CAZyme Information: MGYG000002737_01575

Basic Information

• Species: Prevotella sp900553465
• Lineage: Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Prevotella; Prevotella sp900553465
• CAZyme ID: MGYG000002737_01575
• CAZy Family: GH115
• CAZyme Description: hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
1296	MGYG000002737_53|CGC1	144460.35	4.7042

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002737	2443712	MAG	Netherlands	Europe

• Gene Location: Start: 11707; End: 15597 Strand: +

Full Sequence      

MRKIFSFIFIAAMTALTAGNACAQNAITVSETEQSGSFPIVGDDGTTATIVFDKNDAQVV
ETAATALAGDIKAVTGKEIKVGTELTAGSSPIIAGTIGSSELIDRLAAEGKIDVSDVKGK
WEAYGLQTVDNPTEGVDRALVLFGSTPRGTAYAIFEVSRLMGVSPYIWWADVVPAHKDRL
YASAGRSVTGEPSVKYRGIFINDEDWGFQPWAAKNMDPDRNNVGPNSYAKVMELLLRLRA
NTLWPAMHLCSEAFWANKANLPVAKKYDIVLGSSHCEQMLRDNEWEWRRWGDGTGTYENW
NYVTNKEKIQQYWEERVIESKGFDAMYTTGMRGVHDWGISGYPTTQDKVRGLTEIIGFQR
QLLEKHIGDPTTVPQIFIPYKEVLEAYNAGLQVPEDITLTWVDDNHGYIRQMPTKSEQAR
SGGNGIYYHLSYWGTPQDYLWLCSTSPSLISYELSKGYDYGIRTLWIINVGDIKPAEAEL
EFCMDLAWDVERWNPEEAHKYSRYWAAKTFGEEYADELSDIKQEYYRLGAGGKPEHIFAV
NYTDEEKDRRIADYKNIVDKVDNLKARIPSELQDAYFEMIEYPVKGAYYMNVKTFRAAQS
LVLAKAGQRDKALEYAAEARKAYRQIEQITNKYNNEIAGGKWNEMMDSKPRQQSQFYMPE
TATLSNISSVQKEIEKEQTFAVAADKYTSTRGNIVTLEGLGVGGNSVTVWPINETVYSAD
KAGSAPYAEYDVEVKSGANMISARCLPTFPINSSFDLRVAISVDGGEPQVCSLKTTATEG
KWNTTVLQGFNDATVTYNADEDKTVSVRVYMLDPGVVLSEIYNRLPESADNSLTVKLIKN
NDFELRTDGTPNPQGNTDRGIPYGWDHTGELTLGQNGLPSYGINQDAANLHGSNVCWINS
FPMPEFFELSQTIPASEIEPGTYRVSCMMWMEENKKASGRLFANNNVQYYGSESDYTRLL
TPGEVNTYAGHAGQNGAGPFNLMPMEVYVTVTEGEDLKLGIRSGNKRNDGTTATDNAGWF
KVDNFRIEKVSGMPEPQEEDLTLTKQLITNYDFELYDDNGTIKENTSGDTRRGTIYGIHG
WKVAGRFPGDSYGINKDASNPHATNVCWFQAKNGNMPDDFALYQTIPADKLTPGRYMICC
RLWAEEGFLSTVRLFANDNVQYYGMDIDYDKNLTPGEHNTFAGYIGGAPNTFVLQDMYVY
VDIEEGDDLKFGIRSSNTNADGTKGTDVKNGWFKTDFFRIHKVDDTNGIGTPTAGTGRTA
KGVYNIKGQKVGAELSDNHNLPSGIYVVDGRKTVVR

Enzyme Prediction     

EC	3.2.1.-

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH115	43	821	7.9e-232	0.9885222381635581

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam15979	Glyco_hydro_115	3.89e-166	190	536	1	334	Glycosyl hydrolase family 115. Glyco_hydro_115 is a family of glycoside hydrolases likely to have the activity of xylan a-1,2-glucuronidase, EC:3.2.1.131, or a-(4-O-methyl)-glucuronidase EC:3.2.1.-.
pfam17829	GH115_C	5.61e-19	684	818	13	153	Gylcosyl hydrolase family 115 C-terminal domain. This domain is found at the C-terminus of glycosyl hydrolase family 115 proteins. This domain has a beta-sandwich fold.
pfam03648	Glyco_hydro_67N	0.001	48	156	22	119	Glycosyl hydrolase family 67 N-terminus. Alpha-glucuronidases, components of an ensemble of enzymes central to the recycling of photosynthetic biomass, remove the alpha-1,2 linked 4-O-methyl glucuronic acid from xylans. This family represents the N-terminal region of alpha-glucuronidase. The N-terminal domain forms a two-layer sandwich, each layer being formed by a beta sheet of five strands. A further two helices form part of the interface with the central, catalytic, module (pfam07488).

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QNR82970.1	4.50e-260	20	821	22	830
QIL38270.1	2.44e-259	23	821	24	829
ARS42990.1	1.57e-254	20	821	22	830
QNN40531.1	1.33e-253	27	821	32	832
ADY54265.1	3.15e-253	27	821	26	827

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
5BY3_A	5.34e-161	45	821	25	771	Anovel family GH115 4-O-Methyl-alpha-glucuronidase, BtGH115A, with specificity for decorated arabinogalactans [Bacteroides thetaiotaomicron VPI-5482]
4ZMH_A	2.16e-108	48	643	23	607	Crystalstructure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40],4ZMH_B Crystal structure of a five-domain GH115 alpha-Glucuronidase from the Marine Bacterium Saccharophagus degradans 2-40T [Saccharophagus degradans 2-40]
4C90_A	1.32e-103	1	649	12	643	Evidencethat GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C90_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_A Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus],4C91_B Evidence that GH115 alpha-glucuronidase activity is dependent on conformational flexibility [Bacteroides ovatus]
7PUG_A	7.26e-96	45	649	23	628	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]
7PXQ_A	3.14e-94	45	649	22	627	ChainA, xylan alpha-1,2-glucuronidase [uncultured bacterium]

Swiss-Prot Hits     

has no Swissprot hit.

SignalP and Lipop Annotations

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000757	0.991419	0.007064	0.000290	0.000217	0.000206

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002737_01575.