Species | Winkia neuii | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Lineage | Bacteria; Actinobacteriota; Actinomycetia; Actinomycetales; Actinomycetaceae; Winkia; Winkia neuii | |||||||||||
CAZyme ID | MGYG000003130_00472 | |||||||||||
CAZy Family | GT39 | |||||||||||
CAZyme Description | putative dolichyl-phosphate-mannose--protein mannosyltransferase | |||||||||||
CAZyme Property |
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Genome Property |
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Gene Location | Start: 479464; End: 480852 Strand: + |
Family | Start | End | Evalue | family coverage |
---|---|---|---|---|
GT39 | 1 | 259 | 6.5e-62 | 0.9775784753363229 |
Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
---|---|---|---|---|---|---|---|
COG1928 | PMT1 | 7.87e-18 | 2 | 272 | 34 | 316 | Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]. |
pfam16192 | PMT_4TMC | 2.35e-10 | 275 | 458 | 1 | 197 | C-terminal four TMM region of protein-O-mannosyltransferase. PMT_4TMC is the C-terminal four membrane-pass region of protein-O-mannosyltransferases and similar enzymes. |
COG4346 | COG4346 | 1.06e-09 | 64 | 400 | 136 | 406 | Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase [Posttranslational modification, protein turnover, chaperones]. |
pfam02366 | PMT | 5.05e-09 | 1 | 154 | 6 | 152 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families. |
COG1807 | ArnT | 0.007 | 64 | 169 | 64 | 167 | 4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family [Cell wall/membrane/envelope biogenesis]. |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
---|---|---|---|---|---|
QOX81378.1 | 7.47e-126 | 1 | 462 | 60 | 547 |
QIN29095.1 | 4.16e-103 | 1 | 462 | 76 | 568 |
QCT34948.1 | 7.29e-101 | 1 | 462 | 78 | 581 |
QGS11599.1 | 2.87e-100 | 1 | 462 | 78 | 581 |
BAU99550.1 | 7.52e-99 | 1 | 462 | 1 | 489 |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
6P25_B | 1.43e-08 | 1 | 208 | 74 | 262 | Structureof S. cerevisiae protein O-mannosyltransferase Pmt1-Pmt2 complex bound to the sugar donor and a peptide acceptor [Saccharomyces cerevisiae W303],6P2R_B Structure of S. cerevisiae protein O-mannosyltransferase Pmt1-Pmt2 complex bound to the sugar donor [Saccharomyces cerevisiae W303] |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
P9WN04 | 1.67e-50 | 1 | 461 | 53 | 521 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pmt PE=3 SV=2 |
P9WN05 | 1.67e-50 | 1 | 461 | 53 | 521 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=pmt PE=1 SV=2 |
L8F4Z2 | 1.46e-46 | 1 | 461 | 47 | 515 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycolicibacterium smegmatis (strain MKD8) OX=1214915 GN=pmt PE=3 SV=1 |
Q8NRZ6 | 1.00e-42 | 17 | 461 | 63 | 519 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) OX=196627 GN=pmt PE=3 SV=1 |
Q8BGQ4 | 1.51e-08 | 6 | 208 | 142 | 325 | Protein O-mannosyl-transferase 2 OS=Mus musculus OX=10090 GN=Pomt2 PE=1 SV=1 |
Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
---|---|---|---|---|---|
1.000047 | 0.000007 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |
start | end |
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136 | 155 |
176 | 195 |
199 | 221 |
228 | 250 |
330 | 352 |
359 | 378 |
383 | 405 |
425 | 447 |
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