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CAZyme Information: MGYG000003063_00445
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Eisenbergiella sp900544445 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Eisenbergiella; Eisenbergiella sp900544445 | |||||||||||
| CAZyme ID | MGYG000003063_00445 | |||||||||||
| CAZy Family | GH28 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 30357; End: 32747 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH28 | 354 | 729 | 8.3e-57 | 0.9292307692307692 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| COG5434 | Pgu1 | 3.87e-37 | 330 | 652 | 80 | 394 | Polygalacturonase [Carbohydrate transport and metabolism]. |
| PLN03003 | PLN03003 | 4.54e-10 | 489 | 657 | 137 | 297 | Probable polygalacturonase At3g15720 |
| pfam00295 | Glyco_hydro_28 | 1.49e-09 | 493 | 646 | 87 | 273 | Glycosyl hydrolases family 28. Glycosyl hydrolase family 28 includes polygalacturonase EC:3.2.1.15 as well as rhamnogalacturonase A(RGase A), EC:3.2.1.-. These enzymes are important in cell wall metabolism. |
| PLN02218 | PLN02218 | 3.27e-09 | 359 | 657 | 95 | 351 | polygalacturonase ADPG |
| cd08978 | GH_F | 7.09e-09 | 21 | 239 | 1 | 230 | Glycosyl hydrolase families 43 and 62 form CAZY clan GH-F. This glycosyl hydrolase clan F (according to carbohydrate-active enzymes database (CAZY)) includes family 43 (GH43) and 62 (GH62). GH43 includes enzymes with beta-xylosidase (EC 3.2.1.37), beta-1,3-xylosidase (EC 3.2.1.-), alpha-L-arabinofuranosidase (EC 3.2.1.55), arabinanase (EC 3.2.1.99), xylanase (EC 3.2.1.8), endo-alpha-L-arabinanases (beta-xylanases) and galactan 1,3-beta-galactosidase (EC 3.2.1.145) activities. GH62 includes enzymes characterized as arabinofuranosidases (alpha-L-arabinofuranosidases; EC 3.2.1.55) that specifically cleave either alpha-1,2 or alpha-1,3-L-arabinofuranose side chains from xylans. GH43 are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Many of the enzymes in this family display both alpha-L-arabinofuranosidase and beta-D-xylosidase activity using aryl-glycosides as substrates. GH62 are also predicted to be inverting enzymes. A common structural feature of both, GH43 and GH62 enzymes, is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AOZ96985.1 | 8.09e-133 | 303 | 789 | 11 | 528 |
| QDA61631.1 | 2.67e-87 | 1 | 286 | 23 | 317 |
| CCW36339.1 | 3.08e-51 | 334 | 795 | 31 | 470 |
| QGT72757.1 | 5.81e-49 | 331 | 793 | 50 | 466 |
| QEE27992.1 | 1.99e-48 | 328 | 794 | 26 | 461 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5OLP_A | 5.51e-28 | 330 | 724 | 42 | 422 | Galacturonidase[Bacteroides thetaiotaomicron VPI-5482],5OLP_B Galacturonidase [Bacteroides thetaiotaomicron VPI-5482] |
| 3JUR_A | 6.22e-15 | 317 | 608 | 12 | 312 | Thecrystal structure of a hyperthermoactive Exopolygalacturonase from Thermotoga maritima [Thermotoga maritima],3JUR_B The crystal structure of a hyperthermoactive Exopolygalacturonase from Thermotoga maritima [Thermotoga maritima],3JUR_C The crystal structure of a hyperthermoactive Exopolygalacturonase from Thermotoga maritima [Thermotoga maritima],3JUR_D The crystal structure of a hyperthermoactive Exopolygalacturonase from Thermotoga maritima [Thermotoga maritima] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q02096 | 3.66e-09 | 408 | 657 | 165 | 365 | Polygalacturonase OS=Persea americana OX=3435 PE=2 SV=1 |
| P26216 | 2.95e-08 | 320 | 732 | 30 | 385 | Exopolygalacturonase OS=Zea mays OX=4577 GN=PG1 PE=1 SV=1 |
| P35338 | 2.95e-08 | 320 | 664 | 30 | 330 | Exopolygalacturonase OS=Zea mays OX=4577 GN=PG9 PE=2 SV=1 |
| P58598 | 5.12e-08 | 341 | 655 | 67 | 395 | Polygalacturonase OS=Ralstonia solanacearum (strain GMI1000) OX=267608 GN=pglA PE=3 SV=1 |
| P49062 | 3.80e-07 | 332 | 666 | 51 | 338 | Exopolygalacturonase clone GBGE184 OS=Arabidopsis thaliana OX=3702 GN=PGA3 PE=2 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000073 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |