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CAZyme Information: MGYG000003413_00819
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Akkermansia sp900766865 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Verrucomicrobiota; Verrucomicrobiae; Verrucomicrobiales; Akkermansiaceae; Akkermansia; Akkermansia sp900766865 | |||||||||||
| CAZyme ID | MGYG000003413_00819 | |||||||||||
| CAZy Family | GH29 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 1842; End: 3731 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH29 | 21 | 315 | 1.4e-73 | 0.8526011560693642 |
| CBM32 | 507 | 622 | 4.1e-20 | 0.8790322580645161 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| COG3669 | AfuC | 4.03e-65 | 10 | 474 | 3 | 429 | Alpha-L-fucosidase [Carbohydrate transport and metabolism]. |
| pfam01120 | Alpha_L_fucos | 3.48e-42 | 29 | 314 | 44 | 326 | Alpha-L-fucosidase. |
| smart00812 | Alpha_L_fucos | 5.06e-36 | 29 | 314 | 45 | 328 | Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. |
| pfam00754 | F5_F8_type_C | 1.36e-16 | 511 | 621 | 14 | 127 | F5/8 type C domain. This domain is also known as the discoidin (DS) domain family. |
| pfam00754 | F5_F8_type_C | 5.09e-08 | 330 | 461 | 2 | 113 | F5/8 type C domain. This domain is also known as the discoidin (DS) domain family. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QWP61293.1 | 1.26e-254 | 7 | 624 | 22 | 686 |
| QWP68630.1 | 1.26e-254 | 7 | 624 | 22 | 686 |
| QWP54114.1 | 1.26e-254 | 7 | 624 | 22 | 686 |
| QWP03420.1 | 1.26e-254 | 7 | 624 | 22 | 686 |
| QWP63826.1 | 1.26e-254 | 7 | 624 | 22 | 686 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5K9H_A | 8.90e-124 | 12 | 623 | 33 | 583 | Crystalstructure of a glycoside hydrolase 29 family member from an unknown rumen bacterium [unidentified] |
| 4ZRX_A | 3.98e-97 | 17 | 608 | 31 | 566 | Crystalstructure of a putative alpha-L-fucosidase (BACOVA_04357) from Bacteroides ovatus ATCC 8483 at 1.59 A resolution [Bacteroides ovatus ATCC 8483] |
| 6ORG_A | 1.14e-87 | 12 | 479 | 5 | 452 | Crystalstructure of SpGH29 [Streptococcus pneumoniae TIGR4],6ORG_B Crystal structure of SpGH29 [Streptococcus pneumoniae TIGR4] |
| 6ORF_A | 1.72e-86 | 12 | 479 | 5 | 452 | Crystalstructure of SpGH29 [Streptococcus pneumoniae TIGR4],6ORF_B Crystal structure of SpGH29 [Streptococcus pneumoniae TIGR4] |
| 6OR4_A | 1.28e-85 | 12 | 478 | 5 | 451 | Crystalstructure of SpGH29 [Streptococcus pneumoniae TIGR4],6OR4_B Crystal structure of SpGH29 [Streptococcus pneumoniae TIGR4],6ORH_A Crystal structure of SpGH29 [Streptococcus pneumoniae TIGR4],6ORH_B Crystal structure of SpGH29 [Streptococcus pneumoniae TIGR4] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q8GW72 | 1.87e-87 | 11 | 476 | 31 | 478 | Alpha-L-fucosidase 1 OS=Arabidopsis thaliana OX=3702 GN=FUC1 PE=1 SV=2 |
| Q7XUR3 | 4.32e-84 | 1 | 474 | 23 | 475 | Putative alpha-L-fucosidase 1 OS=Oryza sativa subsp. japonica OX=39947 GN=Os04g0560400 PE=3 SV=2 |
| P49713 | 1.84e-12 | 54 | 314 | 90 | 340 | Putative alpha-L-fucosidase OS=Caenorhabditis elegans OX=6239 GN=W03G11.3 PE=3 SV=2 |
| I1S2N3 | 7.37e-11 | 495 | 627 | 49 | 190 | Galactose oxidase OS=Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) OX=229533 GN=GAOA PE=3 SV=1 |
| P17164 | 8.87e-11 | 32 | 314 | 84 | 356 | Tissue alpha-L-fucosidase OS=Rattus norvegicus OX=10116 GN=Fuca1 PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.994154 | 0.005849 | 0.000016 | 0.000011 | 0.000006 | 0.000011 |