dbCAN-seq: a database of CAZyme sequence and annotation

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CAZyme Information: MGYG000002463_02577

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Basic Information help

Species

Pseudomonas aeruginosa

Lineage

Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas; Pseudomonas aeruginosa

CAZyme ID

MGYG000002463_02577

CAZy Family

GT1

CAZyme Description

O-mycaminosyltylonolide 6-deoxyallosyltransferase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
426	MGYG000002463_13\|CGC4	47072.83	8.5023

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002463	6750396	Isolate	Brazil	South America

Gene Location

Start: 308846; End: 310126 Strand: +

Full Sequence Download help

Enzyme Prediction help

No EC number prediction in MGYG000002463_02577.

CAZyme Signature Domains help

Family	Start	End	Evalue	family coverage
GT1	8	401	1.9e-46	0.9554973821989529

CDD Domains download full data without filtering help

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG1819	YjiC	1.17e-101	1	421	2	406	UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism].
cd03784	GT1_Gtf-like	5.03e-55	1	412	1	403	UDP-glycosyltransferases and similar proteins. This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.
pfam03033	Glyco_transf_28	7.76e-32	4	137	2	138	Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities.
PHA03392	egt	1.15e-08	222	360	273	409	ecdysteroid UDP-glucosyltransferase; Provisional
cd03785	GT28_MurG	5.36e-06	239	392	168	338	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.

CAZyme Hits help

Hit ID	Query Start	Query End	Hit Start	Hit End
AWS92657.1	1	426	1	426
AON41816.1	1	426	1	426
QEK41466.1	1	426	1	426
QII93292.1	1	426	1	426
ALY91563.1	1	426	1	426

PDB Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
1RRV_A	8.01e-21	1	388	1	376	X-raycrystal structure of TDP-vancosaminyltransferase GtfD as a complex with TDP and the natural substrate, desvancosaminyl vancomycin. [Amycolatopsis orientalis],1RRV_B X-ray crystal structure of TDP-vancosaminyltransferase GtfD as a complex with TDP and the natural substrate, desvancosaminyl vancomycin. [Amycolatopsis orientalis]
5XVM_A	1.78e-18	5	376	24	402	Sterol3-beta-glucosyltransferase (ugt51) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [Saccharomyces cerevisiae S288C],5XVM_B Sterol 3-beta-glucosyltransferase (ugt51) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [Saccharomyces cerevisiae S288C]
5GL5_A	1.92e-18	5	376	44	422	Sterol3-beta-glucosyltransferase (ugt51) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c): UDPG complex [Saccharomyces cerevisiae S288C],5GL5_B Sterol 3-beta-glucosyltransferase (ugt51) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c): UDPG complex [Saccharomyces cerevisiae S288C]
1IIR_A	1.36e-17	1	367	1	353	CrystalStructure of UDP-glucosyltransferase GtfB [Amycolatopsis orientalis]
6J31_A	7.46e-16	2	412	6	392	CrystalStructure Analysis of the Glycotransferase of kitacinnamycin [Kitasatospora],6J31_B Crystal Structure Analysis of the Glycotransferase of kitacinnamycin [Kitasatospora],6J31_C Crystal Structure Analysis of the Glycotransferase of kitacinnamycin [Kitasatospora],6J31_D Crystal Structure Analysis of the Glycotransferase of kitacinnamycin [Kitasatospora]

Swiss-Prot Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
O70023	6.10e-28	1	394	1	393	O-mycaminosyltylonolide 6-deoxyallosyltransferase OS=Streptomyces fradiae OX=1906 GN=tylN PE=1 SV=2
Q9AFC6	9.49e-23	1	361	1	349	Glycosyltransferase GtfE OS=Amycolatopsis orientalis OX=31958 GN=gtfE PE=3 SV=1
Q6C8M8	3.63e-20	5	387	999	1387	Sterol 3-beta-glucosyltransferase OS=Yarrowia lipolytica (strain CLIB 122 / E 150) OX=284591 GN=ATG26 PE=3 SV=3
Q9AFC7	1.37e-19	1	388	1	376	Devancosaminyl-vancomycin vancosaminetransferase OS=Amycolatopsis orientalis OX=31958 GN=gtfD PE=1 SV=1
P96560	6.18e-19	1	367	1	355	Glycosyltransferase GtfC OS=Amycolatopsis orientalis OX=31958 GN=gtfC PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
1.000043	0.000002	0.000000	0.000000	0.000000	0.000000

TMHMM Annotations help

There is no transmembrane helices in MGYG000002463_02577.