You are browsing environment: HUMAN GUT
CAZyme Information: MGYG000004191_00597
You are here: Home > Sequence: MGYG000004191_00597
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | CAG-269 sp001916005 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; TANB77; CAG-508; CAG-269; CAG-269 sp001916005 | |||||||||||
| CAZyme ID | MGYG000004191_00597 | |||||||||||
| CAZy Family | GT25 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 31016; End: 33124 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT25 | 42 | 243 | 7.6e-36 | 0.9779005524861878 |
| GH16 | 498 | 682 | 1.1e-33 | 0.8543689320388349 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam00722 | Glyco_hydro_16 | 2.35e-30 | 500 | 662 | 1 | 151 | Glycosyl hydrolases family 16. |
| cd02175 | GH16_lichenase | 3.26e-29 | 501 | 667 | 30 | 189 | lichenase, member of glycosyl hydrolase family 16. Lichenase, also known as 1,3-1,4-beta-glucanase, is a member of glycosyl hydrolase family 16, that specifically cleaves 1,4-beta-D-glucosidic bonds in mixed-linked beta glucans that also contain 1,3-beta-D-glucosidic linkages. Natural substrates of beta-glucanase are beta-glucans from grain endosperm cell walls or lichenan from the Islandic moss, Cetraria islandica. This protein is found not only in bacteria but also in anaerobic fungi. This domain includes two seven-stranded antiparallel beta-sheets that are adjacent to one another forming a compact, jellyroll beta-sandwich structure. |
| cd06532 | Glyco_transf_25 | 8.61e-29 | 43 | 245 | 1 | 128 | Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of Neisseria gonorrhoeae and Lic2A of Haemophilus influenzae. M. catarrhalis Lgt2 catalyzes the addition of galactose (Gal) to the growing chain of LOS on the cell surface. N. gonorrhoeae LgtB and LgtE link Gal-beta(1,4) to GlcNAc (N-acetylglucosamine) and Glc (glucose), respectively. The genes encoding LgtB and LgtE are two genes of a five gene locus involved in the synthesis of gonococcal LOS. LgtE is believed to perform the first step in LOS biosynthesis. |
| pfam01755 | Glyco_transf_25 | 2.11e-25 | 44 | 242 | 4 | 197 | Glycosyltransferase family 25 (LPS biosynthesis protein). Members of this family belong to Glycosyltransferase family 25 This is a family of glycosyltransferases involved in lipopolysaccharide (LPS) biosynthesis. These enzymes catalyze the transfer of various sugars onto the growing LPS chain during its biosynthesis. |
| cd00413 | Glyco_hydrolase_16 | 5.94e-25 | 474 | 688 | 2 | 209 | glycosyl hydrolase family 16. The O-Glycosyl hydrolases are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A glycosyl hydrolase classification system based on sequence similarity has led to the definition of more than 95 different families inlcuding glycosyl hydrolase family 16. Family 16 includes lichenase, xyloglucan endotransglycosylase (XET), beta-agarase, kappa-carrageenase, endo-beta-1,3-glucanase, endo-beta-1,3-1,4-glucanase, and endo-beta-galactosidase, all of which have a conserved jelly roll fold with a deep active site channel harboring the catalytic residues. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AKM79208.1 | 1.19e-208 | 12 | 686 | 12 | 702 |
| CCH88516.1 | 6.24e-169 | 12 | 688 | 12 | 701 |
| BBP25550.1 | 6.25e-155 | 8 | 686 | 8 | 712 |
| BBY52679.1 | 5.35e-153 | 39 | 688 | 40 | 703 |
| QIT29136.1 | 4.80e-151 | 8 | 686 | 8 | 712 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 2R49_A | 3.02e-16 | 524 | 691 | 3 | 169 | ChainA, Beta-glucanase [Fibrobacter succinogenes] |
| 3H0O_A | 4.01e-16 | 524 | 691 | 2 | 168 | ChainA, Beta-glucanase [Fibrobacter succinogenes] |
| 3AXD_A | 1.17e-15 | 523 | 691 | 4 | 171 | Thetruncated Fibrobacter succinogenes 1,3-1,4-beta-D-glucanase V18Y/W203Y in apo-form [Fibrobacter succinogenes subsp. succinogenes S85],3AXD_B The truncated Fibrobacter succinogenes 1,3-1,4-beta-D-glucanase V18Y/W203Y in apo-form [Fibrobacter succinogenes subsp. succinogenes S85],3AXE_A The truncated Fibrobacter succinogenes 1,3-1,4-beta-D-glucanase V18Y/W203Y in complex with cellotetraose (cellobiose density was observed) [Fibrobacter succinogenes subsp. succinogenes S85] |
| 3HR9_A | 2.51e-15 | 524 | 691 | 3 | 169 | ChainA, Beta-glucanase [Fibrobacter succinogenes] |
| 1ZM1_A | 3.39e-15 | 524 | 691 | 2 | 168 | Crystalstructures of complex F. succinogenes 1,3-1,4-beta-D-glucanase and beta-1,3-1,4-cellotriose [Fibrobacter succinogenes],1ZM1_B Crystal structures of complex F. succinogenes 1,3-1,4-beta-D-glucanase and beta-1,3-1,4-cellotriose [Fibrobacter succinogenes] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P37073 | 5.42e-18 | 498 | 682 | 67 | 243 | Beta-glucanase OS=Brevibacillus brevis OX=1393 GN=bglBB PE=1 SV=1 |
| P17989 | 1.01e-14 | 524 | 691 | 28 | 194 | Beta-glucanase OS=Fibrobacter succinogenes (strain ATCC 19169 / S85) OX=59374 GN=Fisuc_2961 PE=1 SV=1 |
| A3DBX3 | 2.17e-13 | 498 | 661 | 62 | 215 | Beta-glucanase OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=licB PE=1 SV=1 |
| Q84C00 | 1.25e-12 | 498 | 667 | 62 | 221 | Beta-glucanase OS=Acetivibrio thermocellus OX=1515 GN=licB PE=1 SV=1 |
| Q8IPK4 | 8.96e-12 | 35 | 251 | 326 | 521 | Glycosyltransferase 25 family member OS=Drosophila melanogaster OX=7227 GN=CG31915 PE=2 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000054 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |