CAZyme Information: MGYG000004612_01308

Basic Information

• Species: UMGS363 sp900768245
• Lineage: Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; UMGS363; UMGS363 sp900768245
• CAZyme ID: MGYG000004612_01308
• CAZy Family: GH2
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
893		99412.74	4.6445

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000004612	2741718	MAG	France	Europe

• Gene Location: Start: 11530; End: 14211 Strand: -

Full Sequence      

MINSISLSGNWKLHIETECGGIPAAYEDSIDLPDTLSNAKKAPYTDWKADGFLTDAYPYE
GYAWFSRTIEVNDDYSDKNVFLFLERTRISTVYVDGCRVGSFNSLCSAHSYNIGSYLTKG
RHELVICVSNVNYPTKGGHMTSPDTQTNWLGITGKLELQIFPKTYISDVRITAGSDGIVK
VSGCINGAENGSVKASVSAPDESVVYSGDISCCGEKFSGEIKIDSPLLWDEFDRNIYTLR
LEAMGDTYSASFGFRTFSNEGRKLLINGSEAFLRGKHDGLIWPLTGYAPCDVDSWVKRLG
IAKNYGINHYRFHTCCPPDAAFTAADMVGIYMEPELPFWGTIAGKGEEGYNEEEQEYLIS
EGKRIIAEFSHHPSFVMMSLGNELWGSRERLGEIISILREGDPSIYFTSGSNNFQFWPAE
IPEEDFFTGVRLSKDRLFRGSYATCDAPLGHIQTDAPNTSHNYDDIISGKAGSDEQNGGT
IQIQYGTGVKTVSVSAADGSYIPNKPVISHEVGQYDFFPDFDEASRYTGPLKPRYLDIFR
ETLEKRSLFGQWRDFYKAVGALCTDCYKNEIETALRSKELSGFQLLDLQDFNGQGVSLVG
ILNALMESKGFITPEAWRGFCDSSVLLAEMDKYVFSSKEDLNVSFLLSSYGSEKVKSGTM
TYHLKGSEINEKGCIDFTANDERLTKIGSASISLKAVSVPQKAVLTLESGKMKNSYDLWL
YPETDVVITENGMSYNGSTVKFVRDIETAKAAIAEGEKALVISDGSNSIENTYCADFWNY
HMFRVISESMNKPVAPGTMGLLIDNENNLLKDFPSEKYSTPQWFELVMHSVADVLDDCPD
IKPVVQVVDNTERCHRLGMLYQKDGVTVCTVRLWEISDKAEVRQFAKNLIINL

Enzyme Prediction     

No EC number prediction in MGYG000004612_01308.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH2	4	420	4.1e-58	0.4853723404255319

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
PRK10150	PRK10150	2.24e-21	6	404	14	442	beta-D-glucuronidase; Provisional
COG3250	LacZ	2.95e-17	5	384	13	407	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
pfam00703	Glyco_hydro_2	3.20e-08	164	255	1	106	Glycosyl hydrolases family 2. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.
pfam02836	Glyco_hydro_2_C	0.002	260	404	4	155	Glycosyl hydrolases family 2, TIM barrel domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.
pfam02837	Glyco_hydro_2_N	0.002	6	130	3	135	Glycosyl hydrolases family 2, sugar binding domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities and has a jelly-roll fold. The domain binds the sugar moiety during the sugar-hydrolysis reaction.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CBL34265.1	0.0	1	892	1	893
CBK95918.1	0.0	1	892	1	893
BAV13119.1	3.38e-289	1	885	1	905
ADL53165.1	3.38e-289	1	885	1	905
QAA34542.1	1.25e-274	1	890	1	910

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6D89_A	1.01e-19	6	391	38	421	Bacteroidesuniformis beta-glucuronidase 1 with N-terminal loop deletion [Bacteroides uniformis],6D89_B Bacteroides uniformis beta-glucuronidase 1 with N-terminal loop deletion [Bacteroides uniformis],6D89_C Bacteroides uniformis beta-glucuronidase 1 with N-terminal loop deletion [Bacteroides uniformis],6D89_D Bacteroides uniformis beta-glucuronidase 1 with N-terminal loop deletion [Bacteroides uniformis]
6D1N_A	4.21e-19	6	391	38	429	Apostructure of Bacteroides uniformis Beta-glucuronidase 1 [Bacteroides uniformis],6D1N_B Apo structure of Bacteroides uniformis Beta-glucuronidase 1 [Bacteroides uniformis],6D41_A Bacteriodes uniformis beta-glucuronidase 1 bound to D-glucaro-1,5-lactone [Bacteroides uniformis],6D41_B Bacteriodes uniformis beta-glucuronidase 1 bound to D-glucaro-1,5-lactone [Bacteroides uniformis],6D6W_A Bacteroides uniformis beta-glucuronidase 1 bound to glucuronate [Bacteroides uniformis],6D6W_B Bacteroides uniformis beta-glucuronidase 1 bound to glucuronate [Bacteroides uniformis],6D6W_C Bacteroides uniformis beta-glucuronidase 1 bound to glucuronate [Bacteroides uniformis],6D6W_D Bacteroides uniformis beta-glucuronidase 1 bound to glucuronate [Bacteroides uniformis],6D7F_A Bacteroides uniformis beta-glucuronidase 1 bound to thiophenyl-beta-D-glucuronide [Bacteroides uniformis],6D7F_B Bacteroides uniformis beta-glucuronidase 1 bound to thiophenyl-beta-D-glucuronide [Bacteroides uniformis],6D7F_C Bacteroides uniformis beta-glucuronidase 1 bound to thiophenyl-beta-D-glucuronide [Bacteroides uniformis],6D7F_D Bacteroides uniformis beta-glucuronidase 1 bound to thiophenyl-beta-D-glucuronide [Bacteroides uniformis],6D7F_E Bacteroides uniformis beta-glucuronidase 1 bound to thiophenyl-beta-D-glucuronide [Bacteroides uniformis],6D7F_F Bacteroides uniformis beta-glucuronidase 1 bound to thiophenyl-beta-D-glucuronide [Bacteroides uniformis]
3GM8_A	7.80e-16	4	413	6	427	ChainA, Glycoside hydrolase family 2, candidate beta-glycosidase [Phocaeicola vulgatus ATCC 8482]
7VQM_A	2.59e-13	4	391	13	417	ChainA, GH2 beta-galacturonate AqGalA [Aquimarina sp.],7VQM_B Chain B, GH2 beta-galacturonate AqGalA [Aquimarina sp.],7VQM_C Chain C, GH2 beta-galacturonate AqGalA [Aquimarina sp.],7VQM_D Chain D, GH2 beta-galacturonate AqGalA [Aquimarina sp.]
6JZ1_A	1.08e-07	6	383	19	418	Apostructure of b-glucuronidase from Ruminococcus gnavus at 1.7 Angstrom resolution [[Ruminococcus] gnavus],6JZ1_B Apo structure of b-glucuronidase from Ruminococcus gnavus at 1.7 Angstrom resolution [[Ruminococcus] gnavus],6JZ5_A b-glucuronidase from Ruminococcus gnavus in complex with D-glucuronic acid [[Ruminococcus] gnavus],6JZ5_B b-glucuronidase from Ruminococcus gnavus in complex with D-glucuronic acid [[Ruminococcus] gnavus],6JZ6_A b-glucuronidase from Ruminococcus gnavus in complex with C6-substituted uronic isofagomine [[Ruminococcus] gnavus],6JZ6_B b-glucuronidase from Ruminococcus gnavus in complex with C6-substituted uronic isofagomine [[Ruminococcus] gnavus],6JZ7_A b-glucuronidase from Ruminococcus gnavus in complex with N1-substituted uronic isofagomine [[Ruminococcus] gnavus],6JZ7_B b-glucuronidase from Ruminococcus gnavus in complex with N1-substituted uronic isofagomine [[Ruminococcus] gnavus],6JZ8_A b-glucuronidase from Ruminococcus gnavus in complex with D-glucaro 1,5-lactone [[Ruminococcus] gnavus],6JZ8_B b-glucuronidase from Ruminococcus gnavus in complex with D-glucaro 1,5-lactone [[Ruminococcus] gnavus]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q59140	1.27e-06	52	383	108	434	Beta-galactosidase OS=Arthrobacter sp. (strain B7) OX=86041 GN=lacZ PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000042	0.000014	0.000001	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000004612_01308.