Species | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Rikenellaceae; Alistipes; | |||||||||||
CAZyme ID | MGYG000002674_00248 | |||||||||||
CAZy Family | PL13 | |||||||||||
CAZyme Description | Heparin lyase I | |||||||||||
CAZyme Property |
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Genome Property |
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Gene Location | Start: 11840; End: 12985 Strand: - |
Family | Start | End | Evalue | family coverage |
---|---|---|---|---|
PL13 | 24 | 377 | 4e-174 | 0.9834710743801653 |
Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
---|---|---|---|---|---|---|---|
pfam14099 | Polysacc_lyase | 4.83e-12 | 69 | 365 | 28 | 200 | Polysaccharide lyase. This family includes heparin lyase I, EC:4.2.2.7. Heparin lyase I depolymerizes heparin by cleaving the glycosidic linkage next to an iduronic acid moiety. The structure of heparin lyase I consists of a beta-jelly roll domain with a long, deep substrate-binding groove and an unusual thumb domain containing many basic residues extending from the main body of the enzyme. This family also includes glucuronan lyase, EC:4.2.2.14. The structure glucuronan lyase is a beta-jelly roll. |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
---|---|---|---|---|---|
CBK62841.1 | 1.03e-198 | 8 | 379 | 2 | 377 |
ADL62736.1 | 7.63e-169 | 21 | 373 | 22 | 389 |
QUT82562.1 | 2.38e-165 | 23 | 378 | 25 | 392 |
QDM12118.1 | 2.38e-165 | 23 | 378 | 25 | 392 |
QRQ56254.1 | 6.80e-165 | 23 | 378 | 25 | 392 |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
3ILR_A | 1.32e-165 | 23 | 378 | 3 | 370 | Structureof Heparinase I from Bacteroides thetaiotaomicron in complex with tetrasaccharide product [Bacteroides thetaiotaomicron] |
3IKW_A | 1.52e-165 | 23 | 378 | 7 | 374 | Structureof Heparinase I from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron] |
3IMN_A | 9.52e-163 | 23 | 378 | 9 | 376 | Crystalstructure of heparin lyase I from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron],3IN9_A Crystal structure of heparin lyase I complexed with disaccharide heparin [Bacteroides thetaiotaomicron] |
3INA_A | 3.14e-161 | 23 | 378 | 9 | 376 | Crystalstructure of heparin lyase I H151A mutant complexed with a dodecasaccharide heparin [Bacteroides thetaiotaomicron] |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
Q05819 | 3.64e-149 | 19 | 377 | 19 | 381 | Heparin lyase I OS=Pedobacter heparinus OX=984 PE=1 SV=1 |
Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
---|---|---|---|---|---|
0.000357 | 0.998947 | 0.000204 | 0.000181 | 0.000159 | 0.000144 |
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