CAZyme Information: MGYG000002467_00043

Basic Information

• Species: Yersinia frederiksenii_C
• Lineage: Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Yersinia; Yersinia frederiksenii_C
• CAZyme ID: MGYG000002467_00043
• CAZy Family: GH103
• CAZyme Description: Membrane-bound lytic murein transglycosylase B

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
364	MGYG000002467_1|CGC1	40341.61	8.0689

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002467	4928795	Isolate	Finland	Europe

• Gene Location: Start: 49146; End: 50240 Strand: +

Full Sequence      

MVYGYPMRHLAVILPLLTLLSACSSKPTPPVAATPSDGLIQSGFLLEPQHMGHLENGDFA
YNADTARFVDKMVREHGFERQQLHDVLAQTQKLDWVIRLMDKQAPTSGRPSGPNGAWNRY
RNQFITPDNVQNGVNFWNQHQDALQRAYEKYGVPPEIIVGIIGVETRWGRVMGKTRIIDA
LATLSFAYPRRAEYFTGELETFLLMARAEGKDPLSLRGSYAGAMGYGQFMPSSFKSYAVD
FDGNGHINLWDPVDAIGSVANYFKSHGWTKGAAVAIPASGQAPNLDNGFKTKYPVSTLSA
AGLSPTSSLGEYQEASLLRLDVGSGYQYWYGLPNFYTITRYNHSTHYAMAVWQLGEAVGR
ARNL

Enzyme Prediction     

No EC number prediction in MGYG000002467_00043.

CAZyme Signature Domains

Family	Start	End	Evalue	family coverage
GH103	69	357	2.9e-97	0.9661016949152542

CDD Domains     

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
PRK10760	PRK10760	0.0	5	362	1	357	murein hydrolase B; Provisional
TIGR02282	MltB	3.05e-150	66	358	1	290	lytic murein transglycosylase B. This family consists of lytic murein transglycosylases (murein hydrolases) in the family of MltB, which is a membrane-bound lipoprotein in Escherichia coli. The N-terminal lipoprotein modification motif is conserved in about half the members of this family. The term Slt35 describes a naturally occurring soluble fragment of MltB. Members of this family never contain the putative peptidoglycan binding domain described by pfam01471, which is associated with several classes of bacterial cell wall lytic enzymes. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
COG2951	MltB	2.70e-123	5	362	1	339	Membrane-bound lytic murein transglycosylase B [Cell wall/membrane/envelope biogenesis].
pfam13406	SLT_2	4.45e-120	69	356	9	292	Transglycosylase SLT domain. This family is related to the SLT domain pfam01464.
TIGR02283	MltB_2	8.15e-55	120	359	54	299	lytic murein transglycosylase. Members of this family are closely related to the MltB family lytic murein transglycosylases described by TIGR02282 and are likewise all proteobacterial, although that family and this one form clearly distinct clades. Several species have one member of each family. Many members of this family (unlike the MltB family) contain an additional C-terminal domain, a putative peptidoglycan binding domain (pfam01471), not included in region described by this model. Many sequences appear to contain N-terminal lipoprotein attachment sites, as does E. coli MltB in TIGR02282. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]

CAZyme Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
ATM95015.1	1.53e-268	1	364	1	364
AJJ09680.1	3.44e-257	7	362	1	356
QDW32737.1	6.12e-257	1	362	1	362
AHM75072.2	3.41e-256	1	364	1	364
QAX79804.1	9.76e-256	1	364	1	364

PDB Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
1D0K_A	8.91e-181	45	362	1	320	ChainA, 35KD SOLUBLE LYTIC TRANSGLYCOSYLASE [Escherichia coli],1D0L_A Chain A, 35KD SOLUBLE LYTIC TRANSGLYCOSYLASE [Escherichia coli],1D0M_A Chain A, 35KD SOLUBLE LYTIC TRANSGLYCOSYLASE [Escherichia coli],1QDR_A Chain A, LYTIC MUREIN TRANSGLYCOSYLASE B [Escherichia coli],1QDT_A Chain A, LYTIC MUREIN TRANSGLYCOSYLASE B [Escherichia coli],1QUS_A Chain A, LYTIC MUREIN TRANSGLYCOSYLASE B [Escherichia coli],1QUT_A Chain A, LYTIC MUREIN TRANSGLYCOSYLASE B [Escherichia coli]
1LTM_A	3.37e-180	47	362	1	318	AcceleratedX-ray Structure Elucidation Of A 36 Kda Muramidase/transglycosylase Using Warp [Escherichia coli]
5O8X_A	9.92e-88	58	362	1	303	TheX-ray Structure of Catenated Lytic Transglycosylase SltB1 from Pseudomonas aeruginosa [Pseudomonas aeruginosa],5O8X_B The X-ray Structure of Catenated Lytic Transglycosylase SltB1 from Pseudomonas aeruginosa [Pseudomonas aeruginosa]
4ANR_A	6.82e-87	65	362	25	320	Crystalstructure of soluble lytic Transglycosylase SltB1 from Pseudomonas aeruginosa [Pseudomonas aeruginosa PAO1]
5ANZ_A	2.98e-26	101	357	86	342	CrystalStructure of SltB3 from Pseudomonas aeruginosa. [Pseudomonas aeruginosa],5AO7_A Crystal Structure of SltB3 from Pseudomonas aeruginosa in complex with NAG-anhNAM-pentapeptide [Pseudomonas aeruginosa]

Swiss-Prot Hits     

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P41052	6.34e-190	8	362	4	359	Membrane-bound lytic murein transglycosylase B OS=Escherichia coli (strain K12) OX=83333 GN=mltB PE=1 SV=1

SignalP and Lipop Annotations

This protein is predicted as LIPO

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000000	0.000002	1.000051	0.000000	0.000000	0.000000

TMHMM  Annotations     

There is no transmembrane helices in MGYG000002467_00043.