Browse anti-prokaryotic immune system families by Defense system

AD families AD genes Defense system CLAN ID Phages/MGEs References Description
APIS091 HOS17_gp01 restriction-modification (RM);bacteriophage exclusion (BREX) CLAN042 T3 of E. coli Andriianov et al., 2023 T3 encodes a SAMase that circumvents the SAM-dependent Type I R-M defence of the host E. coli through cleavage of S-adenosyl-methionine (SAM). SAMase also allows T3 to evade BREX defence.
APIS093 CLAN042 Pantoea phage vB_PagP-SK1
APIS148 OrbA bacteriophage exclusion (BREX) CLAN085 Vibrio phage ICP1 PMID:34326207 Clinical phage ICP1 overcomes cocirculating SXT ICEs through acquisition of epigenetic RM as well as an anti-BREX protein, OrbA.
anti_TerI2 anti_TerI2 TerI CLAN110 Listeria monocytogenes 10403S Azulay et al., 2025 Anti-TerI2 counteract TerI during prophage induction to allow virion production.
APIS265 anti_TerI1 TerI CLAN053 Listeria monocytogenes 10403S Azulay et al., 2025 Anti-TerI1 counteract TerI during prophage induction to allow virion production.
APIS324 CLAN053