS DAGLQGTELERAGTAILFSAESEWATRSETLPSMKLNHWHDVRDWYRGFLDAGLRADVV PLAYDWTDYKTIVLPTVLSLSDEDVRRIADFAKAGGTVIVGYATGLVDEYFHIGLGGYP GAGNGLLRDMLGIRSEEFNILGEEAEGEPSEISLSNGLTTRLWQNDVTSVAADTTVLAS YTGESAADWELERTPAITSHPYGNGTAIYVGCDLNRHDIAQLLKALGSRWRELSAQPTE GGQTPTYPTTDPRILHTIRRSADGSTRFDFYLNRSNQPVAINGVEGKPIIAHRCETDAV GYTLNRNAILIAKTSC" gene 5928..6983 /locus_tag="Bbr_0421" CDS 5928..6983 /locus_tag="Bbr_0421" /codon_start=1 /transl_table=11 /product="DBD-Pfam|LacI,DBD-SUPERFAMILY|0036955" /protein_id="ABE95119.1" /translation="MSDEKTAKRRVTLRDVAQAAGVSLKTASNVINGSGRMTDETRAKV ESVIKDLDYRVNVAARNLNRNHTGFITLAVPSLIPPYLAELANRTIEAARQRNYSVYVT TYAEGSAKGARDLLKKFNSTVSDGMILSMSEVENISPDDLKVDFPLVIVGARTTWGIVD HVTPDDVSAAAMAAGYLYERGSTRLAVIGARDVYDEDALLNAVEGNAQLRLRGIIEETR RRGLSLDPQLIGNTDQDWTIGAGARVAQRLIDSGVPFDGVIALNDQLAIGALTALRTAG YEVPAQVQVIGFDNNEEAPYLQIPLTTMDSRLDWTAPTAVNRILGRIDGSIIKPELLTT ESQVIARASTR" gene 7179..9872 /gene="galA" /locus_tag="Bbr_0422" CDS 7179..9872 /gene="galA" /locus_tag="Bbr_0422" /EC_number="3.2.1.89" /codon_start=1 /transl_table=11 /product="GH53|CBM61" /protein_id="ABE95120.1" /translation="MRRNTALTRIMASSVAAIMLCAGGMFTANAAEEEPVKAAVSVKAI QGLSDDFIGGMDVSSMLSLEESGVTFKNANDEVEDLFTLLKESGVNYVRLRVWNDPFTA DGQGYGGGNVNADRALTMAKRATAAGLKVLVDFHYSDFWADPSKQQVPKAWKSFEGDVD KTADTIYDYTKQTLTTFKQAGVDVGMVQVGNETTAKIAGISGWDGMSKVFSAGSKAIRE VLPEAKVVIHFTNPEKAGTYATYAKQLSNHNVDYDVFASSYYPFWHGTTENLTSVLKNV ASTYKKDVMVAETSWAYTLDDGDDDSNTVPSKVTANNLKKYDISPQGQADEIRAVAEAV NNIGDNDGDGKNDGLGVFYWEPAWVPVGTGGKDNAELVDTWNKYGGGWATEAAGEYDPN DAGLYWGGSGVDNQALFDFDGKALASLPTFKYIHTGAVTDHVFTKIDPVEITATDSDSI DAIKAQLPSEVAAHYQDGVDETETVTWQSAALDWIRGAGTYTITGTTNAGHDVTATITV TATPAKDYVTDGNFENAENDKNWTITGTGASITEDSGNAADGKRALKFWASDAYSFSAT QTITGLEPGEYVLTAMSQGAAADNAAIADGVTLSATAGGKTTSDALELNGWVKFDTATV PVTVGADGTATITITGNLPADAWGNVDKVSLVKKTETPVKPSTENLDKAVAEAGKINRD ECTNESLAKLDQALAAADVLLAGSAYTEQDVNDVTKLVSDAIAGLAPKEVSSLTVTPSK TTYQVGDVIDADHDLKVVGNYSAGMGNVTLSADQFTLDYDFSAPADAAKVTVTLKSNPN VTETYTVAVTSRAEGGSGNGSDGAGNGGATINPDTGEGDKTNGANGGKITGVLSNTGSA VTAVGLAVVVLGVAGGVSLALRRKRS" ORIGIN 1 atgcgcaaca ccaagaaggt catcgcggca acggcagccg tggccacgct cgtcggtctc 61 gccgcctgcg gcagcagcaa cgacaacagc gtcaacaagg gtgacgccga caaggccgaa 121 ctcgtgttct ggggctggga ttccggcaac tcgatgaagg aaatcctcgc tgacttcgag 181 aaggccaacc ccggcatcac cgtcaagttc aacaacaccg gcaccgccga gaagacctcc 241 accgcgctct ccaacgccat cgccgccggc aatggcgccc cggatgtcgt gatgctcgaa 301 gatccgaccg tcacccagtt cgccgtcacc gatggcctcg tggatctgag ccggttcggt 361 gccgacaagc tcgccgacga cttcgccgcc ggcccgtgga acaagctcca gtacaacaac 421 aagccgtacg ctctgccgat tgattccggc cctgaaatgt tcttctacaa caaggcagtg 481 ttcgacaagg ccggcgtgga cggcgagtcc atcaagactt gggacgacta ctacgaggcc 541 gccaagaaga ttcgcgccat cggctcctac atcaccaacc ttgccggcac gtccaacgac 601 taccagccct tcaccgccca gatctggcag gccggcgccc agccgtggaa ggtcgatggc 661 gagaacatca ctatcaacat gaccaaggac gagggcatgc agcgctatat ccaattcgtc 721 cagaagctca tcgacgaaga cctcgtggac accaagaccc cgaactggtc cgatgattgg 781 aaccgcgagc tcaacgatgg caccctcgcc tccctgacca tcggcgcttg gatgccgatc 841 aacctcatga ccggcgcccc cgatcaggcc ggcaactggc gcgtcgccca gctgccgcag 901 tgggaggacg gcaaggaagt ctccgccgaa gacggtggct ccgcacttgc cgtcacctcg 961 cagtccaaga accaggccgc tgcctacaag ctcgttgagt acatgactca tggcaagggc 1021 gctcagacca tggccgacac cggtaccttc ccgtccctga agaagatcct gaagtccgac 1081 tccttcaccg acccgaccac cgagtccaac aagaagacca acgactactt cggcggtcag 1141 aacgtcaacg aagtcctttc cgccgcggct cagcgcccga ccgagaagtt ccagtacctg 1201 ccgtacaacc cgtacgccca gaccgcttac ggcgacgaag tctccaaggc ctactccggc 1261 gacatcaccc tggaggaagc actccagaac tacgccaaga agctggccga gcaaggcaag 1321 cagcagggct acaacgtcac cgtcaagtga cacaatccga tctattgccg gtacatccgg 1381 cactgaccaa caatcaaaac ctgcggctag gccactctcc ttccgcctag ccgcccgatc 1441 tcccacagcg gggatgctcc ccagtgtccc cgctttccca tgccctcacc tgacgtgacc 1501 gctccaatcg agcgaccccc ctgatagcgg gcgcagcaca gcaatccgta tcccaagaaa 1561 gcaatcgatt atgtccgatc aaacaatggc cgcagcctcg cagccaacgg tgggaatcct 1621 gcctgaggag gcggatctgc acacggccga ggcccgcgtc aacaagcata aggccgattg 1681 gcgtggatgg aagttcatgt ggccgttcac ggtggtgttc gtgttcgtgt tcattattcc 1741 gattgtgtac gccgtttaca tcagcttctt caagaagcag atgatcggcg gcacgaggtt 1801 cgtcggggtc gagaactacg cgcgtctgct gcaggacggc cagttctggt cgtccgtggg 1861 tcgtgtggcg ctgttcacct gcgtgcaggt gccgatcatg ctgttcctgt cggctgccat 1921 ggccctcgcc ctggattcga tgaagctgca cggtgccaag ttcttccgca tcagcacgtt 1981 cctgccctat gcggtgcccg cagtggtgtc cacgttggtg tggggcttcg tgtacggcgc 2041 gaagtacggc ctggtgggct cgttcaacga cttcttcggc acgaacgtcg acgtgctgca 2101 gccgggcgtg ctgcttgcct ccatcggcaa catcagcacg tgggagttca ccggctacaa 2161 catgctgatc ttctactcgt cgctgtccac catcccgcac tccctgtacg aggccgcctc 2221 catcgacggc gcctccgaat ggcagatcgt caagtccatc aagctgcccg agctgaaggg 2281 ctcgctggcc atcacggtga tcttctcgat catcggcagc ttccagctgt tcaacgagcc 2341 gagcatcttg cagaacatgg ttccgggcaa cgcgatcacc acgtactaca cgccgaacat 2401 gtacgcgtac aacctgagct tctccggcaa ccagtcgaat tacgcggccg ctctggccat 2461 cgtgatggcc gtcatcacca tggccatcgc ctacgccgtg cagctgaaga gcatgaagga 2521 gcagatgaag tgacgacgac cgcccgtatt gccggattgg tttcgattgt gaaggagcgt 2581 gcgtgatgag tgccgcagca tctacccgtc tgactgacgc cgaactgaag gcgcaggaga 2641 aggccgccag gaaggccgag aaggaacgcc agaagcgcat cgccgccgat gaggcggccg 2701 agcgcaggcg cagcgccagg gccggtttcg cgaacgtgag caacccgcgc cgttcgaccc 2761 tgatgaccgt gctgtgcgcg atcttcgccg tgtactgcct gttcccgttc gtgtacctgg 2821 tgatcaacgc caccaagacc caggccgact tcacctccac gttcggcctc ggcttcggca 2881 agagcttcgc cctgtgggac aacatcgtca cggtgttcac ctaccagggc ggcatcttcg 2941 gccgctggct ggtcaacacc ctgctctacg tggtcgtcgg cgccggcggc gccaccctcc 3001 tggccatcat gggcggctac gcgctggcca agttccgctt cccgggccgc aaggccgtgt 3061 tcgccgtgat catcggctcg atctccgtgc cgggcatcgc cctggccgtg ccgcagttcc 3121 tcctgttcgc caagctgggc ctgaccaaca ccccgtgggc catgatcatc ccgtcgctga 3181 tctccccgtt cggcctgtac ctgatgtgga tcttcagcga gcaggccgtg cccaccgagc 3241 tcctggaggc cgcccgcgtg gacggcgcgt ccgagttccg cacgttctgg accatcagcc 3301 tgccccttct ggcccccggt atcgtgacga ccgccctgtt cacgatcgtg gcgacgtgga 3361 acaactactt cctgccgttg atcatgttga aggacgccga ctggtacccg ctgaccatcg 3421 gtctgaacca gtggaaggac caggcttcga ccgcgggcgg ccaggccatc cagaacctgg 3481 tgatcaccgg ctccctgatc acgatcatcc cgctggtcat cgcgttcctg tgcctgcaga 3541 agtactggca gtccggcctc gccgcaggcg ccgtcaagga gtagttgcta ctccctctga 3601 ctctcctcag agaggggagc tggagaaatg gggtcttggc ttccctctct gaggagagct 3661 gtcgaacgca gtgagactga ggggagccaa agcccaaaac cggcaaacac agcaccggcc 3721 atgagccgat acaataaagg atttgattaa tatgactact cgtagagcat ttaggtggcc 3781 gtccctgctg acggaatccg gccgcggcat cgcgttcggc ggcgactaca acccggacca 3841 gtggcccgag gagacgttgg acgaggatat ccgtctcatg ggtgaggccg gcgtgaacgt 3901 cgtatcgctg gcaatcttca gctgggacaa gatcgagccg gtcgagggcg cgttcacgtt 3961 cgagtggctc gaccatgtga tcgacaggct cggcaaagcc ggcatcgccg tggacttggc 4021 ctccgctacc gccaccgcgc cgctgtggct gtacgaatcc catccagagg tgctgccggt 4081 agaccggtat ggtcatatcg tcaacgcggg ctcacgccag tcgtggcagc ccacaagccc 4141 ggtgttcaag gaatacgcgc tgcgcctgtg ccgcaaactt gctgaacgct acaaggacaa 4201 cccgtatgtg accgcctggc acatgggcaa cgaatacggc tggaacaacc gctacgacta 4261 ctccgacaac gccttggccg cgttccgcac gtggtgcgag gccaagtacg gtaccatcga 4321 cgcgttgaac gaggcgtggg gcacggcctt ctggtcgcag cacgtgaaca gtttcgacga 4381 ggtgttgctg ccgcgtcaca tgggcggcga tgccatggtc aacccgccgc agcagctcga 4441 ctatgagcgg ttcggcaacg acatgctgct cgacttctac aaggccgaac gtgacgctat 4501 cgagcagatc tgccccggca agccgttcac cacgaacttc atggtctcca ccgaccagtg 4561 cgtcatggac tacgccaaat gggccggcga ggtggacttc gtgtccaacg accactactt 4621 ccatgaaggc gaatcccact tggacgagct cgcctgctcg gacgcgctca tggactccct 4681 cgcgctgggc aagccgtggt acgtgatgga gcactccacc tcagccgtgc agtggaagcc 4741 gctcaacgcg cgcaaacggg ccggcgaact tatgcgcgac tccctggccc acgtggccat 4801 gggcgccgac gccatctgct tcttccaatg gcggcagtcc gtgtccggcg ccgaggcgtt 4861 ccactccgcc atgctgcccc acgcgggcgc cgacacgaag gtcttccgcg gcgtatgcga 4921 gctcggcaag gcgctgaaga ctctctccga cgccgggctg cagggcactg agctcgagcg 4981 tgccggcaca gcgatcctgt tcagcgcgga atccgaatgg gccacacgct ccgaaaccct 5041 gcccagcatg aaactcaacc attggcacga cgttcgcgac tggtaccgcg gcttcctgga 5101 tgccgggctg cgcgcggacg tggtgccgct cgcctacgac tggactgact acaaaaccat 5161 cgtgctgccc accgtgctca gcctgtccga cgaagacgtt cgccgtatcg ccgacttcgc 5221 gaaggccggc ggaaccgtca tcgtcggcta cgccactggc ctggtcgacg agtacttcca 5281 catcgggctc ggcggatacc caggtgccgg caatggcctc ctacgcgaca tgctcggcat 5341 ccgcagcgaa gaattcaaca tcctcggtga agaagccgaa ggcgagccca gcgaaattag 5401 cctgtccaac ggtctgacga cccgcctgtg gcagaacgac gtgacttccg tagccgcgga 5461 caccacagtg ctcgcctctt acacaggtga gtccgccgcc gactgggagc tggagcgcac 5521 ccccgccatc accagccacc cctatggcaa cggtaccgcc atctacgtgg gctgcgacct 5581 caaccgtcat gacattgccc agctgctcaa agcacttggc tcccgctggc gggagctgtc 5641 ggcgcagccg actgagggtg gtcaaactcc aacctatccc accacagatc cccgcatcct 5701 gcacaccatc cgccgatccg cagacggctc cacccgcttc gatttctacc tcaaccgctc 5761 aaaccagccc gtcgccatca acggtgtgga aggcaagccc atcatcgccc accgttgcga 5821 gacggatgcc gtcggatata cgctgaaccg taacgctatt cttatcgcta aaacgtcctg 5881 ctagaccgcg ttagaatggc aatgttgtcc ggatggagga gcgcggcatg agcgacgaga 5941 aaacagccaa gcgtcgagtg acgctacgcg atgtcgctca ggccgccggt gtatcgctca 6001 aaactgcgtc gaacgtgatc aatggctccg gacgtatgac cgatgagacc cgtgccaagg 6061 tcgagtcggt cattaaggac ctcgactacc gagtcaatgt ggccgcccgc aacctcaacc 6121 gcaatcacac cggtttcatc acccttgccg tgccttcgct gattccgcca tatctggccg 6181 agttggccaa ccgcaccatc gaggccgccc gccagcgcaa ctattccgta tacgtcacca 6241 cgtatgcgga aggctccgcg aaaggcgcgc gcgatctgct gaagaagttc aactccacgg 6301 tgtccgatgg catgatcctt tccatgagcg aggtggaaaa catttcgccc gatgatctga 6361 aggttgattt tccgctggtc atcgttggcg cgcgtaccac gtggggcatt gtggatcacg 6421 tgaccccaga cgatgtatcc gcagccgcca tggccgcagg ctacctgtat gagcgcggtt 6481 ccaccagact tgcagtgatc ggtgcccgtg acgtttacga cgaagatgca ttgctgaatg 6541 ccgtagaagg caacgcgcag ctgcgtctgc gcggcatcat cgaagagacc cgcaggcgtg 6601 ggctctcctt ggatccgcag ctgattggca acaccgatca ggattggacc atcggagccg 6661 gtgcccgtgt ggcccagcgg ctcattgatt ccggcgtgcc gttcgacggt gtgatcgccc 6721 tgaacgatca gttggccatc ggcgcattga ccgctctgcg caccgctggt tatgaggtgc 6781 ccgcgcaggt gcaggtcatc ggcttcgata acaacgagga agccccctac ctgcagattc 6841 cgctgaccac catggattcc cgccttgact ggacggctcc cacggcagtg aatcgcatcc 6901 tcggacgcat cgacggcagc atcatcaagc ccgaactgct caccaccgaa tcccaagtca 6961 tcgcccgcgc ctccacgcgt tgaacgacat tgctgtaatg ctggtgttgc tgtactgggc 7021 cgtacgaggc gatgatacac cggttgacca acgcggtata aagtgttaag gtgacaattg 7081 cgtgatacac agctgtacca cgtggcgcat aaggaaagga agcgccaagc atcactgggc 7141 gttcgttctg agcgttcacc attcaaagga gaaaaagcat gcgccgaaat accgcgctta 7201 ctcgcattat ggcatccagc gtggccgcca taatgctctg cgcaggaggc atgttcactg 7261 caaacgccgc cgaagaagaa ccagtcaaag ccgccgtctc ggtcaaggcc atccaaggct 7321 taagcgatga tttcatcggt ggtatggacg tctcatccat gctctcgctg gaagaaagcg 7381 gcgtcacgtt caagaacgcc aatgacgagg tcgaggattt gttcacgctg ctcaaggaat 7441 ccggcgtgaa ctatgtgcgt ctgcgcgtgt ggaacgatcc gttcaccgca gacggccaag 7501 gatatggcgg cggcaacgtc aacgccgatc gcgcactgac catggccaag cgagccacgg 7561 cagcagggct gaaagtgctg gtcgacttcc attactccga tttctgggcc gaccccagca 7621 agcagcaggt gcccaaggcg tggaaatcct ttgaaggcga cgtggacaaa accgccgaca 7681 ccatatacga ctacaccaag cagacgctga ccacgttcaa acaagccggc gtagacgtcg 7741 gcatggtgca ggtcggcaac gaaaccactg cgaaaatcgc cggcatctcc ggctgggacg 7801 gcatgtccaa agtattctcc gcaggctcca aagccatacg cgaagtgctc cccgaagcca 7861 aggtcgtcat tcatttcacc aacccggaga aagccggcac ctacgccact tatgccaaac 7921 agttgagcaa ccacaatgtg gattacgatg tgttcgccag ctcctactac ccgttctggc 7981 atggcaccac cgaaaacctc accagcgtgc tcaagaacgt ggcctccact tataagaaag 8041 atgtgatggt ggcggaaacg tcgtgggcat acaccttgga tgatggtgac gacgattcca 8101 acacagtgcc cagtaaagta accgccaata acctcaagaa atacgacatc agtccgcaag 8161 gccaggccga tgagattcgc gcggtcgccg aggccgtgaa caatattggc gacaatgatg 8221 gcgatggcaa aaacgacggc ctgggtgtgt tctactggga gcccgcatgg gtgcccgtgg 8281 gcaccggcgg caaggataac gccgagctgg tggatacgtg gaacaagtac ggtggcggct 8341 gggccactga agcggccggc gaatacgatc ccaatgacgc cggcctgtac tggggcggct 8401 caggtgtcga taaccaagct ttgttcgatt tcgatggtaa ggcgctcgcc tctctgccga 8461 cgttcaagta catccacacc ggtgccgtca ccgatcatgt gttcaccaag atagatccag 8521 tggagattac cgcgactgac tcggattcca tcgacgcgat caaagcgcaa ttgccgagtg 8581 aagtggctgc acactatcag gatggggtgg acgagaccga aaccgtgacc tggcaatccg 8641 ctgcgcttga ctggattcgt ggcgcaggca catacaccat caccggcacc accaacgctg 8701 gccacgacgt gaccgccacc atcaccgtca ccgccactcc cgccaaggat tacgtaacgg 8761 acggcaactt cgagaacgct gaaaacgata agaactggac cattaccggc accggtgcgt 8821 ccatcaccga agacagtggc aacgccgccg acggcaagcg cgcgctgaag ttttgggcat 8881 ccgatgccta cagtttctcc gccacgcaga ccattaccgg actcgagcct ggcgaatacg 8941 tactgaccgc catgagccaa ggcgcggcag cggacaacgc cgctattgcc gatggtgtga 9001 ccctctccgc cacagcgggt ggcaagacca cgtccgatgc gctggaactc aacggttggg 9061 ttaagttcga taccgccacc gtgcctgtca ctgtgggtgc tgatggcaca gcgaccatca 9121 ccatcacggg caacctgcct gccgacgcat ggggcaatgt ggacaaggtc tcactcgtca 9181 aaaagaccga aactccggtg aagccatcca cggagaacct ggacaaggcc gtggccgaag 9241 ccgggaaaat caatcgcgat gagtgcacca acgagtcgct cgccaaactc gatcaggcgc 9301 ttgccgccgc tgacgtgctg cttgccggca gcgcctacac cgagcaagac gtgaacgatg 9361 tgactaagct tgtttccgat gccattgccg gcctcgcccc aaaggaggtc tccagcctga 9421 ccgtcacgcc aagcaaaacc acctatcagg tgggcgatgt catcgatgcc gaccatgatc 9481 tcaaggtcgt gggcaactat tccgcaggca tgggcaacgt gacgctttcc gccgaccagt 9541 tcacgctcga ttacgatttc tccgctcccg ctgatgcggc gaaggttacc gtaacgctca 9601 agtcgaatcc gaatgtcacc gaaacctata cggttgctgt tacctctcgg gccgaaggtg 9661 gttccggcaa cggctcggac ggtgcgggta atggcggggc tactatcaat cccgatacgg 9721 gcgagggcga taagaccaac ggtgcgaatg gcggcaagat cactggtgtg ctgagcaata 9781 ccggtagcgc ggtgactgcc gtgggtcttg cggttgtcgt tctcggcgtg gccggcgggg 9841 tctcgcttgc tttgcgtcgt aagcgctcct ga //