CAZyme Information: MGYG000004869_04518

Basic Information

• Species: Lactonifactor sp009677585
• Lineage: Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Lactonifactor; Lactonifactor sp009677585
• CAZyme ID: MGYG000004869_04518
• CAZy Family: GH146
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1729	MGYG000004869_69|CGC1	192538.04	4.4731

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000004869	4923116	Isolate	United States	North America

• Gene Location: Start: 25900; End: 31089 Strand: -

Full Sequence      

MRKKKKIATQSTAFVLTGVMLAGSILPSLPVYAESDILALLNESKTLEMSFDGTLEDKVL
TDRSVLARGQDGGEKEAVYTEGVSGEALQLDGATYIDLGTEQDIQPENLTASVWVKANAA
LSGEQLITWNKGAYNEDGWYLNTTDNNPLFLSVGTAVSGSQPQEYYVEGKRSEFFPAGEW
VHVAVTYNAETQEAAMYRNGEKLTVKAKYNSSSGIHGSDCTKTLGNNGTVHNGGCSNISL
DEYAVYSAVADDAQVQELYKLYADTSGEGEEPDPSFTEERVLNLAFDGDTTDTSEKKHPV
TIVGENYGYIQGAAEGTQALELKGKTYVDLGTDASLNPSSLTFSFWVNPTQDMGGGEHLF
VWNKEAYYSDGWYLSSENKDKPLSISIGSSNDWKQPYKVGVEADRSEFFPVGEWTHIAVS
FDDTTKEVTMYRNGIRQKVTVFSPIGTDGADGTIDQGNEMKKALGYNGPVHNSTYGIFAM
DNVALLNHASTQDEVLELFEETQAFDRQTLVDADAEALSLPAYTRKDLELPDKGTNGSTI
TWESSRKDIITDDGKVTLPEDADAEVTMTAHLAYGKDYTAVKECKVVVSAANWNLTNNGM
DKVTLSDSYLVNAQQKEYDYLLSMSSNKFLYEFYRVAGLDPLTDSGYGGWERSNDTNFRG
HTFGHYMSALSQAYLGCKDEATKTALLEQMSDAVAGLKECQDSYGTTHPESKGYISAFRE
SALDAVQGSGGTDENVLVPWYNLHKVLAGLIDIAKNVDGQVGEEALEVAMGFGDYIYTSR
TSTWTDAQKKRMLTIEYGGMNEALYELYNITGNPDYKSAAECFDETELFVQLSQGKDVLN
GKHANTTIPKFIGALKRYTVLTQERYYGELTQEEKDNLEMYLTAAENFWDIVVKDHTYIT
GGNSESEHFHAAGSLGQYANNRTCETCNTYNMLKLSRALFQVTGDVKYMDYYENTYINAI
LSSQNPETGMSMYFQPMAPGYYKLYSSPYDSFWCCTGTGMENFTKLGDTIYLKKGNQLFV
NMFFSSAYTDSEFQISQEANIPNSDKVSFTVAAVPEGGAVMVRKPDWLAGKAAVTINGTA
SELKVTDSYYQLDGLKAGDKVEITLPMEVQVYEMPDDSSMVAFRYGPVALSTGLGTNNMD
QREGAGIIVYAPVLDKSAADTITMTDEKVEDWKAGIKENLVRIEDTEDGQVQFALRGTDQ
DDKLFYTPHYLRYNERYGLYMNLSEPDSEKYQQKLLESKETLREKESSSAYLTNFDNNNS
EFSLGLKHSENSEVGTYGGRQYRHAEKDGWFSYELPVNKEAGKNYLFTTYYGGDKGRSFD
IYINGEKFVTETLSDTEYPLTSDGFYTVKREIPGKYLEGDSITVKFQSTGGFVGGLFGVS
VGTDYDTNAELKQLSFDMGELSPEFKGDVKEYTLTVPRDSKSVRMTAVPIKASGLVYDGE
VLFDDTKARLVKLEGDATEILLTSKAQDHKSLTQYTIHVVKGDVEEKKEGWQQDGDRWLY
MKEDGTYVEDDWKLIDGKWYHFDKSGYMQTGWLQLGSTWYYLKSSGAMATGWLQLGTTWY
YLKSSGAMATGWLQLGSTWYYLKSSGAMATGWLLDGKTWYYLKSSGAMATGWLQLGSTWY
YLKSNGAMVTGWLLDGKTWYYLKSSGAMATGWLLDGKTWYYLKSNGAMATGWLLDGKTWY
YLKSNGAMATGWLKDGSRWYYLRDNGAMASNTWIGKYYVNKSGVWTRTR

Enzyme Prediction     

No EC number prediction in MGYG000004869_04518.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH146	603	1130	5.9e-176	0.9940357852882704

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam07944	Glyco_hydro_127	6.23e-124	603	1131	2	503	Beta-L-arabinofuranosidase, GH127. One member of this family, from Bidobacterium longicum, UniProtKB:E8MGH8, has been characterized as an unusual beta-L-arabinofuranosidase enzyme, EC:3.2.1.185. It rleases l-arabinose from the l-arabinofuranose (Araf)-beta1,2-Araf disaccharide and also transglycosylates 1-alkanols with retention of the anomeric configuration. Terminal beta-l-arabinofuranosyl residues have been found in arabinogalactan proteins from a mumber of different plantt species. beta-l-Arabinofuranosyl linkages with 1-4 arabinofuranosides are also found in the sugar chains of extensin and solanaceous lectins, hydroxyproline (Hyp)2-rich glycoproteins that are widely observed in plant cell wall fractions. The critical residue for catalytic activity is Glu-338, in a ET/SCAS sequence context.
NF033930	pneumo_PspA	6.44e-94	1512	1725	445	659	pneumococcal surface protein A. The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus.
COG3533	COG3533	3.69e-89	602	1130	11	500	Uncharacterized conserved protein, DUF1680 family [Function unknown].
NF033930	pneumo_PspA	7.97e-87	1529	1723	442	640	pneumococcal surface protein A. The pneumococcal surface protein proteins, found in Streptococcus pneumoniae, are repetitive, with patterns of localized high sequence identity across pairs of proteins given different specific names that recombination may be presumed. This protein, PspA, has an N-terminal region that lacks a cross-wall-targeting YSIRK type extended signal peptide, in contrast to the closely related choline-binding protein CbpA which has a similar C-terminus but a YSIRK-containing region at the N-terminus.
NF033838	PspC_subgroup_1	5.31e-83	1529	1725	485	682	pneumococcal surface protein PspC, choline-binding form. The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ARK06383.1	0.0	281	1482	47	1293
QJW37681.1	0.0	272	1482	44	1293
AEI10685.1	0.0	281	1481	41	1291
QUB98427.1	0.0	281	1482	47	1293
QDP74899.1	0.0	281	1482	47	1293

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6YQH_AAA	1.07e-91	592	1370	22	788	ChainAAA, Acetyl-CoA carboxylase, biotin carboxylase [Bacteroides thetaiotaomicron VPI-5482]
5OPJ_A	1.02e-86	592	1370	22	788	Beta-L-arabinofuranosidase[Bacteroides thetaiotaomicron]
4IWT_A	2.03e-06	1490	1528	5	43	Crystalstructure of the C-teminal choline-binding domain of the Streptococcus pneumoniae prophage LytA [Streptococcus pneumoniae GA60080],4IWT_B Crystal structure of the C-teminal choline-binding domain of the Streptococcus pneumoniae prophage LytA [Streptococcus pneumoniae GA60080]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000383	0.998831	0.000222	0.000207	0.000168	0.000149

TMHMM  Annotations     

start	end
13	32