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CAZyme Information: MGYG000004052_01016
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | SFMI01 sp004556155 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia_A; Christensenellales; CAG-74; SFMI01; SFMI01 sp004556155 | |||||||||||
| CAZyme ID | MGYG000004052_01016 | |||||||||||
| CAZy Family | GT39 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 71126; End: 73990 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT39 | 496 | 723 | 7.8e-50 | 0.9192825112107623 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| COG1928 | PMT1 | 1.70e-19 | 500 | 950 | 50 | 691 | Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]. |
| pfam02366 | PMT | 1.66e-17 | 493 | 720 | 16 | 239 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families. |
| pfam16192 | PMT_4TMC | 1.97e-15 | 741 | 950 | 10 | 198 | C-terminal four TMM region of protein-O-mannosyltransferase. PMT_4TMC is the C-terminal four membrane-pass region of protein-O-mannosyltransferases and similar enzymes. |
| COG1807 | ArnT | 7.02e-15 | 494 | 675 | 51 | 207 | 4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family [Cell wall/membrane/envelope biogenesis]. |
| pfam13231 | PMT_2 | 5.90e-14 | 522 | 667 | 1 | 137 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QUC68008.1 | 1.51e-141 | 313 | 954 | 768 | 1422 |
| QTE71236.1 | 4.36e-139 | 324 | 954 | 770 | 1407 |
| QTE75201.1 | 5.58e-139 | 324 | 954 | 785 | 1422 |
| QTE68569.1 | 4.66e-126 | 331 | 944 | 751 | 1392 |
| QUA53848.1 | 6.99e-123 | 313 | 954 | 707 | 1372 |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P9WN04 | 6.00e-19 | 500 | 951 | 73 | 520 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pmt PE=3 SV=2 |
| P9WN05 | 6.00e-19 | 500 | 951 | 73 | 520 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=pmt PE=1 SV=2 |
| L8F4Z2 | 5.34e-17 | 490 | 942 | 57 | 506 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycolicibacterium smegmatis (strain MKD8) OX=1214915 GN=pmt PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.993581 | 0.005795 | 0.000562 | 0.000020 | 0.000013 | 0.000051 |
TMHMM Annotations download full data without filtering help
| start | end |
|---|---|
| 7 | 24 |
| 211 | 228 |
| 235 | 257 |
| 267 | 289 |
| 333 | 355 |
| 545 | 567 |
| 598 | 617 |
| 642 | 664 |
| 696 | 718 |
| 788 | 810 |
| 840 | 862 |
| 867 | 889 |
| 910 | 932 |