| Basic Information | |
|---|---|
| Species | Panicum virgatum |
| Cazyme ID | Pavirv00018845m |
| Family | GT4 |
| Protein Properties | Length: 420 Molecular Weight: 46531 Isoelectric Point: 8.2213 |
| Chromosome | Chromosome/Scaffold: 051142 Start: 952 End: 4513 |
| Description | UDP-Glycosyltransferase superfamily protein |
| View CDS | |
| External Links |
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| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT4 | 224 | 387 | 1.2e-39 |
| FLSINRFERKKNLDLAISAFALLRSVASKLPGDALQDATLTVAGGYDKRLKENVDYLEELKRLAVTEGVSGQVKFVTSCSTSERNELLSNCLCVLYTPKD EHFGIVPLEAMAAHKPVITCNSGGPVETVVNEVTGFLCDPSPTEFSKAMLKLVNDHDLAIRMGK | |||
| Full Sequence |
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| Protein Sequence Length: 420 Download |
| MVAAGGGAGC SSPSVTRARK LKVAVIHPDL GIGGAERLIV DVASQLAAHG YDVHVFTSHH 60 DKNRCFEETV SGPFLVTVYG DFLPRHVFYR FHAVCAYLRC IFVALCVLLW WPSFDVILVD 120 QVSVVIPLLK LKASTKIVFY CHFPDLLLAQ HTTMLQRLYR KPIDMIEEAT TGMANLILVN 180 SKFTAATFAR TFRGLHARGI EPRVLYPVVS AEQFHEPHSY KLNFLSINRF ERKKNLDLAI 240 SAFALLRSVA SKLPGDALQD ATLTVAGGYD KRLKENVDYL EELKRLAVTE GVSGQVKFVT 300 SCSTSERNEL LSNCLCVLYT PKDEHFGIVP LEAMAAHKPV ITCNSGGPVE TVVNEVTGFL 360 CDPSPTEFSK AMLKLVNDHD LAIRMGKQAR DHVVQKFSTK TFGGLLNSYV LNVYHERME* 420 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd03798 | GT1_wlbH_like | 9.0e-34 | 27 | 398 | 391 | + This family is most closely related to the GT1 family of glycosyltransferases. wlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core (band B), generates band A LPS. | ||
| COG0438 | RfaG | 4.0e-36 | 19 | 417 | 406 | + Glycosyltransferase [Cell envelope biogenesis, outer membrane] | ||
| cd03811 | GT1_WabH_like | 4.0e-37 | 22 | 398 | 391 | + This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core. | ||
| cd03801 | GT1_YqgM_like | 1.0e-48 | 22 | 398 | 390 | + This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea. | ||
| cd03805 | GT1_ALG2_like | 0 | 21 | 404 | 397 | + This family is most closely related to the GT1 family of glycosyltransferases. ALG2, a 1,3-mannosyltransferase, in yeast catalyzes the mannosylation of Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. A deficiency of this enzyme causes an abnormal accumulation of Man1GlcNAc2-PP-dolichol and Man2GlcNAc2-PP-dolichol, which is associated with a type of congenital disorders of glycosylation (CDG), designated CDG-Ii, in humans. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0009058 | biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | ACU21459.1 | 0 | 20 | 414 | 8 | 402 | unknown [Glycine max] |
| GenBank | EAY95346.1 | 0 | 13 | 419 | 12 | 418 | hypothetical protein OsI_17177 [Oryza sativa Indica Group] |
| RefSeq | NP_001053699.1 | 0 | 13 | 419 | 12 | 418 | Os04g0589600 [Oryza sativa (japonica cultivar-group)] |
| RefSeq | XP_002317454.1 | 0 | 19 | 413 | 3 | 407 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002447012.1 | 0 | 14 | 419 | 13 | 418 | hypothetical protein SORBIDRAFT_06g026860 [Sorghum bicolor] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2f9f_A | 2e-19 | 224 | 380 | 26 | 164 | A Chain A, Crystal Structure Of The Putative Mannosyl Transferase (Wbaz-1)from Archaeoglobus Fulgidus, Northeast Structural Genomics Target Gr29a |
| PDB | 2jjm_L | 0.0000002 | 309 | 400 | 280 | 372 | A Chain A, Crystal Structure Of A Family Gt4 Glycosyltransferase From Bacillus Anthracis Orf Ba1558. |
| PDB | 2jjm_K | 0.0000002 | 309 | 400 | 280 | 372 | A Chain A, Crystal Structure Of A Family Gt4 Glycosyltransferase From Bacillus Anthracis Orf Ba1558. |
| PDB | 2jjm_J | 0.0000002 | 309 | 400 | 280 | 372 | A Chain A, Crystal Structure Of A Family Gt4 Glycosyltransferase From Bacillus Anthracis Orf Ba1558. |
| PDB | 2jjm_I | 0.0000002 | 309 | 400 | 280 | 372 | A Chain A, Crystal Structure Of A Family Gt4 Glycosyltransferase From Bacillus Anthracis Orf Ba1558. |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| dolichyl-diphosphooligosaccharide biosynthesis | RXN-5462 | EC-2.4.1.132 | GDP-Man:Man1GlcNAc2-PP-Dol α-1,3-mannosyltransferase |
| dolichyl-diphosphooligosaccharide biosynthesis | RXN-5463 | EC-2.4.1.257 | GDP-Man:Man2GlcNAc2-PP-Dol α-1,6-mannosyltransferase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| GO874725 | 342 | 14 | 352 | 0 |
| GO851037 | 297 | 14 | 310 | 0 |
| GO848903 | 321 | 14 | 331 | 0 |
| CN129110 | 270 | 14 | 283 | 0 |
| GO865623 | 277 | 14 | 290 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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