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CAZyme Information: MGYG000003097_00348

You are here: Home > Sequence: MGYG000003097_00348

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Phocaeicola sp000436795
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Phocaeicola; Phocaeicola sp000436795
CAZyme ID MGYG000003097_00348
CAZy Family CE2
CAZyme Description Cellulase/esterase CelE
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
368 MGYG000003097_2|CGC3 41246.03 6.6062
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003097 3921942 MAG Spain Europe
Gene Location Start: 176208;  End: 177314  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000003097_00348.

CAZyme Signature Domains help

Family Start End Evalue family coverage
CE2 155 362 2e-64 0.9952153110047847

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd01831 Endoglucanase_E_like 1.15e-40 155 363 1 169
Endoglucanase E-like members of the SGNH hydrolase family; Endoglucanase E catalyzes the endohydrolysis of 1,4-beta-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
pfam17996 CE2_N 7.30e-35 44 149 1 108
Carbohydrate esterase 2 N-terminal. This is the N-terminal beta-sheet domain with jelly roll topology found in CE2 acetyl-esterase from the bacterium Clostridium thermocellum. This enzyme displays dual activities, it catalyses the deacetylation of plant polysaccharides and also potentiates the activity of its appended cellulase catalytic module through its noncatalytic cellulose binding function. This N-terminal jelly-roll domain appears to extend the substrate/cellulose binding cleft of the catalytic domain in C.thermocellum.
cd00229 SGNH_hydrolase 8.43e-11 156 361 1 187
SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxlic acid.
pfam13472 Lipase_GDSL_2 4.09e-10 158 320 1 131
GDSL-like Lipase/Acylhydrolase family. This family of presumed lipases and related enzymes are similar to pfam00657.
cd01833 XynB_like 6.93e-06 247 294 39 85
SGNH_hydrolase subfamily, similar to Ruminococcus flavefaciens XynB. Most likely a secreted hydrolase with xylanase activity. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
ADY36201.1 8.16e-188 23 368 24 369
QNT66876.1 3.94e-116 25 368 26 370
ADE83543.1 3.76e-115 10 368 4 375
QVJ79798.1 7.54e-115 10 368 4 375
QCD38714.1 4.12e-113 15 363 10 356

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
2WAO_A 1.45e-48 38 368 7 333
ChainA, ENDOGLUCANASE E [Acetivibrio thermocellus]
2WAB_A 4.00e-48 38 368 7 333
ChainA, ENDOGLUCANASE E [Acetivibrio thermocellus]
2WAA_A 7.53e-32 23 368 1 339
Structureof a family two carbohydrate esterase from Cellvibrio japonicus [Cellvibrio japonicus]
4XVH_A 9.06e-27 44 347 4 308
Crystalstructure of a Corynascus thermopiles (Myceliophthora fergusii) carbohydrate esterase family 2 (CE2) enzyme plus carbohydrate binding domain (CBD) [Chaetomium]
2W9X_A 4.20e-26 12 362 6 353
Theactive site of a carbohydrate esterase displays divergent catalytic and non-catalytic binding functions [Cellvibrio japonicus],2W9X_B The active site of a carbohydrate esterase displays divergent catalytic and non-catalytic binding functions [Cellvibrio japonicus]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P10477 2.28e-45 31 368 481 814
Cellulase/esterase CelE OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=celE PE=1 SV=2
B3PIB0 5.03e-31 10 368 4 358
Acetylxylan esterase / glucomannan deacetylase OS=Cellvibrio japonicus (strain Ueda107) OX=498211 GN=axe2C PE=1 SV=1
B3PDE5 2.11e-25 12 362 6 353
Acetylxylan esterase / glucomannan deacetylase OS=Cellvibrio japonicus (strain Ueda107) OX=498211 GN=ce2C PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000443 0.998554 0.000340 0.000225 0.000217 0.000192

TMHMM  Annotations      download full data without filtering help

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