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CAZyme Information: MGYG000002620_01972
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Desulfovibrio desulfuricans | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Desulfobacterota; Desulfovibrionia; Desulfovibrionales; Desulfovibrionaceae; Desulfovibrio; Desulfovibrio desulfuricans | |||||||||||
| CAZyme ID | MGYG000002620_01972 | |||||||||||
| CAZy Family | GT21 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 40900; End: 42087 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT21 | 46 | 271 | 1.2e-21 | 0.9699570815450643 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam13506 | Glyco_transf_21 | 2.26e-33 | 105 | 275 | 6 | 174 | Glycosyl transferase family 21. This is a family of ceramide beta-glucosyltransferases - EC:2.4.1.80. |
| cd02520 | Glucosylceramide_synthase | 5.36e-16 | 46 | 271 | 1 | 190 | Glucosylceramide synthase catalyzes the first glycosylation step of glycosphingolipid synthesis. UDP-glucose:N-acylsphingosine D-glucosyltransferase (glucosylceramide synthase or ceramide glucosyltransferase) catalyzes the first glycosylation step of glycosphingolipid synthesis. Its product, glucosylceramide, serves as the core of more than 300 glycosphingolipids (GSL). GSLs are a group of membrane components that have the lipid portion embedded in the outer plasma membrane leaflet and the sugar chains extended to the outer environment. Several lines of evidence suggest the importance of GSLs in various cellular processes such as differentiation, adhesion, proliferation, and cell-cell recognition. In pathogenic fungus Cryptococcus neoformans, glucosylceramide serves as an antigen that elicits an antibody response in patients and it is essential for fungal growth in host extracellular environment. |
| COG1215 | BcsA | 7.97e-15 | 1 | 332 | 22 | 357 | Glycosyltransferase, catalytic subunit of cellulose synthase and poly-beta-1,6-N-acetylglucosamine synthase [Cell motility]. |
| pfam13641 | Glyco_tranf_2_3 | 1.25e-06 | 46 | 261 | 2 | 214 | Glycosyltransferase like family 2. Members of this family of prokaryotic proteins include putative glucosyltransferase, which are involved in bacterial capsule biosynthesis. |
| cd00761 | Glyco_tranf_GTA_type | 5.43e-06 | 51 | 190 | 2 | 120 | Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QTO41435.1 | 2.87e-291 | 1 | 395 | 1 | 395 |
| QCC85255.1 | 2.05e-274 | 1 | 391 | 1 | 391 |
| VZH35393.1 | 1.19e-176 | 1 | 389 | 1 | 389 |
| SPD34223.1 | 2.31e-176 | 1 | 389 | 1 | 389 |
| ATD81518.1 | 2.31e-176 | 1 | 389 | 1 | 389 |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q5BL38 | 6.30e-07 | 8 | 156 | 11 | 161 | Ceramide glucosyltransferase OS=Xenopus tropicalis OX=8364 GN=ugcg PE=2 SV=1 |
| Q8AY29 | 1.48e-06 | 41 | 156 | 46 | 161 | Ceramide glucosyltransferase-A OS=Xenopus laevis OX=8355 GN=ugcg-a PE=1 SV=1 |
| Q16739 | 3.47e-06 | 29 | 156 | 34 | 161 | Ceramide glucosyltransferase OS=Homo sapiens OX=9606 GN=UGCG PE=1 SV=1 |
| Q5U4S8 | 8.13e-06 | 41 | 156 | 46 | 161 | Ceramide glucosyltransferase-B OS=Xenopus laevis OX=8355 GN=ugcg-b PE=2 SV=1 |
| Q9R0E0 | 8.13e-06 | 29 | 156 | 34 | 161 | Ceramide glucosyltransferase OS=Rattus norvegicus OX=10116 GN=Ugcg PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.997253 | 0.002699 | 0.000060 | 0.000007 | 0.000004 | 0.000010 |
