CAZyme Information: MGYG000004248_00746

Basic Information

• Species: CAG-170 sp000436735
• Lineage: Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Oscillospiraceae; CAG-170; CAG-170 sp000436735
• CAZyme ID: MGYG000004248_00746
• CAZy Family: GH141
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1814	MGYG000004248_5|CGC1	198324.65	4.2742

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000004248	2100411	MAG	United Kingdom	Europe

• Gene Location: Start: 58592; End: 64036 Strand: +

Full Sequence      

MKKAISLFLALVMLVSVFAGLGITAYAADAQALWVDPVNGSDSAAGTQAAPFQTIEKAKA
AAAALSAGGDVTVWLHGGTYRVSNAITFTSADSGKNGHVITYKAVSGEVPVISGGTPITG
WTIYDAQKNIYVADVPAAAVNSRQFYVDAEHQTRAMTEQSPTDWTLFGTKGYMSPAVTTQ
EANEYLVLDLGKVRSVNYLTAYSSIQADKNGRAAGFPQDFTVETSEDGTAWTVQCEQTGY
ESPVVATAATFNFAPAQARYIKLNATKLGTASRTNPGRYMLAISELETGLKTGSNTDLSE
VVVDYDTNLMTAVEVLGHNENHDWNWLNQTGYGSANLFDNNPDTVVTTGGYYRQQIEVEG
VYPWLSTNISQNGQNAEIAAIRIAVDAINQPVDFTIEISQSNDPGNTDWTIVHSETAFDW
SQSRSAVFIFSPCEAKKVRLHATKIANGEETPGTESDDGKEYALRVAEFAAFAPKSGSSE
PAEIDYTTNLLHPGCVEGIFHNNPNKESYNYDEVGTFPLDALVDGNSSAYSFITSKPYQP
EWLLGNGGSLSPWVEVRLSDNGSAVQLGAVRVAVRPRVVPNDFEIQTSVDGVTWKTVVNE
DNYDWSEEKTAAMFTFQPLQAARLRFVAHNLEKLVEDESYYFQLSELEAYGVAQTISVDT
SNDLLKPGCVSPIYQINGGALQDYTNYTYPLNNLVDDDVQTFISSDSLLRPWLAANGGEL
APWVDVSVTDDGTAVTVGGVQISIQETYNKPVDFSILASEDGQNWTTCRQLKEYDWGETT
SRLFTFAPVSASKLRIQVRDLDGQQEGLPLYFRLTELEAYAPTDFIDIGRVIYVQVSSSE
TCTPSGIAALHDNSDKTYAAEHAINGMYYDNLEHLGYAVPESFGLKNFKNTADIEINILR
WWQHRIFRNSGVSADGTEIYLDTDWLTSLQSTAYSDRITWIENAYEFIDQPGEWYLNRSE
SKLYYKPDGSMDGKSATLPVTEQLLVFEGTENITFDGVKFEDTSWLTPNEIGYNDAQSGT
YAQHNGVWGDVPGAIETHAAKNITITNSELCNLGGGGIRIGNGSSDCAITNSAIHDISSS
GIFIGNNTGHNHGYCDPGTDVTGVVVRNNYITRTGLDIFGSSAICALYTSDTVIDHNEVC
YTTYTGISLGWGWDWKNAPCSGNNTVSNNYIHDTGKTIHDGGSFYSLGLQEGTKVFGNYL
HHHSDGLYDKDGGLYTDEGSTGMELYNNVVGDGVYWWQKIWTTNIKDCYWHDNFYSVNRS
WDSGVNIRQENNTYVEGGDFSQYPAAQAIINNAGLTDPSVKDGVRMGIAEKHNVTLMQYP
DGEAYYFEKPAGLLTFTIPSQIGNTQYDKLAHTANILMPESTDRTSLAGNFTMAPGFTCD
KTSGSLQNFTSPVVYTFTDGTDTIAWTVTVTCDVTADGPLVGTETTLDAAIAARSDWTQE
PAEAENGGALFTPAKSFSAYIGDRIANDAILEFDVQSVLDGNDWTGYALRMQDPYSTLGT
MYHIVFKQDAIELQKWVNGNRTMLIGTIEGYDPVYGDVENKFYTSDIRHSIKTGAIDVPT
GVRLFLYIDGNKVFDVIDADSPITGSGFFGMYPMTHDMTLLPFSNIDTSPKPDPDPDPEP
KPILPILPSGGQSAWKNPYQDVTDSSSYYEAVRYVTEKGLMNGTSASTFSPDAAMTRAMM
VTILWRMEKEPAALKSNFTDLTADWYRTAVDWAAETGVVNGVGNGKFAPNATLSLEQLIT
ILYRYAENKGYNVSKSASLDSFTDGSAVSAYAKPAMQWAVGMNFLSGNTLTPCAPASRAQ
IAQVLMLFCKAYIK

Enzyme Prediction     

No EC number prediction in MGYG000004248_00746.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH141	880	1230	2.1e-85	0.7172675521821632

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam13229	Beta_helix	1.77e-09	1033	1229	1	157	Right handed beta helix region. This region contains a parallel beta helix region that shares some similarity with Pectate lyases.
NF033190	inl_like_NEAT_1	3.28e-08	1639	1805	582	748	NEAT domain-containing leucine-rich repeat protein. Members of this family have an N-terminal NEAT (near transporter) domain often associated with iron transport, followed by a leucine-rich repeat region with significant sequence similarity to the internalins of Listeria monocytogenes. However, since Bacillus cereus (from which this protein was described, in PMID:16978259) is not considered an intracellular pathogen, and the function may be iron transport rather than internalization, applying the name "internalin" to this family probably would be misleading.
pfam00395	SLH	3.77e-07	1639	1678	1	40	S-layer homology domain.
pfam00754	F5_F8_type_C	2.21e-06	182	270	33	117	F5/8 type C domain. This domain is also known as the discoidin (DS) domain family.
NF033190	inl_like_NEAT_1	3.59e-06	1636	1743	640	749	NEAT domain-containing leucine-rich repeat protein. Members of this family have an N-terminal NEAT (near transporter) domain often associated with iron transport, followed by a leucine-rich repeat region with significant sequence similarity to the internalins of Listeria monocytogenes. However, since Bacillus cereus (from which this protein was described, in PMID:16978259) is not considered an intracellular pathogen, and the function may be iron transport rather than internalization, applying the name "internalin" to this family probably would be misleading.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QJD87486.1	1.71e-230	34	1807	38	1824
BBI36522.1	7.38e-47	876	1295	172	596
QGQ95096.1	3.13e-41	874	1255	64	511
BAV33387.1	3.69e-41	876	1236	161	523
QJD86426.1	2.84e-40	876	1297	178	615

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5MQP_A	4.99e-26	917	1228	232	580	Glycosidehydrolase BT_1002 [Bacteroides thetaiotaomicron],5MQP_B Glycoside hydrolase BT_1002 [Bacteroides thetaiotaomicron],5MQP_C Glycoside hydrolase BT_1002 [Bacteroides thetaiotaomicron],5MQP_D Glycoside hydrolase BT_1002 [Bacteroides thetaiotaomicron],5MQP_E Glycoside hydrolase BT_1002 [Bacteroides thetaiotaomicron],5MQP_F Glycoside hydrolase BT_1002 [Bacteroides thetaiotaomicron],5MQP_G Glycoside hydrolase BT_1002 [Bacteroides thetaiotaomicron],5MQP_H Glycoside hydrolase BT_1002 [Bacteroides thetaiotaomicron]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P19424	6.53e-14	1638	1805	40	210	Endoglucanase OS=Bacillus sp. (strain KSM-635) OX=1415 PE=1 SV=1
P38537	9.41e-10	1650	1804	45	201	Surface-layer 125 kDa protein OS=Lysinibacillus sphaericus OX=1421 PE=3 SV=1
C6CRV0	1.94e-08	1650	1805	1294	1455	Endo-1,4-beta-xylanase A OS=Paenibacillus sp. (strain JDR-2) OX=324057 GN=xynA1 PE=1 SV=1
P22258	4.06e-07	1638	1744	30	143	Cell surface protein OS=Thermoanaerobacter kivui OX=2325 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000240	0.999118	0.000152	0.000188	0.000148	0.000141

TMHMM  Annotations     

start	end
5	27