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CAZyme Information: MGYG000003742_01444

You are here: Home > Sequence: MGYG000003742_01444

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Prevotella buccalis
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Prevotella; Prevotella buccalis
CAZyme ID MGYG000003742_01444
CAZy Family GH33
CAZyme Description Sialidase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
373 MGYG000003742_38|CGC1 41466.6 6.5775
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003742 2540681 MAG Canada North America
Gene Location Start: 15300;  End: 16421  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000003742_01444.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH33 42 355 1.5e-85 0.9152046783625731

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd15482 Sialidase_non-viral 1.65e-100 43 368 9 339
Non-viral sialidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates, they play vital roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold with the non-viral sialidases containing 2-5 Asp-box motifs (most commonly Ser/Thr-X-Asp-[X]-Gly-X-Thr- Trp/Phe). This CD includes eubacterial and eukaryotic sialidases.
pfam13088 BNR_2 8.05e-36 59 350 1 280
BNR repeat-like domain. This family of proteins contains BNR-like repeats suggesting these proteins may act as sialidases.
COG4409 NanH 1.61e-11 48 365 275 651
Neuraminidase (sialidase) [Carbohydrate transport and metabolism, Cell wall/membrane/envelope biogenesis].
pfam13859 BNR_3 1.42e-10 50 267 1 211
BNR repeat-like domain. This family of proteins contains BNR-like repeats suggesting these proteins may act as sialidases.
cd00260 Sialidase 4.45e-07 44 343 11 325
sialidases/neuraminidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed beta-propeller fold. This hierarchy includes eubacterial, eukaryotic, and viral sialidases.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QRP58590.1 1.08e-177 1 373 1 369
QQT79528.1 1.08e-177 1 373 1 369
ASM67226.1 1.08e-177 1 373 1 369
QUU09870.1 1.08e-177 1 373 1 369
QIU96716.1 3.59e-176 1 373 1 369

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
4FJ6_A 9.53e-36 43 372 176 520
Crystalstructure of a glycoside hydrolase family 33, candidate sialidase (BDI_2946) from Parabacteroides distasonis ATCC 8503 at 1.90 A resolution [Parabacteroides distasonis ATCC 8503],4FJ6_B Crystal structure of a glycoside hydrolase family 33, candidate sialidase (BDI_2946) from Parabacteroides distasonis ATCC 8503 at 1.90 A resolution [Parabacteroides distasonis ATCC 8503],4FJ6_C Crystal structure of a glycoside hydrolase family 33, candidate sialidase (BDI_2946) from Parabacteroides distasonis ATCC 8503 at 1.90 A resolution [Parabacteroides distasonis ATCC 8503],4FJ6_D Crystal structure of a glycoside hydrolase family 33, candidate sialidase (BDI_2946) from Parabacteroides distasonis ATCC 8503 at 1.90 A resolution [Parabacteroides distasonis ATCC 8503]
1EUR_A 2.30e-34 31 372 7 359
Sialidase[Micromonospora viridifaciens],1EUS_A Sialidase Complexed With 2-Deoxy-2,3-Dehydro-N- Acetylneuraminic Acid [Micromonospora viridifaciens]
6MNJ_A 1.43e-33 48 372 200 537
Hadzamicrobial sialidase Hz136 [Alistipes],6MNJ_B Hadza microbial sialidase Hz136 [Alistipes]
1W8N_A 2.10e-33 31 372 3 355
Contributionof the Active Site Aspartic Acid to Catalysis in the Bacterial Neuraminidase from Micromonospora viridifaciens. [Micromonospora viridifaciens],1W8O_A Contribution of the Active Site Aspartic Acid to Catalysis in the Bacterial Neuraminidase from Micromonospora viridifaciens [Micromonospora viridifaciens]
6MYV_A 2.19e-33 43 372 176 520
Sialidase26co-crystallized with DANA-Gc [bacterium],6MYV_B Sialidase26 co-crystallized with DANA-Gc [bacterium],6MYV_C Sialidase26 co-crystallized with DANA-Gc [bacterium],6MYV_D Sialidase26 co-crystallized with DANA-Gc [bacterium]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P31206 2.13e-33 43 372 198 542
Sialidase OS=Bacteroides fragilis (strain YCH46) OX=295405 GN=nanH PE=3 SV=2
Q02834 2.73e-32 31 372 49 401
Sialidase OS=Micromonospora viridifaciens OX=1881 GN=nedA PE=1 SV=1
O35657 2.41e-30 48 355 71 390
Sialidase-1 OS=Mus musculus OX=10090 GN=Neu1 PE=1 SV=1
Q99PW3 8.72e-30 48 355 71 390
Sialidase-1 OS=Rattus norvegicus OX=10116 GN=Neu1 PE=1 SV=1
A5PF10 1.24e-28 48 355 78 397
Sialidase-1 OS=Sus scrofa OX=9823 GN=NEU1 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as LIPO

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000008 0.007164 0.992863 0.000002 0.000003 0.000003

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000003742_01444.