CAZyme Information: MGYG000002699_01705

Basic Information

• Lineage: Bacteria; Firmicutes_A; Clostridia_A; Christensenellales; CAG-74; HGM11588
• CAZyme ID: MGYG000002699_01705
• CAZy Family: GH2
• CAZyme Description: Beta-galactosidase BoGH2A

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
775	MGYG000002699_32|CGC1	87091.24	6.3522

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002699	3362623	MAG	Canada	North America

• Gene Location: Start: 9482; End: 11809 Strand: +

Full Sequence      

MREKLLWNADWLFCAEALPARAFSVKGPMYKQAKTERVRTGPAARMHNDAVDDYRDGVEY
SPERWEKVDLPHDFVIDGLPEARGNNARGFFAYGDGWYRKHFTLPPSDAGRRITLYFEGV
ATWATVYLNGCLLKRNFCGYTPFEVDITDLVEFGADNVLAVHVETGESEGWWYDGGGIYR
NVYLVKTDRVAVDLYGAYVAPRKLKEDLWRVPVEITLRNDGYAACEAEAQVSLVDEAGAI
AAVASATGSLPARGKATLLCEAQVRAPRLWDVDAPHLYRAAVSVYVAGELRDQYETRFGF
RTVYADPQKGLFLNGKPVKIQGVCAHADFGLSGKAVPDNILRWKVRRIREMGANGYRTSH
YPHAEATMDALDEMGFLVMDETRWFESSEDGLEQLRTLVRRDRNRPSVLFWSTSNEEDLH
VSPIGRNIHRAMAAEIRKLDDTRLITAAISVRPDRATLGGDLDAIGVNYNFPLWDPIHEK
WPQTPVFISECCATGTTRGWYWPDSAEHAYLSAYDRDTNESFLGREKTWKAVMARPWLLG
AYQWIAFEHRGEAVWPRLCSQSGAIDLFMQNKDAFYQNQSHWTSAPMVHILPHWNHAGRE
GETIAVWAYTNCEEVELWLNGRSQGRRRIERFGHGEWQVTYEPGEVMAVGYVDGMERVRE
TVRTSGPAAALKLVAEDTRATANGQDIAVFTCLAVDAQGREVPDASATVTFFASPLGRIV
GAGSDISQHKRLSDPVVRMRAGRAAVAIRLGREHGTLRVMARADGWQSAYCALEI

Enzyme Prediction     

No EC number prediction in MGYG000002699_01705.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH2	60	556	1.3e-101	0.5598404255319149

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG3250	LacZ	1.46e-52	62	552	31	505	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].
PRK10150	PRK10150	6.40e-50	50	468	22	470	beta-D-glucuronidase; Provisional
PRK10340	ebgA	8.29e-38	96	445	111	472	cryptic beta-D-galactosidase subunit alpha; Reviewed
pfam02836	Glyco_hydro_2_C	5.00e-29	309	446	5	159	Glycosyl hydrolases family 2, TIM barrel domain. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities.
PRK09525	lacZ	1.23e-24	96	443	122	483	beta-galactosidase.

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QYY34329.1	4.56e-274	1	775	1	776
CCW36355.1	3.28e-167	20	774	162	934
ADG11711.1	2.64e-163	59	769	92	823
AVQ03353.1	2.64e-163	59	769	92	823
QUD88293.1	5.07e-163	2	730	34	770

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
7CWD_A	2.81e-110	60	768	28	794	ChainA, beta-glalactosidase [Niallia circulans],7CWI_A Chain A, beta-galactosidase [Niallia circulans]
4YPJ_A	5.34e-108	36	768	19	800	ChainA, Beta galactosidase [Niallia circulans],4YPJ_B Chain B, Beta galactosidase [Niallia circulans]
5T98_A	4.03e-105	56	775	45	820	Crystalstructure of BuGH2Awt [Bacteroides uniformis],5T98_B Crystal structure of BuGH2Awt [Bacteroides uniformis],5T99_A Crystal structure of BuGH2Awt in complex with Galactoisofagomine [Bacteroides uniformis],5T99_B Crystal structure of BuGH2Awt in complex with Galactoisofagomine [Bacteroides uniformis]
4CU6_A	9.05e-91	65	721	43	784	Unravellingthe multiple functions of the architecturally intricate Streptococcus pneumoniae beta-galactosidase, BgaA [Streptococcus pneumoniae TIGR4],4CU7_A Unravelling the multiple functions of the architecturally intricate Streptococcus pneumoniae beta-galactosidase, BgaA [Streptococcus pneumoniae TIGR4],4CU8_A Unravelling the multiple functions of the architecturally intricate Streptococcus pneumoniae beta-galactosidase, BgaA [Streptococcus pneumoniae TIGR4]
3GM8_A	1.83e-90	60	721	29	743	ChainA, Glycoside hydrolase family 2, candidate beta-glycosidase [Phocaeicola vulgatus ATCC 8482]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
A7LXS9	1.49e-105	60	769	66	842	Beta-galactosidase BoGH2A OS=Bacteroides ovatus (strain ATCC 8483 / DSM 1896 / JCM 5824 / BCRC 10623 / CCUG 4943 / NCTC 11153) OX=411476 GN=BACOVA_02645 PE=1 SV=1
T2KM09	5.61e-79	55	703	60	746	Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_22050 PE=2 SV=2
T2KN75	2.37e-67	58	774	48	794	Beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_22060 PE=1 SV=1
P77989	1.35e-59	73	763	31	725	Beta-galactosidase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) OX=340099 GN=lacZ PE=3 SV=2
T2KPJ7	6.65e-41	65	774	79	824	Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_21970 PE=2 SV=1

SignalP and Lipop Annotations

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000041	0.000012	0.000000	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002699_01705.