logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000003546_01425

You are here: Home > Sequence: MGYG000003546_01425

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species UBA1181 sp900769555
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Paludibacteraceae; UBA1181; UBA1181 sp900769555
CAZyme ID MGYG000003546_01425
CAZy Family GH26
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
895 MGYG000003546_106|CGC2 99755.12 4.3669
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003546 3032937 MAG Fiji Oceania
Gene Location Start: 22876;  End: 25563  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000003546_01425.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH26 16 340 5.4e-98 0.9966996699669967
GH5 510 757 2e-86 0.9881422924901185

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam02156 Glyco_hydro_26 2.06e-51 16 340 1 311
Glycosyl hydrolase family 26.
pfam00150 Cellulase 5.06e-27 509 754 1 272
Cellulase (glycosyl hydrolase family 5).
COG4124 ManB2 9.79e-19 171 314 178 322
Beta-mannanase [Carbohydrate transport and metabolism].
cd04086 CBM35_mannanase-like 2.14e-16 364 483 3 119
Carbohydrate Binding Module 35 (CBM35); appended to several carbohydrate binding enzymes, including several glycoside hydrolase (GH) family 26 mannanase domains. This family includes carbohydrate binding module 35 (CBM35) domains that are appended to several carbohydrate binding enzymes, including periplasmic component of ABC-type sugar transport system involved in carbohydrate transport and metabolism, and several glycoside hydrolase (GH) domains, including GH26. These CBM6s are non-catalytic carbohydrate binding domains that facilitate the strong binding of the GH catalytic modules with their dedicated, insoluble substrates. Examples of proteins having CMB35s belonging to this family are mannanase A from Clostridium thermocellum (GH26), Man26B from Paenibacillus sp. BME-14 (GH26), and the multifunctional Cel44C-Man26A from Paenibacillus polymyxa GS01 (which has two GH domains, GH44 and GH26). GH26 mainly includes mannan endo-1,4-beta-mannosidase which hydrolyzes 1,4-beta-D-linkages in mannans, galacto-mannans, glucomannans, and galactoglucomannans, but displays little activity towards other plant cell wall polysaccharides. A few proteins belonging to this family have additional CBM3 domains; these CBM3s are not found in the CBM6-CBM35-CBM36_like superfamily.
pfam16990 CBM_35 8.77e-10 363 483 1 118
Carbohydrate binding module (family 35). This is a mannan-specific carbohydrate binding domain, previously known as the X4 module. Unlike other carbohydrate binding modules, binding to substrate causes a conformational change.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
ADX05709.1 0.0 9 865 31 881
ADL27067.1 7.37e-122 16 362 152 505
ACX74337.1 7.37e-122 16 362 152 505
ACX74340.1 5.98e-121 10 411 150 612
ADL26627.1 1.96e-114 10 353 143 491

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
2WHJ_A 4.21e-82 500 787 2 287
Understandinghow diverse mannanases recognise heterogeneous substrates [Salipaludibacillus agaradhaerens]
3JUG_A 3.65e-81 500 787 24 309
Crystalstructure of endo-beta-1,4-mannanase from the alkaliphilic Bacillus sp. N16-5 [Bacillus sp. N16-5]
1WKY_A 8.62e-80 500 793 9 300
Crystalstructure of alkaline mannanase from Bacillus sp. strain JAMB-602: catalytic domain and its Carbohydrate Binding Module [Bacillus sp. JAMB-602]
2WHL_A 5.48e-79 500 787 1 284
Understandinghow diverse mannanases recognise heterogeneous substrates [Salipaludibacillus agaradhaerens]
3WDQ_A 2.60e-62 11 344 30 355
Crystalstructure of beta-mannanase from a symbiotic protist of the termite Reticulitermes speratus [Symbiotic protist of Reticulitermes speratus],3WDR_A Crystal structure of beta-mannanase from a symbiotic protist of the termite Reticulitermes speratus complexed with gluco-manno-oligosaccharide [Symbiotic protist of Reticulitermes speratus]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
G1K3N4 2.30e-81 500 787 2 287
Mannan endo-1,4-beta-mannosidase OS=Salipaludibacillus agaradhaerens OX=76935 PE=1 SV=1
P51529 1.22e-53 464 785 6 324
Mannan endo-1,4-beta-mannosidase OS=Streptomyces lividans OX=1916 GN=manA PE=1 SV=2
G2Q4H7 3.84e-51 10 344 169 479
Mannan endo-1,4-beta-mannosidase OS=Myceliophthora thermophila (strain ATCC 42464 / BCRC 31852 / DSM 1799) OX=573729 GN=Man26A PE=1 SV=1
B3PF24 1.47e-50 495 785 43 334
Mannan endo-1,4-beta-mannosidase OS=Cellvibrio japonicus (strain Ueda107) OX=498211 GN=man5A PE=1 SV=1
P49425 2.27e-48 13 347 144 463
Mannan endo-1,4-beta-mannosidase OS=Rhodothermus marinus (strain ATCC 43812 / DSM 4252 / R-10) OX=518766 GN=manA PE=1 SV=3

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000046 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000003546_01425.