CAZyme Information: MGYG000004510_00143

Basic Information

• Species: Prevotella sp002481295
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Prevotella; Prevotella sp002481295
• CAZyme ID: MGYG000004510_00143
• CAZy Family: GH115
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
823	MGYG000004510_2|CGC2	93784.63	7.1162

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000004510	3097673	MAG	Israel	Asia

• Gene Location: Start: 36822; End: 39293 Strand: +

Full Sequence      

MNKILLFLFSLFPLLASANGFYIAKPGQQPATIVVDTTDWTGVRLAARDLSADIGRVCGK
AAPVLVVSSANQPGHGRIIAGTLGKSKMISNIVKAHKIDVRKLRGQWESYLIDVVDGNLV
VVGSDKRGTIYGIYELSREMGVSPWYWWADVPVKHQDHIIYSNGRQYQPSPRVKYRGIFL
NDEAPCLTTWVKNTYGTNYGDHRFYDHVFELLLRLKANFMWPAMWGWAFYADDALNSKTA
DDRGIIIGTSHHEPMCRSQKEWHGHTDDPNVEPQDRASREAAGGQWNYATNQKALDNFWA
GGVRRNKNTEDIVTIGMRGDGDMAMSEDTNIQLMEKIIRNQRRIIEKERGKKASEVPQVW
ALYKEVMDYYDAGLRVPDDVILLLCDDNWGDVRRVPTPKERNRKGGWGLYYHVDYVGAPR
NSKWINVTPIQNMWEQLTLAAENGIDRLWILNVGDLKPMEYPIQLFIDMAWTPTAYTTEN
LLDHTRRFCAAAFGEEQAAEAARILNLQCKFAGRCTAEMLDAKTYSLKDGEWEKAVSDYA
ALERDALRQYTALPESCRDAYQELILFPVQAMANLYDMYYAQAMNHQLYEQGNPDANTWA
ERCRHDFRRDSLLCAAYNHNMAGGKWNGMMIQKHIGYTTWNDNFPHDMLPKLYQVKPRTD
SWIIDAKGDKVVLEAEHYFSKRDGEGARWIDIPFMGPSLGAMTLRPTTASVNGAQLEYRF
RGMQPTDSVTITVTTKCTLDFLNQGGLRYRVSLDGKGETVNFNANLNEKPENIYSIYYPT
VARRIVEKQVTLPLQQLSDGIHRLVFEPLDPGVVLEKITIKTK

Enzyme Prediction     

EC	3.2.1.131

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH115	27	818	3.4e-269	0.9870875179340028

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam15979	Glyco_hydro_115	0.0	170	519	2	334	Glycosyl hydrolase family 115. Glyco_hydro_115 is a family of glycoside hydrolases likely to have the activity of xylan a-1,2-glucuronidase, EC:3.2.1.131, or a-(4-O-methyl)-glucuronidase EC:3.2.1.-.
pfam17829	GH115_C	1.38e-26	671	820	9	158	Gylcosyl hydrolase family 115 C-terminal domain. This domain is found at the C-terminus of glycosyl hydrolase family 115 proteins. This domain has a beta-sandwich fold.
pfam03648	Glyco_hydro_67N	2.21e-04	24	136	13	120	Glycosyl hydrolase family 67 N-terminus. Alpha-glucuronidases, components of an ensemble of enzymes central to the recycling of photosynthetic biomass, remove the alpha-1,2 linked 4-O-methyl glucuronic acid from xylans. This family represents the N-terminal region of alpha-glucuronidase. The N-terminal domain forms a two-layer sandwich, each layer being formed by a beta sheet of five strands. A further two helices form part of the interface with the central, catalytic, module (pfam07488).

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CCG34758.1	0.0	32	820	10	783
BCS85271.1	0.0	33	820	43	813
QNL40611.1	0.0	16	820	28	823
AGB29053.1	0.0	32	820	46	816
QUR44901.1	0.0	17	820	29	823

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
4C90_A	0.0	17	820	40	834	Evidencethat GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C90_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_A Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus]
7PUG_A	1.06e-315	30	820	25	819	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]
7PXQ_A	7.75e-313	30	820	24	818	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]
4ZMH_A	5.76e-182	18	655	10	633	Crystalstructure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40],4ZMH_B Crystal structure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40]
6NPS_A	4.98e-105	41	643	30	648	Crystalstructure of GH115 enzyme AxyAgu115A from Amphibacillus xylanus [Amphibacillus xylanus NBRC 15112],6NPS_B Crystal structure of GH115 enzyme AxyAgu115A from Amphibacillus xylanus [Amphibacillus xylanus NBRC 15112]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000432	0.998806	0.000231	0.000170	0.000172	0.000162

TMHMM  Annotations     

There is no transmembrane helices in MGYG000004510_00143.