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CAZyme Information: MGYG000002377_01780
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Clostridium_X cadaveris | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Clostridiales; Clostridiaceae; Clostridium_X; Clostridium_X cadaveris | |||||||||||
| CAZyme ID | MGYG000002377_01780 | |||||||||||
| CAZy Family | GH84 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 61596; End: 67175 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH84 | 188 | 485 | 3e-96 | 0.9932203389830508 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam07555 | NAGidase | 1.69e-121 | 188 | 484 | 1 | 293 | beta-N-acetylglucosaminidase. This family has previously been described as a hyaluronidase. However, more recently it has been shown that this family has beta-N-acetylglucosaminidase activity. |
| pfam02838 | Glyco_hydro_20b | 2.72e-23 | 41 | 181 | 1 | 123 | Glycosyl hydrolase family 20, domain 2. This domain has a zincin-like fold. |
| pfam00754 | F5_F8_type_C | 5.09e-13 | 651 | 778 | 1 | 127 | F5/8 type C domain. This domain is also known as the discoidin (DS) domain family. |
| pfam00754 | F5_F8_type_C | 1.08e-06 | 813 | 924 | 18 | 125 | F5/8 type C domain. This domain is also known as the discoidin (DS) domain family. |
| TIGR01167 | LPXTG_anchor | 4.55e-04 | 1822 | 1855 | 1 | 34 | LPXTG-motif cell wall anchor domain. This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other] |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QQY28342.1 | 0.0 | 13 | 1798 | 9 | 1667 |
| QQV04689.1 | 0.0 | 13 | 1798 | 9 | 1667 |
| QPS12841.1 | 0.0 | 13 | 1798 | 9 | 1667 |
| QMW73892.1 | 0.0 | 13 | 1798 | 9 | 1667 |
| AYE33607.1 | 0.0 | 8 | 1361 | 11 | 1360 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 6PWI_A | 1.95e-182 | 35 | 637 | 27 | 626 | Structureof CpGH84D [Clostridium perfringens ATCC 13124],6PWI_B Structure of CpGH84D [Clostridium perfringens ATCC 13124] |
| 6PV4_A | 1.77e-140 | 42 | 643 | 32 | 652 | Structureof CpGH84A [Clostridium perfringens ATCC 13124],6PV4_B Structure of CpGH84A [Clostridium perfringens ATCC 13124],6PV4_C Structure of CpGH84A [Clostridium perfringens ATCC 13124],6PV4_D Structure of CpGH84A [Clostridium perfringens ATCC 13124] |
| 2XPK_A | 1.69e-71 | 31 | 612 | 3 | 565 | Cell-penetrant,nanomolar O-GlcNAcase inhibitors selective against lysosomal hexosaminidases [Clostridium perfringens],2XPK_B Cell-penetrant, nanomolar O-GlcNAcase inhibitors selective against lysosomal hexosaminidases [Clostridium perfringens] |
| 7KHV_A | 7.66e-71 | 31 | 612 | 3 | 565 | CpOGAIN COMPLEX WITH LIGAND 54 [Clostridium perfringens],7KHV_B CpOGA IN COMPLEX WITH LIGAND 54 [Clostridium perfringens],7KHV_C CpOGA IN COMPLEX WITH LIGAND 54 [Clostridium perfringens],7KHV_D CpOGA IN COMPLEX WITH LIGAND 54 [Clostridium perfringens],7KHV_E CpOGA IN COMPLEX WITH LIGAND 54 [Clostridium perfringens],7KHV_F CpOGA IN COMPLEX WITH LIGAND 54 [Clostridium perfringens] |
| 2CBI_A | 1.90e-70 | 31 | 612 | 3 | 565 | Structureof the Clostridium perfringens NagJ family 84 glycoside hydrolase, a homologue of human O-GlcNAcase [Clostridium perfringens],2CBI_B Structure of the Clostridium perfringens NagJ family 84 glycoside hydrolase, a homologue of human O-GlcNAcase [Clostridium perfringens],2CBJ_A Structure of the Clostridium perfringens NagJ family 84 glycoside hydrolase, a homologue of human O-GlcNAcase in complex with PUGNAc [Clostridium perfringens],2CBJ_B Structure of the Clostridium perfringens NagJ family 84 glycoside hydrolase, a homologue of human O-GlcNAcase in complex with PUGNAc [Clostridium perfringens],2V5C_A Family 84 glycoside hydrolase from Clostridium perfringens, 2.1 Angstrom structure [Clostridium perfringens],2V5C_B Family 84 glycoside hydrolase from Clostridium perfringens, 2.1 Angstrom structure [Clostridium perfringens],2VUR_A Chemical dissection of the link between Streptozotocin, O-GlcNAc and pancreatic cell death [Clostridium perfringens],2VUR_B Chemical dissection of the link between Streptozotocin, O-GlcNAc and pancreatic cell death [Clostridium perfringens],2X0Y_A Screening-based discovery of drug-like O-GlcNAcase inhibitor scaffolds [Clostridium perfringens],2X0Y_B Screening-based discovery of drug-like O-GlcNAcase inhibitor scaffolds [Clostridium perfringens] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P26831 | 6.06e-249 | 42 | 1459 | 39 | 1491 | Hyaluronoglucosaminidase OS=Clostridium perfringens (strain 13 / Type A) OX=195102 GN=nagH PE=1 SV=2 |
| Q8XL08 | 5.05e-69 | 20 | 612 | 22 | 595 | O-GlcNAcase NagJ OS=Clostridium perfringens (strain 13 / Type A) OX=195102 GN=nagJ PE=1 SV=1 |
| Q89ZI2 | 8.23e-69 | 134 | 565 | 100 | 524 | O-GlcNAcase BT_4395 OS=Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) OX=226186 GN=BT_4395 PE=1 SV=1 |
| Q0TR53 | 8.99e-69 | 20 | 612 | 22 | 595 | O-GlcNAcase NagJ OS=Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / Type A) OX=195103 GN=nagJ PE=1 SV=1 |
| O60502 | 3.06e-23 | 189 | 483 | 63 | 370 | Protein O-GlcNAcase OS=Homo sapiens OX=9606 GN=OGA PE=1 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000406 | 0.998746 | 0.000258 | 0.000217 | 0.000178 | 0.000156 |
