CAZyme Information: MGYG000003120_01289

Basic Information

• Species: Alloscardovia omnicolens
• Lineage: Bacteria; Actinobacteriota; Actinomycetia; Actinomycetales; Bifidobacteriaceae; Alloscardovia; Alloscardovia omnicolens
• CAZyme ID: MGYG000003120_01289
• CAZy Family: GH2
• CAZyme Description: Beta-galactosidase BoGH2A

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
856	MGYG000003120_43|CGC1	95056.55	5.1482

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003120	1680436	MAG	United States	North America

• Gene Location: Start: 4092; End: 6662 Strand: -

Full Sequence      

MRVSTFNEGWSYRRFNAEMGYPDDTDFTAVSIPHDAMLYEKRSQLASSGTNGSWFEGADY
EYVKHFAVSEDAPAVQWLEFEGVYHNAEVWLNGEKLAFRPYGYTNFYVDISSHVKRRPGA
GEPVNDSLNESLNESLNEPLNELRVIARNVDQPNSRWYSGAGIYRPVQLWTAESAEHIVH
NGVTVRTVSVDGQRARLWVQVNATAAGTATISIPQMGDSTQSDNAQDNNSVVTHSLRVEA
QTDASAQGSIAQGSIEFDVEGVQLWSLDNPYVYEMHVDYVSDNGSRDQATTTFGVRTISW
GDEGFLLNGKRVIIQGACIHHDNGVLGAATYAQAEERRVRLMKKAGYNAIRSAHNPISKA
LLDACDKLGVLVMDEYIDHWYIHKTQHDYVDYFDQWWQQDLRDMVEKDKNHPSVIMYSTG
NEVAETAQKRGIELTAQMTEFLHSLDNTRPVTCGINIFFNFLNKIGFGQYSDEKAAKEAE
EAARRKAAGEGEAVKHKASGSEFFNNLAGIMGADFMKIGASLPSCDWVTRDAFAAMDIAG
YNYGINRYKHDLKKYEHRLILGSETFCNDAHKFRELAKKEPRLIGDFVWAGMDYLGETGV
GGWEYADYAPREQKCGWLTAGSGRVDLIGNFLGEAYYTRVALESEGDQGPYIAVVPVNHT
HDKHSPSAWKMSNAIASWSWNGCEGEDARVEVYARAASVALLVNGVEVGRKKMRGDCIAR
FNTTWQPGVVEAVSYDVSGKEIGRYALHSAGETTRLTASCEPESENSRVKFIHVDYTDNA
GEVKPLERGQLSASVEGKGVRLLGFGCASPYNEASFVSGESGTYYGRALAVVEVPEDATG
RLIVRDNHGRTAQLDL

Enzyme Prediction     

EC	3.2.1.-

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH2	3	608	1e-94	0.5904255319148937

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG3250	LacZ	1.33e-54	78	452	103	430	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
PRK10150	PRK10150	3.32e-35	78	472	86	465	beta-D-glucuronidase; Provisional
PRK10340	ebgA	1.22e-25	62	451	113	472	cryptic beta-D-galactosidase subunit alpha; Reviewed
pfam02836	Glyco_hydro_2_C	2.90e-21	302	453	5	160	Glycosyl hydrolases family 2, TIM barrel domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.
pfam16355	DUF4982	1.34e-13	685	744	1	61	Domain of unknown function (DUF4982). This family is found in the C-terminal of uncharacterized proteins and beta-galactosidases around 680 residues in length from various Bacteroides species. The function of this protein is unknown.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QTL78050.1	0.0	1	850	15	830
QTL79929.1	0.0	1	850	15	830
ADB08903.1	0.0	1	850	1	816
BAQ26204.1	0.0	1	850	1	816
VEG22877.1	0.0	1	850	1	816

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6B6L_A	3.09e-109	1	844	5	761	Thecrystal structure of glycosyl hydrolase family 2 (GH2) member from Bacteroides cellulosilyticus DSM 14838 [Bacteroides cellulosilyticus DSM 14838],6B6L_B The crystal structure of glycosyl hydrolase family 2 (GH2) member from Bacteroides cellulosilyticus DSM 14838 [Bacteroides cellulosilyticus DSM 14838]
7RSK_A	4.64e-109	1	844	5	761	ChainA, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7RSK_B Chain B, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838]
4YPJ_A	1.80e-80	2	833	8	781	ChainA, Beta galactosidase [Niallia circulans],4YPJ_B Chain B, Beta galactosidase [Niallia circulans]
7CWD_A	1.22e-77	1	833	1	775	ChainA, beta-glalactosidase [Niallia circulans],7CWI_A Chain A, beta-galactosidase [Niallia circulans]
5T98_A	6.84e-77	5	842	29	802	Crystalstructure of BuGH2Awt [Bacteroides uniformis],5T98_B Crystal structure of BuGH2Awt [Bacteroides uniformis],5T99_A Crystal structure of BuGH2Awt in complex with Galactoisofagomine [Bacteroides uniformis],5T99_B Crystal structure of BuGH2Awt in complex with Galactoisofagomine [Bacteroides uniformis]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
A7LXS9	1.68e-82	4	833	45	822	Beta-galactosidase BoGH2A OS=Bacteroides ovatus (strain ATCC 8483 / DSM 1896 / JCM 5824 / BCRC 10623 / CCUG 4943 / NCTC 11153) OX=411476 GN=BACOVA_02645 PE=1 SV=1
T2KM09	1.45e-63	23	797	71	758	Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_22050 PE=2 SV=2
P77989	2.09e-24	3	450	5	411	Beta-galactosidase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) OX=340099 GN=lacZ PE=3 SV=2
T2KPJ7	5.16e-23	23	471	75	491	Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_21970 PE=2 SV=1
P26257	4.34e-20	2	460	3	421	Beta-galactosidase OS=Thermoanaerobacterium thermosulfurigenes OX=33950 GN=lacZ PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000055	0.000000	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000003120_01289.