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CAZyme Information: MGYG000003955_00637
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Acutalibacteraceae; UMGS1976; | |||||||||||
| CAZyme ID | MGYG000003955_00637 | |||||||||||
| CAZy Family | GH27 | |||||||||||
| CAZyme Description | Alpha-galactosidase A | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 120342; End: 121481 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH27 | 102 | 350 | 2e-64 | 0.9737991266375546 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd14792 | GH27 | 2.64e-139 | 6 | 279 | 1 | 271 | glycosyl hydrolase family 27 (GH27). GH27 enzymes occur in eukaryotes, prokaryotes, and archaea with a wide range of hydrolytic activities, including alpha-glucosidase (glucoamylase and sucrase-isomaltase), alpha-N-acetylgalactosaminidase, and 3-alpha-isomalto-dextranase. All GH27 enzymes cleave a terminal carbohydrate moiety from a substrate that varies considerably in size, depending on the enzyme, and may be either a starch or a glycoprotein. GH27 members are retaining enzymes that cleave their substrates via an acid/base-catalyzed, double-displacement mechanism involving a covalent glycosyl-enzyme intermediate. Two aspartic acid residues have been identified as the catalytic nucleophile and the acid/base, respectively. |
| PLN02808 | PLN02808 | 1.15e-97 | 6 | 279 | 32 | 295 | alpha-galactosidase |
| PLN02229 | PLN02229 | 8.13e-94 | 6 | 279 | 63 | 325 | alpha-galactosidase |
| PLN02692 | PLN02692 | 3.75e-89 | 6 | 337 | 56 | 372 | alpha-galactosidase |
| pfam16499 | Melibiase_2 | 2.92e-84 | 6 | 279 | 2 | 284 | Alpha galactosidase A. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| VCV24057.1 | 1.88e-148 | 1 | 350 | 1 | 347 |
| AEE96273.1 | 5.36e-148 | 1 | 378 | 1 | 376 |
| QAA34453.1 | 2.87e-147 | 1 | 378 | 1 | 374 |
| QTE68632.1 | 9.14e-139 | 1 | 378 | 1 | 393 |
| QUC67774.1 | 1.16e-137 | 1 | 366 | 4 | 380 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 1UAS_A | 7.53e-80 | 6 | 376 | 9 | 361 | ChainA, alpha-galactosidase [Oryza sativa] |
| 4OGZ_A | 9.42e-78 | 2 | 317 | 96 | 419 | Crystalstructure of a putative alpha-galactosidase/melibiase (BF4189) from Bacteroides fragilis NCTC 9343 at 2.00 A resolution [Bacteroides fragilis NCTC 9343],4OGZ_B Crystal structure of a putative alpha-galactosidase/melibiase (BF4189) from Bacteroides fragilis NCTC 9343 at 2.00 A resolution [Bacteroides fragilis NCTC 9343] |
| 6F4C_B | 1.91e-74 | 6 | 333 | 9 | 321 | Nicotianabenthamiana alpha-galactosidase [Nicotiana benthamiana] |
| 4NZJ_A | 5.92e-73 | 2 | 317 | 96 | 419 | Crystalstructure of a putative alpha-galactosidase (BF1418) from Bacteroides fragilis NCTC 9343 at 1.57 A resolution [Bacteroides fragilis NCTC 9343] |
| 3A5V_A | 2.19e-72 | 6 | 312 | 9 | 334 | Crystalstructure of alpha-galactosidase I from Mortierella vinacea [Umbelopsis vinacea] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P14749 | 3.93e-83 | 6 | 279 | 56 | 319 | Alpha-galactosidase OS=Cyamopsis tetragonoloba OX=3832 PE=1 SV=1 |
| Q8RX86 | 4.01e-82 | 6 | 279 | 40 | 303 | Alpha-galactosidase 2 OS=Arabidopsis thaliana OX=3702 GN=AGAL2 PE=1 SV=1 |
| Q8VXZ7 | 1.83e-81 | 2 | 279 | 69 | 335 | Alpha-galactosidase 3 OS=Arabidopsis thaliana OX=3702 GN=AGAL3 PE=1 SV=1 |
| Q9URZ0 | 1.10e-79 | 5 | 332 | 32 | 375 | Alpha-galactosidase mel1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=mel1 PE=3 SV=1 |
| Q9FXT4 | 2.03e-78 | 6 | 376 | 64 | 416 | Alpha-galactosidase OS=Oryza sativa subsp. japonica OX=39947 GN=Os10g0493600 PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.967827 | 0.031043 | 0.000641 | 0.000139 | 0.000073 | 0.000283 |