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CAZyme Information: MGYG000003882_01100
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Klebsiella; | |||||||||||
| CAZyme ID | MGYG000003882_01100 | |||||||||||
| CAZy Family | GT9 | |||||||||||
| CAZyme Description | Lipopolysaccharide core heptosyltransferase RfaQ | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 1127; End: 2203 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT9 | 86 | 321 | 5.1e-62 | 0.9066666666666666 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| TIGR02201 | heptsyl_trn_III | 0.0 | 15 | 358 | 1 | 344 | lipopolysaccharide heptosyltransferase III, putative. This family consists of examples of the putative ADP-heptose:LPS heptosyltransferase III, an enzyme of LPS inner core region biosynthesis. LPS, composed of lipid A, a core region, and O antigen, is found in the outer membrane of Gram-negative bacteria. This enzyme may be less widely distributed than heptosyltransferases I and II. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides] |
| PRK10422 | PRK10422 | 6.40e-122 | 13 | 357 | 5 | 343 | lipopolysaccharide core biosynthesis protein; Provisional |
| COG0859 | RfaF | 8.11e-83 | 15 | 358 | 3 | 331 | ADP-heptose:LPS heptosyltransferase [Cell wall/membrane/envelope biogenesis]. |
| cd03789 | GT9_LPS_heptosyltransferase | 1.73e-81 | 15 | 355 | 1 | 277 | lipopolysaccharide heptosyltransferase and similar proteins. Lipopolysaccharide heptosyltransferase (2.4.99.B6) is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from ADP-heptose to 3-deoxy-D-manno-octulosonic acid (KDO), a part of the inner core component of LPS. This family also contains lipopolysaccharide 1,2-N-acetylglucosaminetransferase EC 2.4.1.56 and belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. |
| pfam01075 | Glyco_transf_9 | 2.28e-57 | 87 | 341 | 2 | 247 | Glycosyltransferase family 9 (heptosyltransferase). Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QVJ11243.1 | 1.23e-255 | 1 | 358 | 1 | 358 |
| QII32815.1 | 5.02e-255 | 1 | 358 | 1 | 358 |
| QGT19260.1 | 4.13e-254 | 1 | 358 | 1 | 358 |
| AEG96192.1 | 4.13e-254 | 1 | 358 | 1 | 358 |
| QEU20903.1 | 4.13e-254 | 1 | 358 | 1 | 358 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 1PSW_A | 7.40e-16 | 15 | 318 | 2 | 305 | Structureof E. coli ADP-heptose lps heptosyltransferase II [Escherichia coli] |
| 3TOV_A | 2.73e-14 | 15 | 357 | 10 | 345 | Thecrystal structure of the glycosyl transferase family 9 from Veillonella parvula DSM 2008 [Veillonella parvula DSM 2008],3TOV_B The crystal structure of the glycosyl transferase family 9 from Veillonella parvula DSM 2008 [Veillonella parvula DSM 2008] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q9R9D5 | 4.46e-90 | 21 | 357 | 1 | 331 | Lipopolysaccharide core heptosyltransferase RfaQ OS=Escherichia coli OX=562 GN=rfaQ PE=1 SV=1 |
| P25742 | 3.33e-85 | 21 | 357 | 1 | 331 | Lipopolysaccharide core heptosyltransferase RfaQ OS=Escherichia coli (strain K12) OX=83333 GN=rfaQ PE=3 SV=2 |
| P37692 | 1.44e-18 | 15 | 318 | 2 | 305 | ADP-heptose--LPS heptosyltransferase 2 OS=Escherichia coli (strain K12) OX=83333 GN=rfaF PE=1 SV=1 |
| P37421 | 6.72e-18 | 15 | 318 | 2 | 305 | ADP-heptose--LPS heptosyltransferase 2 OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=rfaF PE=3 SV=1 |
| Q57336 | 8.12e-14 | 13 | 318 | 8 | 299 | Lipopolysaccharide core heptosyltransferase OpsX OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=opsX PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000050 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |