CAZyme Information: MGYG000004129_00245

Basic Information

• Species: Acutalibacter sp000435395
• Lineage: Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Acutalibacteraceae; Acutalibacter; Acutalibacter sp000435395
• CAZyme ID: MGYG000004129_00245
• CAZy Family: GH2
• CAZyme Description: Beta-galactosidase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
810	MGYG000004129_3|CGC3	89853.03	5.0177

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000004129	2343469	MAG	United Kingdom	Europe

• Gene Location: Start: 82923; End: 85355 Strand: +

Full Sequence      

MAREQILWNKGWKFRHGDFPAAAAPAFDDSAWADICLPHSFGIPYFMEGQFYVGYGCYRK
SLFLPQAWLGKRVALEFQAAFQAAEVYVNGQLAGSHKGGYTPFVVDMTELLRPGENLVFV
RVNNLWDSRQAPRAGEHVFNGGIYRDVSLLVTDPVRVAWEGVWVTTPQASRERALVEVQT
EVENLTAQNRPFRLSSVVKYQGEAVAQAESRGEAAPGKKESFTQQLEVLAPHLWSPESPE
LYTLETTLSVEGQEPERQETTFGVRWFAFTAKEGFFLNGEPYKIHGANVHQDHAGWSDAV
THTGIARDVKLIKDCGMNFIRGSHYPHHTVFAQECDRQGVLFWSENCFWGTGGPKQEGYW
TASAYPIRQEDEAEFEESCLRSLEEMIRANRNHPSIVVWSMCNEPFFTDAGTSEKMKALL
QKLVAASHRLDPTRPAAIGGAQRGGIDVLGDVAGYNGDGAAIFHDPGFPNFVSEYGSSVS
DRPGNFAPNYTDGVEQPHPWRSGISLWCGFHHGSILFDMGHMGMIDYYRLPLDTWHWYRE
NLLGIPRPEHAVEGQAARLSLTADRLELTDDGTQDVQLVVSLLGEDGRRVLSPQQVRLEV
VSGGAVFPTGKVYEMSGEKGSLLGGMGAIELRALYPGETVIRAQAEGVPPVELQLLVTGD
SPWDGRELVPLPAPPSVMGPPPRQALDEIGLYRPVFASGEDSQCPAKNVTDGQWETCWKP
ASPEAGQWVMVDLEGTKDVEGIHVVFRGMVQHAVEVALSHTREDFRTIYNSGERPAVTDV
SLDNLGQQARFIRVRFPGETTPICKIEVFA

Enzyme Prediction     

No EC number prediction in MGYG000004129_00245.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH2	3	592	8.7e-105	0.6688829787234043

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG3250	LacZ	1.45e-55	1	405	8	407	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
PRK10150	PRK10150	2.65e-54	52	435	63	444	beta-D-glucuronidase; Provisional
PRK10340	ebgA	3.77e-38	56	434	111	470	cryptic beta-D-galactosidase subunit alpha; Reviewed
pfam02836	Glyco_hydro_2_C	1.42e-24	272	538	5	261	Glycosyl hydrolases family 2, TIM barrel domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.
PRK09525	lacZ	3.40e-23	56	435	122	484	beta-galactosidase.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ASA23481.1	0.0	3	809	7	811
ADI13036.1	3.25e-271	1	808	1	806
QCQ41481.1	3.33e-237	3	808	33	858
QUU02609.1	4.72e-237	3	808	33	858
ANQ60352.1	6.67e-237	3	808	33	858

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5UJ6_A	1.80e-71	3	539	25	602	CrystalStructure of Bacteroides Uniformis beta-glucuronidase [Bacteroides uniformis str. 3978 T3 ii],5UJ6_B Crystal Structure of Bacteroides Uniformis beta-glucuronidase [Bacteroides uniformis str. 3978 T3 ii],6NZG_A Bacteroides uniformis beta-glucuronidase 2 covalently bound to cyclophellitol-6-carboxylate aziridine [Bacteroides uniformis],6NZG_B Bacteroides uniformis beta-glucuronidase 2 covalently bound to cyclophellitol-6-carboxylate aziridine [Bacteroides uniformis]
6D50_A	2.00e-71	3	539	33	610	Bacteroidesuniforms beta-glucuronidase 2 bound to D-glucaro-1,5-lactone [Bacteroides uniformis str. 3978 T3 ii],6D50_B Bacteroides uniforms beta-glucuronidase 2 bound to D-glucaro-1,5-lactone [Bacteroides uniformis str. 3978 T3 ii]
6D8G_A	3.77e-71	3	539	33	610	D341AD367A calcium binding mutant of Bacteroides uniformis beta-glucuronidase 2 [Bacteroides uniformis str. 3978 T3 ii],6D8G_B D341A D367A calcium binding mutant of Bacteroides uniformis beta-glucuronidase 2 [Bacteroides uniformis str. 3978 T3 ii]
5T98_A	5.82e-60	6	439	28	450	Crystalstructure of BuGH2Awt [Bacteroides uniformis],5T98_B Crystal structure of BuGH2Awt [Bacteroides uniformis],5T99_A Crystal structure of BuGH2Awt in complex with Galactoisofagomine [Bacteroides uniformis],5T99_B Crystal structure of BuGH2Awt in complex with Galactoisofagomine [Bacteroides uniformis]
4YPJ_A	3.80e-58	5	501	9	490	ChainA, Beta galactosidase [Niallia circulans],4YPJ_B Chain B, Beta galactosidase [Niallia circulans]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
A7LXS9	2.56e-54	3	475	42	535	Beta-galactosidase BoGH2A OS=Bacteroides ovatus (strain ATCC 8483 / DSM 1896 / JCM 5824 / BCRC 10623 / CCUG 4943 / NCTC 11153) OX=411476 GN=BACOVA_02645 PE=1 SV=1
T2KPJ7	3.81e-51	26	438	73	468	Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_21970 PE=2 SV=1
P77989	2.01e-43	1	539	1	533	Beta-galactosidase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) OX=340099 GN=lacZ PE=3 SV=2
T2KM09	2.65e-40	3	450	46	468	Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_22050 PE=2 SV=2
T2KN75	1.12e-35	3	455	26	477	Beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_22060 PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000057	0.000001	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000004129_00245.