dbCAN-seq: a database of CAZyme sequence and annotation

You are browsing environment: HUMAN GUT

help

CAZyme Information: MGYG000002398_01506

You are here: Home > Sequence: MGYG000002398_01506

Basic Information help

Species

Laribacter hongkongensis

Lineage

Bacteria; Proteobacteria; Gammaproteobacteria; Burkholderiales; Aquaspirillaceae; Laribacter; Laribacter hongkongensis

CAZyme ID

MGYG000002398_01506

CAZy Family

AA2

CAZyme Description

Catalase-peroxidase 2

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
754		81876.66	8.9153

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002398	3424272	Isolate	China	Asia

Gene Location

Start: 1527596; End: 1529860 Strand: +

Full Sequence Download help

Enzyme Prediction help

No EC number prediction in MGYG000002398_01506.

CAZyme Signature Domains help

Family	Start	End	Evalue	family coverage
AA2	94	195	2.1e-16	0.39215686274509803

CDD Domains download full data without filtering help

Cdd ID	Domain	qStart	qEnd	sStart	sEnd	Domain Description
cd00649	catalase_peroxidase_1	36	449	4	409	N-terminal catalytic domain of catalase-peroxidases. This is a subgroup of heme-dependent peroxidases of the plant superfamily that share a heme prosthetic group and catalyze a multistep oxidative reaction involving hydrogen peroxide as the electron acceptor. Catalase-peroxidases can exhibit both catalase and broad-spectrum peroxidase activities depending on the steady-state concentration of hydrogen peroxide. These enzymes are found in many archaeal and bacterial organisms, where they neutralize potentially lethal hydrogen peroxide molecules generated during photosynthesis or stationary phase. Along with related intracellular fungal and plant peroxidases, catalase-peroxidases belong to class I of the plant peroxidase superfamily. Unlike the eukaryotic enzymes, they are typically comprised of two homologous domains that probably arose via a single gene duplication event. The heme binding motif is present only in the N-terminal domain; the function of the C-terminal domain is not clear.
TIGR00198	cat_per_HPI	31	752	9	713	catalase/peroxidase HPI. As catalase, this enzyme catalyzes the dismutation of two molecules of hydrogen peroxide to dioxygen and two molecules of water. As a peroxidase, it uses hydrogen peroxide to oxidize donor compounds and produce water. KatG from E. coli is a homotetramer with two non-covalently associated iron protoheme IX groups per tetramer, but the ortholog from Synechococcus sp. is a homodimer with one protoheme. Important sites (numbered according to E. coli KatG) include heme ligands His-106 and His-267 and active site Trp-318. Note that the translation PID:g296476 from accession X71420 from Rhodobacter capsulatus B10 contains extensive frameshift differences from the rest of the orthologous family. [Cellular processes, Detoxification]
PRK15061	PRK15061	31	753	11	726	catalase/peroxidase.
cd08200	catalase_peroxidase_2	453	749	1	297	C-terminal non-catalytic domain of catalase-peroxidases. This is a subgroup of heme-dependent peroxidases of the plant superfamily that share a heme prosthetic group and catalyze a multistep oxidative reaction involving hydrogen peroxide as the electron acceptor. Catalase-peroxidases can exhibit both catalase and broad-spectrum peroxidase activities depending on the steady-state concentration of hydrogen peroxide. These enzymes are found in many archaeal and bacterial organisms where they neutralize potentially lethal hydrogen peroxide molecules generated during photosynthesis or stationary phase. Along with related intracellular fungal and plant peroxidases, catalase-peroxidases belong to plant peroxidase superfamily. Unlike the eukaryotic enzymes, they are typically comprised of two homologous domains that probably arose via a single gene duplication event. The heme binding motif is present only in the N-terminal domain; the function of the C-terminal domain is not clear.
COG0376	KatG	31	753	24	730	Catalase (peroxidase I) [Inorganic ion transport and metabolism].

CAZyme Hits help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
QZY04649.1	4.11e-284	37	753	4	715
QPC71243.1	2.36e-271	36	753	56	774
BCS01357.1	2.26e-28	75	436	6	270
BCS13101.1	2.26e-28	75	436	6	270
QQK46267.1	4.45e-26	75	436	5	269

PDB Hits download full data without filtering help

Hit ID	Query Start	Query End	Hit Start	Hit End	Description
5SXX_A	36	752	17	727	Crystalstructure of the E198A variant of Burkholderia pseudomallei catalase-peroxidase KatG with INH [Burkholderia pseudomallei 1710b],5SXX_B Crystal structure of the E198A variant of Burkholderia pseudomallei catalase-peroxidase KatG with INH [Burkholderia pseudomallei 1710b]
5SYW_A	36	752	17	727	Crystalstructure of Burkhoderia pseudomallei KatG variant Q233E [Burkholderia pseudomallei 1710b],5SYW_B Crystal structure of Burkhoderia pseudomallei KatG variant Q233E [Burkholderia pseudomallei 1710b]
5SYV_A	36	752	17	727	Crystalstructure of Burkholderia pseudomallei KatG N240D variant [Burkholderia pseudomallei 1710b],5SYV_B Crystal structure of Burkholderia pseudomallei KatG N240D variant [Burkholderia pseudomallei 1710b]
5SYU_A	36	752	17	727	Crystalstructure of Burkholderia pseudomallei KatG E242Q variant [Burkholderia pseudomallei 1710b],5SYU_B Crystal structure of Burkholderia pseudomallei KatG E242Q variant [Burkholderia pseudomallei 1710b]
5SYY_A	36	752	17	727	Crystalstructure of the S324G variant of catalase-peroxidase from B. pseudomallei [Burkholderia pseudomallei 1710b],5SYY_B Crystal structure of the S324G variant of catalase-peroxidase from B. pseudomallei [Burkholderia pseudomallei 1710b]

Swiss-Prot Hits download full data without filtering help

Hit ID	Query Start	Query End	Hit Start	Hit End	Description
Q1C435	4	753	4	735	Catalase-peroxidase OS=Yersinia pestis bv. Antiqua (strain Antiqua) OX=360102 GN=katG PE=3 SV=1
Q486C8	27	753	23	740	Catalase-peroxidase OS=Colwellia psychrerythraea (strain 34H / ATCC BAA-681) OX=167879 GN=katG PE=3 SV=1
Q2G479	15	749	19	745	Catalase-peroxidase OS=Novosphingobium aromaticivorans (strain ATCC 700278 / DSM 12444 / CCUG 56034 / CIP 105152 / NBRC 16084 / F199) OX=279238 GN=katG PE=3 SV=1
Q21DT6	22	753	18	738	Catalase-peroxidase OS=Saccharophagus degradans (strain 2-40 / ATCC 43961 / DSM 17024) OX=203122 GN=katG PE=3 SV=1
Q5QWH3	4	753	4	751	Catalase-peroxidase 2 OS=Idiomarina loihiensis (strain ATCC BAA-735 / DSM 15497 / L2-TR) OX=283942 GN=katG2 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000259	0.998994	0.000190	0.000191	0.000171	0.000146

TMHMM Annotations help

There is no transmembrane helices in MGYG000002398_01506.