logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000002433_00208

You are here: Home > Sequence: MGYG000002433_00208

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Campylobacter_A concisus_P
Lineage Bacteria; Campylobacterota; Campylobacteria; Campylobacterales; Campylobacteraceae; Campylobacter_A; Campylobacter_A concisus_P
CAZyme ID MGYG000002433_00208
CAZy Family GT66
CAZyme Description Undecaprenyl-diphosphooligosaccharide--protein glycotransferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
430 MGYG000002433_5|CGC1 49460.44 7.9188
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002433 1923750 Isolate Denmark Europe
Gene Location Start: 43716;  End: 45008  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000002433_00208.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT66 2 313 4.6e-48 0.481962481962482

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG1287 Stt3 4.53e-08 8 218 315 538
Asparagine N-glycosylation enzyme, membrane subunit Stt3 [Posttranslational modification, protein turnover, chaperones].
pfam02516 STT3 1.44e-05 61 203 312 477
Oligosaccharyl transferase STT3 subunit. This family consists of the oligosaccharyl transferase STT3 subunit and related proteins. The STT3 subunit is part of the oligosaccharyl transferase (OTase) complex of proteins and is required for its activity. In eukaryotes, OTase transfers a lipid-linked core-oligosaccharide to selected asparagine residues in the ER. In the archaea STT3 occurs alone, rather than in an OTase complex, and is required for N-glycosylation of asparagines.
pfam18527 STT3_PglB_C 4.84e-05 321 390 10 79
STT3/PglB C-terminal beta-barrel domain. Asparagine-linked glycosylation is a post-translational modification of proteins containing the conserved sequence motif Asn-X-Ser/Thr. The attachment of oligosaccharides is implicated in diverse processes such as protein folding and quality control, organism development or host-pathogen interactions. The reaction is catalysed by oligosaccharyltransferase (OST), a membrane protein complex located in the endoplasmic reticulum. The central, catalytic enzyme of OST is the STT3 subunit, which has homologues in bacteria and archaea. Structural analysis of a bacterial OST, undecaprenyl-diphosphooligosaccharide protein glycotransferase EC:2.4.99.19 (PglB) protein, revealed two domains: a transmembrane domain and a periplasmic domain. This entry represents the C-terminal periplasmic beta-barrel domain.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
ALF48124.1 1.16e-287 1 430 277 706
QPI01678.1 1.45e-286 1 430 279 708
QPH99886.1 1.45e-286 1 430 279 708
QPI03445.1 2.76e-284 1 430 279 708
QPH88497.1 2.76e-284 1 430 279 708

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
3RCE_A 6.91e-61 9 429 281 711
Bacterialoligosaccharyltransferase PglB [Campylobacter lari]
5OGL_A 1.08e-57 9 429 281 711
Structureof bacterial oligosaccharyltransferase PglB in complex with an acceptor peptide and an lipid-linked oligosaccharide analog [Campylobacter lari RM2100]
6GXC_A 1.24e-57 9 429 281 711
Bacterialoligosaccharyltransferase PglB in complex with an inhibitory peptide and a reactive lipid-linked oligosaccharide analog [Campylobacter lari RM2100]
3AAG_A 7.46e-37 157 430 9 291
Crystalstructure of C. jejuni pglb C-terminal domain [Campylobacter jejuni RM1221],3AAG_B Crystal structure of C. jejuni pglb C-terminal domain [Campylobacter jejuni RM1221]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q5HTX9 8.82e-64 9 430 279 713
Undecaprenyl-diphosphooligosaccharide--protein glycotransferase OS=Campylobacter jejuni (strain RM1221) OX=195099 GN=pglB PE=1 SV=1
Q0P9C8 2.37e-63 9 430 279 713
Undecaprenyl-diphosphooligosaccharide--protein glycotransferase OS=Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168) OX=192222 GN=pglB PE=1 SV=1
B9KDD4 4.44e-60 9 429 281 711
Undecaprenyl-diphosphooligosaccharide--protein glycotransferase OS=Campylobacter lari (strain RM2100 / D67 / ATCC BAA-1060) OX=306263 GN=pglB PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.999982 0.000037 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      download full data without filtering help

start end
52 74
81 98
102 124
133 152