Species | CAG-495 sp900762585 | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Lineage | Bacteria; Proteobacteria; Alphaproteobacteria; RF32; CAG-239; CAG-495; CAG-495 sp900762585 | |||||||||||
CAZyme ID | MGYG000003285_01190 | |||||||||||
CAZy Family | GH23 | |||||||||||
CAZyme Description | Membrane-bound lytic murein transglycosylase C | |||||||||||
CAZyme Property |
|
|||||||||||
Genome Property |
|
|||||||||||
Gene Location | Start: 28044; End: 29801 Strand: + |
Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
---|---|---|---|---|---|---|---|
cd13401 | Slt70-like | 6.68e-51 | 416 | 564 | 1 | 152 | 70kDa soluble lytic transglycosylase (Slt70) and similar proteins. Catalytic domain of the 70kda soluble lytic transglycosylase (LT)-like proteins, which also have an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda. |
cd00254 | LT-like | 2.76e-34 | 432 | 559 | 2 | 111 | lytic transglycosylase(LT)-like domain. Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. |
cd16896 | LT_Slt70-like | 9.89e-33 | 432 | 558 | 20 | 144 | uncharacterized lytic transglycosylase subfamily with similarity to Slt70. Uncharacterized lytic transglycosylase (LT) with a conserved sequence pattern suggesting similarity to the Slt70, a 70kda soluble lytic transglycosylase which also has an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. |
COG0741 | MltE | 1.49e-25 | 424 | 574 | 147 | 296 | Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell wall/membrane/envelope biogenesis]. |
PRK11619 | PRK11619 | 1.99e-24 | 266 | 569 | 342 | 632 | lytic murein transglycosylase; Provisional |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
---|---|---|---|---|---|
QIM10634.1 | 5.97e-150 | 33 | 581 | 28 | 575 |
AUG55166.1 | 1.09e-102 | 47 | 581 | 65 | 601 |
CDL00242.1 | 2.33e-102 | 47 | 581 | 75 | 602 |
AVM75780.1 | 2.33e-102 | 47 | 581 | 75 | 602 |
AVM79683.1 | 2.33e-102 | 47 | 581 | 75 | 602 |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
5MPQ_A | 7.44e-23 | 246 | 566 | 247 | 560 | BulgecinA: The key to a broad-spectrum inhibitor that targets lytic transglycosylases [Neisseria meningitidis] |
5O1J_A | 7.56e-23 | 246 | 566 | 251 | 564 | Lytictransglycosylase in action [Neisseria meningitidis MC58] |
6FPN_B | 7.73e-23 | 246 | 566 | 257 | 570 | Lytictransglycosylase in action [Neisseria meningitidis MC58] |
5O24_A | 7.84e-23 | 246 | 566 | 261 | 574 | Lytictransglycosylase in action [Neisseria meningitidis] |
5O29_A | 8.00e-23 | 246 | 566 | 267 | 580 | Lytictransglycosylase in action [Neisseria meningitidis] |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
P39434 | 8.92e-22 | 265 | 568 | 341 | 632 | Soluble lytic murein transglycosylase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=slt PE=3 SV=2 |
P0AGC3 | 4.90e-21 | 265 | 569 | 341 | 633 | Soluble lytic murein transglycosylase OS=Escherichia coli (strain K12) OX=83333 GN=slt PE=1 SV=1 |
P0AGC4 | 4.90e-21 | 265 | 569 | 341 | 633 | Soluble lytic murein transglycosylase OS=Escherichia coli O157:H7 OX=83334 GN=slt PE=3 SV=1 |
O31608 | 1.51e-14 | 425 | 559 | 69 | 180 | Putative murein lytic transglycosylase YjbJ OS=Bacillus subtilis (strain 168) OX=224308 GN=yjbJ PE=3 SV=1 |
O31976 | 1.53e-12 | 427 | 558 | 1433 | 1541 | SPbeta prophage-derived uncharacterized transglycosylase YomI OS=Bacillus subtilis (strain 168) OX=224308 GN=yomI PE=3 SV=2 |
Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
---|---|---|---|---|---|
0.002041 | 0.748093 | 0.248781 | 0.000421 | 0.000346 | 0.000295 |
Copyright 2022 © YIN LAB, UNL. All rights reserved. Designed by Jinfang Zheng and Boyang Hu. Maintained by Yanbin Yin.