CAZyme Information: MGYG000003538_00021

Basic Information

• Species: UBA737 sp900769375
• Lineage: Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Acutalibacteraceae; UBA737; UBA737 sp900769375
• CAZyme ID: MGYG000003538_00021
• CAZy Family: GT4
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
382	MGYG000003538_6|CGC1	43205.82	7.7778

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003538	1465303	MAG	Fiji	Oceania

• Gene Location: Start: 549; End: 1697 Strand: +

Full Sequence      

MRFTDICEALVERGHSVTVVTGVPNYPEGEIYPDYRGGQRRKEKIGGVEVLRYATVPRKT
GTLFRILNYFSFAISAWLKAGKLADDYDVVLINQMSPVMMCWPGFRYARKHNKKCVMYCM
DLWPASLAAGEIKEDSLIYKVFKRISKRIYRRADKILITSRMFQDYFDEQFNITGDKIEY
LPQYADSQFEEKLSSGEEKSTVDLMFAGNIGAAQSIYTILGAAELLKEEKNVFWHIVGDG
SELKAAKNFCTNLNLENVIFYGRRPIDEMPELYSKADAMIVTLTGDPFISMTLPGKVQTY
MAAGKPILAAARGEIPSVLSDSGCGLCCEADNAEAFAELAKDFIKSTDKKNFALKARAYY
EANFTRRAFVDKLELTLKEHCK

Enzyme Prediction     

No EC number prediction in MGYG000003538_00021.

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
cd03794	GT4_WbuB-like	2.00e-97	2	374	19	391	Escherichia coli WbuB and similar proteins. This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.
cd03801	GT4_PimA-like	8.43e-34	2	374	19	362	phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.
PRK10307	PRK10307	1.40e-32	6	378	24	406	colanic acid biosynthesis glycosyltransferase WcaI.
COG0438	RfaB	1.68e-30	1	379	19	376	Glycosyltransferase involved in cell wall bisynthesis [Cell wall/membrane/envelope biogenesis].
cd03817	GT4_UGDG-like	3.00e-23	7	361	24	370	UDP-Glc:1,2-diacylglycerol 3-a-glucosyltransferase and similar proteins. This family is most closely related to the GT1 family of glycosyltransferases. UDP-glucose-diacylglycerol glucosyltransferase (EC 2.4.1.337, UGDG; also known as 1,2-diacylglycerol 3-glucosyltransferase) catalyzes the transfer of glucose from UDP-glucose to 1,2-diacylglycerol forming 3-D-glucosyl-1,2-diacylglycerol.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CAB1243732.1	6.04e-140	2	378	16	391
AEF17826.1	2.99e-137	2	374	16	395
AWE06755.1	1.83e-126	2	377	16	390
CAI33250.1	1.99e-126	2	379	16	404
BBG80873.1	1.99e-126	2	379	16	404

PDB Hits     

has no PDB hit.

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q8KIU8	2.31e-22	63	372	75	386	Probable glycosyltransferase WbjE OS=Pseudomonas aeruginosa OX=287 GN=wbjE PE=3 SV=2
P32057	1.57e-16	5	335	23	366	Putative colanic acid biosynthesis glycosyl transferase WcaI OS=Escherichia coli (strain K12) OX=83333 GN=wcaI PE=4 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000053	0.000001	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000003538_00021.